In cosponsorship with

Transplant Center

Emerging Issues in Organ Transplantation – A Colloquium September 23 – 24, 2013 The Sanctuary at Kiawah Island | Kiawah Island, South Carolina

Register Today! ccfcme.org/gotransplant

Emerging Issues in Organ Transplantation – A Colloquium Emerging Issues in Organ Transplantation – A Colloquium will describe the current status of contentious issues in transplantation and consider their future implications with particular emphasis on the ultimate goal of enhancing patient care and research. This 1.5-day innovative conference is designed to juxtapose representatives from the academic, clinical, political, regulatory, industry, patient advocacy, and research communities and, thus, providing a forum for constructive debate on key issues in a highly visible and interactive environment. This conference will focus on current issues in the field that are in varied states of transition, including factors influencing organ allocation, extending Medicare reimbursement for transplant recipients, the impact of increased oversight of regulatory agencies on quality of care measures, and areas that have an impact on special populations. An additional key objective of the conference will be to provide stimulus for subsequent interactions between regulatory agencies, leaders in the transplant community, patient advocates, and clinicians to foster continued evolution of these discussions.

Who Should Attend? Physicians

Physician Assistants

Nurse Practitioners

Surgeons

Transplant Professionals

Transplant Administrators

Trainees

Nurses

By Attending You Will Learn How To: • Identify key factors affecting morbidity and mortality risks in living donation transplantation and their effect on donor programs • Explain living donor registry and disclosure of complications • Compare the available methods for measuring quality of life after transplantation • Describe the strategies to address the challenges associated with liver transplants, especially in patients with alcoholic cirrhosis disease • Summarize the trends and clinical impact of data on rejection and other endpoints in liver, lung, heart, kidney, and composite tissue transplants • Discuss strategies to address barriers to transplantation – socioeconomic, cultural, and educational methods to improve adherence

Conference Directors Titte R. Srinivas, MD Professor of Medicine Director, Transplant Nephrology Section Medical Director, Kidney and Pancreas Transplant Programs Division of Nephrology Medical University of South Carolina Charleston, SC Bijan Eghtesad, MD Department of General Surgery Digestive Disease Institute Transplant Center Cleveland Clinic Cleveland, OH Jesse Schold, PhD Associate Staff Director of Outcomes Research Department of Quantitative Health Sciences Cleveland Clinic Cleveland, OH

Faculty Kareem M. Abu-Elmagd, MD, PhD, FACS Director, Transplant Center Director, Center for Gut Rehabilitation and Transplantation (CGRT) Digestive Disease Institute Cleveland Clinic Cleveland, OH Prabhakar K. Baliga, MD Fitts-Raja Professor of Surgery Chief, Division of Transplant Surgery Medical University of South Carolina Charleston, SC D. Scott Batty Jr, MD CEO ImmunArray Ltd Richmond, VA Kenneth D. Chavin, MD, PhD Professor of Surgery, Microbiology & Immunology Vice-Chairman of Research, Department of Surgery Division of Transplant Medical University of South Carolina Charleston, SC Leonard Egede, MD, MS Professor Division of General Internal Medicine and Geriatrics Medical University of South Carolina Charleston, SC Stuart M. Flechner, MD, FACS Professor of Surgery/Urology Cleveland Clinic Lerner College of Medicine Glickman Urological and Kidney Institute Cleveland Clinic Cleveland, OH John Fung, MD, PhD Chairman, Digestive Disease Institute Cleveland Clinic Cleveland, OH Elisa Gordon, PhD, MPH Research Associate Professor Comprehensive Transplant Center and Center for Healthcare Studies Northwestern University Feinberg School of Medicine Chicago, IL Beverly Kosmach-Park, DNP Clinical Nurse Specialist Department of Transplant Surgery Children’s Hospital of Pittsburgh Pittsburgh, PA Kenneth McCurry, MD Program and Surgical Director Lung and Heart-Lung Transplantation Transplantation Center Digestive Disease Institute Department of Thoracic and Cardiovascular Surgery Heart and Vascular Institute Cleveland Clinic Cleveland, OH John W. McGillicuddy, MD Assistant Professor Department of Surgery Medical University of South Carolina Charleston, SC Charles Miller, MD Department of General Surgery Director, Liver Transplantation Transplantation Center Digestive Disease Institute Cleveland Clinic Cleveland, OH

