Dr. Robert Plunkett Associate Professor of Neurosurgery, SUNY at Buffalo, Buffalo, NY UB Neurosurgery, Inc. 200 Sterling Drive, Suite 300 Orchard Park, NY 14127 716-218-1020 Education:
Doctor of Medicine: Indiana University School of Medicine, Indianapolis, Indiana, 1974-1978 Bachelor of Arts-Biology: Indiana University, Bloomington, Indiana, 1972-1974 Colorado State University, Ft. Collins, Colorado, 1971-1972
Post-Graduate Training:
Surgical Resident: Vanderbilt University Hospital, Department of Surgery, H.W. Scott, M.D., Chairman, 1978-1980 Neurosurgical Research Fellow: Vanderbilt University Hospital, Surgical Research Laboratory, 1980-1981 Neurology Registrar: Institute of Neurological Sciences, Glasgow, Scotland, 1981 Neurosurgical Resident: Vanderbilt University Hospital, Department of Neurosurgery, W.F. Meacham/ G.S. Allen, Chairmen, 1981-1986 Senior Staff Fellow: Surgical Neurology Branch, National Institutes of Health, Bethesda, Maryland, 1986-1990 Gamma Knife Training Course: Authorized Neurosurgeon, Pittsburgh, Pennsylvania, 1999
Boards and Certifications:
Physicians Licensing Examination: Diplomate, 1978 The American Board of Neurosurgery: Diplomate, written exam passed in 1983, oral exam passed in 1989.
Medical Licensure:
Indiana Medical License; February 1978 Tennessee Medical License; July 1980 Maryland Medical License; July 1987 1
New York Medical License; October 1990
Professional Appointments:
Associate Professor of Neurosurgery, SUNY at Buffalo, Buffalo, NY; 1998-present. Clinical Assistant Professor of Neurosurgery, SUNY at Buffalo, Buffalo, NY; 1996-1998 Assistant Professor of Neurosurgery, SUNY at Buffalo, Buffalo, NY; 1990-1996 Tenured Medical Officer-Surgical Neurology Branch, National Institute of Health, Bethesda, Maryland; 1990 Part-time Staff-Department of Neurological Surgery, Walter Reed Army Medical Center, Washington, D.C.; 1988-1990 Research Assistant-Department of Neurosurgery, Wishard Memorial Hospital, Indianapolis, Indiana; May 1978-June 1978 General Practitioner-Hammond Clinic, Hammond, Indiana; March 1978May 1978 Emergency Room Extern-Community Hospital, Indianapolis, Indiana; 1976-1978 Clinical Assistant-Myasthenia Gravis Clinic-Dr. J. Edward Tether, Indianapolis, Indiana; summer 1975
Awards and Honors:
Phi Beta Kappa; 1974 Alpha Omega Alpha; 1977 Surgery Senior Honors-Indiana University School of Medicine; 1978
Peer Reviewed Publications: 1. Glover JL, Bendick PJ, Link WJ, Plunkett RJ: The Plasma Scalpel: A New Thermal Knife. Lasers Surg Med, 2(1): 101-106, 1982. 2. Nylander WA, Plunkett RJ, Hammon JW, Oldfield EH, Meacham WF: Thiopental Modification of Ischemic Spinal Cord Injury in the Dog. Annals of Thoracic Surgery, 33(1): 64-68, 1982.
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3. Oldfield EH, Plunkett RJ, Nylander WA, Meacham WF: Barbiturate Protection in Acute Experimental Spinal Cord Ischemia. J Neurosurg, 56: 511-516, 1982. 4. Plunkett RJ, Weber RJ, Oldfield EH: Stereotactic Implantation of Dispersed Cell Suspensions into Brain: A Systematic Appraisal of Placement and Cell Survival. J Neurosurg, 69: 228-233, 1988. 5. Plunkett RJ, Saris SC, Bankiewicz KS, Ikejiri B, Weber RJ: Implantation of Dispersed Cells into Primate Brain. J Neurosurg, 70: 441-445, 1989. 6. Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Kopin IJ, London WT, Oldfield EH: The Effect of Fetal Mesencephalo Implants on Primate MPTP-induced Parkinsonism: Histochemical and Behavioral Studies. J Neurosurg, 72: 231-244, 1990. 7. Plunkett RJ, Bankiewicz KS, Cummins AC, Miletich RS, Schwartz JP, Oldfield EH: Long-term Evaluation of Hemiparkinsonian Monkeys After Adrenal Autografting or Cavitation Alone. J Neurosurg, 73(6): 1990. 8. Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Kopin IJ, Oldfield EH: The Effects of Fetal NonDopaminergic Implants on Primate MPTP Induced Parkinsonism, Histochemical and Behavioral Studies. J Neurosurg, 74: 97-104, 1991. 9. Bankiewicz KS, Oldfield EH, Plunkett RJ, Schuette WH, Cogan DG, Hogan N, Zuddas A, Koppin IJ: Apparent Unilateral Visual Neglect in MPTP-hemiparkinsonian Monkeys is Due to Delayed Initiation of Motion. Brain Research, 541: 98-102, 1991. 10. Ewing SE, Weber RJ, Zauner A, Plunkett RJ: Functional Recover in Hemiparkinsonian Rats Following Intrastriatal Implantation of Activated Leukocytes. Brain Research, 576: 42-48, 1992. 11. Sheng JG, McShane LM, Plunkett RJ, Cummins AC, Oldfield EH, Kopin IJ, Palmatier MA: Dopaminergic Neuronal Sprouting and Behavioral Recovery in Hemiparkinsonian Rats After Implantation of Amnion Cells. Experimental Neurology, 123: 192-203, 1993. 12. Miletich RS, Comi G, Bankiewicz K, Plunkett RJ, Adams R, DiChiro G, Kopin I 6-[18F] Fluoro-Ldihydroxyphenylalanine Metabolism and Positron Emission Tomography After Catechol-Omethyltransferase Inhibition in Normal and Hemiparkinsonian Monkeys. Brain Research, 626, 113, 1993. 13. Wang J, Bankiewicz KS, Plunkett RJ, Oldfield EH: Intrastriatal Implantation of Interleukin-1: Reduction of Parkinsonism in Rats by Enhancing Neuronal Sprouting from Residual Dopaminergic Neurons in the Ventral Tegmental Area of the Midbrain. J Neurosurg, 80: 484-490, 1994. 14. Miletich RS, Bankiewicz KS, Quarantelli M, Plunkett RJ, Frank J, Kopin IJ, DiChiro G: MRI Detects Acute Degeneration of the Nigrostriatal Dopamine System after MPTP Exposure in Hemiparkinsonian Monkeys. Annals of Neurology, 35(6): 599-697, 1994.
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15. Bankiewicz KS, Palmatier M, Plunkett RJ, Cummins A, Oldfield EH: Reversal of Hemiparkinsonian Syndrome in Non-Human Primates by Amnion Implantation into Caudate Nucleus. J Neurosurg, 81: 869-876, 1994. 16. Langan TJ, Plunkett RJ, Asada H, Kelly K, Kaseloo P: Long-term Production of Neurotrophic Factors by Astrocyte Cultures from Hemiparkinsonian Rat Brain. GLIA, 14: 174-184, 1995. 17. Asada H, Ip NY, Pan L, Razack N, Parfitt MM, Plunkett RJ: Time Course of Ciliary Neurotrophic Factor mRNA Expression in Coincident with the Presence of Protoplasmic Astrocytes in Traumatized Rat Striatum. J Neurosci Research, 40: 22-30, 1995. 18. Asada H, Kaseloo P, Lis A, Petti D, Plunkett RJ: Traumatized Rat Striatum Produces NeuritePromoting and Neurotrophic Activities in vitro. Experimental Neurology, 139: 173-1887, 1996. 19. Kaseloo PA, Lis A, Asada H, Barone TA, Plunkett RJ: In Vitro Assessment of Neurotrophic Activity from the Striatum of Aging Rats. Neuroscience Letters, 218: 157-160, 1996. 20. Barone T, Plunkett RJ, Hohmann P, Overturf P, Ostrow P, Greenberg S: An Experimental Model of Human Leukemic Meningitis in the Nude Rat. Blood, 90(1): 298-305, 1997. 21. Greenberg SJ, Ulmook C, Overturf PM, Glenister N, Robinson TA, Lis A, Hohmann P, Goldman BD, Oseroff AR, Plunkett RJ: Pleiotropic expression of Heterolgous Cytokine/Receptor Genes in HTLV1 Associated Diseases: Candidate TRS for Chimeric Gene Therapy. Leukemia, 11: 79-81, 1997. 22. Plunkett RJ, Ip NY, Asada H, Friedman B, Pan L, Kaseloo PA, Parfitt MM: Trauma-Induced Striatal CNTF and BDNF and mRna in Hemiparkinsonian Rats. Neuroreport, 8: 507-511, 1997. 23. Stiles JD, Ostrow PT, Balos-Miller L, Greenberg SJ, Plunkett RJ, Grand W, Heffner RR: Correlation of Endothelin-1 and Transforming Growth Factor β1 with Malignancy and Vascularity in Human Glioma. J Neuropathology & Exp Neurology, 56(4): 435-439, 1997. 24. Pollina J, Plunkett RJ, Ciesielski MJ, Lis A, Greenberg SJ, Fenstermaker RA: Intratumoral Infusion of Topotecan Prolongs Survival in the Nude Rat Intracranial U87 Human Glioma Model. J. of NeuroOncology, 39: 217-225, 1998. 25. Plunkett RJ, Allison RR, Grand W: Stereotactic Neurosurgical Biopsy is an Underutilized Modality. Neurosurgical Review, 22: 117-120, 1999. 26. Plunkett RJ, Lis A, Barone TA, Fronckowiak MD, Greenberg SJ: Hormonal Effects on Glioblastoma Multiforme in the Nude Rat Model. J Neurosurg, 90: 1072-1077, 1999. 27. McKinley BP, Michalek A, Fenstermaker RA, Plunkett RJ: The Imapct of Age and Gender on the Incidence of Glial Tumors in New York State from 1976-1995. Journal of Neurosurgery, 93(6): 9329, 2000.
