Paul E. Wise, M.D. D5248 Medical Center North – Vanderbilt University Medical Center – Nashville, TN 37232 – Phone: (615) 343-4612 – Fax: (615) 343-4615 Website: www.vanderbiltcolorectal.com Current Position Assistant Professor of Surgery Division of General Surgery, Department of Surgery, Section of Surgical Sciences Vanderbilt University Medical Center Director, Vanderbilt Hereditary Colorectal Cancer Registry (VUMC IRB# 061182) License/Certification Tennessee Medical License, May, 1999 Certified, American Board of Surgery, September, 2004 Certified, American Board of Colon and Rectal Surgery, September, 2005 Postdoctoral Training 7/2003-6/2004 Washington University School of Medicine, Barnes/Jewish Hospital, St. Louis, MO Fellow in Colon and Rectal Surgery 7/2001-6/2003 Vanderbilt University School of Medicine, Nashville, TN 7/1996-6/1999 Categorical Resident in General Surgery 7/1999-6/2001 Vanderbilt University School of Medicine, Nashville, TN Department of Surgery, Division of Hepatobiliary Surgery and Liver Transplantation Resident in Research Education 8/1992-5/1996 Johns Hopkins University School of Medicine, Baltimore, MD M.D. awarded May, 1996 8/1988-5/1992 Georgetown University, Washington, DC B.S. in Chemistry awarded May, 1992, magna cum laude Honors and Awards 1991 American Chemistry Society’s Award for Achievement in Chemistry 1992 Georgetown College of Arts and Sciences’ Chemistry Achievement Award 1998 Fellow (2007), American College of Surgeons (ACS) 1999 H. William Scott, Jr. Surgical Research Award 1999 Member, Society of American Gastrointestinal Endoscopic Surgeons (SAGES) 2000 Associate Member, Sigma Xi Scientific Research Society 2000 Member, Southeastern Surgical Congress (SES) 2000 Fellow (2008), American Society of Colon and Rectal Surgeons (ASCRS) 2000 Member, Society of Surgeons of the Alimentary Tract (SSAT) 2000 American Society of Transplantation Travel Award for Transplant 2000, Chicago, IL 2000 Member, Vanderbilt University School of Medicine Housestaff Advisory Council

2000 Coach, championship Vanderbilt faculty/staff intramural softball team, “The Rejections” 2000 Co-coach, championship Vanderbilt faculty/staff intramural flag football team, “LOB” 2001 Chair, 19th Annual Vanderbilt University Medical Center Research Forum 2002 Gold Medal Award winner, Southeastern Surgical Congress, for “Biliary Reconstruction is Enhanced with a Collagen-Polyethylene Glycol Sealant” 2002 Vanderbilt University Medical Student Housestaff Teaching Award 2002 Administrative Chief Resident, Vanderbilt University Medical Center, Department of Surgery 2003 Vanderbilt University J. William Hillman Award for the “resident deemed as the best teacher and role model by third and fourth year medical students” 2003 Harwell Wilson Award for Excellence as Surgical Resident 2003 Member, H. William Scott, Jr. Surgical Society 2005 Board Member, Medical Advisory Committee, Crohn’s and Colitis Foundation of America, Tennessee Chapter 2007 Member, American Medical Association 2007 Member, Continuing Education Committee for the American Society of Colon and Rectal Surgeons (3 year tenure) 2008 Coordinator, Capstone Course for Vanderbilt Medical School, Colorectal Cancer Sessions 2008 Abstractor for the journal Diseases of the Colon and Rectum 2008 Chairman, Medical Advisory Committee, Crohn’s and Colitis Foundation of America, Tennessee Chapter (2 year tenure) 2008 Elected as executive council member, Collaborative Group of the Americas on Inherited Colorectal Cancer (3 year tenure) 2008 Member, Medical Economic Outcomes Committee, Vanderbilt University Medical Center 2008 Member, Tissue Utilization Committee, Vanderbilt University Medical Center 2009 Member, Piedmont Society of Colon and Rectal Surgery 2009 Member, Program Committee for the American Society of Colon and Rectal Surgeons 2010 Annual Scientific Meeting, Minneapolis, MN. 2009 President-elect, Collaborative Group of the Americas on Inherited Colorectal Cancer (1 year tenure starting 2010).

