Poster Presentations (102, 104/5, 107/8) (discussion 90 min) Odd numbers: September 27 (Tuesday) 15:30-17:00 Even numbers: September 28 (Wednesday) 16:10-17:40 Set up: September 27 (Tuesday) Removal: September 29 (Thursday) P-001

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Synthesis of O-glycopeptides using N,N'-isopropylidene dipeptide derivatives Hiroki Kobayashi1, Toshiyuki Inazu1 （ 1Tokai University, School of Engineering, Department of Applied Chemistry, 2Institute of Glycoscience, Tokai University） Synthesis and Biological Evaluation of Fluorescent Analogs of Polymyxin B Hiroyuki Suda1, Jin Nozaki1, Toshitada Yoshihara1, Keiko Komagoe2, Hiroyuki Oku1, Seiji Tobita1, Takashi Katsu2, Keiichi Yamada1 （1Gunma University, Graduate School of Engineering, Department of Chemistry and Chemical, 2Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences） SYNTHESIS AND CONFORMATIONAL ANALYSIS OF PEPTIDES COMPOSED OF CHIRAL FIVE-MEMBERED RING AMINO ACIDS Yoko Hirata1, Makoto Oba1, Makoto Fukudome1, Yosuke Demizu2, Masaaki Kurihara2, Mitsunobu Doi3, Masakazu Tanaka1 （1Graduate School of Biomedical Sciences, Nagasaki University, 2Division of Organic Chemistry, National Institute of Health Sciences, 3Osaka University of Pharmaceutical Sciences） DESIGN AND SYNTHESIS OF CONFORMATIONAL FREEDOM RESTRICTED ENDOMORPHINE-2 ANALOGUES Tomomi Hanada1, Takuma Kato1, Emi Ikeda1, Yosuke Demizu2, Masaaki Kurihara2, Mitsunobu Doi3, Yuko Tsuda4, Makoto Fukudome1, Makoto Oba1, Masakazu Tanaka1 （1Graduate School of Biomedical Sciences, Nagasaki University, 2National Institute of Health Sciences, 3Osaka University of Pharmaceutical Sciences, 4Faculty of Pharmaceutical Sciences, Kobe Gakuin University） SELENOCYSTEINE DERIVATIVES. SYNTHESIS AND APPLICATION TO SELENOPEPTIDE PREPARATION Michio Iwaoka, Yoshiko Urabe, Hiroyuki Kuraishi （ Tokai University, School of Science, Department of Chemistry） MOLECULAR SIMULATION OF SHORT PEPTIDES CONTAINING UNCOMMON AMINO ACID RESIDUES BY USING THE SAAP FORCE FIELD Kenichi Dedachi1, Takeshi Nomura1, Taku Shimosato1, Toshiya Minezaki2, Michio Iwaoka1 （ 1Tokai University, School of Science, Department of Chemisry, 2Tokai University, School of Science, Laboratory of General Education for Science and Technology） A NOVEL MODIFICATION METHOD OF PEPTIDES AND PROTEINS BY ANIONIC DODECABORATE CAGE IN WATER Yoshihide Hattori1, Yuko Katsuta2, Mari Mukumoto2, Kouki Uehara3, Youichirou Ohta3, Tomoyuki Asano3, Minoru Suzuki4, Shin-ichiro Masunaga4, Koji Ono4, Shinji Tanimori2, Mitsunori Kirihata2 （ 1Osaka Prefecture University, Research Organization for University-Community Collaborations, 2Osaka Prefecture University, Department of Bioscience and Informatics, Graduate School of Life and Environmental Sciences, 3Stella Pharma Co., 4Kyoto University Research Reactor Institute） ELUCIDATION OF THE PRODUCTION OF AMYLOID BETA PROTEIN BY NEW PEPTIDE DERIVATIVES Tomikazu Kawano1, Kousuke Ikeuchi2, Satoshi Ogawa2 （1Iwate Medical University, School of Pharmacy, 2Iwate University, Graduate School of Engineering）

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Synthetic study of the depsipeptides analogues of callipeltin B and its cytotoxicity Mari Kikuchi1, Yoshihisa Watanabe2, Masaki Tanaka2, Kenichi Akaji3, Hiroyuki Konno1 （1Yamagata University, Graduate School of Science and Technology, Department of Biochemical Engineering, 2Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Basic Geriatrics, 3Kyoto Pharmaceutical University, Department of Medicinal Chemistry） Antihypertensive Actions of the Tripeptide Gly-His-Gly Isolated from Fermented Buckwheat Sprout Masahiro Koyama1, Yukimi Hashiguchi2, Kozo Nakamura2 （1Department of Bioscience and Food Production Science, Interdisciplinary Graduate School of Science and Technology, Shinshu University, Nagano, Japan, 2Department of Bioscience and Biotechnology, Graduate School of Agriculture, Shinshu University, Nagano, Japan.） Processing of precursor protein of the cricket Gryllus bimaculatus circadian rhythm neuropeptide PDF and PAP and their axonal transport Miki Shimohigashi1, Marina Yonemura1, Takeshi Honda2, Hiroyuki Nakagawa1, Yasuyuki Shimohigashi3 （1Fukuoka University, Faculty of Science, Department of Earth System of Science, Division of Biology, 2Kyushu University, Faculty of Science, Department of Chemistry, 3Kyushu University, Faculty of Science, Department of Chemistry, and Risk Science Research Center） SYNTHESIS OF CYCLIC LIPOPEPTIDE DERIVATIVES OF BURKHOLDINES AND ITS ANTIGFUNGAL ACTIVITIY Hiroyuki Konno1, Yusuke Otsuki1, Kenta Matsuzaki1, Megumi Ikoma1, Kazuto Nosaka2 （1Yamagata University, Graduate School of Science and Technology, 2Hyogo College of Medicine, Department of Chemistry） Chemical synthesis of sublancin, a bacterial S-linked glycopeptide Hidekazu Katayama, Yuya Asahina, Hironobu Hojo （ Department of Applied Biochemistry, School of Engineering, Tokai University） SYNTHESIS OF GLYCOPEPTIDE CONTAINING 6-O-PHOSPHORYLATED MANNOSE FOR AN α-DYSTROGLYCAN/LAMININ INTERACTION STUDY Mamoru Mizuno1, Kenji Osumi1, Yuriko Hirose1, Hiroshi Manya2, Tamao Endo2 （1The Noguchi Institute,Laboratory of Glyco-organic Chemistry, 2Tokyo Metropolitan Institute of Gerontology, Molecular Glycobiology, Research Team for Mechanism of Aging） NEW LIQUID PHASE PEPTIDE SYNTHESIS “Molecular Hiving Technology” Hitoshi Abe1, Hideaki Suzuki2, Shuji Fujita2, Kazuo Nagano1, Toshihide Yamada1, Nobuyoshi Ebata 1, Kazuhiro Chiba3 （1Sekisui Medical Co., Ltd. Iwate Research and Development Center, 2JITSUBO Co., Ltd., 3Tokyo University of Agriculture and Technology, United Graduate