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28. Lobel J, MacDonald IJ, Ciesielski MJ, Barone T, Potter WR, Plunkett RJ, Fenstermaker RA, Dougherty TJ. 2-[1-Hexyloxyethyl]-2-devinyl pyropheophororbide-a (HPPH) in a Nude Rat Glioma Model: Implications for Photodynamic Therapy. Lasers in Surgery & Medicine, 29(5): 397-405, 2001. 29. Selkirk SM, Greenberg SJ, Plunkett RJ, Baron TA, Lis A, Overturf PM: Syngeneic Central Nervous System Transplantation of Genetically Transduced Mature, Adult Astrocytes. Gene Therapy, 432443, 2002. 30. Maslov AY, Barone TA, Plunkett RJ, and Pruitt SC: Neural Stem Cell Detection, Characterization and Age Related Changes in the Sub-Ventricular Zone of Mice. J Neuroscience, 24(7): 1726-1733, 2004. 31. Lis A, Barone TA, Pradakar PN, Plunkett RJ, Roth JA: Expression and localization of Different Forms of DMT1 in Normal and Tumor Astroglial Cells. Mol Brain Res, 122(1): 62-70, 2004. 32. Lis A, Ciesieski MJ, Barone TA, Scott BE, Fenstermaker RA, Plunkett RJ: 2-Methoxyestradiol Inhibts Proliferation of Normal and Neoplastic Glial Cells, and Induces Cell Death, InVitro. Cancer Lett, 213(1): 57-65, 2004. 33. Tawk RG, Duffy-Fronckowiak M, Scott BE, Alberico RA, Diaz AZ, Podgorsak MB, Plunkett RJ, Fenstermaker RA: Stereotactic Gamma Knife Surgery for Trigeminal Neuralgia: Detailed Analysis of Treatment Response. J Neurosurg, 102(3): 442-449, 2005. 34. Pan J-J, Chang W-J, Barone TA, Plunkett RJ, Ostrow PT, Greenberg SJ: Increased Expression of TGF-β1 Reduces Tumor Growth of Human U-87 Glioblastoma Cells in Vivo. Cancer Immunology, Immunotherapy, 55: 918-927, 2006. 35. Karampelas I, Alberico RA, Plunkett RJ, Fenstermaker RA: Intratumoral Hemorrhage After Remote Subtotal Microsurgical Resection and Gamma Knife Radiosurgery for Vestibular Schwannoma. Acta Neurochirurgica, (Wien) 149(3): 313-316, 2007. 36. Selkirk SM, Morrow J, Barone T, Hoffer A, Lock J, DeChant A, Mangla S, Plunkett RJ, Miller R: Elevation of Osteopontin Levels in Brain Tumor Cells Reduces Burden and Promotes Survival through the Inhibition of Cell Dispersal. J Neurooncol, 86: 285-296, 2008. 37. Karampelas I, Podgorsak MB, Plunkett RJ, Fenstermaker RA: Subthalamic Nucleus Metastasis Causing Hemichorea-Hemiballism Treated by Gamma Knife Sterotactic Radiosurgery. Acta Neurochir (Wien), 150(4): 395-396, 2008. 38. Fabiano AJ, Doyle C, Plunkett RJ: Distal Baclofen Pump Catheter Migration Associated with FarLateral Paraspinal Surgical Placement. Neuromodulation: Technology at the Interface, 12(2): 130133(4), April 2009 (epub April 21, 2009 . DOI: 10.1111/j. 1525-1403.2009.00207.x.). 39. Barone TA, Gorski JW, Greenberg SJ, Plunkett RJ: Estrogen Increases Survival in an Orthotopic Model of Glioblastoma. J Neurooncol, October 2009; 95(1): 37-48. Epub May 5, 2009.
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40. Fabiano AJ, Plunkett RJ, Gibbons KJ: Diagnosis of Facial Nerve Schwannoma by Magnetic Resonance Imaging Enhancement of the Geniculate Ganglion. Arch Neural, 67:112-113, January 2010. 41. Gottlieb PA, Barone T, Sachs F, Plunkett R: Neurite Outgrowth from PC12 Cells is Enhanced by an Inhibitor of Mechanical Channels. Neurosci Lett, 481(2): 115-119, 2010. 42. Strojnik T, Kavalar R, Barone TA, Plunkett RJ: Experimental Model and Immunohistochemical Comparison of U87 Human Glioblastoma Cell Xenografts on the Chicken Chorioallantoic Membrane and in Rat Brains. Anticancer Research, 30(12): 2010. 43. Fabiano AJ, Plunkett RJ: Approach for Tunneling the Lead in Deep Brain Stimulation: Technical Note. J Neurosurg, 112:1277-1278, June 1010 (epub July 24, 2009, doi 10.3171/2009.6JNS09554). 44. Erwin A, Gudesblatt M, Bethoux F, Bennett SE, Koelbel S, Plunkett R, Sadiq S, Stevenson VL, Thomas AM, Tornatore C, Zaffaroni M, Hughes M: Intrathecal Baclofen in Multiple Sclerosis: Too Little, Too Late? Multiple Scler. 2011;17(5):623-629. 45. Fabiano AJ, Hoppenot R, Plunkett RJ: Heroin-inhalation-induced Cerebellar Leukoencehalopathy. Accepted for publication in Chirurgia on February 29, 2012. Non-Peer Reviewed Publications: 1. Bankiewicz K, Plunkett RJ, Kopin IJ, Jacobowitz DM, London WT, Oldfield EH: Transient Behavioral Recovery in Hemiparkinsonian Primates After Adrenal Medullary Allografts. Progress in Brain Research, Volume IV, Elsevier Science Publishers, April 1988. 2. Miletich RS, Baniewkicz KS, Plunkett RJ: Fetal Brain Grafts and Parkinson’s Disease. Science, Vol. 250:1434-1435, 1990. 3. Kopin, IJ, Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Oldfield EH: Tissue Implants in Treatment of Parkinsonian Syndromes in Animals and Implications for Use of Tissue Implants in Humans. Adv Neurol 60:707-714, 1993.
Conference Proceedings: 1. Plunkett RJ, Oldfield EH, Nylander WA, Meacham WF: Barbiturate Modification of Spinal Cord Ischemia in the Rabbit Model. Scientific Manuscript of the 50th Annual Meeting of the American Association of Neurological Surgeons, 1981. 2. Plunkett RJ, Nylander WA, Collins JC, Hammon JW, Meacham WF: Mechanism of Thiopental Protection in Spinal Cord Ischemia. The Surgical Forum, Volume XXXII, 1981.
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3. Blumenkopf B, Lipman JJ, Plunkett RJ: Objective Assessment of the Nocioceptive Sensibility and Deficits Associated with Radiculopathy Using the Heat Beam Dolorimeter. Pain, (Supplement 4) page 510, 1987. 4. Kopin KJ, Bankiewica KS, Plunkett RJ, Porrino L, Jacobowitz DM, LondonWT, Oldfield EH: Recent Advances in Dopaminergic Implants. Progress in Parkinson Research, Chapter 26, Plenum Publishing Corporation, 1988. 5. Wang J, Bankiewicz KS, Plunkett RJ, Sheng JG, Jacobowitz DM. Transplantation of Microglia Reduces Experimental Parkinsonism in Rats. Proceedings of “Intracerebral Transplantation in Movement Disorders”, Lund, Sweden, June 20-22, 1990. 6. Greenberg SJ, Choi U, Overturf PM, Glenister N, Robinson TA, Lis A, Hohmann P, Goldman BD, Oseroff AR, Plunkett RJ: Pleiotrophic Expression of Heterologous Cytokine/Receptor Genes in HTLV-1 Associated Diseases: Candidate TRS for Chimeric Gene Therapy. Proceedings of The XVII Symposium of the International Association for the Comparative Research on Leukemia and Related Diseases on Leukemia and Lymphoma/Pathogenesis and Treatment/Molecular Aspects, Kyoto, Japan, October 20-November 3, 1995. Leukemia, 11(3) 79-81, 1997. 7. Morrow JT, Barone TA, Plunkett RJ, Greenberg SJ: Human Peripheral Blood Stem Cells Implanted into a Nude Rat Human Glioblastoma Model. Tenth Annual Meeting of the American Society for Neural Transplantation and Repair, Clearwater, FL, May 2003; Experimental Neurology 181:84-112, 2003. 8. Piccioni DE, Barone TA, Varma R, Morrow J, Plunkett RJ, Ostrow P, Greenberg S: Reversible Interferon-Beta Induced Cell Cycle Arrest of Astoglial Tumors. American Academy of Neurology, Denver, CO, 2003; Neurology 2003:60 (Suppl1) A21.
Abstracts: 1. Nylander WA, Plunkett RJ, Hammon JW, Oldfield EH, Meacham WF: Thiopental Modification of Ischemic Spinal Cord Injury in the Dog: Society of Thoracic Surgeons, Los Angeles, CA. January 26-28, 1981. 2. Plunkett RJ, Oldfield EH, Nylander WA, Meacham WF: Barbiturate Modification of Spinal Cord ischemia in the Rabbit Model: American Association of Neurological Surgeons, Boston, MA. April 5-9, 1981. 3. Plunkett RJ, Nylander WA, Collins JC, Hammon JW, Meacham WF: Mechanism of Thiopental Protection in Spinal Cord Ischemia: American College of Surgeons, Surgical Forum, San Francisco, CA. October, 1981. 4. Plunkett RJ, McKana JA, Cobb CA: Endothelial Changes in Rabbit Carotid Microsurgical Anastomoses (Honorable Mention Resident’s Award) Southern Neurosurgical Society, White Sulphur Springs, West Virginia. March 10-13,1982. 7
5. Blumenkopf B, Lipman J, Plunkett RJ: Objective Assessment of the Nocioceptive Sensibility and Deficits Associated with Radiculopathy using the Head Beam Dolorimeter. Presented at the Joint Section on Spinal Disorders of the AANS and CNS, Boca Raton, FL. January 14-17, 1987. 6. Johnson L, Plunkett RJ, Morris JA: All Terrain Vehicles: Lethal to Children and Adolescents. Presented as part of testimony before the Senate Consumer Sub Committee of the Committee of Commerce, Science and Transportation, Washington, D.C.. May 13, 1987. 7. Plunkett RJ, Weber RJ, Oldfield EH: Stereotactic Implantation of Dispersed Cell Suspensions into Brain: A Critical Appraisal of Placement and Cell Survival. Presented at the Annual Meeting of the American Association of neurological Surgeons, Dallas, TX. May 3-7, 1987. 8. Bankiewicz KS, Oldfield EH, Plunkett RJ, Vaidya U, London WH, Jacobowitz DM, Kopin IJ: Fetal Mesencephalic Implants in MPTP-Treated Monkeys: Creation of Hemiparkinsonism in a Full Parkinsoniam Animal. Presented at the Sixth International Catecholamine Symposium, Jerusalem, Israel. June 14-19, 1987. 9. Bankeiwicz KS, Plunkett RJ, Kopin IJ, Oldfield EH: Adrenal Medulla Allograft Implants Produce Transient Behavioral Recovery in Hemiparkinsonian Monkeys. Presented at the Schmitt Symposium, Rochester, NY. June 30-July 3, 1987. 10. Bankiewicz KS, Plunkett RJ, Kopin IJ, Jacobowitz D, London WT, Oldfield EH: Fetal Mesencephalic Graft Induced Hemiparkinsonism in an MPTP-Parkinsonian Monkey. Presented at the Annual Meeting of the Congress of Neurological Surgeons, Baltimore, MD. October 2429, 1987. 11. Bankiewicz KS, Jacobowitz DM, Plunkett RJ, Oldfield EH, Kopin IJ: Injury-induced Sprouting into the Caudate Nucleus after Solid Tissue Implantation in MPTP-Induced Parkinsonian Monkeys. Presented at the 1987 Meeting of the Society for Neuroscience, New Orleans, LA. Novmeber 17-20, 1987. 12. Miletich RS, Bankiewicz KS, Plunkett RJ, Finn R, Jacobs G, Baldwin P, Adams MS, Kopin I, DiChiro G, Oldfield EH: L-[18F]-6-Fluodopa PET Imaging of Catecholaminergic tissue Implants in HemiParkinsonian Monkeys. Presented at the 40th Annual Meeting of the American Academy of Neurology, Cincinnati, OH. April 19-21, 1988. 13. Plunkett RJ, Saris SC, Bankiewicz KS, Weber RJ, Oldfield EH: Reliable Method to Implant Dispersed Cells into Primate Brain. Presented at the American Association of Neurological Surgeons Annual Meeting, Toronto, Ontario. April 24-28, 1988. 14. Plunkett RJ, Bankiewicz KS, Jacobowitz DM, Kopin IJ, Oldfield EH: Transient Improvement After Adrenal Medullary Implants in Hemiparkinsonian Primates. Presented at the American Association of Neurological Surgeons Annual Meeting, Toronto, Ontario. April 24-28, 1988.
