Eva LATORRE DUQUE
Curriculum Vitae PERSONAL INFORMATION Surname(s): Name: Sex: Email address: ORCID:
LATORRE DUQUE EVA Female
[email protected] orcid.org/0000-0002-5797-3909
Name of the entity Department: Category: Start date Type of dedication:
University of Exeter Medical School Associate Research Fellow 14/09/2015 Full time
CURRENT PROFESSIONAL SITUATION
UNIVERSITY EDUCATION
PhD “Relationship between the intestinal serotoninergic and the innate immune systems: Implications in Chronic Inflammatory Bowel Disease” University of Zaragoza, Spain. Date: April 2015. Doctorate Special Award from Zaragoza University Master Degree in Introduction to Veterinary Science Research – Basic Biomedical Sciences University of Zaragoza, Spain. Date: September 2010.
Degree in Veterinary Medicine. University of Zaragoza, Spain. Date: June 2009
PERSONAL SKILLS Mother tongue(s)
Spanish
OTHER LANGUAGE(S)
English UNDERSTANDING
SPEAKING
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Reading
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WRITING
Spoken interaction Spoken production
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Eva LATORRE DUQUE
Curriculum Vitae
Italian UNDERSTANDING
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A2
WRITING
Spoken interaction Spoken production
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RESEARCH PROJECTSs Name of the project: "The role of age-associated inflammation in moderation of alternative splicing and its impact on age-related disease” Funding body: Dunhill Medical trust Start date: September 2015, 36 months Head researcher: Dr. Lorna Harries
Name of the project: "Gastrointestinal Pathophysiology" Consolidated Group. (Ref.: B61). Funding body: Aragon Government Number of participating research: 10 Start date: January 2015, 12 months Head researcher: Dr. José Emilio Mesonero
Name of the project: "Gastrointestinal Pathophysiology" Consolidated Group. (Ref.: B61). Funding body: Aragon Government Number of participating research: 12 Start date: January 2014, 12 months Head researcher: Dr. José Emilio Mesonero
Name of the project: "Gastrointestinal Pathophysiology" Consolidated Group. (Ref.: B61). Funding body: Aragon Government Number of participating research: 15 Start date: January 2013, 12 months Head researcher: Dr. Miguel Angel Plaza
Name of the project: Pathophysiology in chronic inflammatory bowel diseases. (Ref.: 2012/0567) Funding body: ARAINF Foundation (Aragon’s Foundation for the study and support inflammatory disease) Number of participating research: 4 Start date: December 2012, 1 month Head researcher: Dr. Ana Isabel Alcalde
Name of the project: "Gastrointestinal Pathophysiology" Consolidated Group. (Ref.: B61). Funding body: Aragon Government Number of participating research: 15 Start date: January 2012, 12 months Head researcher: Dr. Miguel Angel Plaza
Name of the project: Interaction between TLRs system / NOD and the serotonergic system and its role in intestinal physiology. Alterations in inflammatory processes (Ref.: BFU2010-18971). Funding body: Ministry of Science and Innovation. Spanish Government Number of participating research: 8 Start date: January 2010, 36 months Head researcher: Dr. Ana Isabel Alcalde
PUBLICATIONS Forcén R, Latorre E, Pardo J, Alcalde AI, Murillo MD, Grasa L. “Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved”. Neurogastroenterol Motil. 2015. 27, 1258–1266 Grasa L, Abecia L, Forcén R, Castro M, García de Jalón JA, Latorre E, Alcalde AI, Murillo MD. "Antibiotic-induced depletion of murine microbiota induces mild inflammation and changes in toll-like receptor patterns and intestinal motility” Microbial Ecology (2015) DOI: 10.1007/s00248-015-0613-8 Eva Latorre, Nyurky Matheus, Elena Layunta, Ana Isabel Alcalde and José E. Mesonero. “IL-10 counteracts proinflammatory mediator evoked oxidative stress in Caco-2 cells. Mediators of Inflammation, vol 2014, Article ID 982639, 6 pages. Doi: 10.1155/2014/982639. Eva Latorre, Carmen Mandoza, Elena Layunta, Ana I. Alcalde and José E. Mesonero. “TLR2, TLR3, and TLR4 Activation Specifically Alters the Oxidative Status of Intestinal Epithelial Cells” Cell Stress and Chaperones. 2013. DOI 10.1007/s12192-013-0461-8 Latorre E, Mendoza C, Matheus N, Castro M, Grasa L, Mesonero JE, Alcalde AI.
