PRODUCT INFORMATION & MARKETING SUPPORT •

Product Features and Benefits

•

Manufacturing procedures and protocols

•

• • • •

Product Maintenance

Accuracy & Precision Comparison Tables Competitive Analyses

Spare Part Diagrams and Listings Quality Certification

single channel models PIPET TING BUT TON larGe, rounded and eaSy o n t h e t h u m b . f r e e ly r o tat i n G u p p e r S e c t i o n p r e v e n t S a c c i d e n ta l v o lu m e c h a n G e

EJEC TOR T YPE 1

FING ER-HOOK

larGe

ta k e S t h e w e i G h t , f o r a more relaxed Grip

i m u m c o n ta c t

88

S u r fa c e a r e a f o r m a x -

pipet tinG ac tion uSinG EZI J E C T B U T TON r e q u i r e S o n ly m i n i m a l l at e r a l m o v e m e n t r e d u c i n G fat i G u e *

EJEC TOR T YPE 2 u n i q u e eZi j e c t ,

Side

ac tion but ton reduceS

REDESIG NED SOFT SPRING SYST EM

thumb movement

r e q u i r e S m u c h lo w e r preSSureS for pipettinG

PRECISION ENGI NEERED S ta i n l e S S S t e e l micrometer

VOLU ME SET TI N G U SI N G T HE PU SH-B UT TON (FOR RAPID/COARSE CHANGES) O R T HU MBW HEEL ( F O R F I N E / A C C U R AT E S E T T I N G )

12 12

CONTOU RED SHAPE i S c o m f o r ta b l e in either Small or larGe handS

DI G ITA L VOLU ME DI SPL AY with larGe e a S y-to - r e a d n u m b e r S

UV resistant axypets™ can be Safely SteriliSed with

COLOUR-CODED RIN GS

uv radiation - even prolonGed expoSure

for technique or owner i d e n t i f i c at i o n

Completely autoclavable for sensitive laboratory applications, all axypet™ models are fully autoclavable at 121°c / 0.1 mpa / 20 min. unlike many other “autoclavable” pipettes, axypet™ requires minimal accuracy checks and/or recalibration.

MATERIA LS U SED IN SI N G LE C HAN NEL A X YPETS H A N D L E - p o ly p r o p y l e n e (pp ) S H A F T N U T - p o ly p r o p y l e n e ( p p) E J E C T O R B U T T O N - p o ly p r o p y l e n e ( pp ) L E F T /R I G H T H A N D E J E C T O R B U T T O N - p o lya m i d e (pa) P U S H - B U T T O N : U P P E R PA R T S - p o ly p r o p y l e n e ( pp ) K N O B - p o lya m i d e (pa) L E N S - p o lyc a r b o n at e (p c ) S H A F T - p o ly v i n y l i d e n e f lu o r i d e ( p v df ) B U S H I N G - p o lya m i d e (pa) U P P E R A R B O R A N D E J E C T O R A R B O R - S ta i n l e S S S t e e l C O U N T E R W I N D O W - p o lyc a r b o n at e ( pc ) S T O P P E R B U S H I N G - p o lya m i d e ( pa) C O M P R E S S I O N B U S H I N G - p o ly p r o p y l e n e ( pp ) S E A L - p tf e O -RINGS - viton S P R I N G - S ta i n l e S S S t e e l (S S ) P I S T O N A S S E M B LY F O R 2 T O 2 5 0µ L m e d i c a l G r a d e S ta i n l e S S S t e e l , 31 6l P I S T O N A S S E M B LY F O R 1 000 , 5 0 0 0 A N D 1 0 , 0 0 0µ L p o ly p h e n y l e n e S u l p h i d e ( p pS)

PTFE/O-RI NG SealinG SyStem effective for over

60 ,00 0

c yc l e S

HEIGHT ADJUSTA BLE STA INLESS STEEL e jec tor to a c c o m m o d at e v i r t u a l ly a l l b r a n d S of tipS

C E MA R K

moulded into the pipe t te b o d y i S yo u r G ua r a n t e e o f conformit y

ACCU R ACY AND PREC ISION

STA INL ESS STEEL

i S G ua r a n t e e d o n ly w h e n a x y Gen tipS are uSed

piSton and SprinGS

multichannel models

8

PIPET TING B UT TON larGe, rounded and eaSy o n t h e t h u m b . f r e e ly r o tat i n G u p p e r S e c t i o n p r e v e n t S a c c i d e n ta l v o lu m e c h a n G e

12

EJECTOR T YPE 1

FINGER- HOOK

larGe

S u r fa c e a r e a f o r m a x i m u m c o n ta c t

8

ta k e S t h e w e i G h t , f o r a more relaxed Grip

PREC ISION ENG INEER ED

EJECTOR T YPE 2 u n i q u e eZ i j e c t ,

Side ac tion but ton requireS o n ly m i n i m a l l at e r a l movement reducinG fat i G u e

S ta i n l e S S S t e e l micrometer

VOLU ME SET TI N G U SI N G T HE PU SH-B U T TON (FOR RAPID/COARSE CHANGES) O R T HU MBW HEEL ( F O R F I N E / A C C U R AT E S E T T I N G )

REDESIGNED SOFT SPRING SYSTEM

12

CON TOURED SHA PE DI GITA L VOLU ME DI SPL AY

8

requireS much lo w e r p r e S S u r e S for pipettinG

12

i S c o m f o r ta b l e in either Small or larGe handS

with larGe e a S y-to - r e a d n u m b e r S

SU SPENSI ON SYSTEM a l lo w S e a c h S h a f t t o r e t r a c t i n d e p e n d e n t ly , w h e n p r e S S e d aGainSt a row of tipS, r e S u lt i n G i n a n e v e n S e a l i n G f o r c e a p p l i e d t o a l l t i p S and..

MA N I FOL D ROTAT ES 360°

. T I P S D O N OT FA L L O F F ! !!

for uSer comfort

MATERIAL S USED IN MULTICHA NNEL A X YPETS DU R A B L E SEA L I N G SYST EM effective for over 6 0 ,000 c yc l e S

CURVED EJECTOR BA R reduceS the force required for ejection

ACC U R AC Y A N D PR EC I SI ON i S G ua r a n t e e d o n ly w h e n a x yG e n tipS are uSed

H A N D L E - p o ly p r o p y l e n e (pp) S H A F T N U T - p o ly p r o p y l e n e (p p) E J E C T O R B U T T O N - p o ly p r o p y l e n e (pp) L E F T /R I G H T H A N D E J E C T O R B U T T O N - p o lya m i d e ( pa) P U S H - B U T T O N : U P P E R PA R T S - p o ly p r o p y l e n e ( p p ) K N O B - p o lya m i d e (pa) L E N S - p o lyc a r b o n at e (p c ) S H A F T S - p o ly v i n y l i d e n e f lu o r i d e (p vdf ) B U S H I N G - p o lya m i d e (pa) E J E C T O R A R B O R - S ta i n l e S S S t e e l C O U N T E R W I N D O W - p o lyc a r b o n at e (p c ) S T O P P E R B U S H I N G - p o lya m i d e (pa) C O M P R E S S I O N B U S H I N G - p o ly p r o p y l e n e ( p p ) P I S T O N A S S E M B LY f o r m u lt i c h a n n e l 10- S ta i n l e S S S t e e l ( S S) P I S T O N A S S E M B LY f o r m u lt i c h a n n e l 50 - p o ly p h e n y l e n e S u l p h i d e ( p p S) P I S T O N A S S E M B LY f o r m u lt i c h a n n e l 200, 3 0 0 - G l a S S M A N I F O L D H O U S I N G S - p o ly p r o p y l e n e (p p) E J E C TO R B A R , S H A F TS A N D P I S TO N S B OX E S - p o lya m i d e (pa)

maintenance procedures Cleaning - Sterilisation

• Clean external surfaces with isopropyl alcohol • Clean the plunger, seal and o-ring with distilled water.

