Elizabeth B. Hirsch, PharmD, BCPS Assistant Professor Department of Pharmacy and Health Systems Sciences Northeastern University 360 Huntington Avenue, R218 TF, Boston, MA 02115 Phone: 617.373.7973 Fax: 617.373.7655 Email: [email protected]

EDUCATION/EMPLOYMENT HISTORY

Education 2008-2010

Infectious Diseases Pharmacotherapy Fellowship St. Luke’s Episcopal Hospital / University of Houston College of Pharmacy; Houston, TX

2007-2008

ASHP Accredited PGY1 Pharmacy Residency St. Luke’s Episcopal Hospital; Houston, TX

2007

Doctor of Pharmacy Bachelor of Health Sciences Creighton University School of Pharmacy and Health Professions; Omaha, NE

Employment history 2011-Present Assistant Professor Northeastern University; Boston, MA 2011-Present Clinical Pharmacist, Infectious Diseases / Antimicrobial Stewardship Team Beth Israel Deaconess Medical Center; Boston, MA 2010-2011

Research Assistant Professor University of Houston College of Pharmacy; Houston, TX

Licensures and certifications 2011-Present 2009-Present 2007-Present 2009-2011

Massachusetts State Board of Pharmacy, Licensed Pharmacist Board Certified Pharmacotherapy Specialist Texas State Board of Pharmacy, Licensed Pharmacist Texas State Board of Pharmacy, Pharmacist Preceptor

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SCHOLARSHIP/RESEARCH Major Areas of Research and Scholarship: Infectious Diseases Translational Research 1. Pharmacokinetics / pharmacodynamics of antimicrobials (PK/PD) 2. Mechanisms of bacterial resistance (BR) 3. Clinical outcomes of infection (CO)

Honors and awards 2013 2013 2012 2010 2010 2009 2005

The Rho Chi Society induction The Gerald Schumacher Pharmacy Faculty Award, Northeastern University School of Pharmacy Society of Infectious Diseases Pharmacists (SIDP) Young Investigator Research Award ASHP Best Practices Award (CASE) American Society for Microbiology ICAAC Fellows Grant Program American College of Clinical Pharmacy travel grant Phi Lambda Sigma-National Pharmacy Leadership Society induction

Refereed articles 2014

Hirsch EB, Raux BR, Lancaster JW, Mann RL, Leonard SN. Surface microbiology of the iPad tablet computer and the potential to serve as a fomite in both inpatient practice settings as well as outside of the hospital environment. PLoS One 2014; 9(10): e111250. Hirsch EB, Chang KT, Zucchi PC, Francoeur DN, Ledesma KR, Tam VH, Lasco TM. An evaluation of multiple phenotypic screening methods for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae. Journal of Infection and Chemotherapy 2014; 20(3):224-227.

2013

Hirsch EB, Guo B, Chang KT, Cao H, Ledesma KR, Singh M, Tam VH. Assessment of antimicrobial combinations for KPC-producing Klebsiella pneumoniae. Journal of Infectious Diseases 2013; 207(5):786-793.

2012

Tam VH, Hirsch EB, Lasco TM, Chang KT, Gentry LO, Palmer HR. Correlation of hospital carbapenem consumption and resistance trends in gram-negative bacteria. Annals of Pharmacotherapy 2012; 46(7-8):1120-1122. Tran TT, Palmer HP, Weston J, Hirsch EB, Shah DN, Cottreau J, Tam VH, Garey KW. Evaluation of a daptomycin dose optimization protocol: a potential policy for antibiotic stewardship programs. American Journal of Health-System Pharmacy 2012; 69(11):979984.