School of Agriculture） DOUBLE-KINETICALLY CONTROLLED PROLINE LIGATION Hao Ding, Kohei Sato, Ko Morishita, Akira Shigenaga, Akira Otaka （Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima） FORMATION OF PEPTIDE THIOESTERS BY THE USE OF MODIFIED Cys-Pro ESTER (CPE) AUTOACTIVATING UNIT Akitaka Kamauchi, Emi Harada, Saburo Aimoto, Toru Kawakami （Osaka University, Institute for Protein Research） SYNTHESIS OF O-ACYL ISOPEPTIDE BY USE OF NATIVE CHEMICAL LIGATION TO EFFICIENTLY CONSTRUCT HYDROPHOBIC POLYPEPTIDE Youhei Sohma1, Hitomi Kitamura1, Hiroyuki Kawashima1, Hironobu Hojo2, Kenichi Akaji1, Yoshiaki Kiso3 （1Kyoto Pharmaceutical University, Department of Medicinal Chemistry, 2Tokai University, Department of Applied Biochemistry, 3Laboratory of Peptide Science, Nagahama Institute of Bio-Science and Technology） Practical Intramolecular Disulfide Formation Based On Hydrophobic Tag Strategy Shingo Kitada1, Shuji Fujita2, Yohei Okada1, Shokaku Kim1, Kazuhiro Chiba1 （1Tokyo University of Agriculture and Technology, Faculty of Agriculture, Department of Applied Life Science, 2JITSUBO Co. Ltd.）

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SYNTHETIC STUDY OF GLYCOYLATED IGV DOMAIN OF TIM-3 USING SEGMENT CONDENSATION METHOD Yuya Asahina1,2, Hidekazu Katayama3, Shigehiro Kamitori4, Hironobu Hojo1,2,3 （1Tokai University, Graduate School of Science and Technology, 2Tokai Universtiy, Institute of Glycoscience, 3Tokai University, Department Applied of Biochemistry, 4Kagawa University, Life Science Research Center） EFFICIENT SYNTHESIS OF FMOC-AMINOACYL-N-ETHYL-CYSTEINE, A KEY DEVICE FOR PEPTIDE THIOESTER PREPARATION Yuya Asahina1,2, Hajime Kobayashi3, Risa Ubagai3, Hidekazu Katayama3, Yuko Nakahara1,2,3, Yoshiaki Nakahara3, Hironobu Hojo3 （1Tokai University,Graduate School of Science and Technology, 2Tokai University, Institute of Glycoscience, 3Tokai University, Department of Applied Biochemistry） A NEW METHOD OF PROTEIN CROSS-LINKING FOR PREPARATION OF DEUBIQUITINATING ENZYME-RESISTANT UBIQUITIN DIMER Akihiko Oku1, Hao-Hsin Yu1, Ikuhiko Nakase1, Siroh Hutaki1 （1Institute for Chemical Research, Kyoto University, 2Graduate School of Pharmaceutical Science, Kyoto University） Design of Stapled Helical Peptides for Catalytic Enantioselective Epoxidation of alpha,beta-Unsaturated Ketones Yosuke Demizu1, Saori Nagoya1, Yukiko Sato1, Masakazu Tanaka2, Mitsunobu Doi3, Haruhiro Okuda1, Masaaki Kurihara1 （1National Institute of Health Sciences, 2Graduate School of Biomedical Sciences, Nagasaki University, 3Osaka University of Pharmaceutical Sciences） Design, synthesis, and evaluation of tripeptidemimetics with aryl ketone as inhibitors of SARS-CoV 3CL protease Sho Konno1, Kiyohiko Nakada1, Pillaiyar Thanigaimalai1, Rie Kakiuchi1, Takehito Yamamoto1, Yuri Yamazaki1, Fumika Yakushiji1, Kenichi Akaji2, Yoshiaki Kiso2, Yuko Kawasaki3, Ernest Friere3, Yoshio Hayashi1（1Tokyo University of Pharmacy and Life Sciences, Department of Medicinal Chemistry, 2Department of Medicinal Chemistry, Kyoto Pharmaceutical University, 3Department of Biology, Johns Hopkins University） CREATION OF GAGA METALLO FINGER PROTEIN: ITS STRUCTURE, DNA-BINDING AND REDOX BEHAVIOR Shigeru Negi, Saeko Masuyama, Makiko Yamaoka, Yukio Sugiura （Doshisha Womens University, Faculty of Pharmaceutical Science） Hydrophobic interaction between plasmin inhibitors and the S1' site Yuko Tsuda1,2, Tomonori Baba1, Hidetoshi Fujii1, Koushi Hidaka1, Keigo Gohda3, Naoki Teno4, Keiko Wanaka5 （1Kobe Gakuin University, Faculty of Pharmaceutical Sciences, 2 Kobe Gakuin University, Life Science Center for Cooperative Research, 3 Computer-Aided Molecular Modeling Research Center, Kansai, 4Hiroshima International University, Faculty of Pharmaceutical Sciences, 5Kobe Research Projects on Thrombosis and Haemostasis） The effects of halogenation of Phe-phenyl group of two consecutive Phe residues present in neuropeptide substance P on its specific receptor interaction Ryo Nakamura, Hirokazu Nishimura, Keitaro Suyama, Takeru Nose, Yasuyuki Shimohigashi （Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, Risk Science Research Center） Role of Proline in Heme Regulatory Motifs of Heme Oxygenase-2 Ryoya Tsurusawa1, Shinya Koga1, Yuichiro Higashimoto2, Masato Noguchi3, Hiroshi Sakamoto1 （1Kyushu Institute of Technology, Graduate School of Computer Science and Systems Engineering, Department of Bioscience and Bioinformatics, 2Kurume University School of Medicine, Department of Chemistry, 3Kurume University School of Medicine, Department of Medical Biochemistry） A Physico-Chemical Approach toward the Oligomerization Mechanism of Adiponectin with its Collagen like Domain Peptide Ayako Takuwa1, Takuya Yoshida1, Misako Taichi2, Yuji Nishiuchi2, Tadayasu Ohkubo1, Yuji Kobayashi3 （1Graduate School of Pharmaceutical Sciences, Osaka University, 2 SAITO Research Center, Peptide Institute, Inc., 3Osaka University of Pharmaceutical Sciences）

