Electronic Theses and Dissertations UC San Diego Peer Reviewed Title: Understanding the Relationship between Non-motor Symptoms of Parkinson's Disease and Sleep Disorders / Author: Neikrug, Ariel B. Acceptance Date: 2014 Series: UC San Diego Electronic Theses and Dissertations Degree: , Clinical psychologyUC San Diego Permalink: http://escholarship.org/uc/item/9rq6f90t Local Identifier: b8202842 Abstract: Non-motor symptoms (NMS) are common in Parkinson's disease (PD) and are considered the most disturbing symptoms to both patients and caregivers. Sleep disorders including rapideye-movement sleep behavior disorder (RBD), obstructive sleep apnea (OSA), restless legs syndrome (RLS), and periodic limb movement in sleep (PLMS) are common in and contribute to the disability of PD patients. This study evaluated the impact of sleep disorders on the NMS of PD. Eighty-six PD patients were evaluated and assessed for sleep disorders, sleepiness and the multiple NMS of PD. Principal component analyses and hierarchical multiple regression analyses were used to assess the relationship between the different NMS and the existence of sleep disorders. Results showed that sleep disorders are significant contributors to NMS in PD (p