Pediatric Infectious Diseases

10.03.08

Significance of ID 

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Nationally, third leading cause of death in the United States—170,000 each year Globally, second leading cause of death, over half of which are children under the age of 5 Prevention and treatment  

Vaccines New medications or emerging resistance

Significance of ID 

In the news:  

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Emerging and Reemerging  

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FDA Clears New CDC Test to Detect Human Influenza HHS Announces New Steps in Anthrax Preparedness Chikungunya Outbreak, South India Rise and Persistence of Global M1T1 Clone of Streptococcus pyogenes

CDC Top 10 

Flu, MRSA, Vaccines and Immunizations, STDs

Societies, National organizations 

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Infectious Diseases Society of America (IDSA); http://www.idsociety.org Pediatric Infectious Diseases Society (PIDS): http://www.pids.org/

ID as a career-General thoughts 

Of 8,000 ID specialists a high degree of job satisfaction 

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intellectual challenge and the diversity of their career as the reason for this satisfaction. Recent graduates the most satisfied

High job satisfaction, growing demand, diverse career paths, and the opportunity to work on the hottest issues in medicine today make a career in infectious diseases an exciting and rewarding choice.

Career Opportunities 

Academic medicine  

Combination of clinical and scholarship Can differentiate as clinical expert 

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Transplant ID

Scholarship activities  

Research Infection Control  

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Pharmacy Committee 

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Including IT support for protocols Outbreak planning

Including IT support for protocols

Laboratory Director Involvement with National Society Administrative  

Division Chief Dean

Career Opportunities 

Practice Based Expert 

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Combination of general pediatrics and ID

Public Health 

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TB/HIV/vaccine clinics State Health  

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Outbreak Investigations Epidemiology

Government  

NIH-research focus CDC-epidemiology focus  EIS officer

Career Opportunities 

Pharmaceutical Industry  

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Clinical Research Director Consultant

International Health 

HIV

Faculty 

Manuel Amieva, M.D., Ph.D  

Assistant Professor Research Interests 

Intestinal bacterial pathogenesis 

Strategies that pathogens utilize to colonize and subvert the epithelial barrier  Helicobacter pylori  Listeria monocytogenes

Faculty 

Ann Arvin, M.D.  

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Vice Provost and Dean of Research Professor Research Interests 

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Molecular virology of varicella zoster virus (VZV) infection Functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections

Faculty 

Sharon Chen, M.D.  

Instructor Research Interests 

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Cytomegalovirus (CMV) infections and host immune response in different populations: neonates, children, transplant recipients Relationship between CMV infections and allograft rejection

Faculty 

Corry Dekker, M.D.  

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Professor Medical Director of Stanford LPCH-Vaccine Program Research interests 

Human response to natural virus infection and to vaccines  

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Congenital HCMV infection, Influenza vaccines (seasonal and avian), Malaria vaccine, vaccine adjuvants Children vs. adult responses to flu vaccine

Vaccine safety

Faculty 

Hayley Gans, M.D.  

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Assistant Professor Director, Pediatric Infectious Diseases Fellowship Research Interests 

Ontogeny of the Immune Response to viral vaccines 

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Viral infections in immunocompromised hosts 

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Measles, mumps, varicella, IPV Measles in HIV

Aerosol Measles Immunization

Faculty 

Kathleen Gutierrez, M.D.  

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Assistant Professor Coordinator, Integrated Infectious Disease Program Research Interests 

Antiviral therapies of neonatal viral infections 

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Congenital CMV infection

Epidemiology of pediatric infectious diseases   

Neonatal HSV MRSA Influenza

Faculty 

David Hong, M.D.  

Instructor Research interests 

Novel adjuvants for influenza vaccine

Faculty 

David Lewis, M.D.  

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Professor Director, Clinical Immunology Research interests 

Mechanisms limiting adaptive immunity, particularly that mediated by T cells, during early postnatal life.

Faculty 

Bonnie Maldonado, M.D.    

Professor Chief, Division of Pediatric Infectious Diseases Director, Infection Control Research interests 

Epidemiologic aspects of viral vaccine development 

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Prevention of perinatal HIV transmission  

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OPV

Interventional studies Long term natural history

Measles immunization 

Aerosol route of measles immunization

Faculty 

Philip Pizzo, M.D.  

Dean, Stanford School of Medicine Professor  

HIV Infections in immuncompromised hosts

Faculty 

Charles Prober, M.D.  

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Professor Senior Associate Dean of Medical Education Editor, Principles & Practice of Pediatric Infectious Diseases 2008 Research interests 

Epidemiology, pathophysiology, prevention, and treatment of infections in children.  

HSV, human herpes viruses Respiratory viruses

Training 

3 year fellowship minimum  

52 weeks clinical service A Scholarship project meeting these criteria -Peer reviewed publication which fellow has played a substantial role -In-depth manuscript describing a completed project -Thesis or dissertation written in connection with the pursuit of an advanced degree -An extramural grant application that has been accepted or favorably reviewed -A Progress report for projects of exceptional complexity

Training 

Additional Expectations  

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Grant writing Abstract submission and presentation at national meetings Manuscript preparation

Application Process 

Programs recruiting for 18-24 mo in future 

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Apply in second year to ensure continuous training Application dates are institution specific 

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Discussion of match

Letter of recommendation are most important 

Rotating at desired institution helpful