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CH-π interaction between I308 and Y310 residues is required for self assembly of Full length Tau Koshiro Sogawa1, Ryouhei Okuda1, Katsuhiko Minoura1, Yasuko In1, Toshimasa Ishida1, Taizo Taniguchi2, Koji Tomoo1 （1Department of Physical Chemistry, Osaka University of Pharmaceutical Sciences, 2Department of Pharmaceutical Health Care, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University） SOLUTION STRUCTURE AND FUNCTIONAL RESIDUES OF A SHORT-CHAIN INSECTICIDAL TOXIN LAIT1 FROM THE VENOM OF SCORPION LIOCHELES AUSTRALASIAE Masahiro Miyashita1, Shoichiro Horita2, Takuya Miyakawa2, Yoshiaki Nakagawa1, Koji Nagata2, Hisashi Miyagawa1, Masaru Tanokura （1Kyoto University, Graduate School of Agriculture, Division of Applied Life Sciences, 2University of Tokyo, Graduate School of Agricultural and Life Sciences, Department of Applied Biological Chemistry） Effects of the halogenation of Phe-phenyl group of two concecutive residues in endomorphin-2 on the interaction with the μ-opioid receptors Kanako Nishio, Hirokazu Nishimura, Keitaro Suyama, Yoshinori Abe, Ayami Matsushima, Takeru Nose, Yasuyuki Shimohigashi （Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, Risk Science Research Center） Structural analysis of delta opioid receptor dimer by bivalent deltorphin II analogs Natsuki Ito1,2, Hirokazu Nishimura1,2, Ayami Matsushima1,2, Takeru Nose1,2, Tomasso Costa3, Yasuyuki Shimohigashi1,2 （1Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, Risk Science Research Center, 2Instituto Superiore de Sanità, Laboratorio di Farmacologia） THE STRUCTURE-ACTIVITY RELATIONSHIP STUDY OF THE C-TERMINAL PART OF PHEROMONE BIOSYNTHESIS-ACTIVATING NEUROPEPTIDE Takeshi Kawai1, Jae Min Lee2, Koji Nagata1, J. Joe Hull3, Shogo Matsumoto2, Masaru Tanokura1, Hiromichi Nagasawa1 （1Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2Molecular Entomology Laboratory, RIKEN, Advanced Science Institute, 3USDA-ARS Arid Land Agricultural Research Center） AFFINITY LABELING OF THE ORL1 NOCICEPTIN RECEPTOR BY CYS(Npys)-ELONGATED RYYRIK PEP Ayami Matsushima1, Hirokazu Nishimura1, Shogo Inamine1, Shiho Uemura2, Yasuyuki Shimohigashi1 （1Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, Risk Science Research Center, 2Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry） IDENTIFICATION OF THE AMINO-ACID RESIDUES IMPORTANT FOR THE RECOGNITION OF SILKMOTH PHEROMONE BIOSYNTHESIS-ACTIVATING NEUROPEPTIDE BY ITS RECEPTOR Koji Nagata1, Takeshi Kawai1, Tatsuki Ebisawa1, Kou Hayakawa1, Jae Min Lee2, J. Joe Hull3, Shogo Matsumoto2, Hiromichi Nagasawa1, Masaru Tanokura1 （ 1University of Tokyo, Graduate School of Agricultural and Life Sciences, 2RIKEN Advanced Science Institute, 3USDA-ARS Arid Land Agricultural Research Center） Receptor-binding characteristics of tritium-labeled pure antagonist peptide for hyperalgesic nociceptin ORL1 receptor Shogo Inamine1, Hirokazu Nishimura1, Jinglan Li2, Ayami Matsushima1, Takeru Nose1, Tommaso Costa3, Yasuyuki Shimohigashi1 （1Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, Risk Science Research Center, 2Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, 3Istituto Superiore di Sanità, Laboratorio di Farmacologia） FUNCTIONAL ANALYSIS OF A HISTIDINE RESIDUE ESSENTIAL FOR RECEPTOR ACTIVATION OF DELTA OPIOID RECEPTOR Yoshinori Abe1, Takashi Matsuo2, Hirokazu Nishimura1, Jinglan Li2, Takeru Nose1, Tommaso Costa3, Yasuyuki Shimohigashi1 （1Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, Risk Science Research Center, 2Kyushu University, Faculty and Graduate School of Sciences, Department of Chemistry, 3Istituto Superiore di Sanità, Laboratorio di Farmacologia）

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SYNTHESIS OF PEPTOIDMIMETIC INHIBITORS TARGETING POLO-BOX DOMAIN OF POLO-LIKE KINASE 1 Ravichandran N. Murugan1, Mija Ahn1, Kyung S Lee2, Shin Won Kwang3, Jeong-Kyu Bang1 (1Division of Magnetic Resonance Research, Korea Basic Science Institute、2Center for Cancer Research, National Cancer Institute, National Institute of Health、3Department of Chemistry, Pusan National University) Elucidating the effects of Epsin derived amphipathic peptide on cell-membrane architecture Silvia Pujals1, Kentaroh Taniuchi2, Hiroki Miyamae1, Masato Umeda2, Shiroh Futaki1 （1Kyoto University, Institute for Chemical Research, 2Kyoto University, Graduate School of Engineering） METAL-MEDIATED LEAKAGE CONTROL BY HISTIDINE-CONTAINING ALAMETHICIN ANALOGS Daisuke Noshiro, Koji Asami, Shiroh Futaki （Institute for Chemical Research, Kyoto University） Function of heme regulatory motif in the oxidative modification for transcriptional regulation Taira Tatsukawa1, Takeshi Uchida2, Koichiro Isimori2 (1Graduate School of Chemical Sciences and Engineering, Hokkaido University, 2Department of Chemistry, Faculty of Science, Hokkaido University) Functional analysis of HutZ from Vibrio cholera Yukari Sekine1, Takeshi Uchida2, Koichiro Ishimori2 （1Graduate School of Chemical Sciences and Engineering, Hokkaido University, 2Department of Chemistry, Faculty of Science, Hokkaido University） Cooperative communication between the mature and the propeptide region in prouroguanylin during folding Yu-ichiro Yoshida1, Masaki Okumura2, Shigeru Shimamoto1, Kyohei Hasegawa1, Hiroshi Yamaguchi2 ,Yuji Hidaka1 （1Kinki University, Graduate School of Science and Engineering, 2Kwansei Gakuin University, School of Science and Technology） INFLUENCES OF THREE-DIMENSIONAL STRUCTURES OF PEPTIDES ON STEREOINVERSIONS OF ASPARTIC ACID RESIDUES Akifumi Oda1,2, Kana Kobayashi1, Ohgi Takahashi1 （1Tohoku Pharmaceutical University, Faculty of Pharmaceutical Sciences, 2Osaka University, Institute for Protein Research） Theoretical conformation analysis of amino-acid residue designed as analogue of peptide nucleic acids Masahito Oka, Koji Inai （Osaka Prefecture University, Faculty of Liberal Arts & Sciences） CONFORMATION ANALYSIS OF LOOP REGION PEPTIDES IN THE LAMININ ALPHA CHAIN LG4 MODULES BY MOLECULAR DYNAMICS SIMULATIONS Hironao Yamada （Tokyo University of Phamacy and Life Sciences, School of Phamacy） Synthesis and Conformational Analysis of a Dcp-containing Homooligopeptides Yasuko In1, Katsuhiko Minoura1, Shio Fujioka2, Misai Takeda2, Takashi Murashima2, Takashi Yamada2, Toshimasa