Cheryl L. Laffer, MD, PhD, FAHA Reference List Abstract Laffer CL, Laniado-Schwartzman M, Wang MH, Nasjletti A, Elijovich F. Cardiovascular extended abstracts. Compendium Series 2, 1011. 2003 Book Chapter Elijovich F, Laffer CL. Salt sensitivity. Hypertension Primer: the Essentials of High Blood Pressure: Basic Science, Popular Science and Clinical Management, 4th ed., Chapter 49, pp. 156-159, edited by Izzo, J. L., Sica, D. A., and Black, H. R. Philadelphia, Lippincott Williams & Wilkins 2008 Elijovich F, Laffer CL. Cushing's syndrome and human glucocorticoid hypertension. Comprehensive Hypertension, Chapter 69, pp. 835-864, edited by Lip, G. Y. H. and Hall, J. E. Philadelphia, MosbyElsevier 2007 Weinberg JW, Laffer CL. Adrenal vein sampling in the evaluation of hyperaldosteronism. Advances Therapy in Hypertension and Vascular Disease, Chapter 30, pp. 245-250, edited by Mohler, E. R. and Townsend, R. R. Hamilton, ON, Canada, B.C. Decker 2005 Dickinson M, Laffer CL, Elijovich F. The physiology of renal artery disease. Peripheral Vascular Disease: Basic Diagnostic and Therapeutic Approaches, Chapter 18, pp. 256-269, edited by Abela, G. S. Phila., Lippincott Williams & Wilkins 2004 Laffer CL, Elijovich F. Three angiotensin paradigms in one patient: etiology of hypertension, glomerular hemodynamics and long term glomerular protection. Methods in Molecular Medicine: Angiotensin Protocols, Chapter 2, pp. 23-37, edited by Wang, D. H. Totowa, Humana Press, Inc. 2001

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Book Chapter Elijovich F, Laffer CL. The role of telemedicine in the management of essential hypertension. Telemedicine-Practicing in the Information Age, Chapter 36, pp. 261-267, edited by Viegas, S. F. and Dunn, K. Phila.-N.Y., Lippincott-Raven Pub. 1998 Book C Laffer Shusterman. Potassium-resistant mutants and adaptation in Paramecium tetraurelia. University of Wisconsin. 1981 Papers Published Elijovich F, Laffer CL: Detrimental effects of dual ACEI-ARB Blockade: Is the prorenin receptor the culprit? Kidney International, in press 2011 2011 Laffer CL, Elijovich F: A critical appraisal of the clinical effectiveness of a fixed combination of valsartan, amlodipine and hydrochlorothiazide in achieving blood pressure goals. Integrated Blood Pressure Control 4:13335. 2011 Elijovich F, Laffer CL: Acute stroke: lower blood pressure looks better and better. Hypertension 56:808-810. 2010 Laffer CL, Elijovich F: Inflammation and therapy for hypertension. Curr Hypertens Rep. 12:233-242. 2010

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Papers Published Elijovich F, Laffer CL. A role for single-pill triple therapy in hypertension. Therapeutic Advances in Cardiovascular Disease 3, 231240. 2009 Elijovich F, Laffer CL. The relationship between CYP4A11 and human hypertension. J Hypertens. 26[8], 1712-1714. 2008 Laffer CL, Gainer JV, Waterman MR, Capdevila JH, LaniadoSchwartzman M, Nasjletti A, Brown NJ, Elijovich F. The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension. Hypertension 51[3], 767-772. 2008 Laffer CL, Bolterman RJ, Romero JC, Elijovich F. Effect of salt on isoprostanes in salt-sensitive essential hypertension. Hypertension 47 [3], 434-440. 2006 Elijovich F, Laffer CL. Masked hypertension: a clinical entity or statistical gymnastics? (Editorial). Clinical Autonomic Research 14[3], 140-142. 2004 Elijovich F, Laffer CL, Schiffrin EL, Gavras H, Amador E. Endothelinaldosterone interaction and proteinuria in low-renin hypertension. Journal of Hypertension 22[3], 573-582. 2004

