Veterinary Oncology & Clinical Pathology
nantes CITÉ DES CONGRÈS,
FRANCE
October 20-22
2016 18th esVCp PROGRAM
ANNUAL CONGRESS
European Society of Veterinary Clinical Pathology
esVOnC ANNUAL CONGRESS
© Crédit photos : Fotolia
European Society of Veterinary ONCology
www.esvonc-esvcp-congress2016.com
Editorial
www.esvonc-esvcp-congress2016.com
Dear colleagues and friends, It is a great pleasure to welcome the first co-organized ESVCP and ESVONC congress in France, and for the first time in Nantes. Nantes is a beautiful port city, really easy to reach and very pleasant to live in. It is a city of culture and imagination with many architectural and art treasures. France is the country of gastronomy and good wines and Nantes is no exception. ESVCP and ESVONC scientific committees worked intensively to have a real co-organization with mixed sessions, in part focusing on oncology biomarkers and spontaneous animal models in clinical pathology and oncology. We hope that there will be a real interaction between clinical pathologists and oncologists as it really happens in practice. The meeting will be held between the 20 and the 22th of October 2016 at La Cité Nantes events center. The congress center is ideally located in the heart of the city and really easy to reach by public transport. A pre-congress day (19th of October) will also be organized as a continuing education program for veterinary clinical pathologists and oncologists. Apart from high quality invited speakers, free communications, clinical cases presentation and poster sessions will also be present. For the third year, a mystery slide session will also be organized. We really hope that you will enjoy this congress as much as we enjoyed organize it in a real spirit of cooperation.
www.esvonc-esvcp-congress2016.com
We are looking forward to seeing you in Nantes, Sincerely, Laetitia Jaillardon and Brigitte Siliart
Scientific Committee ESVCP Executive Committee Peter Graham, President Stefano Comazzi, Past President Stefan Neumann, Vice-President Kate English, Secretary Tim Williams, Treasurer Nazaré Pinto Da Cunha, Councillor Laetitia Jaillardon, Councillor
ESVONC Executive Committee
Organisation :
Frédérique Ponce, President Ana Lara Garcia, Vice-President Joachim Henriques, Secretary Tom Hendrickx, Treasurer Jérome Benoit Member at large
TMS Events Pôle d’activités de la Bretonnière CS 60025 85602 Montaigu, Cedex
Local Organizing Committee
Tél. : 00 33 (0)2 51 46 48 48 Fax : 00 33 (0)2 51 43 04 41
Laetitia Jaillardon Brigitte Siliart
©TMS Events - 27092016
Available on www.esvonc-esvcp-congress2016.com
PRE-CONGRESS DAY
- Nantes Events Center
09h00 09h45 10h30 11h00 11h45
WEDNESDAY, OCTOBER 19th ROOM I
MORNING: “ENDOCRINOLOGY SESSION” (09h00-12h30)
Can we trust our endocrine results ? Peter Graham Interpretation of endocrinology results: do not stop at the tip of the iceberg. Brigitte Siliart, Laetitia Jaillardon Coffee Break Is hyperthyroidism damaging to the feline kidney ? Tim Williams Endocrinology of the horse: from theory to practice. Brigitte Siliart, Laetitia Jaillardon
AFTERNOON : “DIAGNOSTIC SESSION” (14h00-17h30) 14h00 15h00 15h30 16h00 16h45 17h30
Omics and biomarker discovery: focus on tissue proteomics. Alessandro Tanca Application of proteomics to canine mammary tumors: looking for new biomarkers. Alessandro Tanca Coffee Break What’s new in flow cytometry for canine hematopoietic tumors? A clinical case approach. Stephano Comazzi Immunocytochemistry: a case-based approach. Nazare Pinto da Cunha End of the Pre-Congress
CONGRESS DAY - Nantes Events Center AUDITORIUM
THURSDAY, OCTOBER 20th
ROOM G H
REGISTRATION
07h45 08h50
Opening ceremony
09h00