88

• Loosen shaft nut • Autoclave at 121°C/0.1mPa/20 min. • Fasten shaft nut.

12 12

Cleaning the Plunger

• Take out plunger assembly from the shaft • Remember the order in which parts were assembled.

• Clean the plunger, o-ring and seal with distilled water • Cover the plunger with thin coat of grease.

• Relocate piston assembly and tighten locking nut • Pipette few times to let the parts position themselves.

Recalibration

• Determine temperature and pressure • Use distilled water • Determine inaccuracy error with an analytical balance (refer to manual).

• Remove the push-button • Insert calibration key • Holding thumbwheel, turn the calibration key as determined in manual.

• Check aspiration of the pipette.

maintenance procedures volume adjustment

88 • Push-button volume adjustment for fast counter rewinding.

• Single hand thumbwheel operation for precise volume setting.

• When setting the volume always decrease counter readout, ie reduce from higher setting to desired volume level.

• Adjustment of ejector stroke in 5 ml and 10 ml pipettes (+ejector caps).

• Application of ejector cap for narrow 10 μl tips and for low sealing 5 ml and 10 ml tips.

12 12

ejector adjustment

• If necessary, change spacers for non-Axygen 10 μl, 200 μl, 300 μl and 1000 μl tips.

autoclaving - AXYPET® is fully autoclavable • Loosen the shaft nut for autoclaving.

• Let the pipette cool down and dry after autoclaving. Don’t forget to tighten the shaft nut afterwards.

alll models

Routine pipette tests 1. Conformity to construction manual: a) Pipetting assembly check b) Pipette component aesthetics 2. pipetting assembly operation: a) Physical movement b) Pipetting forces

88

3. ejector assembly operation: a) Physical movement b) Effective tip ejection 4. pipette leak tightness: a) Static test (using tip) b) Dynamic test (liquid measurement)

12 12

5. Volumeter operation: a) Physical movement b) Counter working range for model c) Linearity of the counter figures d) Torque force required for adjustment

6. accuracy and precision (check using balance): a) Minimum volume test b) Maximum volume test tOtaL: 14 operations

Full Range tests: 1. Conformity to construction manual: a) Pipetting assembly check b) Pipette component aesthetics 2. pipetting assembly operation: a) Physical movement b) Pipetting forces c) Pipetting threshold, blowout threshold 3. push-button attachment 4. recalibration procedure 5. ejector assembly operation: a) Physical movement b) Effective tip ejection Routine pipette tests - quality procedures applied to each and every manufactured pipette

6. ejector fitting (removal and fitting): a) Ejector fitting (pulling force/ screwing force), b) Ejector push-button location c) Height adjustment spacer fitting d) Ejector cup fitting 7. pipette leak tightness: a) Static test (using tip) b) Dynamic test (liquid measurement) 8. Volumeter operation: a) Physical movement b) Counter working range for model c) Linearity of the counter figures d) Torque force required for adjustment 9. effectiveness of volume ‘locking’ 10. Dirt contamination on thumbwheel 11. amount of blowout 12. accuracy and precision (checking at the balance): a) Minimum volume test b) Mid-range test c) Maximum volume test 13. pipette reliability (endurance tests): a) Pipetting cycles (60,000) b) Counter rewinding (200) c) Push-button removal and refitting (200) d) Calibration screw operation e) Autoclaving (50) f ) Ejector operating (60,000) g) UV resistance (6 weeks continuous exposure) 14. resistance to vibrations 15. Climatic resistance: a) Cold resistance b) Dry heat resistance c) Humidity resistance tOtaL: 35 operations * Pipettes are usually checked with Standard test operations; Full range tests are used periodically, i.e. when new technical advancements are applied.

Full Range tests - tests applied to a range of pipettes periodically (for example, 4 years) or to a line which is either new or which has been subject of significant design or technological change

single channel models Maximum permissible systematic error Comparison – [ACCURACY] ISO 8655 Model

2

10

20

100

200

1000

5000

10000

Gilson Eppendorf Eppendorf Gilson Ultra Pipetman Research Reference

Volume

A%

A%

0.2

40

12

0.5

16

5

1

8

2

4

0.5

24

1.5

88 A%

A%

A%

Biohit mLine A%

Rainin Finnpipette Nichiryo EX Classic / Focus Plus Pipet-Lite A% A% A%

12

12

Ovation A%

Transferpette S

Socorex Accura

AXYPET

A%

A%

A%

6

12 1.85

2

2.7 1.5

Brand

9

5

1.5 5

1

12

2.5

2.5

2.5

2.5

2.5

5

2.4

1.5

1.5

1.5

1.5

1.5

10

1.2

1

1

1

1

1

5

5

3

12 12

2.5 1

2.7

5

2.7

1.5

3

1.5

5

5

2.5

2 2.5

7

1.5

1

1.5

1.6

1

1

1

1

1

7.5

5

7

5

2

4 0.16 1 0.5 3

2

10

5

5

5

4

2

2

10

2

1

1

1.2

1.2

1.2

1.5

1

1.5

1.2

20

1

1

1

1

1

0.9

1

1

1

0.8

1

10

8

3

3

2

3.5

2

3.5

3

1

0.8

1

0.8

0.8

0.8

0.8

0.8

0.6

0.8

2.5

1

3

1

0.8 1.2 0.3 0.8 0.6

0.85 1

3

3

0.18 0.8

20

4

1.75

1.8

50

1.6

0.8

0.8

1

1

1

100

0.8

0.8

0.8

0.8

0.8

0.8

20

8

2.5

2.5

50

3.2

1†

1†

100

1.6

0.8

0.8

1

0.9

0.8

0.8

0.8

0.8

200

0.8

0.8

0.8

0.6

0.6

0.6

0.8

0.8

0.6

0.8

100

8

3

3

1.5

3

1

3

3

0.7

200

4

1.5∞

1.5∞

500

1.6

0.8

0.8

1

1

0.7

0.8

0.8

0.8

0.8

1000

0.8

0.8

0.8

0.6

0.6

0.6

0.8

0.7

0.8

0.6

1000

4

1.2

1.2

2000

2

0.6

0.6

2500

1.6

5000

0.8

0.6

0.6

0.6 3

0.8

2 1

1

0.6

0.8* 1.2

0.6*

0.6

0.6 0.1 0.6 0.5

0.6

0.8

0.8

0.6

0.6

0.6

xxx

xxx

6

5

2

3

xxx

xxx

6

3

3

3

1.5

1.5

5000

1.2

0.8

0.8

0.8

xxx

xxx

10000

0.6

0.6

0.6

0.6

xxx

xxx

AXYPET is better than competitor

xxx

2.5

xxx 0.6

1

0.8

0.8

xxx

0.8

0.6

0.4

0.6

xxx

0.5

* the volume for Eppendorf Reference pipette of volume range 500-2500µl † result obtained in 40-200 µl volume range ∞ result obtained in 200-1000 µl volume range