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15. Bankiewicz KS, Porrino L, Palombo EJ, Plunkett RJ, Kopin IJ, Oldfield EH: Local Cerebral Glucose Utilization in MPTP Parkinsonian Monkeys Correlates with Functional Recovery after Fetal Mesencephalic and Adrenal Medulla Allografts. Presented at the American Association of Neurological Surgeons Annual Meeting, Toronto, Ontario. April 24-28, 1988. 16. Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Kopin IJ, Perese DA, Oldfield EH: Sprouting of Host Dopaminergic Fibers into the Caudate Nucleus after Solid Tissue Implantation or Injury in MPTPInduced Parkinsonian Monkeys. Presented at the American Association of Neurological Surgeons Annual Meeting, Toronto, Ontario. April 24-28, 1988. 17. Perese DA, Bankiewicz KS, Plunkett RJ, Ullman J, Oldfield EH: Fiber Sprouting from Host Dopaminergic Neurons in Parkinsonian Rat Model. Presented at the American Association of Neurological Surgeons Annual Meeting, Toronto, Ontario. April 24-28, 1988. 18. Plunkett RJ, Miletich RS, Bankiewicz K, Finn R, Oldfield EH: Positron Emission Tomography with L-[18F]-6-Fluorodopa in Hemiparkinsonian Monkeys Receiving Dopaminergic Tissue Implants. Presented at the American Association of Neurological Surgeons Annual Meeting, Toronto, Ontario. April 24-28, 1988. 19. Kopin IJ, Zuddas A, Weise V, Plunkett RJ, Oldfield EH, Bankiewicz KS: Dopamine and Tyrosine Hydroxylase levels in the Cortical and Subcortical Areas in the MPTP-Parkinsonian Monkeys. Presented at the 1988 Meeting of the Society for Neuroscience, November 13-18, 1988. 20. Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Kopin IJ, Cummins A, Oldfield EH: Implant Induced Catecholaminergic Sprouting in MPTP Parkinsonian Monkeys: Behavioral and Histochemical Studies. Presented at the 1988 Meeting of the Society for Neuroscience, November 13-18, 1988. 21. Miletich RS, Bankiewicz KS, Plunkett RJ, Alger RJ, Brunetti A, Frank J, DiChiro G, Oldfield EH: Magnetic Resonance Imaging of Blood Brain Barrier Disrupture after Catecholaminergic Implants to the Caudate Nucleus of Hemiparkinsonian Monkeys. Presented at the 1988 Meeting of the Society for Neuroscience, November 13-18, 1988. 22. Palmatier MA, Plunkett RJ, Bankiewicz KS, Cummins AC, Kopin IJ: Neurite-promoting Activity from the Brain of MPTP-Treated Monkeys with and without Surgical Lesions. Presented at the Society for Neuroscience Annual Meeting, Toronto, Ontario. November 13-18, 1988. 23. Plunkett RJ, Bankiewicz KS, Jacobowitz DM, Kopin IJ, Cummins AC, Oldfield EH: Immunohistochemistry of Adrenal Autografted and Cavitated Hemiparkinsonian Monkeys. Presented at the Society for the Neuroscience Annual Meeting, Toronto, Ontario. November 13-1/, 1988.
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24. Morgan JK, Plunkett RJ, Palmatier MA, Oldfield EH: Effect of Concentrated Antibiotic Solution on Survival of the Rat Fetal Dopaminergic Neurons. Presented at the Society for the Neuroscience Annual Meeting. November 13-18, 1988. 25. Plunkett RJ, Bankiewicz KS, Miletich RS, Schwartz J, Cummins A, Oldfield EH: Long-term Evaluation of the Hemiparkinsonian Monkeys after Adrenal Autografting or Cavitation Alone. Presented at the American Association of Neurological Surgeons Annual Meeting, Washington, D.C. April 2-5, 1989. 26. Bankiewicz KS, Skirboll S, Mefford I, Hsaio J, Saunders R, Aigner T, Plunkett RJ, Wang J, Oldfield EH, Jordan K: Microdialysis-A New Tool to Study Implant or Injury-induced Recovery in Monkeys with MPTP-Induced Parkinsonism. Presented at the American Association of Neurological Surgeons Annual Meeting, Washington, D.C. April 2-5, 1989. 27. Cummins AC, Bankiewicz KS, Plunkett RJ, Oldfield EH: Quantification of the Remaining Cells in the Dopaminergic Nuclei of MPTP-Treated Monkeys: A Potential Source of Sprouting Fibers after Tissue Implants. Presented at the American Association of Neurological Surgeons Annual Meeting, Washington, D.C. April 2-5, 1989. 28. Ewing SE, Plunkett RJ, Weber RJ: Functional Recovery in Hemiparkinsonian Rats Following Intracerebral Implantation of Inflammatory Cells. Presented at the American Association of Neurological Surgeons Annual Meeting, Washington, D.C. April 2-5, 1989. 29. McCutcheon I, Gress R, Plunkett RJ, Bankiewicz KS, Oldfield EH: The Local Cellular Immune response to Intracerebral Dopaminergic Allografts in Rhesus Monkeys. Presented at the American Association of Neurological Surgeons Annual Meeting, Washington, D.C. April 2-5, 1989. 30. Palmatier MA, Plunkett RJ, Cummins AC, Kopin IJ: Neurite-Promoting Activity is Found in the Brain of MPTP-Treated Hemiparkinsonian Monkeys. Presented at the Molecular and Cellular Mechanisms of Neuronal Plasticity in Aging and Alzheimer’s Disease, at the National Institute on Aging. May 1-3, 1989. 31. Bankiewicz KS, Plunkett RJ, Kopin IJ, Cummins AC, Oldfield EH: Behavioral Recovery in MPTPHemiparkinsonian Monkeys after Amnion Implatation into the Head of Caudate Nucleus. Presented at the IIIrd International Symposium of Neural Transplantation, Cambridge, England. August 6-11, 1989. 32. Luciano ML, Plunkett RJ, Oldfield EH: Fetal Pituitary Allografts to the Adult Rat Hypothalamus Contain and Secrete Pituitary Hormones at Ten Weeks. Presented at the IIIrd International Symposium on Neural Transplantation, Cambridge, England. August 6-11, 1989. 10
33. McCutcheon I, Gress R, Bankiewicz KS, Oldfield EH, Plunkett RJ: The Local Cellular Repsonse to Focal Brain Trauma in Monkeys. Presented at the American Association of Neurological Surgeons, Nashville, TN. April 28-May 3, 1990. 34. Wang J, Jacobowitz DM, Plunkett RJ, Bankiewicz KS: Recovery in Hemiparkinsonian rats after Intracaudal Implantation of Fetal Microglia. Presented at the American Association of Neurological Surgeons, Nashville, TN. April 28-May 3, 1990. 35. Zauner A, Plunkett RJ, Chow T, Palmatier MA, Ewing SE, Porrino L, Weber RJ: InflammationInduced Recovery of Hemiparkinsonian rats Required both Activated T-Cells and Macrophages. Presented at the American Association of Neurological Surgeons, Nashville, TN. April 28-May3, 1990. 36. Luciano M, Kamilaris T, Johnson E, Plunkett RJ, Oldfield EH: Adrenal Axis Response in Rats with Fetal Pituitary Allografts: Direct Graft Stimulation vs. Host Dependent Activation. Presented at the Endocrine Society, June 1990. 37. Plunkett RJ, Ip N, Parfitt MM, Wiegand SJ: Neurotrophic Factors in Traumatized Rat Striatum. Congress of Neurological Surgeons, Washington, D.C. October 31-November 5, 1992. 38. Asada H, Ip N, Parfitt MM, Plunkett RJ: Temporal Profile of the Cellular Reaction and Expression of Ciliary Neurotrophic Factor Messenger Ribonucleic Acid in Traumatized Rat Striatum. Poster, Congress of Neurological Surgeons 43rd Annual Meeting, 1993. 39. Zakeri A, Plunkett RJ, Parfitt MM: Origin of Regenerating Fibers in Hemiparkinsonian Monkeys Following Surgical Cavitation of the Striatum. Poster, Congress of Neurological Surgeons 43rd Annual Meeting, 1993. 40. Robinson T, Plunkett RJ, Hohmann P, Overturf P, Ostrow P, Greenberg S: Human Leukemic Meningitis: A Model in the Nude Rat. Presented at the Research Society of Neurological Surgeons Annual Meeting, Iowa City, IA. June 1993. 41. Plunkett RJ, Stiles JD, Lis A, Ostrow PT, Balos Miller LL, Winfield J, Greenberg SJ: Identification of Angiographic Growth Factors in Human Glioblastoma In Vitro and in an In Vivo Nude Rat Model. Poster, Congress of Neurological Surgeons Annual Meeting, San Francisco, CA. October 14-19, 1995.