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“IL-10 modulates SERT activity and molecular expression in intestinal epithelial cells” Cytokine. 2013;61:778–784 Eva Latorre, Ana I Alcalde, Jose E Mesonero. [Implication of serotonin transporter (SERT) in intestinal inflammatory diseases]. Revista de la Sociedad Española de Ciencias Fisiológicas (SECF). 2013;15(2):5-8. [Journal of Spanish Society of Physiology Sciences] Mendoza C, Matheus N, Latorre E, Castro M, Mesonero JE, Alcalde AI. “Toll-like receptor 3 activation affects serotonin transporter activity and expression in human enterocytelike Caco-2 cells Cellular Physiology and Biochemistry.2012;30(1):187-198. Mesonero JE, Latorre E, Mendoza C, Matheus N, Alcalde AI. [Role of the serotonergic system in the intestinal pathophysiology] Gaceta de Ciencias Veterinarias (UCLA-Venezuela). 2012;15 (2):72-79. [Journal of Veterinary Sciences- Centroccidental University "Lisandro Alvarado” Venezuela] Published Abstracts: Latorre E, Pradilla A, Chueca B, Pagán R, Layunta E, Mesonero JE, Alcalde AI. Listeria monocytogenes affects serotonin transporter activity and expression in human intestinal epithelial cells by TLR10 activation”. United European Gastroenterology Journal 3 (5 Suppl.): A311. (2015) Layunta E, Latorre E, Grasa L, Castro M, Pardo J, Gomollón F, Alcalde AI, Mesonero JE. “NOD1 and NOD2 interact with serotonin transporter and Toll-like receptors in intestinal epithelial cells. Analysis in intestinal tract from mice colitis model”. United European Gastroenterology Journal 3 (5 Suppl.): A312A313. (2015) Layunta E, Latorre E, Gimeno A, Grasa L, Castro M, Plaza MA, Pardo J, Gomollón F, Alcalde AI, Mesonero JE. “Toll-like Receptor 9 activation affects intestinal serotonin transporter activity and expression in Caco-2 cells”. Acta Physiol. 2015, 214 (Suppl. 701) Grasa L, Nevado R, Forcen R, Layunta E, Latorre E, Alcalde AI, Murillo MD. “The depletion of murine microbiota by bacitracin and neomycin reduces the intestinal permeability by increasing the levels of ZO1, JAM-A and Occludin”. United European Gastroenterology Journal 3 (5 Suppl.): A314. (2015) Layunta E, Latorre E, Grasa L, Castro M, Plaza MA, Pardo J, Santiago L, Sánchez de Medina F, Martínez-Augustin O, Ocón B, Aranda, C, Mesonero JE, Alcalde AI. “Expression of microbiota recognition receptors and intestinal serotoninergic system in two mouse models of colitis”. Acta Physiol. 2015, 214 (Suppl. 701) Latorre E, Layunta E, Gimeno A, Grasa L, Castro M, García S, Gros B, Arruebo MP, Alcalde AI, Mesonero JE. “Oxidative stress balance between pro- and anti-inflammatory factors in human intestinal epithelial cells”. Acta Physiol. 2015, 214 (Suppl. 701) E Latorre, E Layunta, M Castro, L Grasa, J Pardo, JE Mesonero, AI Alcalde. “Interleukin-10 expression is regulated by Toll like receptors 2 and 4 in intestinal epithelium”. United European Gastroenterology Journal, 2(1 Suppl.):P1145. (2014). R Forcén, E Latorre, J Pardo, AI Alcalde, MD Murillo, L Grasa. “Effect of Toll-like receptors 2 and 4 on the serotonin induced motor response mediated by 5-HT2 and 5-HT3 receptors in mouse ileum”. United European Gastroenterology Journal, 2(1 Suppl.):P0968. (2014). L Grasa, M Castro, E Latorre, E Layunta, S Gonzalo, A Gimeno, JE Mesonero, MP Arruebo, MA Plaza, AI Alcalde, MD Murillo. “Depletion of murine intestinal microbiota by antibiotics: Effects on gut transit and Toll-Like receptors expression. United European Gastroenterology Journal, 1(1 Suppl.):A392. (2013). E. Latorre, E Layunta, A. Gimeno, L. Grasa, M. Castro, J. Pardo, M.A. Plaza, J.E. Mesonero, A.I. Alcalde. “Activation of TLR2 affects intestinal serotonin transporter expression”. Journal of Physiology and Biochemistry, 69(3): 664. (2013). E Latorre, E Layunta, A. Gimeno, L. Grasa, M. Castro, S. García, B. Gros, M.A. Plaza, J.E. Mesonero, A.I. Alcalde. TLR2, TLR3 and TLR4 activation induces cellular oxidative damage in Caco-2 cells. Poster