Plenary lecture (Auditorium): Clinical research in veterinary oncology: the win-win challenge between clinical pathologists and oncologists Butty Villiers, Dick White Referrals, Cambridge UK David Berlato, Animal Health Trust, Newmarket UK
09h45
Plenary lecture (Auditorium): Delivering the future: personalized and molecularly derived-medicine Chand Khanna, Animal Clinical Investigation, Washington, US
10h30 11h00
COFFEE BREAK - EXHIBITION
Uncovering stress adaptation pathways as critical determines of the metastatic phenotype of osteosarcoma. Chand Khanna, Animal Clinical Investigation, Washington, US
ESVCP free communications : 11h00 - Reticulocytosis without anemia in dogs and cats, a multicenter study. Andreas Moritz, Germany 11h15 - Thrombotic risk assessment in Sprague-Dawley rats treated with different reference compounds. Martina Stirn, Germany 11h30 - Objective clinicopathological markers for predicting the outcome in dogs with chronic kidney disease (CKD): a retrospective study of 97 cases. Rania Baka, Greece
11h45
Canine tumors: a spontaneous animal model of human carcinogenesis Salomé Pinho, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP)
& i3S, Portugal
ESVCP and ESVONC free communications 11h45 - Investigation of the utility of fine needle aspiration cytology for the detection of lymph node metastasis in dogs. Quentin Fournier, UK 12h00 - Intestinal microbiota in lymphoma: a comparison in healthy dogs and dogs with non Hodgkin lymphoma. Jan Suchodolsky, Italy 12h15 - Multidrug resistance activity factor (MAF) calculations based on calcein test in canine lymphoma patients treated by various protocols. Valéria Dékay, Hungary
12h30
12h30-14h00 LUNCH BREAK - EXHIBITION
12h45
12h45-14h00 ECVCP committee meetings
AUDITORIUM 14h00
ROOM G H
Obesity session (14h00-17h00) 14h00 - Endocrinology of obesity: new insights for an old topic Michel Pugeat, Hospices Civiles de Lyon, Université Claude Bernard, Lyon, France
14h45
14h45 - Translational value of animal model of obesity- Thomas Lutz, Institute of Veterinary Physiology Vetsuisse Faculty-Centre of Integrative Human Physiology University of Zurich, Switzerland
ESVONC free communications (14h00-14h30) 14h00 - Anti-cancer activities of Salmonella Enterica serovar Agona in canine mammary gland tumour cells in vitro. Gayathri Thevi Selvarajah, Malaisia 14h15 - Increased anti-tumour effect of glutathione- stabilized gold nanoparticles conjugated to doxorubicin in vitro studies on canine osteosarcoma cell line. Anna Malek, Poland
ESVONC free communications 14h45 - Prospective evaluation of plasma and urine electrolytes as markers of response to L-Asparaginase in dogs with high-grade multicentric lymphoma: a proof of concept study. David Sayag, France 15h00 - c-kit prognostic value in feline invasive mammary carcinomas. Elie Dagher, France 15h15 - Preliminary results of serum thymidine kinase activity as a prognostic marker for prediction of relapse in dogs with multicentric lymphoma. Pierre Boyé, France
15h30
16h15
COFFEE BREAK - EXHIBITION
16h15 - Canine mammary carcinoma as a spontaneous model for obesity-associated breast cancer Laetitia Jaillardon, Oniris, Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering, Nantes, France
ESVCP free communications 16h15 - Canine nodal marginal zone lymphoma: descriptive insight into the biological behavior. Marzia Cozzi, Italy 16h30 - Comparison between wholes slide imaging and optical microscopy in the cytomorophological evaluation of canine lymphoma samples. Federico Bonsembiante, Italy 16h45 - Recommendations for clonality testing in the diagnosis of alimentary T-cell lymphomas in cats. Sabine E. Hammer, Austria
17h00
ESVONC AGM
18h00 19h30
Welcome reception and poster reception
ESVCP AGM
CONGRESS DAY - Nantes Events Center AUDITORIUM
FRIDAY, OCTOBER 21st
