African Journal of Biotechnology Vol. 10(45), pp. 9213-9217, 17 August, 2011 Available online at http://www.academicjournals.org/AJB DOI: 10.5897/AJB11.782 ISSN 1684–5315 © 2011 Academic Journals

Full Length Research Paper

Study of malondialdehyde (MDA) content, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities in chickens infected with avian infectious bronchitis virus Hai-feng Wang1,2, Xiu-hui Zhong1,3*, Wan-yu Shi1 and Bing Guo2 1

College of Animal Science and Technology, Agricultural University of Hebei, Baoding, 071001, China. 2 College of Animal Science and Technology, Hebei North University, Zhangjiakou, 075000, China. 3 Institute of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, China. Accepted 10 June, 2011

This study was carried out to investigate the changes of serum oxidative index in chickens infected with avian infectious bronchitis virus. Eighty (80) 15-day-old chickens were divided into two groups randomly: the control group and the experimental group. Birds in the experimental group were inoculated with infectious bronchitis virus, then the superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities and malondialdehyde (MDA) contents in the serum were detected in each group at days 1, 3, 6, 9, 12 post infection, respectively. Results showed that SOD and GSH-Px activities in the serum of the experiment group decreased after infection (P