Research Grants 1995 American Federation for Aging Research/John A. Hartford Foundation Medical Student Scholars Program Fellowship for Geriatric Research 1999

National Kidney Foundation/American Society of Transplant Surgeons Folkert Belzer, M.D. Research Award (2 years) – declined in order to accept NRSA

1999

National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases Individual National Research Service Award (NRSA) #1 F32 DK09959-01 (2 years) for “Cold Ischemia and Intracellular Calcium Release Channels”

2000

Industry-supported grant (1 year) from Cohesion Technologies, Inc., Palo Alto, CA with William C. Chapman, M.D. for “CoSeal Surgical Sealant for Biliary Reconstruction”

2006

Consultant/Site PI at Vanderbilt University Medical Center for American Society of Colon and Rectal Surgeons Career Development Award to Matthew Mutch, MD (of Washington University in St. Louis, MO) for “Molecular Signature Predicts Recurrence of Stage II Colon Cancer” (VUMC IRB# 060820).

2007

Site Principal Investigator for “A Phase 3, Double-Blind Randomized, Parallel-Group, Placebo-Controlled Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post Operative Ileus (POI)”, Progenics Pharmaceuticals, Inc., Delaware (VUMC IRB# 061263).

2007

Consultant, Veterans Administration Merit Award (Principal Investigator: Matthew Weinger, MS, MD), “Operating room workload and quality of care”, project #: IAF-06-085-2 (VUMC IRB# 060950).

2007

Site Principal Investigator for “A Prospective, Observational, Multicenter Study Assessing Early Postoperative Recovery Following Laparoscopic Partial Large Bowel Resection”, Adolor Corp., Pennsylvania. (VUMC IRB# 070230)

2008

Site Principal Investigator for “Phase III Placebo-Controlled Trial of Celecoxib in Genotype Positive Subjects with Familial Adenomatous Polyposis”, Pfizer Inc. (VUMC IRB# 080520)

Publications Janicki PK, Wise PE, Pinson CW. Interspecies differences in the activity of transporting plasma membrane Ca2+-ATPase (PMCA) in the liver [Abstract]. Hepatology 30(4, pt. 2): 113, 1999. Janicki PK, Wise PE, Pinson CW. Inhibitory effect of inhalation anesthetics on transporting plasma membrane Ca2+-ATPase (PMCA) in the pig liver [Abstract]. Hepatology 30(4, pt. 2): 270, 1999. Wise PE, Janicki PK, Belous AE, Washington MK, Pinson CW. Separation and characterization of the non-parenchymal cell fraction from the porcine liver [Abstract]. Gastroenterology 118: A81, 2000. Pinson CW, Feurer ID, Payne JL, Wise PE, Shockley S, Speroff T. Health-related quality of life after different types of solid organ transplantation. Ann Surg; 232(4): 597-607, 2000 (PMID 10998658). Wise PE, Janicki PK, Belous AE, Pinson CW. Cold preservation depresses endoplasmic reticulum Ca2+-ATPase (SERCA) activity in the pig liver [Abstract]. Hepatology 32 (4, pt. 2): 350, 2000. Wise PE, Janicki PK, Belous AE, Pinson CW. Differential Activity of the Ca2+-ATPases in porcine hepatocytes and sinusoidal endothelial cells. Surgical Forum; Volume LI: 330-2, 2000. Janicki PK, Wise PE, Belous AE, Pinson CW. Interspecies differences in hepatic Ca2+-ATPase activity and the effect of cold preservation on porcine liver Ca2+-ATPase function. Liver Transpl; 7(2): 132139, 2001 (PMID 11172397). Wise PE, Wiley DH, Feurer ID, Chapman WC, Wright JK, Pinson CW. Effect of dopamine infusion on hemodynamics after hepatic denervation. J Surg Res; 96(1): 23-29, 2001 (PMID 11180992). Wise PE, Pinson CW. Biliary complications of liver transplantation. Chapter in: Clavien P-A, Baillie JMB, Suhocki P, Eds. Diseases of the Gallbladder and Bile Ducts: Diagnosis and Treatment, Blackwell Science, Malden, MA; 2001.

