Rossitza Lazova, M.D.

CURRICULUM VITAE Date of Revision:

9/25/2014

Name:

Rossitza Lazova, M.D.

Title:

Associate Professor of Dermatology and Pathology

School Assignment:

Yale University School of Medicine

Education: M.D.

Medical University, Sofia, Bulgaria, 1985 Summa cum laude

Career/Academic Appointments: 1985-88 Resident, Clinical Pathology, Stara Zagora General Hospital, Stara Zagora, Bulgaria 1989-90 Assistant Professor, Clinical Laboratories, National Center for Cardiovascular Diseases, Sofia, Bulgaria 1992-95 Resident, Anatomic and Clinical Pathology, University of Rochester Medical Center, Rochester, NY 1995-96 Chief Resident, Anatomic and Clinical Pathology, University of Rochester Medical Center, Rochester, NY 1996-97 Fellow in Dermatopathology, Institute for Dermatopathology, Jefferson Medical College, Philadelphia, PE 1997-2003 Assistant Professor, Dept. of Dermatology, Yale University School of Medicine, New Haven, CT 1997-present Attending Physician, Yale-New Haven Hospital, New Haven, CT 1998-present Consulting Pathologist/Dermatopathologist, West Haven Veterans Administration Medical Center, West Haven, CT 2003-present Associate Professor, Dept. of Dermatology, Yale University School of Medicine, New Haven, CT Administrative Positions: 2002-present 1989-90

Director, Dermatopathology Fellowship Program, Yale University School of Medicine, New Haven, CT Assistant Director, Clinical Laboratories, National Center for Cardiovascular Diseases, Sofia, Bulgaria

Board Certification: Bulgarian Board of Clinical Pathology, Clinical Pathology, Bulgaria, 1989 Educational Commission for Foreign Medical Graduates, FMGE part I and II, 1992 Federation of State Medical Boards, National Board of Medical Examiners, Federal Licensing Examination, 1992 American Board of Pathology, Anatomic and Clinical Pathology, 1996

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Rossitza Lazova, M.D.

American Boards of Dermatology and Pathology, Dermatopathology, 1997 Professional Honors and Recognition: International/National/Regional 2000: Physician’s Recognition Award in Continuing Medical Education, AMA Awards received during medical school: 1984: Academic Excellence Scholarship Award 1983: Academic Excellence Scholarship Award 1982: Academic Excellence Scholarship Award 1981: Academic Excellence Scholarship Award 1980: Academic Excellence Scholarship Award 1979: Academic Excellence Scholarship Award (Scholarships awarded yearly based on outstanding academic performance in medical school) Grant/Clinical Trials History: Current Grants Agency: NIH/NCRR 8 I.D.# P41GM103391 Title: “Imaging Mass Spectrometry Research Resource at Vanderbilt University” P.I.: Richard Caprioli, Ph.D. Role: Collaborator Direct costs per year: $1,723,202 per year Project period: 2/01/2011-12/31/2015 Total costs for project period: $8,616,010 The “skin project” is one of 7 projects part of this grant. It is the second largest project and is the only multi-institutional and international project. Agency: Access Business Group International LLC Title: “SRA for Access Business Group International” P.I.: John Mason Pawelek, Ph.D. Role: Co-P.I. Direct costs per year: $35,000 Total costs for project period: $105,000 Project period: 01/01/2014 – 12/31/2017 Agency: NIH/NCI I.D.# P50 CA121974 Title: Yale SPORE in Skin Cancer P.I.: Ruth Halaban, Ph.D. Role: Collaborator Project period: 07/01/2012- 06/30/2017

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Rossitza Lazova, M.D.

Past Grants Agency: Gilead Corporation I.D.# YG-005-11 Title: “Genomic Studies of Spitz nevi and Spitzoid malignant melanomas” P.I.: Rossitza Lazova, M.D. Direct costs per year: $93,210 Total costs for project period: $154,729 Project period: 05/01/2012 - 04/30/2014 Agency: Access Business Group International LLC I.D.# 10-001059 Title: “Skin lightening through the use of glycosylation” P.I.: John Mason Pawelek, Ph.D. Role: Co-P.I. Direct costs per year: $35,000 Total costs for project period: $105,000 Project period: 10/01/2010 – 06/30/2014 Agency: DOD I.D.# PR093356 Title: “Studying the role for CD4+ T cell subsets in human lupus” P.I: Insoo Kang, M.D. Role: Collaborator Direct costs per year: $250,000 Total costs for project period: $750,000 Project period: 07/01/10 - 07/31/13 Agency: NIH/NCI I.D.# P50 CA121974 Title: “Yale SPORE in Skin Cancer” P.I.: Ruth Halaban, Ph.D. Total costs for project period: $1, 349,424 Project period: 7/01/06-6/30/12 Developmental Research Project: Title: “Mass Spectrometry analysis of Spitz nevi and Spitzoid Melanomas” P.I.: Rossitza Lazova, M.D. Total costs for project period: $17,000 Project period: 07/01/09 – 06/30/10 Agency: NIH/NCI I.D.# P50 CA121974 Title: “Yale SPORE in Skin Cancer” P.I.: Ruth Halaban, Ph.D. Developmental Research Project: Title: “Determination of the frequency of MIF gene polymorphism and cutaneous expression of MIF in patients with SLE” 3

Rossitza Lazova, M.D.

P.I.: Insoo Kang, M.D. Role: Collaborator Total costs for project period: $50,000 Project period: 07/01/2003 - 6/30/2004

Translational Research: Yale Spitzoid Neoplasm Repository Tissue Acquisition and Processing Core Role: Principal Investigator and Founder http://medicine.yale.edu/dermatology/spitzoid/ Approximately 3,000 specimens Established in 2008 International Spitzoid Neoplasm Study Group Role: Founder Established in 2009 Invited Speaking Engagements, Presentations, Symposia & Workshops Not Affiliated With Yale: International/National International Society of Dermatopathology 2014: XXXVth Symposium of the ISDP, Jerusalem, Israel, Course Director, “Free Communications” session; (Meeting canceled due to the Gaza conflict) 2014: XXXVth Symposium of the ISDP, Jerusalem, Israel, Speaker, Overview and an update on Spitz nevus for Dermatopathologists, Dermatologists and Pathologists; (Meeting canceled due to the Gaza conflict) 2014: 17th Joint Meeting of the ISDP, Denver, CO, Course Director, Dermatopathology Trainee World Cup 2014: 17th Joint Meeting of the ISDP, Denver, CO, Course Director, Oral abstract presentations 2014: 17th Joint Meeting of the ISDP, Denver, CO, Course Director and Speaker, Session “Saved by the patient” 2013: XXXIVth Symposium of the ISDP, Florence, Italy, Course Director, New molecular tests for melanoma diagnosis and therapy 2013: XXXIVth Symposium of the ISDP, Florence, Italy, Videomicroscopy tutorial: Spitzoid melanocytic lesions 2013: 16th Joint Meeting of the ISDP, Miami, FL, Course Director, Dermatopathology Trainee World Cup 2013: 16th Joint Meeting of the ISDP, Miami, FL, Course Director, Oral abstract presentations 2012: XXXIIIrd Symposium of the ISDP, Santa Cruz, Bolivia, Session on New Frontiers in Dermatopathology: “Can mass spectrometry help solve the Spitzoid problem?” 2012: XXXIIIrd Symposium of the ISDP, Santa Cruz, Bolivia, Course Director, Oral platform presentations

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Rossitza Lazova, M.D.