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Hirsch EB, Ledesma KR, Chang KT, Schwartz MS, Motyl MR, Tam VH. In vitro activity of MK-7655, a novel beta-lactamase inhibitor, in combination with imipenem against carbapenem resistant Gram-negative bacteria. Antimicrobial Agents and Chemotherapy 2012; 56(7):3753-3757. Bhagunde P, Chang KT, Hirsch EB, Ledesma KR, Nikolau M, Tam VH. A novel modeling framework to guide design of optimal dosing strategies for beta-lactamase inhibitors. Antimicrobial Agents and Chemotherapy 2012; 56(5):2237-2240. Hirsch EB, Cottreau JM, Caeiro JP, Johnson ML, Tam VH. A model to predict mortality following Pseudomonas aeruginosa bacteremia. Diagnostic Microbiology and Infectious Diseases 2012; 72(1):97-102. 2011

Hirsch EB, Cottreau JM, Ikwuagwu JO, Lusardi KT, Mohr JF, Rodriguez SM, Shah DN, Tran TT, on behalf of the Houston Infectious Diseases Network. Significant publications in infectious diseases pharmacotherapy in 2010. American Journal of Health-System Pharmacy 2011; 68(21):2075-2085. Hirsch EB, Chang KT, Lasco TM, Caeiro JP, Tam VH. Emergence of KPC-producing Klebsiella pneumoniae (KPC-Kp) in Texas. Diagnostic Microbiology and Infectious Diseases 2011; 69(2):234-235.

2010

Hirsch EB, Tam VH. Impact of multidrug-resistant Pseudomonas aeruginosa infection on patient outcomes. Expert Review of Pharmacoeconomic Outcomes Research 2010; 10(4):441-451. Palmer HR, Cottreau JM, Garey KG, Hirsch EB, Musick WL, Tam VH, Yeh RF, on behalf of the Houston Infectious Diseases Network. Significant publications on infectious diseases pharmacotherapy in 2009. American Journal of Health-System Pharmacy 2010;67(15): e34-42. Hirsch EB, Tam VH. Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infections. Journal of Antimicrobial Chemotherapy 2010; 65(6):1119-1125.

2009

Kuper K, Hirsch EB, Tam VH, on behalf of the Houston Infectious Diseases Network. Significant publications on infectious diseases pharmacotherapy in 2008. American Journal of Health-System Pharmacy 2009; 66(19): 1726-1734. Book chapters / contributions

Antiparasitic agents, Chapter 34. Clinical significance and scenario. In: Foye’s Principles of Medicinal Chemistry, 7th edition. Lippincott Williams and Wilkins, WoltersKluwer Health. Copyright 2013.

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Presentations Invited speaker - National 2012

Gram-negative infections and emergence of resistance: is one drug enough? Presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting, Las Vegas, NV. December 4, 2012.

Invited speaker – Regional / local 2014

Management of Gram-negative infections. Presented at Cubist Pharmaceuticals for the post-doctoral fellowship program. Lexington, MA. July 10, 2014.

2012

Resistant Enterobacteriaceae infections: have we lost the battle? Presented at the The Council of Boston Teaching Hospitals and Northeastern University School of Pharmacy: Pharmacy Grand Rounds, Boston, MA. January 9, 2013.

2012

Strategies for management of resistant Gram-negative infections in the ICU. The 9th Annual Critical Care Symposium, Boston, MA. May 8, 2012.

Refereed Conference Presentations - International 2012

Tam VH, Hirsch EB, Lasco TM, Chang KT, Gentry LO, Palmer HR. Correlation of hospital carbapenem consumption and resistance trends in Gram-negative bacteria. To be presented as an oral presentation at the 12th Asian Conference on Clinical Pharmacy. Hong Kong SAR, China, July 2012. Hirsch EB, Guo B, Chang KT, Cao H, Ledesma KR, Singh M, Tam VH. Assessment of antimicrobial combinations for KPC-producing Klebsiella pneumoniae infections. Accepted abstract, Poster Presentation, 22nd European Conference on Clinical Microbiology and Infectious Diseases. London, UK, March 2012.

2011

Hirsch EB, Ledesma KR, Chang KT, Schwartz MS, Motyl MR, Tam VH. Combined activity of MK-7655 and imipenem against carbapenem resistant Pseudomonas aeruginosa. Accepted abstract, Poster Presentation, 21st European Conference on Clinical Microbiology and Infectious Diseases / 27th International Congress of Chemotherapy. Milan, Italy, May 2011.