Ishida1 （1Osaka University of Pharmaceutical Sciences, Department of Physical Chemistry, 2Konan University, Faculty of Science and Engineering,Department of Chemistry） COMPUTATIONAL ANALYSIS OF ASSOCIATED PEPTIDES IN AQUEOUS SOLUTION USING MOLECULAR DYNAMIC SIMULATION Koji Inai, Maya Taniguchi, Masahito Oka （Osaka Prefecture University, Faculty of Liberal Arts and Sciences） DESIGN OF STABLE HELICAL PEPTIDES Masaaki Kurihara1, Yosuke Demizu1, Saori Nagoya1, Yukiko Sato1, Mitsunobu Doi2, Masakazu Tanaka3 （1Division of Organic Chemistry, National Institute of Health Sciences, 2Osaka University of Pharmaceutical Sciences, 3Graduate School of Biomedical Sciences, Nagasaki University） SECONDARY STRUCTURAL ANALYSIS OF ILE-CONTAINING ELASTIN-DERIVED PENTAPEPTIDE ANALOGUES Suguru Taniguchi, Noriko Watanabe, Takao Hattori, Yuko Yamasaki, Iori Maeda （Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology）

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EXPRESSION AND STRUCTURAL ANALYSIS OF A RECOMBINANT ANTIBACTERIAL PEPTIDE, CECROPIN P1 Taichi Nakazumi1, Chihiro Sakai1, Shiori Maehana1, Tomoyasu Aizawa1, Eri Hojo3, Takashi Matsumoto3, Masakatsu Kamiya1, Yasuhiro Kumaki2, Takashi Kikukawa1, Makoto Demura1, Keiichi Kawano1 （1Hokkaido University, Faculty of Advanced Life Science, 2Hokkaido University, Graduate School of Science, 3R&D Center, Nippon Meat Packers, Inc.） Structural difference between the wild type and the constitutively active mutant transmembrane-juxtamembrane regions of receptor tyrosine kinase revealed by solid state NMR and Fluorescence spectroscopy Chihiro Matsushita1, Yudai Miyazawa1, Hiroko Tamagaki1, Steven O Smith2, Saburo Aimoto1, Takeshi Sato1 （1Osaka University, Institute of Protein Research, 2Stony Brook University） EXPRESSION, PURIFICATION AND NMR CHARACTERIZATION OF THE CYCLIC RECOMBINANT FORM THE FIRST EXTRACELLULAR LOOP OF THE TRANSMEMBRANE PROTEIN HALORHODOPSIN. Yoshihiko Takanashi1, Masakatsu Kamiya1, Yasuhiro Kumaki2, Takashi Kikukawa1, Tomoyasu Aizawa1, Keiichi Kawano1, Makoto Demura1 （1Graduate School of Life Science, Hokkaido University, 2Graduate School of Science, Hokkaido University） NMR STRUCTURE AND INTERACTION OF ANTIMICROBIAL PEPTIDE TACHYPLESIN I WITH LIPOPOLYSACCHARIDE Takahiro Kushibiki1, Masakatsu Kamiya1, Tomoyasu Aizawa1, Yasuhiro Kumaki2, Takashi Kikukawa1, Makoto Demura1, Shunichiro Kawabata3, Keiichi Kawano1 （1Graduate School of Life Science, Hokkaido University, 2Graduate School of Science, Hokkaido University, 3Department of Biology, Faculty of Sciences, Kyushu University） EFFECT OF HYDRATION in Pro-fProR-Gly REGION ON THE STABILITY OF THE COLLAGEN TRIPLE HELIX Daisuke Motooka1, Kazuki Kawahara2, Shota Nakamura3, Masamitsu Doi4, Yuji Nishiuchi5, Takashi Nakazawa6, Tadayasu Ohkubo1, Yuji Kobayashi7 （1Graduate School of Pharmaceutical Sciences, Osaka University, 2Center for Research of Ancient Culture, Nara Women’s University, 3Research Institute for Microbial Diseases, Osaka University, 4 Department of Materials Science, Wakayama National College of Technology, 5SAITO Research Center, Peptide Institute, Inc., 6Department of Chemistry, Nara Women’s University, 7Osaka University of Pharmaceutical Sciences） FOLDING ANALYSIS OF PROUROGUANYLIN VIA SPECIFIC FOLDING INTERMEDIATES USING PROTEIN DISULFIDE ISOMERASE Masaki Okumura1, Yu-ichiro Yoshida2, Takuma Maekawa1, Kumiko Sumi1, Hiroshi Yamaguchi1, Yuji Hidaka2 （1School of Science and Technology, Kwansei Gakuin University, 2Graduate School of Science and Engineering, Kinki University） TOPICAL MIGRATION OF MEMBRANE-ASSOCIATED MOLECULES INDUCED BY DIRECT INFLUX OF ARGININE-RICH PEPTIDES INTO CELLS Hisaaki Hirose, Toshihide Takeuchi, Ikuhiko Nakase, Shiroh Futaki （Kyoto University, Institute for Chemical Research） SYNTHESIS OF NOVEL OLIGOCATIONIC PEPTIDES WHICH BIND TO A-TYPE NUCLEIC ACID DUPLEXES Yusuke Maeda, Rintaro Iwata, Takeshi Wada （The University of Tokyo, Graduate School of Frontier Sciences, Department of Medical Genome Sciences） CONJUGATES OF ANTISENSE OLIGONUCLEOTIDES WITH AIB-CONTAINING PEPTIDE: EFFECTS ON CELLULAR UPTAKE AND ANTISENSE EFFECT Shun-ichi Wada, Yasunari Hitora, Saori Yokoe, Hidehito Urata （Osaka University of Pharmaceutical Sciences） AN APPRACH TO EXPLOR PROTEINS INVOLVED IN THE INTERNALIZATION OF ARGININE-RICH PEPTIDES USING PHOTOCROSSLINKING Yoshimasa Kawaguchi1, Gen Tanaka1, Yasunori Fukuda1, Ikuhiko Nakase1, Yasumaru Hatanaka2, Shiroh Futaki1 （1Kyoto University, Institute for Chemical Research, 2 University of Toyama, Guraduate School of Medicine and Pharmaceutical Science）

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Correlation of structure in solution and lipid affinity of apolipoproteinA-I mimetic peptide Ryuta Adachi1, Kousuke Oniki3, Haruhiko Aoyagi2, Satomi Abe3, Yoshinari Uehara3, Keijiro Saku3, Keiichi Yamada4, Setsuko Ando1 （1Fukuoka University, Faculty of Science, Department of Chemistry, 2Kyushu Nutrition Welfare University, 3Fukuoka University School of Medicine, Department of Cardiology, 4Gunma University, Department of Chemistry and Chemical Biology） Synthesis and properties of alendronic acid containing the dipeptide Yurika Kubo1, Miho Yukawa2, Hirohito Ikeda2, Hatsumi Aki2, Toshihisa Ueda3, Setsuko Ando1 （1Fukuoka University, Faculty of Science, Department of Chemistry, 2Fukuoka University, Faculty of Pharmaceutical, 3Department of Applied Biochemistry and Food Science, Saga University） PROBING THE DIFFERENTIAL PHOSPHOTHREONINE AND METAL SELECTIVITY OF HUMAN PPM1 PHOSPHATASE FAMILY Jose Isagani Janairo, Ryo Iwamuro, Shunji Kaya, Hiroaki Yagi, Yoshiro Chuman, Toshiaki