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poster guide peter walter, president • jonathan weissman, program chair san francisco, california dec 3-7 ascb.org/2016meeting Download the ASCB Mee...
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poster guide peter walter, president • jonathan weissman, program chair

san francisco, california dec 3-7

ascb.org/2016meeting Download the ASCB Meeting App Search for “ascb”

Save the Date cell biology of degeneration and repair in the nervous system 2017 ascb doorstep meeting december 2 • philadelphia, pa

Look for more information this Spring!

LSE

PUBLISHED BY THE AMERICAN SOCIETY FOR CELL BIOLOGY EDITORIAL PARTNER THE GENETICS SOCIETY OF AMERICA

A Peer-Reviewed Journal of Biology Education Research and Evidence-Based Biology Teaching For educators at all levels and across all life science disciplines.

Online and completely FREE. No subscription required.

No author page or color charges.

LSE emphasizes teaching innovations and evidence of their effectiveness. It publishes original research articles, essays, and features that help you apply education research to your own teaching.

www.lifescied.org

san francisco, california dec 3-7

CONTENTS Sunday Poster Session. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Monday Poster Session. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Tuesday Poster Session. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 Author Disclosures. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150

Poster Board Assignments The ASCB has assigned all poster boards with the letter “B” followed by a three or four digit number to correspond with the aisle number and poster board number: Example 1: Your poster has been assigned to “B340” B=Board; 300=Aisle in which the board is located; B140=Board number on which to place your poster. Example 2: Your poster has been assigned to “B1134” B=Board; 1100=Aisle in which the board is located; B1034=Board number on which to place your poster. Please note Board Numbers B1400-B1495 are to the right of aisle 1300.

Online Poster/Abstract Viewing From Thursday, December 1, through Wednesday, December 7, registered meeting participants will be able to visit a password-protected website to search and view abstracts, uploaded posters, and slides. This will allow participants who miss posters or presentations they were hoping to see view them, and connect with the presenter. Participants will be able to contact the presenter with any questions directly through this website. To search and view the abstracts/posters visit: http:// www.ascb.org/amabstract. A login and password was sent on to all attendees registered by November 21. This information is also provided to all meeting participants when they pick up their badge in the Registration area.

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Sunday Poster Session ASCB Learning Center, Exhibit Halls A-C Poster Set Up Saturday 5:30–6:00 pm Posters Displayed Saturday 6:00–8:00 pm Sunday 7:30 am–5:30 pm

Author Presentation Odd Boards 12:00–1:30 pm Even Boards 1:30–3:00 pm Poster Tear Down Sunday 5:30–6:00 pm

B200-B228 Science Education 1 B230-B250 Light and Electron Microscopy in New Imaging Technologies B251-B271 New Technologies for Cell Biology 1 B273-B293 Actin and Actin-Associated Proteins 1 B294-B299; B300-B311 Regulation of Actin Dynamics 1 B313-B330 Kinesins 1 B332-B347 Microtubule Dynamics and Its Regulation 1 B350-B371 Ciliary Signaling and Ciliopathies B373-B389; B400-B406 Cytokinesis 1 B407-B419 Kinetochore Assembly and Functions 1 B420-B432 Centrosome Assembly and Functions 1 B433-B454 Chromosome Organization B455-B471 Spindle Assembly 1 B473-B489; B500-B511 Cancer Therapy 1 B512-B530 Oncogenes and Tumor Suppressors 1 B531-B548 Invasion and Metastasis B549-B567 Tumor Microenvironment 1 B900-B913 Regulatory and Non-Coding RNAs B914-B920 RNA Localization, Transport, Stability, and Modification B922-B941 The Nuclear Envelope and Nuclear Pore Complexes 1 B943-B971 Endocytic Trafficking 1 B972-B989; B1000-B1001 ER and Golgi Transport B1002-B1014 Rab GTPases B1016-B1043 Cell Signaling and Polarity B1045-B1067 Neuronal Morphogenesis and the Cytoskeleton

SUNDAY

Board Numbers Session Titles

B1069-B1088 Establishing and Maintaining Organelle Structure 1 B1100-B1118 Mitochondria, Chloroplasts, and Peroxisomes 1 B1119-B1139 Lipids and Membrane Microdomains 1 B1140-B1165 Signaling from the PM/Cytoplasm to the Nucleus B1200-B1216 Signaling Scaffolds and Microdomains B1218-B1241 Mechanotransduction 1 B1242-B1247 Intermediate Filaments B1249-B1265 Cell-Cell Junctions 1 B1266-B1289 Integrins and Cell-ECM Interactions B1301-B1323 Cell Death B1324-B1343 Chaperones, Protein Folding, and Quality Control 1 B1345-B1361 Physical Approaches to Cell Biology B1362-B1368; B1400-B1404 Systems and Synthetic Biology, and Tissue Engineering B1406-B1423 Germ Cells, Gametogenesis, and Fertilization B1424-B1445 Cell-Cell Interactions in Tissue Development and Morphogenesis B1446-B1457 Cell Fate Determination 1 B1459-B1473 Prokaryotic Cell Biology B1475-B1493 Defining Therapeutic Targets and New Therapeutics 1

2016 ASCB Meeting Poster Presentation Guidelines •

Presenters should ensure their posters are placed on the appropriate poster board for the duration of their assigned poster session and viewing. Please use the number starting with “B” for your poster board.



Poster presenters should stand at their poster locations during the appropriate 90-minute time slot—odd board numbers, 12:00-1:30 pm or even board numbers, 1:30-3:00 pm (specific time slot is included in the original poster notification emails sent on November 2). If presenters have to leave early, they should post a note on their boards with contact information or stating when they will be available to answer attendee questions.



IMPORTANT! Poster presenters are solely responsible for placing and removing their poster according to the schedule provided above. If you are unable to set up your poster the evening before your session, please do so the morning of your presentation.



Poster presenters should not leave any items unattended at their poster board, including poster tubes, meeting bags, Programs, Poster Guides, personal items, etc. The ASCB is not responsible for any items left in the ASCB Learning Center.



Cameras/Photography: Cameras and all other recording devices are strictly prohibited in all session rooms, in the ASCB Learning Center, and in all poster and oral presentation sessions.

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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Board No./Presentation No.

Science Education 1 B200/P1  An Art-Driven Approach to Scientific Learning. C.L. Garr1, H. Wilson1, C. Budzinski1, V.A. Segarra1; 1Biology, High Point University, High Point, NC B201/P2 Share your expertise and enthusiasm with teachers: Organize a workshop to build cheap, homemade microscopes. B. Goldstein1, J.L. Song2, J. Gallo-Fox3, K. Yoshino4; 1Biology Department, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Department of Biological Sciences, University of Delaware, Newark, DE, 3Human Development and Family Studies, University of Delaware, Newark, DE, 4Grin City Collective and Grinnell College, Grinnell, IA B202/P3 Amgen BioTalents: a Strategic Alliance Program between Academia and Industry to Integrate Science and Engineering Students into Learning Biomanufacturing Concepts. R. Buxeda1, L. Saliceti-Piazza2; 1Department of Biology, University of Puerto Rico, Mayaguez, Mayaguez, PR, 2Department of Chemical Engineering, University of Puerto Rico, Mayaguez, Mayaguez, PR B203/P4 Analysis of student participation and impact of discussion sections in a high-enrollment upper-division genetics course. M.E. Crowder1; 1Molecular and Cellular Biology, University of California Davis, Davis, CA B204/P5 Learning Assistants in the Cell Biology Classroom. A.K. Wilson1; 1Biological Sciences, Benedictine University, Lisle, IL B205/P6 What’s in a name? The importance of student perceptions of an instructor knowing their names in a high enrollment biology classroom. K.M. Cooper1, B. Haney1, S.E. Brownell1, A. Krieg1; 1School of Life Sciences, Arizona State University, Tempe, AZ B206/P7 Coming out in class: Challenges and benefits of active learning in a biology classroom for LGBTQIA students. K.M. Cooper1, S.E. Brownell1; 1School of Life Sciences, Arizona State University, Tempe, AZ B207/P8 Show Me the Data! What You Teach is as Important as How You Teach. A.M. Campbell1, B.S. Finby2; 1Biology, Davidson College, Davidson, NC, 2High School, Charlotte Latin School, Charlotte, NC B208/P9 Infusing Metacognition during the Process of Science in an Introductory Cell and Molecular Biology Course. L.L. Dahlberg1, S.R. Lee1, B.L. Wiggins2, T. Bloom1, M. Colton1, D.S. Leaf1; 1Biology Department, Western Washington University, Bellingham, WA, 2Department of Biology, University of Washington, Seattle, WA

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Sunday Poster Session B209/P10 Three-Week Cell Biology Laboratory Exercise: Signaling Influences Subcellular Localization of TFEB-GFP. A.T. Bryant1, M. Volk1, P.S. Sickler1, S.M. Ferguson2, S. Walsh1; 1Biology, Rollins College, Winter Park, FL, 2Cell Biology, Yale University, New Haven, CT

B219/P20 Using the online macromolecular museum, case studies, and a new assessment tool to engage students in hands-on learning about the biology of sickle cell anemia. S.K. Levi1, D.J. Marcey2; 1Biology, Oakton Community College, Des Plaines, IL, 2Biology, California Lutheran University, Thousand Oaks, CA

B210/P11 Exploration of Human Pancreatic Cancer by Undergraduates as Entry Point into Next-Generation Sequence Analysis. T. Grainger1, T. Touissant1, J. Russell1, L.P. Hammonds-Odie1; 1School Of Science and Technology, Georgia Gwinnett College, Lawrenceville, GA

B220/P21 Introducing Single-Use Mammalian Cell Culture Bioreactor Technologies Into the Biomanufacturing Classroom. J. DeKloe1; 1Biotechnology, Solano College, Vacaville, CA

B211/P12 MelaNOma: An interactive online resource for improving student knowledge application in genetics. K. Yuen1, M.E. Crowder2; 1Biotechnology, University of California, Davis, Davis, CA, 2 Molecular and Cellular Biology, University of California, Davis, Davis, CA B212/P13 Teaching metric system to community college STEM students. L. Jayant1, C. Priano1; 1Science, Borough of Manhattan Community College, New York, NY B213/P14 Use of computer graphics to supplement the learning of biology protocols. F. Norflus1; 1Biology, Clayton State University, Atlanta, GA B214/P15 Using on-line text materials to improve study skills. C. Priano1, L. Jayant1; 1Science, Borough of Manhattan Community College, New York, NY B215/P16 The Breathe, Eat, Touch Project: Using an environmental health framework to augment interdisciplinary STEM learning. K.K. Bernd1, K.K. Foley2, C.D. Hauser3; 1Biology, Davidson College, Davidson, NC, 2Social Sciences and Health Policy, Wake Forest University, Winston Salem, NC, 3Chemistry, Davidson College, Davidson, NC B216/P17 Microscopy for all: Lessons from large scale Foldscope deployment around the world. M. Coyle1, M. Prakash2, J. Cybulski1, S. Bhamla2, A. Foldscope Users1; 1Foldscope Instruments, San Francisco, CA, 2Bioengineering, Stanford University, Stanford, CA B217/P18 Enhancing Student Engagement in Biology Courses: Using Tablet Technologies to Increase Learning. M. Stein1; 1Biology, California State University, Northridge, Northridge, CA B218/P19 Paperfuge: An ultra-low cost, hand-powered centrifuge inspired by the mechanics of a whirligig toy. S. Bhamla1, B. Benson*2, C. Chai*2, G. Katsikis1, A. Johri1, M. Prakash1; 1Bioengineering , Stanford University, Stanford, CA, 2 Undergraduate, Massachusetts Institute of Technology, Cambridge, MA

B221/P22 Introducing Freshman Students to Cutting Edge Scientific Research: Discovery and the Use of Hela cells. J.A. Jordan1, R. McFarlane1, P. Melvin1, J.E. Morgan1; 1Biology, Clayton State University, Morrow, GA B222/P23 Assessment of 3D molecular visualization tools in biology education. M. Volek1, R. Sarac1; 1Department of Biological Sciences, Purdue University Northwest - Hammond Campus, Hammond, IN B223/P24 Annotation of Protein-Coding in Drosophila biarmipes Contig6. J.M. Yonke1, T. Sadikot1; 1Biology, Washburn University, Topeka, KS B224/P25 Analysis and Annotation of Genomic Elements within Contig47 of Drosophila elegans. G.K. Cork1, T. Sadikot1; 1Biology Department, Washburn University, Topeka, KS B225/P26 AspirnautTM: Maximizing STEM achievement for students from diverse backgrounds by holistic, long-term commitment to scientific development. K.H. Oliver1, A.L. Fidler1,2, B.G. Hudson3,4,5,6, J. Hudson7; 1Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN, 2Biology, Tennessee State University, Nashville, TN, 3 Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, 4Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 5Medicine, Vanderbilt University Medical Center, Nashville, TN, 6Biochemistry, Vanderbilt University, Nashville, TN, 7Clinical Anesthesiology and Pediatrics, Vanderbilt University Medical Center, Nashville, TN B226/P27 A bioinformatics curriculum that teaches gene structure is associated with learning gains in beginning college students. L.V. Paliulis1, M.M. Laakso2, M.S. Santisteban3, W. Leung4, S.C. Elgin4; 1Biology Department, Bucknell University, Lewisburg, PA, 2Department of Biology, Eastern University, St. Davids, PA, 3Department of Biology, University of North Carolina at Pembroke, Pembroke, NC, 4Department of Biology, Washington University, St. Louis, MO

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B227/P28 Infusion of Bioinformatics into Biology Courses at Prairie View A&M University (PVAMU). E.C. Regisford1, D. Ritter, PhD2, L. Carson3, Q. Moore1, D. Vaden1, P. Drummond1, Y. Jung3; 1Biology, Prairie View AM University, Prairie View, TX, 2 Genome sequencing Center, Baylor College of Medicine, Houston, TX, 3Cooperative Agriculture Research Center, Prairie View AM University, Prairie View, TX

Light and Electron Microscopy in New Imaging Technologies B230/P30 Development of cryogenic correlated light electron microscopy methods to study mechanisms of intracellular trafficking and their relationships to the secretory pathway. S.D. Carter1, S.K. Mageswaran1, Z.J. Farino2, J.I. Mamede3, T.J. Hope3, J. Frank4,5, Z. Freyberg2, G.J. Jensen1,6; 1Division of Biology, California Institute of Technology, Pasadena, CA, 2Department of Psychiatry and Cell Biology, University of Pittsburgh, Pittsburgh, PA, 3School of Medicine, Northwestern University, Chicago, CA, 4 Columbia University, HHMI; Department of Biochemistry and Molecular Biophysics, New York, NY, 5Department of Biological Sciences, Columbia University, New York, NY, 6California Institute of Technology, Howard Hughes Medical Institute (HHMI), Pasadena, CA B231/P31 Disclosing novel structurefunction insights on hepatic microarchitecture through large volume correlative fluorescence and in situ block face scanning electron microscopy. G. Shami1, D. Cheng1, M. Huynh2, F. Braet1,2; 1School of Medical Sciences Discipline of Anatomy and Histology, The University of Sydney, Sydney, Australia, 2 Australian Centre for Microscopy and Microanalysis, The University of Sydney, Sydney, Australia B232/P32 FerriTag: A Genetically Encoded Inducible Tag for Correlative Light Electron Microscopy. N.I. Clarke1, S.J. Royle1; 1Centre for Mechanochemical Cell Biology, Warwick Medical School, University of Warwick, Coventry, United Kingdom

B233/P33 Development of a new software tool for multiple targeting and fully automated volume acquisitions in a Correlative Light and Electron Microscopy workflow for cell cultures. J. Serra Lleti1, A. Steyer1, N. Schieber1, M. Holtstrom2, D. Unrau2, R. Kirmse3, Y. Schwab1; 1Cell Biology and Biophysics, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, 2Fibics Inc, Ottawa, ON, 3Carl Zeiss Microscopy GmbH, Jena, Germany B234/P34 Automated High-throughput correlative light and electron microscopy. A.M. Steyer1, J.M. Serra Lleti1, N.L. Schieber1, C. Tischer1,2, V. Hilsenstein1,2, B. Neumann1,2, R. Kirmse3, D. Unrau4, J.M. Lucocq5, R. Pepperkok1,2, Y. Schwab1; 1Cellbiology Biophysics, EMBL, Heidelberg, Germany, 2Advanced Light Microscopy Facility, EMBL, Heidelberg, Germany, 3Carl Zeiss Microscopy GmbH, Jena, Germany, 4Fibics, Ottawa, Canada, 5 University of St. Andrews, Saint Andrews, United Kingdom B235/P35 Using Focused-Ion Beam Milling for Cryo-Electron Tomography to Build Molecular Atlas of a Sporangium. K. Khanna1, E. Villa1, K. Pogliano1; 1Biological Sciences, University of California, San Diego, La Jolla, CA B236/P36 Deciphering protein organization and dynamics at various scales using single-objective Selective Plane Illumination Microscope (soSPIM). R. Galland1,2, G. Grenci3, C. Butler1,2, V. Studer1,2, V. Viasnoff3,4, J. Sibarita1,2; 1Interdisciplinary Institute for Neuroscience, Université de Bordeaux, Bordeaux, France, 2IINS - UMR 5297, CNRS, Bordeaux, France, 3MechanoBiology Institute, National University of Singapore, Singapore, Singapore, 4UMI 3639, CNRS, Singapore, Singapore B237/P37 Whole-slide Imaging Approach to Assessing Allogenic Transplantation of hESC-CMs using Histological Analysis and Immunofluorescence. M. Kaze1, J. Lee1, H. Aaron1, M. Calvert2; 1Cancer Research Laboratory Molecular Imaging Center, University of California, Berkeley, CA, 2Histology and Light Microscopy Core, Gladstone Institutes, San Francisco, CA B238/P38 An optimized image analysisbased approach to quantification of liver pathology. J. Abad1, X. Liang2, M. Calvert1; 1Histology and Light Microscopy Core, Gladstone Institutes, San Francisco, CA, 2Bioengineering, UCSF, San Francisco, CA B239/P39 Imaging of three-dimensional single molecule dynamics with cellular context: Antibody trafficking and interaction with cell membrane and sorting endosomes. D. Kim1,2, S. You1,2, E.S. Ward2,3, R.J. Ober1,2; 1Biomedical Engineering, Texas AM University, College Station, TX, 2Molecular and Cellular Medicine, Texas AM Health Science Center, College Station, TX, 3Microbial Pathogenesis and Immunology, Texas AM Health Science Center, College Station, TX

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B240/P40 Visualizing enzymatic and cellular activities during tissue morphogenesis using ex vivo two-photon FRET microscopy. C. Yeh1, C. Chiu1, J. Yu2, C. Szymanski3, C. Guo2, S. Lu4, Y. Wang4, C. Chuong1; 1Pathology, University of Southern California, Los Angeles, CA, 2 Bioengineering, California Institute of Technology, Pasadena, CA, 3Thorlabs, Inc., Newton, NJ, 4Bioengineering, University of California, San Diego, San Diego, CA B241/P41 Targeting Exogenous β-Defensin to the Endolysosomal Compartment via a Biotic Guided Missile System. C.R. Morales1, F.L. Carvelli1, Y. Libin1; 1Anatomy and Cell Biology, McGill University, Montreal, QC B242/P42 4-Color Multiplexed Imaging of Sub-Diffraction Limited Cellular Structures on Inexpensive Microscopes and High Content Imaging Platforms Enabled by Expansion Microscopy. R.N. Ghosh1; 1Protein and Cell Analysis, Thermo Fisher Scientific, Pittsburgh, PA B243/P43 Identification and characterization of prion like behaviors using Amphifluoric FRET. T. Khan1, R. Halfmann1,2; 1Stowers Institute for Medical Research, Kansas City, MO, 2Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS B244/P44 A combined imaging and software approach for analyzing C. elegans embryo development. R. Christensen1, A. Bokinsky2, A. Santella3, Y. Wu1, J. Marquina4, I. Kovacevic3, A. Kumar1, E. McCreedy2, W. Mohler5, D.A. Colón-Ramos4, Z. Bao3, H. Shroff1; 1National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, 2Center for Information Technology, National Institutes of Health, Bethesda, MD, 3Developmental Biology Program, Sloan-Kettering Institute, New York, NY, 4Department of Cell Biology, Yale University, New Haven, CT, 5Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT B245/P45 Characterization of stem cells differentiation using Quantitative Phase Imaging. S. Aknoun1, S. Kawamata2, T. Yamamoto2, B. Wattellier1; 1PHASICS S.A, Saint Aubin, France, 2Foundation for Biomedical Research and Innovation, Division of Cell Therapy., Kobe, Hyogo, Japan B246/P46 Permeabilization activated reduction in fluorescence: A novel method to measure kinetics of protein interactions with intracellular structures. J.L. Hawthorne1, P.P. Singh1, C.A. Davis1, O.A. Quintero1; 1Department of Biology, University of Richmond, Richmond, VA

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SUNDAY

B228/P29 Training Module in Assuring Data Reproducibility. A.M. Medina-Lopez, B.S.1,2, H. Shinogle-Decker, B.S.1,2, N. Martinez-Rivera, Ph.D.1,2, E. Rosa-Molinar, Ph.D.1,2; 1Department of Pharmacology and Toxicology and Neuroscience Graduate Program, The University of Kansas, Lawrence, KS, 2Microscopy and Analytical Imaging Resource Core Laboratory, The University of Kansas, Lawrence, KS

Sunday Poster Session

Board No./Presentation No. B247/P47 LITE sheet microscopy: great NA, less bleaching. T. Fadero1, P.S. Maddox1; 1Biology, UNC-Chapel Hill, Chapel Hill, NC B248/P48 Spectral imaging and computational analysis reveals the systems level organelle interactome. A.M. Valm1, S. Cohen1, W.R. Legant2, J. Melunis3, U. Hershberg3,4, E. Wait5, A.R. Cohen5, M.W. Davidson6, E. Betzig2, J. LippincottSchwartz1,2; 1NICHD, NIH, Bethesda, MD, 2 Janelia Research Campus, HHMI, Ashburn, VA, 3School of Biomedical Engineering; Science and Health Systems, Drexel University, Philadelphia, PA, 4Department of Microbiology and Immunology; College of Medicine, Drexel University, Philadelphia, PA, 5Dept. of Electrical and Computer Engineering; College of Engineering, Drexel University, Philadelphia, PA, 6National High Magnetic Feild Laboratory, Florida State University, Tallahassee, FL B249/P49 Light-controlled PI3K activation mimics TRPV1 potentiation during inflammation. A. Stratiievska1, L.A. Naves2, R. Yang1, A. Pazevic1, S.E. Gordon1, M. Munari1; 1Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, WA, 2Federal University of Minas Gerais, Belo Horizonte, Brazil B250/P50 Ionic liquid application for TEM observation of liposomes. M. Wayama1, M. Konomi2, E. Nakazawa3; 1Science System Product Division, Hitachi HighTechnologies Corporation, Ibaraki, Japan, 2 Science Systems Sales Marketing Division, Hitachi High- Technologies Corporation, Tokyo, Japan, 3Product Customer Support Strategy Division, Hitachi HighTechnologies Corporation, Tokyo, Japan

New Technologies for Cell Biology 1 B251/P51 Genetically encoded fluorogenic protease reporters visualize spatiotemporal dynamics of apoptosis in vivo. X. Shu1; 1Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA B252/P52 Live single-cell laser tag. L. Binan1,2, J. Mazzafferri1, K. Choquet3,4, L. Lorenzo5, Y. De Koninck4,6, E. Affar1,2, I. Ragoussis3,7,8, C. Kleinman3,4, S. Costantino1,2; 1research center, Hopital maisonneuve rosemont, Montréal, QC, 2 Ophtalmology, Université de Montréal, Montréal, QC, 3Department of Human Genetics, University McGill, Montréal, QC, 4 Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, QC, 5 Institut Universitaire en Santé Mentale de Québec, Québec, QC, 6Université Laval, Department of Psychiatry, Québec, QC, 7 Genome Quebec Innovation Centre, Montréal, QC, 8Department of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

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Sunday Poster Session B253/P53 The physical organization of the human induced pluripotent stem cell: developing assays for image-based integration of intracellular structures. S.M. Rafelski1; 1Allen Institute for Cell Science, Seattle, WA B254/P54 Optogenetic modulation of Raf and AKT activity in preconditioning and postconditioning PC12 cells against oxidative stress. Q. Ong1, K. Zhang2, S. Guo1, L. Duan1, E. Collier1, B. Cui1; 1Department of Chemistry, Stanford University, Stanford, CA, 2Department of Biochemistry, University of Illinois, UrbanaChampaign, Urbana, IL B255/P55 Highly localized, rapid and reversible optogenetic regulation of protein activity in subcellular compartments. L. Benedetti1,2,3,4, M. Messa1,2,3,4, E.B. Kromann2,5, H. Wheeler1,2,3,4, J. Bewersdorf2,5,6,7, P. De Camilli1,2,3,4,6; 1Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 2Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 3Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT, 4Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 5Department of Biomedical Engineering, Yale University, New Haven, CT, 6Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, 7Nanobiology Institute, Yale University, New Haven, CT B256/P56 New applications for fluorescent lipids as metabolic tracers in the larval zebrafish. V.H. QuinlivanRepasi1,2, M.H. Wilson1, J. Ruzicka3, S.A. Farber1,2; 1Embryology, Carnegie Institution for Science, Baltimore, MD, 2Biology, The Johns Hopkins University, Baltimore, MD, 3 Thermo Scientific, Somerset, NJ B257/P57 Normalization of Functional Cellular Metabolic Data using Cell Counting. Y. Kam1, P.G. Held2, T. Cumbo1, P. Swain1, J.E. Clayton2, P. Banks2, B.P. Dranka1; 1Agilent Technologies, Lexington, MA, 2BioTek Instruments, Winooski, VT B258/P58 Antibodypedia – The Wiki of Antibodies. T.L. Alm1, K. von Feilitzen1, M. Uhlén1; 1School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden B259/P59 Genomic integrity of human induced pluripotent stem cells after CRISPR/Cas-9 fluorescent tag knock-in. R. Gunawardane1; 1Allen Institute for Cell Science, Seattle, WA

B260/P60 Immortal fetal liver macrophages as a new model for studying macrophage function. M.I. Lebedev1,2, P. Swaminathan1,3, J.G. Kerkvliet1,4, L.M. Martinez1,4, X. Ge1,5, A. Fennell1,3, A.D. Hoppe1,4; 1BioSNTR, Brookings, SD, 2 Biology and Microbiology, South Dakota State University, Brookings, SD, 3Agronomy, Horticulture, and Plant Science, South Dakota State University, Brookings, SD, 4 Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 5 Mathematics and Statistics, South Dakota State University, Brookings, SD B261/P61 Dynamics of Translation of Single mRNA Molecules In Vivo. X. Yan1, T.A. Hoek2, R.D. Vale1, M.E. Tanenbaum2; 1Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 2Hubrecht Institute, Utrecht, Netherlands B262/P62 Single-cell quantification of ATP concentrations inside mammalian cells by an improved fluorescent ATP indicator. H. Yaginuma1, Y. Okada1; 1QBiC, RIKEN, Suita, Japan B263/P63 Multiplexing strategies using confocal microscopy. V. Ibarra1, J. Webster2, M.S. Johnson Sagolla2, H. Koeppen2, C.M. Chalouni2; 1Illinois Institute of technology, Chicago, IL, 2Pathology labs, Genentech, South San Francisco, CA B264/P64 Analysis of cellular mechanisms that may regulate the thymus developmental program using CLARITY clearing of whole organs. E.J. Baker1, N.R. Manley1, B.G. Condie1, E.R. Richie2; 1Department of Genetics, University of Georgia, Athens, GA, 2Department of Carcinogenesis, University of Texas, M.D. Anderson Cancer Center, Science Park Research Division, Smithville, TX B265/P65 Real-Time Multi-Colony Observation at the Single-Cell Level with On-Demand Perturbation via a Microfluidic Examination Trap. J. Helton1, R. Kannan1, V. Yeh1; 1MilliporeSigma, Hayward, CA B266/P66 Comparative assessment of fluorescent proteins for in vivo imaging in an animal model system. J.K. Heppert1, D. Dickinson1, A.M. Pani1, C.D. Higgins1, B. Goldstein1; 1Biology, The University of North Carolina at Chapel Hill, Chapel, United States B267/P67 Deep learning automates the quantitative analysis of individual cells in live-cell imaging experiments. D. Van Valen1, T. Kudo1, K. Lane1, D. Macklin1, N. Quach1, M. DeFelice1, I. Maayan1, Y. Tanouchi1, E. Ashley2,3, M.W. Covert1; 1Bioengineering, Stanford University, Stanford, CA, 2Cardiovascular Medicine, Stanford University, Stanford, CA, 3 Genetics, Stanford University, Stanford, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B268/P68 Live 5D hyper-spectral fluorescence imaging of developing zebrafish. F. Cutrale1, V. Trivedi2, L.A. Trinh1, C. Chiu3, J.M. Choi1, M.S. Artiga1, S.E. Fraser1; 1Translational Imaging Center, Molecular and Computational Biology, University of Southern California, Los Angeles, CA, 2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 3Lawrence J. Ellison Institute for Transformative Medicine, Center for Applied Molecular Medicine, University of Southern California, Los Angeles, CA

B270/P70 Optogenetics Tools for Noninvasive Manipulation and Observation of Excitable Cells in the Embryonic Chick. S. Fromherz1, J. Whitaker2, A. Frassato2, L. DeRossett2, A.A. Sharp2,3; 1Biology, Saginaw Valley State University, University Center, MI, 2 Physiology, Southern Illinois University, Carbondale, IL, 3Anatomy, Southern Illinois University, Carbondale, IL B271/P71 Combined chemical and optical control of T-cell signaling using a synthetic antigen receptor. M.J. Harris1, J.R. James1; 1Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Actin and Actin-Associated Proteins 1 B273/P72 Phosphorylation of Sharpin acts as a molecular switch to control Linear Ubiquitination Assembly Complex (LUBAC) and Arp2/3 function. U. Butt1,2, M.H. Khan1,2, g. jacquemet1,3, M.J. Humphries3, J. Pouwels1; 1Centre for Biotechnology, University of Turku, Turku, Finland, 2Turku Doctoral Programme of Molecular Medicine, University of Turku, Turku, Finland, 3Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

B274/P73 The Sharpin interactome reveals a role for Sharpin in lamellipodium formation through the Arp2/3 complex. M.H. Khan1, S. Salomaa1, g. jacquemet1,2, T. Deguchi1, e. kremneva3, P. Lappalainen3, M.J. Humphries2; 1Turku Centre for Biotechnology, University of Turku, Turku, Finland, 2Faculty of Life Sciences, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester, United Kingdom, 3Institute of Biotechnology, University of Helsinki, Helsinki, Finland B275/P74 Deficiency of Ubiquitin-like Protein Ubl4A Impairs Cell Migration. H. Zhang1, Y. Zhao1, R. Bonomo1, A. Mañas1, J. Xiang1; 1Department of Biology, Illinois Institute of Technology, Chicago, IL B276/P75 Loss of a Novel Branched Actin Checkpoint in Cancer Cells. N. Molinie1, S.N. Rubtsova1, A. Gautreau1; 1CNRS UMR7654, Ecole Polytechnique, Palaiseau, France B277/P76 Unraveling the role Arp2/3 complex subunit 1b during spermatogenesis: An in vivo RNAi approach in adult rat. A.V. Kumar1, K.D. Dumasia1, N.H. Balasinor1; 1Dept. of Neuroendocrinology, National Institute for Research in Reproductive Health, Mumbai, India B278/P77 Functional involvement of actin-nucleating factor, Arp2/3 complex, in regulation of MTOC-TMA assembly during Xenopus oocyte maturation. Y. Yamagishi1,2, H. Abe2; 1JSPS, Tokyo, Japan, 2 Nanobiol., Grad. Sch. of Advanced Integration Sci., Chiba Univ, Chiba, Japan B279/P78 ACD-crosslinked actin oligomers target WH2-domain proteins to disrupt the actin cytoskeleton. D.B. Heisler1,2, B. Williams2, K. Shafer2, E. Kudryashova2, D.S. Kudryashov1,2; 1Ohio State Biochemistry Program, Ohio State University, Columbus, OH, 2Department of Chemistry and Biochemistry, Ohio State University, Columbus, OH B280/P79 Conditional knock out of N-WASP expression in keratinocytes caused epidermal hyperplasia in mice. P. Kalailingam1, H. Tan1, T. Thanabalu1; 1School of Biological Sciences, Nanyang Technological University, Singapore, Singapore B281/P80 Characterization of CARMILGAP, a Dictyostelium CARMIL isoform harboring a GTPase activating domain for Rac. G. Jung1, J.A. Hammer1; 1CBPC, NHLBI, NIH, Bethesda, MD B282/P81 Exploring a cellular inhibitor which links between the formin INF2 and human diseases. M. A1; 1Biochemistry, Dartmouth College, Hanover, NH

B284/P83 Interplay between filopodia and focal adhesions through the formin FMNL3. L.E. Young1, E.G. Heimsath2, H.N. Higgs1; 1Biochemistry, Dartmouth College, Hanover, NH, 2Cell Biology and Physiology, UNC, Chapel Hill, NC B285/P84 Ena/VASP- and Formin-mediated filopodia formation is facilitated by Fascin. C. Suarez1, J.D. Winkelman2, A.J. Harker3, A.N. Morganthaler1, D.R. Kovar1,3; 1Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL, 2Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 3Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL B286/P85 FMNL formins are required for lamellipodial force generation. F. Kage1,2, M. Winterhoff3, V. Haas1,2, J.M. Müller4, T. Thalheim5, A. Freise2, S. Bruehmann3, J. Kollasser1, J. Block1, G. Dimchev1,2, M. Geyer6, C.H. Brakebusch7, T.E. Stradal1, M. Carlier8, M. Sixt4, J. Käs5, J. Faix3, K. Rottner1,2; 1Molecular Cell Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany, 2Molecular Cell Biology, Technical University Braunschweig, Braunschweig, Germany, 3Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany, 4Institute of Science and Technology, Klosterneuburg, Austria, 5Institut für experimentelle Physik, Leipzig University, Leipzig, Germany, 6 Institute of Innate Immunity, University of Bonn, Bonn, Germany, 7BRIC, University of Copenhagen, Copenhagen, Germany, 8 Cytoskeleton Dynamics and Motility, National Centre for Scientific Research, Paris, France B287/P86 Single molecule imaging reveals that Spire and the formin Capu interact at barbed ends to antagonize capping protein and promote actin filament growth. R. Jaiswal1, C.L. Vizcarra2, M.E. Quinlan2, B.L. Goode1; 1Biology, Brandeis University, Waltham, MA, 2Chemistry and Biochemistry and Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA B288/P87 Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse. S. Murugesan1, J. Hong1, J. Yi1, D. Li2, J. Beach1, L. Shao2, X. Wu1, E. Betzig2, J.A. Hammer1; 1Cell Biology and Physiology Center, The National Institutes of Health, Bethesda, MD, 2HHMI, Janelia Research Campus, Ashburn, VA B289/P88 Dissecting the roles of anillinDIAPH3 interaction in regulating actin cytoskeleton. A. Chen1, A.R. Wilde1; 1Biochemistry, University of Toronto, Toronto, ON

B283/P82 Characterization of a deafnessassociated mutant of human DIAPH1. T. Jabeen1, C.L. Vizcarra1; 1Chemistry, Barnard College, New York, NY

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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SUNDAY

B269/P69 Engineering a Light Activated Caspase to use Temporally and Locally in vivo. A.D. Smart1,2,3,4,5, N.D. Thomsen2,3, R.A. Pache6,7, T. Kortemme6,7, G.W. Davis4,5, J.A. Wells2,3; 1Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA, 2 Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 3Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 4Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, 5Kavli Institute for Fundamental Neuroscience, University of California San Francisco, San Francisco, CA, 6California Institute for Quantitative Biomedical Research, University of California San Francisco, San Francisco, CA, 7Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA

Sunday Poster Session

Board No./Presentation No. B290/P89 A population of the formin FMNL3 exists as endosomally-associated intracellular particles. L.E. McCormick1, L.E. Young1, H.N. Higgs1; 1Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH B291/P90 Adenomatous polyposis coli (APC)-mediated actin nucleation is required for directed cell migration. M. Angeles Juanes-Ortiz1, R. Jaiswal1, A. Badache2, B.L. Goode1; 1Biology, Brandeis University, Waltham, MA, 2Centre de Recherche en Cancerologie de Marseille, Institut Paoli-Calmettes, MARSEILLE, France B292/P91 An alternative splice isoform of the formin FMNL1 contributes to cancer cell adhesion and migration independent of the actin-binding ability of the FH2 domain. E.W. Miller1, S.D. Blystone1; 1Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY B293/P92 Modulation of actin architecture by formins regulates adherens junction maturation. B. Hissa1, R.M. Harmon1, Y.M. Beckham1, M.L. Gardel1; 1Physics Department, University of Chicago, Chicago, IL

Regulation of Actin Dynamics 1 B294/P93 Dissecting the role of RhoA, -B and -C during host-pathogen interaction. J. Halfen1, J. Kollasser1, L. Gröbe2, P. Hagendorff3, R. Geffers3, A. Steffen1, C.H. Brakebusch4, K. Rottner5, T.E. Stradal1; 1Cell Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany, 2Flow Cytometry and Cell Sorting, Helmholtz Centre for Infection Research, Braunschweig, Germany, 3Genome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany, 4 Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark, 5Molecular Cell Biology, Technical University Braunschweig, Braunschweig, Germany B295/P94 Reciprocal activities of RhoA and Rac2/Cdc42 regulate macrophage actin polymerization during catabolism of aggregated LDL. R.K. Singh1, I. Grosheva1, A.M. Brumfield1, F.R. Maxfield1; 1Department of Biochemistry, Weill Cornell Medical College, New York, NY B296/P95 Identification of cancerassociated mutations in p190RhoGAP affecting its localization and function. F. Binamé1,2, A. Bidaud-Meynard1,2, L. Magnan1,2, L. Piquet1,2, B. Montibus1,2, A. Chabadel3, F. Saltel1,2, V. Lagrée1,2, V. Moreau1,2; 1Univ. Bordeaux, Bordeaux, France, 2INSERM U1053, Bordeaux, France, 3Aix-Marseille Université, Marseille, France

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Sunday Poster Session B297/P96 IQGAP1 orchestrates multivesicular endosomal dynamics in epithelial cells. V. Schweikhard1, E.B. Samson1, D. Tsao1, J. Zimak1, T. McLaughlin1, J.S. Orange2, E.M. Mace2, M.R. Diehl1; 1Bioengineering, Rice University, Houston, TX, 2Center for Human Immunobiology, Baylor College of Medicine Texas Children’s Hospital, Houston, TX B298/P97 Vav2 associates with ERBB by means of its SH2 domain but requires additional signaling from the Insulinlike Growth Factor I receptor to drive migration in cancer cells: Analysis of Vav2 interactome. J. McKinzie1, I. Prabakaran1, T. Beer2, H. Tang2, A. Lim1, M.A. Guvakova1; 1Surgery, University of Pennsylvania, Philadelphia, PA, 2Proteomics and Metobolomics Facility, The Wistar Institute, Philadelphia, PA B299/P98 Mechanisms of cell-intrinsic adaptation in response to Adams-Oliver Syndrome gene DOCK6 disruption. B. Cerikan1, R. Shaheen2, G.P. Colo3, C. Gläßer1, S. Hata1, K. Knobeloch4, F.S. Alkuraya2, R. Fässler3, E. Schiebel1; 1ZMBH, University of Heidelberg, Heidelberg, Germany, 2Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, 3Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany, 4Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany B300/P99 Evidence that an INF2-related formin limits the accumulation of actin filaments in epithelial cells of C. elegans. A. Hegsted1, F. Wright2, S. Votra1, D.W. Pruyne1; 1Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY, 2Pharmacology, SUNY Upstate Medical University, Syracuse, NY B301/P100 Mechanosensitive inhibition of formin facilitates contractile ring assembly in fission yeast. D. Zimmermann1, K.E. Homa1, G.M. Hocky2, L.W. Pollard3, G.A. Voth2, M.J. Lord3, K.M. Trybus3, D.R. Kovar1,4; 1Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 2Department of Chemistry, James Franck Inst. for Biophysical Dynamics and Computation Inst., University of Chicago, Chicago, IL, 3Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, 4Biochemistry and Molecular Biology, University of Chicago, Chicago, IL B302/P101 Drosophila Formin Homology Domain-Containing Protein (FHOD) nucleates and bundles actin filaments but does not affect elongation. A.A. Patel1, Z.A. Oztug Durer2,3, A.P. van Loon1, M.E. Quinlan2,4; 1Molecular Biology Interdepartmental Doctoral Program, University of California, Los Angeles, Los Angeles, CA, 2Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 3Department of Medical Biochemistry, Acibadem University School of Medicine, Istanbul, Turkey, 4 Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA

B303/P102 Biochemical characterization of murine Delphilin, a neuron specific formin. W.T. Silkworth1, K.L. Kunes1, A. Kim1, D. Park1, M.E. Quinlan1,2; 1Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 2 Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA B304/P103 β2 integrins mediate the formation of a focal adhesion-like cytoskeleton and signaling platform during phagocytosis. V. Jaumouillé1, T. Liu2, E. Betzig2, C.M. Waterman1; 1National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 2Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA B305/P104 Cofilin drives rapid turnover to fluidize entangled F-actin solutions. P.M. McCall1,2, D.R. Kovar3,4, M.L. Gardel1,2,5; 1Physics, University of Chicago, Chicago, IL, 2James Franck Institute, University of Chicago, Chicago, IL, 3Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 4 Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, 5Institute for Biophysical Dynamics, University of Chicago, Chicago, IL B306/P105 WASP maintains cell polarity by preventing aberrant accumulation of active Rac. C. Amato1, A.J. Davidson2, P.A. Thomason1, S. Barratt1, S. Ismail1, R.H. Insall1; 1CRUK Beatson Institute, Glasgow, United Kingdom, 2University of Bristol, Bristol, United Kingdom B307/P106 Calcium Signaling Induces Arp2/3-mediated Actin Polymerization in the Nucleus to Trigger a Gene Expression Profile Required for T Lymphocyte Activation. N. Tsopoulidis1, C. Baarlink2, R. Grosse2, O.T. Fackler1; 1Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, Heidelberg, Germany, 2Institute of Pharmacology, Biochemical-Pharmacological Center, University of Marburg, Marburg, Germany B308/P107 Coordination of Arp2/3 and VASP in the dual protrusion revealed by machine learning analysis of protrusion velocities. C. Wang1, H. Choi1, S. Kim1, K. Lee1; 1Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA B309/P108 ADF/Cofilin are necessary to establish, shape, and maintain auditory stereocilia bundles. J.K. McGrath1, B.J. Perrin1; 1Biology, Indiana University - Purdue University Indianapolis, Indianapolis, IN B310/P109 Myosin-based contraction and oriented filament elongation synergize to build and maintain highly aligned filament arrays during cytokinesis in C. elegans. Y. Li1, W.M. Mcfadden1, E.M. Munro1; 1BSD, the University of Chicago, Chicago, IL B311/P110 Spatiotemporal regulation of Arp2/3 complex-mediated actin filament assembly by SH3 domain- and PRMmediated protein interactions. Y. Sun1, D.G. Drubin1; 1MCB, University of California at Berkeley, Berkeley, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Kinesins 1 B313/P111 Polarized dendritic transport in neurons relies on kinesin-1 autoinhibition. M.T. Kelliher1,2, Y. Yue3, A. Ng1, A.A. Hoskins1, K.J. Verhey3, J. Wildonger1; 1Biochemistry, University of Wisconsin-Madison, Madison, WI, 2 Integrated Program in Biochemistry, University of Wisconsin-Madison, Madison, WI, 3Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI

B315/P113 Kif1B interacts with KBP to promote axon elongation by localizing a microtubule regulator to growth cones. C. Drerup1, S. Lusk1, A. Nechiporuk1; 1Cell, Developmental Cancer Biology, Oregon Health Science University, Portland, OR B316/P114 The molecular mechanism that regulates a neuronal kinesin UNC-104/KIF1A in synaptic formation. S. Niwa1, D. Lipton2, S.Y. Lu2, L. Tao2, M. Morikawa3, C. Zhao4, H. Lu4, N. Hirokawa3, K. Shen2; 1Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan, 2Department of Biology, Stanford University, Stanford, CA, 3 Department of Cell Biology, University of Tokyo, Tokyo, Japan, 4School of Chemical Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA B317/P115 Phosphorylation of KLC1 regulates the velocity of APP transport through JIP1 interaction. K. Chiba1, K. Chien2, R.J. Davis3, Y. Okada4,5, A.C. Nairn6, M. Kinjo7, R. Wang2, T. Suzuki1; 1Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, 2 Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 3Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, 4Laboratory for Cell Polarity Regulation, RIKEN Quantitative Biology Center, Suita, Japan, 5Department of Physics, Graduate School of Science, The University of Tokyo, Tokyo, Japan, 6Department of Psychiatry, Yale University School of Medicine, New Haven, CT, 7Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan

B318/P116 Multiple phosphorylations of Alcadeinα regulates interaction with kinesin-1. Y. Sobu1, S. Hata1, T. Suzuki1; 1Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan B319/P117 A systematic approach to characterize the vesicles moved by different kinesins. R. Yang1, Z. Bostick1, J. Luisi1, G. Banker1, M. Bentley1; 1Jungers Center for Neurosciences Research, Oregon Health Science University, Portland, OR B320/P118 The fast reattachment rate of kinesin-2 enhances its performance in multi-motor transport. Q. Feng1, W.O. Hancock1,2; 1Molecular Cellular Integrative Biological Sciences, Pennsylvania State University, State College, PA, 2Biomedical Engineering, Pennsylvania State University, State College, PA B321/P119 The regulation of KIF3 motor complex by phosphorylation. K. Chen1; 1School of Biological Sciences, Nanyang Technological University, Singapore, Singapore B322/P120 Microtubule Gliding Powered by Membrane-bound Kinesin-1 Motors. R. Jiang1, S. Park2, G. Chen2, S. Majd3, W.O. Hancock1,2; 1Intercollege Program in Physiology, The Pennsylvania State University, University Park, PA, 2 Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 3Department of Biomedical Engineering, University of Houston, Houston, TX B323/P121 Effect of membrane coupling on multiple-kinesin transport. J. Lopes1, D.E. Chapman2, L. Hirst1, J. Xu1; 1Physics, UC Merced, Merced, CA, 2Developmental and Cell Biology, UC Irvine, Irvine, CA B324/P122 Microtubule Defects Influence Kinesin-Based Transport In Vitro. W.H. Liang1, Q. Li1, S.J. King2, J. Xu1; 1Physics, UC Merced, Merced, CA, 2Burnett School of Biomedical Sciences, U Central Florida, Orlando, FL B325/P123 Quantitative Determination of the Probability of Multiple-Motor Transport in Bead-Based Assays. Q. Li1, S.J. King2, A. Gopinathan1, J. Xu1; 1Physics, University of California, Merced, CA, 2 Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL B326/P124 Cargo transport by teams of Kinesin-1 motors is slowed down by macromolecular crowding. G. Nettesheim1, G. Jaffe1, S.J. King2, G.T. Shubeita1,3; 1Physics, The University of Texas at Austin, Austin, TX, 2Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 3Physics, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B327/P125 Interrogating The Effect of Single Motor Mutations On Emergent Transport Properties For Molecular Motor Ensembles: An Exact Approach. S. Bhaban1, D. Materassi2, M. Li3, T.S. Hays3, M.V. Salapaka1; 1Electrical Engineering, University of Minnesota, Minneapolis, MN, 2 Electrical Engineering Computer Science, University of Tennessee, Knoxville, TN, 3 Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN B328/P126 Ciliary and cytoplasmic kinesin-2 motors take hand-over-hand steps to support unexpectedly long run lengths on axonemes and microtubules. G. Merck1, W. Stepp1, Z. Ökten1; 1 PhysikDepartment E22, Technische Universität München, Garching, Germany B329/P127 Cooperative Transport by Populations of Fast and Slow Kinesins Reveals Important Familydependent Motor Characteristics. G. Arpag1,2, S.R. Norris2, K.J. Verhey3, W.O. Hancock4, E. Tuzel1; 1Physics, Worcester Polytechnic Institute, Worcester, MA, 2Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 3Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 4Biomedical Engineering, Pennsylvania State University, University Park, PA B330/P128 The unusual character of active diffusion along cytoskeletal filaments. M. Vershinin1,2, O. Osunbayo2; 1Physics Astronomy, University of Utah, Salt Lake City, UT, 2Biology, University of Utah, Salt Lake City, UT

Microtubule Dynamics and Its Regulation 1 B332/P129 Self-repair promotes microtubule rescue. C. Aumeier1, L. Schaedel1, J. Gaillard1, K. John2, L. Blanchoin1, M. Théry3; 1CEA/INRA/CNRS/ Université Grenoble-Alpes, CytoMorpho Lab, Biosciences Biotechnology Institute of Grenoble, Grenoble, France, 2CNRS / Université Grenoble-Alpes, Laboratoire Interdisciplinaire de Physique, SaintMartin-d, France, 3INSERM/Université Paris Diderot, CytoMorpho Lab, Hopital Saint Louis, Institut Universitaire d’Hematologie, Paris, France B333/P130 Mechanistic analysis of microtubule dynamics and mechanochemistry. E.A. Geyer1, J.W. Driver2, M. Bailey2, C.L. Asbury2, L.M. Rice1; 1Biochemistry and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 2Biophysics and Physiology, University of Washington, Seattle, WA

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SUNDAY

B314/P112 The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function. Y. Tanaka1, S. Niwa1, M. Dong1, A. Farkhondeh1, L. Wang1, R. Zhou1, N. Hirokawa1,2; 1Dept Cell Biol & Anat, Univ Tokyo Grad Sch Med, Tokyo, Japan, 2Center of Excellence in Genome Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia

Sunday Poster Session

Board No./Presentation No. B334/P131 Carboxy-terminal tail of β-tubulin regulates dynamic instability. C.P. Fees1, J.K. Moore1; 1Cell and Development, University of Colorado Denver Anschutz Medical Campus, Aurora, CO B335/P132 Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine. B.T. Castle1, S.M. McCubbin2, L.S. Prahl1, J.N. Bernens1, D.S. Sept2, D.J. Odde1; 1Biomedical Engineering, University of Minnesota, Minneapolis, MN, 2Biomedical Engineering, University of Michigan, Ann Arbor, MI B336/P133 Dose-dependent effect of microtubule inhibitors on microtubule dynamics: quantitative analysis. A.S. Serikbaeva1, S. Kauanova1, A. Tvorogova2, I.A. Vorobjev1,2; 1School of Science and Technology, Department of Biology, Nazarbayev University, Astana, Kazakhstan, 2 Department of Cell Biology and Histology, Faculty of Biology, A.N. Belozersky Institute of Physico-Chemical Biology, Moscow, Russia B337/P134 Mitotic arrest induced by anti-microtubule drugs is poorly related to inhibition of cell growth in normal and cancer cells. A. Kakpenova1, S. Bekbayev2, S. Kauanova1, A. Balabiyev1, A. Tvorogova3, I.A. Vorobjev1,2,3; 1National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan, 2School of Science and Technology, Nazarbayev University, Astana, Kazakhstan, 3Faculty of Biology, M.V. Lomonosov Moscow State University, Department of Cell Biology and Histology, A.N. Belozersky Institute of PhysicoChemical Biology, Moscow, Russia B338/P135 Reconstitution of three-phase microtubule polymerisation dynamics. T. Moriwaki1, G. Goshima1; 1Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Japan B339/P136 CLASP1 regulates EC branch formation and directed cell migration by promoting slow MT growth dynamics. N.M. Myer1, K.A. Myers1; 1Biological Sciences, University of the Sciences in Philadelphia, Philadelphia, PA B340/P137 TACC3, a microtubule plus-end tracking protein, affects neural crest migration in embryonic development. E.A. Bearce1, E.L. Rutherford1, A. Francl1, L. Carandang1, M. Evans1, L. Lowery1; 1Biology, Boston College, Chestnut Hill, MA B341/P138 The unique and collective functions of TACC family members in regulating microtubule plus-end dynamics in vivo. E.L. Rutherford1, L. Carandang1, P. Ebbert1, M. Evans1, C. Lucaj1, L. Lowery1; 1Department of Biology, Boston College, Chestnut Hill, MA

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Sunday Poster Session B342/P139 Centriolar CPAP/SAS-4 imparts slow processive microtubule growth. A.B. Aher1, A. Sharma2, N. Brown3, D. Frey2, E. Katrukha1, R. Jaussi2, I. Grigoriev1, M. Croisier4, R. Kammerer2, A. Akhmanova1, P. Gonczy3, M. Steinmetz2; 1Faculty of Science, Utrecht University, Cell Biology, Utrecht, Netherlands, 2Department of Biology and Chemistry, Paul Scherrer Institut, Laboratory of Biomolecular Research, Villigen, Switzerland, 3School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Swiss Institute for Experimental Cancer Research (ISREC), Lausanne, Switzerland, 4 Swiss Federal Institute of Technology (EPFL), Bio-EM Facility, Lausanne, Switzerland B343/P140 Profilin directly regulates microtubule dynamics and microtubuleactin crosstalk using residues mutated in ALS. J.L. Henty-Ridilla1, B.L. Goode1; 1Biological Sciences, Brandeis University, Waltham, MA B344/P141 The effect of cypin on microtubule dynamics in live Xenopus cells. J.T. Bowers1, L. Hayrapetian1, L. Lowery1; 1Department of Biology, Boston College, Chestnut Hill, MA B345/P142 Mechanistic insight into the powerful microtubule destabilizing activity of UNC-45A: a novel microtubuleassociated protein. A. Moonyham1, C. Coombes1, Y. Iizuka1, M. McClellan1, M.K. Gardner1, M. Bazzaro1; 1Masonic Cancer Center, University of Minnesota, Minneapolis, MN B346/P143 Regulation of microtubules by dynamin-2 in HeLa cells. M. Nakagushi1, K. Hamao1; 1Department of Biological Science, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, Japan B347/P144 A novel function of kinesin-1: changing microtubule conformation that accelerates successive kinesin binding. T. Shima1,2, Y. Okada1,2; 1RIKEN QBiC, Osaka, Japan, 2Graduate School of Science, The University of Tokyo, Tokyo, Japan

