BIOLOGY 388: PARASITOLOGY REVISED COURSE SYLLABUS: SPRING, 2014 INSTRUCTOR INFORMATION Dr. Susan Bandoni Muench Office: ISC 257 Phone: 245-5309 e-mail: [email protected] Office hours: Mondays, Wednesdays and Fridays, 1:30-2:20, Tuesdays 12:00-1:00 and by appointment.

COURSE DESCRIPTION In this course, we will examine parasites and parasitism, emphasizing the influence of parasites on the ecology and evolution of free-living species, and the role of parasites in global public health.

LEARNING OUTCOMES At the end of the course, students will be able to: 1. Differentiate among definitions of parasitism used by scientists with various disciplinary perspectives, and explain their choices among these definitions. 2. Demonstrate through quizzes, class activities and exams an understanding of the diversity of parasites and symbiotic associations, and the dynamic nature of symbioses. 3. Use scientific knowledge about parasites to interpret case studies and address real-life problems in Parasitology in class and during exams. 4. Explain the role of parasitism in the evolution of life on earth, and evaluate evidence for particular examples in class and on exams 5. Locate, read and evaluate literature to update knowledge of parasites and communicate the new information effectively in class discussion and in written assignments. 6. Select articles presenting new findings on a particular topic in Parasitology using the primary scientific literature, and present this knowledge to peers in a group oral presentation. 7. Demonstrate through class discussion and on take-home assignments and on tests an understanding of social and cultural attitudes to parasites and parasitism, and their influence on scientific research.

Accommodations for persons with disabilities: SUNY Geneseo will make reasonable accommodations for persons with documented physical, emotional or learning disabilities. Students should contact the Director in the Office of Disability Services (Tabitha Buggie-Hunt, 105D Erwin) and their faculty to discuss needed accommodations as early as possible in the semester.

REQUIRED TEXTS AND MATERIALS The text for this course is: Bogitsh, B. L., Carter, C. E. & Thomas Oeltmann. Human Parasitology. 4th edition. Burlington, MA: Elsevier Academic Press, 2012. Additional articles and case studies are available on MyCourses. You will need to bring copies (either electronic or paper) to class. You may need to print articles for the written assignments or print materials for some written assignments. In addition, you may wish to print lecture notes or other course materials. Please budget for these additional printing costs.

EVALUATION Tests (5) Final exam (2 parts) Reading quizzes, homework and class participation Writing assignments Laboratory (projects, quizzes, final practical) Total

200 200 100 100 200 800

ADDITIONAL INFORMATION ABOUT EVALUATION Reading quizzes and class participation: Reading quizzes are short quizzes covering the assigned readings and particular parasites for each class. Quizzes will be online, and may take place either inside or outside of class. Their role is to ensure that everyone has a common foundation of knowledge that will allow us to tackle more challenging and authentic problems in class. Your lowest 3 scores will be dropped. Class participation assignments will consist of individual or group work products from a class discussion activity. Class participation assignments will be graded as done well/done/not done. Lecture Tests: Short tests will take place in class. These tests may include multiple choice, short answer, and short essay components, and may be given online. Class activities and old exams will provide models of questions. Many questions are application problems that require you to use information learned through the reading and in class.

Exams: Two exams will be given during the final exam time slot. One exam will focus on specific parasites, and the other on parasitism and its ecological role and evolutionary impact. Both portions of the exam will include objective, short answer and essay components. Reflective assignment portfolio: A substantial portion of your grade will come from reflective writing assignments. These will require you to reflect on ideas from the course, and make connections to your other courses, career goals, and outside readings. Specific instructions (including specific topics and assignments) will be provided separately. Laboratory: The laboratory will be evaluated through quizzes, a final exam, and some presentations. Presentations will address particular parasites and diagnostic methods and issues. More information about these assignments will be provided separately.

Week

Topics and Readings

1 1/19-25

Mon.

Martin Luther King Day – no classes

Tues.

No laboratory the first week

Wed.

Introductions. What are parasites? Do Parasites Rule the World?

Mon.

Chapter 1 The Power of Parasites Microscope skills, tissues and samples Chapter 2 A Sleeping Storm Symbiotic Amebas: Entamoeba histolytica, E. dispar, E. hartmanni, E. coli, E. polecki, E. gingivalis, Iodamoeba butschlii, Endolimax nana, pp. 53-64 Fever without a Cause Worm Hunt Amebas

2 1/26-2/1

Tues. Wed. 3 2/2

Mon.

Tues. Wed.

Pathogenic free-living amebas: Naeleria fowleri, Acanthamoeba spp., Balamuthia spp., Microsporidians, Ciliates: Balantidium coli, pp. 6571. A Pig from Jersey

4 2/9

Mon.

Non-trichomonad flagellates: Giardia lamblia, Chilomastix mesnili, Retortamonis intestinalis, Enteromonas hominis, Dientamoeba fragilis, pp. 73-80 Beneficial parasites

Tues.

Flagellates QUIZ Trichomonads: Trichomonas tenax, T. vaginalis, Pentatrichomonas hominis, pp. 80-84

Wed.