Competitor is better than AXYPET

0.7 0.6

3

0.5

1000

0.5

1.6 0.26

1

0.5

2000

0.8 1.6

AXYPET is same as competitor

Pipetman is a registered trademark of Gilson, Inc. Gilson is a trademarked term – owned by Gilson Inc. mLine is a registered trademark of Biohit OY. Biohit is a trademarked term – owned by Biohit OY. Transferpette is a trademark of Brand GmbH. Brand is a trademarked term – owned by Brand GmbH. Research Model Pipettors is a registered trademark of Eppendorf-Neth-Hinz GmbH. Eppendorf is a trademarked term – owned by Eppendorf AG. Finnpipette is a registered trademark of Thermo Electron Corp. Thermo Electron is a trademarked term – owned by Thermo Electron Corp. Inc. Rainin Pipet Lite is a registered trademark of Rainin Instruments Inc. Rainin Instruments is a trademarked term – owned by Mettler Toledo Inc. Rainin Classic is a registered trademark of Rainin Instruments Inc. Rainin Instruments is a trademarked term – owned by Mettler Toledo Inc. Nichipet EX is a registered trademark of Nichiryo. Nichiryo is a trademarked term – owned by Nichiryo Co. Ltd.. Ovation is a registered trademark of Vistalab Technologies. Vistalab Technologies is a trademarked term – owned by Vistalab Technologies Inc. Accura is a registered trademark of Socorex Isba SA. Socorex is a trademarked term – owned by Socorex Isba SA.

single channel models

Maximum permissible systematic error Comparison –

ISO 8655 Model

2

10

20

100

200

1000

5000

10000

Volume 0.2 0.5 1 2 0.5 1 5 10 2 5 10 20 10 20 50 100 20 50 100 200 100 200 500 1000 1000 2000 2500 5000 1000 2000 5000 10000

Gilson Eppendorf Eppendorf Gilson Ultra Pipetman Research Reference

P% 20 8 4 2 16 8 1.6 0.8 5 2 1 0.5 3 1.5 0.6 0.3 3 1.2 0.6 0.3 3 1.5 0.6 0.3 1.5 0.75 0.6 0.3 3 1.5 0.6 0.3

P% 6 2.5 0.7 1.25 0.6 0.4 1.5 0.8 0.5 0.3

88 P% 6 2.5

P%

P%

Rainin Nichiryo EX Finnpipette Classic / Focus Plus Pipet-Lite P%

1.25 0.6 0.4 1.5 0.8 0.5 0.3

0.4† 0.25 0.15

0.5 0.24 0.15 1 0.4† 0.25 0.15

0.3∞ 0.2 0.15 0.3 0.25

0.3∞ 0.2 0.15 0.3 0.25

0.16 0.6 0.3 0.2 0.16

0.16 0.6 0.3 0.2 0.16

Ovation

P% 6

P%

P% 7.6

1.3 0.7 2.8 1.2 0.6 0.4 2

2.5 1 3

1.8 0.9

1.8 0.8 0.4 1.5

1.8 0.8 0.4 1.5

4 1.5 1 0.6 2

0.6 0.3 1

0.6 0.3 0.7

1 0.4 1

0.3 0.2 0.7

0.3 0.15

0.4 0.15 0.8

0.3 0.3 0.2 0.3

0.3 0.15 0.7

0.2 0.2

0.2 0.2 0.2*

0.25 0.2 0.6

0.25 0.15 0.6

0.2*

0.3 0.15 xxx xxx xxx xxx

0.3 0.2 0.6

0.2 0.15

xxx xxx xxx xxx

2.0

Socorex Accura

P%

P%

Brand

AXYPET is better than competitor

1.5 2

1 0.5 3

1.2 0.6 0.4 2

4 1 0.5 2

0.5 1.7

0.5 0.3 1

1 0.4 1

0.5 0.3 1

0.7 0.4 1

0.5 1

0.24 0.15 1

0.3 0.3 0.5

0.24 0.15

0.4 0.2 0.6

0.2 0.6

0.6

0.25 0.15 0.6

0.3 0.2 0.5

0.6

0.3 0.2 0.6

0.2 0.5

0.2

0.2 0.15

0.3 0.2 0.3

0.2 0.15

0.3 0.2

0.2

0.2 3

0.2 0.16 0.6

0.3 0.2 0.4

0.3 0.2 0.6

0.3

0.2 0.16

0.3 0.2

0.3 0.2

0.5

1

0.2

* the volume for Eppendorf Reference pipette of volume range 500-2500µl † result obtained in 40-200 µl volume range ∞ result obtained in 200-1000 µl volume range

Competitor is better than AXYPET

Transferpette S

5

0.7

12 12

0.5 0.24 0.15

P%

Biohit mLine

[PRECISION]

AXYPET is same as competitor

Pipetman is a registered trademark of Gilson, Inc. Gilson is a trademarked term – owned by Gilson Inc. mLine is a registered trademark of Biohit OY. Biohit is a trademarked term – owned by Biohit OY. Transferpette is a trademark of Brand GmbH. Brand is a trademarked term – owned by Brand GmbH. Research Model Pipettors is a registered trademark of Eppendorf-Neth-Hinz GmbH. Eppendorf is a trademarked term – owned by Eppendorf AG. Finnpipette is a registered trademark of Thermo Electron Corp. Thermo Electron is a trademarked term – owned by Thermo Electron Corp. Inc. Rainin Pipet Lite is a registered trademark of Rainin Instruments Inc. Rainin Instruments is a trademarked term – owned by Mettler Toledo Inc. Rainin Classic is a registered trademark of Rainin Instruments Inc. Rainin Instruments is a trademarked term – owned by Mettler Toledo Inc. Nichipet EX is a registered trademark of Nichiryo. Nichiryo is a trademarked term – owned by Nichiryo Co. Ltd.. Ovation is a registered trademark of Vistalab Technologies. Vistalab Technologies is a trademarked term – owned by Vistalab Technologies Inc. Accura is a registered trademark of Socorex Isba SA. Socorex is a trademarked term – owned by Socorex Isba SA.

xxx xxx xxx xxx

AXYPET P% 6 1.63 1.3 0.7 2.8 0.58 0.6 0.4 1.5 0.34 0.5 0.3 0.8 0.28 0.24 0.2 0.6 0.18 0.25 0.2 0.4 0.26 0.2 0.15 0.25 0.14 0.2 0.15 0.6 0.3 0.2

single channel models

Competitive Analysis -

Gilson Pipetman P & Neo

Feature

axypet

pipetman

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Manufactured in France by Gilson Medical. One of the original manufacturers of digital pipettes. Have been making pipettes for over 35 years and so have a position of dominance in the world market. Probably still retain 30-40% of market, largely through strong brand awareness and high user loyalty.

Shape

Classic Gilson shape + more ergonomic handle Originator

Construction

Metal / Plastic

Metal / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Very High – mechanical / chemical / operational. Can go out of calibration when over-wound

Weight

Medium

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 18 specification points better

Customer perception of highest accuracy. Actually, 0 specification points better, ZERO !!

