Enhanced Recovery for Colorectal Patients

Enhanced Recovery for Colorectal Patients Caroline Jenkins and Inge Bateman Department of Anaesthesia, Worthing Hospital Western Sussex Hospitals NHS...
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Enhanced Recovery for Colorectal Patients

Caroline Jenkins and Inge Bateman Department of Anaesthesia, Worthing Hospital Western Sussex Hospitals NHS Trust

Aims of the Session 





Inform you of how we manage analgesia for ER patients at Worthing Hospital

Inform you of what they do elsewhere with reference to analgesia for ER patients Forum for discussion of current practice

Definition ‘An evidence based approach involving a select number of interventions which, when implemented as a group, demonstrate a greater impact on outcomes than when implemented as individual interventions.’ Enhanced Recovery Partnership Programme March 2010

Do you do ER? If so what approach do you use?

Enhanced Recovery 

Henrik Kehlet Denmark 1990s



Delivered in UK since the early 2000s

http://www.scitopics.com/Enhanced_Recovery_after_Surgery.html Kahokehr A, Sammour T, Zargar-Shoshtari K, Hill AG

Background of Enhanced Recovery at Worthing Hospital 





2007 project team set up for ER, agreed no patient selection (i.e. all inclusive service) 2008 first patients on ER pathway PCA, Paracetamol & NSAID. Epidural on indication. 2009 ER Nurse Specialist appointed TAP blocks, Ketamine, Paracetamol & NSAID, PCA or Morphine oral solution regularly & PRN. Epidural on indication. With review of patients’ requirements for regular Morphine oral solution we changed the regime to PRN only and PCA on indication.

Pre-admission Counselling

Audit

No Bowel Prep

CHO load Pre-op fasting

Oral Nutrition

Catheters

Premedication

Gut motility

NG Tubes

Enhanced Recovery after Surgery

Opioid sparing

PONV

Analgesics

Anaesthetic

Mobilisation Temperature Adapted from Fearon et al 2005

Fluids Incisions

Different Approaches to ER       

Epidural Spinal PCA Oral analgesia TAP blocks Local infiltration Ketamine

Benefits of Epidurals Thoracic is the classic approach 

 

Reduction in pituitary, adrenocortical & sympathetic response Opioid sparing Does not modify immunological or inflammatory response

Problems Associated with Epidurals    



Hypotension Fluid ‘overload’ Slower to mobilise and eat Longer length of stay Failure

Benefits of Spinals   

Improved mobilisation Reduced opioid requirement Fewer complications than epidurals

Problems Associated with Spinals 



Risk of exaggerated cardiovascular changes Risk of high block

What we do in Worthing Pathway of a typical ER patient

The Enhanced Recovery Patient Pathway Mr. C.R. 65 years old. 70Kg with a BMI of 24. Surgical procedure: High Anterior Resection PMH: Fit & No medications Non-Smoker

Pre-op Assessment Standard including bloods/ECG

ERP Nurse facilitator present ERP explained => clear expectations  Ileostomy information offered  Discharge planning commenced 

Admission Night Before   

Bowel preparation Carbohydrate drink 800mL midnight Access to water until 6.00am

Surgery day   

CHO drink 200mL 2 hours pre-op Theatre 8.00 Standard Anaesthetic Dexamethasone 8mg IV Ketamine 40mg IV Paracetamol 1g IV Diclofenac 75mg IV



Oesophageal Doppler Cardiac monitor

Benefits of Ketamine  

Opioid sparing Reduces PONV

Zakine et al Anaesthesia and Analgesia Vol 106 (6) June 2008 1856-1860

Problems Associated with Ketamine  

Optimal regime not established IV preparation unpleasant taste

Zakine et al Anaesthesia and Analgesia Vol 106 (6) June 2008 1856-1860

Operation



Laparoscopic sigmoid colectomy Small incision to remove specimen Duration – 150minutes



TAP block at the end of surgical procedure

 

Transversus Abdominis Plane Block   

Ultrasound guided or blind technique Easy to learn Opioid sparing effect for open & lap surgery

McDonnell JG et al. Anesth Analg 2007;104:193-197 El-Dawlatly AA et al. BJA 2009;102:763-7

Transversus Abdominis Plane Block 



Sensory supply from anterior rami of lower 6 thoracic nerves Fascial plane between internal oblique & transversus abdominis

TAP Block Using Ultra Sound Sterile Procedure  Sterile field  U/S probe protected  Patient position  Needle selection: regional block or Tuohy needles  Bilateral blocks 2 x 20mL 0.25%-0.5% chirocaine

Performing a TAP Block Using Ultra Sound  

   

Identify landmarks Advancement perpendicular to skin via Petit’s triangle with classical 2 pops Oblique approach posterior to mid axillary line with real-time ultrasound guidance Tissue compression aids clarity of image Needle tip placement observed Small volume injections assist confirmation of needle position

TAP Block Using Ultra Sound

http://www.medclip.com/scr/bd/8c/b5/bd8cb579349ec4f_2.jpg

TAP Block Using Ultra Sound

http://www.usra.ca/files/images/tap7.jpg

Performing a TAP Block (blind) 2 pops & a squirt 1. External oblique fascia 2. Internal oblique fascia transversus abdominis plane

Post-op Analgesia   



Paracetamol 1g QDS PO Ibuprofen 400mg QDS PO Ketamine 20mg 4 hourly S/L (for 48 hours) Morphine oral solution PRN (no post-op morphine used at all)

Morphine IV rescue analgesia for Recovery – not used

Post-op Day of Surgery   



No nasogastric tube, No drain Return to ward 14.30 Free Fluids – resource drinks Out of bed 2 hours

Day 1 Post-op       

Drip down, catheter out Out of bed 08.00 3 x 60m walks, Self washing etc. 4 resource drinks Breakfast, lunch, dinner and snacks WR Note – Home later today or tomorrow Acute Pain Ward Round – pain well controlled on mobilisation, deep breathing and coughing

Day 2 Post-op Ward Round Doing well  Eating and drinking  Passing flatus  Home 

Follow up by phone calls by ER nurse specialist

Recap of Analgesia used for ER Patients at Worthing

Per-op Analgesia 

  

Epidural on indication Fentanyl Paracetamol IV Ketamine 0.5mg/kg between induction & incision

 



Morphine NSAID IV TAP block end of surgical procedure

Post-op Analgesia



Regular Paracetamol 1g QDS PO Regular NSAID PO Ketamine 15-20mg 4 hourly S/L (for 48 hours) Morphine oral solution PRN Occasionally PCA



Epidural on indication

  



Programme Figures in Relation to LOS 2002

2008

2009

2010 (so far)

Mean

11.5

Median 12

10

6.5

6.1

8

5

5

Readmission Rates 2008

2009

2010 (so far)

13%

11%

4.8%

CHKS Data  

F.31 Complex large intestine F.32 Very Complex large intestine

2009 Worthing lower lengths of stay than our peer hospitals.

Department of Health HES Data for elective colorectal resection in England 2009 Length of stay by volume of cases, provider 2008-09 prov. to Dec:

Colorectal resection No. completed elective cases

200

Current Worthing ER

180

Length of stay

160 140 120 100 80 60 40 20 0 -

2.0

4.0

6.0

8.0

10.0

12.0

Mean length of stay (days)

14.0

16.0

18.0

20.0

Summary Worthing hospital currently use an effective ER regime without use of Epidural, Spinals or PCA that shows reduction in L.O.S and readmissions rates. The research will be started shortly to add evidence to the clinical findings.

Any Questions

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