2012: 15th Joint Meeting of the ISDP, San Diego, CA, Course Director and Speaker, Session on New Diseases/New Concepts: “Mass spectrometry – a new era in the diagnosis of Spitzoid neoplasms” 2012: 15th Joint Meeting of the ISDP, San Diego, CA, Course Director, Dermatopathology Trainee World Cup 2012: 15th Joint Meeting of the ISDP, San Diego, CA, Course Director, Free Communications 2011: XXXIInd Symposium of the ISDP, Geneva, Switzerland, Clinico-pathologic Conference: Puzzling diagnoses: “Mass Spectrometry – a new era in the diagnosis of Spitz nevus and Spitzoid malignant melanoma” 2011: XXXIInd Symposium of the ISDP, Geneva, Switzerland, Self-Assessment Session: “Bazex syndrome” 2011: 14th Joint Meeting of the ISDP, New Orleans, LA, Course Director and Speaker, Session on Free Communications: “A positive start in the use of Mass Spectrometry for differentiating Spitz nevi from Spitzoid melanomas” 2011: 14th Joint Meeting of the ISDP, New Orleans, LA, Session on My most “extreme case”: “An unexpected encounter in the 21st century” 2010: XXXIst Symposium of the ISDP, Barcelona, Spain, Course Director and Speaker, Session on Clinicopathologic correlations II: “Spitz Nevus and Atypical Spitzoid Neoplasm – What’s new after 60 years of struggle” 2010: 13th Joint Meeting of the ISDP, Miami, FL, Course Director and Speaker, Session on Dr. A. Bernard Ackerman: The “lives” of a dermatopathologist” 2009: XXXth Symposium of the ISDP, Santiago, Chile, Course Director and Speaker, Session on Unusual Dermatoses: “Unusual folliculitis” 2009: XXXth Symposium of the ISDP, Santiago, Chile, Session on Bernie’s legacy: “Sebaceoma” 2008: XXIXth Symposium of the ISDP, Graz, Austria, Course Director and Speaker, Session on Free communications: “A call for collaboration to solve the Spitzoid neoplasm enigma” 2008: 11th Joint Meeting of the ISDP, San Antonio, TX, Course Director and Speaker, Session on My most extreme case: “Eruptive keratoacanthoma en plaque” 2008: 11th Joint Meeting of the ISDP, San Antonio, TX, Session on Topographical Dermatopathology: “Palms and soles” 2007: XXVIIIth Symposium of the ISDP, Paris, France, Session on Epithelial and Mesenchymal Tumors: “Promontory sign – present in patch and plaque stage of angiosarcoma” 2007: 10th Joint Meeting of the ISDP, Washington, DC, Session on “Seeing is Believing: Saved by the Patient” 2006: XXVIIth Symposium of the ISDP, Malaga, Spain, Interactive Dermatopathologic Session 2006: 9th Joint Meeting of the ISDP, San Francisco, CA, Self-Assessment Course 2005: XXVIth Symposium of the ISDP, Brasilia, Brazil, Session on Neoplastic Diseases: “The gray in melanocytic neoplasms” 1998: 1st Joint Meeting of the ISDP, Orlando, FL, Session on My most unforgettable case – and why: “Acrodermatitis enteropathica - like rash in cystic fibrosis” American Society of Dermatopathology 2013: 50th Annual Meeting of the ASDP, Washington, DC, Hermann Pinkus Basic Science Course: “Mass Spectroscopy as a Diagnostic Tool in Melanocytic Neoplasms” 2012: 49th Annual Meeting of the ASDP, Chicago, IL, Course Director, Oral Abstract Session #1 5

Rossitza Lazova, M.D.

2012: 49th Annual Meeting of the ASDP, Chicago, IL, Short Course IV – Pediatric Dermatopathology: A World of Its Own: “Skin Disease in Children: Reflections of Hematological Disorders” 2008: 45th Annual Meeting of the ASDP, San Francisco, CA, Self-Assessment Course 2002: 39th Annual Meeting of the ASDP, Phoenix, AZ, Self-Assessment Course 2001: 38th Annual Meeting of the ASDP, Chicago, IL, Self-Assessment Course (Meeting canceled due to September 11th tragedy) 1999: 36th Annual Meeting of the ASDP, La Jolla, CA, Self-Assessment Course American Academy of Dermatology 2015: 73rd Annual Meeting of the AAD, San Francisco, CA, Essential Dermatopathology: what you need to know for certification and clinical practice: neoplastic Dermatopathology course: “Benign melanocytic neoplasms” 2015: 73rd Annual Meeting of the AAD, San Francisco, CA, Advanced Dermatopathology: “Atypical Spitzoid Neoplasms – what we do and don’t know” 2014: 72nd Annual Meeting of the AAD, Denver, CO, Dermatopathology for the Pediatric Dermatologist session: “Spitzoid Tumors in Childhood” 2014: 72nd Annual Meeting of the AAD, Denver, CO, Dermatopathology for the Pediatric Dermatologist session: “Great Cases in Pediatric Patients” 2014: 72nd Annual Meeting of the AAD, Denver, CO, Basic Dermatopathology Course: “Benign melanocytic neoplasms” 2013: 71st Annual Meeting of the AAD, Miami, FL, Basic Dermatopathology Course: “Sebaceous neoplasms” 2012: 70th Annual Meeting of the AAD, San Diego, CA, Session ‘Basic Dermatopathology’: “Sebaceous neoplasms” 2011: 69th Annual Meeting of the AAD, New Orleans, LA, Basic Dermatopathology Course: “Sebaceous neoplasms” 2010: 68th Annual Meeting of the AAD, Miami, FL, Basic Dermatopathology Course: “Sebaceous neoplasms” 2010: 68th Annual Meeting of the AAD, Miami, FL, Session on Comprehensive SelfAssessment in Dermatopathology 2009: 67th Annual Meeting of the AAD, San Francisco, CA, Basic Dermatopathology Course: “Sebaceous neoplasms” 2009: 67th Annual Meeting of the AAD, San Francisco, CA, Advanced Dermatopathology Symposium: “Eruptive Keratoacanthoma en Plaque” 2008: 66th Annual Meeting of the AAD, San Antonio, TX, Basic Dermatopathology Course: “Sebaceous neoplasms” 2007: 65th Annual Meeting of the AAD, Washington, DC, Basic Dermatopathology Course: “Sebaceous neoplasms” 2006: 64th Annual Meeting of the AAD, San Francisco, CA, Basic Dermatopathology Course: “Sebaceous neoplasms” 2005: 63rd Annual Meeting of the AAD, New Orleans, LA, Basic Dermatopathology Course: “Sebaceous neoplasms” 2004: 62nd Annual Meeting of the AAD, Washington, DC, Basic Dermatopathology Course: “Sebaceous neoplasms”

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Rossitza Lazova, M.D.

2003: 61st Annual Meeting of the AAD, San Francisco, CA, Basic Dermatopathology Course: “Sebaceous neoplasms” World Congress of Dermatology 2015: 23rd World Congress of Dermatology, Vancouver, Canada, Course Director, ISDP/ASDP companion meeting 2011: 22nd World Congress of Dermatology, Seoul, Korea, Course Director and Speaker, Session on Ackerman's Pattern Analysis: What Is the Impact?: “Ackerman’s Pattern Analysis in the diagnosis of Spitzoid Neoplasms” 2011: 22nd World Congress of Dermatology, Seoul, Korea, Session on Neoplastic Skin Diseases: “The latest on Atypical Spitzoid Neoplasms” 2007: 21st World Congress of Dermatology, Buenos Aires, Argentina, Session on Dermatopathology I - Microscopic patterns of inflammatory skin diseases: “Spongiotic dermatitis” European Academy of Dermatology and Venereology 2013: 22nd Congress of the European Academy of Dermatology and Venereology, Istanbul, Turkey, Session on ‘Novel diagnostic techniques for dermatopathology’: “Application of mass spectrometry to the diagnosis of melanocytic lesions” 2008: 5th Spring Symposium, Istanbul, Turkey, Session on Free Communications: “A distinct entity in the spectrum of the CD30+ cutaneous lymphoproliferative diseases: oligolesional nodules with pseudoepitheliomatous hyperplasia followed by spontaneous resolution” 2005: 3rd Spring Symposium, Sofia, Bulgaria, “Spitz’s nevus versus malignant melanoma” Other 2014: XXth Iberolatinoamerican Congress of Dermatology, Dermatopathology Session, Rio de Janeiro, Brazil 2014: World Congress on Cancers of the Skin; Affiliated Histology Symposium; Co-Director of the Course and Speaker, ‘Melanoma or not? Do the path’ session: “Mass spectrometry in the diagnosis of melanocytic lesions”, Edinburgh, Scotland 2014: XXXth Congress of the International Academy of Pathology, ‘Update in Dermatopathology’ session, “Benign and malignant pigmented lesions”, Bangkok, Thailand 2014: XXXth Congress of the International Academy of Pathology, ‘Interesting cases in Dermatopathology’ session, Bangkok, Thailand 2014: XXXth Congress of the International Academy of Pathology, ‘Inflammatory skin diseases’ session, “Spongiotic dermatitis”, Bangkok, Thailand 2014: 3rd London Dermatopathology Symposium, Speaker, “Differentiating Spitz nevus from Spitzoid melanoma; are we any better?”, London, United Kingdom 2014: 3rd London Dermatopathology Symposium, Multiheader Session: “Challenging melanocytic lesions”, London, United Kingdom 2013: XIth International Congress of Dermatology, Course Director and Speaker, Session on Leishmaniasis, New Delhi, India

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Rossitza Lazova, M.D.

