COLLEGE OF PHYSICIANS & SURGEONS DEPARTMENT OF ANESTHESIOLOGY ACADEMIC EVENING 2006-2015

Columbia University College of Physicians & Surgeons

Department of Anesthesiology

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18 Annual Academic Evening WEDNESDAY, MAY 20TH, 2015 Heart Hospital Conference Center, 1st Floor, Riverview Terrace ______________________________________________________________

PROGRAM 4:15 PM Poster Exhibit 6:15 PM Oral Presentations 7:30 PM Commentary and Awards

GUEST DISCUSSANT Berend Mets, MB, ChB, PhD, FRCA, FFA (SA) Eric A. Walker Professor and Chair Department of Anesthesiology Penn State Milton S. Hershey Medical Center Hershey, PA

MODERATOR Robert N. Sladen, MBChB, FCCM

CHAIR, PROGRAM SELECTION COMMITTEE Charles W. Emala, MD

ABSTRACT SELECTION COMMITTEE Mitchell F. Berman, MD Jeanine M. D’Armiento, MD, PhD Neil Harrison, PhD Eric J. Heyer, MD, PhD Heidi Jerome, MD H. Thomas Lee, MD, PhD Guohua Li, MD , DrPH Jose Moron-Concepcion, PhD Leila Mei Pang, MD Joachim Scholz, MD Richard M. Smiley, MD, PhD Lena S. Y. Sun, MD Robert A. Whittington, MD Charles W. Emala, MD

ACKNOWLEDGMENTS Cumberland Pharmaceuticals Gauss Surgical, Inc. Corpak MedSystems, Inc.

PREVIOUS ACADEMIC EVENINGS Year

Guest Judge

2014

Jeanine Wiener-Kronish, MD (Harvard Medical School) Kevin Tremper, MD (University of Michigan) Keith Anthony Jones, MD (University of Alabama) Philip Lumb, MBBS, FCCM (Keck School of Medicine, USC) Neal Cohen, MD, MPH, MS, (UCSF) Ronald G. Pearl, MD, PhD (Stanford University) Jonathan Moss, MD (The University of Chicago) Mark F. Newman, MD (Duke University Medical Center) Douglas Coursin, MD (University of Wisconsin) Mark Warner, MD (Mayo Clinic, Rochester, MN) Patricia A. Kapur, MD (UCLA School of Medicine) Peter Glass, MD (SUNY at Stony Brook) David Longnecker, MD (University of Pennsylvania) Simon Gelman, MD (Brigham & Women’s Hospital) John Kampine, MD (Medical College of Wisconsin)

2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000

First Prize May Rabadi, PhD Andrea Miltiades, MD Jennifer Danielsson, MD John G. Gaudet, MD C. David Mintz, MD, PhD Hani Malone, MD C. David Mintz, MD, PhD Christopher Webb, MD Sang Won Park, PhD Steven Yap, MD Sang Won Park, PhD Carmen Guerra, MPH Jennifer Evans Frederick T. Billings, MD Hannah Wunsch, MD Minjae Kim, MD George Gallos, MD Hannah Wunsch, MD George Gallos, M Edmund Jooste, MD Jason Scott, MD Edmund Jooste, MD Yejun Zhao, MD H.T. Lee, MD, PhD

Oral Presentations Finalists 1.

Dexmedetomidine’s inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea: a mechanism that accounts for its clinical benefit during airway irritation. Maya Mikami, Yi Zhang, Charles W Emala

2.

Peptidyl arginine deiminase-4 exacerbates ischemic acute kidney injury by finding NEMO (NFkB Essential Modulator). May Rabadi, Mihwa Kim, Kevin Brown and H.T. Lee

3.

Reduced Middle Cerebral Artery Velocity During Cross-clamp Predicts Cognitive Dysfunction After Carotid Endarterectomy. Joanna L. Mergeche, Samuel S. Bruce, E. Sander Connolly, Eric J. Heyer

4.

Epidemiology of Vasopressor Use Among Adults with Septic Shock in the United States. Emily Vail, Hayley B. Gershengorn, Guohua Li, Hannah Wunsch

5.

A Transcranial Doppler Ultrasonography Finding During Carotid Endarterectomy Produced by a Flap in the Internal Carotid Artery. Alisa Chen, Christopher P Kellner, Robert A Solomon, Eric J Heyer

Poster Presentation Finalists 6.

Drinking during adolescence: Effects of acute and chronic ethanol on dopamine neurons in the ventral tegmental area. E. M. Avegno; A. Mrejeru; M. Salling; D. Sulzer; and N. L. Harrison

7.

Propofol mediated release of nitric oxide from endothelial cells relaxes splanchnic vascular smooth muscle: A potential novel treatment for mesenteric ischemia. Peter D. Yim, George Gallos, Charles W. Emala

8.

Regulating the Spinal Immune Response to Peripheral Nerve Injury: A Role for Trem2 and Primary Somatosensory Neurons. Brendan Smith, John Whang, Eric X. Wei, Ira Schieren, Joachim Scholz

9.

Catheter Failure Rates and Time Course with Epidural versus CSE Analgesia in Labor. Jonathan Groden, Antonio Gonzalez, Jaime Aaronson, Adam Sachs, Richard Smiley

10.

Epidemiology of critical care admissions in a tertiary hospital of sub-Saharan Africa. Meghan Prin, Julia Sobol

11.

Chloroprocaine Spinal Compared to General Anesthesia for Outpatient Knee Arthroscopy – A Retrospective Analysis. Peter Fu, Ryan Ivie, Robert Maniker

Poster Presentations Basic Research 12.

13.

Inflammatory pain dysregulates mu-opioid function in the mesolimbic pathway. WilsonPoe, A.R., Hippolito, L., Yolanda Campos-Jurado, Massaly, N., & Moron-Concepcion, J.A. Resolving the Molecular Composition of Synapses in Central Nociceptive Pathways. Zafeer Baber, Joachim Scholz

14.

Translational approach to the Treatment of COPD. Denzel Woode, Vincent Anguiano, Takayuki Shiomi, and Jeanine D’Armiento

15.

Parenchymal Airspace Profiling to Accurately Distinguish Developmental Abnormalities and Airway Destruction in Animal Models of Lung Disease. Rui Xiao, Takayuki Shiomi, Monica Goldklang, Jeanine D’Armiento

Clinical Research 16.

Perioperative management of patients with left ventricular assist devices undergoing repair of hip fracture. Jason Alexander, Ryan Ivie, Robert Maniker, Julia Sobol

17.

Caudal epidural versus penile block for post-operative analgesia in patients undergoing circumcision with or without chordee repair. Pamela Wendel, Nick Davis

18.

Incidence and associated morbidity and mortality of perioperative aspiration in pediatric inpatients. L. Eisler, M. Sun, C. Ing

19.

Cost analysis of anesthesia-related adverse events during labor and delivery in NewYork State. Tristan D. Hunt, Jean Guglielminotti, Guohua Li

20.

Exploring the effectiveness of traditional vs flipped classroom strategies in fellowship didactics. Rima Rahal, Daniela Darrah

21.

Prevalence of Malignant Hyperthermia Diagnosis in Ambulatory Surgery Center Discharge Records, New York State, 2002-2011. Katherine Lu Zhen, Guohua Li

22.

Comparison of the effect of preoperative meld and meld-na scores on outcome after liver transplantation. T. Lai, G. Wagener

23.

Pulmonary Hypertension in Pregnancy: a retrospective cohort study (19972013). M. Meng, R. Smiley, R. Landau, E. Reitman

24.

Symbiotic Learning: Regional Anesthesiologists Teaching Clinical Correlations in a Gross Anatomy Laboratory for Medical Students. Nicole Spence, Vibhuti Kowluru, Danielle Ludwin Inpatient and Ambulatory MRI Utilization in Pediatric Patients in New York State. Yolanda Y. Huang, Caleb Ing, Lena S. Sun

25.

26.

Analysis of Rhabdomyolysis in Pediatric Surgical Inpatient Admissions Using the KIDS Database. David Maduram, Teeda Pinyavat

27.

Temporal Trends in Anesthesia-related Adverse Events in Cesarean Deliveries in New York State, 2003-2012. Jean Guglielminotti, Cynthia A. Wong, Ruth Landau, Guohua Li

28.

Between hospitals variation in anesthesia-related adverse events during cesarean deliveries in New York State 2009-2011. A patient- and hospital-levels analysis. Jean Guglielminotti, Guohua Li

29.

A Collaborative, Peer-Reviewed, Web-Based Regional Anesthesia Curriculum: Setting a New Standard for Anesthesia Education. Ryan Ivie, Robert Maniker

Case Report Viewing Schedule Monitor A Moderator Gebhard Wagener, MD 4:20 PM Ex Vivo Abdominal Tumor Resection and IMA Reconstruction. Bryan Tischenkel

4:30 PM

Extracorporeal membrane oxygenation as a rescue device for post-reperfusion cardiac arrest during liver transplantation. M. E. Tejani

4:40 PM

Perioperative hemodynamic instability in patients with history of head and neck radiation therapy. Hina Aslam

4:50 PM

Trisomy 18 patient with severe hypoxemia during scoliosis surgery. Howard Teng

5.00 PM

Monitor B Elena ReitmanIvashkov, MD Unanticipated Difficult Airway in a Patient with Herpes Zoster in the Maxillary and Mandibular branches of the Trigeminal Nerve. Namrata Khimani Management of a surgical tracheal tear during laparoscopic transhiatal esophagectomy. Mark Schlangel

Rare cause of EtCO2 loss during sitting craniotomy. Saima Rashid

Airway Management In A Patient With Previous Emergent Cricothyroidotomy and Lidocaine Allergy Presenting For Renal Transplantation. Jerri Chen Anesthetic Seizure versus management of an Subdural Catheter: infant with liver Every Dose is a failure and Test Dose. hypertrophic Lauren D cardiomyopathy for Rosenberg orthotopic liver transplantation. Neil Masters

Monitor C Danielle Ludwin, MD Sciatic Radicular Pain Resulting from a Nontraumatic Inferior Gluteal Artery Aneurysm. Stephen Miller

Brachial plexus block for treatment of crps in previously unaffected limb: does early intervention prevent evolution of symptoms ? Brandon Rock Esenther Bisphosphonates and Calcitonin: Novel Adjunctive treatment for Complex Regional Pain Syndrome in a Pediatric Patient. Michael A. Hershey Long term intravenous ketamine for analgesia in a child with severe graft versus host disease. Jennifer Busse

Combined Bilateral Rectus Sheath and TAP Blocks for Xiphoid to Pubis Incision. Ryan Ivie

Monitor D Jonathan Hastie, MD Intraoperative Management of Patients with Left Ventricular Assist Devices Undergoing Endoscopic Procedures. Dennis Thiel Delayed Myocardial Recovery Requiring Isolated Right Ventricular Assist Device after Inferior Myocardial Infarction. Laura Hannah Bell

Challenging CoreValve Positioning and Deployment during Transcatheter Aortic Valve Replacement. Isaac Y. Wu Pulmonary Artery Rupture Secondary to Pulmonary Artery Catheter Placement and Proposed Algorithm for Management. Rocco Addante

Anesthetic Management of Pediatric Cardiac Transplant Complicated by Inadvertent Rupture of LVAD Cannula. Pamela Wendel

5:10 PM

Smartphones in the Operating Room: Distraction or Diagnostic Aid? A Case of Newly Diagnosed WolffParkinson White in a Pediatric Patient having Bronchoscopy under General Anesthesia. Brandon Esenther Prolonged Duration of Action of Succinylcholine in a Patient with Liver Failure. Sarah Dillon

Use of Draeger Apollo to deliver bilevel positive pressure ventilation for patient with severe COPD during awake frontal craniotomy. Susie So-Hyun Lee