Imagawa, Kazuyasu Sakaguchi （Hokkaido University, Faculty of Science, Department of Chemistry） DESIGN AND SAR STUDY OF TRIPEPTIDIC BACE1 INHIBITORS Yoshio Hamada1, Harichandra D. Tagad2, Yoshiaki Kiso3 （1Kobe Gakuin University, Faculty of Pharmaceutical Sciences, 2Kyoto Pharmaceutical University, Center for Frontier Research in Medicinal Science, 3Nagahama Institute of Bio-Science and Technology, Laboratory of Peptide Science） Milk-derived peptides and their depigmenting activities Sae-Rom Kong1, Seon-Yeong Kwak1, Young-Bu Kim2, Young-Ae Yoo2, Yoon-Sik Lee1 （1Department of Chemical & Biological Engineering, Seoul National University, 2R&D Center, I-Peeres Cosmetics Ltd.） Development of vasoactive intestinal peptide derivative-loading PLGA nanospheres with improved duration of action Takuya Matsui1, Kazuki Kuriyama1, Kumiko Ogawa1, Yoshiki Kojo1, Takahiro Mizumoto2, Satomi Onoue1, Shizuo Yamada1 （1University of Shizuoka, School of Phermaceutical science, 2Department of Product Development, ILS Inc） Oxytocin increases the excitability of spinal superficial dorsal horn neuron in adult male rats Chang-Yu Jiang, Tsugumi Fujita, Tao Liu, Kotaro Mizuta, Hai-Yuan Yue, Eiichi Kumamoto （Department of Physiology, Faculty of Medicine, Saga University） CARNOSINE, HISTIDINE-RELATED DIPEPTIDE, POSSESS THE CNS DEPRESSANT EFFECTS ON MICE AND ITS ACTION MECHANISM Noriyuki Usami1, Nobuyuki Kishi3,4, Toshiyuki Kimura5, Ikuo Yamamoto2,3 （1Ohu University, School of Pharmaceutical Sciences, 2Kyushu University of Health and Welfare, School of Pharmaceutical Sciences, 3Quality of Life Research Institute in Kyushu University of Health and Welfare, 4Tomitaka Pharmacy, Hyuga, Miyazaki, 5Hokuriku University, Faculty of Pharmaceutical Sciences） SCREENING OF BIOLOGICALLY ACTIVE SEQUENCES FROM THE LAMININ GAMMA 1, 2, AND 3 CHAIN SHORT ARM REGIONS Takashi Watari, Yoichiro Tanaka, Ayuko Kawami, Fumihiko Katagiri, Kentaro Hozumi, Yamato Kikkawa, Motoyoshi Nomizu （Tokyo University of Pharmacy and Life Sciences, School of Pharmacy） SINGLE-CHAIN ANTIBODIES SPECIFIC TO THE NARCOTICS ISOLATED FROM IMMUNE PHAGE LIBRARIES Miho Matsukizono1, Mariko Kamegawa2, Koichi Tanaka1, Shinya Kohra3, Koji Arizono4, Yuta Hamazoe1, Kazuhisa Sugimura1 （1Kagoshima University, Graduate School of Science and Engineering, Biotechnology and Chemical Engineering, Department of Chemistry, 2Genenet CO., LTD., Division of Research and Development, 3Nagasaki University, Faculty of Environmental Studies, 4Prefectural University of Kumamoto, Division of Food and Health Environment） NEW PACAP38 ANALOGUE WITH IMPROVED STABILITY: PHYSICOCHEMICAL AND BIOCHEMICAL CHARACTERIZATION Satomi Onoue1, Junko Hanato1, Kazuki Kuriyama1, Takahiro Mizumoto2, Shizuo Yamada1 （1University of Shizuoka, School of Pharmaceutical Sciences, Department of Pharmacokinetics and Pharmacodynamics, 2ILS Inc., 3American Peptide Company）

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DSENSITIZATION OF Cry j 1 AS A MOJOR ALLERGEN OF JAPANESE CEDAR POLLEN. Satomi Kai, Shuhei Hashiguchi, Kazuhisa Sugimura （Kagoshima University, Sience and Engineering, Department of Chemistry and Biotechnology） Eukaryotic elongation factor 1A2 participates in the expression of antiadhesive effect of FNIII14, a peptide cleaved from Fibronectin Takuya Akasi, Chihiro Kojima, Takuya Iyoda, Fumio Fukai （Tokyo University of Science, Faculty of Pharmaceutical Sciences, Department of Molecular Patho-Physiology） COMBINATION OF A TENASCIN-C PEPTIDE WITH PDGF SYNERGISTICALLY ENHANCES MIGRATION AND PROLIFERATION OF GLIOBLASTOMA CELLS Tatsuya Fujisawa, Motomichi Fujita, Tatsuya Takai, Takuya Iyoda, Fumio Fukai （Department of Molecular Patho-Physiology, Faculty of Pharmaceutical Sciences, Tokyo University of Science） Creation of artificial epidermal growth factor receptor activated by coiled-coil peptides Ikuhiko Nakase, Katsuhiro Osaki, Shinya Okumura, Shiroh Futaki （Institute for Chemical Research, Kyoto University） SCREENING OF CANCER-CELL TARGETING PEPTIDES Takayuki Fukuda, Kohei Shingai, Masahiko Sisido （Okayama University, Department of Medical and Bioengineering Science, the Graduate School of Natural Science and Technology） DEVELOPMENT OF PEPTIDE PET TRACER USING 68Ge/Ga GENERATOR FOR DIAGNOSIS OF ALZHEIMER'S DISEASE Hiroshi Yamaguchi1, Yasuhiro Kuroda2, Masanobu Ibaraki1, Kazuhiro Nakamura1, Kaoru Satou1, Tomomi Ohmura1, Shizuaki Murata2, Kentaro Hatano3, Kengo Ito3, Toshibumi Kinoshita1 （1Akita Research Institute for Brain and Blood Vessels, 2Graduate School of Environmental Studies, Nagoya University, 3Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology） Synthesis and in vivo Evaluation of Radiohalogen-Labeled Antitumor Cyclic Peptides Keiichi Yamada1, Shigeki Watanabe2, Yasuhiro Oshima2, Hirofumi Hanaoka3, Narutaka Tsukui1, Chikako Takano1, Aiko Yamaguchi4, Hiroyuki Oku1, Noriko Ishioka2 （1Gunma University, Graduate School of Engineering, Department of Chemistry and Chemical Biology, 2Japan Atomic Energy Agency, Quantum Beam Science Directorate, Medical Radioisotope Application Group, 3Chiba University, Graduate School of Pharmaceutical Sciences, Department of Molecular imaging and radiotherapy, 4Gunma University School of Medicine） SYNTHESIS OF [68Ga]DOTA-FAMP AND PET IMAGING STUDY WITH ATHEROSCLEROTIC PLAQUES Koki Hasegawa1, Emi Kawachi2, Ren Kuwabara3, Eiji Yahiro2, Emi Hayashinaka1, Yasuhiro Wada1, Tsuneo Yano1, Yoshinari Uehara2, Shin-ichiro Miura2, Keijiro Saku2, Yasuyoshi Watanabe1 （1Center for Molecular Imaging Science, RIKEN, 2Department of Cardiology, Fukuoka University Faculty of Medicine, 3Faculty of Pharmaceutical Science, Kobe Gakuin University） DESIGNED ANTIGENS BASED ON THE DYNAMIC STRUCTURAL CHANGES OF GP41 FOR DEVELOPMENT OF EFFECTIVE HIV-1 VACCINES Wataru Nomura1, Chie Hashimoto1, Toru Nakahara1, Aki Ohya1, Kosuke Miyauchi2, Kenji Ohba3, Tetsuo Narumi1, Haruo Aikawa1, Jun Komano2, Naoki Yamamoto3, Hirokazu Tamamura1 （1Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, 2National Institute of Infectious Diseases, AIDS research center, 3National University of Singapore, Yong Loo Lin School of Medicine, Department of Microbiology） HIGHLY SENSITIVE LC/MS SCREENING OF CANCER CELL-BINDING PEPTIDES Kohei Shingai, Takayuki Fukuda, Masahiko Sisido （ Department of Medical and Bioengineering Science, the Graduate School of Natural Science and Technology, Okayama）