Kenneth A. Newell, MD, PhD Professor of Surgery Vice Chair for Faculty Affairs Department of Surgery Emory University Atlanta, GA Robert O’Shea, MD, MSCE Assistant Professor, Cleveland Clinic Lerner College of Medicine Department of Gastroenterology and Hepatology Digestive Disease Institute Cleveland Clinic Cleveland, OH Elizabeth A. Pomfret, MD, PhD, FACS Chair, Department of Transplantation and Hepatobiliary Diseases Professor of Surgery Tufts University School of Medicine Lahey Medical Center Burlington, MA Don Rockey, MD Professor and Chairman Department of Medicine Medical University of South Carolina Charleston, SC Philip Schauer, MD Director, Advanced Laparoscopic and Bariatric Surgery Digestive Disease Institute Cleveland Clinic Cleveland, OH David Shaffer, MD Chief, Division of Kidney and Pancreas Transplantation Surgical Director, Kidney and Pancreas Transplantation Professor of Surgery Vanderbilt University Medical Center Nashville, TN David J. Taber, PharmD, BCPS Assistant Professor of Surgery Division of Transplant Surgery Medical University of South Carolina Charleston, SC Nicole A. Turgeon, MD, FACS Associate Professor of Surgery Department of Surgery/Transplant Emory Healthcare/Emory University Hospital Atlanta, GA Andreas G. Tzakis, MD, PhD, Dhc Mult Director, Transplant Center Digestive Disease Institute Cleveland Clinic Florida Weston, FL R. Matthew Walsh, MD, FACS Chairman Department of General Surgery Digestive Disease Institute Cleveland Clinic Cleveland, OH Nizar Zein, MD Department of Gastroenterology and Hepatology Transplantation Center Digestive Disease Institute Cleveland Clinic Cleveland, OH

Monday, September 23, 2013



7:00 am

Registration/Continental Breakfast/Exhibits

8:00 am

Welcome/Introductory Remarks Titte R. Srinivas, MD, and Bijan Eghtesad, MD

SESSION I:

Spotlight on Living Donation – Transparency of Process and Outcomes Moderators: Charles Miller, MD, and Kenneth D. Chavin, MD, PhD



8:10 am

Donor Deaths During Surgery Elisa Gordon, PhD, MPH



8:35 am

Trends in Living Donor Mortality Stuart M. Flechner, MD

8:55 am

The Need for a Living Donor Registry and Open Public Disclosure of Complications Elizabeth A. Pomfret, MD, PhD



9:15 am

Panel Discussion/Question and Answer Session



9:45 am

Refreshment Break/Exhibits

SESSION II:

Quality of Life After Transplantation Moderators: Andreas G. Tzakis, MD, PhD, and Titte R. Srinivas, MD

10:00 am

Behavioral Economics in Transplantation Nicole A. Turgeon, MD

10:20 am

Pediatric to Adult Transition: Challenges and Clinical Interventions Beverly Kosmach-Park, DNP

10:40 am

Paired Kidney Exchange – Opportunities and Challenges Kenneth A. Newell, MD, PhD

11:00 am

Do All Patients With Intestinal Failure Need Visceral Transplant? Kareem M. Abu-Elmagd, MD, PhD

11:20 am

Panel Discussion/Question and Answer Session

State of the Art Lecture Introduction: John Fung, MD, PhD 11:30 am

Inflammation, Fibrosis, and Allograft Failure: What We Can Learn From the Liver Don Rockey, MD

12:00 pm

Lunch

SESSION III: Transplantation: Focus on Liver and Pancreas Moderators: John Fung, MD, PhD, and Bijan Eghtesad, MD 1:00 pm

Should All Alcoholics Quit Before Being Listed for Transplantation? Robert O’Shea, MD



1:25 pm

NAFLD Nizar Zein, MD



1:50 pm

Reversal of the Metabolic Syndrome Philip Schauer, MD



2:15 pm

Islet Auto-transplantation: Chronic Pancreatitis and Beyond... R. Matthew Walsh, MD



2:40 pm

Panel Discussion/Question and Answer Session



3:00 pm

Refreshment Break/Exhibits





SESSION IV: Access to Transplantation and Adherence to Treatment Moderators: David Shaffer, MD, and Leonard Egede, MD 3:20 pm

Understanding Barriers to Transplantation: Socio Economic, Cultural, Educational, and Regional Prabhakar K. Baliga, MD

3:45 pm

Smart Phone and Telemedicine Approaches to Improve Adherence in the Transplant Clinic John W. McGillicuddy, MD



4:10 pm

Improving Value of Care Using a Multidisciplinary Approach David J. Taber, PharmD

4:35 pm

Panel Discussion/Question and Answer Session

5:00 pm

Adjourn



Tuesday, September 24, 2013

7:00 am

Continental Breakfast/Exhibits



8:00 am

Welcome/Introductory Remarks Titte R. Srinivas, MD, and Bijan Eghtesad, MD

SESSION V: Rethinking Endpoints for Clinical Trials Moderators: Bijan Eghtesad, MD, and Stuart M. Flechner, MD

8:05 am

Industry View on Endpoints for Clinical Trials D. Scott Batty Jr, MD

8:35 am

Panel on Clinical Trial Endpoints Liver Transplantation John Fung, MD, PhD

8:55 am

Lung Transplantation Kenneth McCurry, MD



9:10 am

Kidney Transplantation Titte R. Srinivas, MD



9:35 am

Panel Discussion/Question and Answer Session

10:00 am

Refreshment Break/Exhibits

SESSION VI: Collaborative To Improve Access and Outcomes – Consortium Development Moderators: Jesse Schold, PhD; Titte R. Srinivas, MD; and Kenneth A. Newell, MD, PhD 10:20 am

