Brain Aging & Decline. Genetics Nutrition Free radicals Hormone dysfunction Stress Trauma Disease processes

Mental Clarity 1 Brain Aging & Decline Genetics Nutrition Free radicals Hormone dysfunction Stress Trauma Disease processes 2 All destroy neurons...
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Mental Clarity

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Brain Aging & Decline Genetics Nutrition Free radicals Hormone dysfunction Stress Trauma Disease processes 2

All destroy neurons

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DEGENERATIVE

BRAIN CHANGES 4

Healthy brain

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Degeneration

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Healthy circulation

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BRAIN AND

NERVE HERBS 8

General Nerve Herbs

General benefit for nerves Called “nervines” Sometimes called “Nerve Tonics” (Western herbalism use of term “tonic”)

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Nervine nerv·ine –adjective 1. of or pertaining to the nerves. 2. acting on or relieving disorders of the nerves; soothing the nerves. –noun 3 .a nervine medicine. [Origin: 1655–65; < NL nervīnus, equiv. to L nerv(us) nerve + -īnus -ine1 ] 10

Nervine

Nervines are not all relaxing

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Gotu kola

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Gotu kola Centella asiatica Cognitive and tissue healing Cold, bitter (Contradictory energetics, tonic, building herb) Ayurveda explains sweet “vipak” (tissue action)

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Superior nerve tonic

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Mandukaparni leaf (Gotu kola)

Karta Purkh Singh Khalsa Epilepsy & Migraine

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Karta Purkh Singh Khalsa Epilepsy & Migraine

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Tea

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Saag

Karta Purkh Singh Khalsa Epilepsy & Migraine

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Gotu Kola Pesto

Bacopa

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Bacopa

Colder, stronger brahmi (analog gotu kola)

Brahmi (Bacopa) (Bacopa monnieri) Improved word memory recall, distraction, attention, depression, anxiety scores, cognitive performance

(Journal of Alternative and Complementary Medicine, 2008)

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Shankapushpi flower

Karta Purkh Singh Khalsa Autism One

Photo credit Prashanti deJager 30

Shankapushpi herb Evolvulus alsinoides Warming, nervine, sedative, brain tonic Anxiety, insomnia, improving mental clarity, nervous debility, mental or emotional exhaustion, epilepsy

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Evolvulus alsinoides Characteristics- warming, nervine, sedative, brain tonic Uses- anxiety, insomnia, improving mental clarity, nervous debility, mental or emotional exhaustion, epilepsy

Karta Purkh Singh Khalsa Autism One

Photo credit Prashanti deJager 32

Shankapushpi

Mild relaxant Throughout day anxiety, or Bedtime for sleep Major herb in Ayurveda for epilepsy

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1-10 g per day, or as needed As decoction (tea), or capsules Karta Purkh Singh Khalsa Autism One

Photo credit Prashanti deJager 34

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Haritaki fruit

Haritaki

Ashwaganda root

Karta Purkh Singh Khalsa Epilepsy & Migraine

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Ashwaganda root

Root of “winter cherry” Grounding tonic Soup, gruel, capsules 15 grams short term building 1-2 grams lifelong

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Ashwaganda Fresh root

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Winter cherry Green fruit

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Karta Purkh Singh Khalsa Epilepsy & Migraine

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Calamus (Acorus)

Calamus

Acorus spp. (Western A. calamus, Chinese A. gramineus) Root

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Major herb for mind and brain Ayurveda Promotes awareness Increases brain circulation

Karta Purkh Singh Khalsa Epilepsy & Migraine

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Combined with gotu kola, which is cooling and mild —complementary benefits

Karta Purkh Singh Khalsa Epilepsy & Migraine

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Wild Vacha

Calamus (Acorus) Amarkantak Forest Karta Purkh Singh Khalsa Epilepsy & Migraine

Photo Prashanti47 deJager

Karta Purkh Singh Khalsa Epilepsy & Migraine

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Saraswati Churna Ayurvedic brain combination (ashwaganda, calamus, shankpushpi, ajwain, cumin, trikatu, rock salt) 2-6 g per day with honey & ghee

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MEMORY 50

Vitamin D

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Vitamin D

Outstanding for cognitive performance

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Vitamin D receptors widespread in brain tissue Vitamin D: neuroprotective effects including clearance of Alzheimer's Disease amyloid plaques Association: ↓ vit D, Alzheimer's disease/dementia Cognitive impairment 4x↑ severely deficient elders Association between ↓concentrations & cerebrovascular events (cerebrovascular accident, fatal stroke) 2 large prospective studies: low D ↑cognitive decline Vitamin D and cognitive function. Scand J Clin Lab Invest Suppl. 2012 Apr;243:79-82.