Paravertebral Block for Breast Surgery in a Patient with Primary Lateral Sclerosis. Anthony Fernandes

Temperature Probe Position Confounding Double Lumen Endotracheal Tube Placement for Ventriculopleural Shunt. Jacob Schaff

Eisenmenger Syndrome: A Recent Success. M. Meng

Cardiac herniation after pulmonary wedge resection. Julia Menshenina

5:30 PM

Venous Air Embolus Upon Scalp Incision During Sitting Craniotomy. Nicole Z. Spence

5:40 PM

A customized perioperative care plan for a patient with type 1a glycogen storage disease undergoing elective surgery. Risa Wolk

“Otherwise Healthy…” An Ascending Aortic Aneurysm Diagnosed at Term. Yefim Vilnits Acute Normovolemic Hemodilution for a Jehovah's Witness with Polyhydramnios Presenting for Urgent Cesarean Delivery. Susan Cosgrove

Elective Orthopedic Surgery in Patients with Critical Aortic Stenosis: a Case Report and Review of the Controversy. Holden Groves Intraoperative Endof-Life DecisionMaking In a Patient with Severe Mesenteric Ischemia. Ryan Ivie Accidental Subcutaneous Injection of Rocuronium and the Potential Consequences. Namrata Khimani

5:20 PM

5:50 PM

Embolic Protection Device Placement in a Patient with Ascending Aortic Atherosclerosis on TEE. Peter Downey Transthoracic echocardiography unmasks severe hypovolemia in the setting of high filling pressures. Maggie Chou

When Shunts Attack: Severe Arterial-Venous Shunting on CPB during a Pulmonary Thromboendarte rectomy. William Jackson

Columbia University College of Physicians & Surgeons

Department of Anesthesiology

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17 Annual Academic Evening WEDNESDAY, MAY 28TH, 2014 Heart Hospital Conference Center, 1st Floor, Riverview Terrace ______________________________________________________________

PROGRAM 4:30 PM Poster Exhibit 6:15 PM Oral Presentations 7:15 PM Commentary and Awards

GUEST DISCUSSANT Jeanine Wiener-Kronish, MD Anesthetist-in-Chief Department of Anesthesiology, Critical Care and Pain Medicine Massachusetts General Hospital Henry Isaiah Dorr Professor of Research and Teaching of Anesthetics Harvard Medical School

MODERATOR Robert N. Sladen, MBChB, FCCM

CHAIR, PROGRAM SELECTION COMMITTEE Charles W. Emala, MD

ABSTRACT SELECTION COMMITTEE Mitchell F. Berman, MD Neil Harrison, PhD Eric J. Heyer, MD, PhD Heidi Jerome, MD H. Thomas Lee, MD, PhD Guohua Li, MD , DrPH Jose Moron-Concepcion, PhD Leila Mei Pang, MD Joachim Scholz, MD Richard M. Smiley, MD, PhD Lena S. Y. Sun, MD Robert A. Whittington, MD Charles W. Emala, MD

ACKNOWLEDGMENTS PLATINUM LEVEL SPONSOR Hospira Worldwide, Inc.

GOLD LEVEL SPONSOR 3M United States BiO2 Medical, Inc. Verathon Medical Pulsion Medical, Inc.

SILVER LEVEL SPONSORS Berish Strauch Ltd. Corpak Medsystems, Inc.

PREVIOUS ACADEMIC EVENINGS Year

Guest Judge

2013

Kevin Tremper, MD (University of Michigan) Keith Anthony Jones, MD (University of Alabama) Philip Lumb, MBBS, FCCM (Keck School of Medicine, USC) Neal Cohen, MD, MPH, MS, (UCSF) Ronald G. Pearl, MD, PhD (Stanford University) Jonathan Moss, MD (The University of Chicago) Mark F. Newman, MD (Duke University Medical Center) Douglas Coursin, MD (University of Wisconsin) Mark Warner, MD (Mayo Clinic, Rochester, MN) Patricia A. Kapur, MD (UCLA School of Medicine) Peter Glass, MD (SUNY at Stony Brook) David Longnecker, MD (University of Pennsylvania) Simon Gelman, MD (Brigham & Women’s Hospital) John Kampine, MD (Medical College of Wisconsin) Warren Zapol, MD (Massachusetts General Hospital) Paul Barash, MD (Yale University)

2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998

First Prize Jennifer Danielsson, MD John G. Gaudet, MD C. David Mintz, MD, PhD Hani Malone, MD C. David Mintz, MD, PhD Christopher Webb, MD Sang Won Park, PhD Steven Yap, MD Sang Won Park, PhD Carmen Guerra, MPH Jennifer Evans Frederick T. Billings, MD Hannah Wunsch, MD Minjae Kim, MD George Gallos, MD Hannah Wunsch, MD George Gallos, M Edmund Jooste, MD Jason Scott, MD Edmund Jooste, MD Yejun Zhao, MD H.T. Lee, MD, PhD H.T. Lee, MD, PhD H.T. Lee, MD, PhD

ORAL PRESENTATION FINALISTS 1. Antagonists of the TMEM16A Calcium-Activated Chloride Channel Relax Airway Smooth Muscle and Potentiate β-agonist Relaxation: Potential New Tools to Treat Bronchospasm. Jennifer Danielsson, Matthew B Barajas, Kyra Bernstein, Yi Zhang, George Gallos, Charles W Emala. 2. Peptidylarginine deiminase-4 exacerbates kidney ischemia and reperfusion injury. M. Rabadi, A. Ham, M. Kim, K. Brown and H.T. Lee 3. Cumulative Incidence and Time to Reintubation in United States Intensive Care Units. Andrea N. Miltiades, M.D., May S. Hua, M.D., Hayley B. Gershengorn, M.D., Andrew A. Kramer, PhD, Guohua Li, DrPH, MD, Hannah Wunsch, M.D., M.Sc. 4. The utility of hemodynamic transesophageal echocardiography in clinical decision making in the CTICU. Arun Jayaraman, Maung Hlaing, Brigid Flynn, Robert Sladen. 5. Case Report: Four Patients with Postoperative Delirium following Elective Orthopedic Shoulder Surgery. Pena J, Gaudet JVD, Wilhelm AE, Brown AR, Ludwin D.

POSTER PRESENTATION FINALISTS 6. Chemokines Modulate the Spinal Immune Response to Peripheral Nerve Injury: Functional Consequences for Neuropathic Pain. Brendan Smith, Masayuki Shibasaki, John Whang, Joachim Scholz 7. Calcium activated chloride channels: critical mediators of calcium dynamics in human myometrial cells. Kyra Bernstein BA, Jennifer Danielsson MD, G Thomas Yocum MD, Charles Emala Sr MD, George Gallos MD. 8. Alteration in Gabra4 expression during alcohol withdrawal is mediated by specific microRNAs in the mouse thalamus. R.A. Bekdash; M.S. Salling; N.L. Harrison 9. Urinary neutrophil gelatinase-associated lipocalin (NGAL) is a marker of acute kidney injury in patients undergoing general surgery. Valerie Au, B.S*. and Gebhard Wagener M.D† 10. Postoperative glucose levels and outcome after liver transplantation. Melissa M Grant, BS and Gebhard Wagener, MD 11. Comparison of risk- and reliability-adjusted rates of anesthesia-related complications in labor and delivery. Jean Guglielminotti, Guohua Li.

POSTER PRESENTATIONS LABORATORY RESEARCH 12. Plasticity of Nociceptive Synapses in the Dorsal Horn of the Spinal Cord after Peripheral Nerve Injury. Chi-Kun Tong, Fang Yang, Dag Schädlich, John Whang, Zafeer Baber, Susan J. Tappan, Patrick R. Hof, Joachim Scholz. 13. Acetaldehyde, not Ethanol, impairs myelin formation and viability in primary mouse Oligodendrocytes. David J.C. Coutts and Neil L. Harrison 14. Dexmedetomidine’s inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea. Maya Mikami, Yi Zhang, Charles W Emala. 15. Reduction of Ih in prefrontal pyramidal neurons following adolescent alcohol consumption. Salling, MC, Avegno EA, Harrison NL 16. Modulation of cholesterol efflux through treatment with an LXR agonist in cigarette smoke induced emphysema in mice. Sklepkiewicz P, Kaur R, Goldklang M, Trischler J, Rauschkolb P, Zelonina T, Tall A, D’Armiento JM.

17. Analgesic Treatment with Pregabalin Does Not Prevent Persistent Pain After Peripheral Nerve Injury in the Rat. John Whang (1) and Fang Yang (1), William T. Derry (2,3), Daniel Vardeh (2,4), Joachim Scholz (1) 18. Genetic Deletion of the GABAA α4 Subunit Leads to Increased Airway Resistance and Inflammation. Gene T. Yocum MD, Damian L. Turner PhD, Jennifer Danielsson MD, Matthew B. Barajas BS, Gregg E. Homanics PhD, Charles W. Emala MD MS. 19. Lymphangiomyomatosis - a disease of mesenchymal progenitor cells. Anguiano, V. Shiomi, T, Chada, K. and D’Armiento, J.

CLINICAL RESEARCH 20. General Anesthesia and Endotracheal Intubation Experience from an Academic Labor & Delivery Service. Adam Sachs, MD, Richard M. Smiley, MD, PhD. 21. Trends in Anesthesiology Research: An Unsupervised Topic Model of the ASA Annual Meeting Abstracts. Alexander Rusanov, MD, Chunhua Weng, PhD. 22. Association between Travel Time and Rehospitalization at a Different versus the Same Hospital for Survivors of Critical Illness. Andrea Miltiades, MD, Hannah Wunsch, MD, MSc, May Hua, MD. 23. Improving Data Acquisition for ICU Bed Flow Management. Dimitris Giannaris, MD, Michele Lerch, FACHE, Robert N. Sladen, MBChB, FCCM 24. Relationship between height and outcomes among critically ill adults. Emily Vail, MD, David Harrison, PhD and Hannah Wunsch, MD, MSc 25. The myth of the untested catheter - epidural vs. combined spinal epidural (CSE). Jaime Aaronson, MD, Adam Sachs, MD, Antonio Gonzalez, MD, Richard M. Smiley, MD, PhD. 26. Neutrophil-Lymphocyte Ratio as a Predictor of Cognitive Dysfunction in Carotid Endarterectomy Patients. Kaitlin A. Mallon, BA; Hadi J. Halazun, MD; Joanna L. Mergeche, BA; E. Sander Connolly, MD; Eric J. Heyer, MD, PhD. 27. Continuous Spinal Labor Analgesia and Maternal Fever. Marie-Louise Meng, Richard Smiley, Allison Lee 28. Prophylactic ondansetron for the prevention of intrathecal fentanyl- or sufentanil-mediated pruritis: a meta-analysis. Meghan Prin MD, Vivek Moitra MD, Jean Guglielminotti MD PhD, Guohua Li MD DrPh. 29. Radial pulse pressure dose not decrease compared to femoral pulse pressure with caval cross clamping and vasopressor use during liver transplantation. Nina T Yoh MS, Keerthana Natarajan Engineer, Ramakrishna Mukkamala PhD, Gebhard Wagener, MD. 30. Trends in Shared Decision Making: Implications for Chronic Pain Patients. Sascha Qian, MD, Nomita Sonty, PhD. 31. Desperate times call for desperate measures: designing controlled trials for new therapies in sepsis. Meghan Prin MD, Gebhard Wagener MD

CASE REPORTS MONITOR A 32. Elective Extracorporeal membrane oxygenation in a laboring parturient with Eisenmenger’s Syndrome. Adam Sachs, MD, Richard M. Smiley, MD, PhD. 33. Severe bradycardia during laryngoscopy in a 5 year old girl with hypertrophic cardiomyopathy and cardiofaciocutaneous syndrome. Albert Lin, Anjalee Dave, Tatiana Kubacki

34. Ruptured Ectopic Pregnancy in a patient with DiGeorge Syndrome and Tetralogy of Fallot. Andrea Miltiades, MD, Sarah Smith, MD, Minjae Kim, MD 35. The Perils of Polymyxin Therapy: Polymyxin Induced Polyuria and Neuromuscular Blockade. Babar Fiza, MD, Vivek Moitra, MD. 36. Altered Response to Opioids in Patient on Induction Antiretrovirals. Brandon Rock Esenther, MD, Steven Miller, MD. 37. Kyphoplasty for a Vertebral Compression Fracture in Patient with Solid Organ Transplant. Cameron Marshall, MD, David Bandola, MD. 38. Cesarean delivery in a patient on extracorporeal membrane oxygenation for acute respiratory distress syndrome. Jaime Aaronson, MD, Richard M. Smiley, MD, PhD.