Refereed Conference Presentations - National 2014

Lee KC, McCoy C, Hirsch EB, Snyder GM, Mahoney MV. The impact of high-dose versus low-dose sulfamethoxazole-trimethoprim in the treatment of Stenotrophomonas

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maltophilia pneumonia. Accepted abstract, Poster Presentation, 49th ASHP Midyear Clinical Meeting. Anaheim, CA, December 2014. Hirsch EB, Raux BR, Zucchi PC, Kim Y, McCoy C, Wright SB, Eliopoulos GM. Activity of fosfomycin against contemporary urinary pathogens collected from a Boston teaching hospital. Accepted abstract, Poster Presentation, 54th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC, September 2014. Jonchhe S, Giancola S, Golik Mahoney MV, Qian Q, McCoy C, Snyder S, Hirsch EB. Outcomes of carbapenem beta-lactam (CBL) versus non-carbapenem beta-lactam (NCBL) treatment for third-generation cephalosporin-resistant (3GCR) Enterobacteriaceae bloodstream infections (BSI). Accepted abstract, Poster Presentation, 54th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC, September 2014. Aitken SL, Altshuler J, Guervil DJ, Hirsch EB, Ostrosky-Zeichner LL, Ericsson CD, Tam VH. Cefepime free minimum concentration (fCmin) to minimum inhibitory concentration (MIC) ratio predicts clinical failure in patients with Gram-negative bacterial pneumonia. Accepted abstract, Poster Presentation, 54th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC, September 2014. 2013

Dziuba K, Golik Mahoney MV, McCoy C, Hirsch EB. Daptomycin versus linezolid for the treatment of vancomycin-resistant enterococcal urinary tract infections. Accepted abstract, Poster Presentation, 48th ASHP Midyear Clinical Meeting. Orlando, FL, December 2013. Giancola S, McCoy C, Golik Mahoney M, Hirsch EB. Patient characteristics and antibiotic prescribing patterns of third-generation cephalosporin-resistant (3GCR) Escherichia coli bloodstream infections (BSI). Accepted abstract, Poster Presentation, 48th ASHP Midyear Clinical Meeting. Orlando, FL, December 2013. Jonchhe S, Golik Mahoney M, McCoy C, Hirsch EB. Efficacy of cefepime therapy for treatment of Enterobacteriaceae bloodstream infections (BSI): an evaluation of the revised susceptibility breakpoints. Accepted abstract, Poster Presentation, 48th ASHP Midyear Clinical Meeting. Orlando, FL, December 2013. Hirsch EB, Lancaster JW, Raux B, Mann R, Leonard SN. Surface microbiology of the iPad Tablet computer and the potential to serve as a fomite. Accepted abstract, Poster Presentation, IDWeek. San Francisco, CA, October 2013. Biehle L, Cottreau JM, Thompson DJ, Filipek RL, O’Donnell JN, Lasco TM. McCoy C, Golik Mahoney M, Hirsch EB. Outcomes after carbapenem treatment for Klebsiella bacteremia: a multicenter assessment of the updated susceptibility breakpoints. Accepted abstract, Poster Presentation, 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Denver, CO, September 2013.

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2012

Filipek RL, Thompson DJ, Golik Mahoney MV, McCoy C, Hirsch EB. Clinical experience with oral fosfomycin for urinary tract infections. Accepted abstract, Poster Presentation, 47th American Society of Health System Pharmacists Midyear Clinical Meeting. Las Vegas, NV, December 2012. Hirsch EB, Chang KT, Francoeur D, Ledesma KR, Tam VH, Lasco TM. An evaluation of multiple phenotypic screening methods for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae. Accepted abstract, Poster Presentation, 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA, September 2012. Biehle L, Hirsch EB, Cottreau JM. Outcomes following carbapenem therapy for Klebsiella bacteremia: an assessment of the updated susceptibility breakpoints. Accepted abstract, Poster Presentation, 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA, September 2012. Mordino J, Hirsch EB, Golik Mahoney M. Creatinine phosphokinase (CPK) elevations in patients on daptomycin with or without a statin. Accepted abstract, Poster Presentation, 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, CA, September 2012.

