DEPARTMENT OF MEDICINE E-Mail Newsletter May - October 2011

Volume 4 Issue 3

Message from the Physician-in-Chief, Dr. Kevin Imrie Dear Colleagues: This fall has been very busy in the Department and at Sunnybrook in general. I wanted to take this opportunity to update you on some of the key things we are working on: 1.

Occupancy: After a relatively decent summer and early fall, the hospital has been consistently above 100% occupancy since early November. Each of the services has implemented strategies to defer admissions, shorten length of stay and facilitate discharge and our consulting services have really stepped up to provide expedited access to outpatient services to help expedite discharges. Thanks for your continued efforts.

2.

Hand Hygiene: This is a real good news story. We continue to see improvement in hand hygiene compliance with the rate exceeding 80% for the first time this year. Adherence amongst staff physicians is now comparable to other professions. There is definitely still work to be done as the board has set a target of 100% and compliance amongst our residents and fellows still lags behind. Thank you for making this a priority.

3.

Recruitment: The board has approved the Medical Human Resources Plan we put together. Over the next year, this plan will see significant targeted recruitment to strengthen our academic programs and address areas of clinical need. The process is already well underway for those starting in July 2012.

4.

Partnership issues: The Sunnybrook Department of Medicine Partnership will be nearing its first birthday soon. Thanks to Chris Morgan, Wissen Tam and the Management Committee, things are going very well. The transition has been successfully navigated and last month we reached an important milestone by formalizing the process to gain access to Scientific Research and Experimental Development Program (SRED) tax credits and flowing over $1,000,000 of SRED eligible funding to SRI to support our researchers. We continue to work on improving financial reporting to the partners, consolidating the employment of our research staff within SRI, and formalizing our HR processes.

5.

Freedom of Information and Protection of Privacy Act: Lastly, I wanted to briefly let you know about an important legislative change that could impact you. Recent amendments to Bill 122 which will come into effect January 1, 2012 will increase access of the public to hospital corporate records (not personal health information). We will be discussing this change at our upcoming executive meeting and will be providing information to each of the division heads to be shared with division members.

That is all for now. I hope to see you at our Holiday drop-in on December 13, 2011. Kevin

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Strategic Plan The Department’s Strategic Plan “Sharpening Our Focus - 2010-2015”, was developed in 2010. Goals were centred around four Priority Areas: 1. Quality Clinical Care - led by Dr. Steve Shadowitz, 2. Research - led by Dr. Rob Fowler, 3) Education – led by Dr. Eugenia Piliotis and 4. Sustainability and Accountability – led by Drs Kevin Imrie and Chris Morgan. We have had a successful start achieving most of our goals in the first year and we are now in the stags of defining goals for the remaining years of the Plan. The diagram below tracks our progress; goals in blue have been achieved. Strategic Priorities Short-term Goals (Years 1+2) Priority Areas • Implement innovative inpatient and • Deploy a General Internal Medicine rapid Quality Clinical Care

Research

ambulatory models of acute care to improve access and quality • Improve alignment with Sunnybrook’s strategic priority areas and programs • Implement innovative city-wide collaborations in areas such as obstetrical medicine, geriatrics and rheumatology

•

•

• •

• • •

within the DOM Pursue strategic recruitment of clinician scientists and investigators focused on: - Health services research - Quality and patient safety - Educational research and scholarship - Specific academic foci within clinical programs Strengthen the relationship of the DOM to SRI in support of our mutual priorities Improve the experience of our learners Advance educational leadership, research and scholarship Lead in the teaching of quality and patient safety

• Implement a sustainable new financial Sustainability and Accountability

•

• Improve support for clinical researchers

•

Education

referral clinic

• Ensure all divisions have processes for

management model

• Develop a sustainable recruitment plan that includes resource requirements • Improve faculty workplace satisfaction • Develop performance metrics for clinical care, research and education

•

expedited outpatient access for patients referred from the Emergency Department, rapid referral clinic and on inpatient wards Deploy obstetrical medicine clinics in partnership with the Women and Babies Program Implement a mechanism to support midcareer researchers Increase the Practice Plan research budget Increase support for scientists to be comparable with that offered by other sites in the Toronto Academic Health Science Network Implement a strategy to communicate accomplishments of our researchers throughout the hospital

• Improve the teaching space used for Morning Report

• Decrease the General Internal Medicine

patient census by 10% (major implications for GIM teaching) • Recruit a research assistant to support education scholarship Sustainability • Implement a new partnership model • Revise the terms of reference of financial committees • Establish process to take advantage of SRED credits • Implement a faculty well-being committee Accountability • Improve physician hand hygiene compliance from 60% to 100% • Reduce admission rate from the Emergency Department from 25% to 21% • Conduct external reviews of two divisions each year • Create a vibrant DOM web presence • Improve communication of DOM research and education accomplishments

Goals for Year for Year 3 Goals Onward Will 3 Build Onward onWill Build on Achievements Achievements in Years 1-2 in Years 1-2 and Address and Address Changing Changing Needs and Needs and Priorities Priorities

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Appointment

Dr. Gregory Choy Congratulations to Dr. Gregory Choy who was appointed Interim Division Head in the Division Of Rheumatology effective July 1, 2011. Dr. Choy joined the department in July 2004 and has proven to be an exceptional clinician and educator.

New Staff

Dr. Esther Bui and daughter The Department of Medicine, Division of Neurology and Obstetrical Medicine welcomes Dr. Esther Bui. Dr. Bui is a graduate of the University of Toronto who subsequently did neurology specialty training at the University of Toronto with further fellowship training in Epilepsy and Electroencephalography at the Krembil Neuroscience Centre. Dr. Bui is a Lecturer at the University of Toronto and will function as a clinician-teacher. Her area of academic interest is epilepsy in pregnancy, women's health in epilepsy and medical education. Clinically, Dr. Bui serves as an epilepsy consultant and hasa regular outpatient clinic for patients with epilepsy. Clinical appointments can be booked at extension 4992 (fax). She also has a special clinical interest in the peripartum care of women with epilepsy. Dr. Bui is located in Room A442 and can be reached at extension 5200.