2013: Annual Meeting of the United States and Canadian Academy of Pathology, Baltimore, MD, Session on Pediatric Dermatopathology: “Melanocytic lesions in children: application of Mass Spectrometry to the diagnosis” 2013: Annual Meeting of the United States and Canadian Academy of Pathology, Baltimore, MD, Session on Pediatric Dermatopathology: “Interactive case presentations with application of the principles of Mass Spectrometry in arriving at the correct diagnosis” 2011: 7th Conference in Skin Cancer, Osaka, Japan, “Great cases from Yale University” (Canceled due to the earthquake in Japan) 2003: Young Leaders in Dermatology Symposium, “Dermatopathology – having fun at the boards!”, Tucson, AZ 2000: Sofia Dermatological Society Meeting, Medical Academy, “A potpourri of uncommon skin diseases”, Sofia, Bulgaria Universities 2014: Emory University School of Medicine and Children’s Healthcare of Atlanta. Visiting Professor, October 22, 2014 2014: University of Chicago, Chicago, IL, Department of Medicine, Section of Dermatology. Visiting Professor, Seventh annual Dermatopathology Day, April 16, 2014 2010: Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN: “Mass Spectrometry and Spitzoid Neoplasms” 2010: St. John’s Institute of Dermatology, St. Thomas’ Hospital, London, United Kingdom, St. John’s course on Advanced Dermatopathology: “Spitzoid lesions – Clinicopathologic correlations” 2010: Akdeniz University School of Medicine, Department of Dermatology, Antalya, Turkey: “Spitzoid Melanocytic Neoplasms” 2009: University of Miami, Miller School of Medicine, Miami, FL, Department of Dermatology and Cutaneous Surgery Lecture Series: “The Spitzoid Neoplasm Mystery” 2009: University of Texas, MD Anderson Cancer Center, Houston, TX, Department of Pathology Grand Rounds: “The Spitzoid neoplasm mystery - can we solve it?“ 2005: National Cancer Institute, Pathology Division, Rio de Janeiro, Brazil, “Spitz nevus versus malignant melanoma” 2005: Universidade Federal Fluminense, Department of Pathology Grand Rounds, Niteroi, Brazil, “Dermatology and Dermatopathology go hand in hand” 1996: University of Rochester Medical Center, Rochester, NY, Department of Pathology and Laboratory Medicine Grand Rounds: “Comparative study of LN-2 and CD-34 staining characteristics in spindle cell tumors of the skin” 1995: University of Rochester Medical Center, Rochester, NY, Department of Pathology and Laboratory Medicine Grand Rounds: “Detection of lymphoma in bone marrow specimens: a comparison of three techniques” Regional Danbury Hospital Pathology Grand Rounds, Danbury, CT 2010: “Pattern Analysis in Dermatopathology”

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Rossitza Lazova, M.D.

2009: 2009: 2008: 2008: 2007: 2007: 2006: 2005: 2005: 2004: 2004: 2004: 2003: 2003: 2002: 2002: 2001: 2000:

“Melanocytic lesions – lessons from the past” “Inflammatory skin diseases in a nut shell” “Adnexal neoplasms” “Vascular neoplasms – the good, the bad, and the ugly” “Atypical lymphoid proliferations – what the pathology resident should know!” “Fibrohistiocytic tumors - what's old and what's new?” “Melanocytic lesions – the most feared animal” “Benign and malignant vascular neoplasms” “Histopathologic diagnosis of inflammatory skin diseases - the basics!” “Adnexal neoplasms” “Pathologists and melanocytic lesions” “Potpourri of Dermatopathology” “Mastering Dermatopathology” “Dermatopathology one-on-one” “Infectious diseases of the skin” “Skin cancer and its variants” “Cysts in the skin and tumors of the epidermis” “Soft tissue tumors of the skin”

Yale University and Yale Cancer Center, New Haven, CT 2014: Mass spectrometry in the diagnosis of melanocytic lesions, Yale Cancer Center, Cancer Genetics and Genomics Faculty Lunch, New Haven, CT 2014: Mass spectrometry in the diagnosis of melanocytic lesions, Melanoma Tumor Board, Yale Cancer Center, New Haven, CT 2014: Yale Cancer Center “Answers” on WNPR, Dermatopathology and the Yale Spitzoid Neoplasm Repository, Hartford, CT 2013: Molecular diagnosis of melanocytic lesions by mass spectrometry; Pathology Research in Progress Talks, Department of Pathology, Yale University School of Medicine, New Haven, CT 2013: Tumor-associated melanophages and melanoma progression: Friend or foe; Macrophage Café; monthly interdisciplinary meeting, Yale University School of Medicine, New Haven, CT 2013: Progress in Demystifying the Atypical Spitzoid Neoplasms using Mass Spectrometry; Grand Rounds, Department of Dermatology, Yale University School of Medicine, New Haven, CT 2013: Mass Spectrometry – a helpful diagnostic method for atypical Spitzoid neoplasms; Melanoma Tumor Board, Yale Cancer Center, New Haven, CT 2012: A melanoma metastasis with a donor-patient hybrid genome following bone marrow transplantation; Dermatology Seminar Series, Department of Dermatology, Yale University School of Medicine, New Haven, CT 2012: Mass Spectrometry – a new era in the diagnosis of Spitz nevus and Spitzoid malignant melanoma. Yale Cancer Center Grand Rounds; Yale Cancer Center, New Haven, CT 2011: Spitzoid Neoplasms – what is in it for the surgeons! Grand Rounds, Plastic and Reconstructive Surgery; Yale University School of Medicine, New Haven, CT

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Rossitza Lazova, M.D.

2011: First evidence for cell fusion in human cancer: genetic analyses of a malignant melanoma metastasis to the brain. Melanoma Tumor Board, Yale Cancer Center, New Haven, CT 2011: Yale Cancer Center “Answers” on WNPR, Dermatopathology, Hartford, CT 2011: Mass Spectrometry - an ancillary diagnostic tool in Spitzoid neoplasms; Dermatology Seminar Series, Department of Dermatology, Yale University School of Medicine 2010: Autophagy – a common and targetable feature of malignancy. Yale Cancer Center Grand Rounds; Yale Cancer Center, New Haven, CT 2008: The Spitzoid mystery – Can we solve it? Grand Rounds, Department of Dermatology, Yale University, New Haven, CT 2008: Interface dermatitis; Rheumatology Grand Rounds, Department of Internal Medicine, Yale University, New Haven, CT 2008: A call for collaboration to solve the Spitzoid neoplasm enigma! Melanoma Tumor Board, Yale Cancer Center, New Haven, CT 2004: Cutaneous manifestations of connective tissue diseases; Grand Rounds, Department of Internal Medicine, Section of Rheumatology, Yale University, New Haven, CT 2002: The unique histopathologic features of nevi on and around the ear; Annual Retreat, Department of Pathology, Yale University, Hancock, MA, 2002. 2000: Immunohistochemical analysis for cytokeratin 20 in desmoplastic trichilemmoma and basal cell carcinoma; Annual Retreat, Department of Pathology, Yale University, Southbury, CT 1999: Atypical fibroxanthoma vs. malignant fibrous histiocytoma; Annual Retreat, Department of Pathology, Yale University, Southbury, CT 1999: Dermatopathology Jeopardy; Grand Rounds, Department of Dermatology, Yale University, New Haven, CT Peer-Reviewed Presentations & Symposia Given at Meetings Not Affiliated With Yale: International Society of Dermatopathology 2013: Lazova R, EH, Wititsuwannakul J, Kutzner H, Scolyer R, Cerroni L, Fraitag S, Rodríguez-Peralto JL, Scott G, VollenweiderRoten S, Caprioli RM, Sepehr A. Mass Spectrometry – a helpful diagnostic method for Atypical Spitzoid neoplasms. Oral presentation, 16th Joint Meeting of the ISDP, Miami, FL, American Journal of Dermatopathology 2013, 35(5): e80. 2013: Alomari A, Ariyan S, Narayan D, Klump V, Lazova R. Immunohistochemistry versus Mass Spectrometry in the detection of the differential expression of Vimentin and Actin in Spitz nevi and Spitzoid malignant melanomas. Oral presentation, Dermatopathology Trainee World Cup, 16th Joint Meeting of the ISDP, Miami, FL, American Journal of Dermatopathology 2013, 35(5): e85. 2012: Wong A, Ariyan S, Lazova R. Does a diagnosis of Merkel Cell Carcinoma warrant evaluation of chronic lymphocytic leukemia. Oral presentation, Dermatopathology Trainee World Cup, 15th Joint Meeting of the ISDP, San Diego, CA, American Journal of Dermatopathology 2012, 34(5): e60. 2012: Wititsuwannakul J, Mason AR, Lazova R. Neuropilin-2 (NRP2) as a useful marker in the differential diagnosis of Spitzoid malignant melanoma and Spitz nevus. Oral presentation, Dermatopathology Trainee World Cup, 15th Joint Meeting of the ISDP, San Diego, CA, American Journal of Dermatopathology 2012, 34(5): e62. 10

Rossitza Lazova, M.D.