Wise PE, Carr C, Donovan JE, Nagy R, Roman CD, Wudel JL. ABSITE Review 2001. Self published, January, 2001. Wise PE, Shi Y-Y, Washington MK, Chapman WC, Wright JK, Sharp KW, Pinson CW. Radical resection improves survival for patients with pT2 gallbladder carcinoma. Am Surg; 67(11): 1041-7, 2001 (PMID 11730220). Wise PE, Wright JK, Chapman WC, Drinkwater DC, Slovis BS, Pierson RN, Pinson CW. Heart-lungliver transplant for cystic fibrosis. Transplant Proc; 33(7-8): 3568-71, 2001 (PMID 11750518). Belous AE, Wise PE, Janicki PK, Pinson CW. Differential activity of plasma and endoplasmic reticulum membrane Ca2+-ATPases in porcine hepatocytes. Transplant Proc; 33(7-8): 3720-1, 2001 (PMID 11750585). Feurer ID, Wright JK, Payne JL, Kain AC, Wise PE, Hale P, Chapman WC, Speroff T, Pinson CW. Effects of hepatitis C virus infection and its recurrence after liver transplantation on functional performance and health-related quality of life. J Gastrointest Surg; 6(1): 108-15, 2002 (PMID 11986026). Chapman CW, Wright JK, Wise PE, Pinson CW. Techniques of exposure, hilar dissection, and parenchymal division in hepatic surgery. Chapter in: Pinson CW, Ed. Operative Techniques in General Surgery, 4(1): 13-32, W.B. Saunders Company, Philadelphia, PA; March, 2002. Wise PE, Wudel LJ, Belous AE, Allos TM, Kuhn SJ, Feurer ID, Washington MK, Pinson CW, Chapman WC. Biliary reconstruction is enhanced with a collagen-polyethylene glycol sealant. Am Surg; 68(6): 553-62, 2002 (PMID 12079138). Wise PE, Liou SS, Sulur P, Wright JK, Chapman WC, Meranze SG, Mazer MJ and Pinson CW. Hepatic artery chemoembolization for isolated colorectal metastases to the liver [Abstract]. J Gastrointest Surg; 7(2): 267, 2003. Wise PE, Holzman MD. Surgical anatomy of the gallbladder, liver, and biliary tree. Chapter in: MacFadyen B, Arregui M, Eubanks S, Peters JH, Soper NJ, Swanstrom LL, Eds. Laparoscopic Surgery of the Abdomen, Springer-Verlag, New York, NY; 2003. Kizilisik AT, Feurer ID, VanBuren DH, Wise P, Van Buren D, Hopkins J, Ray J, Nylander W, Shaffer D, Helderman JH, Langone AJ, Speroff T, Pinson CW. Effects of diabetes and cadaveric organs on functional performance and health-related quality of life after kidney transplantation. Am J Surg; 186(5): 535-9, 2003 (PMID 14599621). Fletcher ND, Wise PE, Sharp KW. Common bile duct papillary adenoma causing obstructive jaundice. Am Surg; 70(5): 448-52, 2004 (PMID 15156955). Knox CD, Feurer ID, Wise PE, Lamps LW, Wright JK, Chari RS, Gorden LD, Pinson CW. Survival and functional quality of life after resection for hepatic carcinoid metastasis. J Gastrointest Surg; 8(6): 653-9, 2004 (PMID 15358324). Wise PE, Mutch MG. Hereditary nonpolyposis colorectal cancer. Semin Colon and Rectal Surgery; 15(3): 136-46, 2004.