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New Staff (cont’d)

Dr. Andrew Lim The Department of Medicine, Division of Neurology welcomes Dr. Andrew Lim. Dr. Lim is a graduate of the University of Toronto who subsequently did specialty training in Neurology at the University of Toronto with further fellowship training in Sleep and Circadian Biology at Harvard University where he also completed a Master of Medical Science in Clinical Investigation in the laboratory of Dr. Clifford Saper. He was also a staff neurologist in the Division of Sleep Medicine, Department of Neurology at the Beth Israel Deaconess Medical Center. Dr. Lim is an Assistant Professor at the University of Toronto and will function as a clinician-scientist. His area of academic interest is the genetic dissection of sleep and circadian traits using contemporary statistical genetic approaches, and the elucidation of their relationship to the risk, presentation, and treatment of common medical diseases, including stroke, heart disease, neurodegenerative disease, and cancer.? Clinically, Dr. Lim serves as a neurology and sleep medicine consultant and has a regular outpatient clinic. Clinical appointments can be booked at extension 2461. Dr. Lim is located in Room K3W-27 and can be reached at extension 85236.

Retirement

Dr. Isaac Dwosh Dr. Isaac Dwosh has retired from Active Staff status in the department. Dr. Dwosh served as Division Head of Rheumatology since April 2009. We would like to thank Isaac for his leadership of the division over the last few years and we wish him all the best in this next stage of his life.

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2011 DEPARTMENT OF MEDICINE AWARD WINNERS TEACHING Young Teacher Award

In-Patient Teaching Award

Dr. Michael Bernstein

Dr. Khalil Sivjee

Pre-clerkship Teaching Award

Ambulatory Teaching Award

Dr. Lynfa Stroud

Dr. Susanna Cheng

Continuing Education Teaching Award

Dr. Sheldon Tobe

Part time Teaching Award Part-time

Dr. Donald Livingstone

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2011 DEPARTMENT OF MEDICINE AWARD WINNERS (cont’d) Research Junior Investigator Award

Senior Investigator Award

Dr. Rick Swartz

Dr. Craig Earle

Mentorship

Leadership

William J. Sibbald Mentorship Award

Dr. Sandra Black

Department of Medicine Leadership Award

Dr. Rob. Fowler

Department of Medicine E-mail Newsletter Pg. 7

Honours & Awards Three of our Faculty are included among the UofT DOM Top 10 Teachers

Drs. Matthew Cheung and Scott Walsh

Dr. Steve Shumak

Cardiology Dr. Harindra Wijeysundera − Awarded the Canadian Cardiovascular Society Young Investigators Award for 2011. Endocrinology Dr. Ivy Fettes − Awarded the Canadian Society of Endocrinology and Metabolism - CSEM 2011 Robert Volpé Distinguished Service Award; awarded to a senior member of the CSEM who has made a significant contribution to the CSEM and the discipline of Endocrinology in two or more of the following areas: Research; Education and Clinical Service. General Internal Medicine Dr. Ayelet Kuper − Awarded the Canadian Society of Internal Medicine (CSIM) 2011 New Investigator Award. Medical Oncology & Haematology Dr. Matthew Cheung − Awarded the Jerry Scott Teaching Award in the Division of Hematology Dr. Sunil Verma: − Student was one of the winners in the Summer student poster day Clinical Epidemiology (CE): Raman Tatla, Supervisor: Dr. Sunil Verma Title of Project: A Review of Phase III Clinical Trials in Metastatic Breast Cancer: Clinical Endpoints and Quality of Life Dr. Urban Emmenegger − 2011 Young Investigator Award, Division of Medical Oncology, Faculty of Medicine, University of Toronto Neurology Dr. Mario Masellis: − Associate Editor, Journal: Current Pharmacogenomics and Personalized Medicine Respirology & Clinical Immunology Dr. Anu Tandon − Awarded the Respirology Resident Teaching Award

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Selected Publications 1. 2. 3. 4. 5. 6. 7. 8.

9. 10. 11.

12.

13. 14.

15. 16.

