Community College of Philadelphia Department of Biology Biology 108: Essentials of Human Anatomy and Physiology Course Syllabus Main Campus: Department of Biology Office Room W2-5A Department Head: Dr. Linda Powell Fall / Spring Semester Office Hours: 9:00 A.M.-5:00 P.M. Monday- Friday Summer I / II Semester Office Hours: 9:00 AM - 5:00 PM Monday - Thursday Fax (215) 751-8937 E-mail: [email protected] Web Site: http://faculty.ccp.edu/dept/biol/

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Course Description Biology 108 (3-2-4) The purpose of this course is to provide students with a comprehensive one semester course on the structure and function of the human body. Basic anatomy and physiology of all major organ systems will be covered in lecture and laboratory settings. Lab includes dissection demonstrations by course instructor.

Resources and Materials Text: Marieb, E. Essentials of Human Anatomy and Physiology, Custom Edition for Community College of Philadelphia. San Francisco: Pearson/Benjamin Cummings. Laboratory Manual: Marieb, E. Essentials of Human Anatomy and Physiology, 6th edition. San Francisco: Pearson/Benjamin Cummings. Main Campus Library: First floor Mint building by 17th Street Entrance Fall and Spring Semesters: 8:00 AM to 10:00 PM Monday through Friday 8:30 AM to 5:00 PM Saturday closed on Sunday Summer I and II Semesters: 8:00 AM to 10:00 PM Monday through Thursday closed Friday - Sunday Main Campus West Learning Lab (W3-26): tutoring (for appointment call 215-751-8482) Main Campus Open Lab, W3-45: Microscope, model, and dissected specimen self-study Schedules posted inside and outside each lab or contact instructor. Goggles and gloves - must be worn during specified laboratory activities

College Attendance Policy Students are expected to fulfill their academic obligation by attending all class and laboratory sessions, unless prevented from doing so by illness or other emergency. If a student misses the equivalent of 2 weeks work without an acceptable excuse, the teacher may file an administrative withdraw to remove the student from the class. Individual faculty members have the right to establish attendance regulations, which may include reduced grades for students who miss class and/or laboratory.

College Withdraw Policy A student may withdraw from class without academic penalty up to the eleventh week of the semester. Failure to attend class does not constitute a withdrawal and will result in the assignment of a failing grade. Students who withdraw due to illness or some other emergency should petition the Vice President of Student Affairs for an Excused Withdrawal.

Weather Emergency Numbers In the case of inclement weather, tune to KYW 1060 AM or check www.KYW1060.com for CCP's closing numbers: 238 for day and 2238 for evening and weekend classes.

BIOLOGY DEPARTMENT POLICY ON ACADEMIC DISHONESTY Cheating/Plagiarism - All students are expected to understand what constitutes cheating and plagiarism. The College’s Cheating and Plagiarism Resolution is contained in the Student Handbook, which is available through the Student Life Center located in Room S1-19. Academic Dishonesty A. Cheating behaviors include, but are not limited to: 1. examining or copying another student's answers during a test, exam, or practical 2. examining or copying another student's paper or lab report 3. bringing notes, etc. to class and/or lab during testing (on a scrap of paper, cuffs, etc.) 4. using a dictionary or other source during testing 5. asking someone for the answers to test questions 6. having another person take the test for you 7. stealing or having in your possession without permission, any materials, belonging to or generating from faculty, staff or students B. Aiding another in committing an act of academic dishonesty includes, but is not limited to: 1. willfully offering answers or information related to tests and examinations 2. doing another student's assignment (in or outside of the classroom and/or laboratory) 3. taking a test for another student 4. failing to report knowledge of another student cheating C. Plagiarism includes, but is not limited to: 1. copying from any source without quotation marks and appropriate documentation 2. rewording an idea from a source but omitting documentation 3. having another write for you or copying another student's work 4. having another correct mistakes on your paper (suggested revisions are acceptable)

Faculty Rights: Sanctions available to faculty include, but are not limited to: 1. Requiring the student retake test or rewrite report 2. Drop the item in the calculation of the final grade or provide a substitute item in grading 3. Give the student a zero on the item 4. Drop the student's final grade by one letter 5. Administratively withdraw the student from the course (if before the eleventh week) 6. Give the student a failing grade in the course Student's rights: Student may appeal decisions regarding final grades as per College policy. A copy of student's rights and obligations are available in the Student Handbook.