Thomas KT, Welch D, Trueblood A, Sulur P, Wise P, Gorden DL, Chari RS, Wright JK Jr, Washington K, Pinson CW. Effective treatment of biliary cystadenoma. Ann Surg; 241(5): 769-73, 2005 (PMID 15849512). Schwartz DA, Connolley CD, Koyama T, Wise PE, Herline AJ. Calcaneal Ultrasound Bone Densitometry Is Not a Useful Tool to Screen Patients with Inflammatory Bowel Disease at High Risk for Metabolic Bone Disease. Inflamm Bowel Dis; 11(8): 749-754, 2005 (PMID 16043991). Schwartz DA, White CM, Wise PE, Herline AJ. Use of endoscopic ultrasound to guide combination medical and surgical therapy for patients with Crohn's perianal fistulas. Inflamm Bowel Dis; 11(8): 727-32, 2005 (PMID 16043987). Wise PE, Schwartz DA. Management of Perianal Crohn’s Disease. Clin Gastroenterol Hepatol; 4(4): 426-30, 2006 (PMID 16616345). Wise PE, Kodner IJ. Surgical treatment of fecal incontinence. Chapter in Bieber, Sanfillipo, Horowitz, Eds. Clinical Gynecology, Elsevier, Philadelphia, PA; 2006. Griggs LR, Wise P, Herline A, Muldoon R, Schwartz DA. Adalimumab for Patient's with Crohn's Perianal Fistulas. American Journal of Gastroenterology 2006; 101: S459. Coburn LA, Wise PE, Schwartz DA. The successful use of adalimumab to treat active Crohn's disease of an ileoanal pouch during pregnancy. Dig Dis Sci; 51(11):2045-7, 2006 (PMID 17009112). Rosen MJ, Moulton DE, Little CA, Morgan WM, Yang E, Herline A, Muldoon RL, Wise PE, Polk DB, Schwartz DA. The Use of Endoscopic Ultrasound in Pediatric Patients with Perianal Crohn’s Disease. Gastroenterology 2007; 132: A443. West NE, Wise PE, Herline AJ, Muldoon RL, Schwartz DA. Carcinoid Tumors are Fifteen Times More Common in Patients with Crohn’s Disease. Inflamm Bowel Dis 2007; 13(9):1129-34 (PMID 17538985). M'Koma AE, Wise PE, Muldoon RL, Schwartz DA, Washington MK, Herline AJ. Evolution of the Restorative Proctocolectomy and its effects on the Gastrointestinal Hormones. Int J Colorectal Dis 2007; 22(10):1143-63 (PMID 17576578). Dossett LA, White LM, Welch DC, Herline AJ, Muldoon RL, Schwartz DA, Wise PE. Small Bowel Adenocarcinoma Complicating Crohn’s Disease: Case Series and Review of the Literature. Am Surg 2007;73(11):1181-7 (PMID 18092659). Pierre K, Wise PE. Chapter 125, Loop Ileostomy and Colostomy. Chapter in Resnick, Howards, McGuire, Preminger, and Smith, Jr., Eds. Hinman's Atlas of Urologic Surgery, 3rd edition. Elsevier, Philadelphia, PA. (submitted 2008). Spradlin NM, Wise PE, Herline AJ, Muldoon RL, Rosen M, Schwartz DA. A Randomized Prospective Trial of Endoscopic Ultrasound (EUS) to Guide Combination Medical and Surgical Treatment for Crohn’s Perianal Fistulas. Am J Gastroenterol 2008;103(10):2527-35 (PMID 18684178).

M’Koma AE, Wise PE, Muldoon RL, Schwartz DA, Herline AJ. Prevalence and outcome of anemia after restorative proctocolectomy: A clinical literature review. Dis Colon Rectum 2009;52(4):726-39 (PMID 19404082). Rosen MJ, Moulton DE, Koyama T, Morgan WM 3rd, Morrow SE, Herline AJ, Muldoon RL, Wise PE, Polk DB, Schwartz DA. Endoscopic ultrasound to guide the combined medical and surgical management of pediatric perianal Crohn's disease. Inflamm Bowel Dis 2009 [Epub ahead of print]. (PMID 19637325). Delaney C, Marcello P, Sonoda T, Wise P, Bauer J, Techner L. Gastrointestinal recovery after laparoscopic partial large bowel resection: Results of a prospective, observational, multicenter study. Surg Endosc 2009 (accepted pending revisions). O’Neil BH, Raftery L, Calvo BF, Chakravarthy AB, Ivanova A, Myers MO, Kim HJ, Chan E, Wise PE, Caskey LS, Bernard SA, Sanoff HK, Goldberg RM, Tepper JE. A phase I study of bortezomib in combination with standard 5-fluorouracil and external beam radiotherapy for the treatment of locally advanced or metastatic rectal cancer. Clinical Colorectal Cancer 2009 (submitted). Presentations Wise PE, Janicki PK, Pinson CW. Activity of the calcium ATPase pumps: effect of cold ischemia and inhalational anesthetics [Oral]. Transplantation Day, Vanderbilt University Medical Center, Nashville, TN, 1999. Wise PE, Janicki PK, Belous AE, Pinson CW. Inhibitory effect of inhalation anesthetics on transporting plasma membrane Ca2+-ATPase (PMCA) in the pig liver [Poster]. American Association for the Study of Liver Disease, Dallas, TX, October 28, 1999. Wise PE, Janicki PK, Belous AE, Pinson CW. Interspecies differences in the activity of transporting plasma membrane Ca2+-ATPase (PMCA) in the liver [Poster]. American Association for the Study of Liver Disease, Dallas, TX, October 28, 1999. Wise PE, Wiley DH, Feurer ID, Chapman WC, Wright JK, Pinson CW. The effect of dopamine infusion on hepatic and systemic hemodynamics following hepatic denervation [Oral]. Association of Veterans Affairs Surgeons, Seattle, WA, April 10, 2000. Wise PE, Janicki PK, Belous AE, Washington MK, Pinson CW. Separation and characterization of the non-parenchymal cell fraction from the porcine liver [Poster]. Digestive Disease Week, San Diego, CA, May 21, 2000. Wise PE, Janicki PK, Belous AE, Pinson CW. Differential activity of the Ca2+-ATPases in porcine hepatocytes and sinusoidal endothelial cells [Oral]. Fellows’ Conference 2000: Emerging Issues in Solid Organ Transplantation, Vail, CO, June 26, 2000 Wise PE, Janicki PK, Belous AE, Pinson CW. Differential activity of the Ca2+-ATPases in porcine hepatocytes and sinusoidal endothelial cells [Oral]. American College of Surgeons, Chicago, IL, October 26, 2000.