Ciliary Signaling and Ciliopathies B350/P146 IFT20 collaborates with RING finger E3 ubiquitin ligases c-Cbl and Cbl-b to control and modulate PDGFRα signaling. F. Schmid1, K.B. Schou1, M.J. Vilhelm1, L. Breslin2, L.A. Larsen3, J.S. Andersen3, L.B. Pedersen1, S.T. Christensen1; 1Department of Biology, University of Copenhagen, Copenhagen, Denmark, 2Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark, 3Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark B351/P147 A Novel Role of Sonic Hedgehog Signaling in Differentiated Human Airway Epithelia. S. Mao1,2,3, A. Shah4, L.R. Reznikov5, T. Moninger2,3, L.S. Ostedgaard2,3, M.J. Welsh1,2,3; 1Molecular physiology and biophysics, University of Iowa, Iowa City, IA, 2Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 3Howard Hughes Medical Institute, Iowa City, IA, 4University of Chicago, Chicago, IA, 5Department of Physiological Sciences, University of Florida, Iowa City, IA B352/P148 Ciliary Hedgehog signaling controls fatty degeneration of skeletal muscle. D. Kopinke1, J.F. Reiter1; 1Biochemistry, UCSF, San Francisco, CA B353/P149 Molecular mechanisms to manipulate calcium/ cAMP dynamics in initiating osteocyte mechanotransduction. E.R. Moore1, Y. Yang1, Y. Zhu1, C.R. Jacobs1; 1Biomedical Engineering, Columbia University, New York, NY B354/P150 Intraciliary calcium oscillations initiate vertebrate left-right asymmetry. S. Yuan1, L. Zhao2, M. Brueckner1,2, Z. Sun2; 1Pediatrics, Yale University School of Medicine, New Haven, CT, 2Genetics, Yale University School of Medicine, New Haven, CT B355/P151 The screen and identity of CHD(congenital heart disease) candidate genes. J. Li1, R. Hu1, H. Tang1, H. Wang1, Y. Cao1; 1School of Life Sciences and Technology, Tongji University, Shanghai, China B356/P152 Evolutionary proteomics uncovers conserved ciliary signaling pathways involved in human ciliopathies. M. Abdedin Sigg1, T. Menchen2, V.L. Jensen2, J. Johnson1, N. Krogan1, F. Rentzsch3, M.R. Leroux2, H. Omran4, J.F. Reiter1; 1UCSF, San Francisco, CA, 2 Simon Fraser University, Burnaby, BC, 3 Sars International Centre for Marine Molecular Biology, Bergen, Norway, 4 Universitätsklinikum Münster, Münster, Germany

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Board No./Presentation No. B357/P153 A calmodulin gene is required for acid-induced deflagellation in Chlamydomonas reinhardtii. Q. Wu1, Y. Liang1, J. Pan1,2; 1MOE Key Laboratory of Protein Sciences, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China, 2Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China

B359/P155 Centrosome Amplification Disrupts Renal Development and Causes Cystic Kidney Disease. K. Shim1, L. Dionne1, M. Hoshi1, V. Marthiens2, A. Knoten1, R. Basto2, S. Jain1, M.R. Mahjoub1; 1Dept of Medicine (Nephrology), Washington University, St Louis, MO, 2 Institue Curie, Paris, France B360/P156 CRISPR-Cas9 mediated knockout of ciliary genes to study polycystic kidney disease. S.J. Jerman1, Z. Sun1; 1Genetics, Yale University School of Medicine, New Haven, CT B361/P157 Smyd2 is a novel regulator of ADPKD, ARPKD and Joubert Syndrome as well as ciliopathy. X. Li1, L.X. Fan1, J.X. Zhou1, J.P. Calvet1, X. Li1; 1Kidney Institute, University of Kansas Medical Center, Kansas City, KS B362/P158 Assessing the Impact of Primary Cilia loss on Epithelial Phenotype and Function in a Human Renal Proximal Tubular Epithelial cell line. M. Higgins1, T. McMorrow1; 1Conway Institute, University College Dublin, Dublin, Republic of Ireland B363/P159 Effects of conditional disruption of primary cilia in POMC expressing cells on feeding behavior and body weight. S.E. Engle1, L. Whitehouse1, R. Bansal1, N.F. Berbari1; 1Department of Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN B364/P160 Genome-wide siRNA screening identifies deubiquitinase as a therapeutic candidate for the ciliopathies. I. Tsai1,2, N. Katsanis1,2; 1Department of Cell Biology, Duke University, Durham, NC, 2Center for Human Disease Modeling, Duke University, Durham, NC B365/P161 Identifying Pathways that Regulate Flagellar Assembly. B. Jack1,2, P. Avasthi3,4; 1Chemistry, Rockhurst University, Kansas City, MO, 2K-INBRE Summer Scholarship Program, Kansas University Medical Center, Kansas City, KS, 3Anatomy and Cell Biology, Kansas University Medical Center, Kansas City, KS, 4Ophthalmology, Kansas University Medical Center, Kansas City, KS

B366/P162 Investigating the role of ERKmediated actin phosphorylation in ciliary dynamics. S. Dutta1, P. Avasthi1,2; 1Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, 2 Ophthalmology, University of Kansas Medical Center, Kansas City, KS B367/P163 Promotion of molecular assembly by a flagellar nucleoside diphosphate kinase. X. Zhu1, Y. Maizy1, Y. Liu1, P. Yang1; 1Department of Biological Sciences, Marquette University, Milwaukee, WI B368/P164 Application of CRISPR/Cas9Based Functional Genomic Screening to Cilium-Dependent Hedgehog Signaling. D.K. Breslow1,2, S. Hoogendoorn3, A.R. Kopp2, D.W. Morgens4, J.K. Chen3,5, M.V. Nachury2; 1Molecular, Cellular Developmental Biology, Yale University, New Haven, CT, 2Molecular Cellular Physiology, Stanford University, Stanford, CA, 3Chemical Systems Biology, Stanford University, Stanford, CA, 4Genetics, Stanford University, Stanford, CA, 5Developmental Biology, Stanford University, Stanford, CA B369/P165 Mechanisms of signaldependent exit from cilia. F. Ye1, A.R. Nager1, M.V. Nachury1; 1Molecular and Cellular Physiology, Stanford University, Stanford, CA B370/P166 Investigating the mechanism of Sonic hedgehog signaling across a polarized epithelium. E. Kolenbrander1, T. Stearns2,3; 1Department of Developmental Biology, Stanford University, Stanford, CA, 2 Department of Biology, Stanford University, Stanford, CA, 3Department of Genetics, Stanford University, Stanford, CA B371/P167 Measuring Calcium Dynamics in the Primary Cilium of Mammalian Cells in Culture. W.C. Salmon1,2, P.G. Czarnecki2,3, J.V. Shah2,3; 1W.M. Keck Imaging Facility, Whitehead Institute, Cambridge, MA, 2Department of Systems Biology, Harvard Medical School, Boston, MA, 3Renal Division, Brigham and Women’s Hospital, Boston, MA

Cytokinesis 1 B373/P168 FLIRTing with cell division during development to study the spatiotemporal regulation of protein function in vivo. S. Sundaramoorthy1, T. Davies1, Y. Zhuravlev1, S. Hirsch1, M. Shirasu-Hiza2, J. Dumont3, J.C. Canman1; 1Pathology and Cell biology, Columbia University Medical Center, New York, NY, 2Genetics and Development, Columbia University Medical Center, New York, NY, 3Cell division and Reproduction, Institut Jacques Monod, Paris, France B374/P169 Aberrant cytokinesis signaling and mechanics in epothilone-treated

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Xenopus eggs. C.M. Field1,2, T.J. Mitchison1,2; 1Systems Biology, Harvard Medical School, Boston, MA, 2Marine Biological Laboratory, Woods Hole, MA B375/P170 Spindle pole localization of CK1 is necessary for mitotic checkpoint function. Z.C. Elmore1, K.L. Gould1; 1Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN B376/P171 Localization of LET-99 by a PAR-independent mechanism and its role in aster positioned cytokinesis. K.L. Price1, L.S. Rose1; 1Molecular and Cellular Biology, UC Davis, Davis, CA B377/P172 Sperm astral microtubules may be required to interact with the cell cortex for proper nuclear centering, capture of the female pronucleus, and proper localization of embryonic determinants. S.P. Ruvolo1, M. Johnathan1, A. McDougall2, D.R. Burgess1; 1Biology, Boston College, Chestnut Hill, MA, 2Laboratoire de Biologie du Développement de Villefranche-sur-mer, Sorbonne Universités, Villefranche sur-mer, France B378/P173 Cytokinesis requires the temporal and spatial regulation of PAR5 and ZEN-4 by the conserved RNA binding protein ATX-2. M.M. Gnazzo1, E.E. Uhlemann1, A. Villarreal1, E. Dominguez1, M. Shiayama2, A.R. Skop1; 1Genetics, University of Wisconsin, Madison, WI, 2 Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA B379/P174 The role of Kinesin-6 KIF20B in cytokinesis in a human cell line. K.M. Janisch1, S. Lim1, J.M. Dardick1, K.C. McNeely1, N.D. Dwyer1; 1Cell Biology, University of Virginia, Charlottesville, VA B380/P175 Multicellular context contributes to cell type specific protection against cytokinesis failure. T. Davies1, N. Romano Spica1, Y. Zhuravlev1,2, M. Shirasu-Hiza2, J. Dumont3, J.C. Canman1; 1Department of Pathology and Cell Biology, Columbia University, New York, NY, 2Department of Genetics and Development, Columbia University, New York, NY, 3Institut Jacques Monod, Paris, France B381/P176 The non-canonical Anillin ANI-2 stabilizes midbody components and maintains membrane integrity of the primordial germ cells during C. elegans embryogenesis. E. Goupil1, J. Labbé1; 1Institut de Recherche en Immunologie et en Cancérologie, Université de Montréal, Montréal, QC B382/P177 Loss of the Kinesin-6 Kif20b causes abnormalities in cytokinesis and apoptosis in neural progenitor cells. J.L. Neville1, K.C. McNeely1, N.D. Dwyer1; 1Cell Biology, University of Virginia, Charlottesville, VA

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SUNDAY

B358/P154 Localization of ciliary GPCRs to distinct populations of neurons in the olfactory bulb. J.C. McIntyre1; 1Neuroscience, Center for Smell and Taste, University of Florida, Gainesville, FL

Sunday Poster Session

Board No./Presentation No. B383/P178 The post-mitotic midbody is a novel regulator of cell proliferation. E.M. Peterman1, R. Prekeris1; 1Cell and Developmental Biology, University of Colorado - Anschutz Medical Campus, Aurora, CO B384/P179 A Potential Role for Midbodies in Developing Tissues of C. elegans. X. Bai1, B. Chen2, R. Simmons1, C. Turpin1, L. Uehlein1, D. Mitchell1, E. Betzig2, J.N. Bembenek1; 1BCMB, UT Knoxville, Knoxville, TN, 2Janelia Research Campus, Ashburn, VA B385/P180 Molecular mechanisms generating genetic instability in polyploid cells with extra centrosomes. M. Nano1, D. Gogendeau2, R. Basto1; 1UMR144, CNRS, Institut Curie, Paris, France, 2CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Univ. Paris Sud, Université Paris-Saclay, France B386/P181 CoA Synthase Regulates Aurora A and mitotic fidelity via CBPmediated TPX2 acetylation. C. Lin1, X. Tang1, J. Wu1, D. Qu1, M. Kitagawa2, W. Thompson3, T. Yao4, S. Lee2, J. Chi1; 1Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, 2Graduate Medical School, Duke-NUS, Singapore, Singapore, 3Proteomics and Metabolomics Core Facility, Duke University, Durham, NC, 4Department of Pharmacology and Cancer Biology, Duke University, Durham, NC B387/P182 Separase protease function is required for cytokinesis and membrane trafficking in addition to chromosome segregation. X. Bai1, J.N. Bembenek1; 1Biochemistry and Cellular and Molecular Biology, the University of Tennessee, Knoxville, TN B388/P183 Mitochondria dynamics and functions during cytokinesis in early Caenorhabditis elegans embryos. B. Hu1, Y. Li1, Y. Tse1; 1Department of Biology, Southern University of Science and Technology, Shenzhen, China B389/P184 Inhibition of autophagy enhances cytokinesis arrest-mediated apoptosis via promoting Bak activation and mitochondria-dependent caspase cascade activation in human Jurkat T cells. Y. Kim1,2, K. Kim1, M. Kim1, J. Park1, D. Jun1, J. Kim3, Y. Kim1; 1School of Life Science and Biotechnology, College of Natural Science, Kyungpook National University, Daegu, 41566, Korea, South, 2 Daegu Science High School, Daegu, 42110, Korea, South, 3Department of Biological Sciences, Andong National University, Andong, 36729, Korea, South B400/P185 Quantitative fitness analysis of cell-to-cell heterogeneity in aneuploid populations. A.R. Nelliat1, H. Tsai2, R. Li1,2; 1Department of Chemical and Bimolecular Engineering, Johns Hopkins University, Baltimore, MD, 2Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD

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Sunday Poster Session B401/P186 PRC1-labeled overlap microtubule bundles are associated with kinetochores in metaphase and contribute to their segregation in anaphase. B. Polak1, P. Risteski1, R. Buđa1, K. Vukušić1, A. Milas1, N. Pavin2, I.M. Tolic1; 1Division of Molecular Biology, Ruder Boskovic Institute, Zagreb, Croatia, 2 Department of Physics, Faculty of Science, University of Zagreb, Zagreb, Croatia B402/P187 TPXL-1 mediates aster-based clearing of contractile ring proteins from the cell poles during cytokinesis. E. Zanin1, K. Oegema2; 1Dep. II, Zell- und Entwicklungsbiologie D02.009B, Biocenter - LMU Munich, Planegg-Martinsried, Germany, 2UCSD, Dept. 0660, CMM-East 3080, Ludwig Institute for Cancer Research, La Jolla, CA B403/P188 Bga1 is a novel regulator for the localization of the β-glucan synthase Bgs1 in fission yeast. R. Davidson1, J. Pontasch1, J. Wu1; 1Molecular Genetics, The Ohio State University, Columbus, OH B404/P189 Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis. Y. Liu1, I. Lee1,2, M. Sun3, C.A. Lower1, J. Ma3, J. Wu1,4; 1Molecular Genetics, The Ohio State University, Columbus, OH, 2Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 3Surgery, Davis Heart and Lung Research Institute, Columbus, OH, 4Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH B405/P190 Silver nanoparticle exposure leads to binucleation through cytokinesis failure in retinal epithelial cells. E. Garcia1, C. Alms2, C. Kelly1, A. Smith1, L. Marr3, D. Cimini1; 1Biological Sciences and Biocomplexity Institute, Virginia Tech, Blacksburg, VA, 2University of Maryland, Baltimore County, Baltimore, MD, 3Environmental and Civil Engineering, Virginia Tech, Blacksburg, VA B406/P191 Roles of an Unc-13/Munc13 family protein Ync13 in fission yeast cytokinesis. Y. Zhu1, J. Hyun1, V. Purde1, J. Wu1; 1Molecular Genetics, The Ohio State University, Columbus, OH

Kinetochore Assembly and Functions 1 B407/P192 Monitoring Aurora B kinase activity in response to changes in kinetochore-microtubule attachment stability during mitosis. J.A. DeSimone1,2, D.A. Compton1,2; 1Norris Cotton Cancer Center, Lebanon, NH, 2Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH

B408/P193 Overexpression of Aurora B reduces its kinase activity. E.M. Britigan1, A.L. Lasek2, L. Wang3, A. Audhya3,4, M.E. Burkard2,4, A. Roopra4,5, B.A. Weaver1,4; 1Cell and Regenerative Biology, University of Wisconsin, Madison, WI, 2Medicine, University of Wisconsin, Madison, WI, 3 Biomolecular Chemistry, University of Wisconsin, Madison, WI, 4Carbone Cancer Center, University of Wisconsin, Madison, WI, 5Neuroscience, University of Wisconsin, Madison, WI B409/P194 Sli15/INCENP Spindle Association Promotes Chromosome Biorientation Independently of Clustering-Mediated Ipl1/Aurora B Kinase Activation. S. Fink1, K.L. Turnbull2, A.B. Desai2, C.S. Campbell1; 1Chromosome Biology, Max F Perutz Laboratories, University of Vienna, Vienna, Austria, 2 Cellular and Molecular Medicine, Ludwig Cancer Research, University of California San Diego, San Diego, CA B410/P195 TIP60-elicited acetylphosphorylation cross-talk ensures accurate chromosomal segregation. X. Liu1, F. Mo1, X. Zhuang1, X. Yao1; 1Anhui Key Laboratory of Cellular Dynamics and Chemical Biology, University of Science & Technology of China, Hefei, China B411/P196 The C-terminal domain of topoisomerase II alpha has a noncatalytic function in Aurora B recruitment to inner centromeres during mitosis. H. Edgerton1, M. Johansson1, D. Keifenheim1, S. Mukherjee1, J.M. Chacon1, J. Bachant2, M.K. Gardner1, D.J. Clarke1; 1Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, 2Cell Biology and Neuroscience, University of California, Riverside, Riverside, CA B412/P197 Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus. A.W. Grenfell1, M. Strzelecka1,2, R. Heald1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Qiagen, Hilden, Germany B413/P198 Polo and the response to DNA damage during mitosis. C. Landmann1,2, E. Montembault1,2, A. Royou1,2; 1Institut Européen de Chimie et Biologie, Bordeaux, France, 2Institut de Biochimie et Génétique Cellulaire, Bordeaux, France B414/P199 Myosin phosphatase targeting subunit 1 (MYPT1) mediates the antagonistic actions of Cyclin A/Cdk1 and Plk1 on k-MT attachment stability to promote efficient error correction in early mitosis. A.G. Dumitru1, S.F. Rusin1, A. Kettenbach1,2, D. Compton1,2; 1Biochemistry Cell Biology, Dartmouth Geisel School of Medicine, Hanover, NH, 2Norris Cotton Cancer Center, Dartmouth Geisel School of Medicine, Lebanon, NH

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Board No./Presentation No. B415/P200 Synthetic lethal genetic interactions in spindle assembly checkpoint (SAC)-deficient human cells. J.A. Raaijmakers1, R. Van Heesbeen1, V. Blomen2, L. Janssen1, F.V. Diemen2, T. Brummelkamp2, R.H. Medema1; 1Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, Netherlands, 2Division of Biochemistry, The Netherlands Cancer Institute, Amsterdam, Netherlands

B417/P202 Ensuring transmission of the centromere through meiosis and early development. S.Z. Swartz1, I.M. Cheeseman1; 1Whitehead Institute for Biomedical Research, Cambridge, MA B418/P203 Centromere maintenance through error correction of CENP-A deposition during DNA replication. Y. Nechemia-Arbely1, K.H. Miga2, M. McMahon1, O. Shoshani1, D. Fachinetti1, A. Lee1, B. Ren1, D.W. Cleveland1; 1Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, UCSD, LA JOLLA, CA, 2Center for Biomolecular Science Engineering, UCSC, Santa Cruz, CA B419/P204 The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule dynamics and kinetochore structure. F. Renda1,2, C. Pellacani2,3, A. Strunov4,5, E. Bucciarelli3, V. Naim2,6, G. Bosso2, E. Kiseleva4,5, S. Bonaccorsi2, D.J. Sharp7, A. Khodjakov1, M. Gatti2,3,4, M.P. Somma3; 1Wadsmorth Center, New York State Department of Health, Albany, NY, 2 Department of Biology and Biotechnology “Charles Darwin”, Sapienza, University of Rome, Rome, Italy, 3Institute of Molecular Biology and Pathology - IBPM CNR, Rome, Italy, 4Institute of Molecular and Cellular Biology, Siberian Branch of RAS, Novosibirsk, Russia, 5Institute of Cytology and Genetics, Siberian Branch of RAS, Novosibirsk, Russia, 6Université ParisSaclay, UMR 8200 CNRS, Gustave Roussy, Villejuif Cedex, France, 7Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY

Centrosome Assembly and Functions 1 B420/P205 Interaction and phosphorylation of SAS-5 by ZYG-1 may be important in centriole assembly. P. Sankaralingam1, K. OConnell1; 1National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

B421/P206 Plk4 phosphorylates Ana2 to block association and inhibit centriole duplication. T.A. McLamarrah1, D.W. Buster1, C. Boese1, N. Hollingsworth1, G.J. Brian2, N.M. Rusan2, C. Brownlee1, G.C. Rogers1; 1Cancer Biology, University of Arizona, Tucson, AZ, 2National Heart, Lung and Blood Institute, NIH, Bethesda, MD B422/P207 The Cullin4-DDB1 E3 Ubiquitin Ligase Complex regulates Plk4- dependent centriole duplication. I.M. Hoffmann1, A. Kratz1, S. Freiss1; 1Cell Cycle Control and Carcinogenesis, German Cancer Research Center, Heidelberg, Germany B423/P208 WBP11 is a novel regulator of centriole biogenesis. E.M. Park1, P. Scott1, K. Clutario1, J. Smith1, A.J. Holland1; 1Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD B424/P209 Human microcephaly protein RTTN interacts with STIL and is required for assembly of full-length centrioles. H. Chen1,2, C. Wu2,3, Y. Lin2, W. Wang3, T.K. Tang2; 1Graduate Institution of Life Sciences, National Defense Medical Center, Taipei, Taiwan, 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, 3National Yang-Ming University, Taipei, Taiwan B425/P210 Coordination between centrosomal linker dissolution and microtubule pathway drives centrosome separation at the onset of mitosis. A. Pastor Peidro1, M. Panic1, S. Hata1, E. Schiebel1; 1ZMBH, University of Heidelberg, Heidelberg, Germany B426/P211 Cleavage of the SUN-domain protein Mps3 promotes centrosome separation in budding yeast meiosis. H. Yu1, B.A. Koch1, H. Jin1; 1Biological Science, Florida State University, Tallahassee, FL B427/P212 Characterizing the interaction between CK1δ/ε and GAPVD1. R.X. Guillen1, J. Chen1, K.L. Gould1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN B428/P213 Spatial control of centrosomes is required for germline development. C.W. Shebelut1, N.M. Rusan2, E.R. Gavis3, G. Deshpande3, P. Schedl3,4, D.A. Lerit2,5; 1University of Virginia School of Medicine, Charlottesville, VA, 2Cell Biology and Physiology Center, NHLBI, Bethesda, MD, 3Department of Molecular Biology, Princeton University, Princeton, NJ, 4Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia, 5Department of Cell Biology, Emory University School of Medicine, Atlanta, GA B429/P214 Using laser ablation to examine centriole function in mitotic centrosome assembly. T. Laos1, G. Cabral1, A. Dammermann1; 1Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B430/P215 Centrosome amplification in cancer occurs primarily by de novo overduplication and requires additional adaptations to overcome disrupted cell physiology. R.A. Denu1, M.E. Burkard1; 1Medicine, University of Wisconsin-Madison, Madison, WI B431/P216 The molybdenum cofactor biosynthesis and tRNA thiolation are linked to the centrosome. Y. Neukranz1, S. Leimkuehler1, R. Graef1; 1Biochemistry and Biology, University of Potsdam, Potsdam, Germany B432/P217 INPP5E preserves genomic stability through regulation of mitosis. E.A. Sierra Potchanant1, D.M. Cerabona1,2, Z. Abdul-Sater1, Y. He1, Z. Sun1, J.R. Gehlhausen1,2, G. Nalepa1,2,3,4; 1Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 2 Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 3Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 4Division of Pediatric HematologyOncology, Bone Marrow Failure Program, Riley Hospital for Children, Indianapolis, IN

Chromosome Organization B433/P218 Dissecting the role of microtubule detyrosination in kinetochore microtubule stability and error correction during mitosis. L. Ferreira1, M. Barisíc2, B. Orr1, H. Maiato1; 1Institute for Innovation and Health Research of University of Porto, Porto, Portugal, 2Cell Division Laboratory, Danish Cancer Society Research Centre, Copenhagen, Denmark B434/P219 Chromosome movement to one pole in the absence of kinetochore microtubules in Mesostoma ehrenbergii spermatocytes. E. Fegaras1, A. . Forer1; 1Biology, York University, Toronto, ON B435/P220 Cleavage furrow ingression is not required for segregation of the amphitelically attached univalent X chromosome in the spittlebug P. spumarius. K.D. Felt1, M.B. Lagerman1, N.A. Ravida1, L.V. Paliulis1; 1Biology Department, Bucknell University, Lewisburg, PA B436/P221 Asymmetric microtubule activity facilitates differential epigenetic inheritance in Drosophila male germline stem cell. R. Ranjan 1, X. Chen1; 1Department of Biology, Johns Hopkins University, Baltimore, MD

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SUNDAY

B416/P201 A new toolbox for the fly Sciara - a new/old model system that disobeys the rules for chromosome movement on spindles. S.A. Gerbi1, Y. Yamamoto1, J. Urban1, J. Bateman2; 1BioMed Division; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, 2Department of Biology, Bowdoin College, Brunswick, ME

Sunday Poster Session

Board No./Presentation No. B437/P222 H3.3 Serine 31 phosphorylation at pericentromeric heterochromatin regulates chromosome segregation. C.A. Day1, A.K. Langfald1, S.R. Fadness1, K.T. Vaughan2, E.H. Hinchcliffe1; 1Hormel Institute, University of Minnesota, Austin, MN, 2Department of Biological Sciences, Universtiy of Notre Dame, Notre Dame, IN B438/P223 Mechanisms to maintain centromere stability in human cells. S. Giunta1, H. Funabiki1; 1The Rockefeller University, New York, NY B439/P224 Successful inclusion of latesegregating chromosomes through channels in the nuclear envelope is dependent upon Aurora B-mediated HP1-chromatin dynamics. B. Warecki1, W. Sullivan1; 1MCD Biology, University of California, Santa Cruz, Santa Cruz, CA B440/P225 DNA damage and mislocalization of Aurora B contribute to chromatin bridge formation. M. Jo1,2,3, J. Ahn1,2,3, J. Lee1,2,3; 1Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Korea, 2Genomic Instability Research Center, Ajou University School of Medicine, Suwon, Korea, 3 Department of Biomedical Sciences, Graduate School of Ajou University, Suwon, Korea, South B441/P226 BAF forms a rigid shell around anaphase chromosomes to prevent micronucleation. M. Samwer1, P.S. Schmalhorst2, M. Schneider1, R. Höfler1, D.W. Gerlich1; 1Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna, Austria, 2Institute of Science and Technology Austria (IST Austria), Vienna, Austria B443/P228 Perturbing spindle formation dynamics by Plk4 overexpression can trigger fragile chromosome breakage. M. Manil-Segalen1, M. Łuksza1, J. Kanaan1, V. Marthiens2, S.I. Lane3, K.T. Jones3, R. Basto2, M. Verlhac1; 1Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS, INSERM, PSL Research University, Paris, France, 2Centre de Recherche, Institut Curie, Paris, France, 3 Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, United Kingdom B444/P229 What drives chromosomal instability in high-grade serous ovarian cancer? N. Tamura1, N. Shaikh1, J.R. McGuinness1, D. Bowtell2, F. Balkwill3, E. Petermann4, S.E. McClelland1; 1Department of Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom, 2Peter MacCallum Cancer Centre, Melbourne, Australia, 3 Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom, 4 Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom

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Sunday Poster Session B445/P230 Microtubule dynamics and chromosome-associated cohesin counterbalance to determine the rates of cohesion fatigue. H. Sapkota1,2, E. Wasiak1, J. Daum 1, G. Gorbsky1,2; 1Cell Cycle and Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2 Dept. of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK B446/P231 Investigating the role of DNA condensation in chromosome segregation. K.R. Salmon1, D.A. Compton1; 1Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH B447/P232 Investigating the role of Condensins in mitotic chromosome architecture using quantitative superresolution microscopy. N. Walther1, B. Koch1, M. Kueblbeck1, Y. Cai1, M.J. Hossain1, A.Z. Politi1, M. Lampe2, J. Ries1, J. Ellenberg1; 1Cell Biology Biophysics Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, 2Advanced Light Microscopy Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany B448/P233 Condensin loading onto DNA reconstituted in vitro. I.A. Shaltiel1, S. Bisht1, Y. Frosi1,2, C.H. Haering1; 1Cell Biology Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany, 2 p53 Laboratory, A*Star Biomedical Sciences Institute, Singapore, Singapore B449/P234 Resolution of mitotic defects induced by carcinogen treatment in cancer and noncancer cells. R.G. Hartling1, N.J. Quintyne1; 1Department of Biology, State University of New York at Fredonia, Fredonia, NY B450/P235 3D-CLEM reveals that a major portion of mitotic chromosomes is not chromatin. D.G. Booth1,2, A. Beckett3, O. Molina1, I. Samejima1, V. Larionov4, N. Kouprina4, I. Prior3, W.C. Earnshaw1; 1Wellcome Trust Center for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom, 2Center for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom, 3Translational Medicine, University of Liverpool, Liverpool, United Kingdom, 4National Cancer Institute, National Institutes of Health, Bethesda, MD B451/P236 Contributions of Esco1 and Esco2 to cohesion establishment. E. Lima Da Silva1, R. Alomer1,2, K. Piekarz1,2, J. Chen1, S. Rankin1,2; 1Cell Cycle and Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK B452/P237 Dynamics of the DNA Damage Response module during mitosis. P. Pierre-elies1,2, A. Royou1,2; 1Institut de Biochimie et Génétique Cellulaires, Bordeaux, France, 2Institut Européen de Chimie et Biologie, Pessac, France

B453/P238 From transient endoreplication to mitosis: a new route to CIN in p53 positive cells. S. Chen1,2, S.E. Yde2, J.Y. Zhang2, B.R. Calvi2, C.E. Walczak1,2; 1Medical Science, Indiana University Bloomington, Bloomington, IN, 2 Biology Department, Indiana University Bloomington, Bloomington, IN B454/P239 Structure-Function Analysis of Esco1 and Effects on Cohesion Dynamics. D.E. Bender1,2, E.M. Lima Da Silva2, J. Chen2, S. Rankin1,2; 1Cell Biology, Oklahoma University Health Science Center, Oklahoma City, OK, 2Cell Cycle and Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK

Spindle Assembly 1 B455/P240 Kinetochore Microtubules indirectly link Chromosomes and Centrosomes in C. elegans Mitosis. S. Redemann1, J. Baumgart2, N. Lindow3, S. Fürthauer4, E. Nazockdast4, A. Kratz3, S. Prohaska3, J. Brugués2,5, M.J. Shelley4, T. Müller-Reichert1; 1Experimental Centre Medical Faculty, TU Dresden, Dresden, Germany, 2Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, 3Zuse Institute, Berlin, Germany, 4 The Courant Institute of Mathematical Science, New York, United States, 5Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B456/P241 Seeking stable equilibrium? The evolution of centrosome and chromosome number in newly formed tetraploid cells. N.C. Baudoin1, I. Quintanilla2, M. Giam Xue Lin3, D. Cimini1, G.I. Rancati3, J. Nicholson1, K. Soto1, J. Camps2; 1Department of Biological Sciences and Biocomplexity Institute, Virginia Tech, Blacksburg, VA, 2Gastrointestinal and Pancreatic Oncology Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Barcelona, Spain, 3Institute of Medical Biology, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore B457/P242 Monotelic end-on kinetochore attachment is sufficient to impose interkinetochore tension. s. cabello1, c. reyes1, s. tournier1, Y. Gachet1; 1LBCMCP, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, TOULOUSE, France B458/P243 Feedback and spatial organization of the Ran pathway by spindle microtubules. D. Oh1,2,3, C. Yu3, D.J. Needleman1,2,3; 1John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 2FAS Center for Systems Biology, Harvard University, Cambridge, MA, 3 Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Sunday Poster Session B466/P251 Kip2p is required for maintenance of normal spindle dynamics and cell cycle progression. B. Augustine1, C.F. Chin1, F.M. Yeong1; 1Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

B460/P245 Collective organization of microtubules by minus end directed motor proteins. P.J. Foster1,2, S. Fürthauer3,4, B. Laderman2,5, S.C. EmsMcClung6, C.E. Walczak6, M.J. Shelley4,7, D.J. Needleman1,2,3; 1John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 2FAS Center for Systems Biology, Harvard University, Cambridge, MA, 3 Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 4Courant Institute of Mathematical Science, New York University, New York, NY, 5 Department of Physics, Harvard University, Cambridge, MA, 6Medical Sciences, Indiana University, Bloomington, IN, 7Center for Computational Biology, Simons Foundation, New York, NY

B467/P252 Tiny Yeast Comet 1 (Tyc1) inhibits both Cdc20 and Cdh1-dependent APC/C activity in vitro and interacts directly with APC/C. H. Chen1, Y. Chu1, T. Chen1, Y. Wu1, W. Tsai1, Y. Ding1, A. Huang1, L. Wang1, S.C. Schuyler1,2; 1Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, 2Department of Colorectal Surgery, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan

B461/P246 The Role of ActinMicrotubule Crosslinker Shortstop in Cell Division. E.B. Dewey1, A. Parra1, C.A. Johnston1; 1Department of Biology, University of New Mexico, Albuquerque, NM B462/P247 Germline precursor cells exhibit enhanced spindle assembly checkpoint activity that is dependent on PAR polarity regulators. A.R. Gerhold1, P.S. Maddox2, J. Labbé1; 1Université de Montréal, Institute for Research in Immunology and Cancer, Montréal, QC, 2 Department of Biology, University of North Carolina, Chapel Hill, Chapel Hill, NC B463/P248 Investigating mitotic spindle size regulation by importin α. C.W. Brownlee1, M.D. Vahey1, D.A. Fletcher1, R. Heald1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States B464/P249 Meiotic drive depends on spindle asymmetry induced by cortical proximity. T. Akera1, L. Chmatal1, K. Yang1, C. Janke2, R.M. Schultz1, M.A. Lampson1; 1Biology, University of Pennsylvania, Philadelphia, PA, 2Signaling, Neurobiology and Cancer, Institut Curie, Orsay, France B465/P250 ATP depletion during mitotic arrest induces mitotic slippage, through APC/CCdh1 dependent cyclinB1 degradation. J. Ahn1,2,3, J. Lee1,2,3; 1Biochemistry and Molecular Biology, Ajou University, Suwon, Korea, South, 2Biomedical Sciences, Ajou University, Suwon, Korea, South, 3Genomic instability Research Center, Ajou University, Suwon, Korea, South

B468/P253 Peptides derived from the Mitotic Arrest-Deficient 2 (Mad2)-binding motif of Cell Division Cycle 20 (Cdc20) disrupt Anaphase-Promoting Complex (APC) enzyme activity. S.C. Schuyler1,2, Y. Ding1, Y. Chu1, H. Chen1, T. Chen1, Y. Wu1, W. Tsai1, Y. Liao1; 1Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, 2Department of Colorectal Surgery, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan B469/P254 NDP52 integrates astral microtubule plus-end dynamics to cortical actin filament length control to ensure an accurate spindle orientation. H. Yu1,2,3, B. Qin1,2, X. Yao1,2,3; 1Anhui Key Laboratory of Cellular Dynamics Chemical Biology, Hefei, China, 2Laboratory for Organelle Dynamics Plasticity Control, University of Science Technology of China School of Life Sciences, Hefei, China, 3Hefei National Laboratory for Physical Sciences at Nanoscale, Hefei, China B470/P255 C. elegans male meiotic spindles are distinct from other centrosomal spindles. G. Fabig1, J. Brugués2, D.S. Chu3, T. MüllerReichert1; 1Medical Faculty “Carl Gustav Carus”, TU Dresden, Dresden, Germany, 2 MPI-CBG, Dresden, Germany, 3Department of Biology, SFSU, San Francisco, CA B471/P256 Tiny Yeast Comet 1 (TYC1) encodes a budding yeast protein identified by homology to human p31Comet that induces a microtubule poison sensitivity phenotype when overexpressed. C. Lin1, A. Huang1, L. Wang1, S.C. Schuyler1,2; 1Department of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan City, Taiwan, 2Department of Colorectal Surgery, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Cancer Therapy 1 B473/P257 The role of emerin in coupling Wnt/β-catenin signalling to genomic instability in cancer. P. Ghanbari1, M. Wheeler1, A. Stubenvoll1, T. Braun1, R. Savai2; 1Dept. Development and Remodelling of the Heart, Max-PlanckInstitute for Heart and Lung Research, Bad Nauheim, Germany, 2Dept. Molecular Mechanisms in Lung Cancer, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany B474/P258 Effect of hyperlipidemia and application of lovastatin on lung carcinogenesis: an in vitro and in vivo study. J. Wang1, C. Wu1; 1Pharmacy, Taipei Medical University, Taipei, BC B475/P259 Phosphatidylserine mediated phagocytosis of HeLa by Retinal Pigment Epithelium. K. Suggs1, C. Corbo1, J. Blaize1; 1Biological Sciences, Wagner College, Staten Island, NY B476/P260 Targeting of claudin proteins for tumor cell killing. A. Becker1, S.C. Hammer2,3, M. Leskau1, B.L. Schlingmann4, A. Ngezahayo1; 1Institute of Biophysics, Leibniz University Hannover, Hannover, Germany, 2Small Animal Clinic, University of Veterinary Medicine Hannover, Hannover, Germany, 3Division of Medicine, Hematology Oncology and Palliative Medicine, University of Rostock, Rostock, Germany, 4Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA B477/P261 Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth through cellular senescence induction. K. Matsumura1, S. Nakata1, K. Taniguchi1, H. Ii1, E. Ashihara2, S. Kageyama3, A. Kawauchi3, T. Yoshiki1,3; 1Clinical oncology, Kyoto Pharmaceutical University, Kyoto, Japan, 2 Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan, 3Urology, Shiga University of Medical Science, Shiga, Japan B478/P262 Interleukin-24 promotes tumor cell-specific apoptosis through cAMPdependent protein kinase (PKA) pathway. L.E. Persaud1,2, M. Sauane1,2; 1Biology, Herbert H. Lehman College, City University of New York, Bronx, NY, 2Biology, The Graduate Center, City University of New York, Bronx, NY B479/P263 Inducing tumor cell apoptosis by a small molecule activating Bax. A.M. Neely1; 1Pharmacology and Toxicology, University of Louisville, Louisville, KY B480/P264 A novel peptide that activates the EphA2 receptor and decreases cell migration. D.S. Alves1, J.L. MorrellFalvey2, F.N. Barrera1; 1BCMB, University of Tennessee, Knoxville, TN, 2Biological and Nanoscale Systems BioSciences Division, Oak Ridge National Laboratory, Oak Ridge, TN

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SUNDAY

B459/P244 A decreasing gradient in metaphase centromere tension leads to a graded, multi-level cellular response in mitosis. S. Mukherjee1, D.G. Tank1, Q. Yang1, M.K. Gardner1; 1Genetics, Cell Biology, and Development, University of Minnesota, Twin Cities, MN

Board No./Presentation No. B481/P265 Quercetin induces apoptosis in leukemia models, in part by suppressing class I histone deacetylases. M.C. Alvarez De Prax1, V. Maso1, C.O. Torello1, S.T. Saad1; 1Hemocentro, Unicamp, Campinas, Brazil B482/P266 Histone Deacetylase (HDAC) Inhibition Induces IkB Kinase (IKK)dependent IL-8 Expression in Ovarian Cancer Cells. H.R. Gatla1, Y. Zou1, M.M. Uddin1, B. Singha1, A. Vancura1, I. Vancurova1; 1Biology, St. John’s university, New York City, NY B483/P267 Bcl3 has a pro-survival and pro-inflammatory function in ovarian cancer cells. Y. Zou1, P. Bu1, H.R. Gatla1, M.M. Uddin1, I. Vancurova1; 1Biology, St. John’s University, New York City, NY B484/P268 Cathepsin S expression is upregulated by 5-HT7 receptor-dependent serotonin signaling in triple negative human breast cancer cells. J. Gautam1, J. Kim1; 1College of Pharmacy, Yeungnam University, Gyeongsan, Korea, South B485/P269 Rosehip extracts (Rosa canina) prevent African American triple negative breast cancer cell migration and invasion by blocking MMP-1/2/9 expression and activity. P.D. Cagle1, P.M. Martin2; 1EES/ Biology, NC Agricultural and Technical State University, Greensboro, NC, 2Biology, NC Agricultural and Technical State University, Greensboro, NC B486/P270 AU-1 from Agavaceae plants causes transient increase in p21/Cip1 expression in renal adenocarcinoma ACHN cells in a miR-34-dependent manner. T. Fujino1, A. Yokosuka1, Y. Mimaki1, M. Hayakawa1; 1School of pharmacy, Tokyo university of pharmacy and life sciences, Hachioji, Japan B487/P271 Paclitaxel treatment of MDAMB-231 breast cancer cells stabilizes cytoplasmic p27Kip1 and reduces total intracellular stathmin. S. Lobert1, M.E. Graichen1; 1School of Nursing, University of Mississippi Medical Center, Jackson, MS

Sunday Poster Session B501/P275 Targeting endoplasmic reticulum-resident proteins for the treatment of B cell cancer. C.A. Tang1, J. Del Valle2, C.A. Hu1; 1The Wistar Institute, Philadelphia, PA, 2Department of Chemistry, The University of South Florida, Tampa, FL B502/P276 Effects of Ganoderma lucidum extract (GLE) in triple-negative metastatic breast cancer migration and protein expression. G. OrtizSoto1, A. Acevedo-Díaz2, T.J. Rios1, Y. Loperena1, L.A. Cubano3, M.M. MartinezMontemayor1; 1Department of Biochemistry, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 2University Gardens High School, San Juan, PR, 3 Department of Anatomy and Cell Biology, Universidad Central del Caribe-School of Medicine, Bayamon, PR B503/P277 Microdose-induced drug-DNA adducts as biomarkers of chemotherapy resistance in bladder cancer. M. Zimmermann1,2, S. Wang1, T. Lin1, H. Zhang1, M. Malfatti3, G. Cimino2, J. Keck4, R. deVere White5, K. Turteltaub3, C. Pan1,2,6, P.T. Henderson1,2; 1Department of Internal Medicine, Division of Hematology and Oncology, University of California Davis, Sacramento, CA, 2Accelerated Medical Diagnostics Incorporated, Berkeley, CA, 3 Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA, 4The Jackson Laboratory, Bar Harbor, ME, 5Department of Urology, University of California Davis, Sacramento, CA, 6VA Northern California Healthcare System, Mather, CA B504/P278 Small-molecule destabilizing both β-catenin and Ras via binding of the Axin-RGS domain suppresses colorectal cancer. W. Ryu1,2, P. Cha1,2, Y. Cho1,2, S. Lee1,2, W. Jeong1,2, K. Choi1,2; 1Translational Research Center for Protein Function Control, Yonsei university, Seoul, Korea, South, 2Biotechnology, Yonsei university, Seoul, Korea, South

B488/P272 Prolonged mitotic arrest induced by Wee1 inhibition sensitized breast cancer cells to paclitaxel. C.W. Lewis1, Z. Jin1, D. Macdonald1, G.K. Chan1; 1Oncology, University of Alberta, Edmonton, AB

B505/P279 Screening of Novel SHetA2 Analogs on Human Breast and Prostate Cancer Cells. S.M. Francis1, H. Zou2, S. Liu1, M.C. Louie1,2, V. Rajagopalan1; 1College of Pharmacy, Touro University California, Vallejo, CA, 2Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, CA

B489/P273 Proteasome inhibition induces IL_8 expression in triple negative breast cancer cells. M.M. Uddin1, H.R. Gatla1, Y. Zou1, I. Vancurova1; 1Department of Biological Sciences, St. John’s University, New York, NY

B506/P280 Modified Panax ginseng extract regulates autophagy by AMPK signaling in A549 human lung cancer cells. J. Eunbi1, S. Kang1, I. Jang1; 1Biocnovergence, Korea Basic Science Institute, Daejeon, Korea, South

B500/P274 BJ-1113, an aminopyridinol derivative, induces pancreatic cancer cell apoptosis through PI3K inhibition. Y. Wang1, Y. Lee1, J. Gautam1, M. Park1, B. Jeong1, J. Kim1; 1College of Pharmacy, Yeungnam University, Gyeongsan, Korea, South

B507/P281 3,4,5’-Trismethoxybenzophenone exhibits antiviral and anticancer properties in vitro. C.J. Patton1, H. Kotturi1; 1Biology, University of Central Oklahoma, Edmond, OK

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B508/P282 Analysing the Cytotoxic Effects of Oleuropein on A549 Human Lung Adenocarcinoma Cells. E. COMLEKCI1, H.M. Kutlu1, D. Vejselova1; 1Biology, Anadolu University, Eskisehir, Turkey B509/P283 RAI14 regulates proliferation/ survival and migration of mutant KRas pancreatic cancer cells on fibronectin substrates. J. Hong1, Y. Adamian1, K. Bhakta1, M. Hoover1, J.A. Kelber1; 1Biology, California State University Northridge, Northridge, CA B510/P284 DNA damage response in neural cells following exposure to low and high LET radiation. H. Wang1, P. Saganti1; 1Texas AM Chancellor’s Research Initiative, Radiation Institute for Science and Engineering, Prairie View AM University, Prairie View, TX B511/P285 H10 peptide, a promising therapeutic and diagnosis tool to target Anterior Gradient protein 2 (AGR2) in cancer. C. Garri1, S. Howell2, A. Ghaffarizadeh1, E. Juarez1, P. Macklin1, D. Agus1, K. Kani1, R. Roberts2; 1Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA, 2Department of Chemical Engineering, University of Southern California, Los Angeles, CA

Oncogenes and Tumor Suppressors 1 B512/P286 The Y-located TSPY and its X-homologue are co-activator and corepressor respectively for androgen receptor functions in human cancers and diseases. Y.C. Lau1,2, Y. Li1,2, T. Kido1,2; 1Medicine, University of California, San Francisco, San Francisco, CA, 2VA Medical Center, San Francisco, CA B513/P287 Examining of Morphological Changes on B13 Treated Human Lung Adenocarcinoma Cells. H.M. Kutlu1, D. Vejselova1; 1Biology, Anadolu University, Eskisehir, Turkey B514/P288 Identification of RAN binding protein 6 as EGFR feedback regulator and candidate tumor suppressor. W. Hsieh1,2, B. Oldrini2,3, H. ErdjumentBromage4, P. Codega2, I. Vivanco5, D. Rohle2, C. Campos2, C.M. Bielski6, B.S. Taylor2,6,7, P. Tempst4, M. Squatrito3, I.K. Mellinghoff1,2,8; 1Pharmacology, Weill Cornell Graduate School of Medical Sciences, New York, NY, 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 3 Seve Ballesteros Foundation Brain Tumor Group, Spanish National Cancer Research Centre, Madrid, Spain, 4Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 5Molecular Addiction Team, Division of Cancer Therapeutics, The Institute of Cancer Research, London, United Kingdom, 6Epidemiology and

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, 7Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, 8Neurology, Memorial Sloan Kettering Cancer Center, New York, NY B515/P289 Role of c-myc in the regulation of MAP kinase signaling and apoptosis. C.T. Wales1, R.A. Gristock1, M.J. Jones1, A.T. Jacobs1; 1Pharmaceutical Sciences, University of Hawaii at Hilo, Hilo, HI

B517/P291 Characterization of the expression and function of LOX-1 (OLR1) in human glioblastomas. F.S. Rodriguez Vásquez1, F. Espinoza1, E. Peña1, F. Gutierrez1, N. Gutiérrez1, M. González1, J.R. Toledo1; 1Pathophysiology, Universidad de Concepción, Concepción, Chile B518/P292 Aryl Hydrocarbon Receptor: an essential cog in Myc-driven cancers. S. Ramanathan1, N. BorensteinAuerbach1, Y. Hao1, M. Lafita Navarro1, N. Venkateswaran1, M. Conacci-Sorrell1; 1Cell Biology Department, UT Southwestern Medical Center, Dallas, TX B519/P293 Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival. M. Zimmermann1,2, A. Arachchige Don2, M. Donaldson1, T. Patriarchi1, M.C. Horne1,2; 1Pharmacology, University of California Davis, Davis, CA, 2Pharmacology, University of Iowa, Iowa City, IA B520/P294 Mitochondrial Sirt3 supports cell proliferation by regulating glutaminedependent oxidation in renal cell carcinoma. E. Koh1, J. Choi1, Y. Lee1, K. Kim1; 1Department of Biochemistry and Molecular Biology, Institute of Genetic Science, Integrated Genomic Research Center for Metabolic Regulation, Yonsei University College of Medicine, Seoul, Korea, South B521/P295 VER155008 enhances lung cancer cells to TRAIL-induced cell death by CHOP-mediated DR5 and Redd1 upregulation. H. Jin1, S. Hong2,3, I. Park3, J. Lee1; 1KIRAMS Radiation Biobank, Korea Institute of Radiological and Medical Sciences, Seoul, Korea, South, 2Department of Translational Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea, South, 3Division of Basic Radiation Bioscience, Korea Institute of Radiological and Medical Sciences, Seoul, Korea, South

B522/P296 Modeling synovial sarcoma metastasis in the mouse: PI3’-lipid signaling and inflammation. J.J. Barrott1, A.J. Lazar2, K.B. Jones1; 1Orthopaedics and Oncological Science, Huntsman Cancer Institute, Salt Lake City, UT, 2Pathology and Translational Molecular Pathology, MD Anderson, Houston, TX B523/P297 Impact of the corticosteroid, clobetasol, on Subclones of Vulvar carcinoma cell line, UMSCV-6. M. Li1, C.L. Okorie1, J.E. Lewis1; 1Biology, State University of New York at Geneseo, Geneseo, NY B524/P298 Clobetasol treatment of vulvar carcinoma cell lines, UMSCV-2 and UMSCV-4 show evidence of entering into quiescence as reflected by decreased cellular metabolism. V. Mehta1, M.B. Stevens1, J.E. Lewis1; 1Biology, State University of New York at Geneseo, Geneseo, NY B525/P299 Ha-Ras-induced cell softening and transformation requires caveolin-1 down-regulation and augmented secretion of Wnt5a-containing exosome. M. Tang1, H. Lin1, H. Lin1; 1Physiology, National Cheng Kung University, Tainan, Taiwan B526/P300 Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer. H. Kwon1; 1SIMS, Soonchunhyang University, Choeonan, Korea, South B527/P301 Identification of Novel Parafibromin Protein Partners Using A Proteomic Approach. P.R. Adikaram1, J. Zhang1, M. Pandey1, W.F. Simonds1; 1NIDDK, National Institutes of Health, Bethesda, MD B528/P302 A Drosophila model of HPV E6-induced malignancy reveals essential roles for Magi and the insulin receptor. M. Padash Barmchi1, M. Gilbert2, M. Thomas3, L. Banks3, B. Zhang1, V.J. Auld2; 1Biological Sciences, University of Missouri, Columbia, MO, 2Department of Zoology, University of British Columbia, Vancouver, BC, 3Virology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy B529/P303 A novel role for Plk4: heterozygosity in mice acts as a genetic predisposition to hematological malignancy. B.C. LaBute1, D. Owen1, J.W. Hudson1; 1Biological Sciences, University of Windsor, Windsor, ON B530/P304 Differential Activation of P53 Downstream Genes in Malignant Melanoma Cells with Different Genetic Context. H. Sun1, C. Yu1, Y. Yang1; 1Biological Sciences, Emporia State University, Emporia, KS

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Invasion and Metastasis B531/P305 Can we use cell shape as biomarker of cancer cell invasiveness? E. Alizadeh1, S.M. Lyons2, K.A. Schuamberg2, J. Mannheimer2, J. Castle3, Z.R. Bodmer1,2, A. Prasad1,2; 1Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, 2School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 3Department of Biology, Colorado State University, Fort Collins, CO B532/P306 Studying shape changes of cancer cell lines with different degrees of invasiveness on hydrophobic and hydrophilic substrates using multivariate methods. J.I. Foss1,2, E. Alizadeh3, J. Castle4, A. Prasad1,3; 1Biomedical Engineering Department, Colorado State University, Fort Collins, CO, 2Mechanical Engineering Department, Colorado State University, Fort Collins, CO, 3Chemical and Biological Engineering Department, Colorado State University, Fort Collins, CO, 4 Department of Biology, Colorado State University, Fort Collins, CO B533/P307 Identification of A Polarized Ex(o)citing Machinery for Cancer Invasion: Lessons from Yeast to Man. C.C. Rohena1,2,3, N.N. Sun1,2, N. Aznar1,2, P. Ghosh1,2; 1Cell and Molecular Medicine, University of California San Diego, La Jolla, CA, 2Medicine, University of California San Diego, La Jolla, CA, 3Moores Cancer Center, University of California San Diego, La Jolla, CA B534/P308 V-ATPase-mediated Activation of Cellular and Secreted Cathepsins: Exploring Their Role in Breast Cancer Metastasis. A.M. Hinton1; 1Biology, Denison University, Granville, OH B535/P309 A novel MT1-MMP cytoplasmic binding protein that interferes with invadopodia formation and function to attenuate matrix remodeling and tumor cell invasion. L. Qiang1, H. Cao2,3, J. Chen2,3, G. Razidlo2,3, M.A. McNiven2,3; 1Biochemistry and Molecular Biology Program, Mayo Graduate School, Rochester, MN, 2Center for Digestive Diseases, Mayo Clinic, Rochester, MN, 3 Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN B536/P310 Characterizing the roles of Rab40b in invadopodia dynamics. E.S. Linklater1, A. Jacob1, R. Prekeris1; 1Cell and Developmental Biology, University of Colorado - Anschutz Medical Campus, Aurora, CO B537/P311 Cellular polarization and motility during invasion is driven by a combination of LKB1 farnesylation and kinase activity. S. Wilkinson1,2, A.I. Marcus2; 1Cancer Biology, Emory University, Atlanta, GA, 2Hematology/Medical Oncology, Emory University, Atlanta, GA

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SUNDAY

B516/P290 Investigating Novel Roles for FOXO factors in pten-null Cancer Cells. E. Martinez1, V. Fanniel1, L. Sanchez1, N. Vazquez1, R. Marks1, A. Salinas1, L. Sanchez1, J. Hirschmann1, A. Lopez1, W. Innis1, M.E. Keniry1; 1Biology, University of Texas Rio Grande Valley, Edinburg, TX