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selected for the Submission of the Week on the F1000 Posters home page the week 13-19 May 2013 (http://f1000.com/posters) Journal of Physiology and Biochemistry, 69(3): 665. (2013). Gimeno A, Castro M, Martínez LF, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Murillo MD, Arruebo MP, Plaza MA. Role of COX-2 from brain perivascular macrophages in the initiation of gastrointestinal (GI) motor disturbances and fever induced by LPS in sheep. Acta Physiologica, 206 (Suppl. 693): P244. (2012). Plaza MA, Gimeno A, Castro M, Martínez LF, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Arruebo MP, Murillo MD. Early gastrointestinal motor disturbances induced by Lipopolysaccharide (LPS) in sheep may be initiated through activation of COX-2 in pulmonary and hepatic macrophages. Neurogastroenterology & Motility, 24(Suppl. 2): 82. (2012). Plaza MA, Gimeno A, Castro M, Martínez LF, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Arruebo MP, Murillo MD. Involvement of COX-2 derived from cerebral perivascular macrophages in the early gastrointestinal motor disturbances induced by Lipopolysaccharide (LPS) in sheep. Neurogastroenterology & Motility, 24(Suppl. 2): 143-144. (2012). Grasa L, Murillo MD, Alcalde AI, Pardo J, Latorre E, Mesonero JE, Arruebo MP, Plaza MA, Gonzalo S. Role of Toll-like receptors 2 and 4 in the serotonin-induced responses in mouse ileum and colon. Neurogastroenterology & Motility, 24(Suppl. 2): 149-150. (2012). E. Latorre, E. Layunta, L. Grasa, M. Castro, A. Gimeno, M.A. Plaza, F. Gomollón, S. García, B. Gros, J.E. Mesonero, A.I. Alcalde. “Interleukin-10 reverses the oxidative damage induced by serotonin and TNF-alpha in human enterocyte-like Caco-2 cells” Acta Physiologica, 206 (Suppl 693): P103. (2012) E. Latorre, C. Mendoza, N. Matheus, M. Castro, L. Grasa, A. Gimeno, M. A. Plaza, F. Gomollón, J. E. Mesonero & A. I. Alcalde. “TLR3 and TLR4 activation and pro-inflammatory factors induce oxidative damage in enterocyte-like Caco-2 cells” Acta Physiologica, 206 (Suppl 693): P7. (2012) Matheus N, Mendoza C, Iceta R, Latorre E, Mesonero JE, Alcalde AI. Inhibición de la recaptación de serotonina por efecto de tratamiento crónico con melatonina [Inhibition of serotonin reuptake by melatonin chronic treatment]. Acta Científica Venezolana, 62(Suppl. 1): 58. (2011). Mendoza C, Matheus N, Iceta R, Latorre E, Mesonero JE, Alcalde AI. Efecto de la activación del TLR4 en la función y expresión molecular de SERT [Effect of TLR4 activation on function and molecular expression of SERT]. Acta Científica Venezolana, 62(Suppl. 1): 58-59. (2011). Latorre E, Mendoza, Matheus N, Iceta R, Mesonero JE, Gros B, García S, Gomollón F, Alcalde AI. Modulación del transportador de serotonina (SERT) a través de factores antiinflamatorios [Modulation of serotonin transporter (SERT) through anti-inflammatory factors]. Archivos de la Facultad de Medicina de Zaragoza, 51(1): 44. (2011). Matheus N, Mendoza C, Iceta R, Latorre E, Mesonero JE, Plaza MA, Arruebo MP, Murillo D, Castro M, Grasa L, Alcalde AI. Melatonin effect on serotonin transporter in Caco-2 cells. Genes & Nutrition, 5(Suppl. 1): 23-24. (2010). Matheus N, Mendoza C, Iceta R, Latorre E Mesonero JE, Alcalde AI. Inhibición de la recaptación de serotonina en procesos inflamatorios [Serotonin reuptake inhibition in inflammatory processes]. Archivos de la Facultad de Medicina de Zaragoza, 49(3): 13. (2009).
CONGRESS COMMUNICATIONS Grasa L, Forcén R, Latorre E, Pardo J, Alcalde AI, Murillo MD. “Los receptores tipo Toll 2 y 4 modulan de forma opuesta la respuesta contráctil inducida por la serotonina en el colon de ratón: papel de los receptores de serotonina”. Type of participation: Oral Communication.
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Congress: XXIII Reunión del grupo español de motilidad digestiva. Madrid 20-21 November 2015. Latorre E, Pradilla A, Chueca B, Pagán R, Layunta E, Mesonero JE, Alcalde AI. “Listeria monocytogenes affects serotonin transporter activity and expression in human intestinal epithelial cells by TLR10 activation”. Type of participation: Poster Congress: 23rd United European Gastroenterology Week (UEG Week). Barcelona (Spain), 24-28 October 2015. Layunta E, Latorre E, Grasa L, Castro M, Pardo J, Gomollón F, Alcalde AI, Mesonero JE. “NOD1 and NOD2 interact with serotonin transporter and Toll-like receptors in intestinal epithelial cells. Analysis in intestinal tract from mice colitis model” Type of participation: Poster Congress: 23rd United European Gastroenterology Week (UEG Week). Barcelona (Spain), 24-28 October 2015.
