International Journal of Research in Medical Sciences Siddeswari R et al. Int J Res Med Sci. 2016 Apr;4(4):1035-1039 www.msjonline.org

pISSN 2320-6071 | eISSN 2320-6012 DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20160779

Research Article

HIV/AIDS-tuberculosis (pulmonary and extra pulmonary) co-infection: CD4 correlation R. Siddeswari1*, K. S. Amaravathi1, N. Srinivasa Rao1, Sanjeev2, B. Rewari3, Prabhu Kumar1 1

Department of Medicine, Osmania Medical College, Hyderabad, Telangana, India Medical Officer, 3Co-Ordinator, ART Centre, Osmania Medical College, Hyderabad, Telangana, India

2

Received: 20 October 2015 Revised: 18 January 2016 Accepted: 19 January 2016 *Correspondence: Dr. R. Siddeswari, E-mail: [email protected] Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Background: AIDS is the leading cause of death among people 15-59 years old in low income countries. Worldwide, approximately one-third of all AIDS-related deaths are associated with TB. TB is the primary cause of death for 1015% of patients with HIV infection. So the present study was conducted to find the correlation between sputum positivity and CD4 cell count in patients with HIV/AIDS-Tuberculosis co-infection. Methods: The present study was a retrospective hospital based study of patients with HIV/AIDS-Tuberculosis coinfection, attending ART centre, department of medicine, Osmania general hospital, Hyderabad, Telangana, India between November 2014 to September 2015. Data included clinical profile, complete blood picture, renal and liver function tests, sputum microscopy and C/S and chest X-Ray and others as and when required. Results: We included 180 HIV/AIDS infected patients on ART with tuberculosis (TB) co-infection. Out of 180 patients, 132 were males and 48 were females. Among male’s ≥40 (51.51%) year’s age group and among females 3039 (56.25%) year’s age group was the most commonly affected. Out of 180 cases 60 were sputum positive. 60 sputum negative pulmonary tuberculosis and 60 were extra pulmonary TB. CD4 cell count was 400/mm3 in 8 (13.3%) of sputum positive pulmonary TB, 4 (6.6%) of sputum negative pulmonary TB and 2 (3.3%) of extra pulmonary TB patients. Conclusions: Present study concludes that male sex and age group >30 years were the commonly affected population. All forms of tuberculosis were common when CD4 count was