Sunday Poster Session

Board No./Presentation No. B538/P312 Defining the invasive biology of clinically relevant LKB1 mutations in lung cancer. R. Commander1, Y. Hou2, J. Konen1, S. Wilkinson1, M. Gilbert-Ross3, L. Cooper2, A.I. Marcus3; 1Cancer Biology, Emory University, Atlanta, GA, 2Biomedical Informatics, Emory University, Atlanta, GA, 3 Hematology and Medical Oncology, Emory University, Atlanta, GA B539/P313 Beyond EMT: vimentin function in lung cancer metastasis. A.M. Salgueiro1, L.S. Havel1, J. Shupe1, A.E. Koyen1, H.E. Grossniklaus1, G. Sica1, M. Gilbert-Ross1, A.I. Marcus1; 1Hematology and Medical Oncology, Emory University, Atlanta, GA B540/P314 Contributions of LIM Kinase 1 and 2 to invasive motility in glioblastoma. J. Chen1, B. Ananthanarayanan1, S. Kumar1,2; 1Department of Bioengineering, UC Berkeley, Berkeley, CA, 2Department of Chemical and Biomolecular Engineering, UC Berkeley, Berkeley, CA B541/P315 Netrin-1 induced activation of Notch signaling regulates the motility of glioblastoma cells. I. Ylivinkka1,2, Y. Hu1, H. Sihto1, O. Tynninen2,3, P. Chen4, S. Hautaniemi4, T. Nyman5, P. Laakkonen1, J.K. Keski-Oja1,2; 1Translational Cancer Biology Research Program, University of Helsinki, Helsinki, Finland, 2The Hospital District of Helsinki and Uusimaa, Helsinki, Finland, 3Department of Pathology, Haartman Institute, University of Helsinki and Huslab, Helsinki, Finland, 4Institute of Biomedicine and Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland, 5Research Program in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, Helsinki, Finland B542/P316 Functional assessment of Von Willebrand Factor expression by cancer cells of non-endothelial origin. A. Mojiri1, K. Stoletov1, L. Willetts1, M. Lorenzana Carrillo1, R. Godbout1, P. Jurasz1, C. Sergi1, D. Eisenstat1, J. Lewis1, N. Jahroudi1; 1Medicine, University of Alberta, Edmonton, AB B543/P317 AMPKα2 enhances cell adhesion and migration properties in breast cancer cell lines. M.M. Fox1; 1Biology, Wingate University, Wingate, NC B544/P318 The role of the ARF GEF protein IQSEC1 splicing in prostate cancer invasion. M. Nacke1,2, E. Sandilands1,2, A. Roman-Fernandez1,2, D.M. Bryant1,2; 1Beatson Institute for Cancer Research, Glasgow, United Kingdom, 2 University of Glasgow, Glasgow, United Kingdom B545/P319 Sustained cell blebbing for entotic cell-in-cell invasion requires dynamic MRTF-dependent Ezrin regulation. L. Soto1, M. Holst1, C. Baarlink1, R. Grosse1; 1Pharmacology, University of Marburg, Marburg, Germany

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Sunday Poster Session B546/P320 Basal extrusion of KRasG12V cells is sufficient to drive their invasion from zebrafish epidermis. G. Slattum1,2, J. Fadul1, D. Hedeen1, A. Gardner1, N. Redd1, G.T. Eisenhoffer1,3, J. Rosenblatt1; 1Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 2 Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 3 Department of Genetics, MD Anderson Cancer Center, Houston, TX B547/P321 The carbonic anhydrase IX interactome reveals a critical role in invadopodia/ matrix metalloprotease 14-mediated tumor cell invasion. M. Swayampakula1, P.C. McDonald1, M. Vallejo1,2, É. Coyaud3, S.C. Chafe1, A. Westerback1, J. Shankar4, E.M. Laurent3, Y. Lou1, K.L. Bennewith1, C.T. Supuran5, I.R. Nabi4, B. Raught3, S. Dedhar1,2; 1Department of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, 2 Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, 3Princess Margaret Cancer Centre, Toronto, ON, 4Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, 5Laboratorio di Chimica Bioinorganica, Universita degli Studi di Firenze, Florence, Italy B548/P322 GALA a new pathway regulating protein glycosylation and tumor development. F.A. Bard1; 1IMCB, A*STAR, Singapore, Singapore

Tumor Microenvironment 1 B549/P323 Cellular Neighborhood Influences the Equilibria of Phenotypic States in a Heterogeneous Population. C. Krishnamurthy1, A. Paulson2, Z.J. Gartner1; 1Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, 2Biomedical Sciences Program, University of California, San Francisco, San Francisco, CA B550/P324 Schwann cells activated by cancer cells induce cancer cell invasion. S... Deborde1, T.A. Omelchenko2, A. Lyubchik1, Y. Zhou1, S. He1, W. McNamara1, N. Chernichenko1, S. Lee1, C. Chen1, R. Bakst1, E. Vakiani1, S. He1, A. Hall2, R.J. Wong1; 1Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 2Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY B551/P325 WDR4-driven PML destruction fosters immunosuppressive and prometastatic lung tumor microenvironment. Y. Wang1, R. Chen1; 1Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan B552/P326 Macrophage-dependent cytoplasmic transfer drives melanoma metastasis in vivo. M. Roh-Johnson1, A.N. Shah1, R.E. Hernandez2, C.B. Moens1; 1Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 2 Pediatric Infectious Disease, Seattle Children’s Hospital, Seattle, WA

B553/P327 Macrophage vitamin-D receptor contributes to host defense against the growth of prostate cancer. S. YasminKarim1, Y. Lee2, W. Ngwa1; 1Radiation Oncology, Harvard Medical School, Boston, MA, 2Department of Urology, University of Rochester, Rochester, NY B554/P328 Suppression of ELK3 disturbs expression of cytokines related to the lymphangiogenesis in MDA-MB-231. N. Oh1, K. Park1; 1Biomedical Science, Cha University, Seong-Nam si, Korea, South B555/P329 The expression of ELK3 in the lymphatic endothelial cells is associated with the metastasis of breast cancer. J. Park1, K. Park1; 1Biomedical Science, Cha University, SeongNam Si, Korea, South B556/P330 Transcriptional complex composed of ER(α), GATA3, FOXA1 and Ell3 regulates IL-20 expression in breast cancer cells. J. Lee1, K. Park1; 1Biomedical Science, CHA University, Sung-Nam si, Korea, South B557/P331 NF-κB signaling regulates cell-autonomous regulation of CXCL10 in breast cancer 4T1 cells. W.J. Jin1, B. Kim1, H. Kim1, J. Kim2, Z.H. Lee1; 1Cell and Developmental Biology, Seoul National University, School of Dentistry, Seoul, Korea, 2Pediatric Dentistry, Seoul National University, School of Dentistry, Seoul, Korea B558/P332 An integrated platform for real-time dynamic culturing and analysis of hypoxia with single cell resolution. A.J. Cappione1; 1RD - Applications, MilliporeSigma, Danvers, MA B559/P333 Hypoxia and pressure induce prostate androgen receptor (AR) variant expression and contribute to development of castration-resistant metastatic prostate cancer. Y. Li1, B. Adams1, T. Chow1, L. Cassereau1, B. Downey1, J. Lim1; 1Xcell Biosciences Inc., San Francisco, CA B560/P334 Mechanisms of transcriptional regulation under oxidative stress, a job for the nuclear structural protein NuMA. S. Chittiboyina1, S. Jayaraman1, P.C. Abad1, K.B. Hodges1, J. Galan2, W.A. Tao2, S.A. Lelievre1; 1Department of Basic Medical Sciences, Purdue University, West Lafayette, IN, 2Department of Biochemistry, Purdue University, West Lafayette, IN B561/P335 Metformin enhanced chemoresistance of human malignant mesothelioma cells cultured in glucose deprived media. S. Hwang1, Y. Kim1; 1Clinical pathology, Seoul national university, Seoul, Korea, South B562/P336 The role of TSAP6 in exosome secretion in ovarian carcinoma. E.C. Broner1, C.G. Trope2, B. Davidson2,3, T. Tavor Re’em 4, R. Reich1; 1Institute of Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel, 2The Medical Faculty, University of Oslo, Oslo, Norway, 3Department of Pathology, Norwegian Radium Hospital, Oslo, Norway, 4 Pharmaceutical Engineering, Azrieli – College of Engineering, Jerusalem, Israel

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B563/P337 Exosomal NM23 Mediates Purinergic Regulation of Breast Cancer Angiogenesis. S. Nordmeier1, S. Duan1, I.L. Buxton1; 1Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV

B565/P339 Specific exosome subtypes are generated in different endosomal compartments and selectively regulated by stress sensor mTORC1. S. Fan1, S.M. Perera1, B. Kroeger1, C. Alves1, I. Stefana1, J.F. Morris1, C. Wilson1, A.L. Harris2, D. Goberahan1; 1Department of Physiology, Anatomy and Genetics, Oxford University, Oxford, United Kingdom, 2The Weatherall Institute of Molecular Medicine, Oxford University, Oxford, United Kingdom B566/P340 Exploring the role of microenvironmental fatty acids in prostate cancer metastasis. W.A. Hofmann1, I.V. Maly1; 1Physiology and Biophysics, University at Buffalo-SUNY, Buffalo, NY B567/P341 The Microfluidic Intravital Window – an enabling technology for stable in vivo imaging and tumor microenvironment control. L. Butt1, L. Sfakis1, M. Strohmayer1, T. Masiello1, A. Dhall1, M. Hemachandra1, S. Voiculescu2, J. Pastoriza2, Y. Wang3,4,5, D. Entenberg3,4,5, J.S. Condeelis3,4,5, J. Castracane1; 1Nanobioscience, SUNY Polytechnic Institute, Albany, NY, 25Department of Surgery, Albert Einstein College of Medicine, Bronx, NY, 3 Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, 4Integrated Imaging Program, Albert Einstein College of Medicine, Bronx, NY, 5Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY

Regulatory and Non-Coding RNAs B900/P342 The bidirectional promoter of CatSper1 regulates a new lncRNA. S.E. Jimenez1, J. Hernandez1, N.A. Oviedo2; 1Genetics and Molecular Biology, Cinvestav, Mexico City, Mexico, 2Unidad de Investigación Médica en Inmunología e Infectologia, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico

B901/P343 Probing the Role of a Highly Expressed Long Non-Coding RNA in Hepatocellular Carcinoma. A.T. Yu1,2, J.H. Bergmann1, C. Berasain3, F. Rigo4, D.L. Spector1,2; 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 2Molecular Genetics Microbiology, Stony Brook University, Stony Brook, NY, 3Gene Therapy and Hepatology, University of Navarra, Pamplona, Spain, 4 Ionis Pharmaceuticals, Carlsbad, CA B902/P344 microRNA regulation of Kupffer cell activation during alcoholic liver injury. K. Mcdaniel1,2, H.L. Francis1,2, S.S. Glaser1,2, G. Alpini1,2, F. Meng1,2; 1Central Texas Veteran Healthcare System, Temple, TX, 2Digestive Disease Research Center, Baylor Scott White Healthcare, Texas AM HSC College of Medicine, Temple, TX B903/P345 MicroRNA changes throughout the maternal to zygotic transition in bovine in vitro fertilized embryos. J.M. Cuthbert1, K.L. White1,2, Q. Meng1, A.D. Benninghoff1,2; 1Animal Dairy and Veterinary Sciences, Utah State University, Logan, UT, 2 School of Veterinary Medicine, Utah State University, Logan, UT B904/P346 Vascular Epigenetics by Regulatory Noncoding RNA [Angiotropin & microRNA]: Epigraphic Structure Relations in Angio- and Arteriogenesis Factors Wake up Genomic “Sleeping Beauty” [Dornroeschen]. J.H. Wissler1, D.S. Dohle2, E. Logemann1; 1ARCONS Inst. Applied Research Didactics POB1327, 61231 Bad Nauheim jhw@arcons-research. de, Germany, 2Clinics for Thoracic- and Cardiovascular Surgery, Room 2-86, Universitätsklinikum Westdeutsches Herzzentrum, D- 45147 Essen, Hufelandstr.55, Germany B905/P347 Investigation of MicroRNA Expression Profiles in the Susceptible Population to In-stent Restenosis. C. Chen1,2, C. Wu1; 1College of Pharmacy, Taipei Medical University, Taipei, Taiwan, 2 Department of Pharmacy, Taipei Medical University Hospital, Taipei, Taiwan B906/P348 An unbiased shRNA-based genetic screen reveals disease mechanisms associated with GGGGCC expression and potential overlap with TDP-43. L.D. Goodman1, Y. Zhu2, M. Lan2, D.P. Cerza2, N.M. Bonini2; 1Neuroscience Graduate Group, University of Pennsylvania, Philadelphia, PA, 2Department of Biology, University of Pennsylvania, Philadelphia, PA B907/P349 Loss of yeast Npl3 results in significantly higher TERRA levels in telomerase-null cells. M. Tingey1, B. Amos1, A. Sweetman1, J.K. Jones1, J.Y. LeeSoety1; 1Biology, Saint Joseph’s University, Philadelphia, PA B908/P350 Transgenerational gene silencing by extracellular RNA. A.M. Jose1; 1Cell Biology and Molecular Genetics, University of Maryland, College Park, MD

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B909/P351 Determination of the HTLV-1 pro-pol frameshift site RNA secondary structure. E.A. Finke1, K.D. Mouzakis1; 1Chemistry, Fort Lewis College, Durango, CO B910/P352 The ASBEL-TCF3 complex is required for the tumorigenicity of colorectal cancer cells. K. Taniue1, Y. Takeda1, T. Akiyama1; 1Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan B911/P353 Investigating the role of centromeric transcription in the maintenance of human centromeres. M.G. Olson1, D.M. Sturgill1, D. Wangsa2, T. Ried2, D. Quenet1,3, Y. Dalal1; 1Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, MD, 2 Genetics Branch, National Cancer Institute, Bethesda, MD, 3Department of Medicine, University of Vermont, Burlington, VT B912/P354 A broad role for YBX1 in defining the small non-coding RNA composition of extracellular vesicles. M.J. Shurtleff1,2, Y. Qin3, J. Yao3, M.M. Temoche-Diaz1,4, A. Lambowitz3, R.W. Schekman1,2; 1Howard Hughes Medical Institute, Berkeley, CA, 2Molecular and Cellular Biology, UC Berkeley, Berkeley, CA, 3 Institute for Cellular and Molecular Biology, University of Texas, Austin, TX, 4Plant and Microbial Biology, UC Berkeley, Berkeley, CA B913/P355 Role of microRNAs in Bone Morphogenetic Protein-Induced Dendritic Growth in Primary Rat Sympathetic Neurons. K. Pravoverov1, P.J. Lein2, V. Chandrasekaran1; 1Biology, Saint Mary’s College of CA, Moraga, CA, 2Molecular Biosciences, University of California at Davis, Davis, CA

RNA Localization, Transport, Stability, and Modification B914/P356 Quantitative image analysis of mRNA-mitochondrial distance in budding yeast reveals the mechanism of co-translational protein import into mitochondria. T. Tsuboi1, M. Viana1, E. Tutucci2, R.H. Singer2, S.M. Rafelski1; 1Department of Developmental Cell Biology, University of California, Irvine, Irvine, CA, 2Department of Anatomy Structural Biology, Albert Einstein College of Medicine, Bronx, NY B915/P357 mRNA decay is regulated via the spatial sequestration of the conserved 5´-3´ exoribonuclease Xrn1 at a specific microdomain of the yeast plasma membrane. K. Vaškovičová1, T. Awadová1, M. Opekarová1, P. Veselá1, M. Balážová2, J. Malinsky1; 1Microscopy Unit, Institute of Experimental Medicine CAS, Prague, Czech Republic, 2Department of Membrane Biochemistry, Institute of Animal Biochemistry and Genetics SAS, Ivanka pri Dunaji, Slovakia

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SUNDAY

B564/P338 Non coding RNA expression in ovarian carcinoma. N. Filippov-Levi1, Y. Smith2, C.G. Trope3, B. Davidson3,4, R. Reich1; 1Institute of Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel, 2Genomic Data Analysis Unit, The Hebrew University of Jerusalem, Jerusalem, Israel, 3The Medical Faculty, University of Oslo, Oslo, Norway, 4Department of Pathology, Norwegian Radium Hospital, Oslo, Norway

Sunday Poster Session

Board No./Presentation No. B916/P358 The research progress of RNA m6A modification. C. Wan1, B. Peng1; 1School of Life Sciences and Technology, Tongji University, Shanghai, China B917/P359 The effects of Dsk1 and Kic1 protein kinases on poly(A)-binding protein in mRNA export. M. Tomy1, Z. Tang1; 1W.M. Keck Science Department, Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, CA B918/P360 Spatial control of translational repression and polarized cell growth. I. Nuñez1, M. Rodriguez Pino1, C. Chen1, F. Verde1; 1Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL B919/P361 Coilp1, a pseudogene-encoded protein, contributes to the biogenesis of regulatory RNPs. A.R. Poole1, M.D. Hebert1; 1Biochemistry, University of Mississippi Medical Center, Jackson, MS B920/P362 Spatial regulation of clock associated mRNA in Neurospora crassa. B.M. Bartholomai1, A.S. Gladfelter 2 , J.J. Loros3, J.C. Dunlap1; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, 2Department of Biology, University of North Carolina, Chapel Hill, NC, 3Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH

The Nuclear Envelope and Nuclear Pore Complexes 1 B922/P363 The impact of myonuclei in neuromuscular junction development. M. Perillo1, J.P. Forero1, E.S. Folker1; 1Biology, Boston College, Boston, MA B923/P364 PKC-mediated phosphorylation of nuclear lamins at a single serine residue influences nuclear size. L.J. Edens1, D.L. Levy1; 1Molecular Biology, University of Wyoming, Laramie, WY B924/P365 3D modeling of the nucleoplasmic reticulum (NR) in mouse embryonic stem (ES) cells. K. Yi1, F. Guo1, C. Zhao1, M. McClain1, T. Parmely1; 1EM core, Stowers Institute for Medical Research, Kansas City, MO B925/P366 Phosphoinositides and their enzymes regulate interactions between nuclear envelope, cytoskeleton and chromatin. L.L. Fabian1, J.A. Brill1,2; 1Cell Biology, Hospital for Sick Children, Toronto, ON, 2Molecular Genetics, University of Toronto, Toronto, ON B926/P367 Interactions between SUN and KASH proteins in vivo during nuclear migration, nuclear anchorage, and the developmental switch between moving and stationary nuclei. N. Cain1, D.A. Starr1; 1Molecular and Cellular Biology, University of California, Davis, Davis, CA

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Sunday Poster Session B927/P368 A Novel KASH-LESS Variant of Nesprin1 Forms Long Filaments that Associate with the Rootletin Network of Mouse Photoreceptors. C. Potter1, W. Zhu1, A. Kolesnikov1, V. Kefalov1, T. Doggett1, E. Betleja2, M.R. Mahjoub2, D. Hodzic1; 1Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO, 2 Department of Medicine, Renal Division, Washington University School of Medicine, St Louis, MO B928/P369 Metaphase chromosome alignment dictates nuclear envelope disassembly in C. elegans zygote. M.M. Rahman1, O. Cohen-Fix1; 1LCMB, NIDDK, Bethesda, MD B929/P370 Chromatin organization and replication in mature striated muscle rely on mechanical coupling through intact LINC-complex. S. Wang1, U. C. P.1, K. Fridman1, B. Markus2, T. Volk1; 1Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel, 2G-INCPM / Mantoux Institute for Bioinformatics, Weizmann Institute of Science, Rehovot, Israel B930/P371 Expression of LeukemiaAssociated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype. B. Fahrenkrog1, N. Martins1, A. Mendes1, N. Nilles1, V. Martinelli1, G. Fruhmann2, J. Schwaller2; 1Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, Gosselies, Belgium, 2 Department of Biomedicine, University Children’s Hospital, Basel, Switzerland B931/P372 Nucleus-nucleus interactions are regulated by two distinct genes linked to Emery-Dreifuss Muscular Dystrophy and Centronuclear Myopathy. M.A. Collins1, T.R. Mandigo1, J.M. Camuglia1, E.S. Folker1; 1Department of Biology, Boston College, Chestnut Hill, MA B932/P373 Mechanical LINC between nucleus and cytoskeleton regulates βcatenin nuclear access. G. Uzer1,2, G. Bas1, B. Sen2, J. Rubin2; 1Department of Mechanical Biomedical Engineering, Boise State University, Boise, ID, 2Medicine, University of North Carolina, Chapel Hill, Chapel Hill, NC B933/P374 Interaction of nesprin-2 with both actin and microtubules is required for efficient collective, but not single cell migration. R. Zhu1,2, S. Antoku2, G.G. Gundersen2; 1Integrated Program in Cellular, Molecular and Biomedical Studies, Columbia University, New York, NY, 2 Department of Pathology and Cell Biology, Columbia University, New York, NY B934/P375 ESCRT-III proteins CHMP7 and CHMP4B mediate nuclear membrane repair during interphase. P. Isermann1, C.M. Denais1, R.M. Gilbert1, J. Lammerding1; 1Weill Institute for Cell and Molecular Biology Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY

B935/P376 ESCRT III Repairs Nuclear Envelope Rupture During Confined Cell Migration to Limit DNA Damage and Cell Death. M. Raab1, M. Gentili2, H. De Belly1, H.R. Thiam1, R. Attia1, P. Vargas1, F. Lautenschlaeger1, R. Voituriez3, A. Jimenez1, A. Lennon-Dumenil2, N. Manel2, M. Piel1; 1Subcellular Structure and cellular Dynamics, Institut Curie, Paris, France, 2 Immunology and Cancer, Institut Curie, Paris, France, 3Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France B936/P377 Differential SUN protein oligomerization in living cells revealed by fluorescence fluctuation spectroscopy and brightness analysis. C.A. Saunders1, J. Hennen2, Z. Jahed3, B. Burke4, M. Mofrad3, J.D. Mueller2, G. Luxton1; 1Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, 2Physics and Astronomy, University of Minnesota, Minneapolis, MN, 3 Bioengineering, University of California, Berkeley, Berkeley, CA, 4Institute of Medical Biology, A-Star, Singapore, Singapore B937/P378 Using microfluidic encapsulation of Xenopus laevis embryonic cytoplasm to identify nuclear size scaling mechanisms. P. Chen1, D.L. Levy2, J.S. Oakey2, D.L. Levy1; 1Department of Molecular Biology, University of Wyoming, Laramie, WY, 2Department of Chemical Engineering, University of Wyoming, Laramie, WY B938/P379 The role of Jaw1 in maintaining nuclear shape. T. Kozono1, K. Tadahira2, M. Nakano3, T. Dohi3, T. Tonozuka2, A. Nishikawa2; 1Dep. FESS., Tokyo University of Agriculture and Technology, Tokyo, Japan, 2 Dep. Appl. Biol. Sci., Tokyo University of Agriculture and Technology, Tokyo, Japan, 3 Res. Inst., National Center for Global Health and Medicine, Tokyo, Japan B939/P380 When size matters: Regulation of the nuclear size by DHRS7 in prostate cancer. A. Rizzotto1, E. Schirmer1; 1Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom B940/P381 Samp1, a RanGTP binding transmembrane protein in the inner nuclear membrane. B. Vijayaraghavan1, M. Jaffer Ali1, R.A. Figueroa1, E. Hallberg1; 1Department of Neurochemistry, Stockholm University, Stockholm, Sweden B941/P382 Mechanical control of nuclear blebbing and micronuclei in hepatocellular carcinoma cells. K. Mandal1, R.G. Wells2, P.A. Janmey1; 1Institute for Medicine and Engineering, Pennsylvania University, Philadelphia, PA, 2Gastroenterology, and Pathology and Laboratory Medic, Pennsylvania University, Philadelphia, PA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Endocytic Trafficking 1 B943/P383 The post-translational modification of microtubules mediates receptor signaling. M. Kobayashi1, Y. Suzuki1, Y. Sato1; 1Department of Vascular Biology, IDAC, Tohoku University, Sendai, Miyagi, Japan

B945/P385 Nonmuscle Myosin II regulates membrane dynamics of endocytic proteins and receptor-ligand complex during clathrin mediated endocytosis in epithelial cells. K.L. Otterpohl1, S.B. Ortmeier1, R.G. Hart1, J. Liu2, I. Chandrasekar1,3; 1Children’s Health Research Center, Sanford Research, Sioux Falls, SD, 2Department of Nanoscience and Nanoengineering, South Dakota School of Mines and Technology, Rapid City, SD, 3 Department of Pediatrics, USD Sanford School of Medicine, Sioux Falls, SD B946/P386 Actin- and microtubulebased motors contribute to clathrinindependent endocytosis in yeast. D.C. Prosser1, T.K. Woodard1, B. Wendland1; 1Biology, The Johns Hopkins University, Baltimore, MD B947/P387 Molecular mechanisms of ATPstimulated Pannexin 1 internalization. A.K. Boyce1, L.A. Swayne1; 1Division of Medical Sciences, University of Victoria, Victoria, BC B948/P388 Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling through recruiting RabGAP1L to early endosomes. F. Qu1,2, D. Lorenzo1,2, S.J. King1,3, R. Brooks1,3, J.E. Bear1,3, V. Bennett1,2; 1Howard Hughes Medical Institute, Chevy Chase, MD, 2Biochemistry and Cell Biology, Duke University, Durham, NC, 3Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC B949/P389 Reconstitution of endocytic actin networks on supported lipid bilayers. E.H. Stoops1, M. Wojcik2, S. Low-Nam2, J.T. Groves2, K. Xu2, D.G. Drubin1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Chemistry, University of California, Berkeley, Berkeley, CA B950/P390 Characterization of the Dynamic Clathrin-Coated Pit Proteome. M. DeNies1, A. Nesvizhskii2,3, S. Schnell2,4, A.P. Liu5,6; 1Cell and Molecular Biology Graduate Program, University of Michigan, Ann Arbor, MI, 2Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 3Department of Pathology,

University of Michigan, Ann Arbor, MI, Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 5Mechanical Engineering, University of Michigan, Ann Arbor, MI, 6 Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 4

B951/P391 High-throughput superresolution imaging of clathrinand actin-mediated endocytosis in yeast. M. Mund1, A. Picco2, M. Kaksonen2, J. Ries1; 1Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany, 2Department of Biochemistry, University of Geneva, Geneva, Switzerland B952/P392 Reprogramming of clathrinmediated endocytosis dynamics during cellular differentiation. D. Dambournet1, S. Hong1, M.S. Akamatsu1, A.T. Cheng1, D. Hockemeyer1, D.G. Drubin1; 1MCB, UC Berkeley, Berkeley, CA B953/P393 Vps4 is required for clathrinmediated endocytosis mutant viability and cargo trafficking from the plasma membrane. K. Hoban1, S. Lux1, J. Poprawski1, Y. Zhang1, D.C. Prosser1, C. Norris1, B. Wendland1; 1Department of Biology, Johns Hopkins University, Baltimore, MD B954/P394 Multisite phosphorylation of Dynamin 1 functions at the crossroads of endocytosis and receptor mediated signaling pathways. S. Srinivasan1, C.J. Burckhardt1, P. Chen1, N. Bendris1, C.R. Reis1, M. Mettlen1, G. Danuser1, S.L. Schmid1; 1Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX B955/P395 Distinct regulation of EGFR and ErbB2 signaling by clathrin coated pits. J. Abousawan1, K. Patel1, S. Lucarelli1, C.N. Antonescu1; 1Chemistry and Biology, Ryerson University, Toronto, ON B956/P396 Selective regulation of EGFR signaling and endocytosis by phospholipase C and calcium. R.C. Delos Santos1, S. Bautista1, L.N. Bone1, R.M. Dayam1, R.J. Botelho1, C.N. Antonescu1,2; 1Chemistry and Biology, Ryerson University, Toronto, ON, 2Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, Toronto, ON B957/P397 The Retromer Complex Regulates APP Trafficking & Synaptic Growth at the Drosophila NMJ. R.B. Walsh1, M.A. Zunitch1, A.N. Becalska1, J. Gittzus1, A.A. Rodal1; 1Biology, Brandeis University, Waltham, MA B958/P398 Acute increase of α-synuclein dimers inhibits synaptic vesicle endocytosis at a vertebrate central synapse. A.T. Medeiros1, L. Soll1, I. Tessari2, L. Bubacco2, J.R. Morgan1; 1Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA, 2Department of Biology, University of Padova, Padova, Italy

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B959/P399 Disease-associated α-synuclein splice variant 112 exhibits enhanced binding to phospholipids. L. Soll1, J.R. Morgan1; 1Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA B960/P400 Molecular Investigations Into the Presynaptic Functions of Synucleins. K.J. Vargas1,2, N. Schrod3, T. Davis1,2, R. Fernandez-Busnadiego2,4,5, Y.V. Taguchi2,4, U. Laugks3, V. Lucic3, S.S. Chandra1,2,6; 1Department of Neurology, Yale University, New Haven, CT, 2Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University, New Haven, CT, 3Max Planck Institute of Biochemistry, Martinsried, CT, 4Department of Cell Biology, Yale University, New Haven, CT, 5 Howard Hughes Medical Institute, Yale University, New Haven, CT, 6Department of Neuroscience, Yale University, New Haven, CT B961/P401 Neuron-enriched endosomal protein of 21kD (NEEP21) is a type II transmembrane protein. B. Comuzzi1, F. Zahra1, C. Yap2, B. Winckler2, E. Norstrom1; 1Biological Sciences, DePaul University, Chicago, IL, 2Cell Biology, University of Virginia, Charlottesville, VA B962/P402 Identification of Novel Regulators of ß1-integrin Endocytosis. P. Sahgal1, A. Arjonen1, J.H. Alanko1, M. Pietilä1, J. Ivaska1; 1Turku Centre for Biotechnology, University of Turku, Turku, Finland B963/P403 Cargo induced recruitment of endocytic adaptor Sla1 and the role of Sla1-Clathrin binding in endocytic progression. T.O. Tolsma1, L.M. Cuevas1, S.M. Di Pietro1; 1Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B964/P404 Catching the tubule – Analyzing the role of the PtdIns3P-binding protein WDFY2 in retrograde endocytic transport. M. Sneeggen1,2, K.O. Schink1,2, E.M. Haugsten1,2, N.M. Pedersen1,2, C. Campsteijn1,2, H. Stenmark1,2; 1Centre for Cancer Biomedicine, Faculty of Medicine, Oslo, Norway, 2Department of Molecular Cell Biology, Institute for Cancer Research, Oslo, Norway B965/P405 Genetic dissection of early endosomal recycling highlights a TORC1independent role for Rag GTPases. C. MacDonald1, R. Piper1; 1Molecular Physiology & Biophysics, University of Iowa, Iowa City, IA B966/P406 Pro-inflammatory cytokines and oxide nitric production in murine macrophage J774A.1 cell line during the internalization of outer membrane vesicles (OMV) from Escherichia coli JC8031. A.F. Buitrago1,2, A.F. Leal1,3, A.L. Muñoz1, J.D. Valderrama1, M.E. Forero1; 1Universidad Antonio Nariño, Bogota D.C, Colombia, 2Universidad El Bosque, Bogota D.C, Colombia, 3 Universidad Nacional de Colombia, Bogota D.C, Colombia

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SUNDAY

B944/P384 Novel motor-independent function of the dynein light chain in clathrin mediated endocytosis. K.B. Farrell1, S. McDonald1, C. Worcester1, O.B. Peersen1, S.M. Di Pietro1; 1Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO

Sunday Poster Session

Board No./Presentation No. B967/P407 Monoubiquitination of syntaxin 3 leads to targeting into the apical endosomal/exosomal pathway: role in cargo recruitment. A.J. Giovannone1, E. Reales-Rodriguez2, P. Bhattaram3, A. FraileRamos4, T. Weimbs1; 1Molecular, Cellular, Developmental Bio., University of California, Santa Barbara, Santa Barbara, CA, 2 Department of Cell Biology, Yale School of Medicine, New Haven, CT, 3Department of Cell Biology, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, 4Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Madrid, Spain B968/P408 Regulation of membrane trafficking during glucose starvation. H. Hong1, J.Y. Martinez-Marquez2, L. Gal3, M. Schuldiner3, M.C. Duncan1,2; 1Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, 2Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 3Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel B969/P409 Cell adhesion changes the localization of Lyn tyrosine kinase. T. Morinaga1,2, N. Yamaguchi2, M. Tagawa1, N. Yamaguchi2; 1Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan, 2Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan B970/P410 Annexin A2 facilitates endocytic trafficking of antisense oligonucleotides. S. Wang1, H. Sun1, M. Tanowitz1, S.T. Crooke1, X. Liang1; 1Core research, Ionis Pharmaceuticals, Carlsbad, CA B971/P411 Quantitative analysis of endocytic protein accumulation during mammalian clathrin-mediated endocytosis. M. Akamatsu1, D.G. Drubin1; 1Molecular and Cellular Biology, University of California, Berkeley, Berkeley, CA

ER and Golgi Transport B972/P412 TRAPPC11 mutations lead to a diverse set of disorders with muscular dystrophy as a common feature. M. Sacher1,2, M.P. Milev1, K. Prematilake1, A. Larson3, S. Moore4, K. Köhler5, A. Hübner5, C. Jimenez-Mallabrera6; 1Biology, Concordia University, Montreal, QC, 2Anatomy and Cell Biology, McGill University, Montreal, QC, 3 Pediatrics, Children’s Hospital of Colorado, Aurora, CO, 4Pathology, University of Iowa, Iowa City, IA, 5Children, Dresden University of Technology, Dresden, Germany, 6 Neuromuscular Unit, Hospital Sant Joan de Déu, Barcelona, Spain

 22

Sunday Poster Session B973/P413 Tango1 increases general secretory capacity in Drosophila by maintaining size of ER exit sites and proximity to Golgi. M. Liu1, Z. Feng1, H. Ke1, Y. Liu1, W. Cui1, T. Sun1, J. Dai1, J.C. Pastor-Pareja1; 1School of Life Sciences, Tsinghua University, Beijing, China B974/P414 Regulation of COPII vesicle trafficking by O-GlcNAcylation. B.J. Bisnett1, N.J. Cox1,2, B.M. Condon1,2, T.R. Meister1, T.J. Smith1, M. Boyce1; 1Biochemistry, Duke University, Durham, NC, 2Pharmacology and Cancer Biology, Duke University, Durham, NC B975/P415 COPII sorts cargo into spatially distinct ER domains prior to fission of Golgi-bound transport carriers. O. Shorn1, I. Nevo-Yassaf1, T. Aviad1, J. Shepchelovich1, E. Perlson2, G.H. Patterson3, C. Kaether4, K. Hirschberg1; 1Pathology, Tel-Aviv University Sackler School of Medicine, Tel Aviv, Israel, 2 Physiology and Pharmacology, Tel-Aviv University Sackler School of Medicine, Tel Aviv, Israel, 3Section on Biophotonics, NIBIB, National Institutes of Health, Rockville, MD, 4 Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany B976/P416 Sphingomyelin organization controls the shape and function of the Golgi membranes. F. Campelo1, J. van Galen2,3, V. Malhotra2,3,4, M. GarciaParajo1,4; 1ICFO-Institut de Ciencies Fotoniques, Castelldefels, Barcelona, Spain, 2 Cell and Developmental Biology, Centre for Genomic Regulation (CRG), Barcelona, Spain, 3Universitat Pompeu Fabra, Barcelona, Spain, 4Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain B977/P417 Localization of golgin-160 at the Golgi is dynamic. C.E. Gilbert1, E. Sztul2, C.E. Machamer1; 1Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD, 2Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham School of Medicine, Birmingham, AL B978/P418 The Arf-GEFs Gea1 and Gea2 use auto-regulation and protein interactions to make decisions about initiating vesicle formation at the Golgi complex. M.A. Gustafson1, J.C. Fromme1; 1MBG/WICMB, Cornell University, Ithaca, NY B979/P419 Morphology and Protein Composition of the GLUT4 Perinuclear Sorting Compartment in InsulinResponsive Cell Types Affects the Kinetics of GLUT4 Trafficking. A. Brumfield1, N. Chaudhary1, D. Molle1, T.E. McGraw1; 1Biochemistry, Weill Cornell Medical College, New York, NY

B980/P420 Deletion of the Conserved Oligomeric Golgi subunits impairs protein trafficking and results in dramatically enlarged endosomal/ lysosomal compartments. J.B. Blackburn1, I.D. Pokrovskaya1, P. Fisher2, D. Ungar2, V.V. Lupashin1; 1Cellular Physiology, University of Arkansas for medical sciences, Little Rock, AR, 2Department of Biology, University of York, York, United Kingdom B981/P421 Multiple ER / Golgi SNARE transmembrane domains are dispensable for trafficking but required for SNARE recycling. L. Chen1, S. Lau1, D.K. Banfield1; 1Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong B982/P422 A regulatable secretory cargo for yeast. J.C. Casler1, E. Papanikou1, J.J. Barrero1, I. Fitzgerald1, B.S. Glick1; 1Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL B983/P423 Novel interactions of clathrin adaptors at the TGN in yeast. J.Y. Martinez-Marquez1, M.C. Duncan1; 1Cell and Developmental Biology, University of Michigan, Ann Arbor, MI B984/P424 Thrombospondin 4 reduces amyloid deposition in a mouse model of Alzheimer’s disease. M. Maillet1, J.D. Molkentin1; 1Molecular Cardiovascular Biology, Cincinnati Children’s Hospital, Cincinnati, OH B985/P425 Analysis of GOLPH3 knockingdown on protein glycosylation, trafficking and function in cells T98G of glioblastoma multiforme. C.L. Arriagada Momberg1, V. Cavieres1, A. Gonzalez1, P.V. Burgos1, G.A. Mardones1; 1Department of Physiology, Universidad Austral de Chile, Valdivia, Chile B986/P426 Unraveling the mechanism of ER-associated organelle fission. G. Voeltz1, M. Phillips1, P.J. Chitwood1; 1MCD Biology, University of Colorado, Boulder, CO B987/P427 ACBD3 facilitates Golgi retention of KDELR and regulates its retrograde transport. Y. Qian1, X. Yue1, M. Bao1, S. Li1, I. Lee1; 1SIAIS, Shanghai Tech University, Shanghai, China B988/P428 Neurodegeneration-associated TREM2 mutants abortively cycle between the ER and Golgi. D.W. Sirkis1, R.E. Aparicio1, R.W. Schekman1; 1Molecular and Cell Biology, UC Berkeley, Berkeley, CA B989/P429 Procollagen I exits the endoplasmic reticulum in large COPII coated vesicles. L. Yuan1, A. Gorur1, S.J. Kenny2, S. Baba1, K. Xu2, R.W. Schekman1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Chemistry, University of California, Berkeley, Berkeley, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1000/P430 Lack of N-glycosylation of Pannexin 2 triggers aggregation in the endoplasmic reticulum without ablating its capacity to traffic to the cell surface. R.E. Sánchez-Pupo1, D. Johnston1, S. Penuela1; 1Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON

B1007/P437 Rab17 sumoylation and GTPase activity regulate at least two steps in hepatic transcytosis. A.C. Striz1, P.L. Tuma1; 1Biology, The Catholic University of America, Washington, DC B1008/P438 Modularity of Exocytic Trafficking Conferred by a Rab GEF and GAP Regulatory Loop. B. Wu1, A. Ghosh2, R. Radhakrishnan2, W. Guo1; 1Biology, University of Pennsylvania, Philadelphia, PA, 2 Bioengineering, University of Pennsylvania, Philadelphia, PA

Rab GTPases

B1009/P439 Intersectin couples endoand exocytosis of epidermal growth factor receptor through DENND2B. M.S. Ioannou1, J.J. Morein1, M. Fotouhi1, S. Tse1, N. Nossova1, G. Kulasekaran1, T. Han1, E. Mannard1, P.S. McPherson1; 1Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC

B1002/P432 Rab6 Prevents the Stalling of Cargo Protein Transport Between Medial and Trans Golgi Cisternae. L. Dickson1, S. Liu1, E. Islek1, B. Storrie1; 1Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR

B1010/P440 The recruitment and activation of a Rab GTPase in lysosome-related organelle biogenesis. G.J. Hermann1, O. Foster1, K. Peloza1, L. Harper1, J. Brandt1, M. Harp1, C. Morris1; 1Biology, Lewis Clark College, Portland, OR

B1003/P433 The role of phosphorylation on the function of Rab7. O. Skorobogata1, G. Modica1, S. Lefrancois1,2; 1Institut nationale de la recherche scientifique – Institut Armand-Frappier, Laval, QC, 2Department of Anatomy and Cell Biology, McGill University, Montreal, QC

B1011/P441 Rabomic analysis of membrane traffic of G protein-coupled receptors. C. Li1, W. Huang1, G. Wu1; 1Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA

B1004/P434 Cdk5-dependent phosphorylation of GRAB, a guanine nucleotide exchange factor for Rab8, regulates axon outgrowth by directing Rab8A to Rab11A-positive endosomes. K. Furusawa1, A. Asada1, P. Urrutia2,3, C. Gonzalez-Billaul2,3, M. Fukuda4, S. Hisanaga1; 1Biological Sciences, Tokyo Metropolitan University, Hachioji, Japan, 2 Biology, Universidad de Chile, Nunoa, Chile, 3Geroscience Center for Brain Health and Metabolism, Santiago, Chile, 4 Developmental Biology and Neurosciences, Tohoku University, Sendai, Japan B1005/P435 A Novel and Direct Interaction Between Large and Small GTPases: A Rab10-Dynamin-2 Complex Mediates Autophagic Lipid Droplet Breakdown. Z. Li1,2,3, K. Drizyte1,2,3, C.A. Casey4, M.A. McNiven1,3; 1Center for Digestive Diseases, Mayo Clinic, Rochester, MN, 2Biochemistry and Molecular Biology Program, Mayo Graduate School, Rochester, MN, 3 Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, 4 Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE B1006/P436 The GTPase, RAB-10, regulates the dynamics of autophagy. N.J. Palmisano1, A. Melendez1, B. Grant2; 1Biology, The Graduate Center, City University of New York, New York, NY, 2Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ

B1012/P442 RAB27B requirement for stretch-regulated exocytosis in bladder umbrella cells. M.G. Dalghi1, L. Gallo1, D.R. Clayton1, W.G. Ruiz1, P. Khandelwal1, G. Apodaca1; 1Department of Medicine, RenalElectrolyte Division, University of Pittsburgh, Pittsburgh, PA B1013/P443 Regulation of iPLA2 Activity and Localization by Rab5. Y. Shi1, D. Chung2, C.Y. Chung1,2; 1School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China, 2 Pharmacology, Vanderbilt University School of Medicine, Nashville, United States B1014/P444 TRAPPIII functions at the Golgi complex and in autophagy. A. Joiner1, L. Thomas1, J.C. Fromme1; 1Molecular Biology and Genetics, Cornell University, Ithaca, NY

Cell Signaling and Polarity B1016/P445 The developmental polarity and morphogenesis of a single cell. D. Bonazzi1, A. Haupt2, J. Julien3, H. Tanimoto2, R. Seddiki2, M. Romao4, D. Delacour2, D. Salort5, M. Piel4, A. Boudaoud6, N. Minc2; 1Pathogenesis of Vascular Infections, Institut Pasteur, Paris, France, 2Institut Jacques Monod, Paris, France, 3Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany, 4Institut Curie, Paris, France, 5UMR 7238 CNRS, Université Pierre et Marie Curie, Paris, France, 6ENS CNRS, Laboratoire Joliot-Curie, Lyon, France

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1017/P446 Cdc42p Localization Regulates Yeast Cell Fusion. J.A. Smtih1, M.D. Rose1; 1Molecular Biology, Princeton University, Princeton, NJ B1018/P447 Role of Cdc42 GAP Rga4 in altering the morphological fate of S. pombe daughter cells. M. Rodriguez Pino1, I. Nuñez1, M. Das2, D. Vavylonis3, F. Verde1; 1Cellular and Molecular Pharmacology, University of Miami, Miami, FL, 2Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 3Department of Physics, Lehigh University, Bethlehem, PA B1019/P448 Scaffold-mediated gating of Cdc42 signaling flux contributes to GTPase nanoclustering. D.W. McCusker1; 1IECB, Bordeaux, France B1020/P449 Cortical contractility induces clustering of PAR proteins for embryonic polarization. S. Wang1, T.Y. Low1, Y. Nishimura2, W. Yu3, F. Motegi1,2,4; 1Temasek Life-sciences Laboratory, Singapore, Singapore, 2Mechanobiology Institute, Singapore, Singapore, 3Institute of Molecular Cell Biology, A*STAR, Singapore, Singapore, 4Department of Biological Sciences, National University of Singapore, Singapore, Singapore B1021/P450 Unraveling PAR polarity protein interactions with single-cell biochemistry. D.J. Dickinson1,2, B. Goldstein1,2; 1Biology, University of North Carolina, Chapel Hill, NC, 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC B1022/P451 Nanoscopic E-Cadherin organization in Drosophila embryo is regulated by Crumbs-dependent junctional repartition of Par-3. P. Salis1, V. Aksenova1, B. Truong Quang2, P. Lenne1, T. Lecuit1, A. Le Bivic1; 1Institut de biologie du développement de Marseille (IBDM), Marseille, France, 2MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom B1023/P452 A pattern-formation mechanism that bases on mechanochemical feedback drives the dynamics of PAR polarity establishment in C. elegans zygotes. P. Gross1,2, K. Kumar3,4, J.S. Bois5, N.W. Goehring6, C. Hoege1, F. Julicher3, S.W. Grill1,2,3; 1MPICBG, Dresden, Germany, 2BIOTEC, Dresden, Germany, 3MPI-PKS, Dresden, Germany, 4ICTS, Bangalore, India, 5 Department of Chemistry and Biochemistry, UCLA, Los Angeles, United States, 6Francis Crick Institute, London, United Kingdom B1024/P453 Competition among PAR-3 clusters for cytoplasmic monomers can stabilize PAR-3 asymmetries in the absence of mutual inhibition. C.F. Lang1, A. Anneken2, E.M. Munro1,2; 1Committee on Genetics, Genomics, and Systems Biology, University of Chicago, Chicago, IL, 2Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL

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SUNDAY

B1001/P431 The role of SAR1 paralogs in packaging of large lipoprotein cargos. D.B. Melville1,2, S. Studer1, R. Schekman1,2; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Howard Hughes Medical Institute, Berkeley, CA

Sunday Poster Session

Board No./Presentation No. B1025/P454 A novel role for Cdc42 effectors Gic1/2 in cell polarity. C.N. Daniels1, D.J. Lew1; 1Molecular Cancer Biology, Duke University, Durham, NC B1026/P455 Disruption of cell polarity, but not adhesion, alters Notch-mediated proliferation and differentiation in endometrial cancer. A.B. Gladden1, E.R. Williams1, R.R. Broaddus2; 1Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 2Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX B1027/P456 Active anti-inflammatory function of normal polarized epithelia and “polarity complex” proteins. R. Forteza1, A. Mashukova2, P.J. Salas1; 1Cell Biology, Univ. of Miami Miller School of Medicine, Miami, FL, 2Physiology, Nova Southeastern University, Fort Lauderdale, FL B1028/P457 Investigating the Mechanisms of Contact Inhibition in Mammalian Epithelia. M. Fomicheva1, I.G. Macara1; 1CDB, Vanderbilt University, Nashville, TN B1029/P458 Identification of Crumbs family protein functions in MDCK cells, using CRISPR gene editing. C. Yang1, I.G. Macara1; 1Cell & Developmental Biology, Vanderbilt University, Nashville, TN B1030/P459 Defining the network of proteins driving apical-basal polarity establishment in early Drosophila development. T.T. Bonello1, M. Peifer1; 1Biology, University of North Carolina, Chapel Hill, NC B1031/P460 A novel delivery-based positive feedback loop drives epithelial apical membrane morphogenesis in Drosophila. F. Nunes de Almeida1, R.F. Walther1, E. Vlassaks1, F. Pichaud1; 1MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom B1032/P461 Substance P directly induces M2 polarization of tissue macrophage through PI3K/AKT/mTOR pathway even in the presence of IFN-gamma, distinct from IL-4/13 and IL-10-mediated M2a and M2c macrophages. J. Lim1, S. Kim1, W. Ahn1, E. Chung1, Y. Son1; 1Genetic Engineering, Kyung Hee University, Yong In, Korea, South B1033/P462 Suppressing ERK1/2 phosphorylation of TAN Line Component FHOD1 rescues defective nuclear movement in fibroblasts expressing muscular dystrophy lamin A mutants. S. Antoku1, W. Wu2, C. Östlund2, H.J. Worman2, G.G. Gundersen1; 1Department of Pathology and Cell Biology, Columbia University, New York, NY, 2Department of Medicine, Columbia University, New York, NY

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Sunday Poster Session B1034/P463 N-glycosilation of the β2subunit and the apical polarity of the sodium pump in retinal pigment epithelia. T. Lopez Murillo1, M. Roldan Gutierrez1, L. Shoshani1; 1Physiology, Cinvestav-IPN, Mexico City, Mexico

B1041/P470 Patterning the cytoplasm: the interconnected roles of PAR-1 and MEX-5. J. Smith1, A.W. Folkmann1, G. Seydoux1; 1Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine/HHMI, Baltimore, MD

B1035/P464 Epithelial Membrane Protein 2 regulates APC-mediated 3D morphogenesis and apical-basal polarity. A.C. Lesko1,2,3, C.G. Ahlers1,2, J.R. Prosperi1,2,3; 1Biochemistry and Molecular Biology, Indiana University School of Medicine-South Bend, South Bend, IN, 2Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, 3 Biological Sciences, University of Notre Dame, Notre Dame, IN

B1042/P471 Like mother, like daughter: Inheritance of growth sites determines cell shape. J. Rich1, M. Das1; 1Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN

B1036/P465 The RhoG exchange factor SGEF forms a ternary complex with two members of the SCRIBBLE polarity complex, Scribble and Dlg1. S. Awadia1, T.R. Arnold2, F. Huq2, T. Hou3, Y. Sun3, P. Massimi4, L. Banks4, E. Fuentes3, A.L. Miller2, R. Garcia-Mata1; 1Department of Biological Sciences, University of Toledo, Toledo, OH, 2Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 3 Department of Biochemistry, University of Iowa, Iowa City, IA, 4ICGEB, Trieste, Italy B1037/P466 Ezrin activation by LOK phosphorylation involves a PIP2dependent coincidence detection mechanism in a multi-step reaction. T. Pelaseyed1, R. Viswanatha1, J.J. Filter1, M.L. Goldberg1, A.P. Bretscher1; 1Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY B1038/P467 A Novel Element in the Cytoplasmic domain of the Type I TGFβ Receptor Mediates Basolateral Targeting in Polarized Epithelial Cells. X. Yin1, M. Andrianifahanana1, J. Kang1, Y. Wang2, M. Jung1, D. Hernandez1, E.B. Leof1; 1Thoracic Diseases Research Unit, Department of Pulmonary and Critical Care Medicine, Mayo Clinic Rochester, Rochester, MN, 2 Department of Medicine, Georgia Regents University, Augusta, GA B1039/P468 Dynamics of Rga1, a Cdc42 GTPase-activating protein, at the old and current cell division sites in budding yeast. K.E. Miller1, W.C. Lo2, M.E. Lee*1, H.O. Park1,3; 1Molecular Cellular Developmental Biology Program, The Ohio State University, Columbus, OH, 2 Department of Mathematics, City University of Hong Kong, Kowloon, Hong Kong, 3 Department of Molecular Genetics, The Ohio State University, Columbus, OH B1040/P469 Mating yeast cells concentrate the pheromone receptor and its G protein as polarized crescents at the default polarity site that then track to the eventual chemotropic site. X. Wang1, D.E. Stone1; 1Biological Sciences, University of Illinois at Chicago, Chicago, IL

B1043/P472 Regulation of RNA granule assembly by phosphorylation of an intrinsically-disordered protein scaffold. H. Schmidt1, D. Calidas1, D. Rasoloson1, G. Seydoux1; 1HHMI, Department of Molecular Biology & Genetics, Johns Hopkins Medical School, Baltimore, MD

Neuronal Morphogenesis and the Cytoskeleton B1045/P473 A human spinocerebellar ataxia type 5 mutation in β-III-spectrin causes high-affinity actin binding in cells and decreases dendritic arborization by reducing spectrin localization in dendrites. A.W. Avery1, M.E. Fealey2, D.D. Thomas2, T.S. Hays1; 1Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, 2Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN B1046/P474 ARFGEF2/ARF1/RhoA/mDia1 regulates dendrite development through Golgi polarization in hippocampal neurons. E. Hong1, J. Kim1, J. Kim2, D. Lim3, J. Kim1; 1Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon, Korea, South, 2Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea, South, 3 Department of Biological Sciences, KAIST, Daejeon, Korea, South B1047/P475 Adaptor complex 2 controls dendrite morphology via mTORC1dependent expression of GluA2. A. Koscielny1, A.R. Malik1, E. Liszewska1, J. Zmorzynska1, A. Tempes1, B. Tarkowski1, J. Jaworski1; 1International Institute of Molecular and Cell Biology, Warsaw, Poland B1048/P476 Kif20b: a mitotic kinesin with post-mitotic functions in neuronal polarization and axon extension. K.C. McNeely1, T.D. Cupp1, J.L. Neville1, K.M. Janisch1, N.D. Dwyer1; 1Cell Biology, University of Virginia School of Medicine, Charlottesville, VA B1049/P477 N-terminal and central domains of APC differentially and cooperatively sculpt optic axonal arbors in Xenopus tadpoles. T.M. Elul1, A. Sohal1, T. Jin1; 1Basic Sciences, COM, Touro University California, Vallejo, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1050/P478 Axonal growth and guidance responses regulated by NADPH oxidasederived reactive oxygen species. H.S. Roeder1, D.M. Suter1; 1Department of Biological Sciences, Purdue University, West Lafayette, IN

B1052/P480 TRIM9 and TRIM67: master regulators of developing and adult-born neurons. S. Menon1, E. Cousins1, B. Major1, S.L. Gupton1; 1Cell Biology and Physiology, University of North Carolina, Chapel Hill, Chapel Hill, NC

B1060/P488 Intermediate filament mediated phospho-regulation of Doublecortin during neuronal development. C.J. Bott1, C. Yap1, B. Winckler1; 1Cell Biology, University of Virginia, Charlottesville, VA

B1070/P497 Membrane binding by CHMP7 coordinates ESCRT-III dependent nuclear envelope reformation. J.G. Carlton1, Y. Olmos1, A. Perdrix-Rosell1; 1Cancer Studies, KCL, London, United Kingdom

B1061/P489 Neuronal Activity Modulates the Phosphorylation State of Tau in Dendrites, Leading to Altered Microtubule Dynamics and Changes in Synaptic Plasticity. D.P. McVicker1, E.W. Dent1; 1Neuroscience, University of Wisconsin, Madison, WI

B1071/P498 Lem2p (LEM2) and Cmp7p (CHMP7) function in ESCRT-dependent nuclear envelope remodeling in fission yeast. M. Gu1, O.S. Chen1, M.S. Ladinsky2, P.J. Bjorkman2, W.I. Sundquist1, A. Frost1,3; 1Biochemistry, University of Utah, Salt Lake City, UT, 2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 3Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA

B1062/P490 Role of MTCL1, a microtubule crosslinking and stabilizing protein, in the formation of axon initial segment. T. Satake1, A. Suzuki1; 1Molecular Cellular Biology Laboratory, Yokohama City University Graduate School of Medical Life Science, Yokohama, Japan

B1053/P481 Differentiation of Mouse Embryonic Stem Cells into Purkinje Neurons. C.J. Alexander1, J.A. Hammer1; 1CBPC, Nation Heart, Lung, and Blood Institute, Bethesda, MD

B1063/P491 14-3-3epsilon regulates neurite formation. T. Wachi-Toyooka1,2, B. Cornell1, K. Watanabe2, K. Toyooka1; 1Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 2Tokyo Nishi Tokushukai Hospital, Tokyo, Japan

B1054/P482 Functional analysis of shootin1 in neuronal migration and formation of the olfactory bulb. T. Minegishi1, Y. Uesugi1, W. Yoshida1, N. Inagaki1; 1Biological Science, Nara Institute of Science and Technology, Ikoma, Japan