Antibiotic treatment duration for bloodstream infections in critically ill patients: a nat ional survey of Canadian infectious diseases and c ritical care specialists. Daneman N, Shore K, Pinto R, Fowler R. Int J Antimicrob Agents. 2011 Dec;38(6):480-5. Epub 2011 Oct 7. Oral high-dose glucocorticoids and Ofatumumab in fludarabine-resistant Chronic Lymphocytic Leukemia. Spaner DE. Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.329. [Epub ahead of print] No abstract available. PMID:22064354 [PubMed - as supplied by publisher] Serotonergic Function and Treatment of Behavioral and Psychological Symptoms of Frontotemporal Dementia. Herrmann N, Black SE, Chow T, Cappell J, Tang-Wai DF, Lanctôt KL. Am J Geriatr Psychiatry. 2011 Nov 4. [Epub ahead of print] PMID:21878805 [PubMed - as supplied by publisher] Roadway crash risks in recent immigrants. Redelmeier DA, Katz D, Lu H, Saposnik G. Accid Anal Prev. 2011 Nov;43(6):2128-33. Epub 2011 Jul 2. PMID: 21819843 [PubMed - in process] Missed opportunities for type 2 diabetes testing following gestational diabetes: a popul ation-based cohort study. Shah B, Lipscombe L, Feig D, Lowe J. BJOG. 2011 Nov;118(12):1484-90. doi: 10.1111/j.14710528.2011.03083.x. Epub 2011 Aug 22. PMID: 21864326 [PubMed - in process] Usability evaluation of order sets in a computerised provider order entry system. Chan J, Shojania KG, Easty AC, Etchells EE.BMJ Qual Saf. 2011 Nov;20(11):932-40. Epub 2011 Jul 31. PMID: 21807652 [ PubMed - in process] Real-time automated paging and decision support for critical laboratory abnormalities. Etchells E, Adhikari NK, Wu R, Cheung M, Quan S, Mraz R, Wong B, Pinto R, Mehta R, Morra D, Fowler R, Sibbald W, Abrams H, Rossos PG. BMJ Qual Saf. 2011 Nov;20(11):924-30. Epub 2011 Jul 1. PMID:21725046 [PubMed - in process] Chromosome 17 centromere (CEP17) duplication as a predictor of anthracycline response: evidence from the NCIC Clinical Trials Group (NCIC CTG) MA.5 Trial. Pritchard KI, Munro A, O'Malley FP, Tu D, Li X, Levine MN, Shepherd L, Chia S, Bartlett JM. Breast Cancer Res Treat. 2011 Nov 1. [Epub ahead of print] PMID: 22042366 [PubMed - as supplied by publisher] Patient and Physician Perceptions on Continuing Aromatase Inhibitors beyond the 5-Year Mark. Gandhi S, Towns K, Verma S. Breast J. 2011 Nov;17(6):620-9. doi: 10.1111/j.1524-4741.2011.01153.x. Epub 2011 Sep 21. PMID: 21943336 [PubMed - in process] Testing sleepiness and vigilance in the sleep laboratory. Coelho FM, Narayansingh M, Murray BJ. Curr Opin Pulm Med. 2011 Nov;17(6):406-11. PMID: 21881512 [PubMed - in process] Postpartum assessment of the Renin Angiotensin system in women with previous severe, early-onset preeclampsia. Hladunewich MA, Kingdom J, Odutayo A, Burns K, Lai V, O'Brien T, Gandhi S, Zimpelmann J, Kiss A, Miller J, Cherney D. J Clin Endocrinol Metab. 2011 N ov;96(11):3517-24. Epub 2011 A ug 31. PMID: 21880804 [PubMed - in process] Early management of newly diagnosed rheumatoid arthritis by canadian rheumatologists: a nat ional, multicenter, retrospective cohort. Tavares R, Pope JE, Tremblay JL, Thorne C, Bykerk VP, Lazovskis J, Blocka KL, Bell MJ, Lacaille D, Hitchon CA, Fitzgerald AA, Fidler WK, Bookman AA, Henderson JM, Mosher DP, Sholter DE, Khraishi M, Haraoui B, Chen H, Li X, Laupacis A, Boire G, Tomlinson G, Bombardier C. J Rheumatol. 2011 Nov;38(11):2342-5. Epub 2011 Sep 1. PMID: 21885485 [PubMed - in process] Identification of a r ole for the nuclear receptor EAR-2 in the maintenance of clonogenic status within the leukemia cell hierarchy. Ichim CV, Atkins HL, Iscove NN, Wells RA. Leukemia. 2011 Nov;25(11):1687-96. doi: 10.1038/leu.2011.137. Epub 2011 Jun 3. PMID: 21637284 [PubMed - in process] Evaluating Survivorship Care Plans: Results of a Randomized, Clinical Trial of Patients With Breast Cancer. Grunfeld E, Julian JA, Pond G, Maunsell E, Coyle D, Folkes A, Joy AA, Provencher L, Rayson D, Rheaume DE, Porter GA, Paszat LF, Pritchard KI, Robidoux A, Smith S, Sussman J, Dent S, Sisler J, Wiernikowski J, Levine MN. J Clin Oncol. 2011 O ct 31. [Epub ahead of print]PMID: 22042959 [ PubMed - as supplied by publisher] .Theory and Practice in the Design and Conduct of Graduate Medical Education. Hodges BD, Kuper A. Acad Med. 2011 Oct 28. [Epub ahead of print] PMID: 22042213 [PubMed - as supplied by publisher] Randomized trial of tamoxifen versus combined tamoxifen and oc treotide LAR Therapy in the adjuvant treatment of early-stage breast cancer in postmenopausal women: NCIC CTG MA.14. Pritchard KI, Shepherd LE, Chapman JA, Norris BD, Cantin J, Goss PE, Dent SF, Walde D, Vandenberg TA, Findlay B, O'Reilly SE, Wilson CF, Han L, Piura E, Whelan TJ, Pollak MN. J Clin Oncol. 2011 Oct 10;29(29):3869-76. Epub 2011 Sep 12. PMID: 21911723 [PubMed - in process]

Department of Medicine E-mail Newsletter Pg. 9

Selected Publications (cont’d) 17. Completion of adjuvant chemotherapy and us e of health services for older women with epithelial ovarian cancer. Fairfield KM, Murray K, Lucas FL, Wierman HR, Earle CC, Trimble EL, Small L, Warren JL. J Clin Oncol. 2011 Oct 10;29(29):3921-6. Epub 2011 Sep 12. PMID:21911719 [PubMed - in process] 18. Comparison of mortality between nosocomial and c ommunity-acquired febrile neutropenia patients treated initially with cefazolin plus tobramycin: retrospective chart review. Elligsen M, Walker SA, Walker SE, Lepiane F, Lathia N, De'angelis C, Simor A. Eur J Clin Microbiol Infect Dis. 2011 Oct 6. [Epub ahead of print] PMID: 21975605 [PubMed - as supplied by publisher] 19. Administrative Hospitalization Database Validation of Cardiac Procedure Codes. Lee DS, Stitt A, Wang X, Yu JS, Gurevich Y, Kingsbury KJ, Austin PC, Tu JV. Med Care. 2011 O ct 5. [Epub ahead of print] PMID: 21979370 [PubMed - as supplied by publisher] 20. Who you know or what you know? Effect of examiner familiarity with residents on O SCE scores. Stroud L, Herold J, Tomlinson G, Cavalcanti RB. Acad Med. 2011 Oct;86(10 Suppl):S8-11. PMID: 21955775 [PubMed in process] 21. Psychological impact of recall on women with BRCA mutations undergoing MRI surveillance. Spiegel TN, Esplen MJ, Hill KA, Wong J, Causer PA, Warner E. Breast. 2011 Oct;20(5):424-30. Epub 2011 May 25. PMID: 21612928 [PubMed - in process] 22. How well is Helicobacter pylori treated in usual practice? Yogeswaran K, Chen G, Cohen L, Cooper MA, Yong E, Hsieh E, Rowsell C, Saibil F, Tinmouth J. Can J Gastroenterol. 2011 O ct;25(10):543-6. PMID: 22059158 [PubMed - in process] 23. Low CD40L levels and r elative lymphopenia in narcoleptic patients. Coelho FM, Pradella-Hallinan M, Pedrazzoli M, Soares CA, Fernandes GB, Murray BJ, Tufik S, Bittencourt LR. Hum Immunol. 2011 Oct;72(10):817-20. Epub 2011 May 30. PMID: 21669245 [PubMed - in process] 24. Implications of ambulatory blood pressure monitoring substudies on t he interpretation of clinical trials in hypertension: should the threshold for drug therapy be lower in older patients? Myers MG. J Clin Hypertens (Greenwich). 2011 O ct;13(10):703-5. doi: 10.1111/j.1751-7176.2011.00505.x. Epub 2011 Jul 27. No abstract available. PMID: 21974754 [PubMed - in process] 25. The effects of donepezil on c omputer-simulated driving ability among healthy older adults: a pilot study. Rapoport MJ, Weaver B, Kiss A, Zucchero Sarracini C, Moller H, Herrmann N, Lanctôt K, Murray B, Bédard M. J Clin Psychopharmacol. 2011 Oct;31(5):587-92. PMID:21869695[PubMed - in process] 26. High-dose methotrexate based chemotherapy with deferred radiation for treatment of newly diagnosed primary central nervous system lymphoma. Gerard LM, Imrie KR, Mangel J, Buckstein R, Doherty M, Mackenzie R, Cheung MC. Leuk Lymphoma. 2011 Oct;52(10):1882-90. Epub 2011 Jun 12.PMID:21663504[PubMed - in process] 27. The iScore Predicts Poor Functional Outcomes Early After Hospitalization for an Acute Ischemic Stroke. Saposnik G, Raptis S, Kapral MK, Liu Y, Tu JV, Mamdani M, Austin PC; on behalf of the Investigators of the Registry of the Canadian Stroke Network and the Stroke Outcome Research Canada (SORCan— www.sorcan.ca) Working Group. Stroke. 2011 Sep 29. [Epub ahead of print] PMID:21960583[PubMed - as supplied by publisher] 28. Syncope triggered by a pr emature ventricular complex: A case of atrial fibrillation and par oxysmal atrioventricular block. Singh SM, Kadmon E, Suszko A, Chauhan VS. Heart Rhythm. 2011 Sep 23. [Epub ahead of print] No abstract available. PMID:21946338 [PubMed - as supplied by publisher] 29. Elevated bone turnover predicts for bone metastasis in postmenopausal breast cancer: results of NCIC CTG MA.14.Lipton A, Chapman JA, Demers L, Shepherd LE, Han L, Wilson CF, Pritchard KI, Leitzel KE, Ali SM, Pollak M.J Clin Oncol. 2011 Sep 20;29(27):3605-10. Epub 2011 Aug 22.PMID:21859992[PubMed - in process] 30. Clinical practice. Breast-cancer screening. Warner E.N Engl J Med. 2011 Sep 15;365(11):1025-32. Review. No abstract available. PMID:21916640 [PubMed - indexed for MEDLINE] 31. Achieving Quality Indicator Benchmarks and P otential Impact on C oronary Heart Disease Mortality.Wijeysundera HC, Mitsakakis N, Witteman W, Paulden M, van der Velde G, Tu JV, Lee D S, Goodman SG, Petrella R, O'Flaherty M, Capewell S, Krahn M.Can J Cardiol. 2011 S ep 13. [Epub ahead of print] PMID:21920697[PubMed - as supplied by publisher] 32. Lifetime risk of developing chronic obstructive pulmonary disease: a l ongitudinal population study. Gershon AS, Warner L, Cascagnette P, Victor JC, To T.Lancet. 2011 Sep 10;378(9795):991-6.PMID:21907862[PubMed - indexed for MEDLINE]