2011 Phe K, Cao H, Cottreau JM, Tam VH, Hirsch EB. Comparison of morbidity and mortality after Klebsiella pneumoniae carbapenemase (KPC)-producing bloodstream infection stratified by level of carbapenem resistance. Accepted abstract, Poster Presentation, 46th American Society of Health System Pharmacists Midyear Clinical Meeting. New Orleans, LA, December 2011. Hirsch EB, Chang KT, Cao H, Tam VH, Lasco TM. Prevalence of Klebsiella pneumoniae carbapenemase (KPC)-harboring Enterobacteriaceae bloodstream isolates at a large tertiary care center. Accepted abstract, Poster Presentation, 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, September 2011. Hirsch EB, Phe K, Cottreau JM, Lasco TM, Tam VH. Clinical outcomes following Klebsiella pneumoniae carbapenemase (KPC)-harboring Enterobacteriaceae bloodstream infections. Accepted abstract, Poster Presentation, 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, September 2011. Bhagunde P, Chang KT, Hirsch EB, Nikolau M, Tam VH. A novel modeling framework to guide optimal dosing of beta-lactamase inhibitors. Accepted abstract, Platform Presentation, 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, September 2011. Cottreau JM, Patel T, Hirsch EB, Caeiro JP, Tam VH. Impact of glycemic control on outcomes of Pseudomonas aeruginosa (PA) bacteremia. Accepted abstract, Poster

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Presentation, 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, September 2011. Tran TT, Palmer HR, Weston JS, Hirsch EB, Shah DN, Cottreau JM, Tam VH, Garey KG. High dose daptomycin (≥ 8 Mg/kg) for the treatment of non-urinary vancomycinresistant enterococcal infections. Accepted abstract, Poster Presentation, 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, September 2011. 2010

Hirsch EB, Chang KT, Lasco TM, Tam VH. Emergence of KPC-producing Klebsiella pneumoniae isolates in the Texas Medical Center (TMC). Accepted abstract, Platform Presentation, 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, September 2010. Hirsch EB, Cottreau JM, Caeiro JP, Johnson ML, Tam VH. Prospective validation of a model to predict mortality following Pseudomonas aeruginosa (PA) bacteremia. Accepted abstract, Poster Presentation, 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, September 2010. Hirsch EB, Ledesma KR, Chang KT, Motyl MR, Tam VH. In vitro activity of MK-7655 in combination with imipenem (IPM) against carbapenem resistant Gram-negative bacteria. Accepted abstract, Poster Presentation, 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, September 2010. Tran TC, Palmer HR, Weston JS, Hirsch EB, Shah DN, Cottreau JM, Tam VH, Garey KW. Evaluation of a daptomycin PK/PD dose optimization protocol. Accepted abstract, Platform Presentation, 50th Interscience Conference on Antimicrobial Agents and Chemotherapy. Boston, MA, September 2010.

2009

Hirsch EB, Neuhauser MM, Dodds Ashley E, Gallagher JC, Hermsen ED, DePestel DD, Ernst EJ. History of the American College of Clinical Pharmacy's infectious diseases practice and research network (ID-PRN). Accepted abstract, Poster Presentation, American College of Clinical Pharmacy Annual Meeting. Anaheim, CA, October 2009. Hirsch EB, Weston JS, Cottreau JM, Garey KW, Tam VH, Palmer HR. An antimicrobial stewardship restriction protocol optimizes the use of daptomycin. Accepted abstract, Poster Presentation, American College of Clinical Pharmacy Annual Meeting. Anaheim, CA, October 2009.

Refereed Conference Presentations – Regional / Local 2014

Jonchhe S, Giancola S, Golik Mahoney MV, Qian Q, McCoy C, Snyder S, Hirsch EB. Outcomes of carbapenem beta-lactam (CBL) versus non-carbapenem beta-lactam (NCBL) treatment for third-generation cephalosporin-resistant (3GCR) Enterobacteriaceae bloodstream infections (BSI). Accepted abstract, Platform Presentation, 33rd Eastern States Conference for Residents and Preceptors. Hershey, PA, May 2014.