B1064/P492 Monitoring Microtubule Dynamics at Synaptic Contacts in Neurons Challenged with Oligomeric Aβ1-42. X. Qu1, F. Bartolini1; 1Department of Pathology and Cell Biology, Columbia University, New York, NY

B1055/P483 Differential Expression of Piccolo Splice Isoforms During Mouse Cerebellar Development. K.J. Cruz1, S.D. Fenster1; 1Biology, Fort Lewis College, Durango, CO

B1065/P493 Formin-mediated Microtubule Hyperstabilization is Necessary for Amyloid-β Synaptotoxicity. X. Qu1, F. Yuan1, C. Corona1, S. Pasini1, M. Pero1, G.G. Gundersen1, M.L. Shelanski1, F. Bartolini1; 1Department of Pathology and Cell Biology, Columbia University, New York, NY

B1056/P484 Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina. J. Icha1, C. Grunert1, M.R. Martins1, C. Norden1; 1Norden lab, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B1057/P485 Microtubule Organization Determines Axonal Transport Dynamics. S. Yogev1, R. Cooper2, R. Fetter1, M. Horowitz3, K. Shen1; 1Department of Biology, Howard Hughes Medical Institute, Stanford, Stanford, CA, 2Department of Electrical Engineering, Stanford, Stanford, CA, 3 Department of Electrical Engineering and Computer Science, Stanford, Stanford, CA B1058/P486 An experimentally driven coarse-grained computational model of the axonal cytoskeleton. M. Soheilypour1, M. Peyro1,2, M. Krieg3, R. Fetter3, M.B. Goodman3, M. Mofrad1,2; 1Department of Bioengineering, University of California, Berkeley, Berkeley, CA, 2Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, 3 Department of Molecular and Cellular physiology, Stanford University, Stanford, CA B1059/P487 Distribution patterns of zebrafish neuronal intermediate filaments, inaa and inab. M. Liao1, C. Chien1; 1Anatomy and Cell Biology, National Taiwan University, Taipei, Taiwan

B1066/P494 Environmental complexity and food availability affect the proliferation of neuroblasts in the brain of crickets (Acheta domesticus). G.M. Downing1, C.A. Moffatt1; 1Biology, San Francisco State University, San Francisco, CA B1067/P495 Opposing functions of the F-BAR proteins CIP4 and FBP-17 in neuronal membrane protrusion, tubulovesicle formation and neurite outgrowth. K.L. Taylor1, B. Huynh1, R. Taylor1, K. Richters1, E.W. Dent1; 1Neuroscience, University of Wisconsin Madison, Madison, WI

Establishing and Maintaining Organelle Structure 1 B1069/P496 LEM2 recruits CHMP7 to anaphase chromatin discs in mammalian cells. D. LaJoie*1, M. Gu2, W.I. Sundquist2, A. Frost3, K.S. Ullman1; 1Oncological Sciences, University of Utah, Salt Lake City, UT, 2Biochemistry, University of Utah, Salt Lake City, UT, 3Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1072/P499 Molecular motors and cytoskeleton dynamics control the maturation and secretion of a lysosome-related organelle. L. Ripoll1, X. Heiligenstein1, L. Domingues1, I. Hurbain1,2, M.K. Dennis3,4, M.S. Marks3,4, E. Coudrier5, G. Raposo1,2, C. Delevoye1,2; 1Structure and Membrane Compartments, Institut Curie, PSL Research University, CNRS, UMR144, Paris, France, 2Cell and Tissue Imaging Facility (PICTIBiSA), Institut Curie, PSL Research University, CNRS, UMR144, Paris, France, 3Department of Pathology and Laboratory Medicine, Children Hospital of Philadelphia, Philadelphia, PA, 4Department of Pathology and Laboratory Medicine and Department of Physiology, University of Pennsylvania, Philadelphia, PA, 5Molecular Mechanisms of Intracellular Transport, Institut Curie, PSL Research University, CNRS, UMR144, Paris, France B1073/P500 Role of lysosome alterations in bladder cancer progression. C. De Barros Santos1,2, F. Radvanyi1, B. Goud1,2, K. Schauer1; 1UMR144, Institut Curie, PSL Research University, CNRS, Paris, France, 2 UPMC, Paris, France B1074/P501 Heparin-α-glucosaminide N-acetyltransferase gene inactivation affects the lysosomal integrity of epididymal epithelial cells and the morphology of spermatozoa in adult mice. C.R. Morales1, F.L. Carvelli1, A. Pshezhetsky1, L. Hermo1; 1Anatomy and Cell Biology, McGill University, Montreal, QC B1075/P502 Actin contractility promotes unique Golgi organization in pancreatic beta cells for efficient insulin packaging. X. Zhu1, R. Hu1, G. Gu1, I. Kaverina1; 1Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN B1076/P503 Spatial Proteomic Profiling of the Golgi Apparatus by Indirect Immunofluorescent Microscopy. P. Thul1, R. Pepperkok2, E. Lundberg1; 1Cell Profiling, Science for Life Laboratory (KTH), Stockholm, Sweden, 2Advanced Light Microscopy Facility, European Molecular Biology Laboratory, Heidelberg, Germany

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SUNDAY

B1051/P479 Investigating a novel role for SAX-3/Robo and SLT-1/Slit in mediating axon outgrowth termination in C. elegans. A. Thomas1, D. Coto1, V. Jimenez1, Z. Kieu1, J. Zaroli1, T. Duong1, C. Vargas1, W. Wung1, K. Benedetti1, J. Park1, M. VanHoven1; 1Biological Sciences, San Jose State University, San Jose, CA

Sunday Poster Session

Board No./Presentation No. B1077/P504 MxA-reticulum is a novel organelle distinct from the standard reticulon 4-based endoplasmic reticulum. P.B. Sehgal1, H. Yuan1, F. Liang2, C. Petzold2, K. Dancel-Manning2; 1Cell Biology Anatomy, and Medicine, New York Medical College, Valhalla, NY, 2OCS Microscopy Core, Langone-NYU School of Medicine, New York, NY B1078/P505 The morphology of the endoplasmic reticulum is influenced by cytoplasmic volume in Xenopus laevis. R. Mukherjee1, D.L. Levy1, J.S. Oakey2, K. Nelson2; 1Molecular Biology, University of Wyoming, Laramie, WY, 2Chemical Engineering, University of Wyoming, Laramie, WY B1079/P506 Proximity-specific ribosome profiling reveals efficient co-translational ER targeting in the absence of SRP. E.A. Costa1, J.S. Weissman1; 1Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA B1080/P507 The Cell Atlas: Creation of an image-based atlas of the subcellular distribution of the human proteome. E. Lundberg1, C. AitBlal1, T.L. Alm1, L. Björk1, A. Bäckström1, F. Danielsson1, J. Fall1, M. Hjelmare1, D. Mahdessian1, R. Schutten1, M. Skogs1, C. Stadler1, D.P. Sullivan1, P. Thul1, M. Wiking1, C.F. Winsnes1, L. Åkesson1, M. Uhlén1; 1Proteomics and Nanobiotechnology, Science for Life Laboratory (KTH), Stockholm, Sweden B1081/P508 Profiling the human cytoplasmic proteome. D. Mahdessian1, M. Wiking1, L. Åkesson1, F. Danielsson1, C. AitBlal1, D.P. Sullivan1, P. Thul1, C. Gnann1, A. Bäckström1, J. Fall1, R. Schutten1, L. Björk1, M. Hjelmare1, M. Skogs1, C. Stadler1, M. Uhlén1, E. Lundberg1; 1Science for Life Laboratory, Royal Institute of Technology (KTH), Stockholm, Sweden B1082/P509 Tetraspanins as novel regulators of secretory granule biogenesis. C.J. Ma1,2, J.A. Brill1,2,3; 1Institute of Medical Science, University of Toronto, Toronto, ON, 2Cell Biology Program, The Hospital for Sick Children, Toronto, ON, 3Department of Molecular Genetics, University of Toronto, Toronto, ON B1083/P510 S-nitrosylation of Laforin inhibits its phosphatase activity and is implicated in Lafora disease. A. Satoh1, R. Toyota1, R. Imajo1, Y. Honjo2; 1Biotechnology, Okayama University, Okayama, Japan, 2 2Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan

Sunday Poster Session B1084/P511 Compromised phagosome maturation underlies defective rod outer segment clearance in cultured iPSC-derived RPE cells from SmithLemli-Opitz Syndrome patients. S.J. Fliesler1,2, S. Ramachandra Rao1,2, N. Mas Gomez3, B.A. Pfeffer1,2, A. Rowsam1, C.H. Mitchell3; 1Ophthalmology and Biochemistry, SUNY-University at Buffalo, Buffalo, NY, 2Research Service, VA Western NY Healthcare System, Buffalo, NY, 3Anatomy Cell Biology, University of Pennsylvania, Philadelphia, PA B1085/P512 Depletion of ARMS enhances oxidative stress-mediated autophagy activity primed for differential response in a cell context-dependent way. Y. Liao1, P. Huang2; 1Dermatology, College of Medicine, National Taiwan University, Taipei, Taiwan, 2Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan B1086/P513 Planar mitotic spindle rotation event precedes proneural cell fate selection in the early Drosophila embryo. N.L. Gaytan1, B. Riggs1; 1Biology, San Francisco State University, San Francisco, CA B1087/P514 Acute hyperglycemia alters cell structure of beta-2-tanycytes from the median eminence. F.A. Martinez1, M. Cifuentes2, K. Salazar1, N. Jara1, C. Albarran1, F.J. Nualart1; 1Departmen of cell Biology and and Center for Advanced Microscopy CMA BIOBIO, University of Concepción, Concepción, Chile, 2 Department of Cell Biology, Genetics and Physiology, and CIBER-BBN., University of Málaga, Málaga, Spain B1088/P515 Better than Membranes at the Origin of Life? H.G. Hansma1; 1Physics, University of California, Santa Barbara, CA

Mitochondria, Chloroplasts, and Peroxisomes 1 B1100/P516 COPI dependent vesicular transport controls peroxisome membrane biogenesis. J. Freitag1, J. Lam1, R.W. Schekman1; 1Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA B1101/P517 Structural and Biochemical Basis for Mitochondrial Dynamics by the Protein Miro. K.P. Smith1, P.J. Focia2, Y. Zhang3, J.L. Klosowiak1, D.M. Freymann2, S.E. Rice1; 1Cell Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 2Biochemistry Molecular Genetics, Northwestern University, Feinberg School of Medicine, Chicago, IL, 3Chemistry, Northwestern University, Weinberg College of Arts Sciences, Evanston, IL B1102/P518 Unique functional properties of the Mitofusin proteins. S.C. Hoppins1; 1Biochemistry, University of Washington, Seattle, WA

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B1103/P519 MIEF1/2 functions in coordination with Mff to regulate the balance of mitochondrial dynamics in mammals. R. Yu1, T. Liu1, S. Jin2, C. Ning1, U. Lendahl2, M. Nistér1, J. Zhao1; 1OncologyPathology, Karolinska Institutet, Stockholm, Sweden, 2Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden B1104/P520 Visualization of the inner mitochondrial membrane during mitochondrial division by 4D structured illumination microscopy. C.M. Termini1,2, H. Rakusova1,3, S.C. Lewis1,4, J. Nunnari1,4; 1Marine Biological Laboratory, Woods Hole, MA, 2Pathology, University of New Mexico, Albuquerque, NM, 3McGill University, Quebec, Canada, 4Molecular and Cellular Biology, University of California, Davis, Davis, CA B1105/P521 A conserved membrane bending activity of Mic60 is necessary for cristae formation. D. Tarasenko1, M. Barbot1, D.C. Jans2, B. Kroppen1, G. Heim3, W. Möbius4,5, S. Jakobs2,6, M. Meinecke1,7,8; 1Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany, 2 Department of Neurology, University Medical Center Göttingen, Göttingen, Germany, 3Electron Microscopy Facility, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 4Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany, 5Center Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), Göttingen, Germany, 6Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 7European Neuroscience Institute Göttingen, Göttingen, Germany, 8Göttinger Zentrum für Molekulare Biowissenschaften, Göttingen, Germany B1106/P522 Peroxisomes are essential for germ cell development. A. Brauns1,2; 1Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany, 2Department of Anatomy and Cell Biology, Department of Anatomy and Justus Liebig-University, Gießen, Germany B1107/P523 Purification and isolation of inner mitochondrial membranes from mammalian and Xenopus oocytes for electrophysiological interrogation. L. Gabelev1; 1MCB, UC Berkeley, Berkeley, CA B1108/P524 Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities. H.A. Ping1, L.M. Kraft1, W. Chen1, A. Nilles1, L.L. Lackner1; 1Molecular Biosciences, Northwestern University, Evanston, IL B1109/P525 MIC60 regulates PINK1 activation and Parkin recruitment to damaged mitochondria through the cAMP/PKA signaling pathway. S. Akabane1, M. Uno1, S. Shimazaki1, T. Oka1; 1Life Science, Rikkyo University, Tokyo, Japan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1110/P526 Dose Dependent Effects of Dimethyl Sulfoxide on the Mitochondria of Hepatocellular Carcinoma Cells. R.G. Aktas1, H. Isan1, E.B. Caliskan2, O.E. Tok3, M.S. Aydin3, O.T. Kaya4; 1Cancer and Stem Cell Research Center, School of Medicine, Maltepe University, Istanbul, Turkey, 2School of Medicine, Istanbul University, Istanbul, Turkey, 3Histology Embryology, School of Medicine, Bezm-i Alem Vakif University, Istanbul, Turkey, 4Histology Embryology, School of Medicine, Marmara University, Istanbul, Turkey

B1112/P528 Estrogen receptor alpha 36 is mostly localized in mitochondria in human uterine smooth muscle and leiomyoma cells. Y. Yan1, L. Yu1, L. Castro1, D. Dixon1; 1Molecular Pathogenesis Group, National Toxicology Program Laboratory (NTPL), Division of the NTP (DNTP), National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC B1113/P529 Down-regulation of glucose transport and metabolism by high extracellular glucose concentration in vascular smooth muscle cells. A. Perez1, M. Brenet1, C.X. Bittner2, F. Barros2, C. Villanueva1, C. Gonzalez1, C.B. Gonzalez1; 1Department of Physiology, Universidad Austral de Chile, Valdivia, Chile, 2 Centro de Estudios Cientificos, Valdivia, Chile B1114/P530 Intracellular Calcium Modulates Mitochondrial Shape and Activity in Podocytes. E. Dobrinskikh1, S.I. Al-Juboori2, L. Lewis1, P. Zerfas3, J. Blaine1; 1Department of Medicine, University of Colorado Denver, Aurora, CO, 2Department of Electrical Engineering, University of Colorado Denver, Aurora, CO, 3Electron Core Microscopy Facility, NIH, Bethesda, MD B1115/P531 Mitochondrial damage affects cell growth and cell cycle progression by PINK1/Parkin. D.P. Sideris1, A.M. Pickrell1, N. Giagtzoglou2, C. Wang1, R.J. Youle1; 1NINDS, National Institutes of Health, Bethesda, MD, 2Pathway Discovery, Biogen Inc, Cambridge, MA B1116/P532 Effects of pink1, buffy, deBcl, and presenilin (psn) genes on mitochondrial health in Drosophila melanogaster. W.K. Abdel Qader1, K. Hammock1, K. Duty1, H. Chung1; 1Biology, University of West Florida, Pensacola, FL B1117/P533 Mitochondrial heme distribution: Impact of heterologous heme-binding proteins in mitochondrial sub compartments to probe heme transport. M. Jeong1, D. Winge1; 1Departments of Medicine and Biochemistry, University of Utah Health Sciences Center, Salt Lake City, UT

B1118/P534 Investigating effects of Presenilin on mitochondrial health. K. Hammock1, K. Duty1, W.K. Abdel Qader1, B. Mershon1, A. Sakhichand1, A. Barajas1, A. Ejikemeuwa1, H. Chung1; 1Biology, University of West Florida, Pensacola, FL

Lipids and Membrane Microdomains 1 B1119/P535 TMEM24, a lipid transporter at ER-PM contacts, regulates pulsatile insulin secretion. M. Messa1,2,3,4, J.A. Lees1, E.W. Sun1,2,3,4, H. Wheeler1,2,3,4, F. Torta5, M.R. Wenk5, K.M. Reinisch1, P. De Camilli1,2,3,4,6; 1Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 2Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 3Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT, 4Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 5Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 6Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT B1120/P536 RASSF4 regulates PIP2 and formation of ER-plasma membrane junctions. Y. Chen1, C. Chang1, J. Liou1; 1Physiology, UT Southwestern, Dallas, TX B1121/P537 Control of plasma membrane lipid homeostasis by the extended synaptotagmins. Y. Saheki1,2,3,4,5,6, X. Bian*2,3,4,5,6, C.M. Schauder*3, Y. Sawaki2,3,4,5,6, M.A. Surma7, C. Klose7, F. Pincet8, K.M. Reinisch3, P. De Camilli2,3,4,5,6; 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore, 2Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 3Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 4Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 5Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT, 6Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT, 7Lipotype GmbH, Dresden, Germany, 8Laboratoire de Physique Statistique, Ecole Normale Supérieure de Paris, Université Pierre et Marie Curie, Université Paris Diderot, Centre National de la Recherche Scientifique, Paris, France

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1122/P538 Endosome-ER contacts control actin nucleation and retromer function through VAP-dependent regulation of PI4P. R. Dong1,2,3,4, Y. Saheki1,2,3,4, S. Swarup4, L. Lucast1,2,3,4, J.W. Harper5, P. De Camilli1,2,3,4,6; 1Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 2Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 3Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 4Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT, 5Department of Cell Biology, Harvard Medical School, Boston, MA, 6Kavli Institute for Neurosciences, Yale University School of Medicine, New Haven, CT B1123/P539 Molecular mechanisms of lateral diffusion barriers function in the yeast ER. R. Prasad1, A. Sliwa-Gonzalez1, J. Saarikangas1, Y. Barral1; 1Institute of Biochemistry, ETH Zürich, Zurich, Switzerland B1124/P540 Hallmarks of reversible phase separation in living, unperturbed cell membranes. S. Rayermann1, G.E. Rayermann1, A.J. Merz2, S.L. Keller1; 1Chemistry, University of Washington, Seattle, WA, 2Biochemistry, University of Washington, Seattle, WA B1125/P541 Polyunsaturated fatty acids remodel membranes to potentiate osteogenic differentiation of mesenchymal stem cells. K.R. Levental1, M.A. Surma2, A. Skinkle3, J.H. Lorent1, Y. Zhou1, C. Klose2, J.T. Chang1, J.F. Hancock1, I. Levental1; 1Integrative Biology and Pharmacology, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, 2Lipotype, GmbH, Dresden, Germany, 3Rice University, Houston, TX B1126/P542 Identifying the role of Candida albicans vacuolar ATP binding cassette transporter in cellular homeostasis and virulence. N.K. Khandelwal1, D. Sanglard2, A.K. Mondal1, R. Prasad3; 1School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, 2Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland, 3 Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon, India B1127/P543 The Biophysical and Biochemical Polarization of the Epithelial Plasma Membrane. A. Skinkle1, B. Diaz-Rohrer2, I. Levental2; 1Department of Biosciences, Rice University, Houston, TX, 2Department of Integrative Biology and Pharmacology, McGovern Medical School at the University of Texas Health Science Center, Houston, TX

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B1111/P527 Poldip2 is an oxygen-sensitive mitochondrial protein that controls oxidative/glycolytic metabolism balance. F.I. Paredes Diaz1, K. Sheldon1, G. Torres1, A. San Martin1; 1Cardiology, Emory University, Atlanta, GA

Sunday Poster Session

Board No./Presentation No. B1128/P544 Remodeling of the postsynaptic plasma membrane during neural development. K. Tulodziecka1, B.B. Diaz-Rohrer1, M.M. Farley2, R.B. Chan3, G. Di Paolo3, K.R. Levental1, N.M. Waxham2, I. Levental1; 1Department of Integrative Biology Pharmacology, McGovern Medical at the University of Texas Health Science Center, Houston, TX, 2Department of Neurobiology Anatomy, McGovern Medical at the University of Texas Health Science Center, Houston, TX, 3Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY B1129/P545 Antidepressant action in neural plasma membranes. Y. Liu1, U. Perez-Salas1,2, M.M. Rasenick3, S.L. Veatch4; 1Department of Physics, University of Illinois at Chicago, Chicago, IL, 2 Argonne National Laboratory, Argonne, IL, 3 Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL, 4Department of Biophysics, University of Michigan, Ann Arbor, MI B1130/P546 Perturbation of complex sphingolipid synthesis increases drug resistance in S. cerevisiae. P.K. Hanson1, H.N. Daniel1; 1Biology Department, Birmingham-Southern College, Birmingham, AL B1131/P547 A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans. S. Li1, S.O. Zhang1; 1School of Life Sciences, Capital Normal University, Beijing, China B1132/P548 Lipid droplets are central organelles for meiosis II progression during yeast sporulation. T. Hsu1, R. Chen1, Y. Cheng2, C. Wang2; 1Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, Taiwan, 2Institute of Plant and Microbial Biology, Academia Sinica, Nankang, Taipei, Taiwan B1133/P549 Water-soluble polysaccharides obtained from barley alleviates obesity and dyslipidemia in high-fat diet fed mice. E. Lee1, S. Jeong1, H. Hong2, C. Cho2; 1Traditional Alcoholic Beverage Research Team, Korea Food Research Institute, Seongnam-si, Korea, South, 2 Traditional Food Research Center, Korea Food Research Institute, Seongnam-si, Gyeonggi-do, Korea, South B1134/P550 Role of membrane contact sites in formation of lipid domains during stress. A. Toulmay1, A. Murley2, R. Sarsam2, J. Yamada2, J. Nunnari2, W. Prinz1; 1LCMB, NIDDK, NIH, Bethesda, MD, 2Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA B1135/P551 Dissecting the roles of PLA2-mediated tubules and STARD4 in intracellular cholesterol transport. A.L. Munlyn1, A.Y. Tarren1, H. Beaman1, E.B. Cluett1; 1Biology, Ithaca College, Ithaca, NY

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Sunday Poster Session B1136/P552 Methylglyoxal levels increased in hypercholesterolemic rabbits. L. Simon1, P. Chantarasinlapin2, A. Funes1, T. Saez1, M. Veisaga3, M.A. Barbieri3,4,5, M.W. Fornes1; 1Laboratorio de Investigaciones Andrológicas de Mendoza, Universidad Nacional de Cuyo, Mendoza, Argentina, 2 Department of Dietetics and Nutrition, Florida International University, Miami, FL, 3 Biomolecular Sciences Institute, Florida International University, Miami, FL, 4Fairchild Tropical Botanic Garden, Fairchild Tropical Botanic Garden, Miami, FL, 5Department of Biological Sciences, Florida International University, Miami, FL B1137/P553 GSK3-family Kinases regulate Lipin 1 nuclear localization and lipid homeostasis. L.J. Chan1, J. McQueen1,2, T.R. Peterson3, T.K. Poon1, M. Briggs1, C.D. Roskelley1, V. Measday2, D.M. Sabatini3, C.J. Loewen1; 1Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, 2Wine Research Centre, University of British Columbia, Vancouver, BC, 3Biology, Whitehead Institute for Biomedical Research, Cambridge, MA B1138/P554 Polarized release of T-cellreceptor-enriched microvesicles at the immunological synapse. K. Choudhuri1; 1Microbiology Immunology, University of Michigan Medical School, Ann Arbor, MI B1139/P555 Depletion of plasma membrane PI(4,5)P2 promotes store-operated calcium entry. J.B. Jensen1, E.J. Dickson2, B. Hille1; 1Physiology and Biophysics, University of Washington, Seattle, WA, 2 Physiology and Membrane Biology, University of California, Davis, CA

Signaling from the PM/ Cytoplasm to the Nucleus B1140/P556 The phenotypic conversion of VSMCs is mediated by prostaglandin D2 via ERK signaling pathway. H. Lee1, J. Ha1, Y. Kim1, S. Jin1, F. Vafaeinik1, J. Jang1, S. Bae1; 1Pharmacology, Pusan National University School of Medicine, Yangsan-si, Korea B1141/P557 Actomyosin contractility modulates Wnt signaling through adherens junction stability. E.T. Hall1, E. Hoesing1, E.M. Verheyen1; 1Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC

B1142/P558 Chromatin modifies the decoding of NF-κB signals to regulate transcription. V.C. Wong1, A.K. Chavali2, R.E. Lee3, W. Mothes4, S. Gaudet5,6, K. Miller-Jensen1,2; 1Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, 2Department of Biomedical Engineering, Yale University, New Haven, CT, 3Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, 4 Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, 5Department of Cancer Biology and Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA, 6 Department of Genetics, Harvard Medical School, Boston, MA B1143/P559 Comparative forward genetic screens in haploid human cells reveal new regulatory mechanisms in WNT signaling. A.M. Lebensohn1, R. Dubey1, L.R. Neitzel2, O. Tacchelly-Benites3, E. Yang3, C.D. Marceau4, E.M. Davis5, B.B. Patel1, Z.B. Nejad1, Y. Ahmed3, E. Lee2, J.E. Carette4, R. Rohatgi1; 1Departments of Biochemistry and Medicine, Stanford University School of Medicine, Stanford, CA, 2Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN, 3Department of Genetics and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 4 Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, 5Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO B1144/P560 The transcription factor Fra-1 acts as a linear integrator of ERK activity amplitude and duration. T.E. Gillies1, M. Pargett1, B. Sparta1, M. Minguet Sànchez1, J. Albeck1; 1MCB, University of California Davis, Davis, CA B1145/P561 Identifying the biological roles of a short variant of Large Tumor Suppressor Kinase 1 (Lats1) in growth control. Y. Matsui1, Y. Zhang1, E.M. Lesko2, Z. Lai1,2; 1Biology, The Pennsylvania State University, University Park, PA, 2 Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA B1146/P562 Expression of Wnts in pancreatic islet cells of prediabetic and normal mice. C.B. CollaresBuzato1, D.A. Maschio1, H.C. BarbosaSampaio2; 1Department of Biochemistry and Tissue Biology, University of Campinas, Campinas, Brazil, 2Department of Structural and Functional Biology, University of Campinas, Campinas, Brazil B1147/P563 Nox2 contributes to RANKLinduced osteoclast differentiation by upregulating NFATc1 expression. I. Kang1, C. Kim1; 1pharmacology, Inha University, Incheon, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Sunday Poster Session B1157/P573 Netrin-3 Peptide (C-19) is a Chemorepellent and a Growth Inhibitor in Tetrahymena thermophila. M.S. Merical1, K.W. Ward1, L.G. Parks1, H.G. Kuruvilla1; 1Science and Mathematics, Cedarville University, Cedarville, OH

B1149/P565 Effects of Osthole and Klotho on Advanced Glycation End Products-Induced Hypertrophic Growth in Human Renal Tubular Cells. J. Huang1; 1Biomedicine and Healthcare, Chung Hwa University of Medical Technology, Tainan, Taiwan

B1158/P574 Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver. N. Zhao1, J. Maxson1, R. Zhang1, M. Wahedi1, C.A. Enns1, A. Zhang1; 1Cell, Developmental & Cancer Biology, Oregon Health Science University, Portland, OR

B1150/P566 Regulation of p53 and NF-kB by DGKzeta. T. Tanaka1, K. Goto1; 1Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata, Japan

B1159/P575 A pyrrole-based microtubuledepolymerizing compound reduces pro-inflammatory signaling in RAW264.7 macrophages. S.P. Gilmore1, S. Espinosa de Los Reyes1, K. Fischer-Stenger1, A. Gonye1, O.A. Quintero1, J.T. Gupton2, E. Lis1; 1Biology, University of Richmond, University of Richmond, VA, 2Chemistry, University of Richmond, University of Richmond, VA

B1151/P567 TI-1-162, a hydroxy indenone derivative inhibiting NF-κB, ameliorates colitis by suppression of TNF-α expression. P. Gurung1, S. Banskota1, E. Lee1, Y. Lee1, M. Park1, J. Kim1; 1College of Pharmacy, Yeungnam University, Gyeongsan, Korea, South B1152/P568 The necessity of TRPM2mediated Ca2+ signals in the exerciseinduced expression of slow muscle fibers. S. Lee1, B. Kim1, D. Park1, U. Kim1; 1Department of Biochemistry, National Creative Research Laboratory for Ca2+ Signaling Network, Chonbuk National University Medical School, Jeonju, Korea B1153/P569 Semaphorin Receptor Function in Hedgehog Signal Transduction. J.M. Pinskey1, R.J. Giger1, B.L. Allen1; 1Cell and Developmental Biology, University of Michigan, Ann Arbor, MI B1154/P570 Anti-inflammatory effects of an improved pyrrole-based microtubuledepolymerizing compound on RAW264.7 macrophages. E.C. Li1, A. Gonye1, S.P. Gilmore1, J.T. Gupton2, K. FischerStenger1; 1Department of Biology, University of Richmond, Richmond, VA, 2Department of Chemistry, University of Richmond, Richmond, VA B1155/P571 Investigating the role of angiomotin in directing mechanosensitive neural stem cell differentiation. P.H. Kang1, M. Kang1, D. Schaffer1,2,3, S. Kumar1,3,4; 1Bioengineering, University of California, Berkeley, Berkeley, CA, 2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, 3Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA, 4Physical Biosciences, Lawrence Berkeley National Laboratory, Berkeley, CA

B1160/P576 Regulation of Interferon Signaling by a Calcium-induced miRNA in Primary Human Salivary Gland Epithelial Cells. S. Jang1, M. Tandon1, P. Perez Riveros1, C. Zheng1, I. Alevizos1; 1NIDCR, NIH, Bethesda, MD B1161/P577 Localized confocal image analyses reveal a rate-limiting step of ERK signal transduction processes. K. Mouri1, Y. Okada1,2; 1QBiC, RIKEN, Osaka, Japan, 2Department of Physics, Graduate School of Science, University of Tokyo, Tokyo, Japan B1162/P578 Cav1 orchestrates glucocorticoid-mediated inhibition of keratinocyte migration and cutaneous wound healing. I. Jozic1, L. Liang1, A.P. Sawaya2, G.D. Glinos1, I. Pastar1, M. Tomic-Canic1,2,3; 1Wound Healing and Regenerative Medicine Research Program, Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 2Cellular and Molecular Pharmacology Graduate Program in Biomedical Sciences, University of Miami Miller School of Medicine, Miami, FL, 3John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL B1163/P579 Digestion of apoptotic adipocytes by macrophages occurs via lysosomal exocytosis and is mediated by TLR2 and MyD88. V.C. Barbosa-Lorenzi1, A.S. Haka1, F.R. Maxfield1; 1Biochemistry, Weill Cornell Medical College, New York, NY

B1156/P572 Human cytomegalovirus actively modulates the aryl hydrocarbon receptor-signaling pathway to enhance the production of progeny virus. P. Naseri Nosar1, J. Hwang1, T.E. Shenk1; 1Department of Molecular Biology, Princeton University, Princeton, NJ

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1164/P580 The unfolded protein response (UPR) provides gain amplification to brain-derived neurotrophic factor (BDNF) signaling in cortical mouse neurons. P. Mardones1,2, R. Vidal1,2,3,4, G. Martinez1,2,3, C. Hetz1,2,3,4,5,6; 1Biomedical Neuroscience Institute, University of Chile, Santiago, Chile, 2 Institute of Biomedical Sciences, University of Chile, Santiago, Chile, 3Center for Geroscience, Brain Health and Metabolism, Santiago, Chile, 4Neurounion Biomedical Foundation, Santiago, Chile, 5Buck Institute for Research on Aging, Novato, CA, 6 Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA B1165/P581 Gamma Secretase Activity is Necessary for Bone Morphogenetic Protein-7-Induced Dendritic Growth in Embryonic Rat Sympathetic Neurons. K. Karunungan1, S. Thapa1, P.J. Lein2, V. Chandrasekaran1; 1Biology, Saint Mary’s College of CA, Moraga, CA, 2Molecular Biosciences, University of California at Davis, Davis, CA

Signaling Scaffolds and Microdomains B1200/P582 Proteomic analysis of GRB2 signaling networks in HER2-positive breast cancer. A. Beigbeder1,2,3, F. Chartier1,3, N. Bisson1,2,3,4; 1Division of Oncology, Centre de Recherche du CHU de Québec, Québec, QC, 2Cancer Research Centre, Université Laval, Québec, QC, 3 Québec Network for Research on Protein Function, Engineering, and Applications (PROTEO), Université Laval, Québec, QC, 4 Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec, QC B1201/P583 Endosomal reactive oxygen species act as signaling mediators for the activation of Akt/PKB signaling pathway. S. Park1, D. Kang1; 1Life Science, Ewha Womans University, Seoul, Korea, South B1202/P584 Identification of nonoverlapping functions between adaptor proteins NCK1 and NCK2. K. Jacquet1,2,3, U. Dionne1,2,3, N. Bisson1,2,3,4; 1Cancer Research Center, Quebec city, QC, 2 PROTEO, Quebec city, QC, 3Oncology Department, CHU de Quebec Research Center, Quebec city, QC, 4Molecular Biology, Medical Biochemistry, and Pathology, Laval University, Cancer Research Center, Quebec city, QC B1203/P585 The scaffold protein RACK1 regulates preformed mediator release in mast cells and affects F-actin dynamics. E.G. Freitas Filho1, C. Oliver1, M.C. Jamur1; 1Cell and Molecular Biology and Pathogenic Bioagents, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil

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SUNDAY

B1148/P564 Carbon monoxide enhances the differentiation and polarization of murine macrophages. R. Kim1, I. Kang1, Y. Kwon1, C. Kim1; 1Pharmacology, Inha University School of Medicine, Incheon, Korea

Board No./Presentation No. B1204/P587 The Tetraspanin CD82 Regulates Hematopoietic Stem Cell Interactions with the Bone Marrow Microenvironment. C.A. Saito Reis1, K.D. Marjon1, E.M. Pascetti1, K.L. Karlen1, R.J. Dodd1, C.M. Termini1, J.M. Gillette1; 1Pathology, University of New Mexico Health Science Center, Albuquerque, NM B1205/P586 CD82 Membrane Organization Regulates the Spatiotemporal Dynamics of PKCα Signaling. C.M. Termini1, K.A. Lidke2, J.M. Gillette1; 1Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM, 2Physics and Astronomy, University of New Mexico, Albuquerque, NM B1206/P588 Size-dependent protein segregation triggers macrophage phagocytosis. M.H. Bakalar1, A.M. Joffe1, M. Podolski1, E.M. Schmid1, D.A. Fletcher1; 1Department of Bioengineering & Biophysics Program, University of California, Berkeley, Berkeley, CA B1207/P589 Correlation of Cyclic AMP levels with the Expression of AKAP150 and Calcineurin in MitogenStimulated Immortalized Rat Schwann Cell Culture. M. Blazaskie1, A. Rehrig1, G. Emmett2, A. Nale2, J. Stephens2, A.L. Asirvatham1; 1Biology, Misericordia University, Dallas, PA, 2Physics, Misericordia University, Dallas, PA B1208/P590 Differential Expression of AKAP95, Krox-20 and Cyclin D3 in Mitogen-stimulated Immortalized Rat Schwann Cell Culture. A. Rehrig1, M. Blazaskie1, A.L. Asirvatham1; 1Biology, Misericordia University, Dallas, PA B1209/P591 Regulation of the nuclear PKA holoenzyme. T. Clister1,2, V. Sample2, J. Zhang1,2; 1Pharmacology, University of California, San Diego, La Jolla, CA, 2 Pharmacology, Johns Hopkins University, Baltimore, MD B1210/P592 PLK1 spatial synchronization and activity during mitosis. E.G. Colicino1, H. Hehnly1; 1Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, NY B1211/P593 Ligand-induced growth and compaction of CD36 nanoclusters induce Fyn signaling. J.M. Githaka1, A.R. Vega2, M.A. Baird3, M.W. Davidson3, K. Jaqaman2, N. Touret1; 1Biochemistry, University of Alberta, Edmonton, AB, 2Biophysics, UT Southwestern Medical Center, Dallas, TX, 3 National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL B1212/P594 Fission yeast Cdr2 nodes promote growth-dependent inactivation of the cell cycle regulator Wee1. C. Allard1, J.B. Moseley1; 1Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH

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Sunday Poster Session B1213/P595 A Diffusion Trap at the Caulobacter Cell Poles Leads to Spatially Resolved Transcription. K. Lasker1, A. von Diezmann2, D.G. Ahrens1, T.H. Mann1, W.E. Moerner2, L. Shapiro1; 1Developmental Biology, Stanford University, Stanford, CA, 2 Chemistry, Stanford University, Stanford, CA B1214/P596 In Vitro Reconstitution of T Cell Receptor–Mediated Segregation of the CD45 Phosphatase. C.B. Carbone1,2, N. Kern1,2, R. Fernandes2,3, K.C. Garcia2,3, R.D. Vale1,2; 1Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 2Howard Hughes Medical Institute, San Francisco, CA, 3Molecular Physiology, Stanford University, Stanford, CA B1215/P597 The role of VEGF and molecular scaffolds in the mobility of VEGFR-2 on the endothelial cell surface. B. Da Rocha-Azevedo1, S. Lee1, M. Kittisopikul1, T. Kim1, K. Jaqaman1; 1Biophysics, UT Southwestern Medical Center, Dallas, TX B1216/P598 Activation time distribution of membrane recruitment process revealed by first-passage analysis of full-length SOS. W. Huang1, S. Alveraz1, Y. Lee1, Y. Kondo2, J.K. Chung1, H. Lam1, J. Kuriyan1,2, J.T. Groves1; 1Department of Chemistry, University of California, Berkeley, Berkeley, CA, 2Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA

Mechanotransduction 1 B1218/P599 Activating the nuclear piston mechanism to generate intracellular pressure during tumor cell 3D migration. R.J. Petrie1, H.M. Harlin1, K.M. Yamada2; 1Biology, Drexel University, Philadelphia, PA, 2National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD B1219/P600 As the beating heart stiffens in development, so does the nuclear lamina. S. Cho1, S. Majkut1,2, A. Abbas1, K. Vogel1, M. Tewari1, J. Irianto1, C. Chen3, B.L. Prosser3, D.E. Discher1; 1Molecular Cell Biophysics Laboratory, University of Pennsylvania, Philadelphia, PA, 2 Department of Physics Astronomy, University of Pennsylvania, Philadelphia, PA, 3Department of Physiology, Penn Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

B1220/P601 New insight into the interplay of actomyosin contractility and LINC complex in regulation of nuclear shape and high-speed tumor cell motility using precisely sized collagen I/fibronectin1D nanofibers. V.P. Sharma1,2, J. Williams3, E. Leung2, J. Sanders3, R.J. Eddy2, J. Castracane3, J.S. Condeelis1,2; 1Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY, 2Anatomry and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, 3Colleges of Nanoscale Science and Engineering, SUNY Polytechnic Institute, Albany, NY B1221/P602 Molecular insights into LINC complex proteins SUN1 and SUN2. Z. Jahed1, D. Fadavi1, G. Luxton2, M. Mofrad1; 1Bioengineering, University of California, Berkeley, CA, 2College of Biological Sciences, University of Minnesota, Minneapolis, MN B1222/P603 Mechanical response of nesprin-2G to cytoskeletal forces regulates LINC complex-dependent mechanotransdution. H. Shams1, M. Mofrad1, G. Luxton2; 1Bioengineering, University of California, Berkeley, Berkeley, CA, 2College of Biological Sciences, University of Minnesota, Saint Paul, MN B1223/P604 Optogenetic Control of Traction Forces, Cell-Cell Forces and Mechanotransduction. L. Valon1, A. MarínLlauradó1, T.P. Wyatt2,3, G. Charras3,4, X. Trepat1,5,6; 1Institute for Bioengineering of Catalonia, Barcelona, Spain, 2Laboratory for Molecular Cell Biology, University College London, London, United Kingdom, 3London Centre for Nanotechnology, London, United Kingdom, 4Department of Cell and Developmental Biology and Institute for the Physics of Living Systems, University College London, London, United Kingdom, 5 University of Barcelona, Barcelona, Spain, 6 ICREA, Barcelona, Spain B1224/P605 Multiparametric analysis of cell morphology shows that beta-PIX, Cdc42, Rac1, and PAK2 drive YAP activation in breast epithelial cells. J.E. Sero1, C. Bakal1; 1Cancer Biology, Institute of Cancer Research, London, United Kingdom B1225/P606 YAP-independent mechanotransduction of mammary epithelial cells in 3D culture model of cancer invasion. J.Y. Lee1, J. Chang2, S. Nam1, O. Chaudhuri1; 1Mechanical Engineering, Stanford University, Stanford, CA, 2Genetics, Stanford University, Stanford, CA B1226/P607 Substratum stiffness and Wnt3a synergistically regulate cell proliferation via YAP/TAZ. S. Han1, C.M. Nelson1,2; 1Molecular Biology, Princeton University, Princeton, NJ, 2Chemical and Biological Engineering, Princeton University, Princeton, NJ

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1227/P608 Matrix Mechanics Controls FHL2 Movement to the Nucleus to Activate p21/CDKN1A Expression. N. Nakazawa1, A.R. Sathe1, G. Shivashankar1,2,3, M.P. Sheetz1,3,4; 1Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 2FIRC Institute of Molecular Oncology, Milan, Italy, 3Biological Science, National University of Singapore, Singapore, Singapore, 4Biological Science, Columbia University, New York, NY

B1229/P610 Interplay between Rho-GEF Solo and keratin filaments is crucial for mechanotransduction in epithelial cells. S. Fujiwara1,2, H. Abiko2, K. Ohashi2, K. Mizuno2; 1Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Osaka, Japan, 2Department of BioMolecular Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan B1230/P611 Spatial Regulation of RhoA Reveals Zyxin-mediated Elasticity of Stress Fibers. P.W. Oakes1,2, E. Wagner3, C.A. Brand4, D. Probst4, M. Linke4, U.S. Schwarz4, M. Glotzer3, M.L. Gardel2; 1Department of Physics, University of Rochester, Rochester, NY, 2Institute for Biophysical Dynamics, James Franck Institute and Department of Physics, University of Chicago, Chicago, IL, 3Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 4Institute for Theoretical Physics and BioQuant, Heidelberg University, Heidelberg, Germany B1231/P612 Identifying the activator of PLC-1 in Caenorhabditis elegans ovulation. A.D. Cecchetelli1, C.G. Clifford1, E.J. Cram1; 1Biology, Northeastern University, Boston, MA

B1234/P615 Distinct subcellular signaling pathways between Pyk2, Src, and FAK by mechanical force and inflammatory cytokines. Q. Wan1, H. Yokota1,2, S. Na1,2; 1Biomedical Engineering, Purdue University, West Lafayette, IN, 2Biomedical Engineering, Indiana University-Purdue University Indianapolis, Indianapolis, IN B1235/P616 Biomechanical forces modulate epithelial competence and regeneration patterning during woundinduced hair neogenesis. H. Harn1,2,3, P. Chiu2, C. Lin2, H. Chen4, C. Wu2,5, M. Tang2,3, C. Chuong1,2, M.W. Hughes2; 1Department of Pathology, University of Southern California, Los Angeles, CA, 2International Laboratory of Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan, 3Department of Physiology, National Cheng Kung University, Tainan, Taiwan, 4 Department of Mechanical Engineering, National Chung Hsing University, Taichung, Taiwan, 5Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan B1236/P617 Membrane tension acts through PLD2 and mTORC2 to limit actin network assembly during neutrophil migration. A. Diz-Muñoz1,2,3, K. Thurley4, S. Chintamen3, S.J. Altschuler4, L.F. Wu4, D.A. Fletcher1, O.D. Weiner3; 1Bioengineering, UC Berkeley, Berkeley, CA, 2CBB, EMBL, Heidelberg, Germany, 3CVRI, UCSF, San Francisco, CA, 4Pharmaceutical Chemistry, UCSF, San Francisco, CA B1237/P618 Functional and genetic dissection of mechanosensory organs of Drosophila. C. Guan1,2, N. Scholz3, M. Nieberler1, M.C. Göpfert4, C.F. Schmidt2, R.J. Kittel1, T. Langenhan3; 1Neurophysiology, Institute of Physiology, Würzburg, Germany, 2Biophysics, Third Institute of Physics, Göttingen, Germany, 3Department of General Biochemistry, Institute of Biochemistry, Leipzig, Germany, 4Cellular Neurobiology, Schwann-Schleiden Research Centre, Göttingen, Germany

B1232/P613 Contact Guidance requires spatial control of leading edge protrusion. G.R. Ramirez-SanJuan1,2,3,4, P.W. Oakes1,3,4,5, M.L. Gardel1,3,4; 1Physics, University of Chicago, Chicago, IL, 2 Graduate Program in Biophysical Sciences, University of Chicago, Chicago, IL, 3Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, 4James Frank Institute, University of Chicago, Chicago, IL, 5Physics, University of Rochester, Rochester, NY

B1238/P619 Control of JAK/STAT signaling by caveolae mechanotransduction. N. Tardif1, C. Blouin1, R. Ruez1, C. Viaris de Lesegno1, C. Lamaze1; 1CNRS UMR 3666 Inserm U1143 Team membrane dynamics and mechanics of intracellular signaling, Institut Curie, PSL research university, Paris, France

B1233/P614 High hydrostatic pressure induces cytoskeletal organization and signal transduction. M. Morimatsu1, A. Fujita1, K. Takahashi1, K. Naruse1; 1Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

B1240/P621 Identification and characterization of the sole Drosophila alpha-tubulin acetylase dTAT. C. Yan1, F. Weng2, Y. Peng1, K. Luedke1, C. Williams1, G. de la Rosa1, B. Jenkins3, J. Wildonger3, Y. Xiang2, S. Rogers4, J.Z. Parrish1; 1Biology, University of Washington, Seattle, WA, 2Neurobiology, University of Massachusetts Medical School, Worcester, MA, 3Biochemistry, University of Wisconsin, Madison, WI, 4Biology, University of North Carolina, Chapel Hill, NC

B1239/P620 Calcium sparks controlling cell mechanosensing. A.Y. Moalim1, S.V. Plotnikov1; 1Department of Cell and Systems Biology, University of Toronto, Toronto, ON

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1241/P622 Investigating the morphology and cytoskeletal organization of zebrafish keratocytes in vivo. A.S. Kennard1, J.A. Theriot1,2,3; 1Biophysics Program, Stanford University, Stanford, CA, 2 Biochemistry, Stanford University, Stanford, CA, 3Howard Hughes Medical Institute, Stanford University, Stanford, CA

Intermediate Filaments B1242/P623 Drafting the intermediate filament proteome. M. Wiking1, C. AitBlal1, L. Björk1, A. Bäckström1, F. Danielsson1, J. Fall1, C. Gnann1, M. Hjelmare1, D. Mahdessian1, R. Schutten1, M. Skogs1, C. Stadler1, D.P. Sullivan1, P. Thul1, C.F. Winsnes1, L. Åkesson1, M. Uhlén1, E. Lundberg1; 1Affinity Proteomics, Science for Life Laboratories (KTH), Solna, Sweden B1243/P624 Absence of the Intermediate Filament Synemin Causes Abnormalities in Cardiac and Skeletal Muscle. K.P. Garcia-Pelagio1,2, L. Chen2, R.J. Bloch2; 1Physics Department, School of Sciences, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, 2Physiology Department, School of Medicine, University of Maryland, Baltimore, MD B1244/P625 Head domains of intermediate filament proteins form cross-β polymers and interact with the low-complexity domain of the Fused in Sarcoma (FUS) RNA binding protein. E. Mori1, Y. Lin1, M. Kato1, S. Xiang1, L. Wu1, I. Kwon2, S.L. McKnight1; 1Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX, 2Department of Anatomy and Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South B1245/P626 Filaments formed by the translation initiation factor eIF2B: high-resolution insights into a survival strategy. G. Marini1, E. Nüske1, S. Alberti1, G. Pigino1; 1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B1246/P627 Intermediate filaments EXC-2/IFC-2 and IFA-4 Maintain Tube Structure of the Excretory Canal of the Nematode C. elegans. H. Al Hashimi1, M. Buechner1; 1Molecular Biosciences, University of Kansas, Lawrence, KS B1247/P628 Vimentin regulates Notch signaling during angiogenesis. D. Antfolk1,2, M. Sjöqvist1,2, F. Cheng1,2, K. Isoniemi1,2, C. Duran3, A. Rivero-Muller1,2, C. Antila1,2, R. Niemi1,2, S. Landor1,2, C. Bouten4, K.J. Bayless3, J.E. Eriksson1,2, C. Sahlgren1,2,4; 1Turku Centre for Biotechnology, Turku, Finland, 2Department of Biosciences, Abo Akademi University, Turku, Finland, 33Department of Molecular Cellular Medicine, Texas AM University Health Science Center, College Station, TX, 4 Department of Biomedical Engineering, Technical University of Eindhoven, Eindhoven, Netherlands

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B1228/P609 Stretch-dependent Akt activation and nuclear localization in epithelial cells. M.L. Ewald1, D.J. Renner1, S. Yamada1; 1Biomedical Engineering, University of California, Davis, Davis, CA

Sunday Poster Session

Board No./Presentation No.