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 9 specification points better

Customer perception of highest precision. Actually, only 4 specification points better than AXYPET, 2 of which are in 10ml model, AXYPET beats it by 9 to 4

Pipetting Forces

Very low

Pipetman: Very High Pipetman Neo: High

Autoclavable

Fully

Liquid end only

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

1 year only

Tip Compatibility

Universal with adjustable tip ejector and ejector Gilson style tips (no tip ejector adjustment) caps

Calibration

Simple 2 minute operation

Sales Focus against Gilson Pipetman

1. Better ergonomics a. hook (finger rest) b. lower weight c. way lower pipetting forces d. more comfortable push-buttons 2. Better Accuracy and Precision 3. The same level of durability (we offer 3 year guarantee vs 1 year of Gilson) 4. Tip ejector a. adjustable height for tip compatibility b. easy to remove 5. Fully autoclavable

88

12 12

Heavy, due to use of metal internal mechanism and high density handle.

Requires to be done by service centre

Comparison of plunger Forces, 200µl

Comparison of plunger Forces, 1000µl

Comments / FAQ • Gilson sales force tends to use this argument against other pipette manufacturers. “Pipetman does Is grease on the not use grease because it could become a source of sample cross contamination. All others are plunger a potential bad cause they use grease” . This argument is completely false, having sold over 2 million pipettes, source of cross HTL/Axygen has never faced such a quality claim. Additionally, it may be worthwhile pointing out contamination? that Gilson’s newest pipette - Pipetman Ultra recommends the use grease as well! We can send you Gilson Ultra manual copy if you need to prove it. Is new Pipetman Neo a big improvement?

• Gilson Pipetman Neo is just a “cosmetically” improved Gilson Pipetman. Gilson reduced its pipetting force (still much higher than AXYPET) and added coloured push-buttons. After all, it’s the same Gilson Pipetman, so easy to beat!

* refer to Accuracy and Precision charts

Pipetman is a registered trademark of Gilson, Inc. Gilson is a trademarked term – owned by Gilson Inc.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis -

Gilson Pipetman Ultra

Feature

axypet

pipetman Ultra

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Manufactured in France by Gilson Medical. Introduced as successor of Pipetman 4-5 years ago. These electronic enriched pipettes (they are manual, not motorised) have a track record of 2 consecutive global recalls due to low reliability of electronics and their electrical circuits.

Shape

Classic Gilson shape + more ergonomic handle Classic Gilson shape + more ergonomic handle

Construction

Metal / Plastic

Metal / Plastic / Electronics

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Low – due to application of electronic components

Weight

Medium

Medium

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 18 specification points better !!

Customer perception of highest accuracy. Actually, 0 specification points better, ZERO !!

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 9 specification points better

Customer perception of highest precision. Actually, only 4 specification points better, 2 of which are in 10ml model, AXYPET beats it by 9 to 4

Pipetting Forces

Very low

Medium

Autoclavable

Fully

Liquid end only

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

1 year only

Tip Compatibility

Universal with adjustable tip ejector and ejector Universal with adjustable tip ejector and ejector caps button

Calibration

Simple 2 minute operation

Sales Focus against Gilson Pipetman Ultra

1. Comparable ergonomics with lower pipetting forces 2. Better Accuracy and Precision 3. Much higher durability mechanical / chemical a. fragile electronic components damaged also when flooded b. fragile ejector button prone to breakage c. fragile ejector adjustment system 4. Fully autoclavable 5. Much lower cost

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Comparison of plunger Forces, 200µl

Simple operation, although users find the calibration procedure unfriendly

Comparison of plunger Forces, 1000µl

Comments / FAQ Is Gilson Ultra LCD an important innovation in pipette industry?

LCD is “fancy”. It is advertised as a pro GLP feature (allowing the counting of pipetting cycles). However, its practical usefullness is questionable and is judged as such by many pipette users. By application of electronic components in Pipetman Ultra Gilson lost itself of its major strength – benchmark durability and reliability! Requires considerable service back up due to its fragile design

* refer to Accuracy and Precision charts

Pipetman is a registered trademark of Gilson, Inc. Gilson is a trademarked term – owned by Gilson Inc.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis Feature

Rainin Classic

axypet

rainin Classic

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Manufactured in US by Rainin Instruments Inc. Over 20 years, Rainin built its strength in the US based on exclusive distribution rights of Gilson Pipetman. Favourable contract conditions allowed it to develop its own pipettes (Pipet Lite and Pipet Class) whilst enjoying full control of Gilson Pipetman distribution. Despite aggressive promotion of the LTS system for years, Rainin pipettes (of which Pipet Lite is the more popular), could not match the original Pipetman popularity. Still heavily promoted as the “most ergonomic” pipette on the market.

Shape

Classic Gilson shape + more ergonomic handle Classic Gilson shape + more ergonomic handle

Construction

Metal / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Weight

Medium

Medium

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 18 specification points better

No historical data, seems to remain within specification over extended periods due to steel calibration screw construction. ZERO specification points better !!

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 7 specification points better

No historical data, seems to remain within specification over extended periods due to steel calibration screw construction. Only 3 specification points better, 2 of which are in 10ml model, AXYPET beats it by 7 to 3

Pipetting Forces

Very low

High, as in original Pipetman

Autoclavable

Fully

Liquid end only

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

3 years

Tip Compatibility

Universal with adjustable tip ejector and ejector Designed for standard Gilson style tips with no caps ejector adjustment

Calibration

Simple 2 minute operation

Sales Focus against Rainin Classic

1. Better ergonomics with lower pipetting forces a. much lower pipetting forces b. more comfortable push-buttons + EZIject system 2. Better Accuracy and Precision 3. Universal tip fit – adjustment of tip ejector 4. Fully autoclavable

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Metal / Plastic

Comparison of plunger Forces, 200µl

Requires to be done by service centre

Comparison of plunger Forces, 1000µl

Comments / FAQ Is Rainin Classic going to take over Gilson Pipetman market?

Rainin created an almost exact copy of Gilson Pipetman with all its weaknesses. Only its handle is slightly more comfortable due to its elongated, wide finger rest. Its operational forces are very high, its Accuracy and Precision rates are wider than AXYPET and its components are not fully autoclavable. AXYPET is more likely to address the needs of Gilson Pipetman users (depending on pipette model) together with systems allowing for effective reduction of ejection force - (EZIject) in single channel pipettes allowing more natural thumb movement - Moveable cones in multichannel pipettes allowing secure, even seal on all shafts with minimal force

* refer to Accuracy and Precision charts

Rainin Classic is a registered trademark of Rainin Instruments Inc. Rainin Instruments is a trademarked term – owned by Mettler Toledo Inc.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis Feature

axypet

Rainin Pipet Lite (LTS) rainin pipet Lite

Pipetting Forces

Manufactured in US by Rainin Instruments Inc. Over 20 years, Rainin built its strength in the US based on exclusive distribution rights of Gilson Manufactured in Poland by Axygen group Pipetman. Favourable contract conditions company HTL, ISO 9001/2000 certified allowed it to develop its own pipettes (Pipet Lite manufacturer with 26 years experience in and Pipet Class) whilst enjoying full control of pipette design and production, 3rd largest Gilson Pipetman distribution. Despite aggressive supplier of pipettes worldwide. Introduced late promotion of the LTS system for years, Rainin 2007. Designed to combine leading pipettes (of which Pipet Lite is the more popular), ergonomics, repeatability and reliability could not match the original Pipetman popularity. Still heavily promoted as the “most ergonomic” pipette on the market. Straight, unsophisticated, plain handle without Classic Gilson shape + more ergonomic handle thumbwheel Metal / Plastic Metal / Plastic Very High – mechanical / chemical / High. Locked Counter easily damaged if overoperational + “student proof” volume setting wound mechanism Medium Medium No historical data, seem to remain within Remains within specification over extended specification over extended periods due to steel periods, tested for 60,000 pipetting cycles. calibration screw construction. ZERO 18 specification points better specification points better !! No historical data, seem to remain within specification over extended periods due to steel Remains within specification over extended calibration screw construction. Only 3 periods, tested for 60,000 pipetting cycles. 7 specification points better specification points better, 2 of which are in 10ml model, AXYPET beats it by 7 to 3 Very low Very low –comparable / higher than AXYPET

