•Recipes for 13 commonly used buffer solutions are included as standard Preparation recipes for commonly used buffer solutions are provided as standard. e.g. disodium phosphate, sodium acid citrate
•Instructions are shown on the display The target weighing value is shown on the display and analog bar in order to compare the target with the current weight. Manual calculation is not needed.
•Record function Record output with date, time and operator name.
pH level of mobile phase (eluent) solutions used in liquid chromatographs is adjusted to improve separation of components and extend the life of columns. This pH adjustment process is performed using a buffer solution. Currently, the most common method is using a pH meter to measure the pH as the solution is prepared; however, this process requires considerable time and effort, which can cause operational bottlenecks. An alternative method is available that does not require a pH meter. It involves preparing solutions by weighing fixed theoretically calculated quantities of an acid and base. AP series supports weighing these acids and bases. If the type and quantity of the buffer solution is specified, the balance displays the type and quantity of sample that should be weighed. Then the buffer solution can be prepared easily by adding water to the specified quantity of sample weighed accordingly.
Example of preparation by AP series Buffer solution preparation list
Number
Select the buffer solution mode.
Specify the type and quantity.
Displays the name and quantity of sample.
1
100mM
phosphoric acid (sodium)
pH = 2.1
2
10mM
phosphoric acid (sodium)
pH = 2.6
3
50mM
phosphoric acid (sodium)
pH = 2.8
4
100mM
phosphoric acid (sodium)
pH = 6.8
5
10mM
phosphoric acid (sodium)
pH = 6.9
6
20mM
citric acid (sodium)
pH = 3.1
7
20mM
citric acid (sodium)
pH = 4.6
8
10mM
tartaric acid (sodium)
pH = 2.9
9
10mM
tartaric acid (sodium)
pH = 4.2
10
20mM
acetic acid (ethanolamine)
pH = 9.6
11
100mM
acetic acid (sodium)
pH = 4.7
12
100mM
boric acid (potassium)
pH = 9.1
13
100mM
boric acid (sodium)
pH = 9.1
Prepare as instructed on screen.
Complete buffer solution
8
* Results can be printed with date/time and user ID.
S a m p l e P re parati on
(APW only)
Typically, preparation of a standard sample solution requires tedious calculations. AP series simplifies the process with automated calculations.
Example of preparation by AP series Weigh 25 mg Amitriptyline to make standard solution Standard sample of Amitriptyline is Amitriptyline Hydrochloride .
Standard solution of Amitriptyline
Calculation is essential to determine part of Acidum hydrochloricum by molecular weight to make 100 mg/mL Amitriptyline solution.
Amitriptyline 100 mg
Molecular weight of Amitriptyline: 277.4
1 mL
Molecular weight of Acidum hydrochloricum: 36.5 Molecular weight of Amitriptyline Hydrochloride: 277.4 + 36.5 = 313.9
Amitriptyline Hydrochloride
To compare the molecular weight of Amitriptyline Hydrochloride with Amitriptyline, the following calculation is necessary.
313.9/277.4 = 1.132 The molecular weight of Amitriptyline Hydrochloride is 1.132 times of Amitriptyline. So, if 25mg of Amitriptyline is used, it follows that the weight of Amitriptyline Hydrochloride should be: 25 mg × 1.132 = 28.3 mg. Hence, 28.3 mg of Amitriptyline Hydrochloride is needed to make the correct standard solution.
No need for manual calculation
AP series can automatically calculate the sampling weight using the molecular amount of the standard sample, molecular weight of unnecessary sample, and the target value in order to reach the correct concentration solution. Just weigh the target weight value on display and the target weight of the standard sample can be obtained.
Target weighing value Current sample value
"OK" mark shown when target weight is reached.
Standard sample value
Checking weighing conditions on the same display
AP Series
Advanced Performance UniBloc Balances
9
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(All models)
Operations can be kept secure with user ID and password protection. Access rights can be specified separately for each user to prohibit unauthorized actions such as performing calibration or changing the settings. User IDs can also be used for barcode management. User Selection Screen
Password Inputting Screen
P r i n t i n g D a t a i n A cco rd ance w i t h Var ious Regulat ions Functionality for customizing the content of printed information supports compliance with various ISO, GLP, GMP, and other requirements.
(All models) An example of printing Title of result Manufacturer name
Model name
• Date
Serial number
• Time
Date
• User name
Time
• Balance manufacturer name
User name
• User ID
Standard weight value
• Serial number
Weighing value before calibration
• Balance ID
Weighing value after calibration
• Software version • Minimum sample quantity
Signature
Example of selecting printed content
M i n i m u m S amp l e Q u an ti ty (War ning F unc t ion)
(All models)
Reproducibility can be confirmed by repeatedly measuring weights as instructed by AP series. The minimum sample quantity is automatically determined from the standard deviation and recorded in AP series. If the minimum sample quantity requirement is not satisfied during measurement, an indicator flashes to warn the user.
R e c i p e F u n c ti on Sample recipes can be registered, allowing users to simply follow instructions on display.
10
Minimum sample quantity
(AP-W only)
:\WWVY[PUN4VYL,MMPJPLU[3HIVYH[VY`>VYRHUK 7 Y V ] P K P U N / P N O L Y 9 L S P H I P S P [ ` Weighing results and analysis results can be stored in a database. Reports can be generated according to results in a prescribed format.
Analytical Balance
UHPLC
AP series
Nexera X2
Weighing results by Balance
Analysis results by LC
Database Analysis results by LC
LabSolutions software can store analysis results and weighing results in a database at the same time.
Weighing results by Balance
* When you use the LabSolutions software, you need the Balance Agent at the same time. If you have any questions about details, please feel like to contact us.
Report example
Analysis results by LC
Weighing results The report can be generated automatically according to results.