Cell-Cell Junctions 1 B1249/P629 Activation of Adenosine Receptors in Endothelial Cells Increases Connexin 43 Gap Junction Plaques: Analysis of Dynamic Changes in Connexin 43 Synthesis and Localisation. A. Bader1, A. Klett1, K. Schmitt1, A. Ngezahayo1,2; 1Institute of Biophysics, Leibniz University Hannover, Hannover, Germany, 2Center for Systems Neuroscience, University of Veterinary Medicine Hannover, Hannover, Germany B1250/P630 The dileucine motifs in the carboxy tail of connexin32 control its assembly into gap junctions. A. Ray1, P. Katoch1, N. Jain1, P.P. Mehta1; 1Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE B1251/P631 Connexin 43 regulates cell cycle and invasion in non-neoplastic breast epithelium. S.F. Fostok1, D.B. Bazzoun1,2, F.A. Yassine1, S.A. Lelievre2,3, R.S. Talhouk1; 1Department of Biology, American University of Beirut, Beirut, Lebanon, 2Department of Basic Medical Sciences, Purdue University, West Lafayette, IN, 3Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN B1252/P632 Development of a Biological Assay for Assessing aCT-1 Function. K. Hancock1,2, R. Gourdie2, J. Jourdan2; 1School of Medicine, Virginia Tech Carilion, Roanoke, VA, 2Research Institute, Virginia Tech Carilion, Roanoke, VA B1253/P633 Analysis of the oligomerization behavior of concatemeric connexins. P. Schadzek1, D. Hermes1, A. Ngezahayo1,2; 1Institute of Biophysics, Leibniz University Hannover, Hannover, Germany, 2Center for System Neurosciences (ZSN), Hannover, Germany B1254/P634 Dynamic imaging and visualization of connexin/cytoplasmic organelle interactions. C.L. Bell1, M.A. Stuckey1, M.E. Bisher1, S.A. Murray1; 1Cell Biology, University of Pittsburgh, Pittsburgh, PA B1255/P635 Flares of active RhoA locally reinforce tight junctions. R.E. Stephenson1, T. Higashi1, B. Coy1, T.R. Arnold1, A.L. Miller1; 1Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI B1256/P636 Luminal content of small intestine from prediabetic mice induces epithelial barrier disruption in Caco-2 monolayers in vitro. C.B. CollaresBuzato1, R.B. Oliveira1, V.A. Matheus1, L.P. Canuto1; 1Department of Biochemistry and Tissue Biology, University of Campinas, Campinas, Brazil

Sunday Poster Session B1257/P637 Structural Dynamics of Tight Junctions Modulate the Epithelial Barrier Properties. A. Tervonen1, T. Ihalainen2, D. García León3, S. Nymark1, J. Hyttinen1; 1Electronics and Communications Engineering and BioMediTech, Tampere University of Technology, Tampere, Finland, 2 BioMediTech, University of Tampere, Tampere, Finland, 3Advanced Development in Arrhythmia Mechanisms and Therapy Group, Spanish Cardiovascular Research Center Foundation, Madrid, Spain B1258/P638 Scribble is required for tricellular junction complex formation in Drosophila. Z. Sharifkhodaei1, M. Gilbert1, V.J. Auld1; 1Zoology, University of British Columbia, Vancouver, BC B1259/P639 EpCAM cleavage by matriptase regulates intestinal epithelial function. C. Wu1, X. Feng1, M.C. Udey1; 1Dermatology Branch, National Cancer Institute, Bethesda, MD B1260/P640 The recruitment and function of Anillin at cell-cell junctions. K.M. Dinshaw1, T.R. Arnold1, C.C. Reyes1, A.L. Miller1; 1Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI B1261/P641 Regulation of epithelial barrier function by a TJ-associated actin-binding protein. S. Konishi1,2, M. Uji2, T. Mizuno2, K. Tateishi2, H. Kanoh2, T. Yano2, A. Tamura2, S. Tsukita2; 1Respirat, Med, Grad, Sch, of Med, Kyoto Univ., Kyoto city, Japan, 2Lab, of Biol, Sci,, Grad, Sch, of Frontier, Biosci, and Grad, Sch, of Med, Osaka Univ., Osaka City, Japan B1262/P642 Overexpression of AQP5 in epithelial cells decreases intercellular adhesion. F.H. Login1, H.H. Jensen2, J.J. Morgen1, G.A. Pedersen1, J.S. Koffman2,3, J. Palmfeldt1, P. Bross1, M. Parsons4, L.N. Nejsum1,3; 1Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, 2Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark, 3Interdisciplinary Nanoscience Center, Aarhus University, Aarhus, Denmark, 4 King’s College, London, United Kingdom B1263/P643 TJ-MAP4 up-regulate MLCphosphorylation by binding to MLC, ZO1 and tubulin at tight junction. H. Kanoh1,2, T. Yano2, M. Uji2, A. Tamura2, S. Tsukita2; 1Graduate School of Biostudies, Kyoto university, Kyoto, Japan, 2Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka university, Osaka, Japan B1264/P644 Identifying Novel Components of the Desmosome Proteome Essential for Maintaining Epidermal Integrity. K.A. Badu-Nkansah1; 1Deptartment of Cell Biology, Duke University School of Medicine, Durham, NC B1265/P645 Loss of Desmoplakin controls p38 MAPK-regulated breast and skin cancer cell migration. E.I. Williams1, A.D. Dubash1; 1Biology, Furman University, Greenville, SC

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Integrins and Cell-ECM Interactions B1266/P646 Actin retrograde flow actively aligns and orients ligandengaged integrins in focal adhesions. V. Swaminathan1, J.K. Mathew2, S. Mehta3, P. Nordenfelt4, T.I. Moore5, K. Nobuyasu6, D. Baker6, R. Oldenbourg3, T. Tani3, S. Mayor2, T.A. Springer5, C.M. Waterman1; 1Cell Biology and Physiology Center, NHLBI/ NIH, Bethesda, MD, 2National Center for Biological Sciences, Bangalore, India, 3 Marine Biological Sciences, Woods Hole, MA, 4Division of Infection Medicine, Lund University, Lund, MD, 5Program in Cellular and Molecular Medicine, Harvard University, Boston, MA, 6Department of Biochemistry, University of Washington, Seattle, WA B1267/P647 Nanoscale architecture of the unique focal adhesions and actin cytoskeleton of human pluripotent stem cells. C. Guzman1, A. Stubb1, J. Ivaska1; 1Turku Centre for Biotechnology, University of Turku, Turku, Finland B1268/P648 Molecular Architecture of Adhesions Reflects Cellular Invasion Potential. C.G. Galbraith1, L. Voss1,2, I.M. Gal1, W.N. Voss1, J.A. Galbraith1; 1OCSSB/ BME, OHSU, Portland, OR, 2Biochemistry/ Molecular Biology, Lewis Clark University, Portland, OR B1269/P649 Talin autoinhibition is important for regulating integrin-based cell-ECM adhesion in vivo. A.M. Haage1, K.E. Goodwin1, A. Messenberg1, A.B. Bogutz2, L. Lefebvre2, G. Tanentzapf1; 1Cell Physiological Sciences, University of British Columbia, Vancouver, BC, 2Medical Genetics, University of British Columbia, Vancouver, BC B1270/P650 SHARPIN modulates ligandspecific mechanosensing through regulation of integrin binding dynamics. M. Lerche1, E. Peuhu1, A. Elosegui2, P. Roca-Cusachs2,3, J. Ivaska1,4; 1University Of Turku, Centre for Biotechnology, Turku, Finland, 2Institute for Bioengineering of Catalonia, Barcelona, Spain, 3University of Barcelona, Barcelona, Spain, 4Biochemistry and Food Chemistry, University of Turku, Turku, Finland B1271/P651 Vimentin regulates integrinmediated cell migration by directly binding to integrin β subunits through Ser38 residue. J. Kim1, E. Kim1, C. Yang1,2, C. Kim1; 1Department of Life Science, Korea University, Seoul, Korea, South, 2School of Biological Science, Seoul National University, Seoul, Korea, South B1272/P652 Discoidin Domain Receptor 1 Enables Collagen Remodeling by CellMediated Traction Forces. N.M. Coelho1, P.D. Arora1, S. VanPutten1, S. Boo1, P. Petrovic1, B. Hinz1, C.A. McCulloch1; 1Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, Toronto, ON

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1273/P653 Type IV Collagen stabilizes the connection of juxtaposed tissues at the B-LINK complex. D.P. Keeley1, D.R. Sherwood1; 1Biology, Duke University, Durham, NC B1274/P654 Protein Interactions in the Core Adhesome and the Origins of Animal Multicellularity. E.A. Carter1, R.O. McCann1; 1Basic Medical Sciences, Mercer University School of Medicine, Macon, GA

B1276/P656 The involvement of Lu/B-CAM spectrin binding motif in cell migration on LM-511. N. Harashima1; 1Clinical Biochemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan B1277/P657 Role of focal adhesion kinase signaling in vascular smooth muscle cell migration, proliferation, and intimal hyperplasia. J. Kim1, H. Park2, H. Kong1, J.M. Murphy2, D.D. Schlaepfer3, E. Ahn1, S. Lim2; 1Mitchell Cancer Institute, University of South Alabama, Mobile, AL, 2Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, 3Moores Cancer Center, University of California, San Diego, La Jolla, CA B1278/P658 HAI-2-SPINT2 regulates HGF and CXCL12 secretion in stromal cells and increases cell adhesion. F.M. Roversi1,2, R.G. Rosa1, G.P. Santos1, A.D. Duarte1, A. Longhini1, S.T. Saad1; 1Hematology and Hemotherapy Center, University of Campinas, Campinas, Brazil, 2Universidade São Francisco, Bragança Paulista, Brazil B1279/P659 Effect of titanium surface topography on integrin signaling pathway and osteoblast genotype expression. H.B. Lopes1, C.N. ELIAS2, P.T. OLIVEIRA1, A.L. ROSA1, M.M. Beloti1; 1Cell Culture Laboratory, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil, 2 Materials Science Department, Military Institute of Engineering, Rio de Janeiro, Brazil B1280/P660 A plasmid-based MMP14-FAP biosensor for monitoring and measuring MMP14 activity in real-time. A. Braun1, K.A. Myers1; 1Biology, University of the Sciences in Philadelphia, Philadelphia, PA B1281/P661 Procaspase-3 regulates the apoptotic threshold of the cell through modulation of fibronectin secretion. D.B. Weir1, L.H. Boise2; 1Cancer Biology Graduate Program, Emory University, Atlanta, GA, 2Hematology and Medical Oncology, Emory University, Atlanta, GA

B1282/P662 Coordinated integrin activation by actin-dependent force during T cell migration. P. Nordenfelt1,2,3, H.L. Elliott3, T.A. Springer1; 1BCMP, Harvard Medical School, Boston, MA, 2Infection Medicine, Lund University, Lund, Sweden, 3Image and Data Analysis Core, Harvard Medical School, Boston, MA B1283/P663 Characterization of the interacting moieties of αX I domain and Receptors for Advanced Glycation End Products (RAGE). S. Nham1, B. Dolgorsuren1; 1Science Education, Kangwon National University, Chuncheon, Korea, South B1284/P664 Extracellular Matrix Downregulation in the Drosophila Heart Preserves Contractile Function and Improves Lifespan. A.O. Sessions1, G. Kaushik2, S. Parker3, K. Raedschelders3, R. Bodmer4, A.J. Engler2; 1Biomedical Sciences Program, University of California, San Diego, La Jolla, CA, 2Bioengineering, University of California, San Diego, La Jolla, CA, 3Advanced Clinical Biosystems, Cedars-Sinai Heart Institute, Los Angeles, CA, 4Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA B1285/P665 Intracellular and extracellular calreticulin are required for extracellular matrix and integrin induction by a complex mechanism essential for tissue regeneration and wound healing. U.M. Pandya1, J. Daubriac2, C. Jaramillo2, C. Egbuta2, A. Tellechea2, L.I. Gold1; 1Medicine and Pathology, New York University School of Medicine, New York, NY, 2Medicine, New York University School of Medicine;Langone Medical Center, New York, NY B1286/P666 Spatiotemporal regulation of focal adhesions disassembly at the G2/M transition of the cell cycle. H.R. Thiam1, C.M. Waterman1; 1National Heart Lung and Blood Institute, National Institute of Health, Bethesda, MD B1287/P667 MARVELD1 knockout mice exhibit Trophoblast cell hyperinvasion. H. Zhang1, Y. Chen1, F. Han1, Y. Li1; 1Harbin Institute of Technology, School of life science and technology, Harbin, China B1288/P668 The integrin-associated kinase Abl2/Arg weakens endothelial cellmatrix adhesion and enhances barrier disruption in inflammatory edema. E. Valent1, J.M. Azevedo1, J. van Bezu1, E. Eringa1, F.M. Hoevenaars1, K. Nawaz2, P.L. Hordijk1, V.W. van Hinsbergh1, G.P. van Nieuw Amerongen1, C. Margadant2, J. Aman1; 1Department of Physiology, Institute for Cardiovascular Research, VU Medical Center, Amsterdam, Netherlands, 2 Molecular Cell Biology, Sanquin Research, Amsterdam, Netherlands

Cell Death B1301/P670 What does Bax do if it is unable to go to mitochondria? A. Mañas1, S. Wang2, H. Zhang1, N. Maltsev2, J. Xiang1; 1Department of Biology, Illinois Institute of Technology, Chicago, IL, 2Human Genetics Department, Computation Institute, University of Chicago, Chicago, IL B1302/P671 Carbon Black Exposure Induces Alterations in Mitochondrial Morphology in Human Lung Cells: A Software-Based Quantitative Analysis. J.L. Brewster1, J.D. Duff1, B.K. Laferney1, C.Y. Jones1, P.M. Mcclatchey2; 1Natural Science Division, Pepperdine University, Malibu, CA, 2Department of Pharmacology, University of Colorado, Aurora, CO B1303/P672 Oxidation of vitamin C induces neuronal death and alterations in distribution of GLUT1/ SVCT2 and mitochondrial size. L. Ferrada1, C. Albarran1, K.A. Salazar 1, F.J. Nualart1; 1Concepcion University, Center for advanced microscopy, CMA BIOBIO, Concepcion, Chile B1304/P673 Role of the prodomain of caspase-3 in apoptotic activity. K.G. Ponder1, L.H. Boise2; 1Cancer Biology Graduate Program, Emory University, Atlanta, GA, 2Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA B1305/P674 Caspase-independent granulosa cell death in Wistar rat’s ovaries. O.M. Echeverría1, N. Torres1, M.L. Escobar1, G.H. Vázquez-Nin1; 1Biología Celular, Facultad de Ciencias, Ciudad de México, Mexico B1306/P675 Mechanism of Pro-apoptotic Death Receptor 5 Activation by the Unfolded Protein Response. M. Lam1, A. Ashkenazi2, P. Walter1; 1Howard Hughes Medical Institute, Biochemistry, University of California at San Francisco, San Francisco, CA, 2Genentech Inc, South San Francisco, CA B1307/P676 Phosphorylation of the RNAinduced silencing complex protein, TRBP, regulates PKR activity during cell stress. E.E. Chukwurah1, R.C. Patel1; 1Department of Biological Sciences, University of South Carolina, Columbia, SC B1308/P677 Mycobacterial killing effect of M1-polarized macrophages by induction of endoplasmic reticulum stressmediated apoptosis. Y. Lim1,2, J. Choi1,2, J. Lee1,2, S. Cho1,2, S. Oh1,2, S. Kim1,2, D. Go1,2, C. Song1,2; 1Department of Medical Science, College of Medicine, Chungnam National University, Daejeon, Korea, 2Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South

B1289/P669 Integrin-linked interaction of oogonial stem cells with the extracellular matrix (ECM): implications for germline differentiation. J.A. MacDonald1, D.C. Woods1, J.L. Tilly1; 1Biology, Northeastern University, Boston, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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B1275/P655 Hybrid computational modeling of collective cell durotaxis. J. Escribano1, R. Sunyer2, P. RocaCusachs2,3, X. Trepat2,3, J.M. García Aznar1; 1Mechanical Engineering, University of Zaragoza, Zaragoza, Spain, 2Institute for Bioengineering of Catalonia, Barcelona, Spain, 3University of Barcelona, Barcelona, Spain

Sunday Poster Session

Board No./Presentation No. B1309/P678 Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 element. M. Dery1,2, A.C. LeBlanc1,2; 1Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, 2Neurology and Neurosurgery, McGill University, Montreal, QC B1310/P679 Thioredoxin-1 inhibition promotes MLKL oligomerization and necroptosis. E. Reynoso Moreno1, Z. Wang, Ph.D.1; 1Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX B1311/P680 Unsaturated carbonyl compounds in the gas phase of cigarette smoke induces cell death through intracellular Ca2+-dependent PKC activation. T. Higashi1, Y. Mai1, Y. Mazaki1, T. Horinouchi1, S. Miwa1; 1Department of Cellular Pharmacology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan B1312/P681 Effect of the phthalate, benzylbutylphthalate (BBzP), on neuron viability using Neuro 2a Cells. V.L. Hernandez1, H. Dowell1, N. Bergstrom1, A.K. Binder1, L. Carnell1; 1Biological Sciences, Central Washington University, Ellensburg, WA B1313/P682 Accentuation of glycolysis of vascular endothelial cell under the hypoxia by activation peptide of coagulation factor IX. A. Mamiya1, H. Kitano1, Y. Fujiwara1,2, T. Ishikawa1, E. Yamamoto1,2, C. Hidai2; 1Oral Surgery, Nihon Univ., Tokyo, Japan, 2Physiology, Nihon University, Tokyo, Japan B1314/P683 Prevention effect of the extract of Allium Tuberosum on vascular inflammation in tumor necrosis factor-αinduced human umbilical vein endothelial cells (HUVEC). A. LEE1; 1Division of Functional Food Research, Korea Food Research Institute, Seongnam, Korea, South B1315/P684 Effects of Cryo Preservation on Oxidative Stress and Antioxidant Enzyme Activity in Spermatozoa of Atlantic Salmon (Salmo salar). E. Figueroa1, M. Lee-Estevez1, J. Risopatron2, I. Valdebenito3, R. Pinheiro de Souza 4, J.G. Farias1; 1Chemical Engineering, Universidad de La Frontera, Temuco, Chile, 2Center for Biotechnology in Reproduction, Universidad de La Frontera, Temuco, Chile, 3School of Aquaculture, Universidad Católica de Temuco, Temuco, Chile, 4Biochemical and Pharmaceutical Technology, University of São Paulo, Sao Paulo, Brazil B1316/P685 Mild Hyperthermia Induces Apoptosis in Metaphase-Arrested H-HeLa Cells but not in Interphase Cells. J.R. Paulson1, A.K. Kresch2, P.W. Mesner3; 1Chemistry, University of Wisconsin-Oshkosh, Oshkosh, WI, 2 Prevea St. Mary’s Health Center, Green Bay, WI, 3Biology, University of WisconsinWhitewater, Whitewater, WI

Sunday Poster Session Induced Apoptosis in Cardiomyocytes. J.L. Major1, B. Tuana1,2, M. Salih1; 1Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, 2Heart Institute, University of Ottawa Heart Institute, Ottawa, ON B1318/P687 Nuclear localization of BLM-s by Ku70 to effect inactivation of BLM-s-mediated apoptosis. M. Tsai1, P. Huang1; 1National Taiwan University, Graduate Institute of Pathology, College of Medicine, Taipei, Taiwan B1319/P688 Modulation of tunicamycininduced ER stress and cell death by globular adiponectin in primary rat hepatocytes. A. Khakurel1, N. Tilija Pun1, P. Raut1, E. Kim1, H. Oh1, A. Shrestha1, P. Park1; 1College of Pharmacy, Yeungnam University, Gyeongsan, Korea, South B1320/P689 Estrogen-induced cytotoxicity and epigenetic regulation in Japanese eel follicle cells. Y. Hsieh1, T. Lin1, Y. Wang1; 1Institute of Fisheries Science, National Taiwan University, Taipei, Taiwan B1321/P690 The Parkinson’s Disease Protein α-synuclein Αlters the Microenvironment of the Εndoplasmic Reticulum in Saccharmomyces cerevisiae. T.J. McBride1, N. Austriaco1; 1Biology, Providence College, Providence, RI B1322/P691 Protective effects of Korean medicinal plants against oxidative stressinduced cell death in retinal pigment epithelium cells. M. Kim1; 1Research Group of Food Functionality, Korea Food Research Institute, Sungnam-si, Korea, South B1323/P692 HSPA13 Bifurcates TNFainduced NF-kB and Death Responses. C. GAO1, X. Feng1; 1Life Sciences Institute Zhejiang University, Hangzhou, China

Chaperones, Protein Folding, and Quality Control 1 B1324/P693 The chaperone complex BAG3HSPB8 as a novel target of CDK1-cyclin B in remodeling of mitotic actin-based structures that guide spindle orientation. C. Luthold1, H. Lambert1, M. Fuchs1, J.N. Lavoie1,2; 1Axe oncologie, Hotel de Dieu de Quebec, Centre de recherche sur le cancer de l Université Laval, Quebec, Canada, 2 Biologie moléculaire, biochimie médicale et pathologie, Faculté de medecine, Université Laval, Quebec, Canada B1325/P694 Response of cultured mammalian cells to extreme cold shock and subsequent rewarming: expression of the eukaryotic chaperonin CCT and the cytoskeletal proteins. A.M. Velho1; 1School of Nursing, Canterbury Christ Church University, Canterbury, United Kingdom B1326/P695 Determining the essential

binding partner of the yeast auxilin homolog Swa2 in [URE3] prion propagation. E.E. Oliver1, J.K. Hines1; 1Chemistry, Lafayette College, Easton, PA B1327/P696 Mediating cellular desiccation tolerance with intrinsically disordered proteins. T.C. Boothby1,2, S. Piszkiewicz2, A. Mehta2, A.H. Brozena3, H. Tapia4, D.E. Koshland4, B. Goldstein1, G.J. Pielak2; 1Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 4Biology, University of California, Berkeley, Berkeley, CA B1328/P697 TrkB activator LM22A enhances GAP43 phosphorylation to attenuate neuronal activity blockadeinduced gephyrin misfolding. W. Chien1, C. Lee1, Y. Lee1; 1Physiology and Brain Research Center, National Yang-Ming University, Taipei, Taiwan B1329/P698 The Role of MAP Kinase Pathways in a Yeast Model of Huntington’s Disease. Y. Jiang1, J. Genereaux1, P. Lajoie1; 1Anatomy and Cell Biology, University of Western Ontario, London, ON B1330/P699 A novel amyloid-specific proteostasis pathway mediated by Hsp30 results in cytosolic vitrification. T.S. Kandola1, J.J. Lange1, R. Halfmann1,2; 1Stowers Institute for Medical Research, Kansas City, MO, 2Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS B1331/P700 Three complementary mechanisms of quality control ensure RNP granule functionality and dynamics. D. Mateju1, E. Boczek1, J. Wang1, A. Kopach1, S. Maharana1, A. Patel1, H.O. Lee1, M. Jahnel1, S.W. Grill1, A.A. Hyman1, S. Alberti1; 1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B1332/P701 Role of folding intermediates in initiating aggregation of the prion protein. R. Moulick1, R.R. Goluguri1, J.B. Udgaonkar1; 1National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bengaluru, India B1333/P702 Reciprocal effects of Hsp40 expression in Hsp104-mediated prion elimination. E. Kamiya1, S.E. Berger1, M.T. Astor1, J.K. Hines1; 1Chemistry, Lafayette College, Easton, PA B1334/P703 Variant-specific Hsp40 functions in Hsp104-mediated prion elimination: A potential role for ‘Antiprion DnaJ’ (Apj1). M.T. Astor1, E. Kamiya1, J.K. Hines1; 1Chemistry, Lafayette College, Easton, PA B1335/P704 Evolutionary conservation

B1317/P686 E2F6 Protects Against Stress

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The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. of variant-dependent prion-promoting Hsp40 functions in plants. J.K. Hines1, R.E. Brown1; 1Chemistry, Lafayette College, Easton, PA B1336/P705 Protein aggregation as a means of dosage compensation. S. Venkatesan1, M. Wilkinson2, R. Halfmann1,3; 1Stowers Institute for Medical Research, Kansas City, MO, 2Department of Molecular Biology, University of Kansas, Lawrence, KS, 3Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS

B1338/P707 Cytosolic Proteostasis via Importing of Misfolded Proteins into Mitochondria. L. Ruan1, C. Zhou2, E. Jin1, A. Kucharavy1, Y. Zhang2, Z. Wen2, L. Florens 2, R. Li1; 1Cell Biology, Johns Hopkins University, Baltimore, MD, 2Stowers Institute for Medical Research, Kansas City, MO B1339/P708 Specific serine phosphorylation of IRE-1 controls enhanced splicing of XBP-1 and RIDD. C.A. Tang1, S. Chang1, A.W. Paton2, J.C. Paton2, D.I. Gabrilovich1, H.L. Ploegh3, J. Del Valle4, C.A. Hu1; 1The Wistar Institute, Philadelphia, PA, 2Department of Molecular and Cellular Biology, University of Adelaide, Adelaide, Australia, 3Whitehead Institute for Biomedical Research, Cambridge, MA, 4 Department of Chemistry, The University of South Florida, Tampa, FL B1340/P709 Yeast Bax Inhibitor (BXI1) Is Involved in Calcium Homeostasis of the ER in Saccharomyces cerevisiae. L. McDonough1, N. Austriaco1; 1Biology, Providence College, Providence, RI B1341/P710 Reversible aggregation of pyruvate kinase regulates cell cycle restart after stress. S. Saad1,2, G. Cereghetti2,3, Y. Feng2,3, P. Picotti2, R. Dechant2,4, M. Peter2,4; 1Life Science Zurich PhD Program, Molecular and Translational Biomedicine, Zurich, Switzerland, 2ETH Zurich, Institute of Biochemistry, Zurich, Switzerland, 3Life Science Zurich PhD Program, Molecular Life Science, Zurich, Switzerland, 4Corresponding author, Zurich, Switzerland B1342/P711 License to Kill: The Clearance of Cytosolic Misfolded Proteins. S. Comyn1, M. Zhu1, A. Rose1, T. Mayor1; 1Michael Smith Laboratories, University of British Columbia, Vancouver, BC

Outputs of Ire1 in S. cerevisiae and S. pombe. W. Li1, V. Okreglak1, P. Kimmig1,2, J. Peschek1, P. Walter1,3; 1Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, 2Institute of Biochemistry, ETH Zurich, Zurich, Switzerland, 3Howard Hughes Medical Institute, San Francisco, CA

Physical Approaches to Cell Biology B1345/P713 The liquid to gel transition in protein droplets. L. Jawerth1,2, M. Ijavi2, E. Fischer-Friedrich1,2, S. Saha2, F. Julicher1, A.A. Hyman2; 1Biophysics, Max Planck Institute for the physics of complex systems, Dresden, Germany, 2Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B1346/P714 Molecular basis of lowdensity RNA/protein droplets revealed with ultra-fast fluorescence correlation spectroscopy. M. Wei1, S. ElbaumGarfinkle1, A.S. Holehouse2, C.C. Chen1, M. Feric1, C.B. Arnold3, R.D. Priestley1, R.V. Pappu2, C.P. Brangwynne1; 1Chemical and Biological Engineering, Princeton University, Princeton, NJ, 2Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, 3Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ B1347/P715 Mechanisms underlying cargo transport through MT-MT intersections. J. Bergman1, A. Takshak2, A. Kunwar2, M. Vershinin1,3,4; 1Biology Department, University of Utah, Salt Lake City, UT, 2 Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India, United States, 3Physics Department, University of Utah, Salt Lake City, UT, 4 Center for Cell and Genome Science, University of Utah, Salt Lake City, UT B1348/P716 Rapid manipulating cellular activities by an ultrasound-chemical hybrid system. C. Fan1, W. Huang2, Y. Huang3, A.A. Lee4, C. Wang3, T. Ueno5, T. . Wang4, C. Yeh1, Y. LIN3; 1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, HsinChu City, Taiwan, 2Department of Life Science, National Tsing Hua University, HsinChu City, Taiwan, 3Institute of Molecular Medicine, National Tsing Hua University, HsinChu City, Taiwan, 4Department of Chemistry, National Taiwan University, Taipei, Taiwan, 5Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan B1349/P717 Frequency Modulation of

ERK activation dynamics rewires cell fate. H. Ryu1, M. Chung1, M. Dobrzynski2, D. Fey3, Y. Blum2, S. Lee4, M. Peter4, B. Kholodenko3, N. Jeon1, O. Pertz2; 1School of Mechanical and Aerospace Engineering, Seoul National University, Seoul, Korea, 2 Institute of Cell Biology, University of Bern, Bern, Switzerland, 3System Biology Ireland, University College Dublin, Dublin, Korea, 4 Institute of Biochemistry, ETH Zurich, Aurich, Switzerland B1350/P718 Using single cell proteomics to identify and classify protein-protein relationships. K.M. Kovary1, M. Teruel1, M.L. Zhao1; 1Chemical and Systems Biology, Stanford University, Stanford, CA B1351/P719 Profiling of cellular morphodynamic behavior based on spatiotemporal spectrum decomposition and clustering. X. Ma1, O. Dagliyan2, K.M. Hahn2, G. Danuser1; 1Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, 2Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC B1352/P720 Diffusion of DNA-binding species in the nucleus: the transient anomalous subdiffusion model. M.J. Saxton1; 1Biochemistry & Molec Med, University of California, Davis, Davis, CA B1353/P721 Mapping of tissue strain during zebrafish gastrulation. D. Bhattacharya1,2,3, J. Zhong1,2, A.J. Kabla4, P.T. Matsudaira1,2; 1Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 2Center for Bioimaging Sciences, National University of Singapore, Singapore, Singapore, 3Singapore-MIT Alliance for Research and Technology, National University of Singapore, Singapore, Singapore, 4Engineering Department, Mechanics and Materials Division, University of Cambridge, Cambridge, United Kingdom B1354/P722 Spontaneous Compartmentalization Selectively Entraps Intracellular Proteins under a Macromolecular Crowding Condition: Self-Emergence of Cell-Like Structure. N. Nakatani1, K. Tsumoto2, K. Takiguchi3, M. Hayashi3, S. Tanaka3, C.Y. Shew4, K. Yoshikawa1; 1Department of Life Physics, Doshisha University, Kyoto, Japan, 2 Graduate School of Engineering, Mie University, Mie, Japan, 3Division of Biological Science, Nagoya University, Nagoya, Japan, 4 Department of Chemistry, College of Staten Island, City University of New York, New York, NY B1355/P723 Mitochondrial fluctuations as a measure of biomechanical properties of murine cells. W. Xu1, E. Alizadeh1, J. Castle2, A. Prasad1; 1Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, 2Biology, Colorado State University, Fort Collins, CO B1356/P724 Design principles of robust

B1343/P712 Dissecting Distinct Functional

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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SUNDAY

B1337/P706 Assessing the role of endoplasmic stress signaling pathways in chronological aging. S.R. Chadwick1, E.N. Fazio2, P. Lajoie1, M.L. Duennwald3; 1Anatomy Cell Biology, University of Western Ontario, London, ON, 2 London Regional Cancer Program, London Health Sciences Centre, London, ON, 3 Pathology Laboratory Medicine, University of Western Ontario, London, ON

Sunday Poster Session

Board No./Presentation No. vesiculation in clathrin-mediated endocytosis. J.E. Hassinger1, G. Oster2, D.G. Drubin2, P. Rangamani3; 1Biophysics, University of California, Berkeley, Berkeley, CA, 2Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 3 Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, CA B1357/P725 Protective effect of DMSO on DNA double-strand break among different lesions: gamma-ray, photoinduced active oxygen and freezing. M. Noda1, Y. Yoshikawa2, T. Imanaka2, T. Mori3, M. Furuta3, T. Kenmotsu1, T. Tsuruyama4, K. Yoshikawa1; 1Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan, 2Research Organization of Science and Technology, Ritsumeikan University, Kusatsu, Japan, 3Osaka Prefecture University, Department of Quantum and Radiation Technology, Sakai, Japan, 4 Graduate School of Medicine, Pathological and Forensic Medical Researches, Kyoto, Japan B1358/P726 RNA gelation in repeat expansion disorders. A. Jain1, R.D. Vale1; 1University of California, San Francisco, San Francisco, CA B1359/P727 The Role of Compressive Load on Adipogenic Differentiation of 3T3L1 Cells. A.C. Areias1, C. Silvestri1, D.R. Overby1; 1Bioengineering, Imperial College London, London, United Kingdom B1360/P728 Boundary effects in FRAP recovery in the confined geometries of animal, plant and fungal cells. J.L. Kingsley1, J.P. Bibeau2, C. Unsal1, S.I. Mousavi1, Z. Chen3, X. Huang3, L. Vidali2, E. Tuzel1; 1Department of Physics, Worcester Polytechnic Institute, Worcester, MA, 2 Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, 3Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA B1361/P729 Experimental and computational methodologies to measure intercellular forces during tissue development. E. Criado-Hidalgo1, Y. Yeh1, R. Serrano1, J.C. Del Alamo1, J.C. Lasheras1; 1Mechanical and Aerospace Engineering, University of California San Diego, San Diego, CA

Sunday Poster Session

Systems and Synthetic Biology, and Tissue Engineering B1362/P730 Biochemical modulation of a reconstituted protein oscillator. S. Kretschmer1,2, K. Zieske1,3, P. Schwille1; 1Cellular and Molecular Biophysics, Max-Planck-Institute of Biochemistry, Martinsried, Germany, 2 Graduate School of Quantitative Biosciences, Ludwig-MaximiliansUniversität, München, Germany, 3 Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA B1363/P731 Development of synthetic biological tools for use in technologylimited settings. J.L. Luther1, R.A. Miller1, A.A. Weaver2, H.V. Goodson1, M. Lieberman1; 1Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 2Civil & Envr Engr & Earth Sciences, University of Notre Dame, Notre Dame, IN B1364/P732 Using optogenetics to uncover principles governing cell size scaling relationships in giant yeast. C. Allard1,2, F. Decker1,3, O.D. Weiner1,4, B.R. Graziano1,4, J.E. Toettcher1,5; 1Marine Biological Laboratory, Woods Hole, MA, 2Department of Biochemistry, Dartmouth Medical School, Hanover, NH, 3Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 4Cardiovascular Research Institute, UCSF, San Francisco, CA, 5Department of Molecular Biology, Princeton University, Princeton, NJ B1365/P733 Reconstituting the mammary stem cell niche. L.M. Murrow1, Z.J. Gartner1,2; 1Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 2Center for Systems and Synthetic Biology, University of California San Francisco, San Francisco, CA B1366/P734 3D confined tubular epithelia in microfluidic channels. L. Alaimo1, S. Gabriele1; 1Mechanobiology and Soft Matter Group - Influx, UMons, Mons, Belgium B1367/P735 Role of Antibiotic Interactions in Modulating E. Faecalis Resistance Evolution. Z. Dean1, K. Wood1,2; 1Department of Biophysics, University of Michigan at Ann Arbor, Ann Arbor, MI, 2Department of Physics, University of Michigan at Ann Arbor, Ann Arbor, MI B1368/P736 Coordinated translational regulation in cellular quiescence. S. Sun1; 1Biology, New York University, NYC, NY B1400/P737 Optogenetic platform to probe spindle positioning and cytokinesis signaling in vitro. J.G. Bermudez1, M.C. Good1; 1Bioengineering, University of Pennsylvania, Philadelphia, PA

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B1401/P738 Optogenetic Triggering of Protein Localization and Activity in a Synthetic Cell System. R.M. Caldwell1,2, D.G. Thai1,2, J.G. Bermudez2, M.C. Good1,2; 1Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA, 2 Department of Bioengineering, University of Pennsylvania, Philadelphia, PA B1402/P739 An artificial cell-like system for the study of symmetry breaking in living cells. P. Torre1, M. Good1, J.G. Bermudez1; 1Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA B1403/P740 Development of epitope barcoding for high-throughput imagebased genetic screening. T. Kudo1, M.W. Covert2; 1Chemical and Systems Biology, Stanford University, Stanford, CA, 2Bioengineering, Stanford University, Stanford, CA B1404/P741 Using Optogenetics to study Ras Activation in Lymphocytes at Single Cell Resolution. J.D. Mclaurin1, O.D. Weiner1; 1Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA

Germ Cells, Gametogenesis, and Fertilization B1406/P742 Calcineurin interacting protein regulates reproduction processes in C. elegans. H. Jung1, J. Ahnn1, S. Lee1, S. Durnaoglu1; 1Life Science BK21Plus Biodefence, Hanyang University, Seoul, Korea, South B1407/P743 A Sterile 20 family kinase regulates oogenesis by tuning contractile ring proteins on germline intercellular bridges. K.N. Rehain1, A.C. Love2, M. Werner2, I. Macleod3, J. Yates iii3, A.S. Maddox2; 1Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, 2Biology, University of North Carolina, Chapel Hill, NC, 3Chemical Physiology, The Scripps Research Institute, La Jolla, CA B1408/P744 The sperm-derived TRP family channel TRP-3 induces a calcium rise in the fertilized oocyte in C. elegans. J. Takayama1, H. Okada1, S. Onami1; 1RIKEN QBiC, Kobe, Japan B1409/P745 A Lysosomal Switch Renews Germline Proteostasis in C. elegans. A. Bohnert1,2, C. Kenyon1,2; 1Biochemistry Biophysics, University of California, San Francisco, San Francisco, CA, 2Calico Life Sciences, South San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1410/P746 Meiotic chromosome cohesion promotes germline immortality. K. Billmyre1,2, A. Doebley1,2, S. Flibotte3, M. Simon1,2, D. Moerman3, S. Ahmed1,2; 1Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, 2 Department of Biology, University of North Carolina-Chapel Hill, Chapel Hill, NC, 3 Department of Zoology, University of British Columbia, Vancouver, BC

B1412/P748 Genetic dissection of Cyclin A/ Cdk1 regulation by Myt1 kinase during Drosophila male meiosis. R. Varadarajan1, R. Willms1, S.D. Campbell1; 1Biological Sciences, University of Alberta, Edmonton, AB B1413/P749 Determination of the role of Dreadlocks (Dock) in the growth of the germline ring canals in the developing Drosophila melanogaster egg chamber. O. Crowe1, L. Lewellyn1; 1Biology, Butler University, Indianapolis, IN B1414/P750 Characterizing a Role for the Misshapen Kinase in the Growth of the Germline Ring Canals in the Developing Egg Chamber. A.N. Kline1, L. Lewellyn1; 1Department of Biology, Butler University, Indianapolis, IN B1415/P751 The interaction between Piwi and c-Fos regulate ovarian germline stem cells and ovarian somatic stem cells in the Drosophila ovarian germline. J.D. Klein1, C. Qu1, X. Yang1, J.C. Peng1; 1Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, TN B1416/P752 Cytoplasmic Gas6 is a key player for sperm chromatin decondensation in mammalian oocytes via Ndst-heparan sulfate (HS) pathway and mitochondrial overactivation. K. Kim1, E. Kim1, S. Lee1, J. Ko1, K. Lee1; 1Department of Biomedical Science, College of Life Science, CHA University, Pangyo, Korea, South B1417/P753 Estrogenic compounds impair primordial follicle formation by inhibiting the expression of proapoptotic Hrk in neonatal rat ovary. H. Zhang1,2, K. Nagaoka1,2, K. Usuda1,2, K. Nozawa2, K. Taya1, M. Yoshida3, G. Watanabe1,2; 1United Graduate School of Veterinarian Science, Gifu University, Gifu, Japan, 2, Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo, Japan, 3 Division of Pathology, National Institute of Health Sciences, Tokyo, Japan

B1418/P754 In vitro development of marmoset ovarian follicles in the presence of anti-apoptotic factors. S. Ku1, Y. Kim1, Y. Kim2, J. Yun3, B. Kang3; 1Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea, South, 2 Department of Obstetrics and Gynecology, Korea University Medical College, Seoul, Korea, South, 3Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea, South B1419/P755 Participation of deubiquitinating activity in porcine fertilization and zygotic development. Y. Yi1, P. Sutovsky2; 1Division of Biotechnology, Chonbuk National University, Iksan, Korea, South, 2Division of Animal Sciences, University of Missouri, Columbia, MO B1420/P756 Unconventional Endocannabinoid Signaling in Male Fertility and Beyond. I. Björkgren1, A.J. Modzelewski1, S. Chen1, M. Bogaczynska1,2, M.R. Miller1, P.V. Lishko1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2HAN University of Applied Sciences, Nijmegen, Netherlands B1421/P757 Inactivation of the Sodium (Na+)/Hydrogen (H+) exchanger NHE5 to Determine its Roles in Sperm Physiology. J.S. Powers1, B. Wagner1, B. McElderry1, M. Amigo1, G. VanNess1, P.F. James1; 1Biology, Miami University, Oxford, OH B1422/P758 Search of capacitation-related surface proteins in mouse sperm by differential fluorescent two-dimension electrophoresis. O. Suzuki1, M. Koura1, K. Uchio-Yamada1, M. Sasaki1; 1Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki-shi, Japan B1423/P759 A Somatic Temporal Switch In The Mode Of Wnt Signaling Controls Germline Development In Drosophila. M. Upadhyay1, M. Kuna1, S. Tudor1, P. Rangan1; 1Biological Sciences/RNA Institute, University at Albany, SUNY, Albany, NY

Cell-Cell Interactions in Tissue Development and Morphogenesis B1424/P760 Self-organization of skin organoid with hair primordia formation in vitro. M. Lei1,2, L. Schumacher3, Y. Lai4, W. Juan4, C. Yeh2, P. Wu2, T. Jiang2, R. Baker3, R. Widelitz2, L. Yang1, C. Chuong2,4; 1College of Bioengineering, Chongqing University, Chongqing, China, 2Department of Pathology, University of Southern California, Los Angeles, CA, 3Mathematical Institute, University of Oxford, Oxford, United Kingdom, 4Integrative Stem Cell Center, China Medical University, Taichung, Taiwan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1425/P761 Heterotypic cell interactions maintain the secretory acinar phenotype in submandibular salivary glands. Z. Farajallah Hosseini1, L.M. Sfakis2, D.A. Nelson1, J. Castracane2, M. Larsen1; 1Biological Sciences, State University of New York at Albany, Albany, NY, 2Colleges of Nanoscale Sciences and Engineering, SUNY Polytechnic Institute, Albany, NY B1426/P762 The balance between N-cadherin and E-cadherin orchestrates major neuroectodermal cell fate choices. C.D. Rogers1, L. Sorrells Smith1, M.E. Bronner2; 1Biology, California State University Northridge, Northridge, CA, 2 Biology and Bioengineering, California Institute of Technology, Pasadena, CA B1427/P763 RhoGTPases and Mesenchymal-to-Epithelial Transitions: same legs (actin), but different shoes (cadherins vs. integrins). C.P. Toret1, P.C. Shivakumar1, P. Lenne1, A. Le Bivic1; 1IBDM, AMU-CNRS, Marseilles, France B1428/P764 Promiscuous adhesion inhibits multicellular development in the choanoflagellate S. rosetta. L.A. Wetzel1, N. King1; 1Molecular and Cell Biology, UC Berkeley, Berkeley, CA B1429/P765 Tight coupling between abscission timing and maintenance of permeability barrier during cytokinesis in epithelial tissues. R. Le Borgne1, E. Daniel1, I. Kolotueva1, V.J. Auld2; 1Epithelia Dynamics and Mechanics, CNRS UMR 6290-Institute of Genetics and Development, Rennes, France, 2Department of Zoology, Life Sciences Institute, University of British Columbia, Vancouver, Canada B1430/P766 The balance between cells with distinct spindle dynamic behaviors is maintained by negative feedback during airway tube morphogenesis. Z. Tang1, Y. Hu2, K. Jiang1, C. Zhan1, W.F. Marshall3, N. Tang1; 1 National Institute of Biological Sciences, Beijing, Beijing, China, 2Zhou Pei-yuan Center for Applied Mathematics, Tsinghua University, Beijing, Beijing, China, 3Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B1431/P767 Biomechanical analysis of cell behaviors during neural plate convergent extension. D.S. Vijayraghavan1, J.H. Shawky1, L.A. Davidson1,2,3; 1Bioengineering, University of Pittsburgh, Pittsburgh, PA, 2 Developmental Biology, University of Pittsburgh, Pittsburgh, PA, 3Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA

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SUNDAY

B1411/P747 Roles for retinoic acid receptor alpha (RARA) in male germ cells. N. Peer1, S. Law1, K. Kim1; 1School of Molecular Biosciences, Washington State University, Pullman, WA

Sunday Poster Session

Board No./Presentation No. B1432/P768 Oxidative stress polarizes junctions and the cytoskeleton to drive embryonic wound healing. M.V. Hunter1,2, R. Fernandez-Gonzalez1,2,3,4; 1Cell and Systems Biology, University of Toronto, Toronto, ON, 2Ted Rogers Centre for Heart Research, University of Toronto, Toronto, ON, 3Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, 4Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON B1433/P769 Rosettes pattern neuronal tissue during C. elegans embryogenesis. K. Mastronardi1, D. Wernike2, K. Larocque1, A.J. Piekny1; 1Biology, Concordia University, Montreal, QC, 2Oncology, Sainte-Justine Hospital Research Center, Montreal, QC B1434/P770 Regulation of cell shape change by local inhibition of CDC-42 at epithelial junctions. Y. Zilberman1, D. Anderson1, J. Nance1,2; 1Helen L. and Martin S. Kimmel Center for Biology and Medicine, NYU School of Medicine, Skirball Institute, New York, NY, 2Department of Cell Biology, NYU School of Medicine, New York, NY B1435/P771 Cdo deficiency causes cardiomyopathy by abnormal intercellular communication of cardiomyocytes. J. Pyun1,2, M. Jeong1,2, H. Kim1,3, H. Cho1,3, J. Kang1,2; 1Samsung Biomedical Research Institute, Suwon, Korea, South, 2Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea, South, 3 Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Korea, South B1436/P772 Robo has new roles in myoblast fusion, myonuclear positioning and muscle function. M. Azevedo1,2, M.K. Baylies2,3,4; 1GABBA - Graduate Program in Areas of Basic and Applied Biology, Abel Salazar Biomedical Sciences Institute, University of Porto, Porto, Portugal, 2 Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 3Developmental Biology, Gerstner Graduate School, Memorial Sloan Kettering Cancer Center, New York, NY, 4Developmental Biology, Weill Graduate School of Biomedical Sciences, Cornell Medical School, New York, NY B1437/P773 The small GTPase Arf6 regulates sea urchin morphogenesis. N.A. Stepicheva1, M. Dumas1, P. Kobi1, J.G. Donaldson2, J.L. Song1; 1Biological Sciences, University of Delaware, Newark, DE, 2Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD B1438/P774 Study the function of Yap/ Taz in mouse cortical progenitors. S. Kong1; 1Pediatrics, University of Tennessee Health Science Center, Memphis, TN

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Sunday Poster Session B1439/P775 Developmental and salinity related endopolyploidy in the model halophyte Mesembryanthemum crystallinum. B.J. Barkla1, T. Rhodes1; 1Southern Cross Plant Science, Southern Cross University, Lismore, Australia B1440/P776 Biophysical approach to elucidate molecular links between PCP and adhesion/cytoskeleton dynamics. N. Founounou1, R. Farhadifar2, M. Mlodzik1; 1Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 2Department of Applied Physics, Center for Systems Biology, Harvard University, Cambridge, MA B1441/P777 An extremophile choanoflagellate harbors bacteria. K.H. Hake1, N. King1; 1Molecular and Cell Biology, University of California Berkeley, Berkeley, CA B1442/P778 Interaction between Interferon Regulatory Factor 6 (IRF6) and NME1/2 coordinates innate immune response with changes in cell adhesion and polarity in oral epithelia. T.C. Cox1,2, B. Tamasas1,3, E.Y. Chu1,3, M. Parada3, L.L. Cox1,2; 1Center for Developmental Biology Regenerative Medicine, Seattle Children’s Research Institute, Seattle, WA, 2Pediatrics, University of Washington, Seattle, WA, 3Oral Health Sciences, University of Washington, Seattle, WA B1443/P779 Elucidating the Role of even-skipped in Epithelial Sheet Morphogenesis. S.M. Fogerson1, R.D. Mortensen1, D.P. Kiehart1; 1Biology Department, Duke University, Durham, NC B1444/P780 Keratinocytes and Langerhans cells phagocytose axon debris in the skin. J.P. Rasmussen1, O. Hosseinzadeh1, A. Repouliou1, A. Sagasti1; 1Molecular, Cell, and Developmental Biology Department, UCLA, Los Angeles, CA B1445/P781 Analysis of cell-cell interaction during optic fissure closure in the developing mouse eye. A. Pathak1, K. Hofstetter1, J. Kuntz1, D. Burnette2, S. Fuhrmann1; 1Department of Ophthalmology and Visual Sciences, Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, 2Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN

Cell Fate Determination 1 B1446/P782 Amphiregulin is dispensable for redirection of non-mammary cells to a mammary stem cell fate in vivo. A. George1, C. Boulanger1, C. Brisken2, G.H. Smith1; 1Basic Research Laboratory, National Cancer Institution, Bethesda, MD, 2Molecular Oncology, Swiss Institute for Experimental Research, Lausanne, Switzerland

B1447/P783 Differential regulation of epithelial and mesenchymal phenotypes during EMT by master transcriptional regulators. K. Watanabe1; 1Center for Life science technologies, Riken, Yokohama, Japan B1448/P784 Investigating the role of the SWI/SNF chromatin remodeling complex in the differentiation of the invasive phenotype. J.J. Smith1, A.Q. Kohrman1, A. Herrera1, W. Zhang1, D.Q. Matus1; 1Biochemistry & Cell Biology, SUNY - Stony Brook, Stony Brook, NY B1449/P785 Single cell analysis reveals a synergistic relationship between the cell cycle and fat cell differentiation. M.L. Zhao1, Z.B. Nejad1, M. Chung1, M. Teruel1; 1Chemical and Systems Biology, Stanford University, Stanford, CA B1450/P786 Selective effect of Rin1 mutants on insulin signaling during pre-adipocyte differentiation. Y. Huang1, W. Zhang1, M. Veisaga2, M.A. Barbieri3,4,5; 1Chemistry and Biochemistry, FIU, Miami, FL, 2Biomolecular Science Institute, FIU, Miami, FL, 3International Center for Tropical Botany, FIU, Miami, AL, 4 Fairchild Tropical Botanic Garden, Miami, FL, 5Biological Science, FIU, Miami, FL B1451/P787 Meflin is a specific marker for mesenchymal stem cells (MSCs) whose expression is regulated by substrate stiffness. A. Enomoto1, N. Asai1, T. Kobayashi2, N. Nakamura3, M. Takahashi1; 1Department of Pathology, Nagoya University Graduate School of Medicine, Naogya, Japan, 2Department of Physiology, Nagoya University Graduate School of Medicine, Nagoya, Japan, 3 Department of Internal Medicine, Aichi Gakuin University School of Dentistry, Nagoya, Japan B1452/P788 N6-methyladenosine epitranscriptomic control of human erythroid lineage specification. D.A. Kuppers1, S. Arora1, A.R. Lim1, L. Carter1, R.S. Basom1, J.J. Delrow1, B. TorokStorb1, P. Paddison1; 1Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA B1453/P789 Studying the Role of Id proteins In Kupffer Cell Development. G. Mishra1,2, E. Mass3, I. Ballesteros3, F. Geissmann3,4; 1Biochemistry, Mount Holyoke College, South Hadley, MA, 2Summer Undergraduate Research Program, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY, 3 Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 4 Weill Cornell Graduate School of Medical Sciences, New York, NY B1454/P790 Numb regulates somatic cell lineage commitment during early gonadogenesis. Y. Lin1, L. Barske2, T. De Falco3, B. Capel1; 1Cell Biology, Duke University, Durham, NC, 2Stem Cell, USC, Los Angeles, CA, 3Reproductive Sciences, Cincinnati Children, Cincinnati, OH

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1455/P791 Androgens Regulate Connexin26 to Connexin32 Switch in the Epididymis and Ventral Prostate. C. Adam1, D.G. Cyr1; 1INRS-Institut ArmandFrappier, Laval, QC

B1457/P793 Pattern Formation Across the Central Dogma in Development. Y. Kim1, J.P. Bothma2, M. Norstad2, H.G. Garcia1,2,3; 1Biophysics Graduate Group, University of Berkeley at California, Berkeley, CA, 2Department of Molecular and Cell Biology, University of Berkeley at California, Berkeley, CA, 3Department of Physics, University of Berkeley at California, Berkeley, CA

Prokaryotic Cell Biology B1459/P794 Relative rates of surface and volume synthesis set bacterial cell size. L.K. Harris1, J.A. Theriot1; 1Biochemistry, Stanford University, Stanford, CA B1460/P795 Shape-sensing by MreB filaments to orient peptidoglycan synthesis and produce rod shape in Bacillus subtilis. S. Hussain1,2, C. Wivagg1,2, F. Wong3, P. Szwedziak4, T. Izoré4, A. Amir3, J. Löwe4, E.C. Garner1,2; 1Center for Systems Biology, Harvard University, Cambridge, MA, 2Molecular and Cellular Biology, Harvard University, Cambridge, MA, 3 Department of Physics, Harvard University, Cambridge, MA, 4Laboratory of Molecular Biology, Medical Research Council, Cambridge, United Kingdom B1461/P796 Coordination of FtsZ Ring Formation in Bacillus Subtilis. P. Buske1, R.D. Mullins1; 1Cellular and Molecular Pharmacology, HHMI/UCSF, San Francisco, CA B1462/P797 Mechanistic insights of the Min Oscillator via cell-free reconstitution and imaging. A.G. Vecchiarelli1, K. Mizuuchi1; 1National Institutes of Health, Bethesda, MD B1463/P798 FtsZ dynamics and the distribution of cell wall synthesis in bacterial cytokinesis. G.R. Squyres1, A. Bisson1, Y. Hsu2, E. Kuru2, M. Van Nieuwenhze2, Y. Brun3, E.C. Garner1; 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 2Department of Chemistry, Indiana University, Bloomington, IN, 3 Department of Biology, Indiana University, Bloomington, IN

B1464/P799 Structural studies of actin-like filament a (AlfA) and Alf-A driven plasmid segregation. G.D. Usluer1, J.M. Kollman1, E.J. Charles2; 1Biochemistry, University of Washington, Seattle, WA, 2 Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA

B1472/P807 Using fluorescent D-amino acids to probe the activity and regulation of cell wall hydrolases in the Grampositive organism Bacillus subtilis. S.A. Wilson1, E.C. Garner1; 1Molecular and Cellular Biology, Harvard University, Cambridge, MA

B1465/P800 Capsid Trafficking of Pseudomonas Phage 201Phi2-1 to the Phage Nucleus and the Role of the PhuZ Filament in Capsid Transportation. V. Chaikeeratisak1, K.T. Nguyen1, M.L. Erb1, A.D. Vavilina1, M.E. Egan1, J. Pogliano1; 1Biology, University of California, San Diego, San Diego, CA

B1473/P808 Intracellular Trafficking to the Phage Nucleus. K.T. Nguyen1, V. Chaikeeratisak1, K. Khanna1, A.F. Brilot2, D. Agard2, E. Villa1, J. Pogliano1; 1Biological Sciences, UC San Diego, La Jolla, CA, 2Department of Biochemistry and Biophysics, UC San Francisco, San Francisco, CA

B1466/P801 Single-cell analysis of the entrance and exit of cells from log phase growth reveals stochastic cellular decision-making. S. Stylianidou1, J. Cass1, P.A. Wigins1,2,3; 1Physics, University of Washington, Seattle, WA, 2Bioengineering, University of Washington, Seattle, WA, 3 Microbiology, University of Washington, Seattle, WA

Defining Therapeutic Targets and New Therapeutics 1

B1467/P802 Architecture of a lipid transport system for the bacterial outer membrane. G. Bhabha1, G. Greenan1, S. Ovchinnikov2, J.S. Cox1, R.D. Vale1, D.C. Ekiert1; 1University of California, San Francisco, San Francisco, CA, 2University of Washington, Seattle, WA B1468/P803 Evolutionary divergence of CTP synthase polymerization-based regulation. E.M. Lynch1, D. Hicks1, M. Shepherd2, A. Maker1, R. Barry3, Z. Gitai3, E.P. Baldwin4, J.M. Kollman1; 1Department of Biochemistry, University of Washington, Seattle, WA, 2Department of Biology, McGill University, Montreal, QC, 3Department of Molecular Biology, Princeton University, Princeton, NJ, 4Department of Molecular and Cellular Biology, University of California Davis, Davis, CA B1469/P804 Resveratrol leads to oxidative cell damage in Salmonella typhimurium. W. Lee1, D. Lee1; 1School of Life Sciences, Kyungpook National University, Daegu, Korea, South B1470/P805 Clathrin plays an important role in phagolysosome breakdown. R.M. Dayam1; 1Chem & Bio, Ryerson University, Toronto, ON B1471/P806 Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMPGMP (3′, 3′-cGAMP). Z.F. Hallberg1, X.C. Wang2, T.A. Wright1, C.H. Chan3, J. Yeo1, O. Ad1, B. Nan4, D.R. Bond3, M.C. Hammond1,2; 1Chemistry, University of California, Berkeley, Berkeley, CA, 2 Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 3 Microbiology, University of Minnesota, St. Paul, MN, 4Biology, Texas AM, College Station, TX

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1475/P809 Characterization of functional enhancement human mesenchymal stem cells using gene delivery systems. J. Kim1, J. Choi1, H. Lew2, S. Lee3, G. Kim1; 1Department of Biomedical Science, CHA University, Seongnam-si, Korea, South, 2Department of Ophthalmology, CHA Bundang Medical Center CHA University, Seongnam, Korea, South, 3Department of Oral Pathology, College of Dentistry, Kangnung National University, Gangneung Si, Korea, South B1476/P810 A Comparison of Angiotensin Converting Enzyme Inhibitor Therapy on Herpes Simplex Virus Type-1 Infected Cells. A. Wofford1, K. Harris1, S. Thomas1, C. Jackson2, G.D. Griffin3, C.N. Bradford1; 1Biology, Tuskegee University, Tuskegee, AL, 2Biology, Nashville State University, Nashville, TN, 3Biology and Psychology, Hope College, Holland, MI B1477/P811 Development of novel bioconjugate to increase the bioavailability of vitamin A. V. Joga1, S. Rentala2, A. Mokkapati2; 1Dept. of Biotechnology, Institute of Science, GITAM University, Visakhapatnam, India, 2Dept of Biotechnology, Institute of Technology GITAM University, Visakhapatnam, India B1478/P812 Effects of a massaging device, based on an oscillating torque, upon the expression of some dermal proteins of human skin. Influence of frequency. E. Caberlotto1, Z. Miller1, A. Poole1, L. Ruiz1, j. Genisson2, M. Bernal2, M. Tanter2, M. Poletti1, L. Tadlock1; 1L’Oréal, Paris, France, 2 ESPCI, Institut Langevin, Paris, France B1479/P813 Female-Specific Role of Progranulin to Suppress Bone Formation. L. Wang1, T. Roth1, R.A. Nissenson1; 1Endocrine Unit, SF VA Medical Center, San Francisco, CA

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B1456/P792 Using synthetic enhancers to predict gene expression patterns in early Drosophila embryos. A. Reimer1, M. Child VI2, M. Turner1, N. Almeida3, H.G. Garcia2,4; 1Biophysics, UC Berkeley, Berkeley, CA, 2Physics, UC Berkeley, Berkeley, CA, 3Biology, St. Bonaventure University, St. Bonaventure, NY, 4MCB, UC Berkeley, Berkeley, CA

Sunday Poster Session

Board No./Presentation No. B1480/P814 Bone formation in calvarial defects treated with mesenchymal stem cells or osteoblasts derived from adipose tissue: microtomographic analysis. G.P. Freitas1, H.B. Lopes1, A.L. Almeida1, M.M. Beloti1, A.L. Rosa1; 1Cell Culture Laboratory, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil B1481/P815 The interaction between ataxin-3 and Rad23 regulates polyglutamine toxicity in Drosophila models of Spinocerebellar Ataxia Type 3. J.R. Sutton1, J.R. Blount1, S.V. Todi1; 1Pharmacology, Wayne State University School of Medicine, Detroit, MI B1482/P816 Role of microRNA and its target genes in Chronic Kidney Disease Patients as a Diagnostic Tool. M.J. Khan1, A. Khan1, F.G. Noshahi1, A. Naeem1; 1Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Islamabad, Pakistan B1483/P817 Bone formation in calvarial defects of osteoporotic rats implanted with bioactive glass-ceramic associated with mesenchymal stem cells. A.L. Almeida1, A.T. De Souza1, G.P. Freitas1, H.B. Lopes1, M. Crovace2, O. Peitl-Filho2, L.G. Souza3, S. Siessere3, M.M. Beloti1, A.L. Rosa1; 1Cell Culture Laboratory, School of Dentistry of Ribeirão Preto, University of Sao Paulo, RIBEIRAO PRETO, Brazil, 2 Vitreous Materials Laboratory, Department of Materials Engineering, Federal University of São Carlos, SÃO CARLOS, Brazil, 3 Department of Morphology, Physiology and Basic Pathology, School of Dentistry of Ribeirão Preto, University of Sao Paulo, Ribeirao Preto, Brazil B1484/P818 Participation of ERK1/2 in osteoblast and adipocyte differentiation of mesenchymal stem cells induced by distinct titanium surface topographies. H.F. Silva1, R.P. Abuna1, H.B. Lopes1, P.T. OLIVEIRA1, A.L. Rosa1, M.M. Beloti1; 1School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil B1485/P819 Bone Marrow Mesenchymal Stem Cells Accelerate the Restoration of Corneal Antioxidant Protective Mechanisms Decreased After Alkali Burns. C. Cejka1, V. Holan1, P. Trosan1, A. Zajicova1, E. Javorkova1, J. Cejkova1; 1Department of Transplantation Immunology, Czech Academy of Sciences, Institute of Experimental Medicine, Prague 4, Czech Republic

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Sunday Poster Session B1486/P820 TRIM72/CAV1 interaction determines repair influx and fibrogenesis outflux in pulmonary fibrosis. X. Cong1, N. Nagre1, W. Huang2, J. Herrera3, J.M. Schreiber1, M. Clements4, L.L. Wellman4, P.B. Bitterman3, R.D. Hubmayr5, X. Zhao1,2; 1Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA, 2College of Pharmacy, The Ohio State University, Columbus, OH, 3Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Minneapolis, MN, 4Biorepository, Eastern Virginia Medical School, Norfolk, VA, 5 Thoracic Diseases Research Unit, Mayo Clinic, Rochester, MN

B1493/P827 A Multi-Omic Framework for Evaluating the Functional Impact of the Shared Genetic Landscape Across Common Autoimmune Diseases. Y.R. Li1, J. Li1, R. Baldassano1, H. Li2, B.J. Keating3, E.T. Prak4, H. Hakonarson1; 1Genetics, Children’s Hospital of Philadelphia, Philadelphia, PA, 2Biostatistics, University of Pennsylvania, Philadelphia, PA, 3Surgery, University of Pennsylvania, Philadelphia, PA, 4Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

B1487/P821 Combinatory transplantation of BMSCs and EPCs with substance P improve the recovery from stroke by facilitating the pericyte-like coverage of BMSCs and restoring blood brain barrier. M. Zhang1, W. Ahn1, S. Kim1, Y. Son1; 1Department of Genetic Engineering, Kyung Hee University, Yong In, Korea, South B1488/P822 Targeting primary cilia structure enhances intercellular signaling and whole bone adaptation. M. Spasic1, M.P. Duffy1, C.R. Jacobs1; 1Biomedical Engineering, Columbia University, New York, NY B1489/P823 SP treatment at acute phase of the ischemic stroke stimulates BBB reformation, reduces ischemic area, and improves functional recovery, possibly through regulation of M2-skewed monocytes from BM. W. Ahn1, M. Zhang1, G. Chi1, S. Kim1, H. Hong1, J. Lim1, E. Chung1, Y. Son1; 1Department of genetic engineering, KyungHee University, Yonginsi, Korea, South B1490/P824 NCEH-1 modulates cholesterol metabolism and protects against α-synuclein toxicity in a C. elegans model of Parkinson’s disease. S. Zhang1, S. Glukhova1, K.A. Caldwell1, G.A. Caldwell1; 1Biological Sciences, The University of Alabama, Tuscaloosa, AL B1491/P825 Analgesic effects of β-PGG in an LPS-induced pain animal model. K. Chun1, J. Ra2, S. Kim2, M. Ju2, H. Choi2, S. Kim3, S. Hong3, S. Lee2; 1Research and Development Center, Huons Co., Ltd, Ansan, Korea, South, 2Food Science and Biotechnology, Kyungpook Natioinal University, Daegu, Korea, South, 3 Department of Anesthesiology, Kyungpook National University School of Medicine, Daegu, Korea, South B1492/P826 PPAR α, γ agonists and vascular statin enhance reverse cholesterol transport activity in sdLDL(small dense LDL) induced foam cells. M. Mori1, K. Shimizu1, J. kasahara1, K. Imai1, M. Hikosaka1, R. Motohashi1, S. Kikuchi1, M. Takahashi1; 1CellBiological Pathology, Chiba Institute of Science, Choshi, Japan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Monday Poster Session ASCB Learning Center, Exhibit Halls A-C Poster Set Up Sunday 6:00–6:30 pm Posters Displayed Sunday 6:30 pm–8:00 pm Monday 7:30 am–5:30 pm

Author Presentation Odd Boards 12:00–1:30 pm Even Boards 1:30–3:00 pm Poster Tear Down Monday 5:30–6:00 pm

Board Numbers Session Titles

B1041-B1055 Neuronal Protein and Organelle Trafficking B1056-B1066 Neuronal Degeneration and Regeneration B1067-B1089 Mitochondria, Chloroplasts, and Peroxisomes 2 B1100-B1116 Lipids and Membrane Microdomains 2 B1118-B1141 Post-Translational Modifications in Signaling B1142-B1161 Kinases and Phosphatases 1 B1162-B1165; B1200-B1208 Signaling Receptors (RTKs and GPCRs) 1 B1210-B1231 Signaling Networks Governing Cell Migration B1232-B1247 Cytoskeleton-Membrane Interactions B1249-B1270 Cadherins and Cell-Cell Interactions B1271-B1277 Glycoproteins, Invadosomes, and Remodeling B1278-B1286; B1300-B1307 Structure and Function of the Extracellular Matrix B1309-B1325 Chaperones, Protein Folding, and Quality Control 2 B1326-B1337 Ubiquitin and Proteasome Function B1339-B1349 Computational Cell Biology and Bioinformatics B1351-B1370 Embryogenesis 1 B1400-B1427 Signaling in Tissue Development and Morphogenesis B1429-B1450 Cell Biology of Protists and Viruses B1451-B1470 Host-Pathogen/Host-Commensal Interactions 1 B1472-B1485 Cell Signaling in Normal and Diseased Organs B1486-B1492 Digestive and Excretory Organs

2016 ASCB Meeting Poster Presentation Guidelines •

Presenters should ensure their posters are placed on the appropriate poster board for the duration of their assigned poster session and viewing. Please use the number starting with “B” for your poster board.



