Eliminating Mother-to-Child HIV Transmission in the U.S.: The Role of the FIMR-HIV Prevention Methodology

National FIMR Conference Friday, June 8, 2012 National Center for HIV/AIDS, Viral Hepatitis, STD & TB Prevention Division of HIV/AIDS Prevention

Estimated Annual Incidence of Perinatal HIV Infection, 33 States, HARS, 2003-2007 (N=463)

Estimated Cases/100,000 live births

5 4.5

4.5 (117 cases) 3.8 (100 cases)

4 3.5

3.1 (83 cases) 2.9 (80 cases)

3

3.0 (83 cases)

2.5 2 1.5 1 0.5 0 2003

2004

2005

2006

2007

Estimated annual incidence declined from 4.5 cases/100,000 live births (2003) to 3.0 cases/100,000 live births (2007). Taylor, et al. 6th IAS Conference, Rome. July 18, 2011

Estimated number of births to women living with HIV infection, 2000-2006

2006 estimate (8,650 – 8900) is ~30% > 2000 estimate (6075 – 6422)

Office of Inspector General (Fleming), 2002

Whitmore, et al. CROI, 2009

Elimination of Mother-to-Child HIV Transmission (EMCT) Goal 

MCT incidence < 1 per 100,000 live births 