Borderline ventriculomegaly of fetal nervous system: diagnosis and management

Free communication 14: Ultrasound in perinatal medicine/ Borderline ventriculomegaly of fetal nervous system: diagnosis and management *Antonella Gian...
Author: Samuel May
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Free communication 14: Ultrasound in perinatal medicine/ Borderline ventriculomegaly of fetal nervous system: diagnosis and management *Antonella Giancotti, Antonella Spagnuolo, Gaia Pasquali, Valentina D'Ambrosio, Francescantonio Bisogni, Pierluigi Benedetti Panici Sapienza University Umberto I Hospital, Obstetrics and Gynecology, Rome, Italy Borderline ventriculomegaly is defined as a later ventricular diameter ≥10mm but ≤15mm. It occurs bilaterally in 0.15–0.7% of pregnancies and unilaterally in 0.07%. It is associated with an increased risk of chromosomal abnormalities, congenital anomalies, infections and childhood developmental delays. The aim of this study is to evaluate the management and the diagnostic approach of fetuses with mild cerebral ventriculomegaly. We followed 52 pregnancies with a fetal borderline ventriculomegaly from 19 to 36 weeks of gestations. All patients were submitted to TORCH complex screening, kariotype analysis, genetic and neurological counseling. A careful ultrasonographic surveillance with multiplaning software was performed until delivery. When other anomalies were suspected, magnetic resonance was required. All babies were submitted to ultrasound evaluation at birth and after three months. 10 patients underwent to magnetic resonance that confirmed the presence of associated cerebral anomalies. 34 fetuses had an unilateral ventriculomegaly (diameters range 9.8–12.8mm). This sign spontaneously regressed in 10 cases during gestation. In the other case newborns had a good Apgar score at birth and the transfuntanellar ultrasound examination showed mild isolated ventricular dilatation that disappeared at the third month of life. In the other 8 cases ventriculomegaly was bilateral. One of these patients presented CMV infections that determinate a fetal death. Isolated unilateral ventriculomegaly with diameters

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