Wise PE, Janicki PK, Belous AE, Pinson CW. Cold preservation depresses endoplasmic reticulum Ca2+-ATPase (SERCA) activity in the pig liver [Poster]. American Association for the Study of Liver Disease, Dallas, TX, October 28, 2000. Wise PE, Shi Y-Y, Chapman WC, Wright JK, Sharp K, Pinson CW. Radical resection improves survival for patients with pT2 gallbladder carcinoma [Oral]. Southeastern Surgical Congress, New Orleans, LA, February 5, 2001. Wise PE, Janicki PK, Belous AE, Pinson CW. Interspecies differences in hepatic Ca2+-ATPase activity and the effect of cold preservation on these porcine pumps [Oral]. Society of University Surgeons, Chicago, IL, February 8, 2001. Wise PE, Shi Y-Y, Chapman WC, Wright JK, Sharp K, Pinson CW. Radical resection improves survival for patients with pT2 and pT3 gallbladder carcinoma [Oral]. Americas Hepato-PancreatoBiliary Congress, Miami Beach, FL, February 24, 2001. Feurer I, Payne J, Speroff T, Harrison C, Ball J, Lewis B, Coffey P, Lilley E, Wise P, Chapman WC, Wright JK, Pinson CW. Functional performance and health-related quality of life after liver transplantation are adversely affected by hepatitis C infection. Americas Hepato-Pancreato-Biliary Congress. Miami Beach, FL, February 24, 2001. Wise PE, Wright JK, Chapman WC, Drinkwater DC, Pierson RN, Pinson CW. Heart-Lung-Liver transplant for cystic fibrosis [Poster]. Americas Hepato-Pancreato-Biliary Congress, Miami Beach, FL, February 24, 2001. Wise PE, Shi Y-Y, Chapman WC, Wright JK, Sharp KW, Pinson CW. Radical resection improves survival for patients with pT2 and pT3 gallbladder carcinoma [Oral]. Vanderbilt University School of Medicine, Department of Surgery Grand Rounds, Nashville, TN, March 2, 2001. Van Buren DH, Feurer ID, Wise PE, Van Buren D, Hopkins J, Swanson S, Ray J, Nylander W, Richie RE, Goral S, Johnson K, Helderman H, Ynares C, Speroff T, Pinson CW. The effects of diabetes and cadaveric organs on functional performance and health-related quality of life after kidney transplantation. [Poster] Transplant 2001, Chicago, IL, May 14, 2001. Wise PE, Shi Y-Y, Chapman WC, Wright JK, Sharp KW, Pinson CW. Radical resection improves survival for patients with pT2 and pT3 gallbladder carcinoma [Poster]. Digestive Disease Week, Atlanta, GA, May 21, 2001. Feurer ID, Payne J, Wright JK, Speroff T, Kain A, Hale P, Harrison C, Coffey P, Wise P, Chapman WC, Pinson CW. Reemergence of hepatitis C virus infection after liver transplantation has an adverse effect on functional performance and health-related quality of life. International Liver Transplantation Society, Berlin, Germany, July, 2001. Wise PE, Wright JK, Chapman WC, Drinkwater DC, Pierson RN, Pinson CW. Heart-Lung-Liver transplant for cystic fibrosis [Oral]. 2001 A Transplant Odyssey, Istanbul, Turkey, August 20, 2001. Wise PE, Belous AE, Janicki PK, Pinson CW. Differential calcium pumping activity of the plasma and endoplasmic reticulum membranes in porcine hepatocytes [Poster]. 2001 A Transplant Odyssey, Istanbul, Turkey, August 20, 2001.