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Selected Publications (cont’d) 33. Introducing the Patient Safety Professional: Why, What, Who, How, and Where? Saint S, Krein SL, Manojlovich M, Kowalski CP, Zawol D, Shojania KG. J Patient Saf. 2011 S ep 8. [Epub ahead of print] PMID:21918486[PubMed - as supplied by publisher] 34. Temporal changes in emergency department triage of patients with acute myocardial infarction and the effect on outcomes.Atzema CL, Schull MJ, Austin PC, Tu JV.Am Heart J. 2011 Sep;162(3):4519.PMID:21884860[PubMed - indexed for MEDLINE] 35. Percutaneous coronary intervention with vs without on-site cardiac surgery backup: a systematic review and meta-analysis. Zia MI, Wijeysundera HC, Tu JV, Lee DS, Ko DT. Can J Cardiol. 2011 Sep;27(5):664.e9-16. Epub 2011 May 5. PMID:21546209[PubMed - in process] 36. New anticoagulants for atrial fibrillation: the beginning of a a new era in stroke prevention. Gladstone DJ, Earl KM, Bungard TJ, Cox JL, Bell A, Dorian P, Dean N, Huynh T, Chopra A, Eikelboom J, Shuaib A. Can J Neurol Sci. 2011 Sep;38(5):777-82. No abstract available. PMID:21856588 [PubMed - in process] 37. Occluded stent in an extraluminal plane of the right coronary artery. Zia MI, Madan M. J Cardiovasc Comput Tomogr. 2011 Sep-Oct;5(5):338-9. Epub 2011 Jun 29. PMID:21820379 [PubMed - in process] 38. Long-term safety and effectiveness of drug-eluting stents for the treatment of saphenous vein grafts disease: a population-based study. Ko DT, Guo H, Wijeysundera HC, Zia MI, Džavík V, Chu MW, Fremes SE, Cohen EA, Tu JV. JACC Cardiovasc Interv. 2011 Sep;4(9):965-73. doi: 10.1016/j.jcin.2011.06.009. PMID:21939936[PubMed - in process] 39. Short-term outcomes after symptomatic internal carotid artery occlusion. Burke MJ, Vergouwen MD, Fang J, Swartz RH, Kapral MK, Silver FL, Casaubon LK; Investigators of the Registry of the Canadian Stroke Network. Stroke. 2011 Sep;42(9):2419-24. Epub 2011 Jul 14.PMID:21757665[PubMed - indexed for MEDLINE] 40. Emerging trends in the treatment of triple-negative breast cancer in Canada: a survey. Verma S, Provencher L, Dent R. Curr Oncol. 2011 Aug;18(4):180-90.PMID:21874117[PubMed] 41. Benefit of repeat multiple sleep latency testing in confirming a possible narcolepsy diagnosis. Coelho FM, Georgsson H, Murray BJ. J Clin Neurophysiol. 2011 Aug;28(4):412-4. PMID:21811133 [PubMed - in process] 42. Determining whether a patient is feeling better: pitfalls from the science of human perception. Redelmeier DA, Dickinson VM.J Gen Intern Med. 2011 Aug;26(8):900-6. Epub 2011 Feb 19.PMID:21336670 [PubMed - in process] 43. The impact of endothelin-1 genetic analysis and job strain on ambulatory blood pressure.Tobe SW, Baker B, Hunter K, Kiss A, Perkins N, Gomez L, Feng Y, Wigg K, Barr CL.J Psychosom Res. 2011 Aug;71(2):97-101. Epub 2011 Mar 15.PMID:21767690 [PubMed - in process] 44. Unfractionated heparin for second trimester placental insufficiency: a pi lot randomized trial. Kingdom JC, Walker M, Proctor LK, Keating S, Shah PS, McLeod A, Keunen J, Windrim RC, Dodd JM. J Thromb Haemost. 2011 Aug;9(8):1483-92. doi: 10.1111/j.1538-7836.2011.04407.x.PMID:21689371[PubMed - in process] 45. Dynamic microbubble contrast-enhanced US to measure tumor response to targeted therapy: a proposed clinical protocol with results from renal cell carcinoma patients receiving antiangiogenic therapy. Williams R, Hudson JM, Lloyd BA, Sureshkumar AR, Lueck G, Milot L, Atri M, Bjarnason GA, Burns PN. Radiology. 2011 Aug;260(2):581-90. Epub 2011 May 9.PMID:21555352[PubMed - indexed for MEDLINE] 46. Proteinuria in special populations: pregnant women and children. Hladunewich MA, Schaefer F. Adv Chronic Kidney Dis. 2011 Jul;18(4):267-72.PMID:21782133 [PubMed - in process] 47. Reducing the risk of severe complications among patients with Clostridium difficile infection. Manek K, Williams V, Callery S, Daneman N. Can J Gastroenterol. 2011 Jul;25(7):368-72.PMID:21876858 [PubMed - indexed for MEDLINE] 48. Glioblastoma: patterns of recurrence and efficacy of salvage treatments. Oh J, Sahgal A, Sanghera P, Tsao MN, Davey P, Lam K, Symons S, Aviv R, Perry JR. Can J Neurol Sci. 2011 Jul;38(4):621-5. PMID:21672702 [PubMed - indexed for MEDLINE] 49. Proteins mediating collagen biosynthesis and accumulation in arterial repair: novel targets for anti-restenosis therapy. Osherov AB, Gotha L, Cheema AN, Qiang B, Strauss BH. Cardiovasc Res. 2011 Jul 1;91(1):16-26. Epub 2011 Jan 18. Review. PMID: 21245059 [PubMed - indexed for MEDLINE] 50. Paraspinal myopathy with novel shard-like compact aggregates of thin filaments. Keith JL, Zinman L, Cohen S, Young B, Bilbao J. Muscle Nerve. 2011 J ul;44(1):145-6. doi: 10.1002/mus.22093. Epub 2011 Jun 9. No abstract available. PMID:21660984 [PubMed - indexed for MEDLINE] 51. Pulmonary emboli after blunt trauma: Timing, clinical characteristics and natural history. Spencer Netto F, Tien H, Ng J, Ortega S, Scarpelini S, Rizoli SB, Geerts W. Injury. 2011 J un 29. [Epub ahead of print] PMID: 21722897 [PubMed - as supplied by publisher]