ROOM G H
REGISTRATION
08h30 09h00
Cancer circulating biomarkers session
CYTOLOGY SESSION
(09h00-11h45)
(09h00-10h30)
09h00
Minimal residual disease in human malignancies Jean-Yves Pierga, Institut Curie, Paris, France
Cytology of nervous system in Dogs and Cats David De Lorenzi, «I Portoni Rossi», Zola Predosa, Bologna, Italy
09h45
Circulating tumor cells (CTC) and mRNA tumor biomarkers in dogs Robert Klopfleish, Institute of Veterinary Pathology, Berlin University, Berlin, Germany
What is hiding there in the middle? Diagnostic approach of mediastinal masses in dogs and cats Francesco Cian, BattLab (Laboklin), Coventry, UK Roberta Rasotto, Dick White Referrals, Cambridge UK
10h30
11h00
COFFEE BREAK - EXHIBITION
Lymphopenia and blood ratio use in human malignancies as potential biomarkers Christine Menetrier-Caux, Centre Léon Bérard et Centre de Recherche en Cancérologie de Lyon, UMR INSERM-1052/CNRS-5286, France
ESVCP free communications Chairman: Jose Ceron 11h00 - Hematological and biochemical variations among Belgian Blue cattle and Holstein cows in Belgium. Eve Rameri, Belgium 11h15 - Haptoglobin concentration in cattle with chronic diseases. Elizabeth Schmidt, Brazil 11h30 - Serum protein concentrations in horses subjected to different exercise protocols. Elizabeth Schmidt, Brazil
11h45
Warburg effect in cancer. Hubert Lincet, UCBL1 - ISPB, Centre de Recherche en Cancérologie de Lyon UMR INSERM 1052-CNRS 5286, France
ESVCP free communications 11h45 - Monitoring performance of a point-of-care chemistry analyzer under field conditions in South Africa. Emma Hooijberg, South Africa 12h00 - Comparison of two methods (biuret and refractometry) for measurement of serum total protein in ruminants. Zoe Polizopoulou, Greece 12h15 - Validation of a new automated capillary electrophoresis assay for the measurement of major fraction of glycosylated hemoglobin (HbA1c) in dog: preliminary results. Ioannis Oikonomidis, Greece
12h30
LUNCH BREAK - EXHIBITION (12h30-14h00)
14h00
Plenary lecture (Auditorium): Onco-hematology - Chairman: Stefano Comazzi Critical evaluation of the reliability of cytology for the diagnosis of canine lymphoma: the European Canine Lymphoma Network results Eric Teske, Department Clinical Sciences of Companion Animals, Veterinary Faculty, University of Utrecht, Utrecht, The Netherlands
ECVCP AGM (12h30-14h00)
AUDITORIUM
14h45
Tox path session - Chairman: David Ledieu
ROOM G H
ESVONC free communications 14h45 - Cell-tube block: a new technique for studying neoplastic effusions in dogs and cats. Ricardo Marcos, Portugal
Role of preclinical safety assessment in cancer drug development Kuno Wuersch, Novartis, Basel, Switzerland.
15h00 - Retrospective evaluation of blood copper stable isotopes ratio 65cu/63cu as a biomarker of cancer in dogs. Gabriel Chamel, France 15h15 - Normal and malignant canine mammary epithelial cells shed exosomes in vitro with differentially expressed microRNA profiles by deep-sequencing analysis. Eric Fish, USA
15h30
Defining the value of comparative approach to cancer drug development Chand Khanna, Animal Clinical Investigation, Washington, US
-
16h15
Cytology of laboratory animals in biomedical research Florence Poitou, Charles River, Senneville, Canada
ESVONC free communications 16h30 - Prognostic significance of histopathology in canine anal sac gland adenocarcinomas: preliminary results in a retrospective study of 39 cases. Julie Pradel, UK 16h45 - Assessment of chemokine CCL2 in canine urogenital tumours and its potential as target for treatment. Naomi Shimizu, Belgium
18h00
SOCIAL EVENT
Evening
GALA DINNER
CONGRESS DAY - Nantes Events Center
AUDITORIUM
09h15 10h00
10h00 10h45
ROOM G H
08h30
SATURDAY, OCTOBER 22nd ROOM I
08h30 - 09h15 - REGISTRATION