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Dziuba K, Golik Mahoney MV, McCoy C, Hirsch EB. Daptomycin versus linezolid for the treatment of vancomycin-resistant enterococcal urinary tract infections. Accepted abstract, Platform Presentation, 33rd Eastern States Conference for Residents and Preceptors. Hershey, PA, May 2014. Raux B, Lancaster JW, Mann R, Leonard SN, Hirsch EB. Surface microbiology of the iPad tablet computer and the potential to serve as a fomite. Accepted abstract, poster presentation, RISE: 2014. Northeastern University. Boston, MA, April 10, 2014. 2013

Sadaka B, Zucchi PC, Lasco TM, Hirsch EB. Antimicrobial activity of various antibiotics against Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria. Presented at Northeastern University Honors Evening. Boston, MA, April 9, 2013.

2012

Mordino J, Hirsch EB, Golik Mahoney M. Creatinine phosphokinase elevations in patients on daptomycin with or without a statin. Accepted abstract, Platform Presentation, 31st Eastern States Conference for Residents and Preceptors. Hershey, PA, May 2012. Biehle, L, Hirsch EB, Cottreau JM. Outcomes following carbapenem therapy for Klebsiella bacteremia: an assessment of the updated susceptibility breakpoints. Accepted abstract, Platform Presentation, Alcalde XXVI: Southwest Leadership Conference for Pharmacy Residents, Fellows, and Preceptors. Dallas, TX, April 2012.

2011

Villamor CB, Singh R, Chang KT, Hirsch EB, Tam VH. Prevalence of hypermutation and mexX over-expression in pan-aminoglycoside resistant Pseudomonas aeruginosa bloodstream isolates. Accepted abstract, Poster Presentation, Texas Society of Healthsystem Pharmacy Annual Seminar. San Antonio, TX, April 2011.

2007

Hirsch EB, Weston JS, Putney D. Incidence of dysrhythmias resulting in cardiac arrest in patients on class III antiarrhythmics and levofloxacin. Accepted abstract, Platform Presentation, Midwest Pharmacy Residents Conference. Omaha, NE, May 8-10, 2007.

GRANTS External Nosocomial pathogen killing capacity of an antimicrobial surface material. Role: Co-Principal investigator (Co-principal investigator: Steven Leonard) Agency: Nitto Denko Technical Corporation Project period: 2/2014-9/2014 Activity of fosfomycin against contemporary urinary pathogens. Role: Principal investigator Agency: Society of Infectious Diseases Pharmacists Project period: 9/2012-9/2014

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Clinical outcomes following tigecycline treatment for KPC-producing Enterobacteriaceae infections: a matched case-control study. Role: Principal investigator Agency: Pfizer Project period: 10/2011-3/2013 Development of a rapid and reliable screening method for detection of Klebsiella pneumoniae carbapenemase (KPC)-producing isolates in SLEH. Role: Co-principal investigator (Co-principal investigator: Todd Lasco) Agency: St. Luke’s Episcopal Hospital’s Roderick D. MacDonald Research Fund Project period: 3/18/2011-3/17/2012 Doripenem combinations against KPC infections. PK/PD Role: Co-investigator (Principal investigator: Vincent Tam) Agency: Ortho-McNeil Janssen Scientific Affairs LLC Project period: 8/2010-8/2011

Internal Multidisciplinary Collaborations for the Detection and Treatment of Resistant Gram-negative Infections Role: Principal investigator Agency: Northeastern University Mutual Mentoring Advancement Program (M2AP) Project period: 10/2014-7/2015 Activity of fosfomycin against contemporary urinary pathogens Role: Principal investigator Student Investigator: Basem Sadaka Agency: Northeastern University Provost Undergraduate Research Award Project period: 10/2012-5/2013 iPads as Fomites in the Clinical Setting Role: Principal investigator Student Investigator: Brian Raux Agency: Northeastern University Provost Undergraduate Research Award Project Period: 10/15/12-4/15/13

TEACHING AND ADVISING Courses taught Northeastern University School of Pharmacy

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Coordinated Fall 2014

Laboratory-based research co-operative – Ann Phung PHMD4970 Jr/Sr Honors Project 1 – Matias Campos PHMD4970 Jr/Sr Honors Project 1 – Brian Raux PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Research elective, 2 students