2012: Mason AR, Wititsuwannakul J, Lazova R. P16 expression does not differentiate between Spitz nevi and Spitzoid malignant melanomas. Oral presentation, Dermatopathology Trainee World Cup, 15th Joint Meeting of the ISDP, San Diego, CA, American Journal of Dermatopathology 2012, 34(5): e62. 2012: Warren CB, Sigal AC, Megan Keenan M, Lazova R. p75 nerve Growth Factor Receptor as a useful marker in the differential diagnosis of dermatofibrosarcoma protuberans and dermatofibroma. Oral presentation, Dermatopathology Trainee World Cup, 15th Joint Meeting of the ISDP, San Diego, CA, American Journal of Dermatopathology 2012, 34(5): e62. 2012: Honarpisheh H, Jedrych J, Samim M, Lazova R, Camp R. Staphylococcal purpura fulminans. Poster presentation, 15th Joint Meeting of the ISDP, San Diego, CA, American Journal of Dermatopathology 2012, 34(5): e71. 2011: Lazova R, Seeley E, Keenan M, Gueorguieva R, Caprioli R. Mass Spectrometry – a promising method to differentiate Spitz nevi from Spitzoid malignant melanoma. Oral presentation, 14th Joint Meeting of the ISDP, New Orleans, LA, American Journal of Dermatopathology 2011, 33(4): 418. 2011: Hung T, Lazova R. Increased mitotic rate and Ki67 expression in ulcerated melanocytic nevi. Oral presentation, 14th Joint Meeting of the ISDP, New Orleans, LA, American Journal of Dermatopathology 2011, 33(4): 422. 2011: Yoo N, Leffell DJ, Aasi SZ, Lazova R. Eruptive Keratoacanthoma en plaque. Oral presentation, 14th Joint Meeting of the ISDP, New Orleans, LA, American Journal of Dermatopathology 2011, 33(4): 421. 2011: Srivastava B, Watsky K, Lazova R. Superficial granulomatous pyoderma ganrenosum presenting as disfiguring ulcers. Oral presentation, 14th Joint Meeting of the ISDP, New Orleans, LA, American Journal of Dermatopathology 2011, 33(4): 424. 2011: Koochek A, Ko CJ, Lazova R. Non-Langerhans cell histiocytoses and malignancy. Poster presentation, 14th Joint Meeting of the ISDP, New Orleans, LA, American Journal of Dermatopathology 2011, 33(4): 427. 2011: Nagarajan P, Notaro W, Lazova R. Steroid-resistant lymphohistiocytic Sweet’s syndrome. Poster presentation, 14th Joint Meeting of the ISDP, New Orleans, LA, American Journal of Dermatopathology 2011, 33(4): 428. 2009: Sigal A, Lazova R. The Power of NGF-R (p75) in the diagnosis of spindle cell and desmoplastic malignant melanoma. Oral presentation, 12th Joint Meeting of the ISDP, San Francisco, CA, American Journal of Dermatopathology 2009, 31(4): 414. 2006: Galan A, Lazova R. GLI2 does not distinguish between basal cell carcinoma and benign adnexal tumors. Oral presentation, 9th Joint Meeting of the ISDP, American Journal of Dermatopathology 2006, 28(3): 230. 2001: Balfour E, Antaya R, Lazova R. Subcutaneous fat necrosis of the newborn presenting as a large plaque with lobulated cystic areas. Oral presentation, 4th Joint Meeting of the ISDP, Washington, DC, American Journal of Dermatopathology 2001, 23:356. 2001: Lazova R, McNiff JM, Handerson T, Gueorguieva R, Glusac EJ. Immunohistochemical analysis of cytokeratin 20 in desmoplastic trichilemmoma and basal cell carcinoma. Oral presentation, 4th Joint Meeting of the ISDP, Washington, DC, American Journal of Dermatopathology 2001, 23:352.

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Rossitza Lazova, M.D.

2001: Lazova R, McNiff JM, Glusac EJ. Acute lipodermatosclerosis – report of two cases. Oral presentation, 4th Joint Meeting of the ISDP, Washington, DC, American Journal of Dermatopathology 2001, 23:354. 2001: Lester B, McNiff JM, Glusac EJ, Handerson T, Lazova R. The unique histopathological features of nevi on and around the ear. Oral presentation, 4th Joint Meeting of the ISDP, Washington, DC, American Journal of Dermatopathology 2001, 23:353. 1998: Lazova R, Scott G. CD-74 (LN-2): A useful marker to distinguish leiomyosarcoma from leiomyoma. Poster presentation, XIXth Symposium of the ISDP, Madrid, Spain, American Journal of Dermatopathology 1998, 20:21. American Society of Dermatopathology 2014: Alomari A, Glusac EJ, Choi JN, Hui P, Seeley EH, Caprioli RM, Lazova R. Congenital nevi versus metastatic melanoma in a newborn to a mother with malignant melanoma – diagnosis supported by sex chromosome analysis and Imaging Mass Spectrometry. Oral presentation; 15th Annual Duel in Dermatopathology Resident Competition, 51st Annual Meeting of the ASDP, Chicago, IL, 2014. 2013: Myung P, Deschene E, Somach S, Lazova R, Rosenberg A, Winfield H, and Greco V. Wnt signaling in hair follicle stem cell progenitors drives human hair follicle growth. Oral presentation, Fellows' Case Presentations, 50th Annual Meeting of the ASDP, Washington, DC, 2013, Journal of Cutaneous Pathology 2014, 41:155. 2013: Srisuttiyakorn C, Reddy S, Reeve J, Imaeda S, Lazova R. Subcutaneous histiocytoid Sweet’s syndrome in a patient with myelodysplastic syndrome and acute myeloblastic leukemia. Poster presentation, 50th Annual Meeting of the ASDP, Washington, DC, 2013, 50th Annual Meeting of the American Society of Dermatopathology, Washington, DC, 2013, Journal of Cutaneous Pathology 2014, 41:187. 2013: Lilly E, Pettersen J, Tomayko M, Lazova R. A possible role for occlusion and/or moisture in papular acantholytic dyskeratosis of the vulva. Poster presentation, 50th Annual Meeting of the American Society of Dermatopathology, Washington, DC, 2013, Journal of Cutaneous Pathology 2014, 41: 270. 2013: Hou Z, Christensen S, Leffell D, Lazova R. Dermatofibroma of the forehead: a benign cutaneous neoplasm with invasive features and high recurrence rate. Poster presentation, 50th Annual Meeting of the ASDP, Washington, DC, 2013, Journal of Cutaneous Pathology 2014, 41: 227. 2013: Honarpisheh H, Lott J, Warren C, Stavert R, Lazova R. Levamisole vasculitis – a case series with histopathologic characteristics. Poster presentation, 50th Annual Meeting of the ASDP, Washington, DC, 2013, Journal of Cutaneous Pathology 2014, 41:187. 2011: Mason AR, Sadeghpour M, Antaya RJ, Lazova R, Ko CJ. Dilated lymphatic vessels in tufted angioma: a potential source of diagnostic confusion. Oral presentation, 48th Annual Meeting of the ASDP, Seattle, WA, Journal of Cutaneous Pathology 2012, 39:100. 2011: Wong A, Prasad M, Ariyan S, Lazova R. Metastatic melanoma resembling a fibrohistiocytic tumor with osteoclast-like giant cells. Poster presentation, 48th Annual Meeting of the ASDP, Seattle, WA, Journal of Cutaneous Pathology 2012, 39:125. 2011: Gallagher P, Jedrych J, Lazova R, Reyes-Mugica M. Blueberry muffin baby due to mevalonate kinase deficiency syndrome: inborn error of metabolism presenting with

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2010:

2010: 2009: 2008: 2008: 2008: 2007: 2007: 2007: 2007: 2006: 2005:

2004: 1999:

cutaneous extramedullary hematopoiesis. Poster presentation, 48th Annual Meeting of the ASDP, Seattle, WA, Journal of Cutaneous Pathology 2012, 39:204. Milless T, Braverman I, High W, Zeiss C, Lazova R, Cowper S. Non-granulomatous cutaneous silica nodules in a kayaker. Oral presentation, Duel in Dermatopathology, 47th Annual Meeting of the ASDP, Atlanta, GA, Journal of Cutaneous Pathology 2011, 38:85. Nagarajan P, Craig E, Terner J, Narayan D, Lazova R. Auricular melanoma: a retrospective study of 100 cases. Poster presentation, 47th Annual Meeting of the ASDP, Atlanta, GA, Journal of Cutaneous Pathology 2011, 38:88. Knopp E, Colegio O, Lazova R. Secondary hemophagocytosis in a patient with chronic urticaria. Poster presentation, 46th Annual Meeting of the ASDP, Chicago, IL, Journal of Cutaneous Pathology 2010, 37:178. Finkelstein A, Lazova R. Cutaneous sclerodermatous graft versus host disease. Poster presentation, 45th Annual Meeting of the ASDP, San Francisco, CA, Journal of Cutaneous Pathology 2009, 36:117. Sigal A, Lazova R. A case of periumbilical perforating pseudoxanthoma elasticum. Poster presentation, 45th Annual Meeting of the ASDP, San Francisco, CA, Journal of Cutaneous Pathology 2009, 36:146. Lazova R. A call for collaboration to solve the Spitzoid neoplasm enigma. An address to the membership, 45th Annual Meeting of the ASDP, San Francisco, CA. Knopp E, Diette KM, Ko C, Lazova R. Common blue nevus with satellitosis. Oral presentation, Duel in Dermatopathology, 44th Annual Meeting of the ASDP, Baltimore, MD, Journal of Cutaneous Pathology 2008, 35:93. Zayour M, Gilmore E, Heald P, Rose M, Lazova R. CD30+ large cell lymphoma with pseudoepitheliomatous hyperplasia. Poster presentation, 44th Annual Meeting of the ASDP, Baltimore, MD, Journal of Cutaneous Pathology 2008, 35:122. Whisenant K, Ma L, Braverman IM, Lazova R. Targetoid nodule on the thumb in a 64year-old woman. Poster presentation, 44th Annual Meeting of the ASDP, Baltimore, MD, Journal of Cutaneous Pathology 2008, 35:102. Galan A, McNiff JM, Choi JN, Lazova R. Fatal HHV6 infection presenting with skin involvement in an immunocompromised patient. Poster presentation, 44th Annual Meeting of the ASDP, Baltimore, MD, Journal of Cutaneous Pathology 2008, 35:149. Hathaway TR, Gueorguieva R, Lazova R. The characteristic histopathologic features of nevi on the lower leg. Poster presentation, 43rd Annual Meeting of the ASDP, Chicago, IL, Journal of Cutaneous Pathology 2007, 34:119. Rashidi HH, Barry CI, Lazova R. Diagnostic role of c-Kit (CD117) in microcystic adnexal carcinoma, syringoma, trichoepithelioma, and basal cell carcinoma. Poster presentation, 42nd Annual Meeting of the ASDP, Seattle, WA, Journal of Cutaneous Pathology 2006, 33:108-109. Bhattacharjee P, Lazova R. Immunohistochemical expression of cutaneous leiomyosarcoma. Poster presentation, 41st Annual Meeting of the ASDP, Boston, MA, Journal of Cutaneous Pathology 2005, 32:76. Balfour E, Zalka A, Lazova R. Creeping eruption in a 39-year-old Caucasian man. Oral presentation, 36th Annual Meeting of the ASDP, La Jolla, CA. Journal of Cutaneous Pathology 1999, 26:415.

