Carmen Sandi - Publication list (2009-2014) For a comprehensive list of publications, see http://lgc.epfl.ch/page-34656-en.html

Peer-reviewed Research Articles van der Kooij M.A., Fantin M., Rejmak E., Grosse J., Zanoletti O., Fournier C., Ganguly K., Kalita K., Kaczmarek, and Sandi C.* (2014) Role for MMP-9 in stress-induced down-regulation of nectin-3 in hippocampal CA1 and associated behavioral alterations. Nature Communications 5:4995. doi: 10.1038/ncomms5995. Tzanoulinou S, Riccio O, de Boer MW, and Sandi C.* (2014) Peripubertal stress-induced behavioral changes are associated with altered expression of genes involved in excitation and inhibition in the amygdala. Translational Psychiatry 2014 Jul 8;4:e410. doi: 10.1038/tp.2014.54. van der Kooij M.A., Fantin M., Kraev I., Korshunova I., Grosse J., Zanoletti O., Guirado R., Garcia-Mompo C., Nacher J., Stewart M.G., Berezin V. and Sandi C.* (2014) Impaired hippocampal neuroligin-2 function by chronic stress or synthetic peptide treatment is linked to social deficits and increased aggression. Neuropsychopharmacology 39: 1148-1158. Poirier GL, Imamura N, Zanoletti O, and Sandi C. (2014) Social deficits induced by peripubertal stress in rats are reversed by resveratrol. Journal of Psychiatric Research 57: 157-164 Jedynak P, Kos T, Sandi C, Kaczmarek L, and Filipkowski RK. (2014) Mice with ablated adult brain neurogenesis are not impaired in antidepressant response to chronic fluoxetine. Journal of Psychiatric Research 56: 106-111. Tzanoulinou S, García-Mompó C, Castillo-Gómez E, Veenit V, Nacher J, and Sandi C.* (2014) Long-term behavioral programming induced by peripuberty stress in rats is accompanied by GABAergic-related alterations in the Amygdala. PLoS One 15;9(4):e94666. doi: 10.1371/journal.pone.0094666. Enriquez-Barreto L, Cuesto G, Dominguez-Iturza N, Gavilán E, Ruano D, Sandi C, FernándezRuiz A, Martín-Vázquez G, Herreras O, and Morales M. (2014) Learning improvement after PI3K activation correlates with de novo formation of functional small spines. Frontiers in Molecular Neuroscience 2;6:54. doi: 10.3389/fnmol.2013.00054. Veenit V., Riccio O. and Sandi C.* (2014) CRHR1 links peripuberty stress with social deficits and depression-like behaviors. Journal of Psychiatric Research 53: 1-7. Tzanoulinou S., Brandi R., Arisi I, D’Onofrio M., Urfer S.M., Sandi C.*, Constam D.* and Capsoni S.* (2014) Pathogen-free husbandry conditions alleviate behavioral deficits and neurodegeneration in AD10 anti-NGF mice. Journal of Alzheimer’s Disease 38: 951-964. Marquez C., Poirier G., Cordero M.I., Larsen M.H, Groner A., Marquis J., Magistretti P., Trono D. and Sandi C.* (2013) Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression. Translational Psychiatry 3: e216. doi: 10.1038/tp.2012.144. Kohl C, Riccio O, Grosse J, Zanoletti O, Fournier C, Klampfl SM, Schmidt MV, and Sandi C.* (2013) The interplay of conditional NCAM-knockout and chronic unpredictable stress leads to increased aggression in mice. Stress 16: 647-654. Cordero MI, Ansermet F, and Sandi C. (2013) Long-term programming of enhanced aggression by peripuberty stress in female rats. Psychoneuroendocrinology 38: 2758-2769. Poirier G.L.*, Cordero M.I. and Sandi C.* (2013) Female vulnerability to the development of depression-like behavior in a rat model of intimate partner violence is related to anxious temperament, coping responses and amygdala vasopressin receptor 1a expression. Frontiers in Behavioral Neuroscience, 7:35. doi: 10.3389/fnbeh.2013.00035.