42. Greenberg SJ, Choi U, Overturf PM, Glenister N, Robinson TA, Lis A, Hohmann P, Goldman BD, Oseroff AR, Plunkett RJ: Pleiotropic Expression of Heterologous Cytokine/Receptor Genes in HTLV-I Associated Diseases: Candidate TRS for Chimeric Gene Therapy. Presented at the XVIII Symposium of the International Association for Comparative Research on Leukemia and Related Diseases, Japan, 1995.
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43. Stiles JJ, Greenberg SJ, Ostrow PT, Plunkett RJ, Overturf PM, Robinson TA, Lis A, Choi U: Transformation of In Vivo Malignant Phenotype in Human Gliomas Transduced with Genes Encoding Angiogenic Growth Factors. Presented at the American Academy of Neurology 48th Annual Meeting, San Francisco, CA. March 23-30, 1996. 44. Greenberg SJ, Choi U, Overturf PM, Du TU, Choi Y, Zheng H, Glenister N, Robinson TA, Plunkett RJ, Lis A, Hohmann P: Drug Activation Via Chimeric Promoter-Enzyme Gene Constructs to Treat Leukemic/Lymphomatous Meningitis. Presented at the American Academy of Neurology 48th Annual Meeting, San Francisco, CA. March 23-30, 1996. 45. Goetz CG, Bakay RAE, Fine A, Freed C, Freed W, Markham CH, Olanow CW, Plunkett RJ, Redmond E, Stebbins GT: American Society of Neural Transplantation Registry for Fetal Mesencephalic Implants: Demographic and Baseline Data. Presented at the American Society for Neural Transplantation Third Annual Conference, Sand Key, FL. April 25-27, 1996. 46. Lis A, Pollina J, Robinson TA, Stiles JJ, Greenberg SJ, Plunkett RJ: Sex-Dependent Differences in the Survival of Nude Rats Implanted Intracerebrally with Glioblastoma Cell Line. Presented at the Congress of Neurological Surgeons Annual Meeting, Montreal, Quebec. September 28October 3, 1996. 47. Pollina J, Plunkett RJ, Ciesielski MJ, Lis A, Fenstermaker RA: Intratumoral Infusion of Topotecan Prolongs Survival in the Nude Rat/ U87 Human Glioma Model. Presented at the Congress of Neurological Surgeons Annual Meeting, Montreal, Quebec. September 28-October 3, 1996. 48. Pollina J, Greenberg SJ, Robinson TA, Hohmann P, Plunkett RJ,: Primary Central Nervous System Lymphoma: An Animal Model Using an Intracerebrally Injected Human T Cell Line. Presented at the Congress of Neurological Surgeons Annual Meeting, Montreal, Quebec. September 28-October 3, 1996. 49. Allison RR, Plunkett RJ, Grand W, Vongtama V, Shin KH: Stereotactic Neurosurgical Biopsy is an Underutilized Modality. Presented at the Seventh International Congress on Anti-Cancer Treatment, Paris, France. February 3-6, 1997. 50. Pollina J, Ciesielski M, Lis A, Castiglia G, Greenberg S, Fenstermaker R, Plunkett RJ: Efficacy and Distribution of Intratumoral Topotecan in a Nude Rat Glioma Model and the Rhesus Monkey. American Association for Cancer Research, April 1997. 51. Plunkett RJ, Allison RR, Grand W: Stereotactic Neurosurgical Biopsy is an Underutilized Modality: American Radium Society Annual Meeting, New York City. April 30-May 4, 1997. 52. Lis A, Barone TA, Greenberg SJ, Plunkett RJ: Gender Related Differences in Survival in Nude Rats Implanted Intracerebrally with Human Gliomas. Congress of Neurological Surgeons Annual Meeting. September 27-October 2, 1997.
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53. Withiam-Leitch SA, Barone TA, Lis A, Plunkett RJ, Langan TJ: Neurotrophic Potential of Long Term Adult Astrocytes. Great Lakes Glia Meeting, Spetember 13-15, 1997. 54. Lis A, Barone TA, Ciesielski MJ, Fenstermaker RA, Greenberg SJ, Plunkett RJ: 2-ethoxy-estradiol Blocks Glioma Proliferation, Induces Apoptosis In Vitro and Prolongs Survival in Glioma Bearing Rats. Congress of Neurological Surgeons, New Orleans, LA. October 1997. 55. DeLacure MD, Wang HZ, Fenstermaker RA, Plunkett RJ: The Safety of Acute Perioperative MRI in Microvascular Skull Base Reconstruction Utilizing a Ferromagnetic Microvascular Anastomotic Device. Second International Interdisciplinary Congress of Craniofacial and Skull Base Surgery, Cancun, Mexico. January 1998. North American Skull Base Sociery, Kamuela, Hawaii. February 13-17, 1998. 56. Plunkett RJ, McCarthy B, Barone T, Lis A, Surawicz T, Davis F, Fronckowiak MD: Influence of Gender on Survival of Patients with Glioma; Analysis of the SEER Database. Canadian NeuroOncology Biennial Meeting, Niagara-on-the-Lake, Ontario. May 7-9, 1998. AANS Annual Meeting, Philadelphia, PA. April 25-30, 1998. 57. Rodas RA, Fenstermaker RA, Grand W, Plunkett RJ, Pantano J: Hydroxyura and Concurrent Radiation as Adjuvant Therapy in Recurrent Meningiomas. American Association of Neurolgical Surgeons – Brain Tumor Satellite Symposium, Philadelphia, PA. April 1998. 58. Lis A, Ciesielski MJ, Plunkett RJ: 2-methoxyestradiol Blocks Glioma Proliferation and Induces Apoptosis In Vitro. European Meeting on Glial Cell Function in Health and Disease, Greece 1998. 59. Barone TA, Duncan AM, Plunkett RJ: High Dose Estradiol Benzoate Increases Survival in Nude Rats Implanted Intracerebrally with Human Gliomas. Congress of Neurological Surgeons, Seattle, Washington. October 3-8, 1998. 60. Greenberg SJ, Pan JJ, Plunkett RJ, Barone TA, Spence PM, Choi U, Zhang H, Balos LL, Ostrow PT: Regulation of the Astroglioma Phenotype by the TGF-β1 Ligand/Receptor Signaling Pathway. 1998 American Academy of Neurology Scientific Program. 61. Landi MK, Plunkett RJ: Fluoroscopically-Assisted Laser Guided Facet Denervation. Congress of Neurological Surgeons, 1998. 62. Landi MK, Grand W, Fronckowiak MD, Li V, Plunkett RJ: Central Neurocytoma: An Analysis of the Effects of Surgery and Radiotherapy. A Review of 225 Cases. Congress of Neurological Surgeons, 1998. 63. DeLacure MD, Wang HZ, Fenstermaker RA, Plunkett RJ: The Safety of Acute Perioperative MRI in Microvascular Skull Base Reconstruction Utilizing a Ferromagnetic Microvascular Anastomotic Device. American Society of Reconstructive Microsurgery, Hawaii, Hawaii. January 16-18, 1999.
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64. Lis A, Skierski J, Barone TA, Ciesielski M, Plunkett RJ: 2-Methoxyestradiol Inhibits Proliferation and Induces Apoptosis Independent of P53 Status in Glioma Cells. Society for Neuro-Oncology 4th Annual Meeting, Scottsdale, AZ. November 17-21, 1999. 65. Lobel J, MacDonald I, Ciesielski M, Barone T, Potter W, Plunkett RJ, Fenstermaker R, Dougherty T: 2-[1-Hexyloxyethyl]-2-Devinyl Pyropheophorbide-a (HPPH) Pharmacokinetics in a Nude Rat Glioma Model: Implications for Photodynamic Therapy. Society for Neuro-Oncology, Scottsdale, AZ. November 1999. 66. Proulx GM, Plunkett RJ, Lee RJ, Jia C, Mechtler L, Podgorsak MB, Fenstermaker RA: Stereotactic Radiosurgery for Malignant Gliomas. The Radium Society, 1999. 67. Laws ER, Anderson F, Asher A, Bernstein M, Hartman L, Sloan A, Phillips L, Singleton C, and the *Glioma Outcomes Investigators: Treatment of Malignant Glioma: Patterns of Care as Reflected by the Glioma Outcomes Project, American Association of Neurological Surgeons, San Francisco, Ca. April 2000. 68. Lillehei KO, Anderson F, Bernstein M, Sawaya R, Phillips L, Singleton C and the *Glioma Outcomes Investigators: Perioperative Complications of Biopsy and Craniotomy in Treatment og Malignant Gliomas: Data from the Glioma Outcomes Project. American Association of Neurological Surgeons, San Francisco, CA. April 2000. 69. Anderson F, Hochberg F, Meyers C, Rock J, Phillips L, Singleton C, and the *Glioma Outcomes Investigators: Functional Status Following Surgery for High-Grade Glioma: Preliminary Results from the Glioma Outcomes Project. American Association of Neurological Surgeons, San Francisco, CA. April 2000. 70. Asher A, Stolzenbach K, Barker F, Limentani S, Laws E, Phillips L, and the *Glioma Outcomes Investigators: Differences Between Community and Academic Medical Centers in the Care of Patients Undergoing Surgery for Glioma: Findings from the Glioma Outcomes Project, Society for Neuro-Oncology, Chicago, IL. November 2000. 71. Phillips L, Meyers C, Litofsky NS, and the *Glioma Outcomes Investigators: Physician and Surgeon Evaluated Depression in the Glioma Outcomes Project: Concordance, Discordance and Conclusions, Society for Neuro-Oncology, Chicago, IL. November 2000. 72. Maslov A, Barone TA, Plunkett RJ, and Pruitt S: Utility of Mcm2 Expression for Identification of Neural Stem Cells, Arthur M. Sackler Colloquia of the National Academy of Sciences, “Regenerative Medicine”. October 18-20, 2002. 73. Wong MY, Plunkett RJ: The Paraspinous, Transmuscular Approach for Placement of the Inrathecal Catheter for a Baclofen Pump. American Society for Stereotactic and Functional Neurosurgery, “Spasticity”, New York, NY. May 18-21, 2003.