Poster presenters should stand at their poster locations during the appropriate 90-minute time slot—odd board numbers, 12:00-1:30 pm or even board numbers, 1:30-3:00 pm (specific time slot is included in the original poster notification emails sent on November 2). If presenters have to leave early, they should post a note on their boards with contact information or stating when they will be available to answer attendee questions.



IMPORTANT! Poster presenters are solely responsible for placing and removing their poster according to the schedule provided above. If you are unable to set up your poster the evening before your session, please do so the morning of your presentation.



Poster presenters should not leave any items unattended at their poster board, including poster tubes, meeting bags, Programs, Poster Guides, personal items, etc. The ASCB is not responsible for any items left in the ASCB Learning Center.



Cameras/Photography: Cameras and all other recording devices are strictly prohibited in all session rooms, in the ASCB Learning Center, and in all poster and oral presentation sessions.

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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MONDAY

B200-B225 Science Education 2 B227-B253 New Technologies for Cell Biology 2 B254-B263 New Techniques in Genomics B264-B285 Actin and Actin-Associated Proteins 2 B286-B299 Higher-Order Actin-Based Structures B300-B314 Actin-Membrane Interactions B316-B340 Myosins B342-B366 Microtubule Nucleation and Organization B367-B389 Cilium Structure, Composition, and Motility B400-B418 Spindle Assembly 2 B419-B439 G1, G1-S, S, and G2-M Phase Regulation B440-B454 Kinetochore Assembly and Functions 2 B455-B467 Centrosome Assembly and Functions 2 B468-B489; B500-B508 Cancer Therapy 2 B509-B530 Oncogenes and Tumor Suppressors 2 B531-B548 Migration and Metastasis B549-B568 Tumor Microenvironment 2 B900-B915 Gene Structure and Transcription B916-B932 Post-Transcription Gene Regulation B934-B948 The Nuclear Envelope and Nuclear Pore Complexes 2 B949-B967 Nuclear Bodies and Dynamics B969-B986; B1000-B1007 Endocytic Trafficking 2 B1008-B1024 Endosomes, Lysosomes, and Lysosome- Related Organelles 1 B1025-B1039 Post-Golgi Trafficking

Board No./Presentation No.

Science Education 2 B200/P828  Preparing for the 21st Century Biomedical Research Job Market: Using Census Data to Inform Policy and Career Decision-Making. M.L. Heggeness1, K.T. Gunsalus2,3, J. Pacas1, G.S. McDowell2,4; 1U.S Census Bureau, Washington, DC, 2Future of Research, Abington, MA, 3Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, 4Manylabs, San Francisco, CA B201/P829  Targeted career exploration assignments increased confidence level in next-steps in career path for upper-level Biology majors. L.P. Hammonds-Odie1; 1School of Science and Technology, Georgia Gwinnett College, Lawrenceville, GA B202/P830  The great ideas of biology: Exploration through experimentation in an undergraduate lab course. L. Finch1,2, C.V. Horii3, R. Phillips4, J.S. Bois4; 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 2ATLAS Institute, University of Colorado, Boulder, CO, 3Center for Teaching, Learning, and Outreach, California Institute of Technology, Pasadena, CA, 4Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA B203/P831  Genome Solver: Evidence for Student Learning in Bioinformatics. V. Mathur1, G. Arora2, A. Rosenwald1; 1Biology, Georgetown University, Washington, DC, 2Science, Technology, and Mathematics, Gallaudet University, Washington, DC B204/P832  Developing course-based undergraduate research experiences (CUREs) through long-term mentorship: The ASCB Mentoring in Active Learning and Teaching (MALT) program. M.J. Wolyniak1, A.J. Prunuske2, M.J. Dobro3, S.M. Wick4; 1Biology, Hampden-Sydney, Hampden-Sydney, VA, 2 Microbiology and Molecular Genetics, Medical College of Wisconsin, Wausau, WI, 3Human Biology, Hampshire, Amherst, MA, 4College of Biological Sciences, University of Minnesota, St. Paul, MN B205/P833  Evaluation of pedagogical innovations: a survey of educational research literature in cell biology. O.M. Kielbasa1; 1Biology Program, Department of Science and Mathematics, Alvernia University, Reading, PA B206/P834  Developing a curriculum-wide “Pipeline” CURE that connects PUIs with R1s. T. Lee1, B. Carpenter1, C. May2, D.J. Katz1, K.L. Schmeichel2; 1Cell Biology, Emory University, Atlanta, GA, 2Biology, Oglethorpe University, Atlanta, GA B207/P835  Southern Illinois Bridges to Baccalaureate Program promotes the retention of community college students in 4-year university science programs. J.R. Lucas1, K. Renzaglia1; 1Plant Biology, Southern Illinois University, Carbondale, IL

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Monday Poster Session B208/P836  Urban High School Students’ Exposure to Authentic Scientific Research: Production of a Recombinant Construct for Mechanistic Studies of Collagen IV Assembly. I.A. Ero-Tolliver1; 1Biological Sciences, Hampton University, Hampton, VA B209/P837  Assessment of a semester-long course-based undergraduate research experience examining zebrafish regeneration. A.K. Becker1, P.S. Sickler1, E.A. Jimenez2, S. Walsh1; 1Biology, Rollins College, Winter Park, FL, 2National Human Genome Research Center, National Institutes of Health, Bethesda, MD B210/P838  Evaluating Psychosocial Mechanisms Underlying STEM Persistence in Undergraduates: Evidence of Impact from an Intensive 6-Day Pre-College Engagement Program. R.S. Pollenz1, D. Findley-Van Nostrand1; 1Cell Biology and Office for Undergraduate Research, University of South Florida, Tampa, FL B211/P839  Early impacts on students in two introductory biology course-based undergraduate research experiences (CUREs) at a comprehensive teaching institution. K. McDonald1, A. Martin1, M.A. Johnson1, A.J. Rechs1, T.E. Landerholm1, C.P. Watters1; 1Biological Sciences, California State University, Sacramento, CA B212/P840  Fostering student cognitive engagement in a large-class Biology undergraduate module using a question-generation assignment. F.M. Yeong1, C.F. Chin1, A.L. Tan2; 1Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 2Natural Sciences and Science Education, National Institute of Education, Nanyang Technological University, Singapore, Singapore B213/P841  When lab leads lecture: redesigning introductory biology experience at a small undergraduate university to engage students through open-ended, lab-based inquiry. L.M. Alford1, R.L. Donnelly1, C. Baube1, N. Strong1, K.L. Schmeichel1; 1Biology, Oglethorpe University, Atlanta, GA B214/P842  The Promoting Active Learning and Mentoring (PALM) Research Coordination Network. S.M. Wick1,2, M.J. Wolyniak2,3, M. Peifer2,4, A.J. Prunuske2,5; 1Biology Teaching Learning, University of Minnesota, Minneapolis, MN, 2Education Committee, ASCB, Bethesda, MD, 3Biology, Hampden-Sydney College, Hampden-Sydney, VA, 4Biology, University of North Carolina, Chapel Hill, NC, 5Microbiology and Molecular Genetics, Medical College of Wisconsin, Wausau, WI B215/P843  Sustaining an active research program through classroom undergraduate research experiences. L.F. Barton1; 1Biology Department, Austin College, Sherman, TX B216/P844  Freshman participation in a course-based research experience increases science identity, science self-efficacy, and science value. D.C. Tucker1, J.L. March1, A.K. Challa2, G. Jones3; 1Science and Technology Honors Program, University of Alabama at Birmingham, Birmingham, AL, 2Genetics, Genomics, and Bioinformatics, University of Alabama at Birmingham, Birmingham, AL, 3Office of Undergraduate Research, University of Alabama at Birmingham, Birmingham, AL

B217/P845  Assessing the efficacy of active learning as a means of improving critical thinking in STEM education. M.L. Styers1, P.A. Van Zandt1, K.L. Hayden2; 1Department of Biology, Birmingham-Southern College, Birmingham, AL, 2Department of Chemistry and Physics, Birmingham-Southern College, Birmingham, AL B218/P846  MAMS – A cell biology rich bridge program to health professional school. M.A. Taylor1,2; 1Biomedical Sciences, Pacific Northwest University of Health Sciences, Yakima, WA, 2Science, Heritage University, Toppenish, WA B219/P847  Seeing Scientifically: scaffolding scientific observation in a museum setting. J. Ma1, E. Shahar1, B. Dai2, G. Mehta2, K. Eliceiri2, K.R. Yu1; 1Exploratorium, San Francisco, CA, 2Laboratory for Optical and Computational Instrumentation, University of Wisconsin, Madison, Madison, WI B220/P848  Faculty positions in the life sciences: Improving trainees’ awareness of hiring criteria. J.B. Dorman1, T.A. Nguyen1, N. Saul1, R. McGee2, A.C. Goldfien3, L. Clement1; 1Office of Career and Professional Development, University of California, San Francisco, San Francisco, CA, 2Feinberg School of Medicine, Northwestern University, Chicago, IL, 3 Graduate College of Education, San Francisco State University, San Francisco, CA B221/P849  Effects of hierarchical peer mentoring within a biology first-year experience course on freshmen retention. P.J. Cavnar1, C. Stanny2; 1Biology, University of West Florida, Pensacola, FL, 2Center for University Teaching, Learning, and Assessment (CUTLA), University of West Florida, Pensacola, FL B222/P850  Incorporating community-engaged learning into a summer undergraduate research program: a full CIRCLE approach to undergraduate training. A.F. ODonnell1, S.K. Woodley1; 1Dept. of Biological Sciences, Duquesne University, Pittsburgh, PA B223/P851  The PULSE Ambassador Program Effectively Promotes Curricular Reform in Life Science Departments. C.G. Reiness1, N.P. Jacob2, M.I. Kelrick3; 1Biology, Lewis & Clark College, Portland, OR, 2Biology, Oxford College of Emory University, Oxford, GA, 3Biology, Truman State University, Kirksville, MO B224/P852  Pre-Freshman Summer Immersion Programs to Increase Minority Retention in STEM disciplines: Two Different Strategies. C. Selassie1, D. Drew2, C.M. Cheney3, D. Graves4, M. Preest5; 1Chemistry, Pomona College, Claremont, CA, 2School of Education, Claremont Graduate University, Claremont, CA, 3Biology, Pomona College, Claremont, CA, 4President’s Office, Claremont McKenna College, Claremont, CA, 5Keck Science Department, Claremont McKenna, Scripps and Pitzer Colleges, Claremont, CA B225/P853  S-STEM Scholarship Program at UNC Pembroke: a COMPASS for Science Majors. M.S. Santisteban1, R. Bullard-Dillard2, J.E. Thomley3; 1Biology, University of North Carolina at Pembroke, Pembroke, NC, 2Chemistry and Physics, University of North Carolina at Pembroke, Pembroke, NC, 3Mathematical Sciences, Appalachian State University, Boone, NC

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

New Technologies for Cell Biology 2 B227/P854  Targeting telomerase for cell therapy. S. LI1; 1Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore B228/P855  Targeted protein degradation with synthetic E3 ubiquitin ligase complexes. Y. Kee1, K. Kim1, B.J. Hwang2; 1Division of Biomedical Convergence, Kangwon National University, Chuncheon, Korea, South, 2Department of Molecular Bioscience, Kangwon National University, Chuncheon, Korea, South B229/P856  HPLC (High performance liquid chromatography) analysis from the secretory fluids of maxillary sinusitis and maxillary retention cyst. S. Kim1, M. Eo1, Y. Cho1, Y. Kim2, S. Lee3; 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Dental Research Institute, Seoul National University, Seoul, Korea, 2Department of Dental Hygiene, Cheongju University, Cheongju, Korea, 3Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea

B231/P858  Analysis of breast and colon tumors using a novel Milliplex Protein Translation multiplex immunoassay. J. Hwang1, M. Schluter1, D. Pepin1, Q. Xiao1; 1RD, MilliporeSigma, St. Louise, MO B232/P859  Project Discovery – Bringing real science to mainstream gaming creates an enthusiastic and fast resource for scientific research. D.P. Sullivan1, M. Wiking1, L. Åkesson1, R. Schutten1, M. Hjelmare1, E. Lundberg1; 1Proteomics and Nanobiotechnology, Science for Life Laboratory (KTH), Stockholm, Sweden B233/P860  Programmed cell fate changes in mammalian cells using CRISPR-based synthetic transcription factors. M.F. La Russa1,2, M. Torres2, Y. Liu2, Y. Gao3, L.S. Qi2; 1Biomedical Sciences, University of California, San Francisco, San Francisco, CA, 2Bioengineering, Stanford University, Stanford, CA, 3Cancer Biology, Stanford University, Stanford, CA B234/P861  Systematic gene tagging to illuminate stem cell organization. R. Gunawardane1; 1Allen Institute for Cell Science, Seattle, WA B235/P862  Use of CRISPR to Engineer Stem Cell Lines For Improved Homogeneous Differentiation. R. Thompson1, C. Chan2; 1Biomolecular Sciences, Michigan State University, East Lansing, MI, 2Chemical Engineering, Michigan State University, East Lansing, MI B236/P863  Tagging Endogenous TERT protein through CRISPR-Cas9-mediated Genome Editing Enables Tracking Telomerase in Living Cancer Cells. L. Xi1,2, J. Schmidt1, A. Zaug1, T. Cech1, E. Fuchs2; 1Biofrontiers Institute, University of Colorado Boulder, Boulder, CO, 2Rockefeller University, New York, NY

B237/P864  Development and Optimization of a High Titer Recombinant Lentivirus Production System. A.S. Storck1, J.J. Ludtke1, N.A. Rossi1, L.K. Juckem1; 1RD, Mirus Bio LLC, Madison, WI B238/P865  Efficient mRNA Delivery in difficult-to-transfect cells with jetMESSENGER™ Transfection Reagent. V. MoreauToussaint1, T. Benchimol1, J. Havard1, G. Guerin-Peyrou1, F. Premartin1, M.P. Dumont1, A.M. Nyamay’Antu1, G. Freund1, C. Marion1, C. Croizier1, F. Stock1, P. Erbacher1; 1RD, Polyplus-transfection, Strasbourg, France B239/P866  Efficient selection of antibody fragments using phage display and exhaustive yeast two-hybrid screening. P. Tafelmeyer1, S. Moutel2, S. Djander1,2, V. Collura1, A. Arrial1, A. Olichon3, F. Perez4, J. Rain1; 1Hybrigenics Services SAS, Paris, France, 2Translational Research Department, Institut Curie, Paris, France, 3CRCT, INSERM, Toulouse, France, 4CNRS UMR144, Institut Curie, Paris, France B240/P867  Tuning the stem cell microenvironment: oxygen and pressure are key players in iPSC generation and differentiation. Z. Pappalardo1, L. Cassereau2, B. Adams2, B. Downey2, B. Feth2, J. Lim2; 1Biology, San Francisco State University, San Francisco, CA, 2RD, Xcell Biosciences, San Francisco, CA B241/P868  Phenotypic characterization of CRISPR/Cas9 edited cell lines using High throughput, quantitative fluorescence microscopy. N.J. Dolman1, K. Chambers1, B. Samson1, M.S. Janes1; 1Biosciences, Thermo Fisher Scientific, Pittsburgh, PA B242/P869  Use of blastocysts to determine the effectiveness of different sgRNAs and donor DNAs for genomic editing by CRISPR/Cas9 prior to use in mice. E. McBeath1, J. Parker-Thornburg2, C. Smith2, J. Abe1, K. Fujiwara1; 1Cardiology, University of Texas MD Anderson Cancer Center, Houston, TX, 2Genetics, University of Texas MD Anderson Cancer Center, Houston, TX B243/P870  Attempt to develop a CRISPR system for use in Dictyostelium discoideum. M. Al-hejjaj1,2, D. Watts1, E.H. Hettema1; 1Molecular Biology and Biotechnology, The University of Sheffield, Sheffield, United Kingdom, 2Microbiology, The University of Basrah, Albasrah, Iraq B244/P871  Footprint-free gene editing using CRISPR/Cas9 and single-cell cloning of edited human iPS cells. M. Morell1, T. Garachtchenko1, H. Matsumoto1, M. Haugwitz1, A. Farmer1; 1Takara Bio USA, Inc., Mountain View, CA B245/P872  Machine learning-enabled analytical tool for kinetic drug screening of induced motor neuron survival in ALS patient panels. T. Cheng1, G.R. Linares2, H. Sasaki1, . Lai1, W. Donaldson1, C. Huang1, J. Ichida2, S.J. Lee1; 1DRVision Technologies LLC, Bellevue, WA, 2Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B246/P873  Inference of survival states in induced motor neurons of neurological diseases. H. Sasaki1, T. Cheng1, M. Jones1, Y. Li2, H. Lai1, C. Huang1, J. Ichida2, S.J. Lee1; 1DRVision Technologies LLC, Bellevue, WA, 2Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA B247/P874  In vitro analysis of super-active TALE protein. K. Ikeda1, Y. Terahara1, N. Miyashita2, Y. Okada1; 1Quantitative Biology Center, RIKEN, Osaka, Japan, 2Faculty of Biology-oriented Science and Technology, KINDAI University, Wakayama, Japan B248/P875  Magnetic-microcontact printing based ECM nano-patterning allows homogeneous controlling of cell growth and behavior. M. Schneider1, J. Foncy2, A. Lagraulet3, B. Berteloite3, A. Esteve2, M. Blatche4, L. Malaquin2, C. Vieu2,5; 1Innopsys Inc, Chicago, IL, 2LAAS, Biosoft-CNRS, Toulouse, France, 3 Innopsys SA, Carbonne, France, 4LAAS, CNRS, Toulouse, France, 5LAAS, Université de Toulouse-INSA, Toulouse, France B249/P876  The effect of maltose on the longterm storage of laminin-pre-coated vessels for iPS cell cultures. E. Matsumoto1, K. Suto2, H. Hanzawa1, K. Kobayashi2, S. Takeda1; 1Research Development Group, Hitachi, Ltd., Hatoyama, Japan, 2New Business Development Headquarters, Hitachi Chemical Co., Ltd., Tokyo, Japan B250/P877  Universal extracellular matrix supports toxicology and drug screening in 2D and 3D cell culture models from iPSC derived cells, primary cells, engineered lines and cancer lines. J. Clinton1, P. McWilliamsKoeppen1, L.M. Panicker1, D. Yin1; 1ATCC Cell Systems, American Type Culture Collection (ATCC), Gaithersburg, MD B251/P878  A novel treatment for the prevention of diet-induced cardiovascular disease and metabolic syndrome. H. Mirzaei1; 1Gerontology, USC, Los Angeles, CA B252/P879  In vitro culture of cells up to 15and 49-days postmortem in bovine skin stored at 25°C and 4°C, respectively. M. Singh1, B. Walcott1; 1Animal Science, Fort Valley State University, Fort Valley, GA B253/P880  Characterization of Novel Cell Lines for Studying Age-Related Onset of Huntington’s Disease. C. Hung1, T. Maiuri1, V. Mattis2, R. Truant1; 1Biochemistry, McMaster University, Hamilton, ON, 2Regenerative Medicine, Cedars Sinai Medical Institute, Los Angeles, CA

New Techniques in Genomics B254/P881  CRISPulator: a discrete simulation tool for designing pooled genetic screens. T. Nagy1, M. Kampmann2,3; 1Integrative Program in Quantitative Biology, University of California, San Francisco, San Francisco, CA, 2Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, 3Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B255/P882  Integration deficient lentivirus is a safe and effective gene delivery system for gene editing. J. Lin1, X. Sun1, L. Min1, Y. Wang1; 1OriGene Technologies, Inc., Rockville, MD

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MONDAY

B230/P857  Single molecule pathway monitoring of the Argonaute RISC formation process. T. Komori1, R. Murakami1, M. Moriya1, K.M. Nishida1, M.C. Siomi1, S. Uemura1; 1Grad. School of Science, Univi, of Tokyo, Tokyo, Japan

Monday Poster Session

Board No./Presentation No. B256/P883  Peptide based non-viral delivery of CRISPR-Cas9 for efficient genome engineering in mammalian cells. G. Divita1, N. Desai1; 1Aadigen LLC, Pacific Palisades, CA B257/P884  Highly efficient delivery of potent nucleic acids for modulating gene expression in vitro and in vivo using optimized lipid nanoparticles. T. Yamagami1, E. Ouellet1, R. DeSouza1, G. Tharmarajah1, O. Seira2, J. Liu2, A. Thomas1, T. Leaver1, A. Wild1, W. Tetzlaff2,3, P. Deng4, D.J. Segal5, J. Nolta4, K.D. Fink4, J. Taylor1, E. Ramsay1; 1Precision NanoSystems Inc., Vancouver, BC, 2International Collaboration on Repair Discoveries (ICORD), Vancouver, BC, 3Zoology, University of British Columbia, Vancouver, BC, 4Stem Cell Program and Institute for Regenerative Cures, University of California Davis Health Systems, Sacramento, CA, 5Genome Center, MIND Institute, and Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA B258/P885  Genome-scale knockout screening strategy in ancient metazoan cells. R. Viswanatha1, Y. Hu1, B.E. Housden1, N. Perrimon1; 1Genetics, Harvard Medical School, Boston, MA B259/P886  Cell-penetrating antisense GapmeR for functional gene silencing in human primary T-lymphocytes. F. M H U Turabe1, J. Low1, A. Kizakeyil1, S. Ong1, M.L. Chalasani1, D. Kelleher2, N.K. Verma1,3; 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore, 2University of British Columbia, Vancouver, Canada, 3 Singapore Eye Research institute, Singapore, Singapore B260/P887  Elucidating Cellular Trafficking Pathways Controlling Prion-like Spread of Tau Aggregation Using CRISPR interference Screens. D.L. Nathaniel1, J. Chen1, S. Mok1, J. Gestwicki1, M. Kampmann1; 1Institute for Neurodegenerative Disease, UCSF, San Francisco, CA B261/P888  Reconstruction of a Genetic Pathway Using Transcriptome Mapping in a Metazoan. D. Angeles-Albores1, C.P. Robinson1, B. Williams1, I. Antoshechkin1, P.W. Sternberg1; 1Biology and Biological Engineering, Caltech, Pasadena, CA B262/P889  Validation of reference genes to study osteoblastic cells using qPCR. R.P. Flores Abuna1, H.B. Lopes1, F.S. Oliveira1, G.P. Freitas2, J.I. Reis Ramos1, M.M. Beloti1, A.L. Rosa2; 1Morphology, Physiology and Basic Pathology, University of Sao Paulo, Ribeirao Preto, Brazil, 2Oral Maxilo Facial Surgery and Periodontics, University of Sao Paulo, Ribeirao Preto, Brazil B263/P890  A scalable high-throughput method for RNA-Seq analysis of thousands of single cells. L. Watson1, K. Taylor1, L. Frenz2, D. Greiner2, R. Lebofsky2, D. Do2, P. Priyadarshini2, P. Chen2, B. Zhang2, M. Ma2, P. Pattamatta2, L. Javier2, J. Mopas2, J. Chew2, S. Cater2, E. Wong-Ho2, F. Schlesinger1, I. Khrebukova1, J. Patel1, C. Lin1, J. Tsai1, V. Montel1, M. Kellogg1, A. Hartnett1, A. Yunghans1, J. Agresti2, G.P. Schroth1; 1Illumina, Inc, San Diego, CA, 2Digital Biology Center, Bio-Rad Laboratories, Inc, Pleasanton, CA

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Monday Poster Session

Actin and Actin-Associated Proteins 2 B264/P891  Characterizing the processive mechanism of Ena/VASP on diverse F-actin bundles. A.J. Harker1, J.D. Winkelman2, C.A. Anderson2, D.R. Kovar1,2; 1Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, 2Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL B265/P892  The E3 Ubiquitin Ligase TRIM67 Regulates Cytoskeletal Response to Netrin-1. N. Boyer1, S. Menon1, S.L. Gupton1; 1Cell Biology & Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC B266/P893  Monoubiquitination inhibits the actin bundling activity of fascin. S. Lin1, S. Lu2, J. Sun2, T. Keeley1, S. Yang1; 1Cellular and Molecular Physiology, Penn State University College of Medicine, Hershey, PA, 2Tumor Biology, H. Lee Moffitt Cancer Center, Tampa, FL B267/P894  Fascin crosslinks turnover much faster than actin filaments in stereocilia. P. Roy1, B.J. Perrin1; 1Biology, Indiana UniversityPurdue University Indianapolis, Indianapolis, IN B268/P895  Competitive and cooperative interactions between actin binding proteins drive their sorting to different actin cytoskeleton networks. J.R. Christensen1, K.E. Homa1, M.E. OConnell1, A.N. Morganthaler1, D.R. Kovar1; 1Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL B269/P896  Elucidating a Mechanism of Calcium-Regulated F-actin Bundling by Human Plastins. C. Schwebach1,2, E. Kudryashova1, D.S. Kudryashov1,2; 1Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, 2Molecular, Cellular, and Developmental Biology Program, The Ohio State University, Columbus, OH B270/P897  TNF-α- dependent signaling mechanisms is required for L-Plastin- mediated actin bundling process at the early phase of sealing ring formation and bone resorption. S. Majumdar1, M.A. Chellaiah1; 1Dental School, University of Maryland, Baltimore, MD B271/P898  L-Plastin, an actin bundling protein, regulates bundling and stability of actin filaments preceding to sealing ring formation in bone resorbing osteoclasts. M.A. Chellaiah1, T. Ma1, C. Morley2, S. Majumdar1; 1Dental School, University of Maryland, Baltimore, MD, 2Pediatric Research, Washington University School of Medicine, St.Louis, MO B272/P899  ADP-ribosylation factors-like 4C Binding to Filamin-A Modulates Filopodium Formation and Cell Migration by Promoting Cdc42 Activation. T.S. Chiang1, H.F. Wu2, F.J. Lee1,2; 1Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan, 2Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan B273/P900  Profilin occupies a critical node in actin/MKL/SRF signaling circuit. M.E. Joy1, D. Gau1, N. Castellucci1, P. Roy1,2,3; 1Bioengineering, University of Pittsburgh, Pittsburgh, PA, 2Cell Biology, University of Pittsburgh, Pittsburgh, PA, 3Pathology, University of Pittsburgh, Pittsburgh, PA

B274/P901  Mutational analysis of conserved hydrophobic residues in the C-terminal actin-monomer binding region of cyclaseassociated protein. S. Iwase1, S. Ono1,2; 1Pathology, Emory University, Atlanta, GA, 2Cell Biology, Emory University, Atlanta, GA B275/P902  Cofilin modifies the actin cytoskeleton in response to thermal stress during morphogenesis. L. Zheng1, L.R. Figard1, A.M. Sokac1; 1Biochemistry, Baylor College of Medicine, Houston, TX B276/P903  Simultaneous Quantification of Actin Monomer and Filament Dynamics with Modelling Assisted Analysis of Photoactivation. M. Kapustina1, E.A. Vitriol2; 1Cell Biology Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Anatomy Cell Biology, University of Florida, Gainesville, FL B277/P904  Effects of Tropomyosin isoforms on actin filament disassembly and remodeling by Coronin, Cofilin, AIP1, and GMF. S. Jansen1, S. Guo1, B.L. Goode1; 1Biology, Brandeis University, Waltham, MA B278/P905  Human cells contain enough tropomyosin to saturate all actin filaments. J. Meiring1, N.S. Bryce1, E.C. Hardeman1, P.W. Gunning1; 1School of Medical Sciences, University of NSW, Sydney, Australia B279/P906  Metabolic impact of targeting the tropomyosin/actin cytoskeleton to treat cancer. E.C. Hardeman1, A.J. Kee1, C.A. Lucas1, J. Chagan1, P.W. Gunning1; 1School of Medical Sciences, UNSW Australia, Sydney NSW, Australia B280/P907  Modeling approaches for studying cooperative binding of tropomyosin to actin filaments. G.M. Hocky1, J.R. Christensen2, D.R. Kovar2,3, G.A. Voth1; 1Department of Chemistry, James Franck Institute, Institute for Biophysical Dynamics, and Computation Institute, University of Chicago, Chicago, IL, 2 Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 3 Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL B281/P908  F-actin bundling by the C’ domain of the Formin Cdc12 is important for contractile ring formation. A.H. Willet1, C.E. Snider1, K.A. Bohnert2, D.R. Kovar3,4, K.L. Gould1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2 Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 3Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 4 Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL B282/P909  Role of metavinculin in actin reorganization and force transmission. H.T. Lee1, L.Y. Kim2, M. Sarker1, M. Lu1, G.M. Alushin2, K. Burridge3, S.L. Campbell1; 1Biophysics and Biochemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Cell Biology and Physiology Center, NIH/NHLBI, Bethesda, MD, 3Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC B283/P910  The role of DRR on cofilin and its resulting effect on the cytoskeleton and invasiveness in GBM. N. Lai1, P. Le1, G. Trinh1, K. Petrecca1; 1Neurology and Neurosurgery, McGill University, Montreal, QC

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B284/P911  A biological role for the evolutionarily conserved Twinfilin-Capping Protein interaction. D. Hilton1, A. Johnston1, A. Simone1, B. Goode1; 1Molecular and Cellular Biology, Brandeis University, Waltham, MA B285/P912  Role of CARMILs during Zebrafish Development. B.C. Stark1, J.A. Cooper1; 1Biochemistry and Molecular Biophysics, Washington University, St Louis, MO

Higher-Order Actin-Based Structures B286/P913  Stability on the edge: Probing the physical mechanisms of polarity maintenance in motile cells. R.M. Garner1, E.F. Koslover2, J.A. Theriot3,4,5; 1Biophysics Program, Stanford University, Stanford, CA, 2Department of Physics, University of California, San Diego, San Diego, CA, 3Department of Microbiology and Immunology, Stanford University, Stanford, CA, 4Department of Biochemistry, Stanford University, Stanford, CA, 5Howard Hughes Medical Institute, Howard Hughes Medical Institute, Chevy Chase, MD

B288/P915  Mechanistic insights into actinseptin filament interactions. M. Mavrakis1, J. Alvarado2, F. Tsai2, A. Bertin3, A. Szuba2, L. Ramond1, G.H. Koenderink2; 1Institut Fresnel, CNRS UMR 7249, Marseille, France, 2FOM Institute AMOLF, Amsterdam, Netherlands, 3 Institut Curie, CNRS UMR 168, Paris, France B289/P916  Cortical Actin Remodelling for Effective Lytic Synapse Formation. M. Saeed1, A. Gil-krzewska2, A. Oszmiana1, A.F. Carisey3, E.M. Mace3, J.S. Orange3, K. Krzewski2, D.M. Davis1; 1Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, United Kingdom, 2 Receptor Cell Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 3Center for Human Immunobiology, Baylor College of Medicine and Texas Children’s Hospital, Houston, TX B290/P917  FMN2 is a melanoma metastasispromoter that mediates formation of a perinuclear actin/adhesion system to protect nuclei and DNA from damage during confined cell migration. C.T. Skau1, R.S. Fischer1, P.S. Gurel1, H.R. Thiam1,2, A. Tubbs3, M.A. Baird1,4, M.W. Davidson4, M. Piel2, G.M. Alushin1, A. Nussenzweig3, P.S. Steeg5, C.M. Waterman1; 1Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 2 UMR 144 Institut Curie/CNRS, Institut Curie, Paris, France, 3Laboratory of Genome Integrity, National Cancer Institute, National Institutes of Health, Bethesda, MD, 4Magnet Lab, Florida State University, Tallahassee, FL, 5Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD

B291/P918  Cytoskeleton self-organization in epithelial cells. S. Jalal1, Y. Tee1, V. Viasnoff1,2,3, A.D. Bershadsky1,4; 1Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 2Department of Biological Sciences, National University of Singapore, Singapore, Singapore, 3Centre National de la Recherche Scientifique, Singapore, Singapore, 4 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel B292/P919  Filament Rigidity and Connectivity Tune the Deformation Modes of Active Biopolymer Networks. S. Stam1,2, S. Banerjee3, K. Weirich3, S. Freedman4, A. Dinner3,5, M.L. Gardel2,3,4; 1Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, 2Biophysical Sciences Program, University of Chicago, Chicago, IL, 3James Franck Institute, University of Chicago, Chicago, IL, 4Physics Department, University of Chicago, Chicago, IL, 5Chemistry Department, University of Chicago, Chicago, IL B293/P920  Uncovering epidermal actin cytoskeleton dynamics in developing C. elegans larvae. S.S. Katz1, A.R. Frand1; 1Biological Chemistry, University of California Los Angeles, Los Angeles, CA B294/P921  The Function of Dynamin 2 in Podosome-regulated Postsynaptic Neuromuscular Junction Maturation. S. Lin1, Y. Liu1; 1Institute of Molecular Medicine, National Taiwan University, Taipei, Taiwan B295/P922  Direct measurement of tension and structural contributions of actomyosin stress fiber subpopulations during cell migration. S. Lee1,2, S. Kumar1,2,3; 1 Joint Graduate Program in Bioengineering, UC Berkeley-UCSF, Berkeley, CA, 2Bioengineering, UC Berkeley, Berkeley, CA, 3Chemical and Biomolecular Engineering, UC Berkeley, Berkeley, CA B296/P923  Mathematical model describing the competition between actin patches and actin cables in fission yeast. C. Langouras1, D. Vavylonis1; 1Physics, Lehigh University, Bethlehem, PA B297/P924  Caspase-mediated cleavage of MRCKα determines contraction of the apical acto-myosin ring and epithelial cell extrusion. P.A. Gagliardi1, D. Somale1,2, A. Puliafito1, G. Chiaverina1,2, L. di Blasio1, M. Oneto3, P. Bianchini3, F. Bussolino1,2, L. Primo1,2; 1Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy, 2 Dept of Oncology, University of Torino, Torino, Italy, 3Nanoscopy, Italian Institute of Technology, Genoa, Italy B298/P925  UNC-45a is critical for the assembly of bipolar myosin II filaments in migrating cells. J. Lehtimaki1, A. Fenix2, T. Kotila1, G. Balistreri1, D. Burnette2, P. Lappalainen1; 1Institute of Biotechnology, University of Helsinki, Helsinki, Finland, 2Cell and Developmental Biology, Vanderbilt University, Nashville, TN B299/P926  Regulation of actin based protrusions by the hedgehog pathway. M.T. Anderson1, N.F. Berbari1, B.J. Perrin1; 1Biology, Indiana University-Purdue University Indianapolis, Indianapolis, IN

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Actin-Membrane Interactions B300/P927  A RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbing. K. Aoki1, J. Ikenouchi1; 1Department of Biology, Kyushu University, Fukuoka, Japan B301/P928  Axonal Haptotaxis Mediated by Grip and Slip between Cell Adhesion Molecule and Adhesive Substrates. N. Inagaki1, K. Abe1, H. Katsuno1, K. Baba1, R. Watanabe2; 1Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Japan, 2Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Japan B302/P929  Nano-clustering of ligands on synthetic APCs influences T-cell membrane and actin organization. E. Benard1, P. Dillard1,2, F. Pi1,3, L. Limozin2, K. Sengupta1; 1STNO, CINaM, Marseille, France, 2LAI, Marseille, France, 3 current address: School of food science of Jiangnan University, Jiangsu, China B303/P930  Activated Integrin receptors directs the generation of functional nanodomains at the plasma membrane of living cells. J. Kalappurakkal1, A.A. Anilkumar1, S. Mayor1,2; 1Cellular Organization and Signaling Group, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India, 2Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India B304/P931  Quantitative analysis of actomyosin-driven movement of membrane-bound phospho-LAT microclusters. A.R. Vega1, J.A. Ditlev1,2, D.V. Koester3, X. Su4, R.D. Vale4, S. Mayor3, M.K. Rosen1,2, K. Jaqaman1; 1Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 2Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 3National Centre for Biological Sciences, Tata Institute for Fundamental Research, Bangalore, India, 4Molecular and Cellular Biology and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA B305/P932  Actin ultrastructural organization during membrane scission events of clathrin-mediated endocytosis resolved by superresolution microscopy. C. Kaplan1, S.J. Kenny2, K. Xu2, D.G. Drubin1; 1Department of Molecular and Cell Biology, UC Berkeley, Berkeley, CA, 2Department of Chemistry, UC Berkeley, Berkeley, CA B306/P933  Arp 2/3-dependent spatial organization of the B cell receptor (BCR) impacts immune synapse formation, BCR signaling output, and B cell activation. M. BolgerMunro1, K. Choi1, J. Scurll2, L. Abraham 1,2, M. Dang-Lawson 1, L. Yeo1, D. Sheen1, H. Lu1, D. Coombs2, M.R. Gold1; 1Microbiology and Immunology, University of British Columbia, Vancouver, BC, 2Mathematics, University of British Columbia, Vancouver, BC B307/P934  Lamellipodia-like membrane protrusions in Giardia lamblia. W. Hardin1, R. Li1, A. Shelton1, A.R. Paredez1; 1Biology, University of Washington, Seattle, WA B308/P935  Interactions of disease-associated WHAMM variants with actin, microtubules, and membranes. A.J. Mathiowetz1, K.G. Campellone1; 1Molecular and Cell Biology, University of Connecticut, Storrs, CT

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MONDAY

B287/P914  Filamin actin-binding and dimerization domain fulfill distinct functions in Z-disc cohesion. N. González-Morales1, F. Schöck1; 1Department of Biology, McGill University, Montreal, QC

Monday Poster Session

Board No./Presentation No. B309/P936  Syndapin functions in orchestrated remodelling of the membrane and actin cytoskeleton. A. Sherlekar1, P. Richa1, R. Rikhy1; 1Biology, Indian Institute of Science Education and Research, Pune, Pune, India B310/P937  Active sorting of nanoscale clusters of GPI-anchored proteins by dynamic cortical actin activity creates membrane domains with liquid-order like properties. S. Saha1, A. Das2, A.A. Anilkumar1, J.K. Mathew1, M. Rao2, S. Mayor1,3; 1Cell Organization and Signalling, National Centre for Biological Science, Bangalore, India, 2Simons Centre for Living Systems, National Centre for Biological Science, Bangalore, India, 3Institute for Stem Cell Research and Regenerative Medicine, Bangalore, India B311/P938  Synaptic, planar polarity and ECM proteins are required for cytonememediated paracrine signaling. H. Huang1, T. Kornberg1; 1Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA

Monday Poster Session B318/P944  Beyond the myosin mesa: a potential unifying hypothesis on the underlying molecular basis of hyper-contractility caused by a majority of hypertrophic cardiomyopathy mutations. D.V. Trivedi*1, S. Nag*1, S.S. Sarkar1, S. Sutton1, K.M. Ruppel1,2, J.A. Spudich1,2; 1Biochemistry, Stanford University, Stanford, CA, 2Cardiovascular Institute, Stanford University, Stanford, CA B319/P945  A role for non-muscle myosin 2B in congenital heart disease: Identifying genetic variants in Pentalogy of Cantrell using whole exome sequencing. B. MacTaggart1, C. Bowen1, J.X. Chong2, M.J. Bamshad2, X. Ma1, R.S. Adelstein1; 1NHLBI, Bethesda, MD, 2 University of Washington Center for Mendelian Genomics, Seattle, WA B320/P946  Activation of nuclear myosin VI leads to enhanced gene expression. N. Fili1, A. dos Santos1, Y. Hari-Gupta1, C.P. Toseland1; 1School of Biosciences, University of Kent, Canterbury, United Kingdom

B312/P939  Bridging spatial and temporal scales to investigate the interplay of membrane components and their juxtaposed cytosolic companions. T.S. van Zanten1, J.K. Mathew1, M. Jasnin2, W. Baumeister2, S. Mayor1; 1National Centre for Biological Sciences (TIFR), Bangalore, India, 2Max Planck Institute of Biochemistry, Martinsried, Germany

B321/P947  Identification of Miro as a mitochondrial receptor for myosin XIX. S. Oeding1, X. Hu1, A. Freitag1, U. Honnert1, P. Nikolaus1, V. Schwarz1, A. Henkel1, K. Majstrowicz1, M. Schelhaas2, M. Baehler1; 1Institute of Cell Biology, Westfalian Wilhelms University, Muenster, Germany, 2Cell Biology of Virus Infection Unit, Westfalian Wilhelms University, Muenster, Germany

B313/P940  How is apical constriction triggered? A possible role for afadin. M.M. Slabodnick1, S. Tintori1, B. Goldstein1; 1Biology, University of North Carolina, Chapel Hill, Chapel Hill, NC

B322/P948  Identification of the myosin superfamily and contractile tissues in sponges. E. Chang1, M.S. Hill1, O.A. Quintero1; 1Department of Biology, University of Richmond, Richmond, VA

B314/P941  Dap160 and Nwk target WASpdependent actin polymerization to the membrane. C.F. Kelley1, E.M. Messelaar1, A.A. Rodal1; 1Biology, Brandeis University, Waltham, MA

B323/P949  The Role of Nonmuscle Myosin II in Vascular Formation. X. Ma1, Y. Uchida1, Y. Mukoyama1, R.S. Adelstein1; 1Genetics & Developmental Biology Center, NHLBI/NIH, Bethesda, MD

Myosins B316/P942  Biophysical properties of human β-cardiac myosin with converter mutations that cause hypertrophic cardiomyopathy. M. Kawana1,2, S.S. Sarkar1, S.C. Sutton1, K.M. Ruppel1,3, J.A. Spudich1; 1Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, 2Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, 3Department of Pediatrics (Cardiology), Stanford University School of Medicine, Stanford, CA B317/P943  Early onset HCM mutations H251N and D239N significantly increase the fundamental biomechanical parameters of human β-cardiac myosin. A.S. Adhikari1,2, K.B. Kooiker2,3, C. Liu1, S.S. Sarkar1, D. Bernstein2,3, J.A. Spudich1,2, K.M. Ruppel1,2,3; 1Biochemistry, Stanford University School of Medicine, Stanford, CA, 2Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, 3 Pediatric (Cardiology), Stanford University School of Medicine, Stanford, CA

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B324/P950  Cellular and Organismal Function of Myosin-X. E.G. Heimsath, Jr.1, Y. Yim2, M. Mustapha3, J.A. Hammer2, R.E. Cheney1; 1Cell Biology Physiology, UNC School of Medicine, Chapel Hill, NC, 2National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 3Department of Otolaryngology - Head Neck Surgery, Stanford University, Stanford, CA B325/P951  Characterization of MYO19 knockdown phenotypes in cultured neurons. A. Li1, B.M. Fujita1, O.A. Quintero1; 1Department of Biology, University of Richmond, Richmond, VA B326/P952  Local pulsatile contractions are an intrinsic property of the myosin 2A motor in the cortex of adherent cells. M.A. Baird1, N. Billington1, A. Wang 1,2, R.S. Adelstein1, J.R. Sellers1, R.S. Fischer1, C.M. Waterman1; 1NHLBI, National Institutes of Health, Bethesda, MD, 2 College Veterinary Medicine, Hunan Agricultural University, Changsha, China

B327/P953  Myosin II filaments in the actin cytoskeleton: distribution, turnover, and long range self-organization. S. Hu1, K. Dasbiswas2, Z. Guo1, Y. Tee1, V. Thiagarajan1, P. Hersen1,3, T. Chew4, S. Safran2, R. Zaidel-Bar1, A.D. Bershadsky1,5; 1Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 2Department of Materials and Interfaces, Weizmann Institute of Science, Rehovot, Israel, 3Laboratoire Matire et Systèmes Complexes, UMR 7057 CNRS Université Paris Diderot, Paris, France, 4Advanced Imaging Center, HHMI Janelia Research Campus, Ashburn, VA, 5Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel B328/P954  Dynamics of A-band assembly within human cardiac myocytes. A.M. Fenix1, S.W. Crawley1, A. Williams1, D. Bader1,2, M.J. Tyska1, D.T. Burnette1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2Medicine, Vanderbilt University Medical Center, Nashville, TN B329/P955  Myosin 18A localizes with myosin 2 at cell: cell junctions in epithelial cells and tissues. K. Remmert1, J. Beach1, J.A. Hammer1; 1Cell Biology and Physiology Center, NIH, NHLBI, Bethesda, MD B330/P956  Regulation of the motor function and cargo transportation of human myosin VIIA by USH1 proteins. T. Sakai1, D. You2, H. Jung3, M. Ikebe1; 1Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, TX, 2Electron Microscopic Research, Korea Basic Science Institute, Daejeon, Korea, 3Biochemistry, Kangwon National University, Chuncheon, Korea B331/P957  High-resolution structural characterization of the myosin VI-F-actin interface during the force generation cycle. P.S. Gurel1, L.Y. Kim1, T. Omabegho2, Z. Bryant2, G.M. Alushin1; 1Cell Biology and Physiology Center, National Heart, Lung, and Blood Institute, Bethesda, MD, 2Department of Bioengineering and Department of Structural Biology, Stanford University School of Medicine, Stanford, CA B332/P958  Re-examining the Roles of Myosin 18A and Actin in Golgi Morphology. K.S. Bruun1, J. Beach1, J.A. Hammer1, K. Remmert1; 1National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD B333/P959  Myosin 10 function in cerebellar Purkinje neurons. Y. Yim1, J. Laakso2, C. Alexander1, M. Mustapha3, R. Cheney4, J. Hammer1; 1Lab of Cell Biology, National Institutes of Health, Bethesda, MD, 2Science Policy, The Endocrine Society, Washington DC, DC, 3 School of Medicine, Stanford University, Palo Alto, CA, 4School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC B334/P960  Development of Pichia pastoris as a model system for Myosin X-induced filopodia formation. P. Tipan1, K. Gousset1; 1Biology, California State University, Fresno, Fresno, CA

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Board No./Presentation No. B335/P961  Harmonic force spectroscopy measures load-dependent kinetics of individual human b-cardiac myosin molecules. J. Sung1, K.I. Mortensen2, S. Nag3, R.D. Vale1, H. Flyvbjerg2, J.A. Spudich3; 1CMP, UCSF, San Francisco, CA, 2Department of Micro- and Nanotechnology, Technical University of Denmark, Kongens Lyngby, Denmark, 3Biochemistry, Stanford University, Stanford, CA B336/P962  Mechanoaccumulative elements of the mammalian actin cytoskeleton. E.S. Schiffhauer1, T. Luo1, K. Mohan2, X. Qian3, V. Srivastava1,4, P. Iglesias2, D.N. Robinson1,5; 1Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Electrical and Computer Engineering, Johns Hopkins University Whiting School of Engineering, Baltimore, MD, 3Biomedical Engineering, Johns Hopkins University Whiting School of Engineering, Baltimore, MD, 4Chemical and Biomolecular Engineering, Johns Hopkins University Whiting School of Engineering, Baltimore, MD, 5Pharmacology and Molecular Science, Johns Hopkins University School of Medicine, Baltimore, MD

B338/P964  Mechanical properties of the lch5 organ of Drosophila. A. Prahlad1, C. Spalthoff2, B. Warren2, D. Kong3, J. Großhans3, M.C. Göpfert2, C.F. Schmidt1; 1Third Institute of Physics - Biophysics, Faculty of Physics, Georg-August University, Göttingen, Germany, 2Department of Cellular Neurobiology, Schwann-Schleiden Research Center, Georg-August University, Göttingen, Germany, 3 Institute of Biochemistry and Molecular Cell Biology, University Medical Center, Georg-August University, Göttingen, Germany B339/P965  Mammalian nonmuscle myosin II binds to anionic phospholipids with concomitant dissociation of the regulatory light chain. S. Shu1, X. Liu1, N. Billington1, C.D. Williamson1, S. Yu1, H.B. Brezska1, J. Donaldson1, J.R. Sellers1, E.D. Korn1; 1NIH, NHLBI, Bethesda, MD B340/P966  Dissecting the role of Myosin VI in the nucleus. N. Fili1, Y. Hari-Gupta1, C.P. Toseland1; 1School of Biosciences, University of Kent, Canterbury, United Kingdom