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Selected Publications (cont’d) 52. Choosing peritoneal dialysis reduces the risk of invasive access interventions. Oliver MJ, Verrelli M, Zacharias JM, Blake PG, Garg AX, Johnson JF, Pandeya S, Perl J, Kiss AJ, Quinn RR. Nephrol Dial Transplant. 2011 Jun 21. [Epub ahead of print] PMID: 21693682[PubMed - as supplied by publisher] 53. Ontario multidetector computed tomographic coronary angiography study: field evaluation of diagnostic accuracy. Chow BJ, Freeman MR, Bowen JM, Levin L, Hopkins RB, Provost Y, Tarride JE, Dennie C, Cohen EA, Marcuzzi D, Iwanochko R, Moody AR, Paul N, Parker JD, O'Reilly DJ, Xie F, Goeree R. Arch Intern Med. 2011 Jun 13;171(11):1021-9. Epub 2011 Mar 14. PMID: 21403014[PubMed - indexed for MEDLINE] 54. Influence of noninvasive cardiovascular imaging in primary prevention: systematic review and meta-analysis of randomized trials. Hackam DG, Shojania KG, Spence JD, Alter DA, Beanlands RS, Dresser GK, Goela A, Davies AH, Badano LP, Poldermans D, Boersma E, Njike VY. Arch Intern Med. 2011 Jun 13;171(11):977-82. Epub 2011 Mar 14. Review.PMID:21403010 [PubMed - indexed for MEDLINE] 55. A systematic approach to systemic contact dermatitis and s ymmetric drug-related intertriginous and f lexural exanthema (SDRIFE): a closer look at these conditions and an approach to intertriginous eruptions. Winnicki M, Shear NH. Am J Clin Dermatol. 2011 Jun 1;12(3):171-80. doi: 10.2165/11539080-000000000-00000. Review. PMID: 21469762[PubMed - indexed for MEDLINE] 56. Distribution of antiseptic resistance genes qacA, qacB, and smr in methicillin-resistant Staphylococcus aureus isolated in Toronto, Canada, from 2005 to 2009. Longtin J, Seah C, Siebert K, McGeer A, Simor A, Longtin Y, Low DE, Melano RG.Antimicrob Agents Chemother. 2011 Jun;55(6):2999-3001. Epub 2011 Mar 14.PMID:21402848[PubMed - indexed for MEDLINE] 57. Informed decision-making in elective major vascular surgery: analysis of 145 s urgeon-patient consultations. Etchells E, Ferrari M, Kiss A, Martyn N, Zinman D, Levinson W. Can J Surg. 2011 Jun;54(3):1738.PMID:21443835 [PubMed - indexed for MEDLINE] 58. In situ DNA repair assays as guides to personalized breast cancer chemotherapeutics: ready for prime time? Dent RA, Bristow RG. J Clin Oncol. 2011 Jun 1;29(16):2130-2. Epub 2011 A pr 25. No abstract available. PMID: 21519017 [PubMed - indexed for MEDLINE] 59. Visual attention deficits in Alzheimer's disease: relationship to HMPAO SPECT cortical hypoperfusion. Vasquez BP, Buck BH, Black SE, Leibovitch FS, Lobaugh NJ, Caldwell CB, Behrmann M. Neuropsychologia. 2011 Jun;49(7):1741-50. Epub 2011 Mar 4. PMID: 21377483 [PubMed - indexed for MEDLINE] 60. The direct medical costs associated with suspected heparin-induced thrombocytopenia. Nanwa N, Mittmann N, Knowles S, Bucci C, Selby R, Shear N, Walker SE, Geerts W. Pharmacoeconomics. 2011 Jun;29(6):511-20. doi: 10.2165/11584330-000000000-00000. PMID: 21473656 [PubMed - indexed for MEDLINE] 61. Inhaled anticholinergic drug therapy and t he risk of acute urinary retention in chronic obstructive pulmonary disease: a population-based study. Stephenson A, Seitz D, Bell CM, Gruneir A, Gershon AS, Austin PC, Fu L, Anderson GM, Rochon PA, Gill SS. Arch Intern Med. 2011 May 23;171(10):914-20. PMID: 21606096 [PubMed - indexed for MEDLINE] 62. Comparison of inhaled long-acting β-agonist and ant icholinergic effectiveness in older patients with chronic obstructive pulmonary disease: a c ohort study. Gershon A, Croxford R, To T, Stanbrook MB, Upshur R, Sanchez-Romeu P, Stukel T. Ann Intern Med. 2011 May 3;154(9):583-92. PMID: 21536937 [PubMed - indexed for MEDLINE] 63. Is cardiotoxicity being adequately assessed in current trials of cytotoxic and targeted agents in breast cancer? Verma S, Ewer MS. Ann Oncol. 2011 M ay;22(5):1011-8. Epub 2010 N ov 22. Review. PMID: 21097988 [PubMed - indexed for MEDLINE] 64. Fibrous cap enhancement in symptomatic atherosclerotic basilar artery stenosis. Vergouwen MD, Silver FL, Mandell DM, Mikulis DJ, Krings T, Swartz RH. Arch Neurol. 2011 May;68(5):676. No abstract available. PMID: 21555648 [PubMed - indexed for MEDLINE] 65. Patient and heal thcare professional factors influencing end-of-life decision-making during critical illness: a systematic review. Frost DW, Cook DJ, Heyland DK, Fowler RA. Crit Care Med. 2011 May;39(5):1174-89. Review. PMID: 21336127 [PubMed - indexed for MEDLINE] 66. Qualitative analysis of an intensive care unit family satisfaction survey. Henrich NJ, Dodek P, Heyland D, Cook D, Rocker G, Kutsogiannis D, Dale C, Fowler R, Ayas N. Crit Care Med. 2011 May;39(5):1000-5. PMID: 21283004 [PubMed - indexed for MEDLINE] 67. Patient adherence to aromatase inhibitor treatment in the adjuvant setting. Verma S, Madarnas Y, Sehdev S, Martin G, Bajcar J. Curr Oncol. 2011 May;18 Suppl 1:S3-9. PMID: 21698059 [PubMed]