STUDENT CODE OF CONDUCT Every student is expected to be fully acquainted with and comply with all policies, rules, and regulations outlined in the Student Code of Conduct. The Student Code of Conduct is contained in the Student Handbook, which is published and updated each year. Copies of the Student Handbook are available through the Student Life Center located in Room S1-19.

STUDENTS WITH DISABILITIES Students who believe they may need an accommodation based on the impact of a disability should contact me privately to discuss their accommodation form and specific needs as soon as possible. If you need to request reasonable accommodations, but do not have an accommodation form, please contact the Center on Disability, room BG-39, phone number 215-751-8050

STARFISH CONNECT Starfish Connect is a communication tool for students and faculty. Through Starfish instructors can provide feedback to you about course progress. Throughout the term, you may receive progress emails regarding your academic performance. The emails are designed to be helpful and increase your success in courses. Be sure to open any emails you receive and follow the recommendations. Instructors may also recommend that you contact a specific campus resource, such as the Learning Lab or Counseling Center. If an instructor makes a referral, you may also be contacted directly by this campus service as a follow-up. To access Starfish Connect, simply log into Canvas and click on the link, Starfish Connect. You can even set up a student profile. If you need assistance with Starfish Connect, you can email questions to [email protected]

BIOLOGY DEPARTMENT FINAL EXAMINATION POLICY Your instructor is required to administer a comprehensive final examination during the final week of the semester. The content has been determined by the course committee and can be found in the course outline which follows. This examination will count for at least 15% of your final grade.

Course Learning Outcomes: Upon successful completion of the course students will be able to: 1. Explain the structural organization of the human body. 2. Define and use the appropriate anatomical, physiological and directional terminology when discussing the human body. 3. Explain the concept of homeostasis and describe how homeostatic mechanisms regulate body functions. 4. Identify the major inorganic and organic chemical components of the human body. 5. Identify the basic structures and functions of the cell and its organelles. 6. Identify the 4 tissue types of the human body and describe their functions. 7. Identify the anatomical components of the integumentary, nervous, endocrine, skeletal, muscular, cardiovascular, lymphoid, respiratory, digestive, urinary and reproductive systems. 8. Describe the functions of the integumentary, nervous, endocrine, skeletal, muscular, cardiovascular, lymphoid, respiratory, digestive, urinary and reproductive systems. 9. Describe embryonic and fetal development. 10. Identify a common pathology related to each organ system. 11. Use language/verbal skills that enable patient understanding. 12. Perform specific physiological testing in the laboratory, including enzyme function, osmosis and diffusion, reflex analysis and special sense analysis, blood typing, electrocardiography, blood pressure analysis, spirometry and urinalysis.

Course Outline: The following course outline is only a guide to enable students to master the subject matter. Individual instructors determine what specifics are covered. Instructors also determine grading and evaluation methods. Your instructor is required to provide a written copy of all of her/his policies. 1. Unit 1: Introduction to Anatomy and Physiology, Cells, Tissues and the Integumentary System a. Organization of the human body

i. Levels of organization (AtomsOrganism) ii. Components and functions of organ systems iii. Homeostasis 1. Negative and positive feedback 2. Effects of disease and aging on homeostasis iv. Anatomical position 1. Directional terminology 2. Anatomical regions 3. Anatomical planes and sections 4. Body cavities and serous membranes 5. Abdominopelvic quadrants and regions Clinical application example: medical imaging b. Chemistry overview i. Elements important to the body ii. Atoms and isotopes iii. Chemical bonds: ionic, covalent, hydrogen iv. Chemical reactions 1. Metabolism a. Anabolic reactions b. Catabolic reactions v. Important inorganic molecules 1. Water 2. Acids and bases, pH and buffers 3. Salts vi. Important organic molecules 1. Carbohydrates 2. Lipids 3. Proteins (enzymes) 4. Nucleic acids 5. ATP vii. Clinical application examples: Radioisotopes and medicine; antacids and heartburn; enzyme denaturation with disease/fever c. Cell overview i. Major organelles and functions ii. Plasma membrane 1. Transport mechanisms a. Passive transport: diffusion and osmosis b. Active transport: pumps, exchangers, vesicular transport iii. Protein synthesis iv. Cell cycle v. Clinical application example: Tonicity and the effect on red blood cells d. Tissue overview i. Epithelial tissue 1. Components and general function applicable to all epithelial tissue 2. Specific examples: location and function ii. Connective tissue