Autoclavable

Fully

Liquid end only

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

History

Shape Construction Durability Weight Accuracy*

Precision*

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2 years Pipet Lite is promoted and known as the LTS pipette. Few users know that it is also offered in the standard tip fit version. Quite often their LTS Universal with adjustable tip ejector and ejector Tip Compatibility feature backfires as many users do not like to be caps bound to one brand of tips. (Few users are aware that Labcon make tips to fit Rainin LTS shafts). No adjustment of tip ejector Simple but requires special tools with deep reach. Calibration Simple 2 minute operation Requires to be done by service centre. 1. Comparable ergonomic a. comparable/slightly lower pipetting forces b. more comfortable handle (belly) c. more comfortable push-buttons Sales Focus against d. comparable low ejection force (EZIject system + moveable cones in multichannel) Rainin Pipet Lite 2. Better Accuracy and Precision 3. Universal tip fit – adjustment of tip ejector 4. Fully autoclavable Pipette not as durable. Tip shaft wears easily. Comments / FAQ Is Pipette Lite an ultimate solution for RSI risks?

Comparison of plunger Forces, 200µl

Comparison of plunger Forces, 1000µl

Without doubt, Pipet Lite has a reputation of a very ergonomic pipette. LTS tip ejection forces are lowest in the industry. On the other hand it is perceived as pipette dedicated only to LTS tips. AXYPET offers similar or lower pipetting

Is Pipet Lite volume counter lock the only AXYPET’s rotational top section of the push-button prevents volume change effectively and removes the need to perform additional operations - locking/unlocking prevention against accidental volume change?

* refer to Accuracy and Precision charts

Rainin Pipet Lite is a registered trademark of Rainin Instruments Inc. Rainin Instruments is a trademarked term – owned by Mettler Toledo Inc.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis -

Eppendorf Research

Feature

axypet

eppendorf research

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Manufactured in Germany by Eppendorf AG, a manufacturer with over 30 years of experience. Research pipette model was introduced 8 years ago and was revolutionary at that time. It quickly gained large portion of Gilson market share earning the reputation of a reliable and highly precise instrument. Eppendorf is the second largest supplier of pipettes worldwide.

Shape

Classic Gilson shape + more ergonomic handle Ergonomic, but wide handle with rear counter

Construction

Metal / Plastic

Metal / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

High but some components prone to breakage e.g. counter when over-wound. Counter assembly is very fragile. Ceramic piston in 100µl tends to break when not handled carefully

Weight

Medium

Medium

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 16 specification points better

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 10 specification points better

Pipetting Forces

Very low

Autoclavable

Fully

Liquid end only

UV Resistant

Yes, 6 weeks continuous exposure test

UV resistant

Warranty

3 years

3 years

Tip Compatibility

Universal with adjustable tip ejector and ejector Designed and calibrated for Eppendorf tips, no caps ejector adjustment

Calibration

Simple 2 minute operation

Sales Focus against Eppendorf Research

1. Comparable ergonomics with lower pipetting forces 2. Better Accuracy and Precision 3. Higher durability in some aspects a. ejector cannot be damaged when over-wound b. ejector does not wear off when taken off 4. Fully autoclavable 5. Universal tip fit 6. Eppendorf’s lower volume pipettes (2.5/10/20µl) – when parts require changing, the entire lower housing require replacement - very costly maintenance 7. Tedious to reassemble after autoclaving. Too many parts.

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Remain within specification over extended periods due to steel calibration screw construction. Reputation of highest Accuracy, but actually WORSE than AXYPET. ZERO specification points better !! Reducing tube in pipette easily dirtied and affects performance Remain within specification over extended periods. Reputation of highest Precision, but actually WORSE than AXYPET. Only 2 specification points better, both of which are in 10ml model, AXYPET beats it by 10 to 2 Medium, in model referred to as improved “Physio Care Concept”

Comparison of plunger Forces, 200µl

Simple operation

Comparison of plunger Forces, 1000µl

Comments / FAQ Some users believe that Eppendorf pipettes are the most reliable (repeatability + durability) in the marketplace

Don’t feel overwhelmed. Eppendorf brand is enhanced by its German origin and a good track record of their equipment reliability. Eppendorf pipettes are not “problem free” . Their ejectors break off through wear, their counters break when over-wound. With Axygen’s existing brand reputation, plus AXYPET’s outstanding durability, better ergonomics and repeatability you can offer an attractive and cost-effective, alternative to Eppendorf pipetting systems.

* refer to Accuracy and Precision charts

Research Model Pipettors is a registered trademark of Eppendorf-Neth-Hinz GmbH. Eppendorf is a trademarked term – owned by Eppendorf AG.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis Feature

Biohit mLine

axypet

Biohit mLine

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Manufactured in Finland by Biohit OY, a company established in 1998 by one of the key engineers of Finnpipette. Biohit built its reputation and strength on electronic pipettes - the first company to introduce such products. While its electronic pipettes were considered attractive, its inexpensive manual pipettes gained the reputation of being poor quality and highly defective. Biohit has attempted to reverse this position with its newest mLine models – introduced 3 years ago. Promoted as the most ergonomic in the industry.

Shape

Classic Gilson shape + more ergonomic handle Unique, flattened handle forcing a “side grip”

Construction

Metal / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Medium to low – hollow handle, plastic calibration screw and other components make the pipette prone to mechanical damage. Its Ulten (polyethylimide, PEI) plungers melt in chloroform

Weight

Medium

Low

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 9 specification points better

Deviates from specification, wider Accuracy tolerances due to plastic calibration screw. only one specification points better, AXYPET beats it by 9 to 1

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 14 specification points better

Deviates from specification, wider Precision tolerances due to plastic calibration screw. , Only 2 specification points better, AXYPET beats it by 14 to 2

Pipetting Forces

Very low

Very Low

Autoclavable

Fully

Fully

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

3 years

Tip Compatibility Calibration

Sales Focus against Biohit mLine

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Plastic / Plastic

Comparison of plunger Forces, 200µl

Universal with adjustable tip ejector and ejector Universal caps No adjustment of tip ejector Considered simple but more complex than the Simple 2 minute operation Proline model. Time consuming 1. Comparable ergonomics a. handle allowing for comfortable grip regardless of pipetting technique b. pipetting forces in the same lowest range (although mline is the leader) c. more comfortable push-buttons + eZiject system d. Similar movable cone system in multichannel pipettes 2. Better Accuracy and Precision 3. Higher mechanical and chemical durability 4. Adjustable tip ejector

Comparison of plunger Forces, 1000µl

Comments / FAQ Is mLine the most ergonomic pipette as claimed by Biohit? How to sell against mLine?

It is true that mLine pipettes offer lowest pipetting forces in the industry. However, they are not perfect from ergonomic & practical points of view though. Their flattened handle forces the user to hold the pipette in a very specific way (with finger hook facing aside). This technique is unfriendly and not very popular amongst end users. Don’t feel overwhelmed by mLine lowest pipetting forces. AXYPET is second best in the world. Most importantly we offer a unique combination of ergonomics, durability and repeatability. Biohit has a reputation of low reliability of their equipment – try to exploit it. Customers dislike the multichannel series as the tip cones dislodge easily and require constant service support.