MONITOR B 39. Leukemoid Reaction after acute hemorrhage. David Kiamanesh, MD, Hannah Wunsch, MD, Vivek Moitra, MD. 40. Recurrent Central Sensitization, Potential for Development of Chronic Pain and Importance of Preventive Analgesia. Febin Melepura, MD, Anis Dizdarevic, MD. 41. Intraoperative Diagnosis and Management of Transfusion-Related Acute Lung Injury (TRALI): A Case Report. Lisa Lynch MD, Neeta Saraiya MD, Robert Kazim MD 42. Respiratory failure secondary to systemic inflammatory response in post-Alemtuzumab immunosuppression induction: A tale of two kidney transplant recipients. Namrata Khimani MD, Victor Lan MD, Steven Miller MD 43. A Case of Episodic Hemodynamic Instability in a Patient with a History of Graves’ Disease. Obinna Orji MD, Nicole Robinson-Taylor MD, Parwane Pagano MD 44. Perioperative Extrapyramidal Reaction to Ondansentron. Zafeer Baber, M.D., Sansan Lo, M.D. 45. ARDS: What to do when you do not have ECMO? Gurwinder Gill, MD, Gebhard Wagener, MD

MONITOR C 46. Rare Leiomyosarcoma of the Right Internal Iliac Vein Metastatic to the Right Heart. Angela C. Lee, MD, Sansan Lo, MD. 47. A Unique Approach to the Surgical Management of Aortic Insufficiency in Patients With a Heartmate II LVAD: A Case Report. Vibhuti Kowluru MD and Jeremy S. Poppers MD PhD 48. Monitored anesthesia care for subclavian venous-arterial extracorporeal membrane oxygenation (VA ECMO) cannulation. Jason Fu, MD, Bessie Kachulis, MD 49. A Multidisciplinary Approach to a LVAD-Arrest Algorithm: A Case Report and an Institution’s Response. E Grawe, MD, P Colombo, MD, M Yuzefpolskaya, MD, H Takayama, MD, PhD, N Uriel, MD, K Mody, MD, N Hoi-Yun Yip, MD, M Flanery, FNP, M Lurch, RN, S. Goswami, MD, MPH. 50. Coronary Obstruction and Cardiogenic Shock Requiring PCI and VA ECMO following Deployment of a Transcatheter Aortic Valve. Erin Grawe, MD, Taylor Johnston, MD, and Bessie Kachulis, MD. Columbia University/New York Presbyterian Hospital, Department of Anesthesiology. 51. VV-ECMO cannulation of an Avalon bicaval dual lumen catheter for a patient with severe status asthmaticus. Melissa Lee, MD, Susan Lei, MD. 52. Echo To the Rescue: Indispensable TEE in ICU Care. Jennifer McDonald, MD, Gebhard Wagener, MD.

MONITOR D 53. Addition of Short-Acting Distal Popliteal Sciatic Block to Long-Acting Mid-Thigh Sciatic Block Provides Fast Onset and Prolonged Duration. Armand Wilhelm, MD, Robert Maniker, MD. 54. Mitochondrial Myopathy, Encephalopathy, Lactic acidosis and Stroke‐Like Episodes (MELAS) Syndrome Undergoing Intertrochanteric ORIF. Asif Neil Mohammed MD, San San Lo MD 55. MRI negative acute paraplegia after spinal cord stimulator placement under monitored anesthesia care. Jacob Schaff, MD, Christopher Winfree, MD, John G Gaudet, MD. 56. “Should We Give Intralipid?” – A Case of Possible Local Anesthetic Toxicity. Lauren Parnell-Cassidy, MD, Danielle Ludwin, MD. 57. Prolonged Continuous Spinal Anesthesia for Post-Operative Pain Management in a Chronic Pain Patient. Lisa Kilcoyne, MD., Anis Dizdarevic MD., Robert Maniker, MD., Connie Chung, MD. 58. Interscalene Block and Permanent Phrenic Nerve Paresis: Is It Preventable? Tanzina Khan, MD, MPH, Matthew R. Kaufman, M.D., F.A.C.S., Anthony Robin Brown, MBChB, FFA. 59. Successful Spinal Anesthesia in an Adult Patient with Juvenile Rheumatoid Arthritis, Short Stature, and Low Body Mass. Vibhuti Kowluru, MD, Robert Maniker, MD.

CASE REPORT VIEWING SCHEDULE Monitor A Elena ReitmanIvashkov, MD 32. Elective Extracorporeal membrane oxygenation in a laboring parturient with Eisenmenger’s Syndrome. Adam Sachs, MD.

Monitor B Monitor C Oliver Panzer, MD Jonathan Hastie, MD 39. Leukemoid 46. Rare Reaction after Leiomyosarcom acute hemorrhage. a of the Right David Kiamanesh, Internal Iliac MD. Vein Metastatic to the Right Heart. Angela C. Lee, MD

4:45 PM

33. Severe bradycardia during laryngoscopy in a 5 year old girl with hypertrophic cardiomyopathy and cardiofaciocutaneo us syndrome. Albert Lin, MD

40. Recurrent Central Sensitization, Potential for Development of Chronic Pain and Importance of Preventive Analgesia. Febin Melepura, MD.

47. A Unique Approach to the Surgical Management of Aortic Insufficiency in Patients With a Heartmate II LVAD: A Case Report. Vibhuti Kowluru MD.

5:00 PM

34. Ruptured Ectopic Pregnancy in a patient with DiGeorge Syndrome and Tetralogy of Fallot. Andrea Miltiades, MD.

41. Intraoperative Diagnosis and Management of TransfusionRelated Acute Lung Injury (TRALI): A Case Report. Lisa Lynch MD.

48. Monitored anesthesia care for subclavian venous-arterial extracorporeal membrane oxygenation (VA ECMO) cannulation. Jason Fu, MD.

5:15 PM

35. The Perils of Polymyxin Therapy: Polymyxin Induced

42. Respiratory failure secondary to systemic inflammatory

49. A Multidisciplinar y Approach to a LVAD-Arrest

Moderato r 4:30 PM

Monitor D Danielle Ludwin, MD 53. Addition of Short-Acting Distal Popliteal Sciatic Block to Long-Acting Mid-Thigh Sciatic Block Provides Fast Onset and Prolonged Duration. Armand Wilhelm, MD. 54. Mitochondrial Myopathy, Encephalopathy , Lactic acidosis and Stroke‐Like Episodes (MELAS) Syndrome Undergoing Intertrochanteri c ORIF. Asif Neil Mohammed MD. 55. MRI negative acute paraplegia after spinal cord stimulator placement under monitored anesthesia care. Jacob Schaff, MD. 56. “Should We Give Intralipid?” – A Case of Possible

Polyuria and Neuromuscular Blockade. Babar Fiza, MD.

response in postAlemtuzumab immunosuppressio n induction: A tale of two kidney transplant recipients. Namrata Khimani MD, Victor Lan MD. 36. Altered 43. A Case of Response to Episodic Opioids in Patient Hemodynamic on Induction Instability in a Antiretrovirals. Patient with a Brandon R. Esenther, History of Graves’ MD. Disease. Obinna Orji MD, Nicole Robinson-Taylor MD.

Algorithm: A Case Report and an Institution’s Response. Erin Grawe, MD.

Local Anesthetic Toxicity. Lauren Parnell-Cassidy, MD.

50. Coronary Obstruction and Cardiogenic Shock Requiring PCI and VA ECMO following Deployment of a Transcatheter Aortic Valve. Erin Grawe, MD

57. Prolonged Continuous Spinal Anesthesia for Post-Operative Pain Management in a Chronic Pain Patient. Lisa Kilcoyne, MD.

5:45 PM

37. Kyphoplasty for a Vertebral Compression Fracture in Patient with Solid Organ Transplant. Cameron Marshall, MD.

44. Perioperative Extrapyramidal Reaction to Ondansentron. Zafeer Baber, M.D.

58. Interscalene Block and Permanent Phrenic Nerve Paresis: Is It Preventable? Tanzina Khan, MD, MPH.

6:00 PM

38. Cesarean delivery in a patient on extracorporeal membrane oxygenation for acute respiratory distress syndrome. Jaime Aaronson, MD.

45. ARDS: What to do when you do not have ECMO? Gurwinder Gill, MD.

51. VV-ECMO cannulation of an Avalon bicaval dual lumen catheter for a patient with severe status asthmaticus. Melissa Lee, MD. 52. Echo To the Rescue: Indispensable TEE in ICU Care. Jennifer McDonald, MD.

5:30 PM

59. Successful Spinal Anesthesia in an Adult Patient with Juvenile Rheumatoid Arthritis, Short Stature, and Low Body Mass. Vibhuti Kowluru, MD.

Department of Anesthesiology 16th Annual Academic Evening Wednesday, May 29th 2013 173 Fort Washington Avenue, Heart Center, Riverview Terrace Guest Judge: Kevin Tremper, M.D., Ph.D. Robert B. Sweet Professor and Chair Department of Anesthesiology, University of Michigan ORAL PRESENTATION FINALISTS 1. Novel chloride channel blockers relax airway smooth muscle: potential new tools to treat bronchospasm. Jennifer Danielsson, A. Rinderspacher, W. Fu, Y. Zhang, D. W. Landry, C. W. Emala. 2. Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury. Ahrom Ham, Mihwa Kim, Joo Yun Kim and H. Thomas Lee. 3. Rotational thromboelastometry (ROTEM) predicts thromboembolic complications after major surgery. Alexander Hincker BA, Justin Feit, Robert N. Sladen MD and Gebhard Wagener MD. 4. Pressure Management during Carotid Endarterectomy & Early Cognitive Dysfunction. John G. Van Driest, MD; Joanna L. Mergeche, BA; Zirka H. Anastasian, MD;Minjae Kim, MD; E. Sander Connolly, MD; Eric J. Heyer, MD, PhD. 5. Concomitant use of inhaled nitric oxide and high flow nasal cannula to facilitate extubation in a cardiac surgery patient with severe right ventricular failure. Cosmin Gauran, Sumeet Goswami. POSTER PRESENTATION FINALISTS 6. Alcohol withdrawal alters gabra4 expression, microRNA gene expression profile and excitability in cultured mouse cortical neurons. R. A. Bekdash, M.W. Nason, N.L. Harrison. 7. Enhanced protein phosphatase 2A (PP2A) activity drives SK2 channel mediated impairment of long term potentiation (LTP) in the hippocampus after context-dependent sensitization to morphine. A.K. Fakira, G.P. Portugal, Z. Meylan and J.A. Morón Concepcion. 8. Nerve injury-induced neuronal cell death in the dorsal horn of the spinal cord contributes to chronic neuropathic pain. Moll, Inquimbert, Latremoliere, Yang, Whang, Yoo, Yanagawa, Hof, Scholz. -Agonist-Induced Relaxation of Airway Smooth Muscle. E.A. Townsend, PhD, Y. Zhang MD, C. Xu, Ryo Wakita, PhD, DDS, C.W. Emala MS, MD.