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74. Piccioni DE, Barone T, Varma R, Morrow J, Plunkett RJ, Ostrow P, Greenberg S: Reversible Interferon-Beta Induced Cell Cycle Arrest of Astoglial Tumors. American Academy of Neurology, Honolulu, HI. April 2003; in Neurology 60 (suppl 1): A21, April 2003. 75. Morrow JT, Barone TA, Plunkett RJ, Greenberg SJ: Human Peripheral Blood Stem Cells Implanted into a Nude Rat Human Glioblastoma Model. Tenth Annual Meeting of the American Society for Neural Transplantation and Repair, Clearwater, FL. May 2003; in Experimental Neurology 181: 84-112, 2003. 76. Piccioni D, Barone TA, Featherstone A, Ostrow P, Greenberg S, Plunkett RJ: Retrovirally Transduced Adult Rat Astrocytes Modulate Tumor Proliferation through Transgene Expression of Interferon-Beta. Eleventh Annual Meeting of the American Society for Neural Transplantation and Repair, Clearwater, FL. May 2004; in Experimental Neurology 187: 203-227, 2004. 77. Cerinca G, deBoer S, Plunkett RJ, Podgorsak MB: A Geometrical Method for Lesion Placement in Radiosurgery of Functional Brain Disorders. Bi-Annual Meeting of the Upstate Chapter of the AAPM, Syracuse, NY. November 12, 2004. 78. Fabiano A, Doyle C, Trinidad K, Plunkett RJ: Distal Baclofen Pump and Catheter Migration Associated with Far Lateral Paraspinal Surgical Placement. Poster at Congress of Neurological Surgeons Annual Meeting. October 7-12, 2006. 79. Barone TA, Gottlieb PA, Murphy YK, Sachs F, Plunkett RJ: A Peptide from Tarantula Venom Enhances NGF-Induced Neurite Production in Dopaminergic PC 12 Cells; in Cell Transplantation 17(4): 461, 2008. 80. Plunkett RJ, Prasad D, Snyder KV, Kuettel G, Fabiano AJ: Ommaya Resovoir Drainage and Gamma Knife Radiosurgery for Cystic Metastases. 14th International Meeting of the Leksell Gamma Knife Society, Quebec City, Canada, 2008. 81. Walsh M, Plunkett RJ, Sablauer A, Fenstermaker R, Prasad D: Gamma Knife Radiosurgery for Cerebral Metastases from Radioresistant Primaries: Renal Cell Cancer and Melanoma: Imaging and Clinical Outcomes. 14th International Meeting of the Leksell Gamma Knife Society, Quebec City, Canada, June 2008. 82. Dad L, Prasad D, Plunkett R, Fenstermaker R, deBoer S, and Podgorsak M: Gamma knife surgery for meningiomas. 14th International Meeting of the Leksell Gamma Knife Society, Quebec City, Canada, June 2008. 83. Sablauer A, Prasad D, Fenstermaker R, Plunkett R, and Podgorsak MB: A unified computer database system for direct connectivity to Gamma Plan for data mining and analysis. 14th International Meeting of the Leksell Gamma Knife Society, Quebec City,Canada, June 2008. 84. Walsh M, Prasad D, Plunkett R, Fenstermaker R, deBoer S and Podgorsak M: Gamma Knife surgery for metastatic Renal cancer and Melanoma to the brain. 14th International Meeting of the Leksell Gamma Knife Society, Quebec City, Canada, June 2008. 15
85. Fabiano AJ, Hojnacki DW, Weigel P, Fenstermaker RA, Plunkett RJ: Increased Incidence of Vestibular Schwannomas in Multiple Sclerosis Patients. Annual Meeting of the American Association of Neurological Surgeons, San Diego, CA, 2009. 86. Fabiano AJ, Doyle C, Plunkett RJ: Treatment of Post-Herpetic Neuralgia with Intrathecal Narcotic Administration. Annual Meeting of the American Association of Neurological Surgeons, San Diego, CA, 2009. Media Presentations: 1. Dr. Plunkett and Mr. Holtz, a patient with a Deep Brain Stimulator, appeared on A.M. Buffalo to highlight this novel treatment for Parkinson’s Disease, January 2002. 2. Medical Matters TV Show aired on Time Warner Cable Network for over a 3 month time span. Pat Weigel, R.N. and Dr. Robert Plunkett gave an overview of Parkinson’s Disease and what our community has available to families and patients as treatment and support. July 25, 2008. Invited Presentations (Regional): 1.
Practical Neuroanatomy: A Neurosurgeon’s Prospective. This presentation was given to the Freshman Anatomy Course at Vanderbilt University School of Medicine, Nashville, Tennessee. May 1984- 1986.
2. Brain Implants in MPTP-Induced Parkinsonian Primates. This presentation was given at NINDS Grand Rounds, National Institute of Health, Bethsada, Maryland. September 25, 1987. 3. Dopaminergic Implants in MPTP-Induced Parkinsonian Primates. This presentation was given at the Neurosurgery Grand Rounds at Georgetown University Hospital, Washington, D.C. October 2, 1987. 4. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurology Grand Rounds at the Medical College of Virginia, Richmond, Virginia. March 2, 1988. 5. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurology Grand Rounds at the Pennsylvania State College of Medicine, Hershey, Pennsylvania. March 8, 1988. 6. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurology Grand Rounds at theWest Virginia University School of Medicine, Morgantown, West Virginia. April 7, 1988. 7. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurology Grand Rounds at the East Virginia School of Medicine, Norfolk, Virginia. May 17, 1988.
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8. Adrenal Autografting for Parkinsonism: Experimental and Clinical Perspectives. This presentation was given at the Neurology Grand Rounds at Georgetown University Hospital, Washington, D.C. June 8, 1988. 9. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurosurgery Weekly Conference at John’s Hopkins University Hospital, Baltimore, Maryland. June 8, 1988. 10. Surgical Look at Parkinson’s Disease. This presentation was given at the Suburban Hospital Grand Rounds, Bethesda, Maryland. August 3, 1988. 11. Brain Grafting for Parkinsonism: Experimental and Clinical Perspectives. This presentation was given at the Neurology/Neurosurgery Grand Rounds at the Walter Reed Army Medical Center, Washington, D.C. November 7, 1988. 12. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurology Grand Rounds at the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania. March 16, 1989. 13. Concussion and Head Injury. This presentation was given at the monthly health seminar at the National Institute of Standards and Technology, Gaithersburg, Maryland. March 23, 1989. 14. Tissue Implantation in Parkinsonian Primates. This presentation was given at the Neurosurgery Grand Rounds at the University of Kentucky Medical Center, Lexington, Kentucky. March 30, 1989. 15. Neural Transplantation: An Update. This presentation was given at the Academic Neurosciences Meeting-Institute of Neurological Sciences, Glasgow, Scotland. August 4, 1989. 16. Spinal Cord Lesions Posing Challenges: Spinal Dural Arteriovenous Fistulas. This presentation was given at the 9th International Congress of Neurological Surgery, New Delhi, India. October 12, 1989. (Panelist) 17. Mechanisms of Functional Recovery after Brain Implantation in Subhuman Primates. This presentation was given at the XIVth International Symposium of the Fulton Society-The Neurobiology of Brain Implants, New Delhi, India. October 27, 1989. 18. Tissue Implantation: From Dopamine to Trophic Factors, and Parkinsonism: Is it a Surgical Disease? These were presented at the SUNY Health Science Center at Syracuse as a Visiting Professor. April 17, 1991. 19. Tissue Implantation for Parkinsonism-From Dopamine to Trophic Factors. This presentation was given at Henry Ford Hospital as a Visiting Professor, Detroit, Michigan. June 7, 1991. 20. Surgical Therapy for Parkinsonism. This presentation was given at Neurology Grand Rounds at Buffalo General Hospital, Buffalo, New York. May 14, 1992.
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21. Think First Head and Spinal Cord Injury Prevention Program. This presentation was given at WNY Science and Exposition Day at SUNY Buffalo, Buffalo, New York. May 20, 1992. 22. Pathology of Low Back Pain, and Role of the Pain Clinic in the Treatment of Low Back Pain. This presentation was given at “Low Back Pain and the Primary Care Physician”, sponsored by SUNY Buffalo at the Radison Hotel, Buffalo, New York. January 23, 1993. 23. Neuro-Stimulation. This presentation was given at Neurology Grand Rounds at Buffalo General Hospital, Buffalo, New York. February 18, 1993. 24. Subarachnoid Hemorrhage. This presentation was given at the Department of Medicine in the VA Medical Center, Buffalo, New York. August 23, 1993. 25. Brain Tumors. This presentation was given at the Department of Medicine at the VA Medical Center, Buffalo, New York. November 8, 1993. 26. Parkinsonism-Is it a surgical problem? This presentation was given at Surgical Grand Rounds at William Beaumont Hospital, Royal Oak, Michigan. January 11, 1994. 27. Spinal Cord Compression. This presentation was given at the Department of Medicine at the VA Medical Center, Buffalo, New York. March 14, 1994. 28. Morbidity and Mortality. This presentation was given at the Department of Medicine at the VA Medical Center, Buffalo, New York. September 15, 1994. 29. Evaluation of Patient with Disc Disease. This presentation was given at the Department of Medicine at the VA Medical Center, Buffalo, New York. March 16, 1995. 30. Stereotactic Biopsy. This presentation was given to the Department of Nursing at Buffalo General Hospital, Buffalo, New York. April 5, 1995. 31. Neural Transplantation, from Lab to Clinic (and back). This presentation was given to the Department of Neurosurgery at George Washington University, Washington, D.C. May 24, 1995. 32. Dementia Information for Patients and Families and Surgical Treatment for Parkinson’s Disease. This presentation was given as Caregiver information for patients and families at the VA Medical Center, Buffalo, New York. June 13, 1995. 33. Pallidotomy. This presentation was given at the Neurology Grand Rounds at Buffalo General Hospital, Buffalo, New York. December 21, 1995. 34. The Pain Clinic and Chronic Pain Management. These presentations were given at Pathology of Low Back Pain, sponsored by the State University of New York, Buffalo, New York. January 13, 1996.