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Selected Publications (cont’d) 68. Does user-centred design affect the efficiency, usability and safety of CPOE order sets? Chan J, Shojania KG, Easty AC, Etchells EE. J Am Med Inform Assoc. 2011 M ay 1;18(3):276-81. PMID: 21486886 [ PubMed indexed for MEDLINE] 69. Prospective study of breast cancer incidence in women with a B RCA1 or BRCA2 mutation under surveillance with and without magnetic resonance imaging. Warner E, Hill K, Causer P, Plewes D, Jong R, Yaffe M, Foulkes WD, Ghadirian P, Lynch H, Couch F, Wong J, Wright F, Sun P, Narod SA. J Clin Oncol. 2011 May 1;29(13):1664-9. Epub 2011 Mar 28.PMID: 21444874 [PubMed - indexed for MEDLINE] 70. Long-term follow-up of women in trials of adjuvant therapy for breast cancer: is it still important? Pritchard KI, Sousa B.J Clin Oncol. 2011 May 1;29(13):1651-2. Epub 2011 Mar 21. No abstract available. PMID:21422436 [PubMed - indexed for MEDLINE] 71. A population-based analysis of esophageal and gastric cardia adenocarcinomas in Ontario, Canada: incidence, risk factors, and regional variation. Tinmouth J, Green J, Ko YJ, Liu Y, Paszat L, Sutradhar R, Rabeneck L, Urbach D. J Gastrointest Surg. 2011 M ay;15(5):782-90. Epub 2011 Mar 16. PMID:21409602 [PubMed indexed for MEDLINE] 72. Evaluation of an inter-professional educational intervention to improve the use of arthritis best practices in primary care. Lineker SC, Bell MJ, Badley EM. J Rheumatol. 2011 May;38(5):931-7. Epub 2011 Feb 1. PMID: 21285165 [PubMed - indexed for MEDLINE] 73. Emerging targets and treatments in amyotrophic lateral sclerosis. Zinman L, Cudkowicz M. Lancet Neurol. 2011 May;10(5):481-90. Review. PMID: 21511200 [PubMed - indexed for MEDLINE] 74. Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group. Buckstein R, Kuruvilla J, Chua N, Lee C, Macdonald DA, Al-Tourah AJ, Foo AH, Walsh W, Ivy SP, Crump M, Eisenhauer EA. Leuk Lymphoma. 2011 May;52(5):833-41. Epub 2011 Apr 4. PMID:21463120[PubMed - indexed for MEDLINE] 75. Trends in the aggressiveness of end-of-life cancer care in the universal health care system of Ontario, Canada. Ho TH, Barbera L, Saskin R, Lu H, Neville BA, Earle CC. J Clin Oncol. 2011 Apr 20;29(12):1587-91. Epub 2011 Mar 14. PMID: 21402603 [PubMed - indexed for MEDLINE] 76. Impact of Subcortical Hyperintensities on Dual-tasking in Alzheimer Disease and Aging. Nadkarni NK, Levine B, McIlroy WE, Black SE. Alzheimer Dis Assoc Disord. 2011 Apr 14. [Epub ahead of print] PMID:21502852 [PubMed - as supplied by publisher] 77. Rescue percutaneous coronary interventions for failed fibrinolytic therapy in ST-segment elevation myocardial infarction: a population-based study. Ko DT, Atzema CL, Donovan LR, Graham MM, Huynh T, So DY, Wang J, Wijeysundera HC, Tu JV. Am Heart J. 2011 Apr;161(4):764-770.e1. PMID:21473977 [PubMed - indexed for MEDLINE] 78. Predictors of short-term complications after implantable cardioverter-defibrillator replacement: results from the Ontario ICD Database. Krahn AD, Lee DS, Birnie D, Healey JS, Crystal E, Dorian P, Simpson CS, Khaykin Y, Cameron D, Janmohamed A, Yee R, Austin PC, Chen Z, Hardy J, Tu JV; Ontario ICD Database Investigators. Circ Arrhythm Electrophysiol. 2011 Apr 1;4(2):136-42. Epub 2011 Feb 15.PMID:21325209 [PubMed - indexed for MEDLINE] 79. Luminal esophageal temperature monitoring with a deflectable esophageal temperature probe and intracardiac chocardiography may reduce esophageal injury during atrial fibrillation ablation procedures: results of a pi lot study. Leite LR, Santos SN, Maia H, Henz BD, Giuseppin F, Oliverira A, Zanatta AR, Peres AK, Novakoski C, Barreto JR, Vassalo F, d'Avila A, Singh SM. Circ Arrhythm Electrophysiol. 2011 Apr 1;4(2):149-56. Epub 2011 Feb 15. PMID: 21325208 [PubMed - indexed for MEDLINE] 80. Cardiovascular and r enal outcomes with telmisartan, ramipril, or both in people at high renal risk: results from the ONTARGET and TRANSCEND studies. Tobe SW, Clase CM, Gao P, McQueen M, Grosshennig A, Wang X, Teo KK, Yusuf S, Mann JF; ONTARGET and T RANSCEND Investigators. Circulation. 2011 M ar 15;123(10):1098-107. Epub 2011 Feb 28. PMID:21357827 [PubMed - indexed for MEDLINE] 81. Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia. Tomic J, Lichty B, Spaner DE. Blood. 2011 Mar 3;117(9):2668-80. Epub 2011 J an 4.PMID:21205928 [PubMed - indexed for MEDLINE] 82. Effect of subsequent pregnancies on the risk of developing diabetes following a first pregnancy complicated by gestational diabetes: a population-based study. Retnakaran R, Austin PC, Shah BR. Diabet Med. 2011 Mar;28(3):287-92. doi: 10.1111/j.1464-5491.2010.03179.x. PMID: 21309836 [PubMed - indexed for MEDLINE]