* refer to Accuracy and Precision charts

mLine is a registered trademark of Biohit OY. Biohit is a trademarked term – owned by Biohit OY.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis -

Finnpipette Focus

Feature

axypet

Finnpipette Focus

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Shape

Classic Gilson shape + more ergonomic handle

Construction

Metal / Plastic

Manufactured by Thermo Fisher. Introduced 3 years ago - initially only in short shafted format which quickly proved unpractical (immediately started developing standard long shaft version). Advertised as very ergonomic with its adjustable handle size and low pipetting forces. A number of its features proved to be “over-engineered” Created with ergonomics in mind, but has a narrow finger rest which is uncomfortable in larger hands, and a defective handle size adjustment system Plastic / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Low - due to use of plastic components only and its handle size adjustment system (pipette tends to fall apart when dropped)

Weight

Medium

Low

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 5 specification points better

Very wide tolerances, deviates from specification due to use of plastic components (calibration screw). Only one specification point better !!

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 8 specification points better

Much wider tolerances, deviates from specification due to use of plastic components (calibration screw). ZERO specification points better !!

Pipetting Forces

Very low

Autoclavable

Fully

UV Resistant

Yes, 6 weeks continuous exposure test

Warranty

3 years Universal with adjustable tip ejector and ejector caps Simple 2 minute operation

Very Low but physically larger than AXYPET Fully, but recommends checking Accuracy and Precision after every cycle UV resistant. The handle however might change colour from grey to light yellow. If the inner parts of the pipette are exposed to UV light, it is necessary to check if there is sufficient grease on the piston and o-rings. 3 years Designed and calibrated for Finnpipette tips, no ejector adjustment Time consuming

Tip Compatibility Calibration

Sales Focus against Finnpipette Focus

Comments / FAQ 1 Is the Finnpipette Focus adjustable handle size a breakthrough in pipette ergonomics? 2. Are the short shafted pipettes popular amongst end users? 3. Is the Finnpipette Focus volume fast rewind system practical?

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1. Comparable ergonomics a. lower pipetting forces b. more comfortable (wider finger rest) 2. Way Better Accuracy and Precision a. tighter tolerances b. long lasting a&p due to steal calibration screw 3. Higher durability in some aspects a. well withstanding mechanical damage (drop) b. counter cannot be damaged when over-wound 4. Universal tip fit

Comparison of plunger Forces, 300µl†

Comparison of plunger Forces, 1000µl

1 Well, maybe the idea is good, but definitely not the one engineered by Finnpipette. Its adjustable handle system falls apart quite often when it is dropped. Additionally it is very hard to put the parts back together. 2. The experience of both Finnpipette and Capp which introduced their new pipettes in short shafted format proved that they were wrong. Their customers demanded short shafts for easier operation, but they quickly realised that they lack the reach in narrow tubes. Short shafted pipettes were disliked by the majority of users and Finnpipette and Capp immediately started developing the long shafted lines. An optimal shaft length, as used by AXYPET, seems to be the best approach. 3. The system requires the user to turn two mechanisms to set the volume (push-button to move first two digits and the collar below the push-button to move the last digit). It is almost impossible to perform the operation with one hand. Additionally it is hard to turn the volume setting collar (called by some users “the nail breaker”

* refer to Accuracy and Precision charts † Finnpipette not available in 200µl model

Finnpipette is a registered trademark of Thermo Electron Corp. Thermo Electron is a trademarked term – owned by Thermo Electron Corp. Inc.

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis Feature

Nichiryo Nichipet

axypet

nichiryo nichipet ex-plus

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Introduced 7 years ago by Nichiryo Co., a manufacturer of manual and electronic pipettes. It is perceived as the Japanese copy of Pipetman. Tends to be ‘old-styled’ in all its liquid handling products. Continuously upgraded but still lacks brand recognition (even in Japan). NPL model was launched in 2004 (Oct) to be marketed as a premium line as compared to their existing NPX model. But the only difference was the color and the one-touch calibration mechanism which proved to be very fragile.

Shape

Classic Gilson shape + more ergonomic handle

Construction

Metal / Plastic Very High – mechanical / chemical / operational + “student proof” volume setting mechanism Medium

Durability Weight

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Classic Gilson shape but longer handle with very short finger rest and no thumbwheel Metal / Plastic Medium, low durability of sealing system High

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 15 specification points better

Deviates from specification in use, with wider Accuracy tolerances. Only 4 specification points better, two of which are in 10ml model, AXYPET beats it by 14 to 4. Accuracy bad in certain volumes like NPL-20.

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 18 specification points better

Deviates from specification in use, with wider Precision tolerances. Only 2 specification points better. AXYPET beats it by 18 to 2. Locking device sometimes does not lock properly.

Pipetting Forces Autoclavable UV Resistant Warranty Tip Compatibility Calibration

Sales Focus against Nichiryo NIchipet Plus

Very low Fully Yes, 6 weeks continuous exposure test 3 years Universal with adjustable tip ejector and ejector caps Simple 2 minute operation

Medium Fully in EX Plus Yes, 60 day exposure but changes colour 2 years No ejector adjustment Difficult even for calibration labs

1. Better ergonomics a. much lower pipetting forces b. more comfortable handle (finger rest) c. more comfortable push-buttons + eZiject system 2. Much Better Accuracy and Precision 3. Universal tip fit – adjustment of tip ejector 4. Easily removable tip ejector 5. Adjustable tip ejector

Comments / FAQ Is Nichiryo volume setting lock a practical solution? Does Nichiryo stand up to the reputation of high quality, practicality and reliability of Japanese products?

Comparison of plunger Forces, 200µl

1. Volume adjusted only using push-button - no thumbwheel for fine adjustment. Some end users are attracted by the volume lock as in Nichiryo or Rainin Pipet Lite. In their opinion, only this mechanism guarantees that the volume setting would not change during prolonged pipetting sessions. They are wrong. The rotational top of AXYPET push-button fully prevents accidental volume change as well. It works as well as the lock but does not force the users to perform additional operations (locking / unlocking). Not surprisingly the volume lock (which has the tendency to jam if excessive force is applied, and can be quite painful to fingers) is the feature most commonly criticised by users working with Nichiryo pipettes 2. Despite marketing efforts of the manufacturer this pipette does not enjoy strong brand recognition. It’s low ergonomics, questionable volume lock and unpractical ejector fixing mechanism are criticised by the users. Furthermore Nichiryo pipettes are a nightmare to calibrate. 3. Volume button too small and tedious to grip when adjusting volumes. 4. A very heavy pipette, with very unspectacular specification.

* refer to Accuracy and Precision charts

Nichipet EX is a registered trademark of Nichiryo. Nichiryo is a trademarked term – owned by Nichiryo Co. Ltd..

Comparison of plunger Forces, 1000µl

Step 1 = initial inertia Step 3 = inertia to commence blow out

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis -

Brand Transferpette S

Feature

axypet

Brand transferpette s

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Produced in Germany by known glass manufacturer Brand GmbH. Its predacessor, Transferpette was not popular due to its odd (non standard) shape. The newest product of Brand, the Transferpette S, introduced 2 years ago seems to be a very well designed product.