Pinson CW, Wise PE. Surgery in the patient with cirrhosis: what are the risks and how to approach them? [Postgraduate Course] American Association for the Study of Liver Disease, Dallas, TX, November 10, 2001. Wise PE, Shi Y-Y, Chapman WC, Wright JK, Sharp KW, Pinson CW. Radical resection improves survival for patients with pT2 and pT3 gallbladder carcinoma [Oral]. Nashville Surgical Society Meeting, Nashville, TN, January 8, 2002. Wise PE, Wudel LJ, Belous AE, Allos TM, Kuhn SJ, Feurer ID, Washington MK, Pinson CW, Chapman WC. Biliary reconstruction is enhanced with a collagen-polyethylene glycol sealant [Oral]. Southeastern Surgical Congress, Nashville, TN, February 3, 2002 (Gold Medal Award winner). Wise PE, Liou SS, Sulur P, Wright JK, Chapman WC, Meranze SG, Mazer MJ and Pinson CW. Hepatic Artery Chemoembolization for Isolated Colorectal Metastases to the Liver [Poster]. Americas Hepato-Pancreato-Biliary Congress, Miami Beach, FL, Februaury 28, 2003. Wise PE, Liou SS, Sulur P, Wright JK, Chapman WC, Meranze SG, Mazer MJ and Pinson CW. Hepatic Artery Chemoembolization for Isolated Colorectal Metastases to the Liver [Poster]. Vanderbilt University Research Forum, Nashville, TN, April 23, 2003. Fletcher ND, Wise PE, Sharp KW. Common Bile Duct Papillary Adenoma Causing Obstructive Jaundice [Poster]. Southeastern Surgical Congress, Atlanta, GA, February, 2004. Wise PE. A Colorectal Primer: What a Difference a Year Makes [Oral, invited lecture]. Vanderbilt University School of Medicine, Department of Surgery Grand Rounds, Nashville, TN, March 26, 2004. Wise PE. Surgical Treatment of Inflammatory Bowel Disease [Oral, invited lecture]. Crohn’s Colitis Foundation of America Local Chapter Meeting, Nashville, TN, September 11, 2004. Wise PE. Operative Therapy for Hereditary Colorectal Cancer [Oral, invited lecture]. Vanderbilt Ingram Cancer Center, Hereditary Cancer: Diagnosis, Management, and Genetics of Colorectal Cancer. Nashville, TN, January 15, 2005. Wise PE. Operative Therapy for Hereditary Colorectal Cancer [Oral, invited lecture]. Grand Rounds. Harton Regional Medical Center, Tullahoma, TN, January 20, 2005. Wise PE. Operative Therapy for Hereditary Colorectal Cancer [Oral, invited lecture]. United Ostomy Association. Nashville, TN, January 30, 2005. Wise PE. Advances in Colon and Rectal Surgery at Vanderbilt [Oral, invited lecture]. H. William Scott Society Meeting. Nashville, TN, April 8, 2005. Wise PE. Colon and Rectal Surgery: What Is It & How Did I “End” Up Doing It? [Oral, invited lecture]. Med Club, David Lipscomb University. Nashville, TN, April 25, 2005.

Ray A, Herdman C, Koyama T, Herline AJ, Wise PE, Muldoon RL, Schwartz DA. Crohn’s perianal fistulas and the incidence of incontinence [Poster]. Annual Meeting of the American College of Gastroenterologists, Honolulu, HI, October, 2005. Wise PE. Surgical Techniques in Familial Adenomatous Polyposis [Oral, invited lecture]. Collaborative Group of the Americas for Inherited Colorectal Cancer, 9th Annual Meeting. Salt Lake City, Utah, October 23, 2005. Wise PE. Surgical Therapy for Hereditary Colorectal Cancer [Oral, invited lecture]. Vanderbilt University School of Medicine, Department of Surgery Grand Rounds, Nashville, TN, January 7, 2006. Wise PE. Surgical Therapy for Hereditary Colorectal Cancer [Oral, invited lecture]. Wound-Ostomy Care Nursing educational seminar, Nashville, TN, February 16, 2006. Dossett L, White L, Herline AJ, Muldoon RL, Schwartz DA, Wise PE. Small bowel carcinoma complicating Crohn's disease [Poster]. Southeastern Surgical Congress, Lake Buena Vista, FL, February 20, 2006. Wise PE. Postgraduate Course: Laparoscopic right colectomy (IBD) [Oral, invited lecture]. Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Annual Meeting, Dallas, TX, April 27, 2006. Coburn LA, Maltz BE, Wise PE, Herline AJ, Muldoon RL, Koyama T, Schwartz DA. Post-operative complications related to surgical approach and medical therapy for inflammatory bowel disease [Poster], Digestive Disease Week, Los Angeles, CA, May 24, 2006. Wise PE. Credentialing and reimbursement for laparoscopic colectomy [Oral, invited lecture]. 86th Annual Surgical Update, Meeting of the International College of Surgeons, Nashville, TN, June 23, 2006. Forbes R, Riviello R, Richards WO, Muldoon RL, Herline AJ, Wise PE. Primary ileostomy adenocarcinoma: Case series and review of the literature [Oral]. Annual meeting of the Tennessee Chapter of the American College of Surgeons, July 28, 2006. Griggs LR, Wise PE, Herline AJ, Muldoon RL, Schwartz DA. Adalimumab for patients with Crohn’s perianal fistulas [Poster]. Annual Meeting of the American College of Gastroenterologists, October, 2006. Wise PE. Surgical treatment of inflammatory bowel disease [Oral, invited lecture]. Patient education seminar - Take Charge: Crohn's Disease and Ulcerative Colitis in the 21st Century; Crohn’s Colitis Foundation of America, Tennessee Chapter, Nashville, TN, August 19, 2006. Wise PE. Surgical treatment of inherited colorectal cancer [Oral, invited lecture]. Gastroenterology and Hepatology Update 2006, Nashville, TN, September 22, 2006. Wise PE. Discussant: Diverticular disease: Do the risks of emergent colectomy justify non-operative management strategies? [Oral, invited lecture]. Southeastern Surgical Congress, Savannah, GA, February 13, 2007.