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Papers Published Laffer CL, Laniado-Schwartzman M, Nasjletti A, Elijovich F. 20-HETE and circulating insulin in essential hypertension with obesity. Hypertension 43[2], 388-392. 2004 Laffer CL. Is sodium restriction important to hypertension? The argument for. J.Clin.Hypertens.(Greenwich.) 6[6], 335-337. 2004 Laffer CL, Laniado-Schwartzman M, Wang MH, Nasjletti A, Elijovich F. 20-HETE and furosemide induced natriuresis in salt-sensitive essential hypertension. Hypertension 41[3 Pt 2], 703-708. 2003 Laffer CL, Laniado-Schwartzman M, Wang MH, Nasjletti A, Elijovich F. Differential regulation of natriuresis by 20-hydroxyeicosatetraenoic Acid in human salt-sensitive versus salt-resistant hypertension. Circulation 107[4], 574-578. 2003 Elijovich F, Laffer CL. Participation of renal and circulating endothelin in salt-sensitive essential hypertension. Journal of Human Hypertension 16[7], 459-467. 2002 Laffer CL, Elijovich F. Essential hypertension of Caribbean Hispanics: sodium, renin, and response to therapy. J.Clin.Hypertens.(Greenwich.) 4[4], 266-273. 2002

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Papers Published Elijovich F, Laffer CL, Amador E, Gavras H, Bresnahan MR, Schiffrin EL. Regulation of plasma endothelin by salt in salt-sensitive hypertension. Circulation 103[2], 263-268. 2001 Baima J, Nicolaou M, Schwartz F, DeStefano AL, Manolis A, Gavras I, Laffer CL, Elijovich F, Farrer L, Baldwin CT, Gavras H. Evidence for linkage between essential hypertension and a putative locus on human chromosome 17. Hypertension 34[1], 4-7. 1999 Elijovich F, Laffer CL, Romero JC. Pathogenesis of essential hypertension: The kidney, slow pressor responses to angiotensin II and oxidative stress. BioMedicina 1, 303-309. 1998 Laffer CL, Amador E, Elijovich F. Significance of treating metabolic cardiovascular risk factors in New York Hispanics with essential hypertension. BioMedicina 1, 26-32. 1998 Elijovich F, Laffer CL, Schiffrin EL. The effects of atenolol and zofenopril on plasma atrial natriuretic peptide are due to their interactions with target organ damage of essential hypertensive patients. Journal of Human Hypertension 11[5], 313-319. 1997 Elijovich F, Zhao HW, Laffer CL, Du Y, DiPette DJ, Inagami T, Wang DH. Regulation of growth of the adrenal gland in DOC-salt hypertension. Role of angiotensin II receptor subtypes. Hypertension 29[1 Pt 2], 408-413. 1997

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Papers Published Kelleher JP, Elijovich F, Laffer CL, Padilla M. Cough induced by angiotensin-converting-enzyme inhibitors: Airway responses to inhalation of methacholine in patients who have essential hypertension. Mount Sinai Journal of Medicine 62[6], 445-452. 1995 Laffer CL, Elijovich F. Suboptimal outcome of management of metabolic cardiovascular risk factors in Hispanic patients with essential hypertension. Hypertension 26[6 Pt 2], 1079-1084. 1995 Laffer CL, Elijovich F. Predictors of the pressor response to the clinic visit in essential hypertensives with and without diabetes mellitus. Clinical Autonomic Research 4[6], 323-329. 1994 Elijovich F, Laffer CL. Bayesian analysis supports use of ambulatory blood pressure monitors for screening. Hypertension 19[2 Suppl], II268-II272. 1992 Elijovich F, Laffer CL. Magnitude, reproducibility, and components of the pressor response to the clinic. Hypertension 15[2 Suppl], I161I165. 1990 Jan LY, Barbel S, Timpe L, Laffer CL, Salkoff L, O'Farrell P, Jan YN. Studies of Shaker mutations affecting a K+ channel in Drosophila. Current Topics in Membranes and Transport 23, 67-77. 1985