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Vitamin D in Mood Disorders Seasonal Affective Disorder more effective than light therapy

2004 Vitamin D3 enhances winter mood in healthy subjects

(Psychopharmacology)

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Most Americans 5,000-7,000 IU per day Get blood test

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Huperzia moss

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Huperzine A Extract Chinese club moss (Huperzia serrata) (Qian Ceng Ta) Alzheimer’s

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Huperzine A Powerful, highly selective for increasing acetylcholine in the brain

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Crosses blood/ brain barrier 50-400 mcg per day

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Precursor to serotonin

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Inositol

1-2 grams per day

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Ayurveda Herbs- Khalsa

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Choline

1-2 grams per day

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Phosphatidyl Choline

Superior form of choline Fat soluble

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Ayurveda Herbs- Khalsa

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BRAIN REMEDIES 69

Lithium Common mineral Use orotate form, not carbonate Prevents brain aging, damage, normal wear, shrinkage Antidepression Anorexia, cluster headache

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Lithium

Long history, many conditions Prevention brain aging and damage Extensive scientific literature supporting Cutting edge Substantial benefit brain diseases

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Lithium carbonate Bipolar disorder

Lithium orotate

Orotate form much less toxic

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Lithium

Very efficient delivery form Very low doses necessary Blood levels remain extremely safe (nondetetctable)

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Lithium

10-20 mg per day (from lithium orotate) 120-480 mg/day (total wt. lithium orotate)

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N-acetylcysteine (NAC) aka Acetylcysteine, N-acetyl-L-cysteine Derivative of cysteine acetyl group is attached to the nitrogen atom

Antioxidant and liver protecting effects Sulfate repletion in conditions, such as autism, where cysteine and related sulfur amino acids may be depleted

Oxidative stress 100 mg/kg body weight qd

Sulfur Main diet source sulfur amino acids Low sulfur associated with Parkinson's Alzheimer's

2.5% population Poor conversion cysteine to sulfate Poor detoxification Cell (neuron) damage

Healthy fats for the brain

Caution Coconut is cooling 79

Castor oil

Topical castor oil

Main treatment—nerve Pungent, sweet, heating Externally—analgesic, nervine Main treatment for cold, dry Standout—head, neck, brain

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Castor oil

Classic Asian nerve and brain remedy

External head massage shirodara Internal dose—bowel tolerance

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Castor plant

Ayurveda Herbs- Khalsa

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ALZHEIMER’S DISEASE 85

American elders with Alzheimer’s Disease 86

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Inflammation major factor

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Red & purple fruits

Vitamin E

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Vitamin E foods

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Mediterranean diet

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Alzheimer’s

Huperzine Calamus Omega-3 oils 93

Alzheimer’s Disease Prevalence

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Turmeric

Inflammation

Fresh turmeric

Antioxidant

Cellular immunity

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Curry

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Turmeric tea

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High dose

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Multiple sclerosis

Cholesterol

Platelet aggregation

Diabetes

Alzheimer’s

Nephrotoxocity

Chemotherapy

Antioxidant

Chemopreventive

Curcumin Antiangiogenic

Gallstone

Antiinflammatory

Cataract

Cardiotoxicity

Arthritis

Wound healing

Lung fibrosis

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Phosphatidylserine (PS) Natural phospholipid found in brain Studies, positive effects on neurotransmitters acetylcholine, serotonin, norepinephrine, dopamine

Improves behavior, cognitive function concentration, attention, memory

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Phosphatidylserine (PS)

Good evidence suggests PS helps declining mental function & depression in elderly Widely used Italy, Scandinavia, through Europe

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Phosphatidylserine (PS) Body makes all PS needs for daily life Therapeutic dosage much higher PS made from soybeans Dose (mental function) 100 mg 2-3 x/day Gradually reduce to 100 mg daily if effective

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ACETYLCHOLINE (Ach) Neuromodulator Neurotransmitter in peripheral nervous system & CNS Neuromuscular synapses Hippocampus Cerebellum Autonomic nervous system (ANS)

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Plasticity Arousal Reward Attention Memory 111

Excitatory synapses motor neurons & skeletal muscles inhibitory Vegas nerve GI tract Choline + acetic acid → Acetylcholine 112 112

Deficiency → Alzheimer’s

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Dietary Supplement 500-2,000 mg/day

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Choline

Acetylcholine

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Fat Soluble

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Reversible Acetylcholinesterase inhibitor

(Aricept) Increases cortical acetylcholine 118

Depression

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Chilies

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Gokshura seed

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Ayurvedic brain herb

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Mental clarity and depression

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Gokshura seed (fruit)

Tribulus terrestris Bai Ji Li 5 g per day, capsules

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Ginkgo leaf

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l-Phenylalanine

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l-phenylalanine Energy Depression 500-5,000 mg Not late

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l-Tyrosine

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Phenylalanine

Tyrosine 132

l-Tyrosine makes thyroxine

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Thyroxine = tyrosine + iodine

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Thyroxine = tyrosine + iodine

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l-tyrosine

Energy 500-3,000 mg Not late

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SAM-e (S-Adenosyl Methionine) 1600 mg per day

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Mental clarity is a lifelong project

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Join me for our first bonus class

Healthy skin 139