13

Rossitza Lazova, M.D.

1996: Lazova R, Moynes R, May D, Scott G. CD-74: A useful marker to distinguish atypical fibroxanthoma from malignant fibrous histiocytoma. Oral presentation, 33rd Annual Meeting of the ASDP, Washington, DC, Journal of Cutaneous Pathology 1996, 23:54. 1995: Lazova R, Slater C, Scott G. Reactive angioendotheliomatosis: Report of a case in a 50year-old man. Oral presentation, 32nd Annual Meeting of the ASDP, New Orleans, LA, Journal of Cutaneous Pathology 1995, 22:70. American Academy of Dermatology 2014: Lilly E, Lazova R, Landry ML, Golden M, Tomayko M. Genital ulceration in a patient with well-controlled HIV. Oral presentation, 71st Annual Meeting of the AAD, Denver, CO. 2012: Bunick CG, Srivastava B, Lazova R, Ko CJ, Watsky K. Superficial granulomatous pyoderma of the head, neck, and chest. Oral presentation, 70th Annual Meeting of the AAD, San Diego, CA. 2007: Choi JN, Heald P, Lazova R. A 56-year-old woman with clavus-like depressions on palms and soles. Oral presentation, 65th Annual Meeting of the AAD, Washington, DC. 2006: Poligone B, Lazova R, Kucher C, Heald P. Primary cutaneous nodular amyloidosis. Oral presentation, 64th Annual Meeting of the AAD, San Francisco, CA. 2006: Gilmore ES, Lazova R, Heald P. Treatment of a 79-year-old patient with steroid-resistant pemphigus vulgaris. Oral presentation, 64th Annual Meeting of the AAD, San Francisco, CA. 2006: Fuller B, Lazova R, Heald P. Management of acrodermatitis continua of Hallopeau in a 68-year-old man with a history of lymphoma. Oral presentation, 64th Annual Meeting of the AAD, San Francisco, CA. 2005: Gohara M, Feng J, Antaya R, Lazova R. A rare case of calciphylaxis in a 10-year-old boy with end stage renal disease. Oral presentation, 63rd Annual Meeting of the AAD, New Orleans, LA. 2004: Mak M, Imaeda S, Lazova R. Peripheral T-cell lymphoma presenting with paraneoplastic pemphigus, celiac sprue, monoclonal light chain kidney disease and features of antiphospholipid syndrome. Oral presentation, 62nd Annual Meeting of the AAD, Washington, DC. 2004: Giovanielli K, Lazova R, Heald P. A case of reactive angioendotheliomatosis in a 71year-old patient. Oral presentation, 62nd Annual Meeting of the AAD, Washington, DC. 2004: Taraszka K, Chavel S, Schaffer J, Lazova R, Schechner J. Calciphylaxis associated with acute, reversible renal failure in the setting of alcoholic cirrhosis. Oral presentation, 62nd Annual Meeting of the AAD, Washington, DC. 2004: Moss J, Lazova R. Calcinosis cutis: a complication of intravenous administration of calcium gluconate. Oral presentation, 62nd Annual Meeting of the AAD, Washington, DC. 2003: Taraszka K, Lazova R, Bolognia JL. Combination of suppurative folliculitis and lymphocytic vasculitis: a clue to the diagnosis of Behçet’s disease. Oral presentation, 61st Annual Meeting of the AAD, San Francisco, CA. 2002: Kauls L, Heald P, Lazova R. Scleromyxedema with fever, coma and seizures in a previously healthy 45-year-old-woman. Oral presentation, 60th Annual Meeting of the AAD, New Orleans, LA.

14

Rossitza Lazova, M.D.

2002: Kaplan D, Lazova R, Schechner J. More than oatmeal: Scurvy in a schizophrenic patient. Oral presentation, 60th Annual Meeting of the AAD, New Orleans, LA. 2002: Chen E, Lazova R, Herrick C. Eosinophilic cellulitis (Wells syndrome) in a 29-year-old woman. Oral presentation, 60th Annual Meeting of the AAD, New Orleans, LA. 2000: Fisher N, Marsh E, Lazova R. Extensive localized argyria following the application of silver sulfadiazine cream to a post-surgical wound. Oral presentation, 58th Annual Meeting of the AAD, San Francisco, CA. 1999: Radonich M, Lazova R, Bolognia JL. Aggressive natural killer cell leukemia/lymphoma presenting as widespread cutaneous lesions. Oral presentation, 57th Annual Meeting of the AAD, New Orleans, LA. American Association for Cancer Research 2011: Lazova R, LaBerge GS, Duvall E, Spoelstra N, Sznol M, Cooper D, Spritz R, Pawelek JM. Tumor cell-leukocyte fusion in human cancer: a melanoma brain metastasis with a donor-patient hybrid genome following allogeneic bone marrow transplantation. Poster presentation, 102nd Annual Meeting of the AACR, Orlando, FL. 2011: Lazova R, Camp RL, Klump V, Siddiqui SF, Pawelek J. LC3B-positive autophagosomes are a common feature of solid tumors and associated with proliferation, metastasis and poor outcome. Poster presentation, 102nd Annual Meeting of the AACR, Orlando, FL. 2006: Pawelek J, Yilmaz Y, Handerson T, Lazova R, Chakraborty A, Cooper D. Bone marrowtumor cell hybrids are a principle source of tumor β 1,6-branched oligosaccharides in two cases of renal cell carcinoma. Poster presentation, 97th Annual Meeting of the AACR, Washington, DC. 2005: Yilmaz Y, Lazova R, Qumsiyeh M, Cooper D, Pawelek J. Donor Y chromosome in renal carcinoma cells of a female BMT recipient. Poster presentation, 96th Annual Meeting of the AACR, Anaheim, CA. 2004: Chakraborty A, Lazova R, Davies S, Backvall H, Ponten F, Brash D, Pawelek J. Genetic evidence for tumor-hematopoietic cell hybrids in a human renal cell carcinoma metastasis. Poster presentation, 95th Annual Meeting of the AACR, Orlando, FL. Other 2013: Lazova R, Seeley EH, Wititsuwannakul J, Kutzner H, Scolyer R, Prieto VG, Cerroni L, Fraitag S, Rodriguez-Peralto JL, Riveiro-Falkenbach E, Scott G, VollenweiderRoten S, Caprioli RM, Ariyan S, Narayan D, Sepehr A. Imaging Mass Spectrometry - a novel ancillary method for the diagnosis of malignant melanoma. Poster presentation, International Investigative Dermatology 2013, Edinburg, Scotland. 2013: Seeley EH, Sepehr A, Caprioli RM. Molecular diagnosis of Atypical Spitzoid Neoplasms using direct tissue profiling Mass Spectrometry. Oral presentation, 61st Conference of the American Society for Mass Spectrometry, June, 9-13, Minneapolis, MN. 2012: Shin MS, Kang Y, Lee N, Kim SH, Kang KS, Lazova R, Kang I. U1-snRNP activates the NLRP3 inflammasome in human monocytes. Immunology 2012; the 99th American Association of Immunologists Annual Meeting, Boston, MA; Journal of Immunology 2012, 188:171.7. 2012: Broer N, Walker M, Mody P, Patel A, Lazova R, Narayan D, Ariyan S. Desmoplastic melanoma - repair of resection site: Skin flaps versus skin grafts. Poster presentation, 32nd Congress of the European Society of Surgical Oncology, Valencia, Spain. 15

Rossitza Lazova, M.D.