Shape

Unique shape with comfortable finger rest and Classic Gilson shape + more ergonomic handle counter on the back - forces user into a sidepipetting action. No thumbwheel

Construction

Metal / Plastic

Plastic / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Medium to High

Weight

Medium

Low

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 15 specification points better

Seem to stay within specification over extended periods, but with wider Accuracy tolerances. Only 1 specification point better, AXYPET beats it by 14 to 1

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 18 specification points better

Seem to stay within specification over extended periods, butZero specification points better. AXYPET beats it by 14 to zero

Pipetting Forces

Very low

Medium

Autoclavable

Fully

Fully

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

3 years

Tip Compatibility

Universal with adjustable tip ejector and ejector Problems with 1000µl tips – their 1000µl pipettes caps have non standard cone diameter.

Calibration

Simple 2 minute operation

Sales Focus against Brand Transferpette S

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Comparison of plunger Forces, 200µl

Simple

1. Better ergonomics a. lower pipetting forces b. more comfortable push-buttons + eZiject system 2. Better Accuracy and Precision 3. Higher mechanical durability due to application of steel calibration screw

Comparison of plunger Forces, 1000µl

Comments / FAQ • A reasonably well designed product offering only reasonable accuracy and precision. Being of completely plastic construction, it does not enjoy the durability of AXYPET.

Step 1 = initial inertia Step 3 = inertia to commence blow out

* refer to Accuracy and Precision charts

Transferpette is a trademark of Brand GmbH. Brand is a trademarked term – owned by Brand GmbH.

Step 2 = aspiration Step 4 = blow out

single channel models

Competitive Analysis -

Socorex

Feature

axypet

socorex accura

History

Manufactured in Poland by Axygen group company HTL, ISO 9001/2000 certified manufacturer with 26 years experience in pipette design and production, 3rd largest supplier of pipettes worldwide. Introduced late 2007. Designed to combine leading ergonomics, repeatability and reliability

Manufactured in Switzerland by Socorex ISBA S.A. Introduced 3 years ago. Enjoys only limited popularity due to non standard design and relatively low durability.

Shape

Classic Gilson shape + more ergonomic handle

Characteristic, odd shape with ejector button in the front (on the finger hook)

Construction

Metal / Plastic

Plastic / Plastic

Durability

Very High – mechanical / chemical / operational + “student proof” volume setting mechanism

Medium to low – plastic calibration screw and “hollow” plastic body

Weight

Medium

Low

Accuracy*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 5 specification points better

Deviates from specification in use. Slightly better Accuracy tolerances. 6 specification point better, AXYPET has 5

Precision*

Remains within specification over extended periods, tested for 60,000 pipetting cycles. 8 specification points better

Deviates from specification in use, with wider Precision tolerances and with wider Precision tolerances. One point better. AXYPET beats it by 8 to 1

Pipetting Forces

Very low

Low, but higher than AXYPET - No exact data available.

Autoclavable

Fully

Fully

UV Resistant

Yes, 6 weeks continuous exposure test

No data

Warranty

3 years

3 years

Tip Compatibility

Universal with adjustable tip ejector and ejector Universal caps

Calibration

Simple 2 minute operation

Sales Focus against Socorex Accura

1. Better ergonomics a. lower pipetting forces b. more comfortable handle – conveniently located ejector button c. more comfortable push-buttons + eZiject system 2. Better Accuracy and Precision 3. Better mechanical durability

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Easy calibration system, but mechanism is fragile

Comments / FAQ • A reasonably well specified products. However, being of completely plastic construction, it does not enjoy the durability of AXYPET. Because of the positioning of the ejector button, it forces the user into a side pipetting position unlike the conventional situation where the ejector button is at the rear - this will definitely not suit everyone and should be exploited. • Not found in every market

* refer to Accuracy and Precision charts

Accura is a registered trademark of Socorex Isba SA. Socorex is a trademarked term – owned by Socorex Isba SA.

single channel models Spare Parts -

AP2 to AP250

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single channel models Spare Parts, Liquid End -

88

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AP2 to AP250

single channel models Spare Parts -

AP1000

88

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single channel models Spare Parts -

AP5000 to AP10ML

88

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single channel models Spare Parts Listing Item

1

Cat.no.

Part no.

Part name

Pipette type

19351

220.0110.7.8

Push-button

AP2

19353

220.0110.5.8

Push-button

AP10

19392

220.0110.12.8

Push-button

AP20

19393

220.0110.8.9

Push-button

AP50

19394

220.0110.13.8

Push-button

AP100

19395

220.0110.14.8

Push-button

AP200

19396

220.0110.2.8

Push-button

AP250

19397

220.0110.15.8

Push-button

AP1000

19358

220.0110.4.8

Push-button

AP250

19359

220.0110.11.8

Push-button

AP10ML

88

1A

19349

220.0101.1.0

Volume adjustment disc

AP

2

19326

220.0220.0.0

Upper arbor

AP

2A

19347

220.0202.0.0

Bushing

AP

3

9309

090.0400.0.0

Calibration knob

AP

3A

19309

090.0406.0.0

Thumbwheel

AP

4

9384

090.0420.2.0

Calibration screw

AP

5

9339

095.0402.0.0

6

9385

7

19629

8

12 12

Item

16

17

Cat.no.

Part no.