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Papers Published Jan LY, Barbel S, Timpe L, Laffer CL, Salkoff L, O'Farrell P, Jan YN. Mutating a gene for a potassium channel by hybrid dysgenesis: an approach to the cloning of the Shaker locus in Drosophila. Cold Spring Harbor Symposia on Quantitative Biology 48 Pt 1, 233-245. 1983 Shusterman CL, Thiede EW, Kung C. K+-resistant mutants and "adaptation" in paramecium. Proceedings of the National Academy of Science USA 75, 5645-5649. 1979 Presentation/Abstract Amador E, Laffer CL, Schiffrin EL, Elijovich F. Effects of sodium deprivation on plasma endothelin and blood pressure of essential hypertensive patients. 17th Scientific Meeting of International Society of Hypertension, Amsterdam. Journal of Hypertension 16[Suppl. 2], S95. xxxx Elijovich F, Brown MD, Laffer CL, Lell J, Wallace DC, DiPette DJ. Mitochondrial genotype and essential hypertension in Caribbean Hispanics. Southern Section, American Federation for Clinical Research, New Orleans. Journal of Investigative Medicine 44, 67. xxxx Elijovich F, Laffer CL. Correlates of the pressor response to the clinic in hypertensives with and without diabetes. Department of Medicine's Research Day. Mount Sinai School of Medicine. New York, 1989. Mount Sinai Journal of Medicine 57, 54. 1990. xxxx Elijovich F, Laffer CL. Differential blood pressure reduction by calcium channel blockers and converting enzyme inhibitors in Caribbean Hispanics. 11th Scientific Meeting of IASH. Montreal, Canada. Hypertension 25, 1355. xxxx

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Presentation/Abstract Elijovich F, Laffer CL. Sodium, renin and antihypertensive treatment in Hispanics of Caribbean descent. 8th Annual Meeting of ASH. New York. American Journal of Hypertension 6, 122A. xxxx Elijovich F, Laffer CL. Sodium, renin and antihypertensive treatment in Hispanics of Caribbean descent. 10th Scientific Meeting of IASH. La Jolla, Ca. Hypertension 21, 531. xxxx Elijovich F, Laffer CL, Bresnahan MR, Schiffrin EL, Gavras H. Endothelin, aldosterone, and proteinuria in low-renin essential hypertension. 19th Scientific Meeting of the International Society of Hypertension. Prague. Journal of Hypertension 20[Suppl. 4], S264S265. xxxx Elijovich F, Laffer CL, Goldman M, Schiffrin EL. Left atrial emptying, LVH and plasma ANF of essential hypertensives. 5th Annual Meeting of ASH. New York. American Journal of Hypertension 3, 87A. xxxx Elijovich F, Laffer CL, Gavras H, Schiffrin EL. Sodium sensitivity of blood pressure in essential hypertensive patients: a role for endothelin. 52nd Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Philadelphia. Hypertension 32, 605. xxxx Elijovich F, Laffer CL, Schiffrin EL, Gavras H. Co-stimulation of endothelin and catecholamines by low sodium in salt-sensitive hypertensive patients. 13th Scientific Meeting of IASH. Buenos Aires, Argentina. Hypertension 33, 1075. xxxx

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Presentation/Abstract Elijovich F, Laffer CL, Schiffrin EL. Contrasting effects of beta blockade and converting enzyme inhibition on plasma ANP of essential hypertensives. 8th Scientific Meeting of IASH. San Juan, Puerto Rico. Hypertension 13, 506. xxxx Elijovich F, Laffer CL, Schiffrin EL. Plasma ANF of hypertensives is affected differently by atenolol and zofenopril. 4th Annual Meeting of ASH. New York. American Journal of Hypertension 2, 73A. xxxx Laffer CL, Zhao H, Wang DH, DiPette DJ, Elijovich F. Role of AT1 and AT2 angiotensin receptors in organ hypertrophy in DOC-salt rats. 12th Scientific Meeting of IASH. Mexico City, Mexico. Hypertension 29, 841. xxxx Laffer CL, Bolterman R, Romero JC, Elijovich F. Isoprostanes in saltsensitive essential hypertension. 56th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Orlando, Fl. Hypertension 40, 391. xxxx Laffer CL, Elijovich F. Correlates of the white coat phenomenon in hypertensives with diabetes. 5th Annual Meeting of ASH. New York. American Journal of Hypertension 3, 45A. xxxx Laffer CL, Elijovich F. Bayesian analysis suggests that ambulatory blood pressure monitoring should be used as a screening tool for detection of hypertension. 9th Scientific Meeting of IASH. Rio de Janeiro. Hypertension 17, 441. xxxx