Grasa L, Nevado R, Forcen R, Layunta E, Latorre E, Alcalde AI, Murillo MD. “The depletion of murine microbiota by bacitracin and neomycin reduces the intestinal permeability by increasing the levels of ZO1, JAM-A and Occludin” Type of participation: Poster Congress: 23rd United European Gastroenterology Week (UEG Week). Barcelona (Spain), 24-28 October 2015. E. Latorre, A. Pradilla, B. Chueca, R Pagán, E. Layunta, J.E. Mesonero, A.I. Alcalde. [Listeria monocytogenes inhibits intestinal serotonin transporter (SERT) through TLR10] Type of participation: Oral communication. Congress: XXXVIII Congreso de la Sociedad Española de Bioquímica y Biología Molecular. Valencia (Spain), 7-10 September 2015. A. Pardillos, E. Arruebo, P. Corsino, E. Latorre, E. Layunta, A. Alcalde. [Transcriptional genetic signature of the intestinal mucosa of ulcerative colitis patients versus healthy controls: Analysis and preliminary studies] Type of participation: Oral communication awarded as the best communication of the meeting Congress: XXIV Reunión científica de la Sociedad Aragonesa de patología digestiva. Zaragoza (Spain) 20-21 November 2014 [Meeting of Aragon Society of digestive pathology] R. Forcén, E. Latorre, J. Pardo, M. Castro, M.P. Arruebo, M.A. Plaza, A.I. Alcalde, M.D. Murillo, L. Grasa. [Toll-like receptor 2 and 4 modulate the expression and activity of 5-HT2 and 5-HT3 receptors on mice ileum] Type of participation: Oral communication Congress: XXII Reunión del grupo español de motilidad digestiva. Barcelona (Spain), 21-22 November 2014. [Meeting of Spanish Group of Motility] Castro, M., Murillo, E., Plaza, M.A., Grasa, L., Murillo, M.D., Layunta, E., Latorre, E., Arruebo, M.P. [Effect of intracolonic activation of TRPV2 receptor on colon distal motility in a mice model]. Type of participation: Poster Congress: XXII Reunión del grupo español de motilidad digestiva. Barcelona (Spain), 21-22 November 2014. [Meeting of Spanish Group of Motility] E. Latorre, E. Layunta, M. Castro, L. Grasa, J. Pardo, J.E. Mesonero, A. I. Alcalde. “Interleukin-10 expression is regulated by Toll like receptors 2 and 4 in intestinal epithelium”. Type of participation: Poster Congress: 22nd United European Gastroenterology week. Vienna (Austria), 18-22 October 2014. R. Forcén, E. Latorre, J. Pardo, A. I. Alcalde, M.D. Murillo, L. Grasa. “Effect of Toll-like receptors 2 and 4 on the serotonin induced motor response mediated by 5-HT2 and 5-HT3 receptors in mouse ileum”. Type of participation: Poster Congress: 22nd United European Gastroenterology week. Vienna (Austria), 18-22 October 2014. Latorre E, Layunta E, Gimeno A, Grasa L, Castro M, García S, Gros B, Arruebo MP, Alcalde AI Mesonero JE. “Oxidative stress balance pro- and anti-inflammatory factors in human intestinal epithelial cells”. Type of participation: Oral communication Congress: 26th Congress of the European Intestinal Transport Group (EITG). Marstrands (Sweden), 2-5 October 2014.
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Layunta E, Latorre E, Grasa L, Castro M, Plaza MA, Pardo J, Santiago L, Sánchez de Medina F, Martínez-Augustin O, Ocón B, Aranda C, Mesonero JE, Alcalde AI. “Expression of microbiota recognition receptors and intestinal serotoninergic system in two mouse models of colitis”. Type of participation: Oral communication Congress: 26th Congress of the European Intestinal Transport Group (EITG). Marstrands (Sweden), 2-5 October 2014. Layunta E, Latorre E, Gimeno A, Grasa L, Castro M, Plaza MA, Pardo J, Gomollón F, Alcalde AI, Mesonero JE. “Toll-like Receptor 9 activation affects intestinal serotonin transporter activity and expression in Caco-2 cells”. Type of participation: Oral communication Congress: 26th Congress of the European Intestinal Transport Group (EITG). Marstrands (Sweden), 2-5 October 2014. V. Caputi, I. Marsilio, E. Latorre Duque, S. Banzato, G. Tafuro, G. Orso, M.C. Giron. “Depletion of the gut microbiota affects the structure and the function of the enteric nervous system in mice. Type of participation: Poster Congress: Seminario Nazionale Dottorandi ed Assegnisti in Farmacologia ed affini. Rimini (Italy) 16-18 September 2014. [National Seminar of Fellows and PhD students in Pharmacology] L. Grasa, M. Castro, E. Latorre, E. Layunta, S. Gonzalo, J.E. Mesonero, M.P. Arruebo, M.A. Plaza, A.I. Alcalde, M.D. Murillo. [Deplection of intestinal microbiota by antibiotics induces slowing of intestinal transit and changes in the expression of Toll-like receptors in mouse] Type of participation: Oral communication Congress: XXI Reunión del grupo español de motilidad digestiva. Valencia (Spain) 29-30 November 2013. [Meeting of Spanish Group of Motility] Matheus N, Mendoza C, Latorre E, Iceta R, Mesonero JE, Alcalde AI. [Effect of adenosine on oxidative stress in epithelial cells during intestinal inflammatory processes] Type of participation: Poster Congress: LXIII Convención Anual de la Asociación Venezolana para el avance de la Ciencia (AsoVAC). Valencia (Venezuela) 24-29 November 2013. [LXIII Annual Convention of the Venezuelan Association for the Advancement of Science] L Grasa, M Castro, E Latorre, E Layunta, S Gonzalo, A Gimeno, MJ Mesonero JE, MP Arruebo, MA Plaza, AI Alcalde. “Depletion of murine intestinal microbiota by antibiotics: Effects on gut transit and TollLike