Wise PE. Surgical issues with inflammatory bowel disease [Oral, invited lecture]. Patient education seminar; Crohn’s Colitis Foundation of America, Tennessee Chapter, Nashville, TN, August 18, 2007. Wise PE. Moderator: Scientific Sessions [Invited moderator], Collaborative Group of the Americas for Inherited Colorectal Cancer, 11th Annual Meeting, La Jolla, CA, October, 2007. Bohl J, Sturgeon D, Rao GG, Wise PE. Endometrioid Cancer: Case Report and Review of the Literature [Poster]. Collaborative Group of the Americas for Inherited Colorectal Cancer, 11th Annual Meeting, La Jolla, CA, October, 2007. Wise PE. Surgical Treatment of Hereditary Colorectal Cancer [Oral, invited lecture]. Middle Tennessee Oncology Nurses Meeting, Nashville, TN, February 7, 2008. Wise PE. New Modalities in Endoscopy Post-graduate Course: Colonoscopy [Oral, invited lecture]. Southeastern Surgical Congress, Birmingham, AL, February 9, 2008. Wise PE. Surgical Treatment of Hereditary Colorectal Cancer [Oral, invited lecture]. Sumner Regional Medical Center Tumor Board, Gallatin, TN, March 7, 2008. Wise PE. Course Instructor for Laparoscopic Colorectal Resections Cadaver Course [Invited Instructor], Washington University in St. Louis, MO, March 8, 2008. Forbes R, Herline AJ, Muldoon RL, Wise PE. Primary Ileostomy Adenocarcinoma: Rare Condition after Proctocolectomy [Poster]. Annual meeting of the Society of Surgeons of the Alimentary Tract (SSAT), Digestive Disease Week (DDW), San Diego, CA, May, 2008. Bohl J, Isbell J, Wise P, Muldoon R, Herline A. Defining the Surgical Trainee’s Learning for Laparoscopic Colorectal Resection [Oral]. Annual Meeting of the American Society of Colon and Rectal Surgeons, Boston, MA, June, 2008. Wise PE. Colorectal cancer: reviewing the standards of care to reach a cure [Oral, invited lecture and moderator]. Southern Medical Association Annual Scientific Assembly, Nashville, TN, August 8, 2008. Wise PE. Closest thing to a house call: Ask the surgeon [Oral, invited lecture]. Patient education seminar; Crohn’s Colitis Foundation of America, Tennessee Chapter, Nashville, TN, August 9, 2008. Wise PE. Group facilitator [invited], Foundations Teamwork Course, Vanderbilt School of Medicine, Nashville, TN, August 11, 2008. Wise PE. Colorectal cancer screening guidelines and hereditary colorectal cancer [Oral, invited lecture, webcast and teleconference], Tennessee Primary Care Association CME course, Nashville, TN, August 28, 2008. Wise PE. Moderator: Collaborative CGA Groups [Invited moderator], Collaborative Group of the Americas for Inherited Colorectal Cancer, 12th Annual Meeting, Cleveland, OH, September 6, 2008.