Veenit V., Cordero M.I., Tzanoulinou S. and Sandi C.* (2013) Increased corticosterone in peripubertal rats leads to long-lasting alterations in social exploration and aggression. Frontiers in Behavioral Neuroscience 7:26. doi: 10.3389/fnbeh.2013.00026. Bisaz R., Boadas P., Genoux D. and Sandi C* (2013) Age-related cognitive impairments in mice with a conditional ablation of the neural cell adhesion molecule. Learning & Memory 20: 183193. Fantin M., van der Kooij M., Grosse Krummenacher C and Sandi C.* (2013) A key role for nectin1 in the ventral hippocampus in contextual fear memory. PloS One 8(2):e56897. Kohl C., Riccio O., Grosse J., Zanoletti O., Fournier C., Schmidt M.V.* and Sandi C.* (2013) Hippocampal neuroligin-2 overexpression leads to reduced aggression and inhibited novelty reactivity in rats. PloS One 8(2):e56871. Cordero M.I., Poirier G.L., Márquez C., Veenit V., Fontana X., Salehi B., Ansermet F. and Sandi C.* (2012) Evidence for biological roots in the transgenerational transmission of intimate partner violence. Translational Psychiatry 2:e106. doi: 10.1038/tp.2012.32. Knafo S., Venero C., Sánchez-Puelles C., Pereda-Peréz I., Franco A., Sandi C., Suárez l.M., Solís J. M., Alonso-Nanclares L., Martín E.D., Merino-Serrais P., Borcel E., Li S., Chen Y., Gonzalez-Soriano J., Berezin V., Bock E., DeFelipe J. and Esteban J.A. (2012) Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. PLoS Biology, 10(2):e1001262. Toledo-Rodriguez M., Pitiot A., Paus T. and Sandi C. (2012) Stress during puberty boosts metabolic activation associated with fear-extinction learning in hippocampus, basal amygdala and cingulate cortex. Neurobiology of Learning and Memory 98: 93-101. Castro J. E., Diessler S., Varea E., Márquez C.and Larsen M. H., Cordero M. I. and Sandi C.* (2012) Personality traits in rats predict vulnerability and resilience to developing stressinduced depression-like behaviors, HPA axis hyper-reactivity and brain changes in pERK1/2 activity. Psychoneuroendocrinology 37: 1209-1223. Bisaz R. and Sandi C.*. (2012) Vulnerability of conditional NCAM-deficient mice to develop stress-induced behavioral alterations. Stress 15: 195-206. Aberg K.C., Clarke A.M., Sandi C., and Herzog M.H. (2012) Trait anxiety and post-learning stress do not affect perceptual learning. Neurobiology of Learning and Memory 98: 246-253. Inostroza M., Cid E., Menendez de la Prida L. and Sandi C.* (2012) Different emotional disturbances in two experimental models of temporal lobe epilepsy in rats. PLoS One 7(6):e38959. Jedynak P., Jaholkowski P., Wozniak G., Sandi C., Kaczmarek L. and Filipkowski R.K. (2012) Lack of cyclin D2 impairing adult brain neurogenesis alters hippocampal-dependent behavioral tasks without reducing learning ability. Behavioral Brain Research 227: 159-166 Conboy L., Varea E., Castro J.E., Sakouhi-Ouertatani H., Calandra T., Lashuel H. and Sandi C.* (2011) Macrophage migration inhibitory factor (MIF) is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression and memory related behaviours. Molecular Psychiatry 16: 533-547. Timmer M., Cordero M.I., Sevelinge Y. and Sandi C.* (2011) Evidence for a role of oxytocin receptors in the long-term establishment of dominance hierarchies. Neuropsychopharmacology 36: 2349-2356. Kraev I., Henneberger C., Rossetti C., Conboy L., Kohler L.B., Fantin M., Jennings A., Venero C., Popov V., Rusakov D., Stewart M.G., Bock E., Berezin V. and Sandi C.* (2011) A peptide mimetic targeting of trans-homophilic NCAM binding sites promotes spatial learning and synaptic plasticity in the hippocampus. PloS One 6(8): e23433.

