A Guide to Inherited Breast and Ovarian Cancer Research and Services Dr Lisa Jeffers Macmillan Genetic Nurse Counsellor Northern Ireland Regional Genetics Service

Inheritance • The majority of breast/ovarian cancer is not due to an inherited condition, approximately 5-10% of breast cancer that occurs is due to an inherited predisposition (inherited breast cancer). • Two major genes associated with familial breast/ovarian cancer are the BRCA1 and BRCA2 genes (