receptors expression”. Type of participation: Poster awarded as “Poster of Excellence” Congress: 21st United European Gastroenterology (UEG) Week 2013. Berlin, Germany, 12-16 October 2013. Latorre E, Layunta E, Gimeno A, Grasa L, Castro M, Pardo J, Plaza MA, Mesonero JE, Alcalde AI. “Activation of TLR2 affects intestinal serotonin transporter expression”. Type of participation: Oral communication Congress: 25th Congress of the European Intestinal Transport Group (EITG). Bad Herrenalb (Germany), 11-14 April 2013. Latorre E, Layunta E, Gimeno A, Grasa L, Castro M, García S, Gros B, Plaza MA, Mesonero JE, Alcalde AI. “TLR2, TLR3 and TLR4 activation induces cellular oxidative damage in Caco-2 cells”. Type of participation: Poster Congress: 25th Congress of the European Intestinal Transport Group (EITG). Bad Herrenalb (Germany), 11-14 April 2013. E Layunta, E. Latorre, J.E. Mesonero, A. Gimeno, L. Grasa, M. Castro, M.A. Plaza, A.I. Alcalde. “Expression of TLR2, NOD1 and NOD2 in intestinal epithelial cells and its effect on serotonin transporter” Type of participation: Poster Congress: 4th Symposium on Veterinary Sciences Toulouse-München-Zaragoza. Toulouse (France), 1113 April 2013. Latorre E, Layunta E, Gimeno A, Castro M, Grasa L, Arruebo MP, Murillo MD, Plaza MA, Mesonero JE, Alcalde AI. [Study of the effect of inhibitors of the serotonin transporter on cellular oxidative damage]. Type of participation: Oral communication Congress: VIII Meeting of Neurosciences. Neuroscience health: An integrative perspective. Zaragoza
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(Spain). 21-22 November 2012 Gimeno A, Castro M, Mendoza AG, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Arruebo MP, Murillo MD, Plaza MA. [Role of cyclooxygenase-2 (COX-2) from brain perivascular macrophages in gastrointestinal motor alterations and fever induced by lipopolysaccharide in sheep]. Type of participation: Oral communication Congress: VIII Meeting of Neurosciences. Neuroscience health: An integrative perspective. Zaragoza (Spain). 21-22 November 2012 Latorre E, Layunta E, Grasa L, Castro M, Gimeno A, Plaza MA, García S, Gros B, Mesonero JE, Alcalde AI. “Interleukin-10 reverses the oxidative damage induced by serotonin and TNF-alpha in human enterocyte-like Caco-2 cells”. Type of participation: Poster Congress: Joint FEPS & Spanish Physiological Society Scientific Congress 2012. Santiago de Compostela (Spain). 8-11 September 2012 Latorre E, Mendoza C, Matheus N, Castro M, Grasa L, Gimeno A, Plaza MA, Gomollón F, Mesonero JE, Alcalde AI. “TLR3 and TLR4 activation and pro-inflammatory factors induced oxidative damage in enterocyte-like Caco-2 cells”. Type of participation: Poster Congress: Joint FEPS & Spanish Physiological Society Scientific Congress 2012. Santiago de Compostela (Spain). 8-11 September 2012 Gimeno A, Castro M, Martínez LF, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Murillo MD, Arruebo MP, Plaza MA. “Role of COX-2 from brain perivascular macrophages in the initiation of gastrointestinal (GI) motor disturbances and fever induced by LPS in sheep”. Type of participation: Poster Congress: Joint FEPS & Spanish Physiological Society Scientific Congress 2012. Santiago de Compostela (Spain). 8-11 September 2012 Plaza MA, Gimeno A, Castro M, Martínez LF, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Arruebo MP, Murillo MD. “Involvement of COX-2 derived from cerebral perivascular macrophages in the early gastrointestinal disturbances induced by lipopolysaccharide (LPS) in sheep”. Type of participation: Poster Congress: 5th Joint International Neurogastroenterology and Motility Meeting. Bologna (Italy), 6-8 September 2012. Plaza MA, Gimeno A, Castro M, Martinez LF, Latorre E, Grasa L, Alcalde AI, Mesonero JE, Arruebo MP, Murillo MD. “Early gastrointestinal disturbances induced by lipopolysaccharide (LPS) in sheep may be initiated through activation of COX-2 in pulmonary and hepatic macrophages”. Type of participation: Poster Congress: 5th Joint International Neurogastroenterology and Motility Meeting. Bologna (Italy), 6-8 September 2012. Grasa L, Murillo MD, Alcalde AI, Pardo J, Latorre E, Mesonero JE, Arruebo MP, Plaza MA, Gonzalo S. “Role of toll-like receptors 2 and 4 in the serotonin-induced responses in mouse ileum and colon”. Type of participation: Poster Congress: 5th Joint International Neurogastroenterology and Motility Meeting. Bologna (Italy), 6-8 September 2012. Latorre E, Mendoza C, Matheus N, Castro M, Grasa L, Gimeno A, Plaza MA, Mesonero JE, Alcalde AI. “Modulation of serotonin transporter activity under inflammatory conditions”. Type of participation: Oral communication Congress: V International Conference BIFI (Institute for Biocomputation and Physics of Complex Systems2012 – Protein Targets: Discovery of bioactive compounds. Zaragoza (Spain). 1-4 February 2012 Matheus N, Mendoza C, Iceta R, Latorre E, Mesonero JE, Alcalde AI. [Inhibition of serotonin reuptake by melatonin chronic treatment] Type of participation: Oral communication Congress: LXI Annual Convention of the Venezuelan Association for the Advancement of Science (AsoVAC). Maracay (Venezuela). 13-18 November 2011. Mendoza C, Matheus N, Iceta R, Latorre E, Mesonero JE, Alcalde AI. [Effect of TLR4 activation on function and molecular expression of SERT].