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35. Stereotaxis-Present and Future. This presentation was given at the Radiation Oncology Grand Rounds at Buffalo General Hospital, Buffalo, New York. January 29, 1996. 36. Frameless Stereotaxy. This presentation was given at New Horizons in Neuroscience Nursing, sponsored by the American Association of Neuroscience Nurses, Buffalo Hilton, Buffalo, New York. June 14, 1996. 37. Cavernomas. This presentation was given at The Brain Microvasculature: Clinical Applications for Neurologists and Neurosurgeons at the State University of New York at Buffalo, Buffalo, New York. May 3-4, 1997. 38. Potential of Autologous Astrocytes for Brain Repair. This presentation was given at the 1997 Rose and Al Pastor Lecture Series, Buffalo, New York. September 18-19, 1997. 39. Gender and Glioma – A New Prognostic Factor? This presentation was given at the Surgical Neurology Branch Weekly Conference at the National Institute of Health, Bethesda, Maryland. October 14, 1997. 40. Intrathecal Baclofen: MS and Beyond. This presentation was given at the Neurology Grand Rounds at Buffalo General Hospital, Buffalo, New York. January 8, 1998. 41. Sickle Cell, Lower Back Pain and Tuberculosis. This presentation was given at the Department of Medicine Grand Rounds at Buffalo General Hospital, Buffalo, New York. January 15, 1998. 42. Brain Tumors, Neurodegenerative Disorders. These presentations were given at the Department of Experimental Pathology on Brain Tumors and Neurodegenerative Disorders as a Graduate Lecture at Roswell Park Cancer Institute. April 1, 1998. 43. Perimesencephalic Hemorrhage. This presentation was given at the Cerebral Small Artery Disease Conference, Sheraton Inn, Buffalo, New York. September 12, 1998. 44. History of Surgical Management of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Conference, Sheraton Inn, Buffalo, New York. November 7, 1998. 45. Chiari Malformations. This presentation was given at the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. December 10, 1998. 46. Parkinson’s Disease Research and New Surgeries. This presentation was given at the Parkinson’s Disease Education Symposium, Sheraton Inn, Buffalo, New York. June 5, 1999. 47. New Treatment Modality for Brain Tumors. This presentation was given to the Department of Surgical Oncology at Roswell Park Cancer Institute, Buffalo, New York. February 23, 2000. 48. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 2000.
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49. Spinal Cord Stimulation. This presentation was given at the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. August 31, 2000. 50. Intrathecal Baclofen for Spasticity. This presentation was given to the Western New York Case Manager Network, Buffalo, New York. October 10, 2000. 51. Primary Brain Tumor. This presentation was given at Roswell Park Cancer Institute, Buffalo, New York. November 6, 2000. 52. Post Operative Craniotomy Care. This presentation was given at Roswell Park Cancer Institute, Buffalo, New York. November 13, 2000. 53. Deep Brain Stimulation for Movement Disorders. This presentation was given at the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. February 1, 2001. 54. Oral and Inrathecal Baclofen. This presentation was given at the Anti-Spasticity Medication Lectures at Buffalo General Hospital, Buffalo, New York. March 16, 2001. 55. Management of Brain Metastases. This presentation was given at Surgical Grand Rounds at Roswell Park Cancer Institute, Buffalo, New York. March 21, 2001. 56. Deep Brain Stimulation. This presentation was given at the Seminar for MRI Society, Buffalo, New York. March 2, 2001. 57. Update on Surgical Treatments for Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 30, 2001. 58. Management of Adult Chiari Malformation. This presentation was given at the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. September 27, 2001. 59. Normal Pressure Hydrocephalus. This presentation was given at the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. December 20, 2001. 60. Neurostimulation for Chronic Lower Extremity Pain. This presentation was given at Sheehan Grand Rounds at Sheehan Memorial Hospital, Buffalo, New York. February 9, 2002. 61. Deep Brain Stimulation of the STN, Parkinson’s Control Therapy Presentation. This presentation was given at the Jones Memorial Health Center, Jamestown, New York. March 11, 2002. 62. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given to the Association of Registered Nurses of Western New York, Buffalo, New York. May 2, 2002.
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63. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the 1st Bosnia and Herzegovina Congress of Neurology; Tuzla, Bosnia and Herzegovina. May 912, 2002. 64. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 2, 2002. 65. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Western New Work Chapter of American Association of Neuroscience Nurses, Amherst, New York. June 5, 2002. 66. An Implantable Drug Delivery System for Intrathecal Treatment of Spasticity or Pain. This presentation was given at the WCA Hospital Grand Rounds, Jamestown, New York. September 18, 2002. 67. What is Gamma Knife and how it is used for Neurological Diseases. This presentation was given at the Western New York Nurse Case Manager Network, Buffalo, New York. October 8, 2002. 68. Intrathecal Baclofen for Spasticity. This presentation was given at Millard Fillmore Gates Hospital to the Physical Therapy and Nursing Departments, Buffalo, New York. February 20, 2003. 69. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at Independent Health, Buffalo, New York. February 25, 2003. 70. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 7, 2003. 71. Spinal Cord Stimulation. This presentation was given at the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. September 18, 2003. 72. Intrathecal Baclofen for Spasticity. This presentation was given at the Chautauqua County Chapter of MS Society, Jamestown, New York. October 10, 2003. 73. Deep Brain Stimulation. This presentation was given at the Niagara County Chapter of the Parkinson’s Wellness Group of Western New York, Inc., Niagara Falls, New York. November 2, 2003. 74. Deep Brain Stimulation. This presentation was given to the Neurology/Neurosurgery Grand Rounds at Buffalo General Hospital, Buffalo, New York. February 26, 2004. 75. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 26, 2004.
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76. Intrathecal Baclofen. This presentation was given at Summer University in Tuzla, Bosnia. July 2004. 77. Deep Brain Stimulation. This presentation was given at Summer University in Tuzla, Bosnia. July 2004. 78. Deep Brain Stimulation. This presentation was given to the State University of New York at Buffalo Neuroscience Graduate Program, Buffalo, New York. February 18, 2005. 79. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 11, 2005. 80. Deep Brain Stimulation for Parkinson’s Disease. This presentation was given at the Department of Internal Medicine Seminar Series at Millard Fillmore Gates Hospital, Buffalo, New York. January 10, 2006. 81. Deep Brain Stimulation for Parkinson’s Disease and Tremor, and Intrathecal Baclofen for Spasticity. These presentations were given at the Western New York nurse Case Manager’s Meeting, Buffalo, New York. April 11, 2006. 82. Deep Brain Stimulation for Parkinson’s Disease. This presentation was given to the Parkinson’s Disease Patient Education Series, Buffalo, New York. April 25, 2006. 83. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. June 11, 2006. 84. Deep Brain Stimulation for Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. May 5, 2007. 85. Deep Brain Stimulation. This presentation was given at the Parkinson’s Disease Education Symposium, Buffalo, New York. April 26, 2008. 86. Gamma Knife Surgery for Meningiomas. This presentation was given at the 14th International Meeting of the Leksell Gamma Knife Society, Montreal, Quebec. May 20, 2008. 87. Deep Brain Stimulation for Parkinson’s Disease and Tremor. This presentation was given at the Medical Grand Rounds at St. Joseph’s Hospital, Buffalo, NY. October 2, 2008. 88. Neuromodulation: Deep Brain Stimulation and Intrathecal Baclofen. This presentation was given at the Nurse Practitioner Association Monthly Meeting, Buffalo, NY. December 3, 2008. 89. Gamma Knife Thalamotomy. This presentation was given at the Neurosurgical Forum, Jacksonville, FL. March 13, 2009.
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90. Deep Brain Stimulation for Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Symposium, Buffalo, NY. May 9, 2009. 91. Treatment of Brain Metastases. This presentation was given to the Department of Neurosurgery, Medical Oncology, Radiation Oncology, Tuzla, Bosnia, November 3, 2009. 92. Radiosurgery. This presentation was given to the Department of Neurosurgery and Radiation Oncology, Tuzla, Bosnia, November 3, 2009. 93. Surgical Treatment of Movement Disorders. This presentation was given to the Department of Neurology, Tuzla, Bosnia, November 4, 2009. 94. Treatment of Brain Metastases and Gamma Knife Thalamotomy. These presentations were given to the 6th year Medical Students, Tuzla, Bosnia, November 4, 2009. 95. Update on Deep Brain Stimulation for Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Symposium, Buffalo, NY. April 24, 2010. 96. Troubleshooting Intrathecal Pump Problems. This presentation was given at the Medtronic Neuromodulation and Pain Northeast Regional Meeting, Buffalo, NY. February 6, 2010. 97. Deep Brain Stimulation – Parkinson’s Disease, Tremor, and New Horizon’s. This presentation was given at the Kaleida Neurosciece Symposium, Niagara Falls, NY. October 1, 2010. 98. Deep Brain Stimulation for Parkinson’s Disease. This presentation was given to the Northtowns Parkinson’s Wellness Group, Buffalo, NY. December 9, 2010. 99. Deep Brain Stimulation for Parkinson’s Disease and Tremor. This presentation was given at the Mercy Hospital Grand Rounds, Buffalo, NY. April 2, 2011. 100. Deep Brain Stimulation for Parkinson’s Disease. This presentation was given at the Parkinson’s Disease Symposium, Buffalo, NY. May 7, 2011. 101. DBS Theory/Application/Indications. This presentation was given at the Comprehensive Education Consortium for Parkinson’s Disease at Roswell Park, Buffalo, NY. June 25, 2011. Invited Presentations (National): 1. Stereotactic Implantation of Dispersed LAK Cells in Rat Brain. This presentation was given at the Meacham Neurosurgical Society Annual Meeting, Destin, Florida. June 18.1987. 2. Brain Grafts in Parkinsonian Monkeys. This presentation was given at the Meacham Neurosurgical Society Annual Meeting, Destin, Florida. June 20, 1987.
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3. Adrenal Autografts for Parkinsonism. This presentation was given at the Meacham Neurosurgical Society Annual Meeting, Nashville, Tennessee. June 2, 1988. 4. Cerebral Grafting for Functional Restoration: Techniques and Observations. This presentation was given at the American Association of Neurological Surgeons Annual Meeting, Washington, D.C. April 4, 1989. 5. Current Status: Adrenal Transplants for Parkinson’s Disease. This presentation was given at the American Association of Neurological Surgeons Annual Meeting, Nashville, Tennessee. April 30, 1990. (Panelist) 6. Factors Affecting Transplant Survival. This presentation was given at Neurobiology for Neurosurgeons, Woods Hole, Massachusetts. November 5, 1991. 7. Primate Models of Parkinson’s. This presentation was given at the Neurosurgical Horizons in Parkinson’s Disease, United Parkinson Foundation, Chicago, Illinois. December 15, 1991. 8. Etiology and Treatment of Parkinson’s and Alzheimer’s Diseases. This presentation was given at Health Technology Associates, Chicago, Illinois. December 17, 1991. 9. Functional Restoration in the CNS: Where do we stand? This presentation was given at the American Association of Neurological Surgeons, Boston, Massachusetts. April 28, 1993. 10. Neural Transplantation. This presentation was given at the Congress of Neurological Surgeons 43rd Annual Meeting, Vancouver, British Columbia. October 5, 1993. (Panelist) 11. Neurotrophic Factors and Parkinsonism. This presentation was given at the Meacham Neurosurgical Society Annual Meeting, Nashville, Tennessee. October 22, 1993. 12. Antisense DNA as a Potential Treatment for Leukemic Meningitis. This presentation was given at the Meacham Neurosurgical Society Annual Meeting, Sea Land, Georgia. July 18, 1994. 13. Leukemic Meningitis-a Model in the Nude Rat and Neural Transplantation, from Lab to Clinic (and back). These presentations were given at the Meacham Neurological Society Annual Meeting, Sea Land, Georgia. July 17-19, 1995. 14. Growth and Gliomas and Delivery of Large Molecules to the Brain Parenchyma. These presentations were given at Vanderbilt Meacham Neurosurgical Society Annual Meeting, Vanderbilt University, Nashville, Tennessee. June 27-29, 1996. 15. Fetal Kidney Tissue Augments the Function and Cell Survival of Fetal Doapminergic Tissue when Cografted in an Animal Model of Parkinson’s Disease. This presentation was given at the American Association of Neurological Surgeons, Denver, Colorado. April 12-17, 1997. (Discussant: Scientific Session III).