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Bisaz R., Schachner M. and Sandi C.* (2011) Causal evidence for the involvement of the neural cell adhesion molecule, NCAM, in chronic stress-induced cognitive impairments. Hippocampus 21: 56-71. Cuesto G., Enriquez-Barreto L., Carames C., Cantarero M., Gasull X., Sandi C., Ferrus A., Acebes A. and Morales M. (2011) PI3K activation controls synaptogenesis and spinogenesis in hippocampal neurons. Journal of Neuroscience 31: 2721-2733. Marroquin O., Cordero M.I., Setola V., Bianchi S., Galli C., Bouche N., Mlynarik V., Gruetter R., Sandi C., Bensadoun J.C., Molinari M. and Aebischer P. (2011) Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool. PloS One 6(4): e18268. Owczarek S., Soroka V., Kiryushko D., Larsen M.H., Yuan Q., Sandi C., Berezin V., Block E. (2011) Neuroplastin-65 and a mimetic peptide derived from its homophilic binding site modulate neuritogenesis and neuronal plasticity. Journal of Neurochemistry 117: 984-994. Toledo-Rodriguez M. and Sandi C. (2011) Stress during Adolescence Increases Novelty Seeking and Risk-Taking Behavior in Male and Female Rats. Frontiers in Behavioral Neuroscience 7;5:17. PMID: 21519389. Inostroza M., Cid E., Brotons-Mas J., Gal B., Uzcategui J.G., Sandi C. and Menendez de la Prida L. (2011) Hippocampal-dependent spatial memory is preserved in an experimental model of temporal lobe epilepsy in rats. PloS One, 6(7): e22372. Conboy L. and Sandi C* (2010) Stress at learning facilitates memory formation by regulating AMPA receptor trafficking through a glucocorticoid action. Neuropsychopharmacology 35: 674-685. Larsen M.H., Mikkelsen J.D., Hay-Schmidt A. and Sandi C.* (2010) Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment. Journal of Psychiatric Research, 44: 808-816. Bisaz R. and Sandi C.* (2010) The role of NCAM in auditory fear conditioning and its modulation by stress: A focus on the amygdala. Genes, Brain and Behavior 9: 353-364. Castro J., Varea E., Marquez C., Cordero M.I., Poirier G. and Sandi C.* (2010) Role of the amygdala in antidepressant effects on hippocampal cell proliferation and survival and on depression-like behavior in the rat. PloS One, 5: 5, e8618. Salehi B., Cordero M.I. and Sandi C.* (2010) Learning under stress: The inverted-U-shape function revisited, Learning & Memory 17: 522-530. Calandreau L., Márquez C., Bisaz R., Fantin M. and Sandi C.* (2010) Differential impact of polysialyltransferase ST8SiaII and ST8iaIV knockout on social interaction and aggression, Genes Brain & Behavior 9: 958-967. Timmer M. and Sandi C.* (2010) A role for glucocorticoids in the long-term establishment of a social hierarchy, Psychoneuroendocrinology 35: 1543-1552. Owczarek S., Kiryushko D., Larsen M.H., Kastrup J.S., Gajhede M., Sandi C., Berezin V., Bock E. and Soroka V. (2010) Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor, FASEB Journal 24:1139-50. Køhler L.B., Christensen C., Rossetti C., Fantin M., Sandi C., Bock E. and Berezin V. (2010) Dennexin peptides modeled after the homophilic binding sites of the neural cell adhesion molecule (NCAM) promote neuronal survival, modify cell adhesion and impair spatial learning, Eur. J. Cell Biol. 89: 817-827. Luksys G., Gerstner W., and Sandi C. (2009) Stress, genotype and norepinephrine in prediction of mouse behavior using reinforcement learning. Nature Neuroscience 12: 1180-1186.