Open Discussion

• • •

Delineate Framework for Data Sharing Develop a Collaborative for Outcomes Research in Transplantation Incorporating Patient Level Data Accrual and Processing of Data Focused on Creating Value in Transplantation

11:50 am

Summary – Next Steps/Action Items

12:00 pm

Adjourn

special golf rates available We have arranged special golf rates for our attendees to play at any of the Five Championship Courses in South Carolina – Oak Point, Cougar Point, Turtle Point, Osprey Point, and The Ocean Course (with some additional fees). The rates include greens fees, golf cart, and range balls. Club rentals are available for $60 per set. To make your own tee time, please call 843.768.6000 or see the concierge for assistance. Be sure to tell them you are with “Emerging Issues in Transplantation” to get our special rates.

General Information Location The Sanctuary at Kiawah Island One Sanctuary Beach Drive Kiawah Island, SC 29455 Phone: 843.768.6000

Hotel Located along the pristine shores of Kiawah Island, South Carolina, this exquisitely designed oceanfront hotel, just 21 miles from downtown Charleston, captures the spirit, history, and charm of the beautiful south. Come walk through the front doors and experience a seaside mansion, where you will be surrounded by the grandeur of the architecture and hospitality at its finest. This beautiful seaside mansion is waiting to envelop you in its service and southern hospitality.

Hotel Accommodations A block of rooms has been reserved at The Sanctuary at Kiawah Island until August 21, 2013. To make your reservations, contact the Hotel Reservations Department at 800.654.2924. Please identify yourself as being with the Cleveland Clinic Emerging Issues in Organ Transplantation – A Colloquium, for a special rate of $345 single/ double plus tax.

Hotel Amenities • • • • • • •

World-Class Golf The Sanctuary Spa Pools (indoor and outdoor) Tennis Private Beach Nature Excursions Retail

Ground Transportation The Sanctuary is only 45 minutes from Charleston International Airport (CHS), and 15 minutes from Charleston Executive Airport (JZI). Transporation can be arranged from both airports through Kiawah Resort. Email [email protected] or call the Kiawah Resort Concierge at 843.768.6251

Parking Self parking – complementary Valet – $20 per night (plus tax)

Information For further information about this conference, contact the Cleveland Clinic Center for Continuing Education at: Local: 216.448.0770 Toll Free: 800.238.6750

Registration and Cancellation Preregistrations are accepted until 2:00 pm ET Friday, September 20, 2013. Register on site after this date. In case of cancellation, a full refund will be made if canceled by September 13, 2013. After September 13, 2013, a 50% cancellation fee will be deducted from your refund. Written notification of your cancellation is required to process your refund. NO REFUNDS WILL BE ISSUED AFTER October 31, 2013. For questions about registration, call 216.448.0777 or email us at [email protected].

Accreditation The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Cleveland Clinic Foundation Center for Continuing Education designates this live activity for a maximum of 11.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit. The Ohio Board of Nursing will accept at face value the number of contact hours awarded for an educational activity that has been approved for CE by a nationally accredited system of CE approval. Therefore, the 11.25 AMA PRA Category 1 Credits™ will be accepted for nursing credits.

Faculty Disclosure The Cleveland Clinic Foundation Center for Continuing Education has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education Standards for Commercial Support requiring resolution of all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified in the activity syllabus.

Web Address: ccfcme.org/gotransplant

Americans with Disabilities Act

Recording or reproducing of this course in any format is strictly prohibited.

The Cleveland Clinic Foundation Center for Continuing Education fully intends to comply with the legal requirements of the Americans with Disabilities Act. If you need assistance, please notify us at least two weeks prior to the activity.

Registration Form

Emerging Issues in Organ Transplantation – A Colloquium September 23 – 24, 2013 The Sanctuary at Kiawah Island | Kiawah Island, South Carolina

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Fees Fee Includes: Continental breakfasts, lunch, refreshment breaks, and electronic syllabus. On or Before August 23, 2013

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*Letter from program director is required to receive the discounted fee. If letter is not received two weeks prior to the activity, the full physician fee will be charged.

For registration questions, please email [email protected] or call 216.448.0777 Cleveland Clinic recognizes the importance of protecting the privacy and security of information provided to us. Therefore, we are no longer requesting credit card data in writing, including on registration forms or faxes. If you would like to register using a credit card, please log in to www.ccfcme.org/gotransplant or call 216.448.0777 where it will be handled directly by a certified processor.

Register Today! ccfcme.org/gotransplant

The Sanctuary at Kiawah Island | Kiawah Island, South Carolina

September 23 – 24, 2013

Emerging Issues in Organ Transplantation – A Colloquium The Cleveland Clinic Foundation 9500 Euclid Avenue Cleveland, OH 44195

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