10. The Generalizability of Randomized Controlled Trials in Critical Care Medicine An International Multi-Center Pilot Study of Eligibility Criteria. Ivie R, Wunsch H, Goldklang MP, Sittambalam C, Fowler R, Moitra VK. 11. Total bilirubin as a predictor of mortality after cardiac surgery. Meghan Kirksey MD, Gebhard Wagener, MD. 12. Effect of Donor Quality on Transfusion Requirements during Liver Transplantation. Teresa A. Mulaikal MD, Nanshi Sha BS, Gebhard Wagener MD. POSTER PRESENTATIONS LABORATORY RESEARCH 13. Effects of the transient receptor potential (TRP) V1 antagonist, capsazepine, on airway smooth muscle function. Gene T. Yocum, M.D., Elizabeth A. Townsend, Ph.D., Yi Zhang, M.D., Charles W. Emala, M.D. 14. BK channel modulation in the treatment of experimental asthma. MP Goldklang, JF Perez-Zoghbi, J Trischler, T Nkyimbeng, SI Zakharov, T Shiomi, T Zelonina, AR Marks, SO Marx, JM D’Armiento. 15. A novel strategy to treat human pre-term labor - targeting the TMEM16/anoctamin chloride channel in human pregnant uterus. Peter Yim MD, Wen Fu, PhD, Elizabeth Townsend PhD, Hiromi Funayama DDS, PhD, George Gallos, MD. 16. Plasticity of Nociceptive Synapses in the Dorsal Horn of the Spinal Cord after Peripheral Nerve Injury. Fang Yang, Dag Schädlich, John Whang, Rohini Kuner, Anke Tappe, Susan Tappan, Patrick R. Hof, Joachim Scholz. 17. A new role for spinal cord SK-channels in chronic inflammatory pain. L. Hipólito*, A.K. Fakira*, J.A. Morón Concepción and Z. Melyan. 18. Effects of chronic pain on opiate addiction: Behavioral and neurochemical mechanisms. Lucia Hipolito, Laszlo Virag, Robert Whittington, Sandra Comer, Jose A. Moron Concepcion. 19. Familiar receptors in unusual places: AMPAR expression in keratinocytes. D. Cabañero, T. Irie, M.E. Ruiz, D.M. Owens, J. Morón-Concepción. 20. Strychnine-sensitive glycine receptors mediate tonic inhibition in layer II/III pyramidal neurons of the medial prefrontal cortex. Salling, MC, Harrison, NL. CLINICAL RESEARCH 21. Reduced Middle Cerebral Artery Velocity during Cross-Clamp Predicts Cognitive Dysfunction after Carotid Endarterectomy. Joanna L. Mergeche, BA; Samuel S. Bruce, MA; E. Sander Connolly, MD;Eric J. Heyer, MD, PhD. 22. Atropine Dose and Bradycardia During Electroconvulsive Therapy. Nayema Khan B.S.; Eric J. Heyer M.D., Ph.D., Mitchell F. Berman M.D., M.P.H. , Eugene Ornstein, M.D. , Joshua A. Berman M.D., Ph.D. and Zirka H. Anastasian M.D.

23. Implementation of a Multidisciplinary Action Group in the Intensive Care Unit. Lance M. Retherford, MD; Robert N. Sladen, MBChB, FCCM. 24. Evaluation of Hypercoagulability via ROTEM Thromboelastography after Ventricular Assist Device Implantation. Maung Hlaing MD, Alexander Hincker BA, Justin Feit, Robert Sladen MD, Gebhard Wagener MD. 25. The Double Envelope Overestimates the Aortic Valve Area in Severe Aortic Stenosis by Tranesesophageal Echocardiography. Elrond Teo, Rebecca Hahn, Jack Shanewise. 26. Acute kidney injury after pediatric liver transplantation. Vanessa Cowan MD, Gebhard Wagener MD. 27. Altruistic Unbalanced Paired Kidney Exchange: Survey of Attitudes of Transplant Professionals. Vanessa Cowan, MD, Lloyd Ratner, MD. 28. Relationship between early post-operative fever and risk of infection in critically ill patients. Tzevan Poon, MD; Hayley Gershengorn, MD; Hannah Wunsch, MD MSc. 29. Characterizing Patients Admitted to Stepdown Units in the United Kingdom. Meghan Prin, Kathryn Rowan, Hannah Wunsch. 30. Incidence of severe intraoperative desaturation and bradycardia in pediatric pulmonary hypertension patients. Lisa Eisler, M.D., Minjae Kim, M.D., Teeda Pinyavat, M.D., Jeffrey Gross, Mitchell F. Berman, M.D., Caleb Ing, M.D. 31. Sick Patients Have More Data: The Incompleteness of Electronic Health Rerecord Data Creates Bias. Alexander Rusanov MD, Nicole G. Weiskopf MA, Charles Emala MD and Chunhua Weng PhD. 32. Cost-effectiveness analysis of stocking dantrolene in ambulatory surgery centers. Barbara H. Lang, Taiwo Aderibigbe, Henry Rosenberg, Guohua Li. 33. Predictors of Outcomes in Patients with Spinal Stenosis Who Received Epidural Steroid Injections; a Study Design. Brandon Sorensen, M.D. David Bandola, M.D. 34. Why Did It Take That Long? A Study of Factors Influencing Cesarean Delivery Times. Gonzalez, Antonio MD, Meng, Marie-Louis, MD, Kim, Minjae MD, Smiley, Richard MD, PhD. 35. Utility of Electronic Teaching Aids for Medical Student Education in the OR. Namrata Khimani MD, Allen Friedman MD, Saundra Curry MD. CASE REPORTS Monitor A 36. Resection of Paraganglioma in a Patient with Previous Mustard Atrial Switch Procedure. Alan Ho MD, Jeremy Poppers MD, PhD. 37. Paradoxical hemodynamic collapse after subxiphoid pericardial window. Benita Liao, MD MPH, Sansan S. Lo MD.

38. Domino liver transplantation using a liver with familial amyloid polyneuropathy. Mark Schlangel MD, MBA, Brigid Flynn MD. 39. Anesthetic implications of extended right hepatectomy in a patient with Fontan physiology: A Case report. Paul David Weyker MD, Taylor Johnston MD. 40. Veno-Venous and Veno-Arterial Extracorporeal Membrane Oxygenation After Implantation of Total Artificial Heart and Massive Transfusion. Brian W. Nicholas MD, Jessica Spellman MD. 41. The Development and Presentation of a Thoracic Epidural MRSA Abscess Following Epidural Catheter Placement for Resection of Thymic Mass. Cameron Marshall MD, Anis Dizdarevic MD. 42. Coronary Artery Bypass Grafting in a Patient with Severe Hypothyroidism. Jacob E. Schaff MD, Maninder Singh MD. 43. An Overview of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemoperfusion for the Anesthesiologist. Christopher Webb, MD, Richard Raker MD. 44. Succinylcholine-Induced Rhabdomyolysis in a Febrile Patient. Neha Patel MD, Vivek Moitra, MD. Monitor B 45. Preterm Cesarean Delivery in a Parturient with Candida Parapsilosis Endocarditis: A Case Report. Jason Fu MD, Lance Retherford MD, Brigid Flynn MD. 46. A Parturient with a Possible Pheochromocytoma, Von Hippel-Lindau Disease and Preeclampsia. Marie-Louise Meng MD, Stephanie Goodman, MD. 47. Type II Von Willebrand Disease and Known Difficult Airway in a Twin Pregnancy. Ryan MJ Ivie MD, Stephanie Goodman, MD. 48. Thoracic Endometriosis – A Rare Cause of Pneumothorax in a Patient Requiring VATS. Ryan MJ Ivie MD, Sansan Lo, MD. 49. Anesthetic evaluation and management of a patient with thoracic endometriosis syndrome presenting for elective surgery. Garret Weber MD, Christopher Webb MD, Richard Raker MD. 50. Left stellate ganglion block for the treatment of ischemic ventricular tachyarrhythmias in two patients requiring biventricular assist devices for cardiogenic shock after myocardial infarction. Emily A. Vail MD, Barry Fine MD, PhD, Staffan Wahlander MD, Michael Weinberger MD. 51. Severe Restrictive Lung Disease Complicating Robotic-Assisted Laparoscopic Prostatectomy. Emily Vail MD, Ryan MJ Ivie MD, Meghan Prin MD and Richard Raker MD. 52. Impact of Subanesthetic Ketamine Infusion on Mood in a Critically Ill Patient. Daniela Darrah MD, Vivek Moitra MD. Monitor C 53. Continuous Spinal Anesthesia (CSA) Technique for Aortic Stenosis: A Case Report. Maricela Sanchez MD, Danielle Ludwin MD.

54. Sudden, profound hypotension under interscalene nerve block during arthroscopic shoulder surgery in the beach chair position. Irvin Sanchez MD, Anthony R. Brown MBChB, FFA(SA). 55. An interesting case of intravenous lidocaine infusion in the management of chronic neuropathic pain related to idiopathic small fiber peripheral neuropathy. George Christolias MD, Leena Mathew MD. 56. Differential Diagnosis of Headache Following Epidural Steroid Injection: Pathophysiology, Diagnosis and Management. Kristoffer Padjen MD, PhD, Anis Dizdarevic MD. 57. Submental Intubation: An Alternative to Tracheostomy in Maxillofacial Trauma. Macdale Elwin MD, Parwane Pagano MD. 58. Successful Strategy of Glidescope/Nasal Bougie Guided Intubation of Patient with Extreme Supraglotic Edema. Robert Kong, Peter Yim, Christine Boxhorn, Terrance Lai, Hardik Doshi (ENT), Anis Dizdarevic, Parwane Pagano, Robert Maniker. 59. The ethical considerations of Left Ventricular Assist Device (LVAD) as destination therapy in a child diagnosed with dilated cardiomyopathy (DCM) and Duchenne’s Muscular Dystrophy (DMD). L. Volz MD, M. Tresgallo MS, MPH, DNP, M. Carley MD,G. Hardart MD, MPH, A. Addonizio MD, W. Schechter MD. 60. Perioperative Management of a Pediatric Patient with Shone’s Syndrome During Mitral Valve (MV) Replacement with a Melody Valve. Matthew Monteleone MD, William Schechter MD. Monitor D 61. Tamponade in a Patient with a Total Artificial Heart. Elrond Teo MD, Jeremy Poppers MD. 62. Pulmonary Tension Associated with McConnell’s Sign. Elrond Teo MD, Steven Miller MD. 63. Intraoperative Diagnosis of SVC Syndrome After Heart Transplant. Daewha Benjamin Hong MD, Jonathan Hastie MD. 64. Complex Pulmonary Artery Reconstruction Requires Crash Bypass and VA ECMO. Robert Nampiaparampil MD, Taylor Johnston MD, Jeremy Poppers MD. 65. Resuscitation of a 46 Year Old Woman with HeartMate II LVAD: Two Resuscitations, Two Outcomes. Lance M. Retherford, MD, Steven Miller, MD, Robert N. Sladen, MBChB, FCCM 66. Use of Nasally-Inserted Disposable TEE Probe to Diagnose Unsuspected Right Ventricular Failure. Lance M. Retherford, MD, Staffan Wahlander, MD, Robert N. Sladen, MBChB, FCCM 67. Successful use of inhaled nitric oxide in management of critical pulmonary hypertension as observed in real time with a disposable ImaCor hTEE probe. Meghan Kirksey MD, PhD, Robert N. Sladen, MBChB, FCCM

68. Syncardia TAH delayed bleeding and possible tamponade. Cosmin Gauran MD, Gebhard Wagener MD 69. Heartware biventricular assist device as bridge to heart transplant. Issa Toure MD, Gebhard Wagener MD.