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Presentation/Abstract Laffer CL, Elijovich F. Ambulatory monitoring reveals two components in the pressor response to the medical visit. 4th Annual Meeting of ASH. New York. American Journal of Hypertension 2, 73A. xxxx Laffer CL, Elijovich F. Depressor responses to the visit identify essential hypertensives with greater target organ damage. Eight Annual Research Day. Mount Sinai School of Medicine, New York. Mount Sinai Journal of Medicine 57, 259. xxxx Laffer CL, Elijovich F. Essential hypertension in Caribbean Hispanics: sodium, renin and effects of therapy. 11th Annual Research Day, Mount Sinai School of Medicine. New York. Mount Sinai Journal of Medicine 60, 427. xxxx Laffer CL, Elijovich F. Inadequate management of cardiovascular risk factors in Caribbean Hispanic hypertensives. 11th Scientific Meeting of IASH. Montreal, Canada. Hypertension 25, 1386. xxxx Laffer CL, Elijovich F. The magnitude, reproducibility and components of the pressor response to the medical visit assessed by ambulatory monitoring. 8th Scientific Meeting of IASH. San Juan, Puerto Rico. Hypertension 13, 506. xxxx Laffer CL, Laniado-Schwartzman M, Nasjletti A, Elijovich F. 20-HETE and insulin resistance in obesity hypertension. 57th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Washington, DC. Hypertension 42, 421. xxxx

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Presentation/Abstract Laffer CL, Schwartzman M, Wang M, Nasjletti A, Elijovich F. 20-HETE in salt sensitive hypertension. 14th Scientific Meeting of IASH. Santiago, Chile. Hypertension 37, 1021. xxxx Laffer CL, Schiffrin EL, Gavras H, Elijovich F. Plasma endothelin of sibpairs: variability, inheritance, and linkage to obesity in essential hypertension. 54th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Washington, DC. Hypertension 36, 725. xxxx Laffer CL, Zhao HW, Schwartzman ML, Nasjletti A, Elijovich F. Urine 20-HETE in rat hypertension. 19th Annual Scientific Meeting of the American Society of Hypertension. New York. American Journal of Hypertension 17[pt.2], 140A. xxx Elijovich F, Laffer CL. Clinical and biochemical characteristics, and response to therapy in essential hypertensive Caribbean Hispanics. 10th Hispanic Medical Congress. San Antonio, Texas. 2222 Laffer CL, Laniado-Schwartzman M, Wang M, Nasjletti A, Elijovich F. 20-HETE and furosemide induced natriuresis in salt-sensitive hypertension. 56th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Orlando, Fl. Hypertension 40, 380. 2222 Laffer CL, Laniado-Schwartzman M, Wang M, Nasjletti A, Elijovich F. Urinary excretion of 20-HETE, natriuresis and salt-sensitivity of blood pressure in essential hypertension. 54th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Washington DC. Hypertension 36, 716. 2222

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Presentation/Abstract Laffer CL, Bolterman R, Romero JC, Elijovich F. Salt and oxidative stress in essential hypertension. 59th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Washington, DC. Hypertension 46, 2005. 2005 Laffer CL, Schiffrin EL, Gavras H, Elijovich F. Variability of plasma endothelin within a hypertensive sibpair is less than that between a group of sibpairs. 18th Scientific Meeting of the International Society of Hypertension. Chicago. Journal of Hypertension 18[Suppl. 4], S224. 2000 Elijovich F, Brown MD, Laffer CL, Lell J, Wallace DC. Native-American and African matrilineal gene pools and essential hypertension of Caribbean Hispanics. 16th Scientific Meeting of International Society of Hypertension, Glasgow. Journal of Hypertension 14[Suppl. 1], S30. 1996 Elijovich F, Zhao H, Laffer CL, Wang D, DiPette DJ. Differential effects of angiotensin II on organ growth in DOC-salt hypertension. 50th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research, Chicago. Hypertension 28, 536. 1996 Brown MD, Lell J, Elijovich F, Laffer CL, Wallace DC. Estimation of female genetic contribution to modern Caribbean populations using continent-specific mitochondrial DNA polymorphisms. American Journal of Human Genetics 57, 912. 1995 Elijovich F, Laffer CL, Schiffrin EL, Thornton JC. Volume-related clinical characteristics, not age or other correlates, explain plasma ANF of essential hypertensives in a multivariate model. 9th Scientific Meeting of IASH. Rio de Janeiro. Hypertension 17, 415. 1991

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Cheryl L. Laffer, MD, PhD, FAHA Reference List Presentation/Abstract Elijovich F, Laffer CL, Goldman M, Schiffrin EL. Plasma ANF of essential hypertensives reflects left atrial emptying, not LVH. 13th Scientific Meeting of ISH. Montreal. Journal of Hypertension 8[Suppl. 3], S48. 1990 Report Nauck MA, Meininger G, Sheng D, Terranella L, Stein PP, Laffer CL. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial. Diabetes Obes.Metab 9[2], 194205. 2006

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