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REPRESSION OF p53 TRANSCRIPTIONAL ACTIVITY BY INHIBITORY PEPTIDE VIA HETEROTETRAMERIZATION Junya Wada, Rui Kamada, Yoshiro Chuman, Toshiaki Imagawa, Kazuyasu Sakaguchi （Hokkaido University, Faculty of Science, Department of Chemistry） DE NOVO DESIGNED NITRIC OXIDE SENSOR PROTEIN CONSISTED OF IRON COMPLEX‐PEPTIDE CONJUGATE Hiroshi Miyazaki1, Kenji Usui2, Satoshi Fujii2 （1Faculty of Frontiers of Innovative Research in Science and Technology , Konan University, 2Frontier Institute for Biomolecular Engineering Research, Konan University） EVALUATION OF INHIBITORY ACTIVITIES OF CURCUMIN DERIVATIVES USING BACE1 AND AMYLOID BETA PEPTIDE Hideo Aoki1, Hiroyuki Konno1, Yugo Saito1, Hitoshi Endo1, Akira Sanjho2, Kenichi Akaji3 （1Yamagata University, Graduate School of Science and Technology,Department of Biochemical Engineering, 2Protein Wave Corporation, 3Kyoto Pharmaceutical University, Department of Medicinal Chemistry） DETECTION OF AMYLOID OLIGOMERS USING SURFACE-ENGINEERED FLUORESCENT PROTEINS PRESENTING AMYLOID-LIKE BETA-SHEET STRUCTURES Tsuyoshi Takahashi1, Hisakazu Mihara2 （1Gunma University, Advanced Scientific Research Leaders Development Unit, 2Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology） INTRACELLULAR MOLECULAR DYNAMICS OF N-TERMINAL MOTIF OF MYRISTOYLATED PEPTID Haruka Morita1, Setsuko Ando1, Kentarou Okuma1, Noriyoshi Nagahora1, Yasunori Aizawa2, Makiha Fukuda2, Hiroyuki Nakagawa3, Kosei Shiozi1 （1Department of Chemistry, Faculty of Science, Fukuoka University, 2Center for Biological Resources and Informatics, Department of Life Science, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, 3Department of Earth System Science, Faculty of Science, Fukuoka University） SCREENING OF DESINED PEPTIDES FOR BINDERS TO A DNA G-QUADRUPLEX STRUCTURE Noriko Matsui1, Keita Kobayashi1, Kenji Usui1,2 （1Konan University,Faculty of Frontiers of Innovative Research in Science and Technology, 2Konan University, Frontier Institute for Biomolecular Engineering Research） DEVELOPMENT OF PNA-PEPTIDES CONTROLING DNA G-QUADRUPLEX STRUCTURES DEPENDING ON PROTEASE ACTIVITY Keita Kobayashi1, Kenji Usui1,2, Naoki Sugimoto1,2 （1Konan University,Faculty of Frontiers of Innovative Research in Science and Technology, 2Konan University, Frontier Institute for Biomolecular Engineering Research） INTENSE BLUE FLUORESCENCE OF TAG-PROBE SYSTEMS BASED ON A LEUCINE ZIPPER ASSEMBLY Wataru Nomura, Hiroshi Tsutsumi, Seiichiro Abe, Atsumi Mori, Tetsuo Narumi, Haruo Aikawa, Hirokazu Tamamura （Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering） SYNTHESIS AND CHARACTERIZATION OF ZINC CHELATOR CONJUGATED WITH CATIONIC PEPTIDE Yutaka Hitomi1, Akihiro Kashida1, Akiko Nomura2, Masanori Hayashi1, Masahito Kodera1 （1Doshisha University, Faculty of Science and Engineering, Department of Molecular Chemistry and Biochemistry, 2Doshisha University, Nanoscience Research Center） Detection of methylation status of DNA by designed phosphopeptide Akiko Nomura1, Akimitsu Okamoto1 （1RIKEN, 2Doshisha University, Nanoscience Research Center）

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Design of a Dual-Color Detection System for Caspase Activities Using a Combination of Split-Fluorescent Proteins and Split-Intein Seiji Sakamoto, Mika Terauchi, Shusaku Taki, Tanner Ian Kim, Yasuyuki Araki, Takehiko Wada （Tohoku University, Institute of Multidisciplinary Research for Advanced Materials） Fmoc Solid-Phase Synthesis and Photochemical Properties of Oligoarginines Possessing the Chlorin Macrocycle at the N-Terminal Yoshitaka Saga, Hiroshi Okazaki, Yousuke Shimoura （Kinki University, Faculty of Science and Engineering, Department of Chemistry） DETECTION OF MALARIA ANTIBODY USING PEPTIDE ANTIGEN IMMOBILIZED NANO- SPHERES Hiroyuki Oku1, Kazuhiko Yano2, Megumi Fukumoto2, Mai Fukuno1, Ayano Iwasaki1, Keiichi Yamada1, Shin Hasegawa3, Yasunari Meakawa3, Kumiko Sato4, Shigeyuki Kano2 （1Department of Chemistry & Chemical Biology, Gunma University, 2Research Institute, National Center for Global Health & Medicine, 3Japan Atomic Energy Agency, 4Gunma University） Interaction Between a Virus Capsid Protein and a Water-Soluble Cationic Porphyrin Takayuki Ueda1, Hiroaki Kitagishi1, M.G. Finn2, Koji Kano1 （1Department of Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, 2Department of Chemistry, The Scripps Research Institute） SELECTIVE LIPOSOME BINDING OF PROTEIN MODIFIED WITH HYDROPHOBIC COMPOUNDS AT THE C-TERMINAL Yurina Endo1, Yasunao Hattori1, Kenichi Akaji2, Kenta Teruya1 （1Kyoto Prefectural University of Medicine, Department of Chemistry, 2Kyoto Pharmaceutical University, Department of Medicinal Chemistry） CELLULAR UPTAKE OF A SUPRAMOLECULAR CO-RECEPTOR WITH AN OCTAARGININE PEPTIDE Satoshi Hatada, Toshiaki Itakura, Hiroaki Kitagishi, Koji Kano （Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University） MOLECULAR DISSECTION OF LAMININ-111 USING PEPTIDE-CHITOSAN MATRIX TO CONSTRUCT LAMININ MIMICKED BIOMATERIALS Kentaro Hozumi, Ayano Sasaki, Yuji Yamada, Fumihiko Katagiri, Yamato Kikkawa, Motoyoshi Nomizu （Tokyo University of Pharmacy and Life Sciences, School of Pharmacy） SYNTHESIS AND BIOLOGICAL ACTIVITIY OF ANTIMICROBIAL PEPTIDE-POLYMER CONJUGATES Makoto Nakamura1, Hideaki Suzuki2, Ai Asaoka3, Yusuke Kohno2, Seiji Tokino1, Tomio Nagano2, Jun Ishibashi3 （1Industrial Technology Center of Wakayama Prefecture, 2Japan Innovative Tecnologies & Solutions for Ultimate Bio-Objectives, 3National Institute of Agrobiological Sciences） Extraction of collagen from fishery waste and effects of cross-linking structures Fumio Nakazawa1, Junko Kuwahara2, Hajime Mita3 （1Master Program of Life, Environment and Materials Science, Graduate school of Fukuoka Institute of Technology, 2 Department of Life, Environment and Materials Science, Faculty of Engineering, Fukuoka Institute of Technology, 3Department of Life, Environment and Materials Science, Faculty of Engineering, Fukuoka Institute of Technology） NANOSTRUCTURE FORMED BY BIOMINERALIZATION PEPTIDE OLIGOMERIZED VIA p53 TETRAMERIZATION Tatsuya Sakaguchi, Rui Kamada, Yoshiro Chuman, Kazuyasu Sakaguchi （Hokkaido University, Faculty of Science, Department of Chemistry） Cell penetration and application of alpha-helical peptides conjugated with gold nanoparticles Hyejin Park1, Tsuyoshi Takahashi2, Hiroshi Tsutsumi1, Hisakazu Mihara1 （1Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 2Advanced Scientific Research Leaders Development Unit, Gunma University）

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Organic-Inorganic Complex of Polylysine and Fluorohectorite Mami Turuyama1, Hiroshi Kanamaru1, Nobuyoshi Miyamoto2, Hjime Mita2 （1Fukuoka Institute of Technology, 2Fukuoka Institute of Technology） Detection of protease reactions by anomalous reflection of gold Kenichi Tajima1, Syahir Amir1, Kotaro Kajikawa2, Hisakazu Mihara1 （1Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, 2Tokyo Institute of Technology, Interdisciplinary Graduate School of Science and Engineering） Detection of lectin proteins using glycopeptide-modified gold nanoparticles Hiroyuki Okusa1, Hyejin Park1, Hiroshi Tsutsumi1, tsuyoshi Takahashi2, Hideya Yuasa3, Hisakazu Mihara1 （1Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 2Advanced Scientific Research Leaders Development Unit, Gunma University, 3Department of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology） LOW-POLARITY ENVIRONMENT IS IMPORTANT FOR THE FORMATION OF TOXIC AMYLOID β AGGREGATES Saori Fukunaga, Takahiro Yamaguchi, Yoshiaki Yano, Masaru Hoshino, Katusmi Matsuzaki （Graduate School of Pharmaceutical Sciences, Kyoto University, Department of Analytical Chemistry） Structural characterisitics of Thr-Gly dipeptide repeat in the Drosophila clock protein PERIOD Ayaka Matsuo1, Hirokazu Nishimura1, Masayuki Nakamura1, Keita Koga1, Miho Sumiyoshi2, Ayami Matsushima1, Takeru Nose1, Miki Shimohigashi2, Yasuyuki Shimohigashi1 （1Laboratory of Structure-Function Biochemistry, Department of Chemistry, Faculty and Graduate School of Sciences, and Risk Science Research Center, Kyushu University, 2Division of Biology, Department of Earth System of Science, Faculty of Science, Fukuoka University） Synthesis of beta-chiral peptide nucleic acids and their DNA binding properties Toru Sugiyama1, Yasutada Imamura2, Yosuke Demizu3, Masaaki Kurihara3, Masashi Takano4, Atsushi Kittaka4 （1The University of Tokyo, Graduate School of Arts and Sciences, Department of Life Sciences, 2Kogakuin University, Faculty of Engineering, 3 Ministry of Health and Welfare, National Institute of Health Sciences, 4Teikyo University, Faculty of Pharmaceutical Sciences） MOLECULAR DYNAMICS SIMULATIONS FOR THE FORMATION OF SECONDARY STRUCTURES OF 17-RESIDUE PEPTIDES Hiroki Kimoto, Chikako Nakazawa, Takuzo Kurotsu （National Defense Academy, Department of Applied Chemistry） AGGREGATION OF CHLOROPHYLLS IN CHLOROPHYLL-PROTEINS Toru Oba1, Hitoshi Tamiaki2 （1Utsunomiya University, Graduate School of Engineering, Department of Material and Environmental Chemistry, 2Ritsumeikan University, Institute of Science and Engineering） SEQUENCE ANALYSIS OF NATIVE PROTEINS BY AUTOCORRELATION FUNCTION METHOD Koji Inai, Tomomi Nitta, Masahito Oka （Osaka Prefecture University, Faculty of Liberal Arts and Sciences） ANALYSES OF THERMAL PROTEINOID FROM MONOAMMONIUM MALATE AND FORMATION OF PROTEINOID MICROSPHERE. Hiroshi Kanamaru, Mami Tsuruyama, Kouta Hatae, Syouichi Nakamura, Hajime Mita （Department of Life, Environment and Materials Science, Fukuoka Institute of Technology） High level expression of proopiomelanocortin using artificial gene in E. coli cells Tadafumi Konogami1, Kenji Watanabe1, Shigeru Shimamoto1, Ajoy Basak2, Yuji Hidaka1 （1Graduate School of Science and Engineering, Kinki University, 2Regional Protein Chemistry Center, Ottawa Health Research Institute）