1. Components and general function applicable to all connective tissue 2. Specific examples: location and function iii. Muscular tissue 1. Components and general function applicable to all muscle tissue 2. Specific examples: location and function iv. Nervous tissue 1. Components and general function applicable to all nervous tissue 2. Specific examples: location and function v. Four membranes 1. Cutaneous, mucous, serous, synovial vi. Clinical application examples: pathology visualization; hyperplasia e. Integumentary system i. Components of the Integument 1. Skin a. Epidermis and dermis i. Layers, components and functions b. Hypodermis c. Skin color 2. Glands: sweat and sebaceous 3. Hair and nails ii. Clinical application examples: 1. 1st, 2nd and 3rd degree burns 2. Skin cancers: detection and treatments 2. Unit 2: Bones, Joints and Muscles a. Skeletal system i. Overview of functions ii. Bone structure 1. Anatomy of a long bone 2. Osseous tissue 3. Compact bone vs. spongy bone 4. Bone growth and remodeling iii. Clinical application examples: bone fracture and repair; osteoporosis iv. Axial skeleton v. Appendicular skeleton b. Joints i. Fibrous, cartilaginous, synovial 1. structures and movements at each ii. Tendons vs. ligaments iii. Clinical application examples: arthroscopy, joint dislocation c. Muscle tissue i. Overview of three tissue types and basic characteristics 1. Location, function and type of control ii. Skeletal muscle tissue 1. Structure (whole muscle  myofilaments) 2. Events at the neuromuscular junction

3. Excitation-Contraction coupling iii. Skeletal muscle fiber type 1. Sources of energy 2. Clinical application examples: Rhabdomyolysis, tetanus iv. Major skeletal muscles and their actions 3. Unit 3: Nervous System and Endocrine System a. Nervous system i. Overview and divisions 1. CNS vs. PNS 2. Afferent vs. Efferent 3. Autonomic nervous system: Parasympathetic vs. Sympathetic ii. Cells of the nervous system 1. Neurons a. General structure b. Classification 2. Neuroglia a. CNS: microglia, astrocytes, oligodendrites, ependymal cells b. PNS: Schwann cells and satellite cells iii. Electrophysiology 1. Resting, graded and action potentials 2. Action potential propagation 3. Synapses a. Neurotransmitters b. Clinical application example: pain blockers iv. Central nervous system 1. Brain a. Basic anatomical components and functions of each 2. Spinal cord a. Cross-sectional anatomy b. Spinal nerves 3. Meninges a. Locations and functions 4. Cerebrospinal fluid a. Location and functions 5. Clinical application examples: meningitis, spinal taps and epidurals v. Peripheral nervous system 1. Anatomy of a nerve 2. Spinal nerves 3. Cranial nerves 4. Overview of nerve plexuses 5. Reflexes b. Somatic and special senses i. Somatic vs. visceral senses 1. Receptor types overview

2. Pathways overview (from sensation to perception) ii. Special senses: structures and functions 1. Olfaction 2. Gustation 3. Vision 4. Hearing 5. Equilibrium a. Structures and functions c. Endocrine system i. Basic components of the endocrine system ii. Hormones 1. Basic functions 2. Peptide vs. steroid hormones 3. Hormone receptors iii. Hypothalamus and the pituitary gland 1. Anterior lobe 2. Posterior lobe iv. Important endocrine glands/tissues 1. Thyroid gland 2. Parathyroid glands 3. Pancreas 4. Adrenal glands 5. Kidneys 6. Heart 7. Gonads 4. Unit 4: Cardiovascular System and Lymphatics/Immunity a. Cardiovascular system overview i. Components ii. Functions b. Blood i. Components and functions of whole blood 1. Plasma 2. Formed elements: erythrocytes, leukocytes and platelets 3. Hematocrit ii. Erythrocytes 1. Morphology 2. Functions 3. Formation and recycling 4. Blood typing-ABO, Rh 5. Clinical measurements iii. Leukocytes 1. Granulocytes vs. Agranulocytes a. Morphology b. Functions c. Clinical measurements iv. Platelets