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16. Cavernous Angiomas and Gender Effects in GBM. These presentations were given at the Meacham Neurosurgical Society Annual Meeting, Sea Island, Georgia. July 20-23, 1997. 17. Consultant’s Corner: Management of Astrocytomas. This presentation was given at the Congress of Neurological Surgeons Annual Meeting, New Orleans, Louisiana. September 29October 1, 1997. 18. Low Grade Gliomas. This presentation was given at Vanderbilt Meacham Neurological Society, Nashville, Tennessee. June 11, 1999. 19. Update: Estrogen and Glioblastoma. This presentation was given at Vanderbilt Meacham Neurological Society, Nashville, Tennessee. June 12, 1999. 20. Chiari and Tethered Cord. This presentation was given at Vanderbilt Meacham Society Annual Meeting, Nashville, Tennessee. November 2-4, 2001. 21. Intrathecal Baclofen – the Neurosurgeons Role. This presentation was given at the 2nd Annual Neurosurgical Forum, Ponte Vedra Beach, Florida. March 17, 2005. 22. Gamma Knife Thalamotomy . This presentation was given at the Neurosurgical Forum, Jacksonville, Florida. March 17, 2006. 23. Neurosurgical Pain Management-Cancer Pain: History Lesson or Resurgent Field. This presentation was given at the Neurosurgical Forum, Jacksonville, Florida. March 15-17, 2007. 24. Current Treatment of Brain Metastasis. This presentation was given at the Neurosurgical Forum, Jacksonville, Florida. March 6-8, 2008. 25. Intrathecal Baclofen for Stroke. This presentation was given at the Neurosurgical Forum, Jacksonville, Florida. March 8, 2011. 26. Stereotactic Surgery in Tuzla, Bosnia. This presentation was given at the 9th Annual Neurosurgical Forum, Ponte Vedra Beach, Florida. March 16, 2012.
Invited Presentations (International): 1. Neural Transplantation: An Update. This presentation was given at the Academic Neurosciences Meeting-Institute of Neurological Sciences, Glasgow, Scotland. August 4, 1989. 2. Spinal Cord Lesions Posing Challenges: Spinal Dural Arteriovenous Fistulas. This presentation was given at the 9th International Congress of Neurological Surgery, New Delhi, India. October 12, 1989. (Panelist)
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3. Mechanisms of Functional Recovery after Brain Implantation in Subhuman Primates. This presentation was given at the XIVth International Symposium of the Fulton Society-The Neurobiology of Brain Implants, New Delhi, India. October 27, 1989. 4. Deep Brain Stimulation for Treatment of Parkinson’s Disease. This presentation was given at the 1st Bosnia and Herzegovina Congress of Neurology, Tuzla, Bosnia and Herzegovina. May 912, 2002. Service to the Profession: 1. I have served as a Journal Reviewer for the following Journals: - Cancer Letters - Acta Medica Saliniana - Neuroscience Letters - BBA-Molecular Cell Research - I now sit on a panel of reviewers and am randomly called upon to review selected submissions for “Cancer Letters”. 2. I am on the International Editorial Council of the Bosnian Journal (as of February 2011), Bosnia Herzogovina Surgery. Service to the Public: 1. 1991 to 1995: “Think First” of Western New York Head Injury Prevention and Awareness Advisor and factual speaker, giving presentations in local schools. 2. 1997 to Present: Parkinson’s Wellness Group of Western New York, providing support and awareness to patients and their families. I was also the Surgical Advisor. I spoke at meetings in West Seneca, Amherst, Niagara Falls and Jamestown. I deliver a lecture at the yearly symposium. 3. 2006 to 2008 and 2010 to Present: Board Member of Parkinson’s Association of Western New York , Local Chapter of National Parkinson Foundation. Awareness and fundraising support groups like the Parkinson’s Wellness Group.
University Service: 1. Corporate Special Care Units Committee, Buffalo General Hospital, 1990-1997. 2. Surgery Search Committee for the Chief of Surgery, Buffalo General Hospital, 1991-1993. 3. Animal Care Committee, VA Medical Center, 1991-1994. 4. Medical Executive Committee, Buffalo General Hospital, 1991-1995. 5. Medical Administrative Committee, Buffalo General Hospital, 1991-1995. 26
6. Staff Executive Committee, Buffalo General Hospital, 1991-1995. 7. Clinical Chief of Neurosurgery, Buffalo General Hospital, 1991-1995. 8. Ad Hoc Committee-Criteria for the Determination of Brain Death, Buffalo General Hospital, 1994. 9. Blood Products Committee, Roswell Park Cancer Institute, 1998-2005. 10. OR Committee Member, Buffalo General Hospital, 2002-Present. 11. OR Committee Member, Roswell Park Cancer Institute, 2009-Present.
Medical School Service: 1. Faculty Council, 1990-1994. 2. Subcommittee of Faculty Council: Appointments, Promotions, Tenure and Privileges Committee, 1992-1993. 3. Committee to develop Neuroscience Graduate Course, 1994-1995. 4. Clinical Promotions Committee, 1999-2003. 5. Unqualified Ad Hoc Committee for Promotions, 2009-2012. Departmental Service: 1. Director of Research, 1990-1997. 2. Coordinator for Research Elective for Residents, 1990-2008. 3. Surgical Director, Comprehensive Movement Disorders Center, 1997-Present. 4. Resident Applicant Reviewer; I read every application and selected applicants to be invited for an interview, 1995-2009. 5. Residency Site Director, Buffalo General Hospital and Roswell Park Cancer Institute, 1997Present. Courses Taught: 1. Cortex/forebrain Lecture Series, State University of New York at Buffalo. Topic: Transplants, regeneration, 1992-1994, 1996. 27
2. Incoming Medical Resident Orientation Series: “Neurological/Neurosurgical Emergencies”, June 1993. 3. Department of Gynecology and Obstetrics, Morbidity-Mortality Conference, Buffalo General Hospital: Subarachnoid hemorrhage during pregnancy, July 23, 1994. 4. Incoming Medical Resident Orientation Series: “Neurological/Neurosurgical Emergencies”, June 27, 1995. 5. Visiting Professor to Tusla, Bosnia teaching “The Use of the Stereotactic Frame in Neurosurgery”. September 26 – October 1, 1998. 6. Pathophysiology Course, SUNY Buffalo and Roswell Park Cancer Institute, taught yearly. The topic is The Nervous System: Brain Tumors and Neurodegenerative Diseases. April 19982002. 7. Guest Speaker at Pathophysiology Course, SUNY @ Buffalo School of Medicine, Buffalo, NY. The topic was “The Nervous System”. 1998-2003. 8. Clinico-Pathological Correlation Conference Pathology Course, SUNY @ Buffalo School of Medicine, Buffalo, NY. The topic was “Head Injury”, taught with Dr. Peter Ostrow. 19982003. 9. Guest Speaker for General Pathology Course given at SUNY @ Buffalo School of Medicine, Buffalo, NY. The topic was “Head Trauma”, 2001-2003. 10. Intrathecal Baclofen Therapy 4 hour didactic and hands on course given to local MD’s, PA’s and NP’s, April 4, 2009. 11. Resident Education: I make daily teaching rounds with a Neurosurgical Resident at Buffalo General Hospital. A Resident scrubs with me for my surgical cases. In addition, I attend the following weekly or bi-weekly meetings, which are for Resident education: Neuropathology biweekly conference, Gamma Knife biweekly conference, weekly Neurosurgery morbidity and mortality conference, weekly Neurosurgery Grand Rounds, biweekly Roswell park Brain Tumor Board, and biweekly Neurosurgery/Neurology conference. Other Educational Activities: 1. Clinical Mentor for students, medical students, and Neurosurgical Residents in my lab, 1990present: - Anna DeVilliers, M.D., Neurosurgery Resident (January-June 1991) - Ahmad Zakeri, M.D., Neurosurgery Resident (1991-1992) - Hideo Asada, M.D., Post-Doctoral Fellow (1992-1995) - Nasser Razack, Medical Student, SUNY@ Buffalo (Summer 1993) - Mike Cioffi, Post-Graduate student, SUNY @ Buffalo (Fall 1994) 28
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Jeff Stiles, Ph.D. program, Pathology. I was on his thesis committee, and part of his thesis work was done in my lab. (1994-1996) Agnes Lis, MS Research Assistant. She went from my lab to a Ph.D. program at Nencki Institute, Warsaw, Poland. I was one of her thesis advisors; she pursued work in my lab, receiving her Ph.D. in 1999. She also did per post-doc in my lab. (1994-1997, 1999-2000) Kristal Williams, Undergraduate student from Texas A & M (Summer 1995) John Pollina, M.D., Neurosurgery Resident (1995-1996) Allison Duncan, Undergraduate student SUNY @ Buffalo, July 1996-1999 Bryan Scott, Medical Student SUNY @ Buffalo, 1997-2000 Agnes Lis, Post-doc in my lab, 1999-2000 Steve Selkirk, Ph.D. program, Pathology. I was on his thesis committee and part of his thesis work was done in my lab. We collaborated on another project while he was a Neurology Resident, 1999-2002. Lyle Ostrow, Ph. D. I was on his thesis committee and part of his thesis work was in my lab, 2001-2002 Jay Morrow, Ph.D. Pathology program; I was on his thesis committee. Part of his thesis work was done in my lab, 2001-2006. David Piccioni, Graduate student; I was on his thesis committee and part of his research was done in my lab. He continued to work in my lab after completing his Ph.D., 2002-2003. Justin Gorski, University of Rochester Undergraduate. He did a preceptorship in my lab, 2006.