Department of Anesthesiology 15th Annual Academic Evening Wednesday, May 30th 2012 173 Fort Washington Avenue, Heart Center, Riverview Terrace Guest Judge: Keith Anthony Jones, M.D. Alfred Habeeb Professor and Chair, Department of Anesthesiology University of Alabama School of Medicine, Birmingham, AL

ORAL PRESENTATION FINALISTS 1. Anesthetic agents disrupt the growth cone response to guidance cues via a GABAA receptor mechanism. C.D. Mintz, K. Barrett, and N.L. Harrison. 2. Isoflurane post-conditioning induces 5’-ectonucleotidase (CD73) to protect against renal ischemia and reperfusion. A. Ham, M. Kim, J.Y. Kim, and H.T. Lee. 3. Polymorphisms of inflammatory mediators increase the risk of post-operative neurocognitive dysfunction following carotid endarterectomy. H. Malone, E.J. Heyer, E.S. Connolly, J.L. Mergeche, I.S. Kotchetkov, Z.H. Anastasian, D.O. Quest, R.A. Solomon, G.J. Todd, A. Benvenisty, J.F. McKinsey, N. Morrissey, and R. Nowygrod. 4. Aminocaproic acid versus Aprotinin: Current blood transfusion trends in pediatric cardiac surgery. T.A. Chambers, J. Koenigsberg, B. Thumm, A. Clapcich, and L. Sun. 5. Known Hemidiaphragmatic Paresis and Contralateral Interscalene Block - Absolute Contraindication? T. Dickson and D. Ludwin.

POSTER PRESENTATION FINALISTS 6. Effects of Ginger (Zingiber officinale) and its Constituents On Airway Smooth Muscle Relaxation And Calcium. E. Townsend, M.E. Siviski, Y. Zhang, and C.W. Emala. 7. A role for AMPAR consisting of GluA4 subunits in Opioid-Induced Hyperalgesia. D. Cabañero, Z. Melyan, A. Baker, S. Zhou, G.L. Hargett, Y. Xia, H. Beaudry, L. Gendron, S.M. Carlton, and J.A. Morón-Concepción. 8. Different mechanisms underlying morphine-induced behavioral responses and alterations in synaptic plasticity. A.K. Fakira, B. Carusillo, Z. Meylan and J.A. MorónConcepcion. 9. Charlson Comorbidity Score and Maternal Mortality: A Case-Control Study. J.M. Todaro, J. Brady, and G. Li. 10. Cesarean Section Increases Risk of Rehospitalization in the One Year Postpartum Period: A Retrospective Cohort Study. W. M. Jackson, J. Brady, X. Mao, P. Flood, and G. Li. 11. Problem Solving Appraisal and Dispositional Affect Contribute to Pain-Related Adaptation. J. Conrath, M. Gittleman, and N. Sonty.

POSTER PRESENTATIONS LABORATORY RESEARCH 12. Fetal alcohol alters the histone marks H3K4me3 and H3K9me2 along the proopiomelanocortin gene in the arcuate area of the hypothalamus. R. A. Bekdash, W.J. Belden, and D.K. Sarkar. 13. Serotonergic regulation of negative symptoms in schizophrenia. M.W. Nason Jr, C. Kellendonk, and N.L. Harrison. 14. Plasticity of Nociceptive Synapses in the Dorsal Horn of the Spinal Cord after Peripheral Nerve Injury. F. Yang, D. Schädlich, E. Alverson-Banks, B. Quach, R. Kuner, A. Tappe, and J. Scholz. 15. Targeting Uterine Smooth Muscle TMEM16 Calcium Activated Chloride Channels to Suppress Oxytocin Induced Contractions and Calcium Handling. M. Siviski, H. Funayama, W. Fu, R. Smiley, C.W. Emala, and G. Gallos. 16. Glutamatergic transmission in the hippocampus and amygdala plays a critical role in the rewarding properties of morphine. G.S. Portugal, R. Hasani, M. Bruchas, and J.A. Morón Concepcion. 17. New therapeutic strategy to prevent morphine tolerance during chronic inflammatory pain. L. Hipólito, H. Beaudry, L. Gendron, and J.A. Morón Concepción. 18. Mechanism of morphine-induced sensitization: a new key player – small-conductance potassium cannel. Z. Melyan, A.K. Fakira, G.S. Portugal, B. Carusillo and J.A. Morón Concepción.

CLINICAL RESEARCH 19. Statin Therapy Is Associated with Improved Cognitive Performance in Patients Having Carotid Endarterectomy. J.L. Mergeche, E.J. Heyer, S.S. Bruce, Z.H. Anastasian, D.O. Quest, R. A. Solomon, G.J. Todd, A. Benvenisty, J.F. McKinsey, N. Morrissey, R. Nowygrod, H. Malone, I.S. Kotchetkov, and E.S. Connolly. 20. NGAL as a marker of hepato-renal syndrome. A. Young, M. Minhaz, and G. Wagener. 21. Medicare Reimbursement for Critically Ill Patients. R. Addante and H. Wunsch.

22. Preferences for autonomy and physician involvement in medical decision-making and correlation with level of patient distress in the chronic pain population. E. Rema, E. Garvin, and L. Mathew. 23. 2-Chloroprocaine is a safe and effective local anesthetic when used for spinal anesthesia. E. Garvin, A. Ho, and A. Dizdarevic.

CASE REPORTS 24. The Hanging Leg Technique: A New Approach to the Popliteal Block. A. Sieradzan and R. Brown. 25. A Case of Recurring Conversion Disorder Following Peripheral Nerve Block. C. Marshall and A. Dizdarevic. 26. Brachial Plexus Phenol Neurolysis for Metastatic Axillary Adenocarcinoma. M. Patel, D. Bandola, and A. Dizdarevic. 27. Oral Ketamine for the Treatment of Complex Regional Pain Syndrome Type II: A Case Report. N. Sekhri and M. Weinberger. 28. “I Dare to Hope”: Case Report of a Pain and Spirituality Group. J. Conrath, L. Golding, and N. Sonty. 29. Epidural Anesthesia for Labor and Cesarean Delivery in a Patient with Spondylothoracic Dysostosis. E. Harker and S. Goodman. 30. Pheochromocytoma Management during Cesarean Section. M. Monteleone and E. Reitman. 31. Cesarean Delivery in a Patient with Uncorrected Aortic Coarctation. J. Davila and S. Goodman. 32. Massive transfusion for orthotopic liver transplant in a pediatric patient. E. Greenidge and N. Saraiya. 33. Surgical Emergency requiring Massive Transfusion in patient with Tuberous Sclerosis. T.A. Chambers and S. Lei. 34. Fatal Left Ventricular and Aortic Thrombosis during Open Abdominal Aortic Debranching. L.M. Haselkorn and S. Miller 35. Anesthetic management of two children undergoing cardiac surgery with suspected mitochondrial disease. S. Mukkamala, T. Pinyavat, and C. Ing. 36. Anesthetic Considerations in a Patient Receiving a Transplanted Heart Procured from a Donor Exposed to Carbon Monoxide. J.R. Rentz, R. Kazim, and J. Chen. 37. Methylene Blue for Vasoplegia on Cardiopulmonary Bypass for Double-Lung Transplantation. M. Carley and J. Poppers.

38. Pentobarbital Withdrawal and Treatment in an Infant in the Pediatric Cardiac Intensive Care Unit. G. Weber, A.J. Smerling, and J.M. Saroyan. 39. Real time intracardiac and intravenous pressure monitoring to discover the location of superior vena caval obstruction. E.Y. Teo and J. Rumley. 40. “Pulling the Plug?”: Elective Withdrawal of Total Artificial Heart. D. Chmielewski and C. Blinderman.

College of Physicians and Surgeons of Columbia University DEPARTMENT OF ANESTHESIOLOGY 14th Annual Academic Evening Wednesday, June 1st, 2011 Heart Center, Riverview Terrace Guest Judge: Philip D. Lumb, MBBS, FCCM Professor and Chair, Department of Anesthesiology, Keck School of Medicine, University of Southern California, Los Angeles CA

ORAL PRESENTATION FINALISTS A1. Commonly used anesthetic agents interfere with axon guidance via a GABAergic mechanism. C.D. Mintz, MD, PhD, D.L. Benson, PhD, and N.L. Harrison, PhD A2. Biventricular pacing optimization using left ventricular dP/dt max fails to maximize cardiac output in a swine model of acute right ventricular pressure overload. Alexander Rusanov, Santos E Cabreriza, Lauren N Bedrosian, Suzanne R Karl, Bin Cheng, Henry M Spotnitz.

B1. Oxytocin Receptor Genotype Is Predictive of the Duration of the First Stage of Labor. Elena Reitman MD., Richard Smiley MD., PhD, and Pamela Flood MD.

B2. Interleukin Unintentional dural puncture with Tuohy needle increases risk of chronic headache. Webb C, Weyker P, Zhang L, Stanley S, Demarco C, Coyle T and Flood P. C1. Determination of Brain Death on Veno-Arterial Extracorporeal Membrane Oxygenation in Adults. Lloyd Meeks, MD, Gebhard Wagener, MD, Sumeet Goswami, MD.

POSTER PRESENTATION FINALISTS A3. Isoflurane generates adenosine to protect against renal ischemia-reperfusion injury. Minjae Kim, MD, Mihwa Kim, BS, Sang Won Park, PhD and H. Thomas Lee, MD, PhD.

A4. Plasma membrane potential is critical in the calcium-independent regulation of airway smooth muscle responsiveness: a new rationale for therapeutically targeting membrane ion channels. Peter Yim, George Gallos, Matthew Siviski, Charles W Emala A5. Withdrawal from repeated morphine administration induces long-lasting hyperalgesia and increases the insertion of calcium-permeable AMPA glutamate receptors in spinal cord synapses. D. Cabañero, Y. Xia, A. Baker, S. Zhou,S.M. Carlton and J.A. Morón Concepción. B3. Classification of Perioperative Complications: An Outcome-Oriented Approach. Nanshi Sha, M.S. Guohua Li, M.D. Dr.P.H. , and Joanne Brady, M.P.H.

B4. The Surgical Procedure Assessment (SPA) Score as a Predictor of Long Term Survival. Shreyajit Kumar, Hugh Playford, Robert N. Sladen, Gebhard Wagener.

B5. Early allograft dysfunction after liver transplantation. Brian Raffel, BS; Andrew Young BS, Jean C. Emond, MD, Gebhard Wagener, MD.

POSTER PRESENTATIONS LABORATORY RESEARCH A6. Viral transfection of AMPA glutamate receptor mutants within the hippocampus regulates the rewarding properties of morphine. G.S. Portugal, Y. Xia, R. Neve, S.J. Russo, J. Liu, and J.A. Morón Concepcion.

A7. Tumor necrosis factor-α alters sEPSP characteristics in nucleus accumbens medium spiny neurons. MW Nason Jr and NL Harrison. A8. Alcohol induces Vamp2, but not Vamp1, gene expression in neurons via activation of heat shock factor 1 (HSF1). F.P. Varodayan; L. Pignataro; N.L. Harrison. A9. Propofol Augments Gene Expression in Cortical Neurons. S.C. Smith; L. Pignataro; N.L. Harrison.

CLINICAL RESEARCH B6. The MELD score after liver transplantation. Brian Raffel MD, Andrew Young, BS, Moury Minhaz BS, Jean Emond MD, Gebhard Wagener MD.

B7. Intra-operative Transfusion requirements of extended donor criteria allografts. Teresa A. Mulaikal MD; Jean C. Emond, MD; Gebhard Wagener MD.

B8. Demographic and Clinical Modifiers of Initial Labor Pain Scores in the EASE Cohort: A Secondary Analysis. William M. Jackson; David R. Gambling, MB BS, FRCPC and Pamela Flood, MD.