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Type of participation: Oral communication Congress: LXI Annual Convention of the Venezuelan Association for the Advancement of Science (AsoVAC). Maracay (Venezuela). 13-18 November 2011. Latorre E, Castro M, Grasa M, García S, Gros B, Vicente R, Gomollón, Mesonero JE, Alcalde AI. [IL-10 enhances serotonin uptake in Caco-2 cells]. Type of participation: Oral communication Congress: XXXIV Congress of the Spanish Society of Biochemistry and Molecular Biology (SEBBM). Barcelona (Spain). 5-8 September 2011 Grasa L, Hernández LV, Gonzalo S, Castro M, Gimeno A, Latorre E, Alcalde AI, Arruebo MP, Plaza MA, Murillo MD. [The lipopolysaccharide from E. coli induces activation of NF-ĸB and expression of IL-6 and TNF-α in the small intestine of rabbit]. Type of participation: Poster Congress: XXXIV Congress of the Spanish Society of Biochemistry and Molecular Biology (SEBBM). Barcelona (Spain). 5-8 September 2011 Latorre E, Mendoza C, Matheus N, Iceta R, Mesonero JE, Gros B, García S, Vicente R, Gomollón F, Alcalde AI. [Modulation of the serotonin transporter (SERT) through anti-inflammatory factors]. Type of participation: Poster Congress: VII Meeting of Neurosciences. Structure and Function of the Nervous System. Zaragoza (Spain). 6-7 April 2011 Latorre E, Mesonero JE, Matheus N, Mendoza C, Castro M, Grasa L, Plaza MA, Alcalde AI. “Effects of IL-10 on the serotonin transporter (SERT) activity and expression in intestinal epithelial cells”. Type of participation: Oral communication Congress: 3rd Symposium on Veterinary Sciences Münchem-Toulouse-Zaragoza. Münchem (Germany). 3-6 March 2011 Mendoza C, Matheus N, Iceta R, Latorre E, Mesonero JE, Plaza MA, Arruebo P, Murillo D, Castro M, Grasa L, García S, Vicente R, Gros B, Alcalde AI. “Mediators of the intestinal innate immunity inhibit the serotonin transporter activity in intestinal epithelial cells”. Type of participation: Poster Congress: IV Spanish-Portuguese Biophysical Congress. Zaragoza (Spain). 7-10 July 2010 Matheus N, Mendoza C, Iceta R, Latorre E, Mesonero JE, Plaza MA, Arruebo MP, Murillo MD, Castro M, Grasa L, Alcalde AI. “Melatonin effect on serotonin transporter in Caco-2 cells”. Type of participation: Poster Congress: European Intestinal Transport Group (EITG). 23rd Meeting. Salerno (Italy). 7-10 April 2010 Matheus N, Mendoza C, Iceta R. Latorre E, Mesonero JE, Alcalde AI. [Inhibition of serotonin reuptake in inflammatory processes]. Type of participation: Oral communication Congress: VI Meeting of Neurosciences. Structure and Function of the Nervous System. Zaragoza (Spain). 11 December 2009 FELLOWSHIPS Research Fellowships: Organization: Dunhill Medical Trust Subject: Postdoctoral Fellowship. 2015-2018. Organization: Government of Aragon (B105/11) Subject: Doctoral student. 2011-2015. Pharmacology and Physiology Department. Zaragoza University. Organization: Aragon’s Foundation for the study and support inflammatory diseases. Subject: Doctoral student. March-April 2011. Organization: Ministry of Education and Science. Subject: Research student (Collaboration). 2008-2009. Physiology Unit .Zaragoza University Study Scholarships: Organization: Ministry of Education and Science. Subject: Master Degree Studies. 2009-2010. Veterinary Sciences Faculty. Zaragoza University.
