Product Introductions

3D OCT-1 Maestro

Fully Automated OCT Ease of Use when Capturing Small Pupils - Live Fundus View（OCT-LFV） - 3D Scan without Color Fundus Photography

Cataract Mode 50,000 A-scans/sec. Auto alignment, focus and capture of OCT and color fundus photo Space saving compact instrument design 12×9mm Wide Scan provides measurement and Topography of optic nerve and macula in one scan

3D OCT-2000 FA plus

12mm Wide Scan & 5 Line Cross Scan Ease of Use when Capturing Small Pupils - Live Fundus View（OCT-LFV） - 3D Scan without Color Fundus Photography

50,000 A-scans/sec. OCT + Color + Red-free* + FA + FAF Incomparable Follow-up function 12×9mm Wide Scan & 5 Line Cross Scan NFL / GCL+IPL / NFL+GCL+IPL analysis, Drusen analysis functions Rich normative database Integrated anterior segment module

3D OCT-2000 FA plus Case Report Supervising Editor：Dr. F. Gomi, Sumitomo Hospital, Japan

*digital red-free

DRI OCT-1 Atlantis

1μm Swept Source OCT Deep Range Imaging 1,050nm Swept Source OCT 100,000A-scans/sec. Easy Capture Rich Analysis Function - 7 layers segmentation, 7 Layers Thickness Map Caliper Function - Import Function - Follow-up Examination & Comparison Function

Courtesy : Dr. F. Gomi, Sumitomo Hospital, Japan * 3D OCT-1 Maestro, 3D OCT-2000 FAplus and DRI OCT-1 Atlantis are not available for sale in the US.

75-1 Hasunuma-cho, Itabashi-ku, Tokyo 174-8580, Japan. Phone:3-3558-2523/2522 Fax:3-3965-6898 www.topcon.co.jp

TOPCON MEDICAL SYSTEMS, INC. 111 Bauer Drive, Oakland, NJ 07436, U.S.A. Phone:+1-201-599-5100 Fax:+1-201-599-5250 www.topconmedical.com

TOPCON MEDICAL LASER SYSTEMS, INC. 3130 Coronado Drive Santa Clara,California 95054 USA Phone:+1-408-235-8200 Phone:(USA only)+1-888-760-8657 Fax:+1-408-235-8259 Email: [email protected]

TOPCON CANADA INC. 110 Provencher Avenue, Boisbriand, QC J7G 1N1 CANADA Phone:+1-450-430-7771 Fax:+1-450-430-6457 www.topcon.ca

TOPCON EUROPE MEDICAL B.V. Essebaan 11; 2908 LJ Capelle a/d IJssel; P.O.Box145; 2900 AC Capelle a/d IJssel; THE NETHERLANDS Phone:+31 -(0)10-4585077 Fax:+31 -(0)10-4585045 E-mail: [email protected]; www.topcon.eu

ITALY OFFICE Viale dell' Industria 60; 20037 Paderno Dugnano; (Milano), ITALY Phone:+39-02-9186671 Fax:+39-02-91081091 E-mail: [email protected]; www.topcon.it

DANMARK OFFICE Praestemarksvej 25; 4000 Roskilde, DANMARK Phone:+45-46-327500 Fax:+45-46-327555 E-mail: [email protected] www.topcondanmark.dk

IRELAND OFFICE Unit 276, Blanchardstown; Corporate Park 2 Ballycoolin Dublin 15, IRELAND Phone:+353-18975900 Fax:+353-18293915 E-mail: [email protected]; www.topcon.ie

TOPCON S.A.R.L. BAT A1 3 route de la révolte 93206 SAINT DENIS CEDEX Tel : +33 1 49 21 23 23 Fax : +33 1 49 21 23 24 E-mail:[email protected]; www.topcon.fr

TOPCON DEUTSCHLAND G.m.b.H. Hanns-Martin-Schleyer Strasse 41; D-47877 Willich, GERMANY Phone:+49-(0)2154-8850 Fax:+49-(0)2154-885177 E-mail:[email protected]; www.topcon.de

TOPCON SCANDINAVIA A.B. Neongatan 2; P.O.Box 25; 43151 Mölndal, SWEDEN Phone:+46-(0)31-7109200 Fax:+46-(0)31-7109249 E-mail:[email protected]; www.topcon.se

