ANSWERING TODAY’S QUESTIONS FOR TOMORROW’S WORLD

OUR MISSION To develop and share knowledge that improves the care of patients around the world through innovative clinical research.

2

DCRI AT A GLANCE OUR STRATEGIES FOR TODAY AND THE FUTURE At the DCRI, we:

We are committed to:

• Expand the impact of clinical research beyond drug approval • Design trials that shape the clinical standards of tomorrow • Translate the patterns of Big Data into actionable insights • Welcome the contribution of everyone to the story of better care for all • Activate the next generation of research forerunners

• Bringing the promise of personalized medicine to reality • Leading innovations in research design and operations • Supporting novel outcomes research and implementation • Moving quantitative science forward • Designing the educational platform of the future • Catalyzing global and community-based research

Trial Experience by Phase and Size: July 1, 2014–June 30, 2015 3%

Phase I

36

%

15%

Project Portfolio: July 1, 2014–June 30, 2015

49%

27%

Small ( 1–499 patients )

Phase II

Other/Registry

36.7%

Mega ( > 5,000 patients )

Government

6%

Large ( 2,000–4,999 patients )

30%

16

%

Phase III

63.3%

18%

Phase IV

Commercial

Medium ( 500–1,999 patients )

Manuscript Productivity 1081

1100 1000

949

900

More than 10,000 DCRI Publications

Publications

800 700

756 621

600 500

408

400 300 200 100 0

138 14

154 14

175 5

234

12

262

36

286

39

490

494

542

964

764

654

512

333

53

41

57

51

55

121

97

121

167

161

197

198

235

1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 High impact manuscripts published in journals with an impact factor greater than 10.0 (