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Curriculum Vitae
Eva LATORRE DUQUE
Organization: Ministry of Education and Science. Subject: Degree Studies. 2004-2009. Veterinary Sciences Faculty. Zaragoza University Attendance Grants at Congress: Organization: Zaragoza University Congress: 22nd United European Gastroenterology week. Vienna (Austria). 18-22 October 2014 Organization: Zaragoza University Congress: 25th Congress of the European Intestinal Transport Group (EITG). Bad Herrenalb (Germany), 11-14 Abril 2013. Organization: Spanish Society of Physiological Sciences Congress: Joint FEPS (Federation of European Physiological Societies) and Spanish Physiological Society (SECF) Scientific Congress. Santiago de Compostela, Spain. 2012 Organization: University of Zaragoza Congress: Joint FEPS (Federation of European Physiological Societies) and Spanish Physiological Society (SECF) Scientific Congress. Santiago de Compostela, Spain. 2012 Organization: BIFI (Research Institute Physical Biocomputational and Complex Systems) Congress: V International BIFI Conference. Zaragoza, Spain. 2012 Organization: University of Zaragoza Congress: XXXIV Congress of the Spanish Society of Biochemistry and Molecular Biology. Barcelona, Spain. 2011. Organization: Zaragoza University and München University Congress: 3rd Symposim on Veterinary Sciences. München, Germany. 2011. RESEARCH STAYS for University Academics and Scientists “Study of enteric neuromuscular dysfunctions resulting from abnormal interactions between commensal microbiota and innate immunity” Padova University (Italy). Dr. Giron Laboratory Duration: 5 months Start Date: 01/03/2014 End date: 01/08/2014 ATTENDANCE to SEMINARS, COURSES and SCIENTIFIC EVENTS
Course: Occupational Risk Prevention- Biological hazards (4 hours) Place and year: Zaragoza, Spain. 2015. Entity / group organizer: Zaragoza University
Course: Innovation & Entrepreneurship Place and year: Zaragoza, Spain. 2015. Entity / group organizer: RefBio and Institute Health Research Aragon
Course: Ethical Issues in Research Projects with People (1.2 CME credits) Place and year: Zaragoza, Spain. 2015. Entity / group organizer: Ethics Committee for Clinical Research of Aragon (CEICA)
II Meeting of Spanish Group of Immunotherapy (GEIT) Place and year: Zaragoza, Spain. 2015. Entity / group organizer: Spanish Society of Immunology (SEI)
Basic Science Course “Hot topics in experimental GI cancer” (15 CME credits) Place and year: München, Germany. 2014. Entity / group organizer: UEG
Training Course “Staff responsible for directing and designing animal procedures” Category C. Place and year: Zaragoza, Spain. 2013. Entity / group organizer: Zaragoza University BAEX Code: 001/2013
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Curriculum Vitae
Basic Course of Flow cytometric analysis. Place and year: Zaragoza, Spain. 2013. Entity / group organizer: Health Research Institute of Aragon
Course: Cells in focus: new ways in cell microscopy Place and year: Zaragoza, Spain. 2013. Entity / group organizer: Inycom
Eva LATORRE DUQUE
Course: Mass Spectrometry "New instrumental in UFMS". Place and year: Zaragoza, Spain. 2012. Entity / group organizer: IZASA Course: “Good pipetting practices” Place and year: Zaragoza, Spain. 2012. Entity / group organizer: METTLER TOLEDO Course: "Strategies to increase the quality and impact of scientific publications" Place and year: Zaragoza, Spain. 2012. Entity / group organizer: ELSEVIER First Forum of Innovation in Biomedicine. Place and year: Zaragoza, Spain. 2011. Entity / group organizer: Aragones Institute of Health Sciences Basic Training Course “Web of Knowledge”. Place and year: Zaragoza, Spain. 2011. Entity / group organizer: Thomson Reuters First Conference Immersion Research. Place and year: Zaragoza, Spain. 2007. Entity / group organizer: University of Zaragoza. TEACHER TRAINING Teaching Experience: Participation in the practical teaching of the subject of Physiology in the degree of Veterinary for 3 academic courses (2012-2013, 2013-2014 and 2014-2015), with 60 hours per course. Co-management Bachelor Thesis “Analysis of intestinal epithelial factors that collaborate to the microbiota-host interaction: application to situations of intestinal inflammation” of Alberto Pradilla student of Biotechnology, Faculty of Science (University of Zaragoza) Course 2014-2015. Supervision of Bachelor Thesis “IL-10 effect on serotonin transporter (SERT) of Leanne Hirst, Erasmus student from the University of Reading (UK) September to December 2010. Teaching Publications: Plaza MA, Alcalde AI, Arruebo MP, Gimeno A, Grasa L, Latorre E, Mesonero JE, JM Muñoz, MD Murillo, Rodriguez MJ, Castro M. [Strategies with anti-plagiarism software tools to enhance the originality of the work done by students]. In "Good practices in university teaching with ICT support. Experiences in 2013" Alejandre JL. Chapter 28, pp: 271-280. Editorial Presses University of Zaragoza, Zaragoza, Spain. 2014. ISBN: 978-84-1602897-9. Teaching Conferences: V Conference of Good Practices in University Teaching with ICT support. University of Zaragoza. Spain. 2014. 6th Conference on Educational Innovation and Educational Research University of Zaragoza, Spain 11-12 September 2013. [Strategies for increasing the originality of the work submitted by students using anti-plagiarism software tools. Courses 2010-11 to 2012-13] Authors: MA Plaza, AI Alcalde, MP Arruebo, A Gimeno, L Grasa, E Latorre, JE Mesonero, JM Muñoz, MD Murillo, MJ Rodriguez, M Castro.