Part name

Pipette type

9011

001.0101.0.0

O-ring 0.74x1.02

AP2

9317

095.0102.0.0

O-ring 1.5x1.1

AP10, AP20

9098

098.0105.0.0

O-ring 3x2

AP50, AP100

29022

1373-200-341

O-ring 4.5x1.5

AP200, AP250

9358

097.0110.0.0

O-ring 8x2

AP1000

9254

089.0102.0.0

O-ring 18x2

AP5000

19002

001.0106.0.0

O-ring 25x2

AP10ML

19428

144.0400.8.4

Tip ejector

AP2, AP10

19429

145.0400.8.3

Tip ejector

AP20

19430

145.0400.8.2

Tip ejector

AP50, AP100

19431

144.0400.8.3

Tip ejector

AP200, AP250

19432

140.0400.8.1

Tip ejector

AP1000

19452

159.0400.0.0

Tip ejector

AP5000

19453

153.0400.0.0

Tip ejector

AP10ML

Screw

AP

090.0404.2.0

O-rng

AP

9643

191.0301.0.1

Shaft

AP2

260.0203.2.0

Shaft nut

AP2-AP1000

9642

094.0310.0.1

Shaft

AP10

19624

191.0310.1.0

Piston assembly

AP2

9367

095.0101.1.1

Shaft

AP20

19398

094.0200.1.0

Piston assembly

AP10

9652

198.0301.2.1

Shaft

AP50, AP100

19399

095.0700.1.0

Piston assembly

AP20

19400

098.0200.1.0

Piston assembly

AP50, AP100

9368

096.0101.1.1

Shaft

AP200, AP250

097.0101.1.1

Shaft

AP1000

18

29301

096.0300.1.0

Piston assembly

AP200, AP250

9369

29302

097.0400.4.0

Piston assembly

AP1000

9668

199.0301.1.1

Shaft

AP5000

9275

089.0200.3.0

Piston assembly

AP5000

19457

153.0330.0.1

Shaft

AP10ML

19482

153.0310.1.0

Piston assembly

AP10ML

20

9311

090.0403.0.0

X-ring

AP

9

29303

095.0108.4.0

Spring

AP2 -AP250

11

9320

095.0105.0.0

Stopper bushing

AP2 -AP250

21

9417

140.0410.0.1

Spacers set

AP2 - AP1000

22

19625 19626 19627 9438

260.0202.0.0 260.0205.0.0 260.0206.0.0 140.0203.0.0

Ejector button

Ejector arbor

AP AP AP AP2-AP1000

19402

140.0203.1.0

Ejector arbor

AP5000

12 13

9321

AP2 -AP250

29306

095.0107.0.1

Bushing

AP2 -AP250

191.0302.0.0

Compression bushing

AP2

9313

094.0101.0.0

Compression bushing

AP10

095.0104.0.0

Compression bushing

22A 25

AP20

Right Hand Push-button Left Hand Push-button

9363

098.0104.0.0

Compression bushing

AP50, AP100

25A

9397

PN/M-85111

Ring 3z

AP

9349

096.0103.0.0

Compression bushing

AP200, AP250

25B

19306

PN/M-85112

Ring 2.3z

AP5000

9357

097.0103.0.0

Compression bushing

AP1000

9256

089.0104.0.0

Compression bushing

AP5000

19464

153.0323.0.0

Compression bushing

AP10ML

9632

191.0303.0.0

Teflon seal

AP2

9096

034.0101.0.0

Teflon seal

AP10

9318 15

Compression spring

9631 9319 14

095.0106.0.0

095.0103.0.0

Teflon seal

19622

260.0200.1.0

Identification ring (6pcs.)

AP2-AP1000

19623

260.0200.2.0

Identification ring (10pcs.)

AP2-AP1000

27

9398

PN-78/82007

Washer 3.2

AP

27A

19410

140.0205.0.0

Washer

AP5000

AP20

28

19628

195.0103.1.0

Ejector spring

AP

26

9362

098.0103.0.0

Teflon seal

AP50, AP100

29

9663

195.0102.0.0

Rubber bushing

AP

29304

096.0102.0.1

Teflon seal

AP200, AP250

31

19454

159.0335.0.0

Filter

AP5000, AP10ML

9356

097.0102.0.0

Teflon seal

AP1000

9255

089.0103.0.0

Teflon seal

AP5000

32

153.0321.0.0

Teflon seal

AP10ML

159.0404.0.0 153.0404.0.0 221.0002.0.0

Ejector cap

19465

19466 19467 19378

AP5000 AP10ML AP2, AP10

33

9479

150.0010.0.0

Calibration key

AP2 -AP10

8-channel models

8 Spare Parts -

AP-8-10 to AP-8-300

12

8

12

12 Spare Parts -

12-channel models

AP-12-10 to AP-12-300

8

12

multichannel models Spare Parts Listing Item

Cat.no.

Part no.

Part name

Pipette type

29305

220.0110.10.8

Push-button

AP8/AP12-10

19393

220.0110.8.9

Push-button

AP8/AP12-50

19395

220.0110.14.8

Push-button

AP8/AP12-200

19373

220.0110.9.8

Push-button

AP8/AP12-300

1A

19349

220.0101.1.0

Volume adjustment disc

AP8/AP12

2

19326

220.0220.0.0.

Upper arbor

AP8/AP12

2A

19347

220.0202.0.0

Bushing

AP8/AP12

3

9309

090.0400.0.0

Calibration knob

AP8/AP12

3A

19309

090.0406.0.0

Thumbwheel

AP8/AP12

4

9384

090.0420.2.0

5

9339

095.0402.0.0

6

9385

7

1

88

12 12

Item

Cat.no.

Part no.

Part name

Pipette type

19591

180.0274.0.0

O-ring

AP8/AP12-10

19592

181.0274.0.0

O-ring

AP8/AP12-50

29023

1373-200-002

O-ring 3.9x1.8

AP8/AP12-200

29024

1373-200-001

O-ring 4.95x1.4

AP8/AP12-300

19595

180.0276.0.0

Washer

AP8/AP12-10

19596

181.0276.0.0

Washer

AP8/AP12-50

19597

182.0276.0.0

Washer

AP8/AP12-200

19598

183.0276.0.0

Washer

AP8/AP12-300

19599

180.0278.0.0

Spring

AP8, AP12

29540

184.0212.0.02+ 7pcs. 180.0211.0.0

Manifold housing back

AP12

29541

180.0212.0.02+7 pcs. 180.0211.0.0

Manifold housing back

AP8

19

29005

Screw M2.2x9.5

001.0208.0.0

AP8, AP12

20

9311

090.0403.0.0

X-ring

AP8, AP12

29542

180.0201.0.02

Manifold housing front

AP8

29543

184.0201.0.02

Manifold housing front

AP12

19625

260.0202.0.0

Ejector button

AP8, AP12

19626

260.0205.0.0

Right Hand Push-button AP8/AP12

19627

260.0206.0.0

Left hand Push-button

AP8/AP12

15

16

17

Calibration screw

AP8/AP12

Screw

AP8/AP12

090.0404.2.0

O-ring

AP8/AP12

19566

180.0240.0.0

Nut

AP8/AP12

7A

19569

180.0204.0.0

Cover nut

AP8/AP12

8

19570

180.0243.0.0

O-ring

AP8/AP12

9

29537

180.0301.1.0

Ejector pusher

AP8/AP12

19574

180.0214.0.10A

Ejector bar

AP8-10

19575

181.0214.0.11

Ejector bar

AP8-50

19576

181.0214.0.12

Ejector bar

AP8-200

19577

181.0214.0.13

Ejector bar

AP8-300

19578

184.0214.0.14A

Ejector bar

AP12-10

25

19402

140.0203.1.0

Ejector arbor

AP8, AP12

19579

185.0214.0.15

Ejector bar

AP12-50

25A

9397

PN/M-85111

Ring 3z

AP8, AP12

19580

185.0214.0.16

Ejector bar

AP12-200

25B

19306

PN/M-85112

Ring 2.3z

AP8, AP12

19581

185.0214.0.17

Ejector bar

AP12-300

26

29536

180.0209.1.0

Ring

AP8, AP12

19582

180.0260.0.0

Piston assembly

AP8/AP12-10

27

9398

PN-78/82007

Washer f3.2

AP8, AP12

19583

181.0260.0.0

Piston assembly

AP8/AP12-50

27A

19410

140.0205.0.0

Washer

AP8, AP12

29538

182.0260.1.0

Piston assembly

AP8/AP12-200 28

19628

195.0103.1.0

Ejector spring

AP8, AP12

29539

183.0260.1.0

Piston assembly

AP8/AP12-300 30

29001

001.0204.0.0

Screw M1.6x4-Ms

AP8, AP12

19586

180.0223.0.0

Piston spring

AP8, AP12

19587

180.0272.0.0

Shaft 10

AP8/AP12-10

31

29002

001.0205.0.0

Screw M1.6x6-Ms

AP8, AP12

19588

181.0272.0.0

Shaft 50

AP8/AP12-50

32

29003

001.0206.0.0

Screw M1.6x10-Ms

AP8, AP12

19589

182.0272.0.0

Shaft 200

AP8/AP12-200

33

29004

001.0207.0.0

Screw M1.6x16-Ms

AP8, AP12

19590

183.0272.0.0

Shaft 300

AP8/AP12-300

34

29006

001.0209.0.0

Screw M2.2x13

AP8, AP12

18

21

22

22A

11

12

13

14

demonstration case Comprising: AXYPET™ Single channel Pipette, 20-200µl AXYPET™ Single channel Pipette, 100-1000µl AXYPET™ Eight channel Pipette, 50-200µl MAXYMUM RECOVERY Demo Rack various accessories

88

12 12

AP-200 AP-1000 AP-8-200