1. Hemostasis 2. Clinical measurements c. Heart i. Anatomy 1. Internal vs. external anatomical features 2. Blood flow through the heart 3. Coronary circulation ii. Conducting system 1. Nodal and muscle cells 2. Nervous system control 3. Performing and reading an EKG iii. Cardiac cycle iv. Cardiodynamics v. Clinical application example: myocardial infarction d. Blood vessels i. Structure, function and location of each type of vessel 1. Arteries, arterioles, capillaries, venules, veins ii. Hemodynamics iii. Blood pressure 1. Measurements 2. Regulation iv. Gas exchange at the capillaries 1. Filtration vs. reabsorption v. Clinical application examples: hypertension, atherosclerosis e. Lymphatics overview i. Components and functions of the lymphoid system f. Nonspecific defenses g. Specific defenses i. Cell-mediated immunity ii. Antibody-mediated immunity h. Clinical application examples: autoimmune disorders; immunizations 5. Unit 5: Respiratory System, Digestion and Metabolism a. Respiratory system overview i. Components ii. Functions b. Physiology of breathing: pulmonary function testing c. Gases i. Composition, properties, partial pressures ii. Gas exchange iii. Gas transport iv. Clinical application example: carbon monoxide poisoning d. Control of respiration i. Respiratory acidosis ii. Respiratory alkalosis e. Digestive system overview i. Components

ii. Functions f. Digestive physiology i. Digestion and absorption of carbohydrates, lipids and proteins ii. Digestion and absorption of water, electrolytes and vitamins g. Clinical application examples: gastric bypass surgery, colectomy, colonoscopy, obesity, starvation h. Metabolism i. Carbohydrates ii. Lipids iii. Proteins iv. Absorptive vs. postabsorptive states v. Clinical application examples: lactic acidosis, kwashiorkor 6. Unit 6: Urinary System, Reproductive System, Development a. Urinary system overview i. Components ii. Functions b. Physiology of urine formation i. Filtration ii. Reabsorption iii. Secretion c. Regulation of urine production i. Renal response to acidosis ii. Renal response to alkalosis d. Clinical application examples: kidney stones, urinary tract infection, bladder cancer e. Reproductive systems overview i. Male reproductive system 1. Anatomical structures 2. Physiology a. Semen components and production b. Spermatogenesis 3. Hormonal regulation ii. Female reproductive system 1. Anatomical structures 2. Physiology a. Oogenesis b. Ovarian cycle c. Uterine (menstrual) cycle d. Fertilization and pregnancy e. Lactation f. Menopause 3. Hormonal regulation iii. Clinical application examples: prostate cancer, ovarian cancer, BRCA, HNPCC f. Embryonic development i. Early development

ii. iii. iv. v. vi.

1. Completion of meiosis 2. Formation of zygote 3. Morula and blastocyst formation Implantation Primary germ layers Embryogenesis and fetal development Labor and delivery Clinical application examples: fetal alcohol syndrome, Down syndrome

Tentative Laboratory Schedule Lab Session 1

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Topic/Lab Skill Orientation and Laboratory Safety, Anatomy Overview Cells, Tissues and Integument: Part A  Focusing a light microscope Cells, Tissues and Integument: Part B  Identifying 4 basic tissue types Bones/Articulations Movements/Muscles Lab Skills Assessment Review Lab Skills Assessment 1 Nervous System  Reflexes  Special Senses Testing Cardiovascular System: Part A  Anatomy  Blood Typing  Hematocrit Cardiovascular System: Part B  EKG  Blood Pressure Respiratory System  Spirometry Digestive System  Enzyme function Urinary System and Reproductive System  Urinalysis Lab Skills Assessment 2