Clinical Teaching: -
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Jennifer Jennings, Nurse Practitioner student took a one month elective in my clinic, 2000. Jennifer Williams, Medical Student. She did a preceptorship in my clinic and in the O.R., summer 2001. Justin Zbrezny, Undergraduate student. He did a month long preceptorship in my clinic and in the O.R., 2003. Justin Gorski, Pre-clinical Medical Student, University of Rochester. He spent 2 weeks with me, observing both my clinic and O.R., and attending conference, August 1-16, 2006. John Greenert, Oklahoma Undergraduate student, pursuing Medical school. He observed my clinic, O.R., and conferences, May 16-18, 2007. Cara Doyle, Starpoint High school student with desire to become a Nurse Practitioner. She observed/shadowed my clinic and O.R., August 2, 9, and 16, 2007. Lacey Bromley, University at Buffalo Doctorate of Physical Therapy student, did clinical observation on Baclofen pumps and O.R. observation on pump and catheter placement, October 23, 2007. Brad Andrews, University at Buffalo Doctorate of Physical Therapy student, did a clinical observation on Baclofen pumps and O.R. observation on pump and catheter placement, October 23, 2007. Michelle Brian, Physician Assistant student, did a preceptorship in my clinic and O.R., Fall 2007. Andrew Wensel, M.D., Strong Memorial Hospital Chief Resident of Neurosurgery, observed Deep Brain Stimulation surgery in my O.R. (2 electrode placements and pulse generator placement), June 2, 2009. I had 20 University at Buffalo Nursing students precept in my clinic and O.R., 2009 and 2010.
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Sabareesh Natarajan, Pre-Resident Fellow, rotated and observed one week during clinic, O.R., and conference, January 11-February 4, 2010. Sue Nichter, P.A., Buffalo Medical Group, observed Deep Brain Stimulation surgery in my O.R., February 3, 2010. Ian Lund, Daemen College Physician Assistant student, did a preceptorship in my clinic and O.R. He observed clinic, Rounds, O.R. and conferences, February 8-March 5, 2010. Julie Otto and Bonnie Handke, Medtronic Neurologic, observed my O.R. for insertion of pump and catheter and Deep Brain Stimulation, February 23-24, 2010. Michelle Burack, M.D., visiting from the University of Rochester, observed Deep Brain Stimulation with Micro Electrode Recording with teaching from myself, Dr. Trinidad and Dr. Stockton, March 10, 2010 and September 29, 2010. Ashley Savage, University at Buffalo Doctorate of Physical Therapy student observed my clinic on pump management, September 16, 2010. Bonnie Handke, Medtronic Neurologic, observed my O.R. during Deep Brain Stimulation Surgery, October 13, 2010. Bethany Bogdan, University at Buffalo Doctorate of Physical Therapy student, observed my clinic on pump management, October 21, 2010. Ashley Savage, Maria Rundell, and Bethany Bogdan, University at Buffalo Doctorate of Physical Therapy students observed the implantation of a pump and catheter in my O.R., October 22, 2010. Dr. Bela Ajtai and Jason Santiago, P.A. observed my clinic on pump management, February 24, 2011. Jason Santiago observed my O.R. during a surgical implantation of a pump and catheter, February 25, 2011. Dr. Joel Kent, M.D., Rochester, N.Y., observed my clinic in pump management and my O.R. in pump and catheter implantation, March 1, 2011. Lindsay Mandrino, Daemen College Physician Assistant student, did a preceptorship in my clinic and O.R., March 7-April 1, 2011. Debbie McConnell, Medtronic Neurologic, observed Deep Brain Stimulation as part of a “Best Clinical Practices Project”. This was a New Product Development Project, March 23, 2011. Becky Buttacio, Daemen College Physician Assistant student, did a preceptoship in my clinic and O.R., October 17 – November 11, 2011. Erin Filippini, UB Medical Student, observed Deep Brain Stimulation, February 22, 2012. Kristen Beck, PT, Meredith Ford, PT, Jay Mennel, PT, three PTs from Texas Children’s Hospital, Houston, TX, observed my Spasticity clinic, 2/24/12. Dan Keller and Shaughn Reagan, University at Buffalo Physical Therapy students, observed my clinic during an intrathecal baclofen trial, 4/16/12.
Clinical/Grant Research Activities: -
Veterans Administration Research Advisory Group “Injury-induced regeneration in parkinsonian rodents”
(Oct.’91-Sept. ’93) $41,000
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Sinsheimer Foundation “Injury-induced regeneration in parkinsonian animals”
(Sept.’92-Sept.’95) $75,000
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Veterans Administration Merit Review Grant
(Oct.’92-Oct.’95) $140,000
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“Injury-induced regeneration in parkinsonian models” -
Buffalo General Foundation “Origin of sprouting fibers in hemiparkinsonian monkeys”
(April ’92-April ’93) $10,520
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Buffalo General Foundation “Trophic factor infusion in hemiparkinsonian monkeys”
(July ’93-June ’94) $19,350
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Troup Fund “Mutagenesis of angiogenic mediators in glial tumors using the nude animal model”
(July ’94-June ’95) $15,230
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Roswell Park Alliance Foundation (April ’00-April ’01) “Implantation of Genetically Modified Astrocytes Into Rat Brains: Gene Expression and Functional Effects”. The major goal was to develop practical system to harvest adult astrocytes and transform them in the rat brain. We have successfully accomplished harvest, transformation and implantation are now studying gene expression and functional consequences in an ongoing project.
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Entremed Inc. (Sept ’00-Spet ’05) $17,568 “2-Methoxyestradiol Therapy for Brain Tumors”. The major goal was to evaluate 2Methoxyestradiol as a therapy for glial tumors in a nude rat intracerebral model.
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Troup Fund for Cancer Research (Feb ’02-Feb ’02) $20,923 “Estrogen Matabolites as Novel Therapy for Human Glial Tumors. The major goal was to evaluate 2-Methoxyestradiol and other estrogen metabolites in vitro and in vivo as novel bio-active agents to inhibit all growth and angiogenesis.
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Walter Zurowksi Sr. Memorial Fund “Use of Peripheral Blood Stem Cells in the Rat Brain”
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EntreMed Inc. (Nov ’05-Nov ’06) $25,596 “Effects of ENMD-1198 Administration on Human Glioblastoma Multiforme in a Subcutaneous Nude Rat Model”. The major goal was to evaluate ENMD-1198 (second generation formulation of 2ME2) as a therapy for glial tumors and to find the most effective treatment regimen.
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Med Immune LLC. (May ’09-July ’11) $25,641 “Monoclonal Antibody Therapy in an Animal Model of Glioblastoma Multiforme”. The major goal was to evaluate the efficacy of ang2 and PDGFRα monoclonal antibody therapies in a nude rat model of human glioblastoma multiforme.
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Incuron LLC. (Aug ’10-current) $6,170 “Effect of Curaxin (CBL0137) in an Orthotopic Rat Model of Glioblastoma Multiforme”. The major goal is to evaluate the efficacy of CBL0137 in a nude rat model of glioblastoma multiforme.
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DOD (DM102091)
(July ’01-June ‘03) $10,000
(Feb ’11-Feb ’14) $61,790 31
“The Use of Inhibitors of Mechanosensitive Ion Channels as Local Inhibitors of Peripheral Pain”. The major goal is to gain understanding of how mechanical stress activates mechaosensitive ion channels in nerve and how GsMTx4 and related peptides can suppress that response. I am a Sub-Investigator. The total grant is $1.3 million. International Service What is now Kaleida, entered into a partnership with the University Klinikal Center, Tuzla, Bosnia, to assist the latter to re-build its medical system. My involvement began in 1996 with the arrival of the first of two Bosnian Neurosurgical Residents. After the partnership was concluded in 1998, I continued to work with the Department of Neurosurgery and will continue that work as my health and energy permit. 1996 - 1998: Partnership agreement with support from the United States Agency for International Development. 1996 - June 1997: Dr. Mirsad Hadzic spent 6 months in the Department of Neurosurgery at the University at Buffalo. I coordinated his visit and clinical work. July – December 1997: Dr. Zlatko Ercegovic spent 6 months in the Department of Neurosurgery at the University at Buffalo. I coordinated his visit and clinical work. September 26 – October 1, 1998: I traveled to Tuzla with other Kaleida professionals. With the USAID, I solicited donations of surgical equipment for the Department of Neurosurgery, Tuzla. The most important piece of equipment was a stereotactic frame. While in Tuzla, I taught the Neurosurgeons, Scrub Techs and Radiologists how to use the frame. I did 2 operations using the frame, teaching Drs. Hodzic and Ercegovic. The closing ceremony of the Partnership was held during the trip to Tuzla. April 15 – May 10, 2001: I arranged for and financed a visit to Buffalo for Dr. Hodzic. He worked daily in the Department of Neurosurgery learning new operative techniques. May 9 - 12, 2002: I was invited to speak at the 1st Bosnia and Herzegovina Congress of Neurology. This was the 1st Medical Meeting held in Tuzla since the war. I also brought more donated surgical equipment and instructed surgeons and staff in its use. I provided consultation to Dr. Haun Brkic, Chairman of Neurosurgery, Tuzla. This resulted in a strategic Neurosurgical Development plan in Tuzla. We identified Carotid Endartesectomy as the next operative preocedure to be developed, due to their high-incidence of carotid atheroscleorsis. July 2004: I was an invited speaker at “Summer University”, Tuzla University Medical Center. I brought my partner, Dr. Jim Budny with me since he is an expert in carotid artery surgery. Dr. Budny worked with the surgeons, and I worked with the O.R. staff, Radiology, Neurology, and the Director of the Klinikal Center to prepare for the new cerebrovascular program. April 2005: Dr. Budny, Dr. Stockton and myself went to Tuzla. Several carotid endarterectomies were done by Drs. Budny, Hodzic and Ercegovic with EEG monitoring done by Dr. Stockton. I, again, worked with the Klinikal Director and Chairman of Neurosurgery on long-range planning, including the build-out of their new hospital. March – May 2007: Dr. Hodzic secured a traveling Fellowship from the American Association of Neurological Surgeons, and Dr. Ercegovic was supported by the Department of Neurosurgery, SUNY at 32
Buffalo. They spent 3 months on the clinical services of Pediatric Neurosurgery at Women and Children’s Hospital, Spinal Surgery (primarily) at Millard Fillmore Gates Hosopital, and Functional Neurosurgery at Buffalo General Hospital. In addition, they spent time at Roswell Park Cancer Institute to be introduced to Stereotactic Radiosurgery. Dr. Hodzic worked with Dr. Stockton to learn how to use a portable monitor, which was purchased with funds from a private foundation and myself. November 2007: Dr. Hodzic became Chairman of Neurosurgery in Tuzla. November 2009: I was invited to the opening ceremony of their new hospital. I gave multiple lectures and worked with Dr. Hodzic and the Clinical Director to plan 2 new areas of collaboration; Spasticity Management and Stereotactic Radiosurgery. These 2 projects are on-going. I am working with the 2 companies who make the necessary equipment. My partners and I will supply the clinical training.
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