5 2/16

Mon.

Tues. Wed.

6 2/23

Mon.

Tues.

7 3/2

Wed. Mon. Tues. Wed.

8 3/9

Mon. Tues. Wed.

Spring Break 9 3/23

No classes Mon. Tues. Wed.

Hemoflagellates: overview + Leishmania donovani, p. 85-98 Leishmania tropica, L. mexicana, L brasiliensis, P.98-101 Bullseye harmful mutualists Leishmanias & trypanosomes Trypanosoma brucei rhodisiense, T. brucei gambiense, pp. 101-108 Antigenic variation (review earlier reading and case study) Benefits of parasitism Trypanosoma cruzi, Sick on a South American Sugarcane Plantation Intruder in the Heart Writing assignment due Review and catching up, projects Coevolution and Evolution of Virulence Plasmodium vivax, P. ovale, P. malariae, P. falciparum, pp. 116-125 Attack and Counterattack Malaria QUIZ Additional aspects of malaria, pp. 125-135 Darwinian medicine and fever Babesia, Toxoplasma, pp. 137-148 Alteration of host behavior Other apicomplexans Reflective writing assignment due Cryptosporidium, Cyclospora, Isospora, Blastocystis hominis, 145-150 Alteration of host behavior

Liver flukes, pp. 179-187, Lung flukes, pp. 192-195 Why Bother? Evolution of sex Flukes PRESENTATIONS Intestinal flukes, 187-92

10 3/30

Mon.

Tues. Wed. 11 4/6

Mon. Tues. Wed.

12 4/13

Mon.

Tues. Wed. 13 4/20

Mon. Tues. Wed.

14 4/27

Mon. Tues. Wed.

15 5/4

Mon. Tues. Friday

Blood flukes, pp. 199-212 When A Sick Stomach Won’t Go Away The Therapeutic Helminth Flukes QUIZ Diphyllobothrium & sparganosis, pp. 237-240, pp. 252-254 Darwinian gastronomy Adult taeniid infections, pp. 241-249 Cospeciation GREAT Day – No lab Cysticercosis and hydatidosis (larval taeniid infections), pp. 254-265 Reflective writing assignment due Trichuris, Trichinella, pp. 291-301 Triumph by Treachery Sexually transmitted infections Tapeworms Hookworms, Strongyloides, pp. 301-313 Parasites & allergy Ascaris & Enterobius, pp. 314-319, 321-327 Sexual selection Nematodes QUIZ Zoonotic nematodes: Anisakis, Angiostrongylus, VLM, CLM pp. 313314, 319-320, 320-321, Wuchereria, Brugia, pp. 330-336 Parasite avoidance and the evolution of disgust Nematodes PRESENTATIONS Onchocerca, Loa and Guinea worm, 336-345 Wohlbachia Quiz and Lab Exam Final exams + reflective writing assignment due

Please note: Test dates are fixed, but topics and reading assignments are sometimes subject to change. Announcements will be made in class, and via email.

SOME IMPORTANT POLICIES Communication: Check your e-mail before each class in order to ensure that you receive information about any changes in the schedule. E-mail is also usually the fastest way to get in touch with me. Because I am working with hundreds of students this semester, please include your full name and the course name or number in all e-mails sent to me. Professionalism: Your active participation in class activities contributes not only to your own learning but also to the learning of others in the class. Please plan to arrive on time and stay throughout the class. Use laptops, cell phones and other technology only for class-related purposes during the lecture period. Due dates: Extensions are available but only with explanation and only when arranged in advance, except in the case of emergencies that arise on the due date. Class attendance: No points are awarded for attendance alone. However, class activities do not duplicate the reading, and it is not possible to make up reading quizzes. If you miss classes, make sure that you obtain copies of notes from other students. Handouts and graded work can be obtained in office hours. Academic dishonesty: Included in this category are cheating on exams and plagiarism. Both represent serious breaches of trust and will be treated accordingly. Either may result in a substantial grade reduction for that exam or project, and you may also be required to redo the exam or project under different conditions. The incident will be reported to the Dean of Students and the Dean of the College. Plagiarism is defined here as any form of misrepresentation of the authorship or originality of your work. Plagiarism includes (but is not limited to) copying others' work directly (including internet sources), paraphrasing minimally the work of others, presenting ideas without citing the original sources, turning in a paper written by someone else or turning in the same work in more than one course. Because academic dishonesty is defined in detail here, a claim of ignorance will not serve to excuse the behavior. Appealing grades: Any graded work may be submitted for re-evaluation along with a written appeal. The appeal must contain a brief written explanation of your concerns, including your understanding of the question or assignment directions and why you believe your work meets the requirements of the question or assignment. Ordinarily, this should occur within one week of when the work is returned to you.

Explanation of final grades: Grades are determined using the scale presented below usually without any adjustment or curve. Helping others can only help you, and cannot hurt your grade in any way. The point distribution is as follows: A (>93) B+ (87-89) B- (80-82) C (73-76) D (60-69) A- (90-93) B (83-86) C+ (77-79) C- (70-72) E (