2012: Broer PN, Walker ME, Goldberg C, Buonocore S, Braddock DT, Lazova R, Narayan D, Ariyan S. Desmoplastic melanoma: A 12-year experience with sentinel lymph node biopsy. Oral presentation, 32nd Congress of the European Society of Surgical Oncology, Valencia, Spain. 2011: Lazova R, Camp RL, Klump V, Siddiqui SF, Pawelek J. LC3B punctate expression, a marker for autophagosomes, is a common feature of melanomas and breast carcinomas and associated with proliferation, metastasis, high nuclear grade and poor outcome. Oral presentation, XXIst International Pigment Cell Conference, Bordeaux, France. 2011: Lazova R, LaBerge GS, Duvall E, Spoelstra N, Sznol M, Cooper D, Spritz R, Pawelek JM. First evidence for tumor cell-leukocyte fusion in human cancer: a melanoma brain metastasis with a donor-patient hybrid genome following allogeneic bone marrow transplant. Oral presentation, XXIst International Pigment Cell Conference, Bordeaux, France. 2010: McRae MC, Narayan D, Lazova R, David Rimm. Subcellular Localization of NEDD9 and HMB45 with AQUA technology to distinguish Spitz nevi from Spitzoid melanoma. Poster presentation, Annual Meeting of the American Society of Plastic Surgeons, Toronto, Canada. 2009: 10th International Congress of Dermatology, Prague, Czech Republic, Session on Free Communications: “P75 (NGF-R) - superior to S100 in identifying spindle cell and desmoplastic melanoma” 2009: XVth PanAmerican Society for Pigment Cell Research Conference, Memphis, TN: “Autophagy in cutaneous malignant melanoma, malignant transformation of the melanocyte, and melanoma progression” 2008: SPOREs in Skin Cancer Workshop, New Haven, CT, “Spitzoid Biospecimen and Data Repository” 2007: Lazova R, Handerson T, Klump V, Pawelek J. An aberrant Golgi complex correlates with high levels of autophagy and β1,6-branched oligosaccharides in cutaneous malignant melanoma. Oral presentation, 14th Annual PanAmerican Society for Pigment Cell Research (PASPCR) Meeting Pigmentation and Diversity, Chicago, IL. 2007: Lazova R, Handerson T, Klump V, Pawelek J. A new phenotype in malignant melanoma: Vesiculated Golgi complex, beta 1,6-branched N-glycosylation and autophagy. Poster presentation, 4th International Melanoma Conference, New York, NY. 2006: Handerson T, Pawelek J, Klump V, Lazova R. Nest-specific Golgi complex abnormalities in cutaneous malignant melanoma. Poster presentation, Third International Melanoma Research Congress, Amsterdam, Netherlands, Melanoma Research 2006, 16(Suppl 1): S66. 2004: Yilmaz Y, Lazova R, Qumsiyeh M, Cooper D, Pawelek J. Direct visualization of hybrid tumor cells in human cancer by FISH: Donor Y chromosome in renal carcinoma cells of a female BMT recipient. Poster presentation, Annual Meeting of the American Society for Human Genetics, Toronto, Canada. 2004: Yilmaz Y, Lazova R, Qumsiyeh M, Cooper D, Pawelek J. Direct visualization of hybrid tumor cells in human cancer by FISH: Donor Y chromosome in renal carcinoma cells of a female BMT recipient. Poster presentation, Second International Melanoma Research Congress, Phoenix, AZ. 2002: Strasswimmer J, Antaya R, Lazova R, Leffell D. Numerous mucosal granular cell tumors in a child. Oral presentation, 20thWorld Congress of Dermatology, Paris, France. 16

Rossitza Lazova, M.D.

2001: Olhoffer IH, Lazova R, Leffell D. Sources and consequences of histopathologic misdiagnosis. Oral presentation, Combined Annual Meeting, American Society for Dermatologic Surgery and American College of Mohs Micrographic Surgery & Cutaneous Oncology, Dallas, TX. 1994: Lazova R, Sheils L, Hicks D, Ryan D. Detection of lymphoma in bone marrow specimens: A comparison of three techniques. Poster presentation, Annual Meeting of the American Society of Clinical Pathologists, Seattle, WA, American Journal of Clinical Pathology 1994, 101:390. 1994: University of Rochester Medical Center, Rochester, NY, Department of Pathology and Laboratory Medicine Research Day: “Different approaches to detection of lymphoma in bone marrow specimens” Professional Service Journal Service: Associate Editor: 2013-present Associate Editor, Dermatopathology Editorial Board Member: 2014-present Editorial Board Member, Journal of Clinical and Investigative Dermatology 2013-present Editorial Board Member, the American Journal of Contemporary Dermatology 2013-present Editorial Board Member, the American Journal of Dermatology 2012-present Editorial Board Member, F1000 Research 2011-present Editorial Board Member, Clinical & Experimental Dermatology Research 2011-present Editorial Board Member, Journal of Cancer Therapeutics and Research 2011-present Editorial Board Member, Clinical & Experimental Pathology 2009-present Editorial Board Member, Dermatology Research and Practice 2008-present Editorial Board Member, the American Journal of Dermatopathology Reviewer: 2014-present Reviewer for: • Melanoma Research 2013-present Reviewer for: • British Journal of Dermatology • Cancer biomarkers • Indian Journal of Dermatology, Venereology and Leprology • Clinical & Experimental Dermatology • Melanoma Research 2012-present Reviewer for: • Journal of Investigative Dermatology 2011-present Reviewer for: • European Journal of Dermatology • Proteome Science 2006-present Reviewer for: • Faculty of 1000 Medicine

17

Rossitza Lazova, M.D.

2002-present Reviewer for: • Journal of the American Academy of Dermatology • American Journal of Dermatopathology • Archives of Dermatology • Journal of Cutaneous Pathology Professional Service for Professional Organizations American Society of Dermatopathology 2011-present Member, In-service Exam Subcommittee 2007-09 Chair, Mentorship in Dermatopathology Award Committee 2005-2012 Member, Mentorship in Dermatopathology Award Committee 2003-04 Member, Board of Directors 2003-04 Chair, Membership Committee 2002 Representative of the ASDP to the International Committee for Dermatopathology 2002-present Member, Council of Directors of Fellowship Training Programs in Dermatopathology 1999-2003 Member, Membership Committee 1997-present Contributor, Slide Library International Society of Dermatopathology 2013-2016 Vice President, International Society of Dermatopathology 2013-present Member, Scientific Committee for the XXXVth Symposium of the IDSP in Jerusalem, Israel, in September 2014 2011-present Liaison from the ISDP to the International Society of Dermatology and the International League of Dermatological Societies 2008-present Chair, Travel Award Committee 2009-present Member, Organizing Committee for the Joint Meetings of the IDSP 2007-present Member, Executive Committee 2007-2014 Member, Membership Committee American Academy of Dermatology 2009 Panel member, Sharing Mentoring Experiences, 67th Annual Meeting of the American Academy of Dermatology, San Francisco, CA 2008 Panel member, Sharing Mentoring Experiences, 66th Annual Meeting of the American Academy of Dermatology, San Antonio, TX Other 2009-present Member, Yale Comprehensive Cancer Center, Cancer Genetics and Genomics Program 2006-present Member, Skin Cancer Section, Faculty of 1000 Medicine (www.f1000medicine.com) 1995-96

Foreman of New York State Delegation to the College of American Pathologists Resident Forum; Resident Representative to the Executive Council of New York State Society of Pathologists 18

Rossitza Lazova, M.D.

1994-96

New York State Delegate to CAP-Residents Forum, College of American Pathologists

Meeting Planning/Participation 2013-14 Member, Organizing Committee, XXXV Symposium of the International Society of Dermatopathology, Jerusalem, Israel, 2014 2013-14 Member, Organizing Committee, 17th Joint Meeting of the International Society of Dermatopathology, Denver, CO, 2014 2012-13 Member, Organizing Committee, 16th Joint Meeting of the International Society of Dermatopathology, Miami, FL, 2013 2012-13 Member, Organizing Committee, 2nd International Conference and Exhibition on Pathology 2013, Las Vegas, NV, 2013 2011-12 Member, Organizing Committee, 15th Joint Meeting of the International Society of Dermatopathology, San Diego, CA, 2012 2011-12 Member, Organizing Committee, XXXIIIrd Symposium of the International Society of Dermatopathology, Santa Cruz, Bolivia, 2012 2012-13 Member, Organizing Committee, 3rd International Conference on Clinical & Experimental Dermatology 2013, Chicago, IL, 2013 2010-11 Member, Organizing Committee, 14th Joint Meeting of the International Society of Dermatopathology, New Orleans, LA, 2011 2009-10 Member, Organizing Committee, 13th Joint Meeting of the International Society of Dermatopathology, Miami, FL, 2010 Yale University Service: Medical School Committees 2000-04 Member, Admissions Committee, Yale School of Medicine 2000-09 Member, Committee on the Status of Women in Medicine (SWIM), School of Medicine 2000-05 Member, Board of Directors, Phyllis Bodel Childcare Center, School of Medicine Departmental Committees 2002-present Chair, Dermatopathology Fellowship Program Committee, Dept. of Dermatology, School of Medicine 2013-present Member, Clinical Competency Committee, Dept. of Dermatology, Dermatopathology fellowship Public Service: 2011 Guest, Yale Cancer Center “Answers” on WNPR, Yale Cancer Center: “Dermatopathology” 2014 Guest, Yale Cancer Center “Answers” on WNPR, Yale Cancer Center: “What is new in Dermatopathology Research”; broadcasted on March 16, 2014 Bibliography: Peer-Reviewed Original Research 19

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1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11.

12. 13. 14.

15. 16.