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FUNCTIONAL ANALYSIS OF INS-6, ONE OF THE INSULIN-LIKE PEPTIDES IN C. ELEGANS USING PRIMARY CULTURE Takashi Iwasaki1, Maki Komatsu1, Takumi Fujimori2, Tsuyoshi Kawano1 （1Tottori University, Graduate School of Agricultural Sciences, Department of Bioresources Science, 2Tottori University, Faculty of Agriculture, Department of Bioresources Science） EXPRESSION OF ω-AGATOXIN IVA, P-TYPE CALCIUM CHANNEL ANTAGONIST Chanhyung Bae （Korea, GIST, School of life science） INVOLVEMENT OF PPM1D SPECIFIC PRO-LOOP IN REGULATORY MECHANISM OF PPM1D PHOSPHATASE ACTIVITY Hiroaki Yagi, Yoshiro Chuman, Yuuki Kozakai, Toshiaki Imagawa, Kazuyasu Sakaguchi （Hokkaido University, Faculty of Science, Department of Chemistry） Does Escherichia coli thioredoxin improve expression efficiency of recombinant peptides in Pichia pastoris? Yuki Kitamura, Tomoyasu Aizawa, Masakatsu Kamiya, Takashi Kikukawa, Makoto Demura, Keiichi Kawano （Graduate School of Life Science, HokkaidoUniversity） SYNTHESIS AND MASS-SPECTROMETRIC CHARACTERIZATION OF THE PEPTIDE-VEHICLE, PEPTIDE THAT CARRY MOLECULES INTO CELLS Akiyoshi Hirata1, Takeshi Kasama2, Takafumi Ohyama1, Kiyoshi Nokihara1 （1HiPep Laboratories, 2Tokyo Medical and Dental University, Instrumental Analysis Research Center for Life Science） CREATION OF AN ARTIFICIAL RING FINGER WITHOUT A SUBSTRATE AND A TAG Kazuhide Miyamoto （Himeji Dokkyo University, Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Health Care） IMPROVEMENT OF PROBE PEPTIDES FOR COILED-COIL LABELING BY INTRODUCING PHOSPHOSERINES Satoshi Ono, Yoshiaki Yano, Katsumi Matsuzaki （Kyoto University, Graduate School of Pharmaceutical Sciences, Department of Analytical Chemistry） CAGED CERAMIDE WHICH RELEASES PARENT CERAMIDE AFTER UV-INDUCED AMIDE BOND CLEAVAGE FOLLOWED BY INTRAMOLECULAR O-N ACYL TRANSFER Akira Shigenaga, Hiroko Hirakawa, Jun Yamamoto, Keiji Ogura, Masaya Denda, Keiko Yamaguchi, Akira Otaka （The University of Tokushima, Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences） SIMULTANEOUS DETECTION ON ANTIMICROBIAL ACTIVITIES OF DENDRITIC-L-LYS–POLYSTYRENE BEADS AND EXTRACELLULAR ENZYME ACTIVITIES IN CULTURE MEDIA Junko Kuwahara, Mami Uchihira （Department of Life, Environment and Materials Science, Fukuoka Institute of Technology） Affinity purification of alpha-amylases using 0.19 a-amylase inhibitor from wheat kernel Junya Murai1, Yuki Sakai1, Hiroshi Oyama2, Shin Ono1 （ 1University of Toyama, Graduate School of Science and Engineering, 2Setsunan University, Faculty of Science and Engineering, Department of Life Science） CONSTRUCTION OF A NOVEL EXPRESSION SYSTEM FOR CRYPTDIN-4 BY USING INCLUSION BODY FORMATION Yuji Sato, Satoshi Tomisawa, Tomoyasu Aizawa, Naoki Sakai, Masakatsu Kamiya, Takashi Kikukawa, Yasuhiro Kumaki, Makoto Demura, Tokiyoshi Ayabe, Keiichi Kawano （Hokkaido University, Graduate School of Life Science） PROTEASE-IMMOBILIZED MICROREACTOR FOR RAPID AND SITE-SPECIFIC AFFINITY TAG CLEAVAGE Yuya Asanomi1, Yuya Koga2, Hiroshi Yamaguchi4, Masaya Miyazaki1,3, Takeru Nose5, Hiroaki Kodama3, Hideaki Maeda1 (1National Institute of Advanced Industrial Science and Technology (AIST), Measurement Solution Research Center, 2Saga University, Faculty of Science and Engineering, 3Saga University, Graduate School of Science and Engineering, 4 Tokai University, Liberal Arts Education Center, 5Kyushu University, Faculty and Graduate School of Sciences)

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CONTROL OF PROTEIN CRYSTALLIZATION IN NANODROPLETS FOR X-RAY CRYSTAL STRUCTURE ANALYSIS Masatoshi Maeki1, Hiroshi Yamaguchi2, Satoshi Nitahara3, Masahide Kawamoto4, Kenichi Yamashita3, Masaya Miyazaki3, Hideaki Maeda3 （ 1Kyushu University, Interdisciplinary Graduate School of Engineering Sciences, Deapartment of Molecular and Material Sciences, 2Tokai University, Aso Campus, Liberal Arts Education Center, 3 National Institute of Advanced Industrial Sciences and Technology, Measurement Solution Research Center, 4SAGA Light Source, 5Japan Science and Technology Agency, CREST） Length-sorting single-walled carbon nanotubes by bovine alpha-casein on a gel filtration chromatography Shin Ono1, Kazuma Gomi1, Risa Yamakoshi1, Hiroshi Oyama2, Hougen Yamamoto3, Yasushi Maeda3 （1University of Toyama, Graduate School of Science and Engineering, 2 Setsunan University, Faculty of Science and Engineering, Department of Life Science, 3 University of Fukui, Graduate School of Engineering） DEVELOPMENT OF SCREENING FOR TUMOR SUPPRESSOR p53 ACTIVATORS AND INHIBITORS Ken-ichiro Uesugi, Shogo Ohshima, Aya Tanaka, Toshiaki Imagawa, Kazuyasu Sakaguchi （Hokkaido University, Fuculty of Science, Department of Chemistry） STRUCTURAL OPTIMIZATION OF A DNA-PEPTIDE CONJUGATE AIMING AT POTASSIUM ION SENSING REAGENT IN LIVING CELL Shinsuke Ohzawa, Keiichi Ohtsuka, Shinobu Sato, Shigeori Takenaka （Kyushu Institute of Technology, Department of Applied Chemistry） Electrochemical detection of periodontal disease using protease assay Shinichiro Nagata1, Takeshi Ohshima1, Keiichi Ohtsuka1, Shinobu Sato1, Masato Nagayoshi2, Chiaki Kitamura2, Tatsuji Nishihara2, Shigeori Takenaka1 （1Department of Applied Chemistry, Kyushu Institute of Technology, 2Kyushu Dental College） ELECTROCHEMICAL DETECTION OF DNA DUPLEX USING FERROCENYLNAPHTHALENE DIIMIDE DERIVATIVES IN HOMOGENOUS SOLUTION Hirotomo Takenaka, Shinobu Sato, Shigeori Takenaka （Department of Applied Chemistry, Kyushu Institute of Technology） MICROWAVE ACCERALATED FRAGMENTARY HYDROLYSIS OF PROTEIN AND THE SEQUENCE ANALYSIS FOR PROTEOMICS Shokichi Ohuchi1, Miwako Kojo1, Hiroyuki Nakamura1, Takeo Yosimura2, Hiroya Osoegawa1 （1Kyushu Insititue of Technology, Department of Bioscience and Bioinformatics, 2Tokyo University of Science, Department of Applied Biological Science） LIMITED DEGRADATION OF PROTEIN BY ENZYMATIC HYDROLYSIS UNDER MICROWAVE IRRADIATION AND APPLICATION FOR PROTEOMICS ANALYSIS Takeo Yoshimura1, Miwako Kojo2, Yuta Toriuchi2, Hiroyuki Nakamuta2, Hiroya Osoegawa2, Shokichi Ohuchi2 （1Tokyo University of Science, Department of Applied Biological Science, 2Kyushu Insititue of Technology, Department of Bioscience and Bioinformatics）