B9. Mathematical Modeling of the Pain During the First Stage of Labor After Epidural Catheter. Sekhri N, Jackson W, Gambling D, Shafer S, Flood P. B10. Validation of a bi-exponential model for labor progress in a cohort of mixed parity with quantification of the impact of cervical effacement and fetal station. Maria Quincy, Fadi Mirza, Chunhua Weng, Richard Smiley, Pamela Flood.

B11. New York Statewide Planning and Research Cooperative System for Investigating Method of Anesthesia. Raymond S Park, M.D., Caleb Ing, M.D., Mitchell F Berman, M.D., M.P.H. and Lena S Sun, M.D.

B12. Rhabdomyolysis: Review of Literature and Analysis of Prevalence and Fatality in Pediatric Inpatients. Shah C, Pinyavat T, Rosenberg H, Sun LS. B13. A comparison of regional and general anesthesia for gastoschisis repair in infants. Connie Chung, Na Eun Kim, Alexander Friend, Erica Silverstein, Robert Williams, Lena Sun.

B14. Complications Associated with Thoracic Epidurals in Children. S. Mukkamala, T. Pinyavat, and R. Kazim.

B15. Frequency of Acute Changes found on Head CTs of General Medical and Surgical ICU Patients. Rebecca M. Bauer, MD, MPH; Guohua Li, MD, PhD; Hannah Wunsch, MD, MSc.

B16. 3-Dimensional Reconstruction of Musculoskeletal Tissue using Flouroscopy and Ultrasonography. Steven Yap MD, Leena Mathew, MD. B17. Factors Associated with Prolonged Intubations in Multi-Level Spine Surgery. Laura C. Friedman, M.D., Zirka H. Anastasian, M.D., and Eric J. Heyer, M.D., Ph.D.

B18. Characterization of Pain in the Barth Syndrome Population. Damani Taylor, Joanne Brady MS, Guohua Li, MD DrPH, Nomita Sonty Ph.D, John M. Saroyan MD.

B19. Dispositional Traits Predict Problem Solving Ability in Chronic Pain Patients. Madeline Schwartz, PsyD, MSEd, Emily Wald, BS, Nanshi Sha, MS & Nomita Sonty, PhD.

B20. Orthopedic Surgery Residents and Fellows Knowledge of Regional Anesthesia – An Assessment with an Educational Intervention. Christie M. Sasso, M.D., Danielle B. Ludwin, M.D., Emily Niu, M.D., William B. Macaulay, M.D.

B21. Goals and Motivations of Anesthesiology Residency Applicants. B. Liao, M. Monteleone, B. Egan.

CASE REPORTS C2. Continuous TEE Monitoring in the Cardio-Thoracic ICU. Insung Chung, Robert Sladen. C3. Transversus abdominis plane (TAP) block for postoperative analgesia in two renal transplant patients. Farheen
 Mirza,
M.D., Anthony
 R.
Brown
 MBChB,
FFA
(SA).
 C4. Continuous peripheral nerve block in a patient receiving antithrombotic therapy: A medically challenging case. Connie Chung, Danielle B. Ludwin, A. Robin Brown. C5. Two Case Studies of Countertransference in Palliative Care: Implications for Clinical Practice. Madeline Schwartz, PsyD, MSEd, Craig Blinderman, MD, MA, Nomita Sonty, PhD, MP. C6. Hemicrania Continua responds to radiofrequency ablation of supraorbital nerve: A Case Report. Weyker P, Webb C, Sanchez M, Mathew L. C7. How much is too much? Spinal Cord Stimulation and Serotonin Syndrome. Kiran Patel MD, Anis Dizdarevic MD.

C8. Liver Transplantation for Hepatopulmonary Syndrome Secondary to Abernethy Malformation. Scott Lipson MD, Pediatric Anesthesiology Fellow, Leila Pang MD. C9. Takotsubo Cardiomyopathy and Resultant Cardiogenic Shock after Mitral Valve Repair. Adam S. Evans, MD, MBA, Daniel B. Sims, MD, Nir Uriel, MD, Ulrich P. Jorde, MD, Joseph Rumley, MD, Craig R. Smith, MD.

C10. Tricuspid Valve Replacement and Maze Procedure in a 71-year-old Patient with Ebstein’s Anomaly. S.C. Smith, M. Dickstein. C11. The anesthetic challenges of a patient with Pompe disease and Klippel-Feil syndrome undergoing bilateral lower extremity osteotomies. Susan Lei, MD, Scott Lipson, MD, Gracie Almeida-Chen, MD, MPH, and Susumu Ohkawa, MD.

C12. Intracranial Hemorrhage in a Child with a Ventricular Assist Device. Glenn Mann, Caleb Ing.

C13. Malignant hyperthermia in an 11-year-old girl presenting for tonsillectomy and adenoidectomy. Edward Requenez, M.D. and Radhika Dinavahi, M.D.

College of Physicians and Surgeons of Columbia University DEPARTMENT OF ANESTHESIOLOGY Thirteenth Annual Academic Evening Faculty Club ‐ P&S 4‐446 Wednesday, May 26th, 2010 Guest Judge: Neal Cohen, M.D., Vice Dean of Academic Affairs, University of California, San Francisco Oral Presentation Finalists 1. Isoflurane reduces acute kidney injury induced liver and intestine dysfunction via intestinal sphingosine kinase activation. Minjae Kim, MD, Sang Won Park, PhD, Mihwa Kim, BS, Connie Chung, MD, H. Thomas Lee, MD, PhD. 2. Paneth cell activation after acute kidney injury causes liver and intestine injury and systemic inflammation in mice. SW Park, M Kim, KM Brown, VD D’Agati and HT Lee. 3. Effect of atrial latency on optimization of paced atrioventricular delay during temporary biventricular pacing. Alexander Rusanov M.D., Daniel Y Wang M.D., Santos E Cabreriza, Lauren N Bedrosian B.A, Suzanne R Karl B.A., Marc E Richmond M.D., T. Alexander Quinn PhD., Bin Cheng PhD, Henry M. Spotnitz M.D. 4. Interleukin-6 increases in humans undergoing laparoscopic nephrectomy. Steven Yap MD, Sang Won Park PhD, Jaime Landman MD and H. Thomas Lee MD, PhD . Poster Presentation Finalists 5. Isoflurane attenuates inflammation induced by acute kidney injury in small intestine. Connie Chung, MD, Sang Won Park, PhD, and H. Thomas Lee, MD, PhD. 6. Acute kidney injury after liver transplantation – A review of 803 cases. Andrew Young, BA, Minhaz Moury, BS, HT Lee MD PhD, Gebhard Wagener, MD 7. Modeling the dynamic norm of intra-operative blood pressure using semiparametric quantile regression. Nanshi Sha, M.S., Eric J. Heyer, M.D., Ph.D., Mitchell Berman, M.D., Guohua Li, M.D. Dr.P.H. 8. Genetic Contribution to the Pain and Progress of Labor. Elena Reitman, MD, Pamela Flood, MD, Steven Shafer, MD 9. Alcohol and heat shock regulate synaptotagmin 1 (Syt1) expression in cortical neurons. F.P. Varodayan; L. Pignataro; N.L. Harrison. 10. Novel expression of a functional glycine channel that attenuates contraction in airway smooth muscle. Peter D. Yim M.D., George Gallos M.D, Dingbang Xu Ph.D., Sarah Zaidi M.D., Yi Zhang M.D., and Charles W. Emala M.D. Poster Presentations

11. Activation of endogenous GABAA channels attenuates airway smooth muscle calciummediated oscillations in muscle force. Peter Yim, M.D.,George Gallos, M.D., Yi Zhang, MD and Charles W. Emala, M.D. 12. Chloride cycle generates depolarization mediated smooth muscle contraction. Peter D Yim, M.D., George Gallos, M.D., Yi Zhang, M.D., and Charles W Emala, M.D. 13. Repeated morphine administration alters AMPA glutamate receptor trafficking in the mouse hippocampus. Yan Xia, Jie Liu, Nicole Bjorklund, Jose Morón-Concepcion. 14. Ethanol Activates the Heat Shock Pathway in Astrocytes. L. Pignataro; F.P. Varodayan; L.E. Tannenholz; N.L. Harrison.

15. Addressing childhood obesity: The diminishing requirement of hypothalamic leptin signaling in regulating energy homeostasis. Laurence E. Ring and Lori M. Zeltser 16. Vasopressin deficiency and vasodilatory state in hepatic failure. Stephen Yap, Moury Minhaz, Fallon Mattis, Jean C Emond, Donald Landry, Gebhard Wagener. 17. Urinary Neutrophil Gelatinase-associated Lipocalin (NGAL) urine creatinine ratios after liver transplantation. Stephen Yap MD, Moury Minhaz BS, Fallon Mattis MD, Mihwa Kim MS, HT Lee MD PhD, Gebhard Wagener MD. 18. Protein C activity after Liver Transplantation and Early Graft Dysfunction. Adriana Rodriguez MD, Geraldine Diaz, DO, Moury Minhaz BS, John Rentz MD, Robert N. Sladen, MD, Gebhard Wagener MD. 19. ICU Delirium and Antipsychotic Agents after Cardiac Surgery. Shahzad Shaefi, M.D., David Vawdrey, Ph.D, Adriana Rodriguez, Peter Shapiro, M.D. and Robert Sladen, M.D. 20. Trends and Ethnic Disparities in the Utilization of Carotid Procedures in the US between 1998 and 2007. Robert Fairchild, Ph.D.; Joanne Brady, S.M.; Guohua Li, M.D., Dr.P.H. Eric J. Heyer, M.D. Ph.D. 21. Orthostatic hypotension and chronic oral antihypertensive therapy in pre-operative patients. Bess M. Storch, B.S.; Zirka H. Anastasian, M.D.; Eric J. Heyer, M.D. Ph.D.

22. A Scoring System to Predict Unplanned Intubation in Patients Undergoing Major Surgical Procedures. May Hua, MD, Joanne Brady, SM, Margaret Wood, MD, Mahmoud ElTamer, MD, Guohua Li, MD, DrPH 23. Outcomes in the medical intensive care unit: A physician-extender/ attending paradigm works as well as the traditional housestaff model. Gershengorn H, Wahab R, Leaf D, Brodie D, Li G, Factor P, Wunsch H. 24. Reliability of the New York Statewide Planning and Research Cooperative System (SPARCS) for Investigating Method of Anesthesia. Raymond S Park, M.D., Caleb Ing, M.D., Allana Forde, M.P.H., Mitchell F Berman, M.D., M.P.H. and Lena S Sun, M.D. 25. Epidemiology of Primary Pulmonary Hypertension in the Pediatric Population. T Pinyavat, MD; C Ing, MD; A Forde, MPH; J Brady, MS; and L Sun, MD. 26. In Hospital Mortality of Children Down Syndrome. J. Wisotsky MD, M. Hache MD, A. Forde MPH, J. Brady MS, C. Ing MD, L. Sun MD.

27. Co-morbidities in Pediatric Down Syndrome Patients. A. Forde, J. Wisotsky, J. Brady, L. Sun, C. Ing. 28. A retrospective review of urine toxicology results in outpatient pediatric pain management. Miller-Saultz D, Afzal A, Chung W, Sullivan MA, Saroyan JM. 29. Acceptance predicts physical self-efficacy in outpatients with chronic pain. Traci Stein PhD, MPH, Nomita Sonty, PhD. 30. Labor Analgesia in a Cohort of Chinese Women. T.W. Welsh, M.G. Irwin, P.D. Flood. 31. Daily Distribution of Deliveries and Anesthesia Workload in Two Labor and Delivery (L&D) Suites at an Academic Medical Center. Josue Rivera BS, Richard Smiley MD, PhD, Vanessa E. HennigRoshong, Shelby H. Davies, Pamela Flood MD. 32. Propofol dosing in endoscopic retrogradecholangiopancreatography. Farooq A. Qureshi, MD, Mitchell F. Berman, MD, Vivek K. Moitra, MD. 33. The Impact of a Seminar on Resident Knowledge of Evidence-Based Medicine. May Hua, MD, Brian Egan, MD, MPH. 34. Evaluating the efficacy of a novel patient safety curriculum. C. Gay, D. Jones, B. Egan. 35. Abstract Withdrawn 36. How professionalism is learned during residency. Samantha Harvey, M.D. & Sandra Curry, M.D.