Microtubule Nucleation and Organization B342/P967  Reconstitution of a minimal microtubule-organizing center using purified centrosome proteins. J.B. Woodruff1, P.O. Widlund2, J. Mahamid3, A.A. Hyman1; 1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 2Department of Chemistry and Biochemistry, University of Gothenburg, Gothenburg, Sweden, 3Max Planck Institute of Biochemistry, Martinsried, Germany B343/P968  The N-terminal domains of gamma-tubulin ring complex proteins define

functional identity of individual GCPs. A. Merdes1, L. Haren1, D. Farache1; 1Centre de Biologie du Developpement, University Toulouse III / CNRS, Toulouse, France B344/P969  Hierarchical Assembly of Centriole Subdistal Appendages. N. Huang1, Y. Xia1, D. Zhang1, J. Teng1, J. Chen1; 1College of Life Sciences, Peking University, Beijing, China B345/P970  MZT1 regulates microtubule nucleation by linking γTuRC assembly to adapter-mediated targeting and activation. R. Ramirez Cota1, N. Teixido-Travesa1, A. Ezquerra1, S. Eibes1, C. Lacasa1, J. Roig2, J. Luders1; 1IRB Barcelona, The Barcelona Institute of Science and Technology, Barcelona, Spain, 2 The Molecular Biology Institute of Barcelona (IBMB-CSIC), Barcelona, Spain B346/P971  Interaction of the activating Casein Kinase 1δ/Hrr25 with the S. cerevisiae γ-Tubulin Ring Complex. M. Moritz1, A. Zelter2, A.F. Brilot1, M.J. MacCoss3, R. Johnson3, T.N. Davis2, D.A. Agard4; 1Biochemistry Biophysics, UCSF, San Francisco, CA, 2Biochemistry, University of Washington, Seattle, WA, 3Genome Sciences, University of Washington, Seattle, WA, 4Biochemistry Biophysics, HHMI/UCSF, San Francisco, CA B347/P972  Spc110p oligomerization drives assembly of the budding yeast γ-tubulin ring complex. A.S. Lyon1, G. Morin2, M. Moritz1, K. Yabut2, T. Vojnar2, A. Zelter2, S. Viswanath3, C. Greenberg3, R. Johnson4, E. Muller2, A. Sali3, M. MacCoss4, T.N. Davis2, D.A. Agard1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 2Biochemistry, University of Washington, Seattle, WA, 3Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, 4Genome Sciences, University of Washington, Seattle, WA B348/P973  Bayesian analysis of FRET to quantitatively measure microtubule nucleation in vivo and in vitro. B.T. Kaye1, T.Y. Yeon1, P.J. Foster1, D.J. Needleman1,2; 1Applied Physics, Harvard University, Cambridge, MA, 2Molecular and Cellular Biology, Harvard University, Cambridge, MA B349/P974  Polarity Sorting of Axonal Microtubules: A Computational Study. E.M. Craig1, H.T. Yeung1, A.N. Rao2, P.W. Baas2; 1Physics, Central Washington University, Ellensburg, WA, 2Neurobiology and Anatomy, Drexel University, Philadelphia, PA B350/P975  Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity. C. Sánchez-Huertas1, F. Freixo1, R. Viais1, C. Lacasa1, E. Soriano2,3,4,5, J. Luders1; 1IRB Barcelona, The Barcelona Institute of Science and Technology, Barcelona, Spain, 2Department of Cell Biology, Faculty of Biology, University of Barcelona, Barcelona, Spain, 3CIBERNED, ISCIII, Madrid, Spain, 4Vall d’Hebron Institute of Research, Barcelona, Spain, 5Institucio Catalana de Recerca i Estudis Avancats (ICREA), Barcelona, Spain

B352/P977  New microtubule growth is regulated at the exits of dendrite branch points. C. Feng1, M.M. Rolls1; 1BMMB, Penn State University, University Park, PA B353/P978  Organization of microtubule nucleation ‘hot spots’ at Golgi stacks. A.A. Sanders1, X. Zhu1, K. Chang1, I. Kaverina1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN B354/P979  Golgi derived microtubule nucleation responds to glucose stimulation in two waves. K.P. Trogden1, I. Kaverina1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN B355/P980  Nuclear anchoring of microtubules by spectraplakin Shot prevents formation of a centrosome-like organizer in Drosophila polyploid cells. T. Sun1, J.C. Pastor-Pareja1; 1School of Life Sciences, Tsinghua University, Peking, China B356/P981  Characterization of a plant-specific microtubule-nucleating protein MACERATOR. S. Schmidt1, A. Smertenko1; 1Institute of Biological Chemistry, Washington State University, Pullman, WA B357/P982  CLASP is Required to Create and Sustain New Microtubules during Array Organization in Arabidopsis. D. Thoms1, L. Vineyard1, V. Kirik2, S.L. Shaw1; 1Biology, Indiana University, Bloomington, IN, 2School of Biological Sciences, Illinois State University, Normal, IL B358/P983  Nemitin is an Essential Microtubule Related Protein. I. Millan1, W. Wang1, Y. Yang1; 1Neurology, Stanford School of Medicine, Stanford, CA B359/P984  Cortical Microtubule Array Architecture in Arabidopsis Hypocotyl Cells. A. Elliott1, S.L. Shaw1; 1Biology, Indiana University Bloomington, Bloomington, IN B360/P985  Mechanisms of microtubule nucleation in spindles. F. Decker1,2, J. Rosenberger2, J. Brugués1,2; 1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 2Max Planck Institute for the Physics of Complex Systems, Dresden, Germany B361/P986  Investigating the role of microtubule minus end proteins in non-centrosomal microtubule organizing centers. J.L. Feldman1, T.D. Skokan1, J. Cade1, C.M. Baumer1; 1Biology, Stanford University, Stanford, CA B362/P987  A Cell Cycle Divorce? Elucidating the Relationship of the DNA Replication and Centriole Duplication Cycles in Differentiated Cells. M. Stratton1, A. Kaiser2, K. Badillo-Rivera3, R. Hannibal3, T. Stearns1,3, J.C. Baker3; 1Biology, Stanford University, Stanford, CA, 2Cancer Biology, Stanford University School of Medicine, Stanford, CA, 3Genetics, Stanford University School of Medicine, Stanford, CA

B351/P976  Wnt pathway players target microtubule regulators to dendrite branch points. A.T. Weiner1, D.Y. Seebold1, N. Michael1, M. Guignet2, C. Kozlowksi1, D. Barbera1, M.M. Rolls1; 1BMMB, Penn State University, University Park, PA, 2Veterinary Medicine, University of California Davis, Davis, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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MONDAY

B337/P963  Melanophilin’s role in crosstalk between actin and microtubule filaments. A. Oberhofer1, Y. Rosenfeld1, W. Stepp1, A. Cleetus1, P. Spieler1, F. Müller-Planitz2, Z. Ökten1; 1Physik-Department E22, Technische Universität München, Garching, Germany, 2 BioMedizinisches Centrum, Molecular Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Monday Poster Session

Board No./Presentation No. B363/P988  Nesprin-1α-dependent microtubule nucleation from the nuclear envelope via Akap450 is necessary for nuclear positioning in myotubes. P. Gimpel1, Y. Lee2, R.M. Sobota2, A. Calvi2, S. Shackelton3, K. Mamchaoui1, F. Nedelec4, J. Schmoranzer5, B. Burke2, B. Cadot1, E.R. Gomes6; 1UMR974, Center of Research in Myology, Paris, France, 2 IMB, A*Star, Singapore, Singapore, 3Department of Molecular and Cell Biology, University of Leicester, Leicester, United Kingdom, 4Cell Biology and Biophysics UnitCe, EMBL, Heidelberg, Germany, 5Charité, Universitätsmedizin Berlin, Berlin, Germany, 6Universidade de Lisboa, IMB, Lisbon, Portugal B364/P989  Stability and function of a putative microtubule organizing center in the human parasite Toxoplasma gondii. J.M. Leung1, Y. He1, F. Zhang2,3, Y. Hwang3,4, E. Nagayasu3,5, J. Liu1, J. Murray1,3, K. Hu1; 1Biology, Indiana University, Bloomington, IN, 2Molecular and Cellular Pharmacology, University of Miami, Miller School of Medicine, Miami, FL, 3Cell and Developmental Biology, University of Pennsylvania, School of Medicine, Philadelphia, PA, 4 Nikon Instruments Inc, Melville, NY, 5Infectious Diseases, University of Miyazaki, Miyazaki, Japan B365/P990  A Conserved Motif in Centrosomin’s Carboxyl Terminus, Sufficient for PCM localization, Interacts Directly with Two Binding Partners. R. Citron1, M. Kelly1, N.M. Rusan2, B. Huang1, D.A. Agard1; 1Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, 2 Physiology Center, National Heart, Lung and Blood Institute, Bethesda, MD B366/P991  Coordinating microtubule organization with cell cycle state. M.D. Sallee1, J.L. Feldman1; 1Biology, Stanford University, Palo Alto, CA

Cilium Structure, Composition, and Motility B367/P992  α-tubulin isotype orchestrates ciliary microtubule architecture, IFT, and extracellular vesicle biology. M. Silva1, N.S. Morsci 1, K.C. Nguyen2, C.G. Rongo1, D.H. Hall 2 , M.M. Barr1; 1Genetics, Rutgers University, Piscataway, NJ, 2Center for C. elegans Anatomy, Albert Einstein College of Medicine, Bronx, NY B368/P993  FUNCTIONS of the TOG domain proteins, FAP256 and CHE-12, at the ciliary tip. P. Louka1, M. Guha1, K. Vasudevan2, D. Włoga3, W.L. Dentler4, J. Gaertig1; 1Cellular Biology, University of Georgia, Athens, GA, 2 Biology, Stanford University, Stanford, CA, 3 Cell Biology, Nencki Institute of Experimental Biology, Warszawa, Poland, 4Molecular Biosciences, University of Kansas, Lawrence, KS B369/P994  The function of Wdr protein in motile cilia central pair microtubules assembly/stability. L. Zhu1, J. Zheng1, X. Yan1, X. Zhu1; 1Shanghai institute of biochemistry and cell biology, Shanghai, China

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Monday Poster Session B370/P995  SPEF1 Imparts Mechanical Stability To The Central Pair Microtubules In Cilia. M. Guha1, Y. Jiang1, K.K. Vasudevan2, J. Gaertig1; 1Department of Cellular Biology, The University of Georgia, Athens, GA, 2Department of Biology, Stanford University, Stanford, CA B371/P996  Repair of the split neck of the HSP40-minus radial spoke complex in flagella. X. Zhu1, E. Poghosyan2, T. Ishikawa2, R. Kamiya3,4, P. Yang1; 1Department of Biological Sciences, Marquette University, Milwaukee, WI, 2Biomolecular Research Laboratory, Paul Scherrer Institute, Villigen, Switzerland, 3 Department of Biological Sciences, University of Tokyo, Tokyo, Japan, 4Department of Life Science, Gakushuin University, Tokyo, Japan B372/P997  Biochemical and structural analysis of Chlamydomonas mutants reveals heterogeneity among the radial spokes. E.E. Dymek1, A. Dai2, D. Nicastro2, E.F. Smith1; 1Biological Sciences, Dartmouth College, Hanover, NH, 2Universtity of Texas Southwestern Medical Center, Dallas, TX B373/P998  Characterization of a putative Ca2+ binding protein FAP85 of Chlamydomonas flagella. J. Kirima1, H. Kojima2, K. Oiwa1,2; 1Graduate School of Life Science, University of Hyogo, Harima, Japan, 2Advanced ICT Research Institute, National Institute of Information and Communications Technology, Kobe, Japan B374/P999  IQ and Ubiquitin domain containing protein (Iqub) is required for sperm axoneme stability and flagellar motility. S.J. Scales1, J. Singh1, A.M. De Maziere2, G. Posthuma2, N. Gupta1, L. Ta3, J. Goldsmith3, M. Reichelt4, F. Chu4, O. Foreman4, X.Y. Rairdan3, J. Klumperman2; 1Molecular Biology, Genentech, South San Francisco, CA, 2Cell Biology and Institute of Biomembranes, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands, 3Transgenic Technology, Genentech, South San Francisco, CA, 4Pathology, Genentech, South San Francisco, CA B375/P1000  Spatiotemporally decoding tubulin codes inside primary cilia and revealing their roles in intraflagellar transport and ciliary signaling. C. Wang1, Y. Chang2, Y. Chnag2, S. Huang2, C. Lin3, H. Cheng3, Y. Chiang4, W. Huang2, E. Su5, T. Inoue6, Y. LIN1; 1Institute of Molecular Medicine, National Tsing Hua University, Hsinchu City, Taiwan, 2 Department of Life Science, National Tsing Hua University, Hsinchu City, Taiwan, 3Department of Medical Science, National Tsing Hua University, Hsinchu City, Taiwan, 4Interdisciplinary Program of Science, National Tsing Hua University, Hsinchu City, Taiwan, 5Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 6Department of Cell Biology, Johns Hopkins University, Baltimore, Baltimore, MD

B376/P1001  The Chlamydomonas pf23 mutant carries a deletion in the DYX1C1 gene and fails to assemble the majority of the inner dynein arms in the ciliary axoneme. R. Yamamoto1, J.M. Obbineni2, L.M. Alford3, T. Ide4, M. Owa4, T. Kon1, K. Inaba5, N. James6, S.M. King7, T. Ishikawa2, W.S. Sale3, S.K. Dutcher6; 1Biological Sciences, Osaka University, Osaka, Japan, 2Bimolecular Research, Paul Scherrer Institute, Zurich, Switzerland, 3 Cell Biology, Emory University, Atlanta, GA, 4 Biological Sciences, University of Tokyo, Tokyo, Japan, 5Shimoda Marine Research Center, University of Tsukuba, Shizuoka, Japan, 6Genetics, Washington University School of Medicine, St. Louis, MO, 7Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT B377/P1002  The Chlamydomonas IDA3 gene encodes a protein specifically required for transport of the ciliary inner dynein arm I1/f dynein. E.L. Hunter1, J. Hwang1, L.M. Alford2, R. Yamamoto3, R. Kamiya4, H. Lin5, F. Yang6, M. Wirschell6, S.K. Dutcher5, W.S. Sale1; 1Cell Biology, Emory University School of Medicine, Atlanta, GA, 2Biology, Oglethorpe University, Atlanta, GA, 3Biological Sciences, Osaka University, Osaka, Japan, 4Biological Sciences, Chuo University, Tokyo, Japan, 5Genetics, Washington University School of Medicine, St. Louis, MO, 6Biochemistry, University of Mississippi Medical Center, Jackson, MS B378/P1003  Phosphorylation of DCC1 regulates outer dynein arm function and mediates alcohol-induced ciliary dysfunction. F. Yang1, C. Scarbrough1, J. Pavlik2, J. Sisson2, M. Wirschell1; 1Biochemistry, University of Mississippi Medical Center, Jackson, MS, 2Pulmonary, Critical Care, Sleep and Allergy, University of Nebraska Medical Center, Omaha, NE B379/P1004  The Transition Zone Superassembly is Altered by Joubert Syndrome Mutations. G. Garcia1, X. Shi1,2, B. Huang1,2, J.F. Reiter1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 2Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA B380/P1005  Membrane-associated localization and interactomic study of primary cilia. P. Kohli1,2, M. Rinschen1,2,3, M. Hoehne1,2,3, T. Benzing1,2,3, B. Schermer1,2,3; 1Department II of Internal Medicine and Center for Molecular Medicine, University of Cologne, Cologne, Germany, 2Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany, 3Systems Biology of Ageing Cologne, University of Cologne, Cologne, Germany B381/P1006  Investigating novel antibodies for identification/characterization of neuronal primary cilia using immunofluorescence microscopy. G. Cook1, J. Cox1,2, N. Wilson1; 1Anatomy Cell Biology, Oklahoma State University-Center for Health Sciences, Tulsa, OK, 2Biological Sciences, Tulsa Community College, Tulsa, OK

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B382/P1007  IIIG9: a new ciliary protein in ependymal cells. K.A. Salazar 1,2, V.M. Baeza1,2, F.A. Martinez1,2, F.J. Nualart1,2, M.J. Oviedo1,2, M. Cifuentes3; 1Cell Biology, Concepcion University, Concepcion, Chile, 2Center for Advanced Microscopy, CMA BIO BIO, Concepcion, Chile, 3CIBER BIONAND, Malaga University, Malaga, Spain B383/P1008  Flagellar Control Units Are Organized into Distinct Nanodomains that Define Sperm Motility Pattern as Revealed by Super Resolution Microscopy. N. Mannowetz1, M.R. Miller1, S.J. Kenny2, S.A. Mansell1, S. . Meyers3, K. Xu2, P.V. Lishko1; 1Department of Molecular and Cell Biology, University of California, Berkeley, CA, 2Department of Chemistry, University of California, Berkeley, CA, 3 Department of Physiology and Cell Biology, University of California, Davis, CA B384/P1009  Functions of Ttc26 in cilia motility. Y. Xu1, S. Huang1, D. Feng1, X. Yan1, X. Zhu1; 1Shanghai institute of biochemistry and cell biology, Shanghai, China

B386/P1011  Flagellar length control can be achieved through a simple diffusion-based length measure. N.L. Hendel1, W.F. Marshall1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B387/P1012  Quantitative Proteomics Analysis of Chlamydomonas Axonemes Reveal Proteins Enriched in Short Axonemes. J. Hwang1, L.M. Alford2, R. Bower3, E.L. Hunter1, M.E. Porter3, W.S. Sale1; 1Cell Biology, Emory University School of Medicine, Atlanta, GA, 2 Biology, Oglethorpe University, Atlanta, GA, 3 Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN B388/P1013  Biochemical analysis reveals the molecular composition of kinetodesmal fibers and other cortical structures of the ciliated protozoan Tetrahymena Thermophila. J.E. Honts1, A. Fiscus1, N. Skantz1, L. Sundby1, D. Chalker2, A. Aboona2, C. Brenner2, V. Jaspan2, H. Pravder2, D.J. Beussman3, Z. Turner3, M. Dahl3, R. Somepalli2; 1Biology, Drake University, Des Moines, IA, 2Biology, Washington University, St. Louis, MO, 3Chemistry, St. Olaf College, Northfield, MN B389/P1014  Generation and modulation of sperm flagellar motility by metachronal and synchronous sliding of doublet microtubules. S. Ishijima1, K. Yoshida2, G.L. Takei3, M. Fujinoki3; 1Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan, 2 Biomedical Engineering, Toin University of Yokohama, Yokohama, Japan, 3Physiology, Dokkyo Medical University, Tochigi, Japan

Spindle Assembly 2 B400/P1015  Multivariate image analysis reveals architectural features of Xenopus spindles assembled in vitro. A.W. Grenfell1, M. Strzelecka1,2, M. Crowder1,3, K. Helmke1,4, A. Schlaitz1,5, R. Heald1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Qiagen, Hilden, Germany, 3Molecular and Cell Biology, University of California, Davis, Davis, CA, 4Bioengineering Department, Stanford University, Stanford, CA, 5Zentrum für Molekulare Biologie, Unversitlät Heidelberg, Heidelberg, Germany B401/P1016  Theory of Xenopus Llaevis meiotic spindle assembly. S. Fürthauer1,2,3, P.J. Foster3, D.J. Needleman3, M.J. Shelley1,2; 1Simons Foundation, Simons Foundation, New York, NY, 2Courant Institute, New York University, New York, NY, 3Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA B402/P1017  Mechanisms of spindle size scaling across Pipid frogs. K. Miller1, R. Heald1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA B403/P1018  Phosphorylation of EB2 by Aurora B and CDK1 reduces the affinity for MTs and ensures mitotic progression and genome stability. M. Iimori1, S. Nishimura2, E. Oki2, H. Saeki2, H. Kitao1, Y. Maehara2; 1Department of Molecular Oncology, Kyushu University, Fukuoka, Japan, 2Department of Surgery and Science, Kyushu University, Fukuoka, Japan B404/P1019  GTSE1 is a novel regulator of chromosome alignment during mitosis. A.R. Tipton1, J.R. Daum1, J.D. Wren2, G.J. Gorbsky1; 1Cell Cycle and Cancer Biology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK B405/P1020  Physical determinants of bipolar mitotic spindle assembly and stability. R. Blackwell1, C. Edelmaier1, O. SweezySchindler1, A. Lamson1, Z. Gergely1,2, E.T. Otoole2, A. Crapo1, L. Hough1, M.A. Glaser1, J.R. McIntosh2, M. Betterton1,2; 1Physics, University of Colorado Boulder, Boulder, CO, 2MCDB, University of Colorado Boulder, Boulder, CO B406/P1021  Local load-bearing in the mammalian spindle provides mechanical isolation and redundancy. M.W. Elting1, D.B. Udy1,2, S. Dumont1,3; 1Cell and Tissue Biology, UCSF, San Francisco, CA, 2(present address) Molecular and Cellular Biology Program, University of Washington, Seattle, WA, 3Cellular and Molecular Pharmacology, UCSF, San Francisco, CA B407/P1022  Microtubules push chromosomes apart in anaphase. C. Yu1, S. Redemann2, H. Wu3, T. Yoo1, T. Müller-Reichert2, D.J. Needleman1,4; 1School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 2Medical Faculty Carl Gustav Carus, Technische Universität, Dresden, Germany, 3 Physics, Harvard University, Cambridge, MA, 4 Molecular and Cellular Biology and Center for Systems Biology, Harvard University, Cambridge, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B408/P1023  Bipolar spindle formation is an irreversible process mediated by kinesin-5 crosslinking. A.Y. Leary1,2, E. Nazarova1, S. Sim2, S. DeWald3, M.K. Gardner3, E.T. Otoole4, P. Francois2, J.M. Vogel1; 1Biology, McGill University, Montreal, QC, 2Physics, McGill University, Montreal, QC, 3Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, 4Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO B409/P1024  An alternate pathway for the degradation of cyclin B1 that mediates mitotic slippage. R.S. Balachandran1, C.S. Heighington1, N.G. Starostina1, J.W. Anderson1, D.L. Owen1, S. Vasudevan1, E.T. Kipreos1; 1Department of Cellular Biology, University of Georgia, Athens, GA B410/P1025  HMMR/RHAMM balances motor forces needed to complete the spindle assembly checkpoint. H. Chen1, C.A. Maxwell1; 1Paediatrics, University of British Columbia, Vancouver, BC B411/P1026  Different Mad1 domains coordinate to catalyze Mad2 O-C conversion. W. Ji1, E. Ahmad1, S. Liu1, Y. Luo1; 1Biology, The University of Toledo, Toledo, OH B412/P1027  Mechanism Selecting Against Unfit Cells with Poor Mitosis. C. Fong1, G. Mazo1, T. Das1, J. Goodman2, M. Kim1, D. Izquierdo1, M.B. Tsou1; 1Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY, 2 Oberlin College, Oberlin, OH B413/P1028  Mitotic spindle organization and dynamics respond to unresolved sister chromatids via an Aurora B-dependent pathway. B. Zipp1, R. Kyger1, N. Lewis1, K.B. Kaplan1, C. Jaramishian1; 1MCB, University of California, Davis, Davis, CA B414/P1029  A new tool for identifying substrates of Aurora kinases. J. Deretic1, A.R. Kerr1, T. Ly2, J.P. Welburn1; 1The Wellcome Trust Centre for Cell Biology and Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom, 2Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee, United Kingdom B415/P1030  An actin spindle protects mammalian oocytes against chromosome segregation errors. B. Mogessie1, M. Schuh1; 1Meiosis, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany B416/P1031  Cortical tension and chromosome alignment in mouse oocytes. I. Bennabi1; 1CIRB, Collège de France, CNRS, INSERM-U1050, PSL, Paris, France B417/P1032  Minus-end kinesins and SPD1(PRC1) provide complementary mechanisms to organize acentriolar C. elegans oocyte spindles. T.J. Mullen1, I.D. Wolff1, S.M. Wignall1; 1Molecular Biosciences, Northwestern University, Evanston, IL B418/P1033  SAMP-1 is essential for chromosome segregation during C. elegans male meiosis. A. Kuzmanov1, A.J. Deshong1, B.J. Larson1, M. Gorjanacz2, J. Engebrecht1; 1Molecular and Cellular Biology, University of California, Davis, CA, 2European Molecular Biology Laboratory, Heidelberg, Germany

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B385/P1010  In vivo analysis of Outer Dynein Arm transport by IFT in Chlamydomonas reinhardtii. J. Dai1, D.R. Mitchell2, K.F. Lechtreck1; 1Department of Cellular Biology, University of Georgia, Athens, GA, 2Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY

Monday Poster Session

Board No./Presentation No.

G1, G1-S, S, and G2-M Phase Regulation B419/P1034  Spatiotemporal variations of the human proteome associated to cell cycle progression. D. Mahdessian1, D.P. Sullivan1, E. Rexhepaj1, R.F. Murphy2, M. Uhlén1, E. Lundberg1; 1Science for Life Laboratory,, Royal Institute of Technology (KTH), Stockholm, Sweden, 2Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA B420/P1035  Yeast metabolic cycle: the relationship between metabolic state and the cell cycle at single-cell resolution. A.J. Burnetti1,2,3, N.E. Buchler3,4; 1University Program in Genetics and Genomics, Duke University, Durham, NC, 2Cell and Molecular Biology Program, Duke University, Durham, NC, 3Center for Genomic and Computational Biology, Duke University, Durham, NC, 4Biology, Duke University, Durham, NC B421/P1036  Investigation of multi-site phosphorylation in γ-tubulin in budding yeast. K. Shulist1, E. Yen1, J.M. Vogel1; 1Department of Biology, McGill University, Montreal, QC B422/P1037  A novel signaling pathway triggers cell cycle arrest in response to mitotic stresses generated by centrosome loss or prolonged mitosis. B.G. Lambrus1, V. Daggubati1, Y. Uetake2, P. Scott1, K.M. Clutario1, G. Sluder2, A.J. Holland1; 1Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 2Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA B423/P1038  53BP1 and USP28 Mediate p53 Activation and G1 Arrest Following Centrosome Loss or Extended Mitotic Duration. F. Meitinger1, J.V. Anzola2, M. Kaulich3, A.K. Richardson1, J.D. Stender4, C. Benner5, C.K. Glass4,5, S.F. Dowdy4, A.B. Desai1, A.K. Shiau2, K. Oegema1; 1Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, La Jolla, CA, 2Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA, 3Institute of Biochemistry II, Goethe University Frankfurt,, Frankfurt, Germany, 4Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 5Department of Medicine, University of California San Diego, La Jolla, CA B424/P1039  CRISPR/Cas9 treatment induces an extended p53-dependent cell cycle arrest in human cells. J.M. Geisinger1, T. Stearns1,2; 1Biology, Stanford University, Stanford, CA, 2Genetics, Stanford University, Stanford, CA B425/P1040  Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. F.M. Feringa1, L. Krenning1, A. Koch1, J. van den Berg1, B. van den Broek1, K. Jalink1, R.H. Medema1; 1Cell Biology, Netherlands Cancer Institute, Amsterdam, Netherlands B426/P1041  ER-resident transmembrane transcription factor OASIS plays important role in DNA damage response. R. Asada1, K. Kikushima1, M. Cui1, K. Imaizumi1; 1Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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Monday Poster Session B427/P1042  Pre-exposure to environmental stress alters survival under DNA replication instability. P.N. Patel1, S.A. Sabatinos1; 1Department of Chemistry and Biology, Ryerson University, Toronto, ON B428/P1043  Defining phenotypic heterogeneity and predicting cell fate post-drug in fission yeast. S.A. Sabatinos1,2, M.D. Green1, S.L. Forsburg1; 1Molecular and Computational Biology, University of Southern California, Los Angeles, CA, 2Chemistry and Biology, Ryerson University, Toronto, ON B429/P1044  Role of the voltage-gated calcium channel β4 subunit in cell proliferation. M. Rima1,2,3, M. Daghsni1,2,4, Z. Fajloun3, M. Berrios5, M. Ronjat1,2,6, Y. Mori7, J.L. Bruses5, M. De Waard1,2,6,8; 1INSERM - UMR1087, Institute of Thorax, Nantes, France, 2CNRS - UMR6291, Institute of Thorax, Nantes, France, 3Azm Center for Research in Biotechnology and its Application, Lebanese University, Tripoli, Lebanon, 4Laboratory of Human Genetics, University of Tunis El Manar, Tunis, Tunisia, 5Department of Natural Sciences, Mercy College, Dobbs Ferry, NY, 6LabEx Ion Channels Science and Therapeutics, University of Nantes, Nantes, France, 7Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Kyoto, Japan, 8Smartox Biotechnology, SaintMartin d’Hères, France B430/P1045  The molecular mechanisms that maintain the numerical integrity of centrosomes under stress. T. Nakamura1, M. Takekawa1; 1Division of cell signaling and molecular medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan B431/P1046  Polo kinase has an important role in establishing meiotic commitment in Saccharomyces cerevisiae. C. Puccia1, S. Lacefield1; 1Biology, Indiana University, Bloomington, IN B432/P1047  Oocytes from older females progress through meiosis faster than younger. M. Koncicka1, A. Tetkova1, D. Jansova1, M. Kubelka1, A. Susor1; 1Laboratory of Biochemistry and Molecular Biology of Germ Cells, IAPG CAS, Libechov, Czech Republic B433/P1048  Mitotic Cyclin Dependent Kinase Links Septin Organization and Spindle Positioning. G. Muhire Gihana1, T. Musser1, O. Thompson1, S. Lacefield1; 1Biology, Indiana University, Bloomington, IN B434/P1049  Irreversible APC/C-Cdh1 inactivation underlies the point of no return for cell cycle entry. S.D. Cappell1, M. Chung1, A. Jaimovich1, S.L. Spencer1, T. Meyer1; 1Chemical and Systems Biology, Stanford School of Medicine, Stanford, CA B435/P1050  Inappropriate E2F activity during S phase deregulates replication dynamics. B.R. Pennycook1, R.A. de Bruin1; 1Laboratory for Molecular Cell Biology, University College London, London, United Kingdom B436/P1051  Role of the VCP segregase in DNA replication. P. Ubieto-Capella1,2, E. Lecona1, O. Fernández-Capetillo1; 1Genomic Instability Group, Spanish National Cancer Research Centre, CNIO, Madrid 28029, Spain, 2 “Programa Impuls”, University of Lleida, UdL, Lleida 25008, Spain

B437/P1052  The cullin-1 gene in Aspergillus nidulans interacts genetically with γ-tubulin, regulates the G1/S transition, and coordinates nuclear division with cytokinesis. V. Paolillo1, J. Dohn1, B.R. Oakley1; 1Molecular Biosciences, The University of Kansas, Lawrence, KS B438/P1053  Dihydro derivatives of dehydroleucodine inhibit early adipogenesis. S. Abood1, D. Llomparr1, M. Veisaga2, L.A. Lopez3, M.A. Barbieri1,2,4,5; 1Department of Biological Sciences, Florida International University, Miami, FL, 2Biomolecular Sciences Institute, Florida International University, Miami, FL, 3Laboratory of Cell Cycle and Cytoskeleton, Instituto de Histología y Embriología Dr. M. H. Burgos (IHEM), Facultad de Ciencias Medicas, Universidad Nacional de Cuyo, Mendoza, Argentina, 4Fairchild Tropical Botanic Garden, Coral Gables, FL, 5International Center of Tropical Botany, Florida International University, Miami, FL B439/P1054  Telomere defects in cdc13-1 strains at permissive temperatures. P. Sanchez1, K. Livingston1, W. Azaizeh1, K. Edwards1, A. Nakasone1, C.J. Hengartner1, L.R. Vega1; 1Biology, Barry University, Miami Shores, FL

Kinetochore Assembly and Functions 2 B440/P1055  Characterizing the role of BuGZ in mitotic chromosome segregation. H.K. Shirnekhi1, J.G. DeLuca1; 1Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B441/P1056  Investigating the contribution of phospho-Histone marks to Aurora B kinase activity at kinetochores. A.J. Broad1, J.G. DeLuca1, K. Luger1, M. Dechassa1; 1Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B442/P1057  Sex-specific survival differences in p53 heterozygous animals reveal that p53 is not required for cell death and tumor suppression caused by high rates of chromosomal instability. L.C. Funk1,2, J. Wan3, S.D. Ryan4, B.A. Weaver4,5, C. Kaur4; 1Molecular and Cellular Pharmacology, UW-Madison, Madison, WI, 2Cancer Biology, UW-Madison, Madison, WI, 3Physiology Graduate Training Program, UW-Madison, Madison, WI, 4Cell and Regenerative Biology, UW-Madison, Madison, WI, 5Carbone Cancer Center, UW-Madison, Madison, WI B443/P1058  Optogenetic tools for controlling kinetochore function in live cells. H. Zhang1, C. Aonbangkhen2, A. Gokden1, D.M. Chenoweth2, M.A. Lampson1; 1Department of Biology, University of Pennsylvania, Philadelphia, PA, 2Department of Chemistry, University of Pennsylvania, Philadelphia, PA B444/P1059  Multi-target Mps1 phosphorylation cascade in spindle checkpoint revealed by in-vitro reconstitution. Z. Ji1, H. Gao1, L. Jia1, B. Li1, H. Yu1,2; 1Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, 2Howard Hughes Medical Institute, Dallas, TX

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B445/P1060  Centromere structure, not transcription, regulates Aurora B localization and SAC response in human cells. C. Ferras1, N. Galjart2, M. Cruz1, H.J. Maiato1,3; 1CID lab, IBMC, I3S, Porto, Portugal, 2Genetics, Erasmus MC, Rotterdam, Netherlands, 3Cell Division Unit, Department of Experimental Biology, FMUP, UP, Porto, Portugal B446/P1061  Characterization of CENP-A nucleosome-binding factors and their role in epigenetic centromere maintenance. B.T. French1, F.G. Westhorpe1, A.F. Straight1; 1Biochemsitry, Stanford University Medical School, Stanford, CA

B448/P1063  The Number of Satellite Repeats Dictates Centromere Strength in Mammals. J.M. Dawicki-McKenna1, A. Iwata-Otsubo2, S.J. Falk1, K. Yang2, L. Chmatal2, R.M. Schultz2, M.A. Lampson2, B.E. Black1; 1Department of Biochemistry and Biophysics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 2Department of Biology, University of Pennsylvania, Philadelphia, PA B449/P1064  Kinetoplastid Ndc80/Nuf2 reunites chromosome segregation across eukaryotes. S. D’Archivio1, B. Wickstead1; 1School of Life Sciences, University of Nottingham, Nottingham, United Kingdom B450/P1065  Mitotic Chromosome Proteome of nucleoporin Seh1 conditional knockout cell line using Auxin/AID system. M. Platani1, I. Samejima1, W.C. Earnshaw1; 1Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom B451/P1066  Molecular Basis for Cdk1 Mediated Cell Cycle Control of Mis18 Complex Assembly. F. Spiller1, B. Medina-Pritchard1, M. Abad Fernandez1, M. Wear2, O. Molina1, W.C. Earnshaw1, J. Arulanandam1; 1Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom, 2Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom B452/P1067  Investigating the centromeric role of HP1 by a synthetic biology approach. J.G. Ruppert1, O. Molina1, J. Arulanandam1, W.C. Earnshaw1; 1Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom B453/P1068  Molecular force measurements across the kinetochore protein CENP-T. A. Freikamp1, A. Weißl2, M. Rief2, C. Grashoff1; 1Molecular Mechanotransduction, Max Planck Institute of Biochemistry, Martinsried/Munich, Germany, 2Biophysics (E22), Technische Universität München, Munich, Germany

B454/P1069  Atypical functions of BUB-1 and HCP-1/2CENP-F during mitosis in Caenorhabditis elegans. F. Edwards1,2, J. Dumont1; 1Institut Jacques Monod, CNRS UMR7592, Paris, France, 2ED Frontières du vivant, Centre de recherches interdisciplinaires, Paris, France

Centrosome Assembly and Functions 2 B455/P1070  A Detailed Centrosome Interactome Reveals A Novel Role Of Plk4 And Provides Insight Into The Mechanisms Of Human Centrosome Disease. B.J. Galletta1, C.J. Fagerstrom1, T.A. Schoborg1, T.A. McLamarrah2, J.M. Ryniawec2, D.W. Buster2, K.C. Slep3, G.C. Rogers2, N.M. Rusan1; 1Cell Biology and Physiology Center, National Heart Lung and Blood Institute, Bethesda, MD, 2Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, 3Biology, University of North Carolina, Chapel Hill, NC B456/P1071  The role of centrosomes in the pathogenesis of Zika virus (ZIKV)-related microcephaly. Y. Yaffe1, T.A. DelliboviRagheb1, Y. Chen1, Y. Elkabetz2, N. Altan-Bonnet1; 1National Heart Lung and Blood Institute, NIH, Bethesda, MD, 2Department of Cell and Developmental Biology, Tel Aviv University, Tel Aviv, Israel B457/P1072  Accessorizing the centriole: Understanding distal appendage proteins and analyzing molecular evolution of centriolar adjuncts. O. Cormier1, T. Stearns1,2; 1Biology, Stanford University, Stanford, CA, 2Genetics, Stanford School of Medicine, Stanford, CA B458/P1073  Sfi1 and Centrin functions in centrosome biogenesis and separation. I.B. Bouhlel1, M. Ohta2, A. Mayeux1, N. Bordes1, F. Dingli1, J. Boulanger1, G. Velve Casquillas3, D. Loew1, P.P. Tran1, M. Sato2, A. Paoletti1; 1UMR144, Institut Curie, Paris, France, 2 Center for Frontier Research, National Institute of Genetics, Mishima, Japan, 3ELVESYS Microfluidic Innovation Center, Paris, France B459/P1074  Deciphering the proteomic composition of pericentriolar satellites. V. Quarantotti1, J. Chen1, J. Haefner1, C. Taylor1, E.K. Papachristou1, C. d’Santos1, J.V. Kilmartin2, M. Miller1, F. Gergely1; 1Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom, 2MRC Laboratory of Molecular Biology, Cambridge, United Kingdom B460/P1075  Spindle pole body assembly into the nuclear envelope in budding yeast. J. Chen1, Z. Yu1, S.E. Smith1, J. Unruh1, S.L. Jaspersen1; 1Stowers Institute for Medical Research, Kansas City, MO B461/P1076  Plk1 controls PCM assembly by phosphorylating SPD-2 and SPD-5 in C. elegans. Z. Zhao1, S. Wang1,2, D. Wu3, S. Ochoa Mikrut1,4, V. Viscardi1, A.B. Desai1,4, K. Oegema1,4; 1Ludwig Institute For Cancer Research, La Jolla, CA, 2National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, 3The National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 4University of California, San Diego, La Jolla, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B462/P1077  Defining the link between p53 and centrosome homeostasis. R. Sala1, N. Raj2, L. Attardi2,3, T. Stearns1,3; 1Biology Department, Stanford University, Stanford, CA, 2 Department of Radiation Oncology, Stanford University, Stanford, CA, 3Department of Genetics, Stanford University, Stanford, CA B463/P1078  GAS2L1 Is a Centriolar Protein to Regulate Centrosome Disjunction. F. Au1, Y. Jia1, K. Jiang2, I. Grigoriev2, K. Hau1, S. Du3, A. Akhmanova2, .Z. Qi1; 1Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong, 2Cell Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands, 3Department of Physics and Super-Resolution Imaging Center, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong B464/P1079  Paracrine-mediated invasion induced by centrosome amplification. T. Arnandis1, V. Rajeeve2, C.H. Brennan3, P.R. Cutillas2, S.A. Godinho1; 1Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University, London, United Kingdom, 2Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University, London, United Kingdom, 3School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom B465/P1080  DDR1 localisation to adherens junctions prevents efficient clustering of supernumerary centrosomes. A.D. Rhys1, M. Vaghela2, P. Monteiro1, M. Yusuf1, A.D. McAinsh3, G. Charras2, S.A. Godinho1; 1Molecular Oncology, Barts Cancer Institute, Queen Marys, University of London, London, United Kingdom, 2London Centre for Nanotechnology, University College London, University of London, London, United Kingdom, 3Division of Biomedical Cell Biology, University of Warwick, Warwick, United Kingdom B466/P1081  The function of TgCentrin2 in the apicomplexan parasite Toxoplasma gondii. J. Liu1, J.M. Leung1, L.A. Wetzel1,2, Y. Zhang3, J. Murray1, L. Florens3, K. Hu1; 1Biology, Indiana University, Bloomington, IN, 2Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 3Stowers Institute for Medical Research, Kansas City, MO B467/P1082  HSP70 is required for the assembly of functional mitotic spindles. C. Fang1, H. Kuo1, L. Yih1; 1Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan

Cancer Therapy 2 B468/P1083  Temporal design of cancer combinatorial therapy guided by single-cell dynamics. S. Chen1,2, G. Lahav1; 1Systems Biology, Harvard Medical School, Cambridge, MA, 2Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan B469/P1084  Defining the signaling space of p53 dynamics across species and tumors reveals cell line specific modifiers of p53 activity. J. Stewart-Ornstein1, G. Lahav1; 1Systems Biology, Harvard Medical School, Boston, MA

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MONDAY

B447/P1062  Testing the Functional Relevance of Putative Post-translational Modifications of the Histone Variant, CENP-A, using a CRISPR-based Method for Simultaneous Replacement of Both CENP-A Alleles. G.A. Logsdon1,2, D. Fachinetti3, E.B. Selzer1, A. Abdullah3, D.W. Cleveland3, B.E. Black1,2; 1Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2Graduate Program in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 3Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA

Monday Poster Session

Board No./Presentation No. B470/P1085  Regulation of endocytosis by ultrasound and microbubble treatment: potential for control of drug uptake in cancer cells. F. Fekri1,2, R.C. Delos Santos 1, R. Karshafian1,2, C.N. Antonescu1; 1Chemistry Biology, Ryerson University, Toronto, ON, 2IBEST, Li Ka Shing Knowledge Institute, Toronto, ON B471/P1086  Characterization of a novel anti-cancer drug that targets centrosomes in cancer cells. D. Jaunky1, P. Forgione2, A.J. Piekny1; 1Biology, Concordia University, Montreal, QC, 2Chemistry and Biochemistry, Concordia University, Montreal, QC B472/P1087  Spreading and motility of normal and cancer cells under the action of anti-microtubule drugs – dose-response relation. S. Kauanova1, A. Tvorogova2, A. Kakpenova3, A. Balabiyev3, M. Abdukassimova4, S. Mussakhan4, I.A. Vorobjev2,3,4; 1School of Engineering, Nazarbayev University, Astana, Kazakhstan, 2Faculty of Biology, M.V. Lomonosov Moscow State University, Department of Cell Biology and Histology, A.N. Belozersky Institute of Physico-Chemical Biology, Moscow, Russia, 3National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan, 4School of Science and Technology, Nazarbayev University, Astana, Kazakhstan B473/P1088  Quantification of oridonin-induced apoptosis and cytotoxicity in cancer cells using noninvasive live-cell imaging. J.E. Clayton1, P.G. Held1, B. Larson1, P. Banks1; 1BioTek Instruments, Winooski, VT B474/P1089  Establishing and analyzing clinically radioresistant oral squamous cell cancer cells. N. Yamamoto1, G. Kashino2, K. Kawano1, S. Kobashikawa2; 1Department of Dentistry and Oral-Maxillo-Facial Surger, Oita University, Yufu, Japan, 2Advanced Molecular Imaging Center, Oita University, Yufu, Japan B475/P1090  Effect of potential anticancer compounds on osteoblast cell death and apoptosis is reduced by human breast cancer cell derived PTHrP. N.S. Datta1, S. Sharma1; 1Internal Medicine, Wayne State University School of Medicine, Detroit, MI B476/P1091  Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-Akt signaling following MEK inhibition in metastatic triple negative breast cancer. J. Kwon1, C. Choi1, D.M. Helfman1; 1Department of Biological Sciences, Korea Institute of Science and Technology, Daejeon, Korea, South B477/P1092  Bay 61-3606 sensitizes TRAILinduced apoptosis by downregulating Mcl-1 in breast cancer cells. S. Kim1, S. Park1, K. Kim1,2, I. Kim1,2; 1ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Korea, 2 Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, Korea B478/P1093  Cynanchi atrati Radix sensitizes human glioma cells to TRAIL-induced apoptosis. S. Lee1, H. Byun1, M. Won1, K. Park1, K. Kang1, G. Hur1; 1Department of Medical Science, Chungnam National University School of Medicine, Daejeon, Korea, South

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Monday Poster Session B479/P1094  Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAILinduced apoptosis via calpain-mediated Bax cleavage. S.S. Park1,2, S.H. Shin1, E.J. Ju1, I. Park1, S.Y. Song1,3, S.Y. Jeong1,2, E.K. Choi2,3; 1Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea, South, 2Center for Advancing Cancer Therapeutics, Asan Medical Center, seoul, Korea, South, 3Department of Radiation Oncology, Asan Medical Center, Seoul, Korea, South B480/P1095  Nutlin-3 enhances the bortezomib sensitivity of p53-defective cancer cells by induction of paraptosis. D. Lee1,2, I. Kim1,2, M. Seo1,2, M. Kwon1,2, K. Choi1,2; 1Biochemistry, Ajou University, Suwon, United States, 2Department of Biomedical Sciences, Ajou University, Suwon, Korea, South B481/P1096  Studying the Genetic Requirements of Gemcitabine Resistance in Fission Yeast. Z. Kianfard1, S.A. Sabatinos1; 1Chemistry and Biology, Ryerson University, TORONTO, ON B482/P1097  The effect of DNA polymerase eta on cell death in gemcitabine treated human pancreatic tumor cells. D.N. Di Florio1,2, R. Barnes1, K.A. Eckert1; 1Pathology, Gittlen Cancer Research Foundation, Penn State College of Medicine, Hershey, PA, 2Biology, Robert Morris University, Moon, PA B483/P1098  Characterisation of the subpopulations of heterogeneous primary prostate epithelial cell cultures derived from patient tissue. R. Suman1,2, R. Kasprowicz1,2, A.R. Noble3, P. Otoole2, F.M. Frame3, N.J. Maitland3; 1Life Science Applications, Phase Focus Limited, Sheffield, United Kingdom, 2Technology Facility, Imaging and Cytometry, University of York, York, United Kingdom, 3Cancer Research Unit, Department of Biology, University of York, York, United Kingdom B484/P1099  The development of quality control panels for the high-risk human papilomavirus (HR-HPV) detection system. H. Wang1, C. Ma1, Y. Zhou1; 1R & D, AbboMax, Inc, San Jose, CA B485/P1100  Targeted molecular imaging agents (TMIAs) for improved detection of cancers. A. Hanafiah1, A. Embong1, R.L. Walden1, T.C. Anderson1, H.F. Schmitthenner2, I.M. Evans1; 1Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY, 2School of Chemistry and Materials Science, Rochester Institute of Technology, Rochester, NY B486/P1101  The initial study of the correlation between mRNA expression and protein phosphorylation of epidermal growth factor receptor (EGFR) in colorectal and breast cancer cell lines. H. Wang1, C. Ma1, Y. Zhou1; 1R & D, AbboMax, Inc, San Jose, CA B487/P1102  Go or Grow: Loss of Nonmuscle Myosin IIA in Glioblastoma Blocks Tumor Invasion and Enhances Nonmuscle Myosindependent Proliferation. H.S. Picariello1,2, J.F. Crish1, A. Dovas3, J. Lammerding4, P. Canoll3, S.S. Rosenfeld1,2; 1Cancer Biology, Cleveland Clinic, Cleveland, OH, 2Molecular Medicine, Case Western Reserve University, Cleveland, OH, 3Pathology and Cell Biology, Columbia University Medical Center, New York, NY, 4 Meinig School of Biomedical Engineering and Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY

B488/P1103  The role of Cyclin-Dependent Kinase inhibitors on Neuroblastoma cell proliferation, differentiation, and apoptosis. R.R. Swadi1, K. Sampat2, B. Pizer3, P. Losty4, V. Sée5, D. Moss1; 1Cellular and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom, 2Alder Hey Children’s Hospital, Liverpool, United Kingdom, 3Oncology Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom, 4Academic Paediatric Surgery Unit, Division of Child Health, University of Liverpool, Liverpool, United Kingdom, 5Centre for Cell Imaging, University of Liverpool, Liverpool, United Kingdom B489/P1104  Cordycepin Suppresses Angiogenesis through Regulation of FAK and p53 Signaling. Y. Lin1,2, S. Liang1, Y. Lu1, C. Kuo1, J. Liou1; 1Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan, 2Institute of Structural Biology, National Tsing Hua University, Hsinchu, Taiwan B500/P1105  Timing of oocyte death controlled by a TAp63a autofeedback phosphorylation regulatory loop. S. Hong1, E. Suh1; 1Life science, Ewha Womans University, Seoul, Korea, South B501/P1106  Gene regulatory pathways involved in glucocorticoid-evoked apoptosis of human leukemic CEM cells. E.S. Sanchez1, C. Ortega1, R.D. Medh1; 1Biology, California State University, Northridge, Northridge, CA B502/P1107  Hesperetin modulates cell cycle of cancer cells, but does not effect that of normal cells. K. Yoshimura1,2, Y. Ogawa2, M. Kato2, K. Suzuki2, N. Nishida2, C. Tokunaga2, Y. Miyawaki2, Y. Ishihara3, N. Tominaga3, M. Nishina3, S. Watanabe1, K. Nagy4; 1Physiology, Saitama Medical University, Saitama, Japan, 2 Health Sciences, Nihon Institute of Medical Science, Saitama, Japan, 3Medical Center, Saitama Medical University, Saitama, Japan, 4 Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary B503/P1108  BS6 induced apoptosis in human uterine leiomyoma cells. S. Lee1; 1KM Fundamental Research Division, Korea Institute of Oriental Medicine, Daejeon, KS B504/P1109  Hyperactivation of YAP/TAZ oncoproteins promotes mitotic slippage following prolonged mitotic arrest. A.F. Bolgioni1, N.J. Ganem1,2; 1Department of Pharmacology Experimental Therapeutics, Boston University, Boston, MA, 2Department of Medicine, Division of Hematology and Oncology, Boston University, Boston, MA B505/P1110  High Levels of Hemodynamic Shear Stresses Achievable under Exercise Condition Destroy Circulating Tumor Cells in a Microfluidic System. K. Luo1, S. Regmi2, A. Fu2; 1Faculty of Health Sciences, University of Macau, Taipa, Macao, 2School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, Singapore B506/P1111  Allergen-removed Rhus verniciflua Stokes Extract induces Ovarian Cancer Cell Death via JNK Activation. S. Kang1, J. Eunbi1, I. Jang1; 1Division of Bioconvergence, Korea Basic Science Institute, Daejeon, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B507/P1112  In-Vitro Anti-Cancer Actions of Androgens (Androstenedione and Testosterone) Based on Human Melanoma Rescued and Recovered Cell Growth, Adhesion and Migration Functions. T. Hohenbery1, P. Ramaraj1; 1Biochemistry, KCOM/A.T.Still University, Kirksville, MO B508/P1113  Development of Hyaluronic acid-targeted Stigmasterol-Transferrin Nanoparticles for Cancer Therapy. Z. Torres1, Y. Delgado1, K.H. Griebenow1; 1Chemistry, University of Puerto Rico-Rio Piedras campus, San Juan, PR

Oncogenes and Tumor Suppressors 2 B509/P1114  Single-chromosome aneuploidy commonly functions as a tumor suppressor. J. Sheltzer1; 1Cancer Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

B511/P1116  Novel isatin-Schiff base copper (II) complexes as potential p53-activating pro-apoptotic agents. P. Davidovich1, R. Sayarova2, A. Valiullina2, V. Solovyeva2, M. Gomzikova2, A. Smirnov1, A. Rizvanov2, E. Bulatov2; 1St. Petersburg State Institute of Technology, St. Petersburg, Russia, 2Kazan Federal University, Kazan, Russia B512/P1117  The differential RBBP6 (retinoblastoma binding protein 6) expression predicts p53-induced apoptosis in human breast cancer cell lines. L.R. Motadi1; 1Biological Sciences, North-West University, Mafikeng, South Africa B513/P1118  PA28γ expression affects the acquisition of cancer phenotypes. G.S. Melchor1, K.B. Peterson1, H.E. Butterfield1, L.F. Barton1; 1Biology Department, Austin College, Sherman, TX B514/P1119  Inhibition of CRM1 activity by Leptomycin B sensitizes cells to TRAIL and cisplatin induced apoptosis. F. Fabi1, P. Adam1, F. Joncas1, S. Parent1, E. Asselin1; 1Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivieres, QC B515/P1120  Analysis of the RCAN1 gene knockdown in Dex-induced apoptosis using human lymphoblastic leukemia cells. J. Hurtado1, R.D. Medh1; 1Biology, California State University; Northridge, Northridge, CA B516/P1121  Isoform-specific ubiquitination of the RET receptor. M.J. Crupi*1, B.D. Hyndman*1, L.N. Bone2, C.N. Antonescu2, L.M. Mulligan1; 1Pathology and Molecular Medicine, Queen`s University, Kingston, ON, 2Chemistry and Biology, Ryerson University, Toronto, ON

B517/P1122  Cancer-associated Ras/Erk signal misperception can drive hyper-proliferation. L.J. Bugaj1, A. Sabnis2,3, A. Mitchell4, J. Garbarino1, T. Bivona3,5, J.E. Toettcher6, W. Lim1,7,8; 1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 2Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 4Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA, 5Division of Hematology and Oncology, University of California, San Francisco, San Francisco, CA, 6Department of Molecular Biology, Princeton University, Princeton, NJ, 7Center for Systems and Synthetic Biology, University of California, San Francisco, San Francisco, CA, 8Howard Hughes Medical Institute, San Francisco, CA

B525/P1130  Secondary mutations in BRCA-deficient tumors that influence drug resistance mechanisms and can serve as biomarkers in breast tumors. J.S. Davis1; 1Biochemistry & Cancer Biology, Meharry Medical College, Nashville, TN B526/P1131  Bioenergetic Phenotype of RARRES1-Depleted Epithelial Cells. S. Maimouni1, M. Lee2, S.W. Byers1,2; 1Department of Biochemistry and Molecular Cellular Biology, Georgetown University, Washington, DC, 2Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC

B519/P1124  The non-canonical pathways of Transforming Growth Factor β in ovarian carcinoma. L. Catane1, C.G. Trope2, B. Davidson2,3, R. Reich1; 11Institute of Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel, 2The Medical Faculty, University of Oslo, Oslo, Norway, 3Department of Pathology, Norwegian Radium Hospital, Oslo, Norway

B527/P1132  Germline POLG1 variants disrupt mitochondrial function and confer tumorigenic properties. P. Bajpai1, B. Singh1, K.M. Owens2, V. Srinivasasainagendra3, H.K. Tiwari3, K. Singh1,4,5,6,7,8,9; 1Department of Genetics1,, University of Alabama at Birmingham, Birmingham, AL, 2Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY, 3Department of Biostatistics2,, University of Alabama at Birmingham, Birmingham, AL, 4 Department of Pathology3,, University of Alabama at Birmingham, Birmingham, AL, 5Department of Environmental Health3, University of Alabama at Birmingham, Birmingham, AL, 6 Center for Free Radical Biology3,, University of Alabama at Birmingham, Birmingham, AL, 7 Center for Aging3, University of Alabama at Birmingham, Birmingham, AL, 8UAB Comprehensive Cancer Center3, University of Alabama at Birmingham, Birmingham, AL, 9Birmingham Veterans Affairs Medical Center4, Birmingham, AL

B520/P1125  Adenomatous Polyposis Coli regulates tumorigenic phenotypes through C-terminal-mediated cytosolic interactions. A.C. Lesko1,2, G. Davis2, M. Chandra1,2, J.R. Prosperi1,2,3; 1Biological Sciences, University of Notre Dame, Notre Dame, IN, 2Harper Cancer Research Institute, South Bend, IN, 3Biochemistry and Molecular Biology, Indiana University School of Medicine, South Bend, IN