Summer 2014

PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Clinical, 4 students (4-week rotation)

Spring 2014

Laboratory-based research co-operative – Yisu Kim

Fall 2013

Laboratory-based research co-operative – Brian Raux PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Clinical, 2 students

Summer 2013

PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Clinical, 2 students (4-week rotation) PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Research elective, 1 student

Spring 2013

PHMD4970 Jr/Sr Honors Project 2 – Basem Sadaka

Fall 2012

Laboratory-based research co-operative – Rachael Mann PHMD4970 Jr/Sr Honors Project 1 – Basem Sadaka

Summer 2012

Laboratory-based research co-operative – Jee Eun Choi PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Clinical, 3 students PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Research elective, 2 students

Spring 2012

Laboratory-based research co-operative – Dennis Francoeur PHMD6461 Advanced Professional Practice Experience, Infectious Diseases-Clinical, 2 students Lectured

Fall 2014

PHMD4631 (CDM3): Respiratory Infections (6 hrs), CNS Infections (2 hrs), Urinary tract infections (2 hrs) PHMD4631 (CDM3) Seminar Facilitator (36 hrs), 17 students

Fall 2013

PHMD6254 (CDM4): Respiratory Infections (4 hrs) and CNS Infections (1 hr)

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PHMD (CDM5): Urinary tract infections (1 hr) PHMD6254 (CDM4) Seminar Facilitator (18 hrs), 15 students

Fall 2012

PHMD6254 (CDM4): Respiratory Infections (4 hrs) and CNS Infections (1 hr) PHMD6254 (CDM4) Seminar Facilitator (18 hrs), 13 students

Fall 2011

PHMD6254 (CDM4) Seminar Facilitator (18 hrs), 11 students

Other teaching experience Summer 2014

PHMD6223 Drug Information and Evaluation: mentored the development and writing of drug information papers for 5 students on infectiousdisease-related questions

Summer 2013

PHMD6223 Drug Information and Evaluation: mentored the development and writing of drug information papers for 6 students on infectiousdisease-related questions

Summer 2012

PHMD6223 Drug Information and Evaluation: mentored the development and writing of drug information papers for 3 students on infectiousdisease-related questions

University of Houston College of Pharmacy Coordinated Spring 2011

PHMD6461 Advanced Professional Practice Experience, Infectious Diseases / Clinical outcomes, 2 students

Lectured Summer 2010

Assessment of ID therapy (2 hrs), Antimicrobial-induced kidney and liver damage (2 hrs); ID elective course

Fall 2010

Bone and joint infections (1 hr), Advanced therapeutics course; Facilitation/discussion of ID cases (6 hrs), Therapeutics skills lab

Summer 2009

Assessment of ID therapy (2 hrs), Antimicrobial-induced kidney and liver damage (2 hrs); ID elective course

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Fall 2009

Bone and joint infections (1 hr), Advanced therapeutics course; Facilitation/discussion aminoglycoside pharmacokinetic cases (2 hrs), Therapeutics skills lab

Undergraduate and graduate advising activities

Northeastern University School of Pharmacy Pharmacy residents 2011-2012

Co-directed research project “Outcomes following carbapenem therapy for Klebsiella bacteremia: an assessment of the updated susceptibility breakpoints” for Lauren Biehle, PharmD; PG2 Infectious Diseases resident at University of Houston/Cardinal Health, Houston, TX. Pharmacy research co-operative experiences

Fall 2014 Spring 2014 Fall 2013 Fall 2012 Summer 2012 Spring 2012

Co-funded and directed Ann Phung, Doctor of Pharmacy student, in labbased research co-operative Co-funded and directed Yisu Kim, Doctor of Pharmacy student, in labbased research co-operative Co-funded and directed Brian Raux, Doctor of Pharmacy student, in labbased research co-operative Co-funded and directed Rachael Mann, Doctor of Pharmacy student, in lab-based research co-operative Co-funded and directed Jee Choi, Doctor of Pharmacy student, in labbased research co-operative Co-funded and directed Dennis Francoeur, Doctor of Pharmacy student, in lab-based research co-operative Laboratory research trainees