College of Physicians and Surgeons of Columbia University DEPARTMENT OF ANESTHESIOLOGY Twelfth Annual Academic Evening Faculty Club ‐ P&S 4‐446 Wednesday, May 27th, 2009 Guest Discussant: Ronald G. Pearl, MD, PhD Professor, Department of Anesthesia Chair, Department of Anesthesia Stanford University School of Medicine Abstracts Oral Presentation Finalist 1. Selective hypothalamic leptin receptor knockout in a murine model leads to severe obesity and early diabetes. Ring, L, Zeltser, L 2. Sphinganine 1-phosphate ameliorates both acute liver failure and acute kidney injury induced by hepatic ischemia and reperfusion in mice. Park, S, Chen, S, Kim, M, D'Agati, V, Lee, HT 3. MMP-9 activity before carotid endarterectomy is influenced by systemic inflammation and an MMP-9 promoter polymorphism. Gaudet J, Yocum T. Granat A, Lewis C, Heyer E 4, Three year mortality after intensive care for Medicare beneficiaries in the United States. Guerra C, Linde-Zwirble, W, Bamalo A, Angus D, Li G, Wunsch H Poster Presentation Finalists 5. Radiation exposure of the eye lens of the anesthesiologist compared to the neuroradiologist. Anastasian Z. Strozyk D, Gaudet J, Meyers P, Berman M 6 Epidemiology of Anesthesia-related complications in labor and delivery. Cheesman K, Brady J, .r::lood P, Li G. 7. Kidney-specific reconstitution of the A1 adenosine receptor in A1 adenosine knockout mice reduces renal ischemia·reperfusion injury. Kim M, C!Jen S, Park-S, Kim tvt D'Agati V, Lee HT 8. National estimates of anesthesia complications in major cardiac surgeries, 2001-5. Kuo C. Brady J., Li GUG 9. Infusion pump alarm limits created using historical data from an anesthesia EMR. Qureshi F, KheterpaJ S. Berman M 10. Urinary NGAL as a marker of renal injury comparing cadaveric with living related liver transplants. YapS, Minhaz M, Mattis F, Kim A1, Lee HT, Wagener G Poster Presentation 11. GABA transporters are expressed in human airway smooth muscle and epithelial cells. Zaidi S, Xu D, Emala C 12. Extended donor criteria liver transplants are at increased risk for postoperative acute kidney injury. Yap S, Minhaz M, Mattis F, Lee HT, Wagener G 13. Iatrogenic endobronchial hemorrhage requiring extracorporeal membrane oxygenation in a patient undergoing orthotopic liver transplantation. Hastie J, Kim M, Jones D

14. Mallampati scale as a predictor of airway injury in patients undergoing major surgical procedures. Hua M, Arunajadai S, Wood M, EI-Tamer M, Li G 15. Techniques for difficult peripheral venous access. Freudzon L, Gay C, Eagan B 16. Diuretics increase intraoperative pressor requirements for patients undergoing carotid endarterectomy. Anastasian Z, Gaudet J, Heyer E 17. Timing of post-operative stroke after surgical procedures. Anastasian Z, Bateman B, Linaris G, Berman M 18. The relationship between hypervigilance, distress, & optimism with chronic pain acceptance and disability. Tsui P, Sonty N 19. Multidisciplinary treatment of complex headaches in adolescence: a case study. Tsui P, Santy N, Saroyan,J 20. Use of methadone for pain management in an infant with junctional epidermolysis bullosa. Page C, Saroyan J. 21. A 9 year old girl with an undifferentiated somatoform disorder. Morcillo C, Wifliams D, Guthrie E, Landau, E,Saroyan J 22. A 13-year-old adolescent female with headaches. Churchiff J, Tresgallo M, Saroyan J 23. A prospective study of cognitive deficits, depression and PTSD in trauma patients without intracranial injury. Bauer R, Obremskey W, Abraham C, Anderson V, SongY, Archer K, Guiflamondegui O, Jackson J, Ely E 24. Elevated preoperative HbA1c in non-diabetic patients is associated with prolonged length of stay after cardiac surgery. Bauer R, Wagener G, Minhaz M, Gubitosa G, Sladen R, Moitra V 25. Impact of the Kimberly Clark rewarming system on temperature perturbations following cardiac surgery with cardiopulmonary bypass. Ju A, Rodriguez A, Arunjadai S, Playford H, Sladen R 26. High frequency oscillatory ventilation (HFOV) for respiratory acidosis in adult late-stage ARDS. Brand J, Yang D, Romano M, Wahlander S 27. Incidence of peri-anesthetic adverse events in children with congenital heart disease undergoing cardiac catherization. Moore R, Kakavou/i A, Carson M, Ohkawa S, Sun, L 28. Modulators of emergence agitation/delirium associated with sevoflurane anesthesia: a review of current literature. Yazdani A, Sun L 29. Adverse events related to anesthesia in children in surgical and non-surgical settings. Kakavou/i A, Carson M, Sobol J, Lin C, Ohkawa S, Galiza C, Li G, Sun L 30. Epidemiology of pediatric postoperative reported adverse events in anesthesia recovery areas. Kakavouli A, Carson M, Lin C, Silverstein E, Ohkawa S, Sun L

31. Procedure-and-patient-related risk factors for intraoperative respiratory adverse events in children. Kakavouli A, Cheruku S, Brady J, Ohkawa S, and Sun L 32. PEDS and PAED scales: PEDS scale differences better pain from emergence delirium. Kakavouli A, Galiza C, Lin C, Lo S, Carson M, Kubacki T, Saraiya N, Sun L 33. Sex differences in PACU opioid requirements in children following ENT surgery.lng C, Saroyan J, Haddad J, Gereau-Haddon S, Grunstein E, Kakavouli A, Sun L 34. Anesthesia for adjustable gastric banding (LABG) in 48 pediatric patients. Lopes M, Kubacki T, Zitsman J, Sun L. 35. Effect of self-reported ethnicity on the pain and progress during the first stage of nulliparous labor. Debtee, J, Connell-Price J, Evans-Smith J, Shafer S, Flood P. 36. Transfusion medicine and coagulation knowledge of anesthesiology residents: the role of a formal blood bank rotation. Sekhri N, Kim R, Padmanabhan A, Jones D, Schwartz J 37. Patient safety module questions. Gay C, Jones D

College of Physicians and Surgeons of Columbia University DEPARTMENT OF ANESTHESIOLOGY Eleventh Annual Academic Evening Faculty Club ‐ P&S 4‐446 Wednesday, May 28th, 2008 Guest Discussant: Jonathan Moss, MD, PhD Professor of Anesthesia and Critical Care Professor of the College The University of Chicago, IL Abstracts Basic Science 1. A novel pharmacologic strategy to potentiate relaxation of Human Airway Smooth Muscle. Gallos G, Zhang Y, Park SW, Sonnett JR, Yang J, Emala CW 2. Choline Treatment Reduces the Inflammatory Responsiveness of Macrophages. McKinstry A, Rowley TJ, Smith W, Flood P 3. The Role of Kv1.3 Potassium Channels in Lymphocyte Apoptosis. Mikami M, Kaku R, Kawakami, Yang J 4. Alpha-2 Adrenergic Agonists Protect Against Radiocontrast-Induced Nephropathy in Mice. Billings FT, Kim M, Chen SWC, Song JS, Lee HT 5. The Pacemaker HCN1 Channel is not Post-Transitionally Modified by SUMOylation. Kaku R, Mikami M, Kawakami T, Tibbs G, Yang J 6. Unique Post-Translational Modification of Erk5 Mitogen Activated Protein Kinase in the Kidneys. Kawakami T, Mikami M, Kaku R, Yang J 7. Mechanical Basis of Selective Inhibition of HCN1 Pacemaker Ion Channels by Propofol: Insights into Anesthetic Mechanisms and Novel Therapeutic Agents. Redd KJ, Lyaschenko AK, Yang J, Tibbs G 8. Sub-Millisecond, Camp-Sensitive Current Rectification in “Slow” HCN Pacemaker Channels: A Novel Mechanism for Shaping Neuronal Excitability. Lyashenko AK, Tibbs G 9. GABAa Agonist Relaxes Constricted Airways in Guinea Pigs In-Vivo Independent of Neural Contribution. Gleason NR, Zhang Y, Emala CW Clinical Science 10. Beta-2 Adrenoceptor Genotype and Progress in Term Active Labor. Daniel D, Miller R, Blouin JL, Emala C, Flood P, Smiley R. 11. Plasma Markers Associated with Cognitive Dysfunction in Patients Undergoing Carotid Endarterectomy. Gaudet JG, Teverbaugh L, Zurica J, Connolly ES, Heyer EJ

12. Minimum Intraoperative Mean Arterial Pressure is Associated with Postoperative Cognitive Performance in Older Hypersensitive Spine Surgery Patients. Gaudet JG, Yocum GT, Teverbaugh L, Quest DO, McCormick PC, Connolly ES, Heyer EJ 13. Risk Factors Inadequate Transthoracic Echocardiogram after Cardiac Surgery. Spellman J, Flynn BC, Wang S, Lam SW, Meltzer J, Moitra VK 14. Polymorphisms in the B2-Adrenergic Receptor are Associated with a More Rapid, Less Painful Labor. Evans J, Connel-Price J, Drosinos S, Jasper N, Randolph P, Flood P 15. Effects of Race on Reported Pain in Labor. Debiec JM, Connel-Price J, Evans J, Flood P 16. Nicotine Nasal Spray for Pain and Inflammation after Third Molar Surgery. Aflazi P, Yagoubian B, Akkara J, Alfi D, Connel-Price J, Yeh J, Eisig S, Flood P 17. A Revised Pediatric Emergence Delirium Scale for Infants and Children. Galiza C, Kakavouli A, Lo S, Sobol J, Lin S, Carson M, Saraiya N, Kubacki T, Sun L 18. Adverse Events Related to Anesthesia in Children in Surgical and Non-Surgical Settings. Kakavouli A, Carson M, Sobol J, Lin C, Ohkawa S, Schwartzenberger J, Galiza C, Li G, Sun L 19. Neonatal Hyperglycemia Following Cardiac Surgery Has No Impact on Morbidity or Mortality. Ing C, Boublik J, Kakavouli A, Lin C, Sun L 20. EEG Coherence Patterns during Isoflurane and Sevoflurane Anesthesia in Infants and Young Children. Lo SS, Grieve PG, Carson M, Sobol J, Emerson RG, Stark RI, Sun L 21. National Estimates of Anesthesia Complications in the United States 2005. Kuo C, Lang B, Li G 22. Anesthetic Considerations of Transcatheter Aortic Valve Implementation. Billings FT, Shanewise JS 23. Evaluation of an Automated Inferencing Engine Generation ICD-9CM Codes for Physician and Hospital Billing. Behta M, Friedman G, Manber M, Jordan D 24. Machine Learning: A Computer Can Categorize and Prioritize Free-Text Clinical Data. Jone JR, McKeown K 25. Digitally Assisted Heart Sound Monitoring Detects Changes in Heart Sounds During Induction. Daneshrand D, Jordan D, Schwartzenberger JC, Salgo P, Gainza C, Rose S, FitzJames I 26. Sex-Based Differences in Presence of Extra Heart Sounds during Induction and General Anesthesia. Daneshrand D, Jordan D, Fitz-James I, Salgo P, Rose S, Schwartzenberger JC 27. Comparison of the Allocation of Intensive Care Beds in England and the United States. Wunsch H, Harrison DA, Linde-Zwirble WT, Barnato AE, Rowan K, Angus DC Miscellaneous 28. Evaolutions of Ginny and Ernie’s Surgical Day: A Guide to Pediatric Anesthesia. Carson MP, Wood M, Kazim R, Sun L