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Selected Publications (cont’d) 83. The psychological impact of being screened for anal cancer in HIV-infected men who have sex with men. Tinmouth J, Raboud J, Ali M, Malloch L, Su D, Sano M, Lytwyn A, Rourke SB, Rabeneck L, Salit I. Dis Colon Rectum. 2011 Mar;54(3):352-9. PMID: 21304309 [PubMed - indexed for MEDLINE] 84. Vascular cognitive impairment: epidemiology, subtypes, diagnosis and m anagement. Black SE. J R Coll Physicians Edinb. 2011 Mar;41(1):49-56. Review. PMID: 21365068 [PubMed - indexed for MEDLINE] 85. Effectiveness of the P.A.R.T.Y. (Prevent Alcohol and Risk-related Trauma in Youth) program in preventing traumatic injuries: a 10 -year analysis. Banfield JM, Gomez M, Kiss A, Redelmeier DA, Brenneman F. J Trauma. 2011 Mar;70(3):732-5. PMID: 21610366[PubMed - indexed for MEDLINE] 86. Predicting the risk of 1-year mortality in incident dialysis patients: accounting for case-mix severity in studies using administrative data. Quinn RR, Laupacis A, Hux JE, Oliver MJ, Austin PC.Med Care. 2011 Mar;49(3):257-66.PMID:21301370 [PubMed - indexed for MEDLINE] 87. The relationship between indoleamine 2,3-dioxygenase activity and post-stroke cognitive impairment.Gold AB, Herrmann N, Swardfager W, Black SE, Aviv RI, Tennen G, Kiss A, Lanctôt KL. J Neuroinflammation. 2011 Feb 16;8:17. PMID: 21324164 [PubMed - indexed for MEDLINE] 88. Comparison of the effectiveness and safety of low-molecular weight heparin versus unfractionated heparin anticoagulation after heart valve surgery. Bucci C, Geerts WH, Sinclair A, Fremes SE. Am J Cardiol. 2011 Feb 15;107(4):591-4. Epub 2010 Dec 22. PMID: 21184996 [PubMed - indexed for MEDLINE] 89. Conventional versus automated measurement of blood pressure in primary care patients with systolic hypertension: randomised parallel design controlled trial. Myers MG, Godwin M, Dawes M, Kiss A, Tobe SW, Grant FC, Kaczorowski J. BMJ. 2011 Feb 7;342:d286. doi: 10.1136/bmj.d286. PMID: 21300709 [PubMed indexed for MEDLINE] 90. Preoperative stereotactic body radiotherapy to a s kull renal cell metastasis: an al ternative to preoperative embolization? Mitera G, Bjarnason GA, Pirouzmand F, Bilbao J, Danjoux C, Sahgal A. J Palliat Med. 2011 Feb;14(2):157-60. Epub 2011 Jan 12. PMID: 21226619 [PubMed - indexed for MEDLINE] 91. Impact of MRI surveillance and breast cancer detection in young women with BRCA mutations. Warner E. Ann Oncol. 2011 Jan;22 Suppl 1:i44-9. PMID: 21285150 [PubMed - indexed for MEDLINE] 92. Improvement in DCIS detection rates by MRI over time in a high-risk breast screening study. Warner E, Causer PA, Wong JW, Wright FC, Jong RA, Hill KA, Messner SJ, Yaffe MJ, Narod SA, Plewes DB. Breast J. 2011 JanFeb;17(1):9-17. doi: 10.1111/j.1524-4741.2010.01018.x. PMID: 21251121 [PubMed - indexed for MEDLINE] 93. A qualitative evaluation of strategies to increase colorectal cancer screening uptake. Tinmouth J, Ritvo P, McGregor SE, Claus D, Pasut G, Myers RE, Guglietti C, Paszat LF, Hilsden RJ, Rabeneck L. Can Fam Physician. 2011 Jan;57(1):e7-15. PMID: 21322288 [PubMed - in process] 94. Complexity of MRI white matter hyperintensity assessments in relation to cognition in aging and dementia from the Sunnybrook Dementia Study. Gao FQ, Swartz RH, Scheltens P, Leibovitch FS, Kiss A, Honjo K, Black SE. J Alzheimers Dis. 2011;26 Suppl 3:379-88. PMID: 21971477 [PubMed - in process] 95. Tumors that acquire resistance to low-dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose cyclophosphamide. Emmenegger U, Francia G, Chow A, Shaked Y, Kouri A, Man S, Kerbel RS. Neoplasia. 2011 Jan;13(1):40-8. PMID: 21245939 [PubMed - indexed for MEDLINE] 96. Impact of new chemotherapeutic and targeted agents on survival in stage IV non-small cell lung cancer. Yu JL, Simmons C, Victor JC, Han D, Hogeveen S, Leighl N, Verma S. Oncologist. 2011;16(9):1307-15. Epub 2011 Aug 11. PMID: 21835896 [PubMed - in process] 97. Early breast cancer in the older woman. Gandhi S, Verma S. Oncologist. 2011;16(4):479-85. Epub 2011 Mar 17. Review. PMID: 21415085 [PubMed - indexed for MEDLINE] 98. In the end what matters most? A review of clinical endpoints in advanced breast cancer. Verma S, McLeod D, Batist G, Robidoux A, Martins IR, Mackey JR. Oncologist. 2011;16(1):25-35. Epub 2011 Jan 6. Review. PMID: 21212428 [PubMed - indexed for MEDLINE] 99. The kidney in normal pregnancy and preeclampsia. Cornelis T, Odutayo A, Keunen J, Hladunewich M. Semin Nephrol. 2011 Jan;31(1):4-14. Review. PMID: 21266261 [PubMed - indexed for MEDLINE] 100. The safety of proton pump inhibitors and clopidogrel in patients after stroke. Juurlink DN, Gomes T, Mamdani MM, Gladstone DJ, Kapral MK. Stroke. 2011 Jan;42(1):128-32. Epub 2010 Dec 16. PMID: 21164123 [PubMed - indexed for MEDLINE] 101. Do selective serotonin receptor inhibitor antidepressants reduce tamoxifen's effectiveness and increase the risk of death from breast cancer? Pritchard KI. Breast Cancer Res. 2010 D ec 20;12 Suppl 4:S18. No abstract available. PMID: 21172080 [PubMed - indexed for MEDLINE]