TOPCON ESPANA S.A. HEAD OFFICE Frederic Mompou 4 Esc. A Bajos 3, 08960 Sant Just Desvern Barcelona, SPAIN Phone:+34-93-4734057 Fax:+34-93-4733932 E-mail: [email protected]; www.topcon.es

TOPCON ( GREAT BRITAIN ) LTD. Topcon House,Kennet Side,Bone Lane,Newbury,Berkshire RG14 5PX United Kingdom Phone:+44-(0)1635-551120 Fax:+44-(0)1635-551170 E-mail:[email protected]; www.topcon.co.uk

TOPCON POLSKA Sp. z. o. o. ul. Warszawska 23; 42-470 Siewierz, POLAND Phone:+48-(0)32-6705045 Fax:+48-(0)32-6713405 www.topcon-polska.pl

TOPCON SINGAPORE MEDICAL PTE. LTD. 1 JALAN KILANG TIMOR #09-01 PACIFIC TECH CENTRE SINGAPORE 159303 Phone:+65-68720606 Fax:+65-67736150 E-mail:[email protected] www.topcon.com.sg

TOPCON INSTRUMENTS ( MALAYSIA ) SDN.BHD. No. D1, (Ground Floor), Jalan Excella 2, Off Jalan Ampang Putra, Taman Ampang Hilir, 55100 Kuala Lumpur,MALAYSIA Phone:+60-(0)3-42709866 Fax:+60-(0)3-42709766

TOPCON INSTRUMENTS ( THAILAND ) CO.,LTD. 77/162 Sinnsathorn Tower, 37th Floor,Krungthonburi Rd.,Klongtonsai, Klongsarn, Bangkok 10600,THAILAND Phone:+66(0)2-440-1152~7 Fax:+66-(0)2-440-1158

TOPCON CORPORATION BEIJING OFFICE Block No.9, Kangding Street Beijing Economic-Technological Development Area, Beijing,100176,CHINA Phone:+86-(0)10-6780-2799 Fax:+86-(0)10-6780-2790

TOPCON CORPORATION SHANGHAI OFFICE 14L Huamin Empire Plaza, No.726, Yan-an Xi Road, Shanghai, 200050, CHINA Phone:+86-(0)21-5238-7722 Fax:+86-(0)21-5237-0761

TOPCON CORPORATION BEIRUT OFFICE P.O.Box 70-1002 Antelias,Beirut, LEBANON Phone:+961-4-523525/523526 Fax:+961-4-521119

TOPCON CORPORATION DUBAI OFFICE P.O.Box 293705,Dubai Airport Free Zone L.I.U. J-12, Dubai, U.A.E Phone:+971-4-299-5900 Fax:+971-4-299-5901

2013 Printed in Japan 2013 09-60 NP GE

3D OCT-2000 FA plus

Case 1: A 53-year-old woman Chief Complaint: Metamorphopsia in the right eye with central visual field defect

Case Reports

Example of oth other scans

OD

Color

The O OCT can detects asymmetrical parts of the macu macula from vertical scanning. A det detail information is available to determine what h is the factor of the visual field defect. Macula (V): Glaucoma Analysis (Macula) 3D Macula

3D Mac Macula cula

Irregular foveal depression Macular Pseudohole (Epiretinal membrane )

3D Optic Disc

Retinal Never Fiber Layer (RNFL) thinning Glaucoma

1

3D Wide Scan

Information from macula to disc can be recognized by wide range imaging

2

3D OCT-2000 FA plus

Case 2: A 35-year-old man Chief Complaint: Anorthopia in the right eye with central visual field defect

Case Reports

Case 3: A 53-year-old man Chief Complaint: Color vision problem in the left eye central visual filed

Central Serous Chorioretinopathy p y

Central Serous Chorioretinopathy p y (Recurrent cas se) case)

Fundus Autofluorescence (FAF) OD

OS

Fundus Autofluorescence (FAF)

Fundus Autofluorescence (F (FAF) (FAF AF))

Sparse hyperautofluorescence. Punctate hypoautofluorescence is observed in some areas. It Could be a sign of subretinal fluid used to be existing in several locations.

Punctate fluorescence was observed at hyperautofluorescent area where subretinal fluid exists / existed.