Sept. 2014-Present May 2014-Present Jan. 2012-Present Jan.-May 2014 June 2013-May 2014

Ann Phung, PharmD student Matias Campos, PharmD student Brian Raux, PharmD student Yisu Kim, PharmD student J. Nicholas O’Donnell, Visiting Research Assistant (NEU 2013 PharmD graduate) Sept.-Dec. 2012 Rachael Mann, PharmD student Sept 2012-May 2013 Basem Sadaka, PharmD student May-August 2012 Jee Eun Choi, PharmD student Jan. 2012-May 2013 Dennis Francoeur, NEU 2013 Behavioral Neuroscience graduate

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Other • •

Actively involved in the portfolio system; met with 7 (4, 1st year and 3, 2nd year) students on an individual basis to discuss their career plans and review their professional portfolio. Have written numerous letters of reference the past few years for students applying to postgraduate programs.

Beth Israel Deaconess Medical Center Pharmacy residents 2014-2015

Co-directed research project “The impact of high-dose versus low-dose sulfamethoxazole-trimethoprim in the treatment of Stenotrophomonas maltophilia pneumonia” for KC Lee, PGY1 resident.

2013-2014

Directed research project “Outcomes of carbapenem beta-lactam versus non-carbapenem beta-lactam treatment for third-generation cephalosporinresistant Enterobacteriaceae bloodstream infections” for Srijana Jonchhe, PGY1 resident. Co-directed research project “Daptomycin versus linezolid for the treatment of vancomycin-resistant enterococcal urinary tract infections” for Kaitlyn Dzuiba, PGY1 resident.

2011-2012

Co-directed research project “Creatinine phosphokinase elevations in patients on daptomycin with or without a statin” for Jason Mordino, PGY1 resident.

SERVICE AND PROFESSIONAL DEVELOPMENT Service to Northeastern University Department of Pharmacy and Health Systems Sciences 2014-Present

Merit Review Committee

School of Pharmacy 2014-Present

ACPE Self-Study: Standards for Faculty and Staff Committee, Standard 26 section leader

2014-Present

Scholarship and Awards Committee, member

2011-2013

Faculty Research, Development, and Mentoring Committee, member

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Beth Israel Deaconess Medical Center 2011-Present

Clinical pharmacist, infectious diseases / antimicrobial stewardship team

2011-Present

Antimicrobial Subcommittee, member

St. Luke’s Episcopal Hospital 2008-2011

Center for Antimicrobial Stewardship and Epidemiology (CASE), member

2010-2011

Education steering committee, member

Service to the profession Reviewer activities 2014-Present 2013-Present 2013-Present 2013-Present 2013-Present 2012-Present 2010-Present 2010-Present 2013

Journal of Antibiotics, manuscript reviewer Antimicrobial Agents and Chemotherapy, manuscript reviewer Annals of Clinical Microbiology and Antimicrobials, manuscript reviewer Journal of Infection and Chemotherapy, manuscript reviewer Journal of Global Antimicrobial Resistance, manuscript reviewer Expert Review of Anti-infective Therapy, manuscript reviewer Journal of Antimicrobial Chemotherapy, manuscript reviewer Diagnostic Microbiology and Infectious Diseases, manuscript reviewer Journal of Health-System Pharmacy Residents

Committee involvement

2014-Present 2013-2014 2013-2014 2011-2012

Society of Infectious Diseases Pharmacists Vice Chair, Annual Report Committee Member, Annual Report Committee Member, Publications Committee Member, Publications Committee

2013-Present

Council of Boston Teaching Hospitals (COBTH) Steering Committee

2012-2013

American College of Clinical Pharmacy, ID-PRN Chair, Recognition and Travel Committee

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Professional Development Membership in professional organizations 2010-Present 2008-Present 2008-Present 2008-Present

International Society of Anti-Infective Pharmacology Society of Infectious Diseases Pharmacists American College of Clinical Pharmacy American Society for Microbiology