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Curriculum Vitae
Eva LATORRE DUQUE
Kind of participation: Poster. Published Online: "Proceedings of the Seventh Conference on Educational Innovation and Educational Research. Zaragoza, 11 and 12 September 2013 ", pp: 33-34. Published by: University of Zaragoza. Vice President for Academic Policy, Institute of Education Sciences. 2013. ISBN: 978-84-695-8538-2. Consultation: http://zaguan.unizar.es/record/12427/files/BOOK--2013-005.pdf. IV Day of Best Practices in University Teaching with ICT support. University of Zaragoza-Banco Santander, Spain 10 September 2013. [Increased degree of originality of the work done by students applying strategies using anti-plagiarism software tools. Study from 2010-11 to 2012-13]. Authors: MA Plaza, AI Alcalde AI, MP Arruebo, A Gimeno, L Grasa, E Latorre, JE Mesonero, JM Muñoz, MD Murillo, MJ Rodriguez, M Castro. Participation: Oral communication Days Virtual collaboration and training USATIC (Ubiquitous and Social: Learning with ICT) Interdisciplinary Educational Research Network on Environments uLearning in Higher Education (Red EuLES). 24-28 June 2013. Zaragoza, Spain. [Effect of anti-plagiarism tools on the degree of originality of the works presented by the students during the courses 2010-11 to 2012-13] Authors: M A Plaza, AI Alcalde, MP Arruebo, A Gimeno, L Grasa, E Latorre, JE Mesonero, JM Muñoz, MD Murillo, MJ Rodríguez, M Castro. Type of participation: Poster. Posted OnLine: "Proceedings of the Virtual Conference Virtual Training Partnership and USATIC 2013, Ubiquitous and Social: Learning with ICT" Allueva AI and Alejandre JL, pp: 263-265. Publisher: Bubok Publishing S.L., Madrid, Spain. 2013. ISBN: 978-84-686-4344-1. Consultation: http://tinyurl.com/ActasVirtualUSATIC-Bubok 2nd Conference on Best Practices in university teaching with ICT support. University of Zaragoza-Banco Santander, Zaragoza, Spain 2011. 5th Conference on Innovation and Educational Research.. University of Zaragoza, Zaragoza, Spain 2011. Courses: Techniques to enhance communication and participation of students in the classroom. 9 hours. Institute of Education Sciences. Zaragoza, Spain. 2015. Learning to teach and teaching to learn. The role of motivation. 12 hours. Institute of Education Sciences. Zaragoza, Spain. 2015. Everybody different, everybody unique. Diversity and teaching: challenges and resources in the classroom. 9 hours. Institute of Education Sciences. Zaragoza, Spain. 2014. Peer learning: methods and techniques of cooperative learning. 6 hours. Institute of Education Sciences. Zaragoza, Spain. 2014. Teacher Training Course for new teachers. 21 hours. Institute of Education Sciences. Zaragoza, Spain. 2013-2014. Innovation as an indicator of higher education quality. 2 hours. Institute of Education Sciences. Zaragoza, Spain. 2013. Innovation in teaching: how to improve the theoretical sessions. 4 hours. Institute of Education Sciences. Zaragoza, Spain. 2013. Competences of university teachers and emotional intelligence. 9 hours. Institute of Education Sciences. Zaragoza, Spain. 2013. Conference: Social-learning: the connected networks as learning ecosystem held from University of Zaragoza-Banco Santander. Zaragoza, Spain 2012 Conference: Social-learning, mobile-learning and audiovisual communication network. held from University of Zaragoza-Banco Santander. Zaragoza, Spain 2012 Concept Maps: teaching usefulness and accomplishment with CmapTools.
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Curriculum Vitae
Eva LATORRE DUQUE
4 hours. Institute of Education Sciences. Zaragoza, Spain. 2012. Using WordPress in educational settings. 3 hours. Institute of Education Sciences. Zaragoza, Spain. 2012. Interdisciplinary networks to study the PBL methodology at the University of Zaragoza. 4 hours. Institute of Education Sciences. Zaragoza, Spain. 2011. OTHERS Training of staff responsible for directing and designing procedures on animals category C. University of Zaragoza. BOA No. 15 (24/01/11). March-April 2013. BAEX Code - 001/2013 Approval of the category B "Training of staff carrying out procedures in experimental animals." BOA nº241 (10/12/14) English B2 Certificate from University of Zaragoza (2014). Member of the Spanish Society of Biochemical and Molecular Biology (SEBBM) since 2015. Member of the Spanish Society of Physiological Sciences (SECF) since 2012. Italian Course 60 hours at University of Padova, Italy 2014. English Course 45 hours in Language Center Limerick, Ireland 2008 (3 week stay) English Course 45 hours in LAL Malta, Malta 2007 (3 week stay)
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