Lazova R, Moynes R, May D, Scott G. LN-2 (CD74). A marker to distinguish atypical fibroxanthoma from malignant fibrous histiocytoma. Cancer 1997, 79:2115-2124. McNiff JM, Glusac EJ, Lazova RZ, Carroll CB. Morphea limited to the superficial reticular dermis: an underrecognized histologic phenomenon. American Journal of Dermatopathology 1999, 21:315-319. Lazova R, Shapiro PE. Juvenile xanthogranuloma versus Langerhans cell histiocytosis (histiocytosis X). Seminars in Cutaneous Medicine and Surgery 1999, 18:71-77. Schaffer JV, Orlow SJ, Lazova R, Bolognia JL. Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi. Archives of Dermatology 2001, 137:172-178. Radonich MA, Lazova R, Bolognia J. Cutaneous natural killer/T-cell lymphoma. Journal of the American Academy of Dermatology 2002, 46(3): 451-456. Olhoffer IH, Lazova R, Leffell DJ. Histopathologic misdiagnoses and their clinical consequences. Archives of Dermatology 2002, 138:1381-1383. Lazova R, Lester B, Glusac EJ, Handerson T, McNiff J. The characteristic histopathological features of nevi on and around the ear. Journal of Cutaneous Pathology 2005, 32:40-44. McNiff JM, Cowper SE, Lazova R, Subtil A, Glusac EJ. CD56 staining in Merkel cell carcinoma and natural killer-cell lymphoma: Magic bullet, diagnostic pitfall, or both? Journal of Cutaneous Pathology 2005, 32:541-545. McNiff JM, Subtil A, Cowper SE, Lazova R, Glusac EJ. Cellular digital fibromas: distinctive CD34-positive lesions that may mimic dermatofibrosarcoma protuberans. Journal of Cutaneous Pathology 2005, 32:413-418. Adams BD, Lazova R, Andrews NC, Milstone LM. Iron in skin of mice with three etiologies of systemic iron overload. Journal of Investigative Dermatology 2005, 125:1200-1205. McCarthy MM, DiVito KA, Sznol M, Kovacs D, Halaban R, Berger AJ, Flaherty KT, Camp RL, Lazova R, Rimm D, Kluger HM. Expression of tumor necrosis factor-related apoptosis-inducing ligand receptors 1 and 2 in melanoma. Clinical Cancer Research 2006, 12(12): 3856-3863. Lee CJ, Whang JH, Lazova R, Ciesielski TE, Thomson JG, McCarthy T, Persing JA. Growth factor expression with different wound treatments after laser resurfacing. Aesthetic Surgery Journal 2007, 27(1): 55-64. McCarthy MM, Pick E, Kluger Y, Gould-Rothberg B, Lazova R, Camp RL, Rimm DL, Kluger HM. HSP90 as a marker of progression in melanoma. Annals of Oncology 2008, 19(3): 590-594. Zayour M, Gilmore E, Heald P, Rose M, Poligone B, Lazova R. A distinct entity in the spectrum of the CD30+ cutaneous lymphoproliferative diseases: Oligolesional nodules with pseudoepitheliomatous hyperplasia followed by spontaneous resolution. American Journal of Dermatopathology 2009, 31(1): 37-43. Lazova R, McNiff JM, Glusac EJ, Godic A. Promontory sign - present in patch and plaque stage of angiosarcoma! American Journal of Dermatopathology 2009, 31(2): 132136. Lazova R, Gould-Rothberg B, Rimm D, Scott G. The Semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis. American Journal of Dermatopathology 2009, 31(2): 177-181.

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17. 18. 19. 20.

21. 22. 23. 24. 25. 26. 27. 28. 29. 30.

31. 32.

Lazova R, Pawelek JM. Why do melanomas get so dark? Experimental Dermatology 2009, 18(11): 934-938. Lazova R, Klump V, Pawelek J. Autophagy in cutaneous malignant melanoma. Journal of Cutaneous Pathology 2010, 37:256-268. Lazova R, Tantcheva-Poor I, Sigal AC. P75 nerve growth factor receptor staining superior to S100 in identifying spindle cell and desmoplastic melanoma. Journal of the American Academy of Dermatology 2010, 63(5): 852-858. Godshalk SE, Paranjape T, Nallur S, Speed W, Chan E, Molinaro AM, Bacchiocchi A, Hoyt K, Tworkoski K, Stern DF, Sznol M, Ariyan S, Lazova R, Halaban R, Kidd KK, Weidhaas JB, Slack FJ. A Variant in a MicroRNA complementary site in the 3’UTR of the KIT oncogene increases risk of acral melanoma. Oncogene 2011, 30(13): 1542-1550. Lazova R, Seeley EH, Keenan M, Gueorguieva R, Caprioli RM. Imaging mass spectrometry – a new and promising method to differentiate Spitz nevi from Spitzoid malignant melanomas. American Journal of Dermatopathology 2012, 34(1): 82-90. Sigal AC, Keenan M, Lazova R. P75 nerve growth factor receptor as a useful marker to distinguish spindle cell melanoma from other spindle cell neoplasms of sun-damaged skin. American Journal of Dermatopathology 2012, 34(2): 145-150. Lazova R, Camp RL, Klump V, Siddiqui SF, Amaravadi R, Pawelek JM. Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome. Clinical Cancer Research 2012, 18(2): 370-379. Sadeghpour M, Antaya RJ, Lazova R, Ko CJ. Dilated lymphatic vessels in tufted angioma: A potential source of diagnostic confusion. American Journal of Dermatopathology 2012, 34(4): 400-403. Zayour M, Bolognia JL, Lazova R. Multiple Spitz nevi: A clinicopathologic study of 9 patients. Journal of the American Academy of Dermatology 2012, 67:451-458. Shin MS, Kang Y, Lee N, Kim SH, Kang KS, Lazova R, Kang I. U1-Small nuclear ribonucleoprotein activates the NOD-like receptor family, pyrin domain-containing 3 inflammasome in human monocytes. Journal of Immunology 2012, 188(10): 4769-4775. Mason A, Wititsuwannakul J, Klump V, Lott J, Lazova R. p16 expression does not differentiate between Spitz nevi and Spitzoid malignant melanomas. Journal of Cutaneous Pathology 2012, 39(12): 1062-74. Wititsuwannakul J, Mason A, Klump V, Lazova R. Neuropilin-2 (NRP2) as a useful marker in the differentiation between Spitzoid malignant melanoma and Spitz nevus. Journal of the American Academy of Dermatology, 2013; 68(1): 129-37. Craig ES, Nagarajan P, Lee ES, Lazova R, Terner J, Narayan D. The Perichondrium in Auricular Melanomas: Implications for Surgical Management. Otolaryngology Head and Neck Surgery, 2013; 148(3): 431-5. Shin MS, Kang Y, Lee N, Kim SH, Kang KS, Lazova R, Kang I. Self double-stranded (ds) DNA induces IL-1β production from human monocytes by activating NLRP3 inflammasome in the presence of anti-dsDNA antibodies. Journal of Immunology. 2013, 190(4): 1407-15. Broer PN, Walker ME, Goldberg C, Buonocore S, Braddock DT, Lazova R, Narayan D, Ariyan S. Desmoplastic Melanoma: A 12-Year Experience with Sentinel Lymph Node Biopsy. European Journal of Surgical Oncology 2013, 39(7): 681-5. Lazova R, Laberge GS, Duvall E, Spoelstra N, Klump V, Sznol M, Cooper D, Spritz RA, Chang JT, Pawelek JM. A melanoma brain metastasis with a donor-patient hybrid 21

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34.

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genome following bone marrow transplantation: First evidence in human cancer. PLoS One, 2013; 8(6): e66731. Scortegagna M, Ruller C, Feng Y, Lazova R, Kluger H, Li JL, De SK, Rickert R, Pellecchia M, Bosenberg M, Ronai ZA. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of BrafV600E::Pten–/– melanoma. Oncogene, 2014; 33(34):4330-9. Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, Lazova R, Klump V, Pawelek JM, Xu X, Xu W, Schuchter LM, Davies MA, Herlyn M, Winkler J, Koumenis C, Amaravadi RK. Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma. Journal of Clinical Investigation, 2014; 124(3): 1406-17. Semkova K, Lott JP, Lazova R. Clinicopathologic features and survival in Spitzoid malignant melanoma and conventional malignant melanoma. Journal of the American Academy of Dermatology, 2014; May 15. pii: S0190-9622 (14) 01362-0. doi: 10.1016/j.jaad.2014.04.012. [Epub ahead of print]