LYMPHOMA SESSION (9h15-10h45) Genetic characterization of canine cancers and interest for targeted therapies : focus on lymphomas Benoit Hédan and Ronan Ulvé, Institut de Génétique et Développement de Rennes. UMR6290-CNRS, Université de Rennes 1, France Viral involvement in canine and human lymphoma Ruth Jarrett, MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland
Mystery slides session (9h15-10h45)
Carlo Masserdotti, Idexx Laboratory, Brescia, Italy
ESVCP free communications (10h00-10h45)
10h00 - Are oral, nasal and vulvar/ preputial samples the alternatives in detecting Leishmania infantum DNA? Ioannis Kavarnos, Greece 10h15 - Effect of subchronic exposure to zearalenone on hematologic and serum biochemical analytes in rabbits bucks. Theodora Tsouloufi, Greece 10h30 - Folatemia and cobalaminemia in healthy ferrets and in ferrets with gastrointestinal disorders. Daphné Rochel, France
AUDITORIUM
ROOM G H
COFFEE BREAK - EXHIBITION
10h45 11h15
ROOM I
ESVCP free communications
KIDNEY SESSION (11h15-12h45)
-
11h15 - Interest of anti-thyroglobulin antibodies assay at diagnosis of canine hypothyroidism: 155 cases. Nicolas Soetart, France
Diagnosing kidney disease, a better approach for earlier detection Jennifer Ogeer, Guelph University, Canada Sponsored by Idexx
11h30 - Growth hormone determination after thyrotropin releasing hormone stimulation to discriminate between primary hypothyroidism and non-thyroidal illness in dogs. Marrit M Prins, The Netherlands 11h45 - Mass spectrometry based method for measurement of canine insulin-like growth factor-I, -II and insulin-like growth factor binding protein-3. Emma Strage, Sweden
12h00
The complete urinalysis and an introduction to automated microscopy in veterinary medicine Jennifer Ogeer, Guelph University, Canada Sponsored by Idexx
12h45 14h15
Strengths and pitfalls with hematology analyzers in evaluation of cancer patients Inger Lilliehöök, University Animal Hospital, Uppsala, Sweden inger.
14h30 15h00 Monitoring side effects of Anti-tyrosine kinase in veterinary oncology. (15h00-15h45) Johan de Vos, Terneuzen, The Netherlands
15h45 What should appear on a pathology report of canine and feline mammary carcinomas: an overview of histopathologic data with prognostic and/or predictive impact. (15h45-16h30) Frédérique Nguyen, Oniris, Nantes-Atlantic, National College of Veterinary Medicine, Food Science and Engineering, Nantes, France 16h45
-
LUNCH BREAK - EXHIBITION
(14h15-15h00)
15h15
Biomarkers in saliva: general concepts Jose Joaquin Ceron, University of Murcia, Murcia, Spain
Quality session
(14h00-15h45)
The automation of guaranteed quality in human laboratory medicine. Henk Goldschmidt, Diagnostic Dutch Home Practitioners Service, Waalwijk, The Netherlands Banking of biospecimens for high quality biomarkers studies (14h30-15h15)
Fay Betsou, Integrated Biobank of Luxembourg, Luxemburg From quality management towards proper medical decisions in human laboratory medicine (15h15-15h45)
Henk Goldschmidt, Diagnostic Dutch Home, Practitioners Service, Waalwijk, The Netherlands
END OF THE CONGRESS
ESVCP/ESVONC case presentation (14h00-16h45) 1. Pancytopenia in a dog Eric Fish, USA 2. Skin nodules in a dog Chiara Piccinelli, Scotland 3. Orangutan with chronic respiratory problem Marilisa Novacco, Switzerland 4. Anemia in a jaguar Monika Keresztes, Germany 5 Sysmex scattergram in a cat Péter Vajdovich, Hungary 6. Spurious WBC scattergram and discrepancy in a dog Laetitia Piane, France 7. Pleural fluid in a dog Martina Piviani, UK 8. Anemia in a dog Liza Bau-Gaudreault, Canada 9. Blood smear from a dog Ioannis Oikonomidis, Greece 10. Laryngeal mass in a brachiocephalic dog Esther Torrent, Spain 11. Anemia in a lamb Harold Tvedten, Sweden