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Grants Cardiology Dr. Eugene Crystal: − MI POP grant $50,000 CAD (PI Crystal) Dr. Jack Tu: − Apr 2011–Mar 2014 Austin P, Anderson G, TU JV (Co-Inv). Statistical Methods for Health Services Research. Canadian Institutes of Health Research Operating Grant. Total: $122,994. Drs. Jack Tu & Harindra Wijeysundera: − Apr 2011–Mar 2015 TU JV (PI), Atzema C, Austin P, Cox, J, Huynh T, Jackevicius C, Ko D, Lambert L, Lee DS, Natarajan M, So D, Stukel T, Wijeysundera H. Measuring and improving the quality of ST-segment elevation myocardial infarction (STEMI) care. Canadian Institutes of Health Research Operating Grant – MOP 111035. Total: $995,920. Drs. Jack Tu & Eugene Crystal: − Apr 2011–Mar 2015 Lee DS, Austin P, Birnie D, Cameron D, Crystal E, Dorian P, Harris L, Healey J, Khaykin Y, Krahn A, Mangat I, Simpson C, TU JV (Co-Inv), Yee R. Implantable Cardioverter Defibrillator Selection to Improve Survival in Left Ventricular Systolic Dysfunction: ISIS LVSD Study (Ontario ICD Database Phase 2). Canadian Institutes of Health Research Operating Grant – MOP 111150. Total: $589,044. General Internal Medicine Dr. Ayelet Kuper: − Knowledge Production Practices and Legitimization Strategies Used by Social Scientists and Humanities Scholars Working in Faculties of Medicine. Social Sciences and Humanities Research Council of Canada (SSHRC) Standard Operating Grant. PI: Mathieu Albert. Co-I: Ayelet Kuper. $51,900. April 2011 – March 2014. Medical Oncology & Haematology Dr. Urban Emmenegger: − Prostate Cancer Canada, Emmenegger (PI), 01/07/2011 - 30/06/2013 Overcoming resistance to systemic prostate cancer therapy by autophagy modulation. Studies aiming at characterizing the postulated differential impact of autophagy on metronomic (i.e., chronic) versus conventional (i.e., intermittent) chemotherapy using a number of prostate cancer models $ 120,000

− Cancer Research Society Emmenegger 01/09/2011 - 31/08/2013 Studying autophagy as a complementary

therapeutic target in antivascular tumor therapy Studies aiming at defining the role of autophagy inhibition during antiangiogenic versus antivascular therapy $ 120,000 Dr. Teresa Petrella: − Received an MRA Team grant as Co-Pi: Alan Spatz, MD, Jewish General Hospital/Lady Davis Institute for Medical Research; Teresa Petrella, MD, Sunnybrook Health Sciences Centre; Joos van den Oord, MD, PhD, Katholieke Universiteit Leuven; Leon Van Kempen, PhD, McGill University; and Boris Bastian, MD, PhD, Memorial Sloan-Kettering Cancer Center, for studying X chromosome genes as potential prognostic biomarkers and therapeutic targets, building on the observation that women with melanoma have a better prognosis than men. Neurology Dr. Mario Masellis: − PI: MASELLIS, Mario – Parkinson’s-related dementia: A pharmacogenomic study of cholinesterase inhibitors investigating cognitive benefit, motor worsening and brain SPECT Funded: Parkinson’s Society Canada, New Investigator Award (Operating Grant)Funding period: September 1, 2011 – August 31, 2013 Amount: $90,000 Respirology & Clinical Immunology Dr. Andrea Gershon: − Andrea Gershon (PI), Shawn Aaron, Teresa To, Impact of pulmonary function testing on health outcomes of individuals with chronic obstructive pulmonary disease. Ontario Lung Association, $50,000, 1 year.

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Department Notices DOM Partnership Meeting Monday November 21, 5:00-7:00pm, EG61-McLaughlin Lecture Theatre DOM Annual Holiday Drop-in Tuesday December 13, 12:00 – 1:30pm, Blythwood Room, HG15 U of T Internal Grant Review Service The service is directed specifically for junior faculty members at the Assistant and Lecturer ranks. It is a non-threatening review of your grant designed to help improve your odds of getting funded. All you need to do is have your grant prepared 30 days prior to the submission date to allow time for the review. As you prepare your grant, talk to your University Division Director (ie at least 6 weeks before the grant deadline). They will help you choose 2 reviewers. For more information go to the DOM web site. http://www.deptmedicine.utoronto.ca/Research/internalgrant.htm You can also call Conrad Liles (416 340 3183) [email protected], Professor and Vice Chair of Medicine who has created this program. Or contact Rob Fowler at Sunnybrook x 7471, [email protected]. Research Assistant for Education Projects The department has a part-time Research Assistant to assist with Education projects. Elisa Hollenberg has been working with us since October of 2010 and she has been integral in the completing of several research projects since then. She has already worked with 5 different staff in our department on various tasks including literature reviews, REB applications and data entry. Elisa has particular experience in qualitative research but is available to help in any education related project. Elisa is currently working part time, 2 days per week and can be reached at: [email protected] with any request.

Department of Medicine Sunnybrook Health Sciences Centre 2075 Bayview Ave Suite D4-74 Toronto Ontario M4N 3M5 Phone: 416-480-4592 Fax: 416-480-6191 Email: [email protected] Fully affiliated with the University of Toronto

For questions, comments and submissions, please contact Denise Campbell [email protected] or 416-480-6100 x2007