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Zhou M., Conboy L., Sandi C., Joëls M., Krugers H.J. (2009) Fear conditioning enhances spontaneous AMPA receptor mediated synaptic transmission in mouse hippocampal CA1 area. European Journal of Neuroscience 30: 1559-1564. Luethi M, Meier B., and Sandi C. (2009) Stress effects on working memory, explicit memory, and implicit memory for neutral and emotional stimuli. Frontiers in Behavioral Neuroscience, DOI:10.3389/neuro 08.005.2008. Conboy L., Tanrikut C., Zoladz P.R., Campbell A.M., Park C.R., Gabriel C., Mocaer E., Sandi C. and Diamond D.M. (2009) The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats. International Journal of Neuropsychopharmacology 12: 329-341. Luksys G., Sandi C., and Gerstner W. (2009), Stress, noradrenaline, and realistic prediction of animal behaviour using reinforcement learning, Advances in Neural Information Processing Systems, 21: 1001-1008 (MIT Press).

Review Articles (peer-reviewed) Sandi C.* and Haller J. (2015) Stress and the Social Brain. Nature Reviews Neuroscience; Commanded article; in press. van der Kooij M.A. and Sandi C.* (2015) The genetics of social hierarchies. Current Opinion in Behavioral Sciences 2: 52-57. Haller J., Harold G. Sandi C., and Neumann I. (2014) Effects of adverse early-life events on aggression and anti-social behaviors in animals and humans. Journal of Neuroendocrinology. doi: 10.1111/jne.12182. Schumann G., Binder E., Holte A., de Kloet E.R., Oedegaard J., Robbins T.W., Walker-Tilley T.R., Brown V.J., Buitelaar J., Ciccocioppo R., Cools R., Escera C., Fleischhacker W., Flor H., Frith C.D., Heinz A., Johnsen E., Kirschbaum C., Klinberg T., Lesch K.P., Lewis S., Maier W., Mann K., Martinott J.L., Meyer-Lindenberg A., Müller C.P., Müller W.E., Nutt D.J., Persico A., Perugi G., Pessiglione M., Preuss U.W., Roiser J., Rossini P.M., Rybakowski J.K.,Sandi C., Stephan K.E., Undurraga J., Vieta E., van der Wee N., Wykes T., Haro J.M. and Wittchen H.U. (2014) Stratified medicine for mental disorders. European Neuropsychopharmacology 24: 5-50. Sandi C.* (2013) Stress and Cogntion. WIRES Cognitive Sci 4: 245-261. doi: 10.1002/wes.1222. van der Kooij M.A. and Sandi C.* (2012) Social Memories in Rodents: Methods, Mechanisms and Modulation by Stress. Neuroscience Biobehavioral Reviews 36: 1763-1772. Sandi C.* (2011) Glucocorticoids act on glutamatergic pathways to affect memory processes. Trends in Neuroscience 34: 165-176. Luksys G. and Sandi C.* (2011) Neural mechanisms and computations underlying stress effects on learning and memory. Current Opinion in Neurobiology 21: 502-508. Sandi C.* and Richter-Levin G.* (2009) From high anxiety trait to depression: A neurocognitive hypothesis, Trends in Neuroscience 32: 312-320. Bisaz R., Conboy L. and Sandi C.* (2009) Learning under stress: A role for the neural cell adhesion molecule NCAM. Neurobiology of Learning and Memory 91: 333-342.

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Commentary, Opinion Articles (invited) Sandi C.* (2011) Healing anxiety disorders with glucocorticoids. Proc. Natl. Acad. Sci. USA 108: 6343-6344. Sandi C.* (2011) Extending the impact of stress on hippocampal neurogenesis. European Journal of Neuroscience 33:1832.

Monographs Sandi C., Meyer-Lindenberg A. and Poirier G., Eds. (2010) Understanding Violence, Special Topic in Frontiers in Behavioral Neuroscience.

Book Chapters Luksys G. and Sandi C. (2014) Synaptic mechanisms and cognitive computations underlying stress effects on cognitive function. In: Stres at the Synapse. Synaptic stress and pathogenesis of neuropsychiatric disorders (M. Popoli, D. Diamond andG. Sanacora, eds.), Springer. Sandi C. (2011) Effects of Chronic Stress on Memory and Neuroplasticity: Animal Studies. In: Handbook of Stress: Neuropsychological Effects on the Brain (C. Conrad, ed.), Wiley Blackwell.

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