Wise PE. Inflammatory bowel disease: surgical update [Oral, invited lecture]. Gastroenterology and Hepatology Update 2008, Nashville, TN, September 19, 2008. Wise PE. Course Instructor for Laparoscopic Colorectal Resections Cadaver Course [Invited Instructor], Wright State University, Dayton, OH, September 20, 2008. Wise PE. New developments in Colorectal Surgery [Oral, invited lecture]. 5th Annual Update on the Management of Gastrointestinal Malignancies, Nashville, TN, October 3, 2008. Wise PE. Surgical treatment of hereditary colorectal cancer [Oral, invited lecture]. Gateway Medical Center Tumor Board, Clarksville, TN, November 5, 2008. Wise PE. Discussant: Video – Laparoscopic Assisted Low Anterior Resection for Rectal Adenocarcinoma [Oral, invited discussant]. Southeastern Surgical Congress, Atlanta, GA, February 9, 2009. Wise PE. Hereditary Colorectal Cancer [Oral, invited lecture]. Piedmont Society of Colon and Rectal Surgery, Spring Meeting, Key Largo, FL, March 7, 2009. Wise PE. High Colonics: the Straight Poop? [Oral, invited lecture]. Piedmont Society of Colon and Rectal Surgery, Spring Meeting, Key Largo, FL, March 8, 2009. Delaney C, Marcello P, Sonoda T, Wise P, Bauer J, Techner L. Gastrointestinal recovery after laparoscopic partial large bowel resection: results of a prospective, observational, multicenter study [Oral]. Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Annual Meeting, Phoenix, AZ, April 24, 2009. Wise P, Sturgeon D, McCutcheon T, Muldoon R, Herline A. Increasing high risk colorectal cancer patient identification through family cancer history investigation [Poster]. American Society of Colon and Rectal Surgeons Annual Scientific Meeting, Hollywood, FL, May 4, 2009. M’Koma AE, Wise P, Seeley EH, Washington MK, Schwartz DA, Herline AJ, Muldoon RL, Caprioli RM. Proteomic patterns of the colonic submucosa discriminates inflammatory colitides [Poster]. American Society of Colon and Rectal Surgeons Annual Scientific Meeting, Hollywood, FL, May 4, 2009. Wise PE. The Polyposis Syndromes: Definitions, Diagnoses and Basic Clinical Management [Oral, invited lecture]. American Society of Colon and Rectal Surgeons Annual Scientific Meeting, Hollywood, FL, May 5, 2009. Wise PE. Hereditary Colorectal Cancer: Identification and Treatment [Oral, invited lecture]. Northside Hospital 2nd Annual Oncology Nursing Symposium, Atlanta, GA, May 16, 2009. M'Koma AE, Seeley EH, Wise PE, Washington MK, Schwartz DA, Herline AJ, Muldoon RL, Caprioli RM. Proteomic Analysis of Colonic Submucosa Differentiates Crohn's and Ulcerative Colitis [Poster]. Digestive Diseases Week, Chicago, IL, June 1, 2009. Wise PE. Hand-assisted left colectomy [Oral, invited lecture]. American College of Surgeons, 9th Annual Clinical Congress, Chicago, IL, October 12, 2009.

Wise PE. Laparoscopic Colon and Rectal Surgery Cadaver Lab [Invited instructor]. American College of Surgeons, 9th Annual Clinical Congress, Chicago, IL, October 13, 2009. Wise PE. Moderator: Surgical Crossfire: Decision-making for the treatment of hereditary colorectal cancer and associated conditions. [Invited moderator]. Collaborative Group of the Americas for Inherited Colorectal Cancer, 13th Annual Meeting, Honolulu, HI, October 17, 2009

Pending Presentations Wise PE. Surgical Therapy for Crohn’s Disease [Oral, invited lecture]. Vanderbilt University Surgical Grand Rounds, Nashville, TN, January 29, 2010. Wise PE. Nuts and Bolts 2010 Video Presentations: Vascular pedicle identification and control in the obese patient. American Society of Colon and Rectal Surgeons Annual Scientific Meeting, Minneapolis, MN, May 16, 2010. Wise PE. Polyposis Syndromes: Who Needs Colectomy, When and Which Option? American Society of Colon and Rectal Surgeons Annual Scientific Meeting, Minneapolis, MN, May 18, 2010. Wise PE. Initial presentation with severe terminal ileal Crohn’s disease – Top down or bottom up? American Society of Colon and Rectal Surgeons Annual Scientific Meeting, Minneapolis, MN, May 19, 2010.