3D Macula a

3D Macula

Subretinal fluid confined in macula. The leakage does not appearr to be heavy heavy.

Subretinal fluid under the macula. The report clearly indicates a large amount of fluid leakage in the inferior part of the retina.

Fluorescein Angiography (FA)

The place of hypoautofluorescence nce on FAF image and hyperautofluorescence scence on FA image with leakage coincided, ided, indicating an RPE defect. Fundus Autofluorescence Autofluorescen nce (FAF) (FAF)

3

Fluorescein Flu Fl uorescein Angiography Angiography h (FA)

4

3D OCT-2000 FA plus

Case Reports

Case 5: A 79-year-old man Chief Complaint: Visual loss in the left eye and metamorphopsia in both eyes

Case 4: A 58-year-old man Chief Complaint: Anorthopia in the right eye Serous Retinal Pigment Epithelial Detachment

Drusenoid Pigment Epithelial Detachment (PED)

OD

OD

右眼

Fundus Autofluorescence (FAF)

3D Macula

S Serous retinal ti l pigment i t epithelial ith li l detachment including the fovea.

Boundary line of hyperautofluorescence matches with pigment epithelial detachment. The punctate hypoautofluorescence can be shown at the internal region. Boundary of epithelial pigment detachment is observed with increased hyperfluorescence along with the swelling of the pigment epithelium. The internal hypofluorescence can be a sign of pigment epithelium degeneration, or a blockage along with deposition.

Horizontal / Vertical Tomogram

Pigment detachment is shown on both eyes at the macula. (Internal section is shown with high signal gnal – no signal observed inside the epithelium pigment ment detachment at temporal macula (OD)). 左眼 OS

Fundus Autofluorescence (FAF)

The retinal pigment detachment in the macula is shown with both hyperautofluorescence and hypoautofluorescence. Ring-shaped hyperautofluorescence which shows retinal pigment detachment is observed on the temporal area of the right eye.

5

6

Case Reports

3D OCT-2000 FA plus

Case 6: A 69-year-old man Chief Complaint: Gradual visual loss in the right eye

Case 7: A 79-year-old woman Chief Complaint: Vision loss in the left eye and rapid vision loss in the right

Exudative Age-Related Macular Degeneration Polypoidal Choroidal Vasculopathy (PCV)

Exudative Age- Related Macular Degeneration Retinal Angiomatous Proliferation (RAP)

OD

OD

3D Macula

Horizontal Line Scan

Subretinal fluid under the fovea. Retinal pigment epithelium detachment at temporal area. (Signal is shown at the internal region)

The orange-red lesions on color fundus shows a retinal pigment epithelium detachment and a steep swelling in some part with a high internal signal.

OD

OS

5 Line Raster Scan

Edema and uneven pigment epithelium detachment observed in both eyes in the macula.

The left eye shows hyperautofluorescence in the inferior part of macula, which indicates a pigment epithelial tear.

OD

Fundus Autofluorescence (FAF)

7

Ring-shaped hyperautofluorescence which shows retinal pigment detachment. Pale hyperautofluorescence which is a sign of subretinal fluid

OD

OS

Both eyes show multiple punctate hyperautofluorescence. (Reticular Pseudo Drusen) (Re

Fundus Autofluorescence (FAF)

8

3D OCT-2000 FA plus

Case 8: A 65-year-old woman Chief Complaint: Recent vision loss in the right eye

Case Reports

Other Cases

Choroidal neovascularizatio neovascularization on o n obs observed in angioid streaks patient

Pigmentary retinal degeneration case1

OS

Color OD

Fundus Autofluorescence (FAF)

Horizontal Line Scan

Fundus Autofluorescence (FAF)

A degeneration at peripheral region is observed with patchy hypoautofluorescence . The healthy part of outer segment appears hyperfluorescent.

OD

The image shows the streaked hypoautofluorescence from the optic disc. Pale ring-shaped hyperautofluorescence at the superior nasal in the fovea. Uneven hyperautofluorescence.

OS

case2

Serous detachment at the macula. Subretinal fluid at the temporal macula. Uneven subfoveal RPE.

OS

Color

OS

Fundus Autofluorescence (FAF)

Angioid Streaks Fundus autofluorescence is useful in diagnosing an angioid streaks patient.

OD

Fundus Autofluorescence (FAF)

9

10