Chapters, Books, and Reviews 36. Differential Diagnosis in Dermatopathology II, 2nd edition, Ackerman AB, Guo Y, Lazova R, Kaddu S, Ardor Scribendi, New York, NY, 2000. 37. Lazova R, McNiff JM, Glusac EJ. Under the microscope. Surgeons, pathologists, and melanocytic nevi. Clinics in Plastic Surgery 2000, 27(3): 323-329. 38. Lazova R. Speckled Lentiginous Nevus. Medscape Reference. Updated October 14, 2013. Available at: http://emedicine.medscape.com/article/1061990-overview. 39. Pawelek J, Chakraborty A, Lazova R, Yilmaz Y, Cooper D, Brash D, Handerson, T. Coopting macrophage traits in cancer progression: a consequence of tumor cell fusion? In Infection and Inflammation: Impacts on Oncogenesis, eds. Dittmar T, Zaenker KS and Schmidt A, Contrib. Microbiol, 2006, volume 13: pp. 138-155. 40. Lazova R. Sebaceous neoplasms. In Color Atlas of Dermatopathology, ed. J. GrantKels, CRC Press, Boca Raton FL, 2007, pp. 221-233. 41. Lazova R. Nevus comedonicus. Medscape Reference. Updated May 11, 2012. Available at: http://emedicine.medscape.com/article/1058654-overview. 42. Lazova R. Book review: “ Spitz’s nevus”: Reassessment critical, revision radical, by AB Ackerman, Diana Elish, and Samar Shami. Dermatopathology Practical and Conceptual 2008, volume 14 (1): 360. 43. Miteva M, Lazova R. Spitz nevus and atypical spitzoid neoplasm. Seminars in Cutaneous Medicine and Surgery 2010, 29(3): 165-173. 44. Zayour M, Lazova R. Congenital melanocytic nevi. Clinics in Laboratory Medicine 2011, 31(2): 267-280. 45. Lazova R, Chakraborty A, Pawelek J. Cancer cell fusion with myeloid cells: Implications for energy metabolism in malignant hybrids. In Cell Fusions: Regulation and Control, ed. Lars-Inge Larsson, Springer, 2011, pp. 351-394. 46. Lazova R, Chakraborty A, Pawelek J. Leukocyte-Cancer cell fusion: Initiator of the Warburg effect in malignancy? In Cell Fusion in Health and Disease, eds. Thomas Dittmar and Kurt S. Zanker, Advances in Experimental Medicine and Biology 2011, vol. 950, pp. 151-72.

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47. 48.

Zayour M, Lazova R. Pseudoepitheliomatous hyperplasia. a review. American Journal of Dermatopathology 2011, 33(2): 112-126. Atlas of Practical MOHS Histopathology, Aasi SZ, Leffell DJ, Lazova RZ, Springer New York Heidelberg Dordrecht London, 2013

Peer-Reviewed Educational Materials 49. Lazova R. Spongiotic dermatitis: Web-based lecture for Dermatopathology Master Series, available to physicians worldwide at http://www.mdlive.net/dermpath_sch.htm, 2002 Case Reports, Technical Notes, Letters: 50. Lazova RZ, Sterry JA, Corsetti JP. Pseudoparaproteinemia due to hemoglobinopathy. Clinical Chemistry 1995, 41:1321-1322. 51. Lazova R, Slater C, Scott G. Reactive angioendotheliomatosis. Case report and review of the literature. American Journal of Dermatopathology 1996, 18:63-69. 52. Bolognia JL, Lazova R, Watsky K. The development of lentigines within segmental achromic nevi. Journal of the American Academy of Dermatology 1998, 39:330-333. 53. Lee D, Lazova R, Bolognia JL. A figurate papulosquamous variant of inflammatory vitiligo. Dermatology 2000, 200:270-274. 54. Schaffer JV, Lazova R, Bolognia JL. Partial unilateral lentiginosis with ocular involvement. Journal of the American Academy of Dermatology 2001, 44:387-390. 55. Huynh PM, Lazova R, Bolognia JL. Unusual halo nevi--darkening rather than lightening of the central nevus. Dermatology 2001; 202:324-327. 56. Schaffer JV, Orlow SJ, Lazova R, Bolognia JL. Speckled lentiginous nevus - classic congenital melanocytic nevus hybrid not the result of "collision". Archives of Dermatology 2001, 137:1655. 57. Balfour E, Antaya RJ, Lazova R. Subcutaneous fat necrosis of the newborn presenting as a large plaque with lobulated cystic areas. Cutis 2002, 70:169-173. 58. Balfour E, Zalka A, Lazova R. Cutaneous larva migrans with parts of the larva in the epidermis. Cutis 2002, 69:368-370. 59. Fisher NM, Marsh E, Lazova R. Scar-localized argyria secondary to silver sulfadiazine cream. Journal of the American Academy of Dermatology 2003, 49:730-732. 60. Chavel SM, Taraszka KS, Schaffer JV, Lazova R, Schechner JS. Calciphylaxis associated with acute, reversible renal failure in the setting of alcoholic cirrhosis. Journal of the American Academy of Dermatology 2004, 50 (5 Suppl): S125-128. 61. Chakraborty A, Lazova R, Davies S, Backvall H, Ponten F, Brash D, Pawelek J. Donor DNA in a renal cell carcinoma metastasis from a bone marrow transplant recipient. Bone Marrow Transplant 2004, 34(2): 183-186. 62. Lambert EM, Strasswimmer J, Lazova R, Antaya RJ. Cytomegalovirus ulcer. Successful treatment with valganciclovir. Archives of Dermatology 2004, 140:1199-1201. 63. Yilmaz Y, Lazova R, Qumsiyeh M, Cooper D, Pawelek J. Donor Y chromosome in renal carcinoma cells of a female BMT recipient: visualization of putative BMT-tumor hybrids by FISH. Bone Marrow Transplant 2005, 35(10): 1021-1024. 64. Rahman Z, Lazova R, Antaya RJ. Minocycline hyperpigmentation isolated to the subcutaneous fat. Journal of Cutaneous Pathology 2005, 32(7): 516-519.

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65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79.

Feng J, Gohara M, Lazova R, Antaya RJ. Fatal childhood calciphylaxis in a 10-year-old and literature review. Pediatric Dermatology 2006, 23(3): 266-272. Moss J, Syrengelas A, Antaya RJ, Lazova R. Calcinosis cutis: a complication of intravenous administration of calcium gluconate. Journal of Cutaneous Pathology 2006, 33(2): 60-62. McNiff JM, Subtil A, Cowper SE, Lazova R, Glusac EJ. Reply to letter to editor. Journal of Cutaneous Pathology 2006, 33:764. Poligone B, Christensen SR, Lazova R, Heald PW. Bazex Syndrome (acrokeratosis paraneoplastica). Lancet 2007, 369:530. Kavak A, Ozcelik D, Belenli O, Buyukbabani N, Saglam I, Lazova R. A unique location of nevus sebaceous: labia minora. Journal of the European Academy of Dermatology and Venereology 2008, 22(9): 1136-1138. Koch PE, Lazova R, Rosen JP, Antaya RJ. Urticarial vasculitis in an infant. Cutis 2008, 81(1): 49-52. Reyes CM, Rudinskaya A, Kloss R, Girardi M, Lazova R. Scleroderma-like illness as a presenting feature of multiple myeloma and amyloidosis. Journal of Clinical Rheumatology 2008, 14 (3): 161-165. McGuire L, Lazova R, Tigelaar R, Choate K. What is your diagnosis? Acute herpes simplex virus type 1 stomatitis. Cutis 2009, 83(4): 181,185-186. Knopp E, Diette K, Ko C, Lazova R. Multiple blue macules and papules on the scalp. Archives of Dermatology 2009, 145(10): 1183+1188. Lazova R. Tribute to A. Bernard Ackerman, MD. American Journal of Dermatopathology 2009, 31(8): 771. Galan A, McNiff JM, Choi JN, Lazova R. Fatal HHV6 infection in an immunocompromised patient presenting with skin involvement. Journal of Cutaneous Pathology, 2010; 37:277-281. Terushkin E, Leffell DJ, Futoryan T, Cowper S, Lazova R. Squamoid eccrine ductal carcinoma: A case report and review of the literature. American Journal of Dermatopathology, 2010; 32(3): 287-292. Srisuttiyakorn C, Reeve J, Reddy S, Imaeda S, Lazova R. Subcutaneous histiocytoid Sweet’s syndrome in a patient with myelodysplastic syndrome and acute myeloblastic leukemia. Journal of Cutaneous Pathology, 2014; 41(5): 475-9. Honarpisheh H, Camp R, Lazova R. Staphylococcal purpura fulminans: report of a case. American Journal of Dermatopathology, Aug 5; 2014. [Epub ahead of print] Sue G, Hanlon A, Lazova R, Narayan D. Use of imiquimod for residual acral melanoma. Accepted for publication, British Medical Journal Case Reports, Aug 21; 2014. pii: bcr2014203826. doi: 10.1136/bcr-2014-203826

Scholarship in Press: 80. 81.

Alomari A, Klump V, Neumeister V, Ariyan S, Narayan D, Lazova R. Comparison of the expression of Vimentin and Actin in Spitz nevi and Spitzoid malignant melanomas. Accepted for publication, American Journal of Dermatopathology, 2014. Ibrahim A, Bunick CG, Srivastava B, Lazova R, Ko C, Watsky K. The role of Infliximab in the treatment of superficial granulomatous pyoderma of the head and neck. Accepted for publication, Journal of the American Academy of Dermatology, 2014. 24

Rossitza Lazova, M.D.

82.

Lott JP, Wititsuwannakul J, Lee JJ, Ariyan S, Narayan D. Kluger HM, Lazova R. Clinical Characteristics Associated with Spitz Nevi and Spitzoid Malignant Melanomas: the Yale University Spitzoid Neoplasm Repository Experience, 1991 to 2008. Accepted for publication, Journal of the American Academy of Dermatology, 2014.

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