29. Conversion from peripheral Nerve Stimulator to Ultrasound-Guided Regional Anesthesia. Clark M, Brown A 30. Identification and Treatment of Neuropathic Pain on Injured Adolescent. Reitman E, Saroyan J 31. The Clinical Uses of Dantrolene Appear to be Broader than We Think. Wei E, Sheth S, Jordan D 32. Diuretic Therapy for Pseudotumor Cerebri: Treating Head Pain by Ruining the Patient. Sheth S, Saroyan J 33. Cortical Control and Characterization of a Peripheral Nerve Bridge to Bypass Spinal Cord Injury. Haque RM, Winfree CJ, Campos L, Chakabarty S, Martin J

College of Physicians and Surgeons of Columbia University DEPARTMENT OF ANESTHESIOLOGY Tenth Annual Academic Evening Faculty Club ‐ P&S 4‐446 Wednesday, May 30h, 2007 Guest Discussant: Mark F. Newman, MD Merel H. Hamel Professor and Chairman Department of Anesthesiology Duke University Medical Center Durham, North Carolina Abstracts LABORATORY INVESTIGATIONS 1. Pre-exposure to vasopressin potentiates the vasoconstrictive effect of epinephrine in late anaphylaxis. Dewachter P, Emala, C.W 2. Isoflurane protects against renal ischemia-reperfusion injury via sphingosine kinase. Kim MH, Kim, M, Emafa, CW. Lee, H. T 3. Propofol attenuates acetylcholine-induced airway constriction after capsaicin pretreatment in guinea pigs in vivo. Gleason NR Zhang Y., Emala, C.W. 4. Chronic systemic choline is analgesic in a mouse model of postoperative pain. Greenidge E., Rowley, T., Flood P 5. The anti-apoptotic effect of B-adrenoreceptor blockers is mediated by both mitochondrial stabilization and a direct inhibition of caspase 9. Mikami M, Goubaeva, F., Yang, J 6. Dexmedetomidine protects against radiocontrast induced nephropathy in mice. Billings F. T. Kim, M, Kim, MH, Wang, S., Lee H. T 7. Coupling of tachykinin receptors to kinase and calcium pathways in human airway smooth muscle cells. Mizuta. K. Mizuta F., Xu D., Yang, J, Emafa, CW 8. Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol mediated relaxation. Gaffos G. Zhang, Y. Emafa,. C.W 9. Endogenous A1 adenosine receptors protect against hepatic ischemia reperfusion injury in mice. Kim J, Kim, M, Kim, MH, Gubitosa, G., Lee, H. T 10. GABAA receptors inhibit increases in intracellular calcium in human airway smooth muscle cells. Mizuta K. Yang, J, Zhang, Y., Emala. C. W 11. Sub-millisecond, camp-sensitive current rectification in "slow" HCN pacemaker channels: a novel mechanism for shaping neuronal excitability. Lyashchenko AK Tibbs, G.R. 12. Mechanistic basis of selective inhibition of HCN1 pacemaker ion channels by propofol: Insights into anesthetic mechanisms and novel therapeutic agents. Redd.K.J., Lyashchenko.AK., Yang, J, Tibbs. G.

CLINICAL INVESTIGATIONS 13. Development and validation of a dynamic model for predicting pain scores during the first stage of labor. Evans. J. Cornell-Price, J., Hong. D., Shafer. S, Flood. p_ 14. Superior outcomes for heart transplantation in pediatric patients with restrictive cardiomyopathy. Boqrad AJ. Chen, J.M, Mital S., Mosca. R.. Quaegebeur, J.M. Schwarzenberger, J.C. 15. Nicotine patch for postoperative pain. Hong B.D. Flood, P. 16. International variations in critical care services. Wunsch. H. Angus, D.C., Harrison, D.A, Collange, O., Fowler. R., Haste E., deKeizer, N.F., Kersten, A, Linde-Zwirble, W T, Sandiumenge, A, Sladen, R.N, Rowan.,K.M 17. Management of life-threatening respiratory failure in the ICU. Gaffnev A Wahlander. S. 18. Predicators of disability in patients with chronic pain. Katz W Sonty, N. 19. Differences in complications between onsite and offsite locations in children having anesthesia. Kakavouli A Gafiza, C., Sobol, J., Ohkawa $., Carson, M, Sun, L 20. Validation of the pediatric emergence delirium scale. Ga/iza C. Lin, C. E., Sobol, JB,. Lo. S., Carson, M.P., Sun, LS CASE REPORTS 21. Use of a standoff device to improve ultrasound imaging for regional anesthesia. Abrahams MS Wei/kens. E.P., Brown AR. 22. Sunblock in the ICU. lvascu N.. Moitra,V 23. Anesthetic management and results of the double switch operation for congenitally corrected transposition of the great arteries. Schultz T. Schecter. W, Mosca. R., Chen, J.M, Schwarzenberger, J. C. 24. Anesthetic management for a percutaneous pulmonary valve replacement (PPVR) in a 16year-old patient with insufficiency of a valved right ventricle-pulmonary artery conduit. Bezdikian V. Torres. A, Hellenbrand, B., Schwarzenberger, J C. 25. Methylene blue and vasodilatory shock. Flynn B. S!aden, R.N. 26. The loss of swallowing ability and gag reflex following the administration of intrathecal fentanyl. Moore R. Smiley, R. 27. Assessment of perioperative anesthetic risks and management of parental expectations in Duchenne's muscular dystrophy. Rastogi M Wu,O., Hrdlicka. V., Saraiya, N., Fitz-James, J. 28. Respiratory failure requiring extracorporeal membrane oxygenation in a 54 year-old man after discharge from coronary artery grafting. Doane M. Moitra, V.

29. Laparoscopic emergency appendectomy in a patient with trisomy 21, a fused cervical spine and Eisenmenger's syndrome. Seitz J, Fitz-James, J

College of Physicians and Surgeons of Columbia University DEPARTMENT OF ANESTHESIOLOGY Ninth Annual Academic Evening Faculty Club ‐ P&S 4‐446 Wednesday, May 31st, 2006 Guest Discussant: Doug Coursin, MD Professor of Anesthesiology and Internal Medicine University of Wisconsin Abstracts 1. Postoperative dexmedetomidine does not reduce the incidence of post-thoractomy neuralgia. Atchabahian A, Miller CC, Wahlander S 2. Delayed complete airway obstruction following the application of topical anesthesia to a pediatric patient – a loss of upper airway tone. Bilenker M, Jooste, EH 3. Experiential and Motivational factors influencing the choice of anesthesiology as a career. Caravajal L, Graham M, Curry S 4. The effect of nicotine on chronic pelvic pain. Cheng S, Flood P 5. Management of a child with long segment tracheal stenosis. Conley CM, Kazim R, Kubacki T, deSerres L, Mosca R, Sun L 6. Monocyte chemoattractant protein-1 elevations predict acute neurocognitive decline after carotid endarterectomy. Ducruet A, Mack WJ, Hickman ZL, Rassbach WM, Sisti A, Zurica J, Heyer EJ, Connolly, S. 7. Management of renal transplantation in pediatric patients with cardiac dysfunction. Ezrokhi M, Fitz-James, I 8. The case for peripheral nerve blocks in anticoagulated patients. Fanning RM, Patel P, Brown AR 9. Neurotransmitter and pharmacological control of pacemaker channel activation exerted by acidic lipids downstream of diacylglycerol kinase and phospholipase A2. Fogle KJ, Rozario AO, Lyashenko AK, Turbendian HK, Chaplan SR, Tibbs GR 10. Lidocaine infusion mediates protection against murine septic peritonitis via activation of G1 and P13kinase pathways. Gallos G, Lee HT 11. Beta-adrenergic receptor blockers inhibit neuronal apoptosis by interfering with both the intrinsic and the extrinsic apoptotic pathways. Goubaeva F, Yang J 12. Anesthetic management of scoliosis surgery in an adolescent with undiagnosed subclinical distal neuropathy interfering with neurophysiologic monitoring and neuromuscular blockade assessment. Hrdlicka V, Hache M 13. Enhanced delivery of anticancer drugs during cerebral hyperfusion. Wang M, Joshi S

14. Cognitive correlates of acceptance in a sample of chronic pain patients. Katz WA, Sonty N 15. The architecture of the selectivity filter of open HCN pacemaker channels is not coupled to the camp-sensing apparatus. Lyashenko AK, Fogle KJ, Dhilia A, Tibbs GR 16. The intravenous anesthetic propofol acts in a direct, membrane-delimited manner to inhibit HCN1 pacemaker channels. Lyashenko, AK, Yang J, Tibbs GR 17. Autistic adolescent on high dose propranolol for behavioral control presents for dental restorations. Lyubaskaya AS, Ezrohki M, Pang LM 18. GABAa receptors are expressed and facilitate relaxation on airway smooth muscle. Mizuta K, Osawa Y, Xu D, Zhang Y, Emala CW 19. Raf-1 mediates TNFα-induced sensitization of adenylyl cyclase in human airway smooth muscle cells. Osawa Y, Yim PD, Xu D. Emala CW 20. Functional expression of GABAa receptors in airway smooth muscle. Osawa Y, Xu D, Mizuta K, Emala CW 21. The surgical procedure assessment (SPA) score predicts ICU length of stay in cardiac surgical patients. Pazner O, Wunsch H, Playford H, Houstono J, Gubitosa B, Sladen RN, Wagener G 22. Survey of pediatric cardiac MRI practices from May 2004 to February 2006 at Children’s Hospital of New York (CHONY). Shaparin N, Schwartzenberger JS, Prakash A, Prince B 23. Delta and beta EEG power to increase following cardiopulmonary bypass in neonates. Sobol J, Lo SS, Carson MP, Corda R, Grieve PG, Stark RI, Sun L 24. Web-based epidemiological survey of complex regional pain syndrome. Sharma A, Agarwal S, Broatch JW, Raja SN 25. Hydrogen peroxide increases GABAergic mIPSC through presynaptic release of IP3 receptor sensitive calcium store in the spinal cord substantia gelatinosa neurons. Takahashi A, Mikami A, Yang J 26. Anesthetic management of giant intracranial and airway teratoma resection in a newborn. Villafone R, Fitz-James I 27. Arginine-Vasopressin decreases portal vein blood flow in liver transplantation. Wagener G, Kinkhabwala M, Renz JC, Gubitosa G, Birch M, Brentjens T, Brown R, Emond J 28. Increased urinary neutrophil-associated gelatinase lipocalin (NGAL) after cardiopulmonary bypass derived from kidneys. Wagener G, Borregaard N, Jan M, Sladen RN, Lee HT 29. Aprotinin increases urinary NGAL, a marker for renal tubular injury after cardiac surgery. Jalbout M, Gubitosa G, Wagener G, Sladen RN, Lee HT 30. Urinary neutrophil gelatinase-associated lipocalin (NGAL) correlates with change in serum creatinine after cardiac surgery. Wagener, G, Gubitosa G, Borregaard N, Bangert K, Sladen RN, Lee HT

31. Increased mortality associated with acute respiratory failure of extra-pulmonary origin. Wunsch H, Harrison DA, Young D, Bellingan G, Sladen RN, Rowan K