B528/P1133  Polarity protein regulation of epithelial organisation: implications for tissue cohesion and cancer. G. Sandhu1, L. Ona1, I. Tunggal1, L. Fink2, E. Dray3, A. Shewan1; 1SCMB, The University of Queensland, Brisbane, Australia, 2Diamantina Institute, The University of Queensland, Brisbane, Australia, 3 IHBI, Queensland University of Technology, Brisbane, Australia

B521/P1126  Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential. M. Thomas1, M.P. Myers2, P. Massimi1, C. Guarnaccia3, L. Banks1; 1Tumour Virology, ICGEB, Trieste, Italy, 2Protein Networks, ICGEB, Trieste, Italy, 3Biotechnology Development, ICGEB, Trieste, Italy

B529/P1134  Epidermal differentiation is impaired in a 3D culture model of keratinocyte carcinoma. L. Brooks III1, L.A. Ing1, S.T. Arron1; 1Dermatology, University of California, San Francisco, San Francsisco, CA

B518/P1123  Arl11 contributes to macrophage activation and tumor cell apoptosis by regulating ERK1/2 signaling. S.B. Arya1, D. Jagga1, H. Kaur1, A. Tuli1; 1Cell Biology and Immunology, CSIR-Institute of Microbial Technology (IMTECH), Chandigarh, India

B522/P1127  Effects of acid ceramidase overexpression on H295R adrenal carcinoma cells. L.S. Turner1; 1Biology, Francis Marion University, Florence, SC B523/P1128  Profiling changes in response to hypoxia in a four-step cell line model for malignant transformation. F. Danielsson1, L. Åkesson1, M. Skogs1, M. Uhlén1, E. Lundberg1; 1Proteomics, KTH Royal Institute of Technology, Stockholm, Sweden B524/P1129  NSMF mediates psychological stress-induced breast cancer progression. K. Shin1, Y. Lee1, H. Moon2, S. Park1, Y. Seo1, S. Ryu3, P. Suh1; 1School of Life Sciences, UNIST, Ulsan, Korea, South, 2Neuroplasticity and Behavior Unit, Laboratory of Neurosciences, NIA/NIH, Baltimore, MD, 3Division of Molecular and Life Science, POSTECH, Pohang, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B530/P1135  HBx-induced Ca2+ aberrancy in hepatocellular carcinoma. P. Tsai1, Y. Lin1, F. Tsai1,2; 1Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, 2Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

Migration and Metastasis B531/P1136  MenaINV expression, initiated by macrophage-tumor cell contact, regulates invadopodium-dependent tumor cell dissemination during metastasis. C.R. Surve1, M. Weidmann1, J. Pignatelli1, J. Bravo-Cordero2, G.S. Karagiannis1, M.H. Oktay1,3, J.S. Condeelis1; 1Anatomy and Structural Biology, Albert Einstein college of Medicine, Bronx, NY, 2 Medicine, Mount Sinai School of Medicine, New York, NY, 3Pathology, Albert Einstein college of Medicine, Bronx, NY

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B510/P1115  Prion like propagation of p53 amyloid leading to cancer. S. Sengupta1, D. Ghosh1, A. Navalkar1, S. Ghosh1, S. Salot1, S. Das1, R.S. Jacob1, R. Kumar1, N.N. Jha1, S. Sahay1, S. Mehra1, S.K. Ghosh1, S.K. Maji1; 1Bioscience and Bioengineering, Indian Institute of Technology, Mumbai, India

Monday Poster Session

Board No./Presentation No. B532/P1137  How do tumor cell clusters gain access to the systemic circulation? V.L. Silvestri1, A. Wong2, P. Searson2,3, A.J. Ewald1; 1Departments of Cell Biology, Oncology, and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Materials Science and Engineering, and Institute for Nanobiotechnology (INBT), Johns Hopkins University, Baltimore, MD, 3Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD B533/P1138  Hemodynamic Profiles Tune the Arrest and Extravasation of Circulating Tumor Cells. G. Follain1, N. Osmani1, G. Allio1, N. Fekonja1, S. Harlepp2, J.G. Goetz1; 1MN3T, iNSERM U1109, STRASBOURG, France, 2 DON, IPCMS, STRASBOURG, France B534/P1139  3D molecular crowding triggers vascular mimicry through a conserved transcriptional response module. D. Ortiz1, B. Tsui2, T. Goshia1,3, A. Han1, H. Carter2, S.I. Fraley1; 1Bioengineering, University of California San Diego, La Jolla, CA, 2Medicine, University of California San Diego, La Jolla, CA, 3Bioengineering, University of California Merced, Merced, CA B535/P1140  Cancer cell migration: Is 3D spheroid better than 2D. T. Dey1, S. Gayan1; 1Institute of Bioinformatics and Biotechnology, Savitribai Phule Pune University, Pune, India B536/P1141  Genome variation in an osteosarcoma cell line after pore migration. J. Irianto1, Y. Xia1, C.R. Pfeifer1, J. Ji1, C.M. Alvey1, M. Tewari1, R.A. Greenberg2, D.E. Discher1; 1School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, PA, 2Cancer Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA B537/P1142  Senescent tumor cells lead the collective invasion in thyroid cancer. Y. Kim1, T. Park1, J. Kim 2; 1Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, Korea, South, 2Pathology, Ajou University School of Medicine, Suwon, Korea, South B538/P1143  Identifying genomic signatures of rare cancer cells within a heterogeneous collective invasive pack. B. Pedro1,2, J. Konen1,2, E. Summerbell1,2, W. Li2, B. Dwivedi3, J. Kowalski3, P.M. Vertino4, A.I. Marcus2; 1Graduate Program in Cancer Biology, Emory University, Atlanta, GA, 2Hematology and Medical Oncology, Emory University, Atlanta, GA, 3Biostatistics and Bioinformatics, Emory University, Atlanta, GA, 4Radiation Oncology, Emory University, Atlanta, GA B539/P1144 WITHDRAWN B540/P1145  Cell-cell cooperativity modulates proliferation and mitotic defects of phenotypically heterogeneous invading cancer cells. E. Summerbell1,2, J. Konen1,2, A.I. Marcus1; 1Hematology and Medical Oncology, Emory University, Atlanta, GA, 2Graduate Program in Cancer Biology, Emory University, Atlanta, GA B541/P1146  Lysophosphatidic acid induces

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Monday Poster Session

Tumor Microenvironment 2

p-ERK and promotes cell migration in ovarian carcinoma. H. Onalla1, C.G. Trope2, B. Davidson2,3, R. Reich1; 1Institute of Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel, 2The Medical Faculty, University of Oslo, Oslo, Norway, 3Department of Pathology, Norwegian Radium Hospital, Oslo, Norway

B549/P1154  Carcinoma-associated fibroblasts lead cancer cell invasion through fibronectin assembly. Y. Atieh1, A.G. Clark1, S. Richon1, C. Grass1, P. Maiuri1, B. Gurchenkov1, D.M. Vignjevic1; 1UMR144, Institut Curie, Paris, France

B542/P1147  PPAP2B mediates self-generation of LPA gradients by melanoma cells. O.D. Susanto1, Y.W. Koh1, N. Morrice1, N. van den Broek1, S. Tumanov1,2, P.A. Thomason1, M. Nielson1, L. Tweedy1, A. Muinonen-Martin3,4, J. Kamphorst1,2, G. Mackay1, R.H. Insall1; 1Cell Migration and Invasion, Beatson Institute for Cancer Research, Glasgow, United Kingdom, 2 University of Glasgow, Institute for Cancer Sciences, Glasgow, United Kingdom, 3Melanoma Institute, Leeds Cancer Centre, Leeds, United Kingdom, 4York Teaching Hospital NHS Foundation Trust, York, United Kingdom

B550/P1155  Increased contractility and traction forces exerted by cancer-associated fibroblasts align fibronectin to direct cancer cell migration. B. Erdogan1, M. Ao1, B. Brewer2, L. White1, O.E. Franco3,4, S.W. Hayward3,4,5, D. Li2, D.J. Webb1,3; 1Biological Sciences, Vanderbilt University, Nashville, TN, 2 Mechanical Engineering, Vanderbilt University, Nashville, TN, 3Cancer Biology, Vanderbilt University, Nashville, TN, 4Surgery, NorthShore University Healthsystem, Evanston, IL, 5Urologic Surgery, Vanderbilt University, Nashville, TN

B543/P1148  Effect of cAMP on modulating the migration, proliferation and invasion of Neuroblastoma cells. R.F. Inuwa1, J.M. Quayle1, D. Moss1; 1Cellular and Molecular Physiology, Liverpool University, Liverpool, United Kingdom

B551/P1156  Mesenchymal stem cells respond to matrix stiffness to promote mammary carcinoma proliferation via prosaposin secretion. S. Ishihara1, D.R. Inman1, W. Li2, S.M. Ponik1, P.J. Keely1; 1Department of Cell and Regenerative Biology, University of WisconsinMadison, Madison, WI, 2Departments of Orthopedics and Rehabilitation Biomedical Engineering, University of Wisconsin-Madison, Madison, WI

B544/P1149  Role of progesterone and protease ADAMTS 1 on migration and invasion of ovarian tumor cells. M.D. Lima1, S.V. Silva1, V.M. Freitas1; 1Department of Cell and Developmental Biology, University of Sao Paulo, Sao Paulo, Brazil B545/P1150  Anillin Regulates Breast Cancer Cell Migration and Metastasis. D. Wang1, J. Koblinski2, A.I. Ivanov1; 1Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, 2Department of Pathology, Virginia Commonwealth University, Richmond, VA B546/P1151  Cell cycle dependent front polarized cell migration requires Aurora Kinase A. T. Chu1, L. Zhou2, J. Won3, P. Mohan1, O. Nemirovsky1, A. Fotovati1, T. Nielsen3, N. Pante2, C.A. Maxwell1; 1Pediatrics, The University of British Columbia, Vancouver, BC, 2 Zoology, The University of British Columbia, Vancouver, BC, 3Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC B547/P1152  Transforming growth factorbeta1 induces epithelial to mesenchymal transition through down-regulation of Dickkopf-1 in human A549 lung cancer cells. Y. CHOI1, B. Kim1; 1Department of Biochemistry, Kangwon National University, Chuncheon, Korea B548/P1153  Collective Epithelial-based Metastases in Colorectal Carcinoma Patients. O. Zajac1,2,3, R. Joel1,2,3, F. Libanje1,2,3, C. Lefebvre1,3, D.I. Sabino4, I. Martins3, P. Roy2, J. Scoazec5, C. Eveno6, M. Pocard6, J. Perfettini3, D. Elias7, P. Dartigues5, D. Goere7, F. JAULIN1,2,3; 1INSERM U-981, Villejuif, France, 2 CNRS UMR-8126, Villejuif, France, 3Gustave Roussy Institute, Villejuif, France, 4Pasteur Institute, Paris, France, 5Pathology department, Gustave Roussy hospital, Villejuif, France, 6 U-965, Lariboisiere Hospital, Paris, France, 7 Surgery, Gustave Roussy hospital, Villejuif, France

B552/P1157  RTK signaling in response to extracellular stiffness at the single molecule level. D. Thakar1, S. Low-Nam2,3, J.T. Groves2,3, V.M. Weaver1,4,5,6; 1Center for Bioengineering and Tissue Regeneration, Department of Surgery,, University of California San Francisco (UCSF), San Francisco, CA, 2 Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 3 Department of Chemistry, University of California, Berkeley, Berkeley, CA, 4Department of Anatomy, and Department of Bioengineering and Therapeutic Sciences, University of California San Francisco (UCSF), San Francisco, CA, 5 Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco (UCSF), San Francisco, CA, 6UCSF Helen Diller Comprehensive Cancer Center, University of California San Francisco (UCSF), San Francisco, CA B553/P1158  A role for fibrosis in promoting pro-tumor immune response in breast cancer. O. Maller1, L. Cassereau1, A. Drain 1, B. Ruffell2, I. Acerbi1, M. Broz3, J. Munson4, M. Swartz5, M.F. Krummel3, L.M. Coussens6, V.M. Weaver1; 1Department of Surgery, University of California San Francisco, San Francisco, CA, 2 Moffitt Cancer Center, Tampa, FL, 3Department of Pathology, University of California San Francisco, San Francisco, CA, 4Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 5Institute for Molecular Engineering, University of Chicago, Chicago, IL, 6Department of Cell Developmental Biology, Oregon Health Sciences University, Portland, OR B554/P1159  Cancer-Associated Fibroblast Differentiation by Downregulation of SPIN90 Promotes Breast Cancer Progression. E. You1, Y. Huh2, A. Kwon2, D. Kim1, P. Ko1, J. Jeong1, S. Oh1, S. Keum1, W. Song2, S. Rhee1; 1Life science, Chung-Ang University, Seoul, Korea, 2Life science, Gwangju Institute of Science and Technology, Gwangju, Korea

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B555/P1160  NCoR2 mediates death-resistance and mechano-regulation of glioblastoma multiforme. S. Kaushik1, K.K. Tsai2, J.M. Barnes1, J.J. Phillips3,4, V.M. Weaver1,5,6,7; 1Center for Bioengineering and Tissue Regeneration, Department of Surgery, UCSF, San Francisco, CA, 2Laboratories for Tumor Aggressiveness and Stemness, National Institute of Cancer Research, Tainan, Taiwan, 3Department of Neurosurgery, UCSF, San Francisco, CA, 4Department of Pathology, UCSF, San Francisco, CA, 5Helen Diller Comprehensive Cancer Center, UCSF, San Francisco, CA, 6 Department of Anatomy, and Department of Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA, 7Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA

B557/P1162  Transmembrane 4 L six family member 5 (TM4SF5) regulates CD44 alternative splicing for cell survival. J. Kim1; 1Pharmacy, Seoul National University, Seoul, Korea, South B558/P1163  Tumor Microenvironment Regulation of MenaINV Expression In Breast cancer. N. Rohani Larijani1, M.N. Moufarrej2, Y.L. Khodor3, C. Kroeger4, M. Oudin1, F.B. Gertler1,3; 1Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, 2Department of Biological Engineering, MIT, Cambridge, MA, 3 Department of Biology, MIT, Cambridge, MA, 4 Whitehead Institute for Biomedical Research, MIT, Cambridge, MA B559/P1164  ADAMTS-1 Impairs HGF-Induced Proliferation and Migration on HT1080 Cells. H. Noriega Guerra1, M.C. Cruz2, P.R. Lara Ribeiro1, V.M. Freitas1; 1Department of Cell and Developmental Biology, Biomedical Sciences Institute - USP, São Paulo, Brazil, 2Center of Facilities and Support Research, Biomedical Sciences Institute - USP, São Paulo, Brazil B560/P1165  Role of ADAMTS-1 in the nucleus of normal-like and tumoral human breast cells. S.V. Silva1, V.M. Freitas1, M.D. Lima1; 1Biologia Celular e do Desenvolvimento, Universidade de São Paulo -USP, São Paulo, Brazil

B561/P1166  Role of linoleic acid on the response induced by insulin in MDA-MB-231 breast cancer cells. C. Rodríguez-Monterrosas1, A. Ordonez1, C. Gonzalez-Reyes1, E.P. Salazar1; 1Biologia Celular, Cinvestav-IPN, Mexico, Mexico B562/P1167  The role of myoepithelial cells in suppressing Twist1-induced cell dissemination. K. Sirka1, E.R. Shamir1,2, A.J. Ewald1; 1Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Pathology, USCF School of Medicine, San Francisco, CA B563/P1168  Calcipotriol treatment enhances wound closure and antimicrobial defense in recessive dystrophic epidermolysis bullosa in vitro while inhibiting proliferation and clonogenicity of RDEB cancer cells. B. Tockner1, C. Scharler2, C. Hüttner1, A. Zurl3, D. Strunk2, J.W. Bauer4, J. Reichelt1, R. Lang4, C. Gruber1, J. Pinon Hofbauer 1; 1Department of Dermatology, University Hospital of the Paracelsus Medical University, EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Salzburg, Austria, 2Core Facility for Flow Cytometry, Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCITReCS), PMU Salzburg, Experimental Clinical Cell Therapy Institute, Salzburg, Austria, 3Research program for Ophthalmology and Glaucoma Research, Paracelsus Medical University, University Clinic of Ophthalmology and Optometry, Salzburg, Austria, 4University Hospital Salzburg, Paracelsus Medical University Salzburg, Department of Dermatology, Salzburg, Austria B564/P1169  Alpha1-antitrypsin-derived Cterminal peptide activity at subnanomolar to micromolar concentrations in human cell lines: a mitogen and a metabolism activator. A.A. Maslakova1, O.S. Sokolova1, I.V. Orlovsky2; 1Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia, 2 A.N. Belozersky Research Institute of Physical and Chemical Biology, Lomonosov Moscow State University, Moscow, Russia B565/P1170  Lactate Accumulated by Hypoxic Cells Induces HIF-1a Oscillations through a Quorum Autophagy Response. .. Kshitiz1,2, J. Afzal2, H. Chang1,2, R. Goyal1, Y. Suhail2, P. SunSun2, M. Hubbi2, C. Dang3, A. Levchenko1,2; 1Biomedical Engineering, Yale University, West Haven, CT, 2Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, 3Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA B566/P1171  CD82 expression promotes acute myeloid leukemia niche adhesion and chemoresistance. M. Floren1, C.M. Termini1, K.D. Marjon2, J.M. Gillette1; 1Pathology, University of New Mexico, Albuquerque, NM, 2Stanford Medicine, Stanford University, Palo Alto, CA B567/P1172  Differential expression of spindle assembly checkpoint (SAC) genes in 3D cell culture models of breast cancer cell lines. M. Moenk1, S. Liu1; 1Biological Sciences, University of Toledo, Toledo, OH

Gene Structure and Transcription B900/P1174  Cryo-EM visualization of promoter binding by the human general transcription factor TFIID. R.K. Louder1, A. Patel1, Y. He2,3, J. Fang4, E. Nogales2,4,5,6; 1Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, 2Molecular Biophysics and Integrative Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 3 Northwestern University, Department of Molecular Biosciences, Evanston, IL, 4Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, 5QB3 Institute, University of California, Berkeley, Berkeley, CA, 6Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA B901/P1175  Genome wide view of how p53 dynamics regulate gene expression. A. Hafner1, J. Stewart-Ornstein1, G. Lahav1; 1Department of Systems Biology, Harvard Medical School, Boston, MA B902/P1176  Regulation of estrogen-responsive genes in single human cells. J. Rodriguez1, C.C. Chow2, D.R. Larson1; 1Laboratory of Receptor Biology Gene Expression, National Cancer Institute, Bethesda, MD, 2 Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD B903/P1177  Analysis of the exon-intron structure of β-tubulin genes in different plant species. R.Y. Blume1,2, A.N. Rabokon3, A.Y. Demkovich3, Y.V. Pirko3, A.I. Yemets2; 1Institute of Biology, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, 2Genomics and Molecular Biotechnology, Institute of Food Biotechnology and Genomics, Kiev, Ukraine, 3 Population Genetics, Institute of Food Biotechnology and Genomics, Kiev, Ukraine B904/P1178  Cytokine-induced autophagy promotes sustained expression of VCAM-1 and a subset of pro-inflammatory genes with similar promoter binding motifs. L. Chu1, Y. Hsueh2, K.K. Wu1,2; 1Metabolomic Medicine Research Center, China Medical University Hospital, Taichung, Taiwan, 2Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan B905/P1179  The Histone Variant H2A.Z Promotes Splicing of Weak Introns. K.E. Nissen1, C.M. Homer1, C.J. Ryan2, J.J. Lipp1, M. Shales3, N. Krogan3,4,5, K. Patrick6, C. Guthrie1; 1Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, 2 Systems Biology Ireland, University College Dublin, Belfield, Republic of Ireland, 3Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 4QB3, California Institute for Quantitative Biosciences, San Francisco, CA, 5J. David Gladstone Institutes, San Francisco, CA, 6Microbial Pathogenesis and Immunology, Texas AM Health Science Center, Bryan, TX

B568/P1173  Molecular profiling of tumor microenvironment for biomarker discovery. A. Komarov1, A.A. Chenchik1, M. Makhanov1, P. Diehl1, C. Frangou1; 1Cellecta, Inc., Mountain View, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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MONDAY

B556/P1161  A three-dimensional extracellular matrix enhances cell viability by increasing negative membrane curvature to stimulate Arf6/Rac/Pak activity. F. Kai1, G. Ou1, J. Friedland1, C. Frantz1, R. Tourdot2, W. Guo3, C.S. Chen4, R. Radhakrishnan2,5, A. Long6, S. Dumont6, V.M. Weaver1,7,8,9,10; 1Surgery, University of California, San Francisco, San Francisco, CA, 2Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Philadelphia, PA, 3Biology, University of Pennsylvania, Philadelphia, Philadelphia, PA, 4Biomedical Engineering, Boston University, Boston, MA, 5Bioengineering, University of Pennsylvania, Philadelphia, Philadelphia, PA, 6 Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 7Anatomy, University of California, San Francisco, San Francisco, CA, 8 Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, 9Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, 10Helen Diller Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA

Monday Poster Session

Board No./Presentation No. B906/P1180  Conformational dynamics of Cas9 during DNA binding. Y.S. Dagdas1, J.S. Chen2, S.H. Sternberg3, J.A. Doudna2,3,4,5, A. Yildiz2,6; 1Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, 2Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 3 Department of Chemistry, University of California, Berkeley, Berkeley, CA, 4Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, 5Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 6Department of Physics, University of California, Berkeley, Berkeley, CA B907/P1181  Estrogen response element in somatolactin beta promoter its involved in differential response to estrogen in carp pituitary. G.E. Valenzuela 1, F. Stolzenbach1, M. Vega1, J.E. Figueroa1, M. Muller2, G. Kausel1; 1Instituto de Bioquímica y Microbiología, Universidad Austral de Chile, Valdivia, Chile, 2GIGA Center, Liege University, Liege, Belgium B908/P1182  Defining transcriptional networks that control molting in C. elegans and Brugia malayi. J.D. Ward1; 1Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA B909/P1183  Synergism of Dam, MutH, and MutS of Methylation-Directed Mismatch Repair In Escherichia Coli. C. Hu1, Y. Yang1, H. Sun1; 1Biological Sciences, Emporia State University, Emporia, KS B910/P1184  A polyglutamine domain enables transcriptional reprogramming in response to a transient pH change. I. Gutiérrez1,2, S. Alberti3, T. Franzmann3, D. Fenyo2, X. Wang2, L.J. Holt2; 1MCB, University of California, Berkeley, Berkeley, CA, 2ISG, New York University, New York, NY, 3Molecular Cell Biology and Genetics, Max Plank institute, Dresden, Germany B911/P1185  Transcriptional dynamics and the regulation of chromatin accessibility in Drosophila embryonic development. E.C. Eck1, M. Kazemzadeh-Atoufi2, H.G. Garcia3,4; 1Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, 2Department of Physics and Astronomy, University of North Carolina, Chapel Hill, Chapel Hill, NC, 3Department of Physics, University of California, Berkeley, Berkeley, CA, 4Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA B912/P1186  Nitrous acid-mediated mutagenic activation of 2,4,6-tribromophenol (TBP). T.J. Schrader1, A. Wan1; 1Regulatory Toxicology Research Division, Health Canada, Ottawa, ON B913/P1187  SLC6A4 promoter sequence heterogeneity in a mixed military cohort of control and post-traumatic stress disorder patients. S. Hune1, H. Xia1, S.L. Hall1, M.Y. Caballero1, S. Valtier1, G.J. Chaudry1, A.M. Willis2; 1Center for Advanced Molecular Detection, Science Technology, 59 Medical Wing, JBSALackland, TX, 2Neurology, San Antonio Military Medical Center, San Antonio, TX

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Monday Poster Session B914/P1188  The Fasciculation and Elongation Zeta-1 (FEZ1) protein as an interactor of Retinoic Acid receptor and inducer of Hoxb4 gene. M.B. Teixeira1, A.C. Figueira2, L. Wei3, J. Kobarg1; 1Department of Biochemistry and Tissue Biology, University of Campinas, Campinas, Brazil, 2Brazilian Biosciences National Laboratory, Center for Research in Energy and Materials, Campinas, Brazil, 3Pharmacology Department, University of Minnesota Medical School, Minneapolis, MN B915/P1189  Novel imaging tools reveal dynamic processing of environmental information in plant cells. J.S. Alamos1, H.G. Garcia2,3, K. Niyogi1; 1Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA, 2Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, 3 Department of Physics, University of California, Berkeley, Berkeley, CA

Post-Transcription Gene Regulation B916/P1190  Alternative Polyadenylation of RECK Regulates Cell Migration and Invasion. H. Lee1, M. Mithun2,3, D.C. Corney2,3,4, E.L. Johnson4, O. Bosompra3, H.A. Coller1,2,3; 1Molecular Biology Interdepartmental Doctoral Program, University of California, Los Angeles, Los Angeles, CA, 2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 3Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, 4 Department of Molecular Biology, Princeton University, Princeton, NJ B917/P1191  Protein expression dynamics in MAPK response network vary due to polymorphic translation rate modifiers. D.A. Pollard1, C. Asamoto1, A. Abendroth1, H. Rahnamoun2, S.A. Rifkin2; 1Biology, Western Washington University, Bellingham, WA, 2Biological Sciences, University of California San Diego, San Diego, CA B918/P1192  Mechanisms toward the toleration of whole-chromosome aneuploidy. K.E. Larrimore1, N.S. Barattin-Voynova1, D.W. Reid2, N. Bouzelmat1, D. Ng1,3; 1Cell Stress and Homeostasis, Temasek Life Sciences Laboratory, Singapore, Singapore, 2Duke-NUS Graduate Medical School, Singapore, Singapore, 3 Department of Biological Sciences, National University of Singapore, Singapore, Singapore B919/P1193  Isoform diversity of Rbfox family proteins. J. Parilla1, M.E. Elshazzly1, K. Vaidya1, R.S. Adelstein1, S. Kawamoto1; 1NHLBI, National Institutes of Health, Bethesda, MD B920/P1194  Mechanism of regulation of the transcription factor ATF4 during therapeutic stresses. P. Adjibade1,2, V. St Sauveur1,2, E. Khandjian3,4, R. Mazroui1,2; 1Department of Molecular Biology, Medical Biochemistry, and Pathology, CHU de Quebec Research Center, Laval University, Quebec, QC, 2Laval University Cancer Research Center, Quebec, QC, 3Institut universitaire en santé mentale de Québec, Quebec, QC, 4Department of psychiatry and neurosciences, Faculty of Medicine, Laval University, Quebec, QC

B921/P1195  Identification and characterization of alternative open reading frames in budding yeast meiosis. A.R. Eisenberg1, I. Hollerer1, P. Diamond1, G.A. Brar1; 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA B922/P1196  Rescue of mutation-induced exon 7 skipping in human Cathepsin A by using modified U1 small nuclear RNA. N. Yamazaki1, Y. Shinohara1,2, K. Itoh1, N. Minakawa1, Y. Takiguchi1; 1Faculty of Pharmaceutical Sciences, Tokushima University, Tokushima, Japan, 2Institute for Genome Research, Tokushima University, Tokushima, Japan B923/P1197  Functional dissection of proliferating-cell nuclear antigens (1 and 2) in human malarial parasite Plasmodium falciparum: possible involvement in DNA replication and DNA damage response. K. BANU1, P. Mitra1, S.K. Dhar1; 1Special Center for Molecular Medicine, Jawaharlal Nehru University, New Delhi, IN B924/P1198  Conserved ribosome heterogeneity in stem cells and yeast. N. Slavov1,2,3, A. van Oudenaarden4; 1Biology, Northeastern University, Boston, MA, 2Bioengineering, Northeastern University, Boston, MA, 3Proteomics, Broad Institute, Boston, MA, 4Developmental Biology and Stem Cell Research, Hubrecht Institute, Utrecht, Netherlands B925/P1199  RNA methylation and demethylation have effect on somatic cell reprogramming. Y. Wu1, B. Peng1, X. He1, C. Wan1, S. Gao1; 1School of Life Sciences and Technology, Tongji University, Shanghai, China B926/P1200  A Genetic Interaction Between DED1 and HAT1 in Saccharomyces cerevisiae Suggests a Role for Hat1p in mRNA storage. A. Kindsfather1, A. Winters1, N. Rothbard1, S. Robins1, L. Fronek1, A.K. Hilliker1; 1Biology, University of Richmond, Richmond, VA B927/P1201  Identifying Factors that Regulate Translation by Selecting for Loss-of-Function Suppressors of DED1. T. Drewes Tartarotti1, A. Winters1, J. Bowman2, G. Whitworth2, A.K. Hilliker1; 1Biology, University of Richmond, Richmond, VA, 2Biology, Washington and Lee University, Lexington, VA B928/P1202  Screening for conditional mutations in MTR4, an RNA helicase component of the nuclear exosome. H.V. Pingali1, E. Abrash2, A.K. Hilliker1; 1Biology, University of Richmond, Richmond, VA, 2Biology, Kenyon College, Gambier, OH B929/P1203  Investigating the effect of arginine methylation in Ded1, an RNA ATPase that promotes translation. N. D’Ambrosio1, A. D’Alessandro1, J. DiBello1, E. Provencher1, A.K. Hilliker1; 1Biology, University of Richmond, Richmond, VA B930/P1204  PPARγ induces microRNA-143 expression in adipocytes by GPR-120 dependent pathway. I. Bae1, S. Kim1; 1Department of Biology, Kyung Hee University, Seoul, Korea, South B931/P1205  Translational Regulation of DDX3/Ded1 Medulloblastoma Mutations. N.P. Brown1, T.A. Bolger1; 1Molecular and Cellular Biology, University of Arizona, Tucson, AZ

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B932/P1206  Activation of the translation initiation factor eIF2B enhances cognition. A. Anand1,2, J.C. Tsai1,2, P. Walter1,2; 1Biochemistry Biophysics, University of California, San Francisco, San Francisco, CA, 2Howard Hughes Medical Institute, San Francisco, CA

The Nuclear Envelope and Nuclear Pore Complexes 2 B934/P1207  Nup98/96 promotes assembly of the nuclear lamina by regulating Lamin B1 expression. J.M. Kaneshiro1, A. Buchwalter1, M.W. Hetzer1; 1Molecular and Cell Biology Laboratory, Salk Institute for Biological Sciences, La Jolla, CA B935/P1208  Determining the order of nucleoporin recruitment during Nuclear Pore Complex Assembly. D. Thaller1, P. Colombi1, P. Lusk1; 1Cell Biology, Yale University, New Haven, CT

B937/P1210  A new strategy for studying nuclear pore proteins in mitosis. V. Aksenova1, A. Arnaoutov1, A. Smith1, M. Dasso1; 1Section on Cell Cycle Regulation, National Institute of Child Health and Human Development, Bethesda, MD B938/P1211  Chm7 and Heh1 form a nuclear envelope subdomain that seals defective nuclear pore complexes. D. Thaller1, B. Webster1, J. Jaeger1, S. Borah1, S. Ochmann1, P. Lusk1; 1Cell Biology, Yale School of Medicine, New Haven, CT B939/P1212  Nuclear pore complex protein NPP-2 regulates cell cycle duration in early Caenorhabditis elegans embryos. C. Zheng1, L. Jiang1, Y. Tse1; 1Department of Biology, Southern University of Science and Technology, Shenzhen, China B940/P1213  The assembly and function of the Annulate Lamellae pore complexes in Xenopus Egg extract and cultured mammalian cells. L.Q. Lu1, H. REN1, L. Guo1, Q. Jiang1, P.R. Clarke2, C. Zhang1; 1College of Life Sciences, Peking University, Beijing, China, 2 Ninewells Hospital And Medical School, University of Dundee, Dundee, United Kingdom B941/P1214  Adaptive evolution to the deletion of essential genes. G. Liu1,2, J. Yong1, M. Yurieva3, S. Kandhadayar Gopalan3, L.Z. Jaron1, J.S. Lim1, M. Poidinger3, G.D. Wright1, F. Zolezzi3, H. Choi4, N. Pavelka3, G.I. Rancati1; 1Institute of medical biology, Agency for Science, Technology and Research, Singapore, Singapore, 2School of biological science, Nanyang Technological University, Singapore, Singapore, 3Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore, 4Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore

B942/P1215  Characterizing Nuclear Pore Complex Remodeling during Meiosis in Budding Yeast. G.A. King1, E.M. Sawyer1, K.L. McDonald2, E. Ünal1; 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Electron Microscope Laboratory, University of California, Berkeley, Berkeley, CA B943/P1216  Membrane binding of Nup155 is important for nuclear pore complex reassembly at the end of mitosis. P. De Magistris1, W. Antonin1; 1Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany B944/P1217  Systematic identification of nuclear sizing factors by high-throughput imaging-based siRNA screening. P. Jevtic1, A.C. Schibler2, G. Pegoraro3, T. Misteli2, D.L. Levy1; 1Molecular Biology, University of Wyoming, Laramie, WY, 2National Cancer Institute, National Institutes of Health, Bethesda, MD, 3 High Throughput Imaging Facility (HiTIF), National Cancer Institute, National Institutes of Health, Bethesda, MD B945/P1218  Nucleoporin TPR is a negative regulator of NPC number. A. McCloskey1, A. Ibarra1, M. Shokhirev2, M.W. Hetzer1; 1Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, 2The Razavi Newman Integrative Genomics and Bioinformatics Core Facility, The Salk Institute for Biological Studies, La Jolla, CA B946/P1219  Opposing roles for LINC complexes in the regulation of the small GTPase RhoA. K. Thakar1, C.W. Carroll1, C. May1; 1Cell Biology, Yale University School of Medicine, New Haven, CT B947/P1220  Ultradonut topology of the nuclear envelope. M. Torbati1, T.P. Lele2, A. Agrawal1; 1Mechanical Engineering, University of Houston, Houston, TX, 2Department of Chemical Engineering, University of Florida, Gainesville, FL B948/P1221  Loss of emerin results in attenuated ERK1/2 activation and impaired MRTF-A translocation. T.J. Kirby1, R. Lin1, P. Isermann1, J. Lammerding1; 1Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY

Nuclear Bodies and Dynamics B949/P1222  The Drosophila neuroblast: a model system for human ribosomopathies. S.S. Baral1, M.E. Lieux1, P.J. DiMario1; 1Biological Sciences, Louisiana State University, Baton Rouge, LA B950/P1223  Molecular and ultra-structural phenotypes associated with the Nopp140 gene deletion in Drosophila melanogaster. A.A. James1, S.S. Baral2, D. Odenheimer2, H.S. Raje2, Y. Wang2, P.J. DiMario2; 1Department of Genetics, Yale School of Medicine, New Haven, CT, 2Biological Sciences, Louisiana State University, Baton Rouge, LA B951/P1224  In vivo formation of vacuolated multi-phase compartments lacking membranes. B. Schmidt1, R. Rohatgi1,2; 1Biochemistry, Stanford University, Stanford, CA, 2 Medicine, Stanford University, Stanford, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B952/P1225  Structure and dynamics of the Polycomb body. J. Smigova1, P. Juda1, O. Raska1, E. Bartova1,2, I. Raska1; 1Institute of Cellular Biology and Pathology, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic, 2Institute of Biophysics of the CAS, v.v.i., Brno, Czech Republic B953/P1226  Quantitative fluorescence correlation spectroscopy on DNA in living cells. C. Hodges1, R.P. Kafle1, J.C. Meiners1; 1LSA Biophysics, University of Michigan, Ann Arbor, MI B954/P1227  Large-scale spatial mapping of the nuclear human proteome. L. Åkesson1, C. Stadler1, D.P. Sullivan1, M. Wiking1, J. Krijgsveld 2, M. Uhlén3, E. Lundberg1; 1Department of Proteomics, Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden, 2Proteomics of Stem Cells and Cancer, DKFZ - Deutsches Krebsforschungszentrum, Heidelberg, Germany, 3Department of Proteomics, KTH - Royal Institute of Technology, Stockholm, Sweden B955/P1228  Nuclear constriction segregates mobile nuclear proteins away from chromatin. C.R. Pfeifer1,2,3, J. Irianto1,2, R.R. Bennett1,3, Y. Xia1,2, I.L. Ivanovska1,2, A.J. Liu1,3, R.A. Greenberg1,4, D.E. Discher1,2,3; 1Physical Sciences Oncology Center at Penn, University of Pennsylvania, Philadelphia, PA, 2Molecular Cell Biophysics Lab, University of Pennsylvania, Philadelphia, PA, 3Department of Physics Astronomy, University of Pennsylvania, Philadelphia, PA, 4Cancer Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA B956/P1229  Association of ZC3H8 with nuclear bodies and its role in promoting tumor cell behavior in vitro and in vivo. J.A. Schmidt1, K.G. Danielson1, J.L. Swiatek1, E.R. Duffner1, J.E. Knepper1; 1Biology, Villanova University, Villanova, PA B957/P1230  Extracellular traps in vitro and co-stimulatory molecules in human leukocytes with positive serology for Chagas disease. F.M. Rodriguez1, A.H. Vargas2, C.L. Carabajal-Miotti2, N.E. Gonzalez-Silva2, S. Ruiz de Frattari2, I.T. Novak1; 1Institute of Cell Biology. Faculty of Medicine, National University of Cordoba,, Cordoba, Argentina, 2Institute of Hematology and Hemotherapy, National University of Cordoba,, Cordoba, Argentina B958/P1231  Role of β-Dystroglycan in the nucleolus. A.M. Sandoval1, P.M. Azuara1, B. Cisneros-Vega1; 1Genetics and molecular biology, CINVESTAV, Mexico City, Mexico B959/P1232  Redundant GA-binding early transcription factors regulate the Drosophila histone locus body. L.E. Rieder1, K. Boltz2, B. Duronio2, E.N. Larschan1; 1Molecular and Cellular Biology, Brown University, Providence, RI, 2Genetics and Molecular Biology, University of North Carolina Chapel Hill, Chapel Hill, NC B960/P1233  G196 epitope tag system: a novel monoclonal antibody, G196, recognizes the small, soluble peptide DLVPR with high affinity. T. Urano1; 1Department of Biochemistry, Shimane University School of Medicine, Izumo, Japan

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MONDAY

B936/P1209  The nuclear pore complex protein NupA is required for normal localization of the mRNA export factor Gle1 in Aspergillus nidulans. L. Abdurehman1, S. Suresh1, S. Osmani1; 1Molecular Genetics, The Ohio State University, Columbus, OH

Monday Poster Session

Board No./Presentation No. B961/P1234  Analysis of compact chromatin in situ by atomic force microscopy. L.F. Jimenez-Garcia1, G. Alvarez-Hernandez1, A. Perez-Torres2, R. Lara-Martínez1, L.T. Agredano1, D. Pineda-Vázquez1, M.L. SeguraValdez1; 1Cell Biology, Faculty of Sciences, UNAM, Mexico City, Mexico, 2Cell and Tissue Biology, Faculty of Medicine, UNAM, Mexico City, Mexico B962/P1235  Nuclear morphology determines the response of cancer cells to anticancer drugs. F. Atrian Afyani1, C. Duffey1, M. Ochoa2, B. Ziaie2,3, S.A. Lelievre1,2,3; 1Basic Medical Sciences, Purdue University, West Lafayette, IN, 2Birck Nanotechnology Center, Purdue University, West Lafayette, IN, 3Purdue Center for Cancer Research, Purdue University, West Lafayette, United States B963/P1236  NuMA controls 53BP1 dynamics and function in DNA double-strand break repair. J. Liu1, N. Salvador Moreno2, L. Parker3, K. Haas4, S.A. Lelievre5, P. Vidi2; 1Nanoscience and Nanoengineering, South Dakota School of Mines, Rapid City, SD, 2Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, IN, 3Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Saint Paul, MN, 4Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC, 5Department of Basic Medical Sciences, Purdue University, West Lafayette, IN B964/P1237  Modeling control of cellular body composition and the implications on function. W. Peeples1, M.K. Rosen1; 1Biophysics, UT Southwestern Medical Center, Dallas, TX B965/P1238  XRCC1 is recruited to singlestrand DNA breaks in regions of replication as a distinct PML-like body. M.M. Kordon1, A. Szczurek1,2, O. Szelest1, J. Dobrucki1; 1Department of Cell Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, 2Super-Resolution Microscopy Group, Institute of Molecular Biology, Mainz, Germany B966/P1239  Cytoskeletal dynamics influence the nuclear shape in human neutrophils. A. Hadjitheodorou1, C. Chan2, J.A. Theriot2; 1Bioengineering, Stanford University, Stanford, CA, 2 Biochemistry, Stanford University School of Medicine, Stanford, CA B967/P1240  Topoisomerase I and RNase H1 are both involved in suppressing R-loops formation during the transcription of rRNA in mammalian cells. W. Shen1, C.L. De Hoyos1, X. Liang1, S.T. Crooke1; 1Core Antisense Research, IONIS Pharmaceuticals, Inc., Carlsbad, CA

Endocytic Trafficking 2 B969/P1241  Yeast Membrane Lipid Imbalance Leads to Trafficking Defects toward the Golgi. S.E. Woodman1, J.L. Conover2, C. Trousdale3, K. Kim1; 1Biology, Missouri State University, Springfield, MO, 2Genetics and Genomics, Iowa State University, Ames, IA, 3 Anesthesiology, Washington University, St. Louis, MO

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Monday Poster Session B970/P1242  Molecular Mechanisms of Sorting Nexin 16. S. Wang1, A.A. Rodal1; 1Biology Department, Brandeis University, Waltham, MA B971/P1243  The interaction of PIPKI gamma with AP2 regulates spatial and temporal focal adhesion dynamics in cells. A.M. Lakoduk1, Z. Kadlecova1, S.J. Han1,2, S.L. Schmid1; 1Cell Biology, UT Southwestern Medical Center, Dallas, TX, 2Bioinformatics, UT Southwestern Medical Center, Dallas, TX B972/P1244  Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 modulates Endocytic Cargo Transport Pathways. K. Ganti1, P. Massimi2, J. Manzo-Merino3, V. Tomaic2,4, D.C. Pim2, M. Playford5, M. Lizano3, S. Roberts6, C. Kranjec7, J. Doorbar7, L. Banks2; 1National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 2Tumour Virology, ICGEB, Trieste, Italy, 3 Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico. Col. Seccion XVI, Unidad de Investigacion Biomedica en Cancer, Instituto Nacional de Cancerologia, Tlalpan, Mexico, 4Rudjer Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia, 5National Heart, Blood and Lung Institute, NIH, Bethesda, MD, 6Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom, 7 Department of Pathology, University of Cambridge, Cambridge, United Kingdom B973/P1245  The dynamic control of GSK3β localization and function via PI3K-AktmTOR signaling and endomembrane traffic. S. Bautista1, C.N. Antonescu1; 1Chemistry and Biology, Ryerson University, Toronto, ON B974/P1246  The adaptor protein APPL1 regulates cancer cell migration through α5β1 trafficking and Rac activation. N. Diggins1, D.J. Webb1,2,3; 1Biological Sciences, Vanderbilt University, Nashville, TN, 2Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN, 3Cancer Biology, Vanderbilt University, Nashville, TN B975/P1247  Rab7 regulates the dendritic trafficking of neuron-specific gene proteins (Nsg1 and Nsg2) to somatic lysosomes. C. Yap1, L. Digilio1, L. McMahon1, B. Winckler1; 1Cell Biology, University of Virginia Medical School, Charlottesville, VA B976/P1248  ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation. E. Koubek1, L.C. Santy1; 1Biochemistry, Microbiology, and Molecular Biology, The Pennsylvania State University, State College, PA B977/P1249  Ultrastructural dynamics of autophagy-related membrane myelination and subsequent exfoliation of gastric pitparietal cells in isolated rat gastric mucosa processed by high-pressure freezing. A. Sawaguchi1, F. Aoyama1, N. Takahashi1; 1Anatomy, University of Miyazaki, Faculty of Medicine, Miyazaki, Japan

B978/P1250  Overexpressed Flotillin-Induced Trafficking pathway promotes cell invasion and metastatic development. C. GauthierRouviere1, D. Planchon1, M. Genest1, E. Rios Morris1, F. Comunale1, P. Chavrier2, I. Bièche3, S. Linder4, S. Bodin1; 1CRBM, CNRS, Montpellier, France, 2Cell Dynamics and Compartimentalization, CURIE Institute, Paris, France, 3 Genetics, CURIE Institute, Paris, France, 4 Universitätsklinikum Eppendorf, Institut für Medecine, Hamburg, Germany B979/P1251  Identification of the retromer cargo landscape using quantitative proteomics. S. Swarup1, C. Bell1, J.A. Paulo1, S.P. Gygi1, J.W. Harper1; 1Department of Cell Biology, Harvard Medical School, Boston, MA B980/P1252  Distinct molecular mechanisms enable inward versus outward movement of membrane proteins from multivesicular endosomes. M.B. Gireud1,2, A.J. Bean1,2,3; 1Neurobiology and Anatomy, University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, 2Neurobiology and Anatomy, McGovern Medical School, Houston, TX, 3Department of Pediatrics, M.D. Anderson Cancer Center, Houston, TX B981/P1253  The Lowe Syndrome phosphoinositide phosphatase dOCRL restricts innate immune activation by regulating endosomal traffic. S.J. Del Signore1, S.A. Biber1, K.S. Lehmann1, T.L. Eskin1, A.A. Rodal1; 1 Rosenstiel Basic Medical Sciences Research Center, Department of Biology, Brandeis University, Waltham, MA B982/P1254  Rab4-effector Rabip4’ is a novel interaction partner of lysosomal small GTPase Arl8b. D. Khatter1, R. Marwaha1, M. Sharma1; 1Biological Sciences, Indian Institute of Science Education and Research Mohali, Mohali, India B983/P1255  Uropathogenic Escherichia coli invasion of human urinary epithelial cells utilizes the autophagy signaling pathway. A.E. Shea1, W. Kim1, D.C. Jimenez1, W.A. Dunn1, Y. Daaka1; 1Anatomy and Cell Biology, University of Florida, Gainesville, FL B984/P1256  Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex. E.L. Guiney1, T. Klecker1, S.D. Emr1; 1Molecular Biology and Genetics, Cornell University, Ithaca, NY B985/P1257  Mechanisms underlying membrane protein recycling from late endosomes. K. Memarzadeh1, M.B. Gireud1, A.J. Bean1; 1Department of Neurobiology and Anatomy, University of Texas Health Sciences Center at Houston, Houston, TX B986/P1258  Characterization of the ubiquitin ligase, UBE4B, in endocytic trafficking. N. Sirisaengtaksin1,2, A.J. Bean1,2,3; 1Neurobiology and Anatomy, UT Health McGovern Medical School, Houston, TX, 2University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, 3Division of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1000/P1259  Regulation of the exchange factor DENND3 through an intramolecular interaction. J. Xu1, P.S. McPherson1; 1Department of Neurology and Neurosurgery, McGill University, Montreal, QC B1001/P1260  A membrane trafficking screen to identify Clathrin-independent endocytosis machinery. J.L. Wayt1, D. Dutta1, J. Donaldson1; 1NHLBI, NIH, Bethesda, MD B1002/P1261  Characterization of the role of deubiquitylating enzyme USP3 in Clathrinindependent endocytosis (CIE) cargo specific trafficking. S. NIYOGI1, J.L. Wayt1, C. Williamson1, J. Donaldson1, L. Eshun-Wilson1; 1NHLBI, NIH, BETHESDA, MD

B1004/P1263  Cbl and Cbl-b control CSF-1R endocytic traffic and growth factor signaling in macrophages. L. Huang1,2, J. Lou1,2, N.W. Thiex1,2, J.G. Kerkvliet1,2, H. Band3, A.D. Hoppe1,2; 1BioSNTR, South Dakota State University, Brookings, SD, 2Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD, 3Department of Genetics, Cell Biology, Anatomy, University of Nebraska Medical Center, Omaha, NE B1005/P1264  Exploring the role of the schizophrenia-linked protein tSNARE1 in neuronal trafficking. M. Plooster1, G. Rossi2, M.S. Farrell3, P.F. Sullivan3,4, S.L. Gupton2,5,6, P. Brennwald2; 1Cell Biology and Physiology Curriculum, University of North Carolina, Chapel Hill, NC, 2Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 3Department of Genetics, University of North Carolina, Chapel Hill, NC, 4Department of Psychiatry, University of North Carolina, Chapel Hill, NC, 5Neuroscience Center, University of North Carolina, Chapel Hill, NC, 6Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC B1006/P1265  The Lowe Syndrome Protein OCRL1 is Required for Endocytosis in the Zebrafish Pronephric Tubule. F. Oltrabella1, G. Pietka2, I. Barinaga-Rementeria Ramirez3, A. Mironov3, T. Starborg3, I.A. Drummond4, M. Lowe3; 1Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, 2Molecular, The Royal Marsden NHS Foundation Trust, London, United Kingdom, 3Life Sciences, The University of Manchester, Manchester, United Kingdom, 4 Nephrology division, Massachusetts General Hospital, Charlestown, MA B1007/P1266  A huntingtin-mediated early stress response transiently halts endosomal trafficking. S. Nath1, L.N. Munsie2, R. Truant1; 1Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, 2Centre for Commercialization of Regenerative Medicine, Toronto, ON

Endosomes, Lysosomes, and Lysosome-Related Organelles 1 B1008/P1267  Expression and intracellular trafficking of the hyaluronidase HYAL1 in osteoclasts. E. Puissant1, M. . Jadot1, B. Flamion1, M. Boonen1; 1Molecular Physiology Research Unit, University of Namur, Namur, Belgium B1009/P1268  Cellular effects of distinct missense mutations at spastin residue 499 that result in clinically different neurologic syndromes. H. Boucekkine1,2,3, B. Renvoise3, L. Maldonado-Baez3, N.B. Cole3, C.D. Blackstone3; 1Medical Research Scholars Program, NIH, Bethesda, MD, 2University of Miami, Miller School of Medicine, Miami, FL, 3Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD B1010/P1269  Altered regulation of endocytic pathways in breast cancer. K.E. Tubbesing1, A. Malhotra1, A. Rudkouskaya1, M.M. Barroso1; 1Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY B1011/P1270  Evidence for a role of BLOC-1 in mouse brain development. F.Y. Lee1, A. Aiken2, O.N. Hitchcock2, C.Y. Kokikian2, R.S. Fisher2, E.C. DellAngelica1, C.A. Ghiani2,3; 1Human Genetics, University of California Los Angeles, Los Angeles, CA, 2Psychiatry and Biobehavioral Science, University of California Los Angeles, Los Angeles, CA, 3Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA B1012/P1271  TPD54 is associated with recycling vesicles and plays a role in cell migration. G. Larocque1, N.I. Clarke1, B. Wilson2, P. Caswell2, S.J. Royle1; 1Medical school, University of Warwick, Coventry, United Kingdom, 2Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom B1013/P1272  The Role of Ent Proteins in Nitrogen-Regulated Growth of Saccharomyces cerevisiae. O. Haile1, R. Ramirez1, A. MacFarlane1, Q.L. Aoh1; 1Biology, Gannon University, Erie, PA B1014/P1273  TPC2 controls pigmentation by regulating melanosome pH and size. A.L. Ambrosio1, J.A. Boyle1, A.E. Aradi1, K.A. Christian1, S.M. Di Pietro1; 1Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B1015/P1274  Mechanisms of melanin transfer from melanocytes and formation of a parasol in keratinocytes. M.C. Seabra1,2, D.C. Barral1, M.S. Correia1, F.J. Pereira1, A.K. Tarafder3; 1CEDOC, Chronic Diseases Research Center, NOVA Medical School, Lisbon, Portugal, 2Molecular Medicine, NHLI, Imperial College London, London, United Kingdom, 3 EMBL, Heidelberg, Germany B1016/P1275  Altered lysosome positioning perturbs critical homeostatic functions in the retinal pigment epithelium. L. Tan1,2, K.A. Toops2, A. Lakkaraju1,2; 1Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI, 2Ophthalmology and Visual Sciences, McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1017/P1276  VMAT2 segregates from endolysosomes to dense granules during megakaryocyte maturation to proplatelets. H.A. Hanby1,2,3,4, S.M. Di Pietro5, M.S. Marks2,3,4; 1Cell and Molecular Biology Graduate Group, University of Pennsylvania, Philadelphia, PA, 2Pathology and Laboratory Medicine, CHOP, Philadelphia, PA, 3Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 4Physiology, University of Pennsylvania, Philadelphia, PA, 5 Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B1018/P1277  CXCL12-induced macropinocytosis modulates two distinct pathways to trigger mTORC1 activation in macrophages. S. Yoshida1, R. Pacitto1, J.A. Swanson1; 1Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI B1019/P1278  Deleting the Saccharomyces cerevisiae diacylglycerol kinase Dgk1 augments vacuole fusion by increasing diacylglycerol levels as well as enhancing V-ATPase activity. G. Miner1, M.L. Starr1, L. Hurst1, T. Sasser1, A. Chang1, R. Fratti1; 1Biochemistry, University of Illinois at UrbanaChampaign, Urbana-Champaign, IL B1020/P1279  Sortilin and retromer maintain normal levels of the Glut4 protein in adipocytes by retrieving it from degradation into the recycling pathway. X. Pan1, M. Singh1, K. Kandror1; 1Biochemistry, Boston University School of Medicine, Boston, MA B1021/P1280  The Cytosolic Sensor ELMO1 Regulates Endosomal-Lysosomal Signaling During Bacterial Clearance. R. Pranadinata1, C. Tindle1, A. Quaile2, A. Savchenko2, P. Ernst1, S. Das1; 1Pathology, University Of California San Diego, La Jolla, CA, 2Chemical Engineering and Applied Chemistry, University of Toronto Faculty of Applied Science and Engineering, Toronto, Canada B1022/P1281  Assessment of VPS18 as candidate gene in an individual with undiagnosed disease and abnormal glycosylation. M.E. Hackbarth1,2, M.S. Kane1,2,3, M. Davids1,2, M. He4,5, L. Wolfe1,2, D.R. Adams1,2, W.A. Gahl1,2, M.V. Malicdan1,2; 1Office of the Clinical Director, NHGRI, National Institutes of Health, Bethesda, MD, 2NIH Undiagnosed Diseases Program, NHGRI, National Institutes of Health, Bethesda, MD, 3Inova Fairfax Hospital, Falls Church, VA, 4 The Michael J Palmiere Metabolic Laboratory, Children’s Hospital of Philadelphia, Philadelphia, PA, 5Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA B1023/P1282  JIP3-dependent regulation of axonal lysosome abundance protects against amyloid plaque pathology. S. Gowrishankar1, Y. Wu1, S.M. Ferguson1; 1Cell Biology, Yale University, School of Medicine, New Haven, CT B1024/P1283  Endoplasmic reticulum localization of the Rheb GTPase: Implications for mTORC1 activation. B.L. Angarola1, S.M. Ferguson1; 1Cell Biology, Yale University, New Haven, CT

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B1003/P1262  New Apical-to-basolateral Transcytotic Pathway: Inducible AND Actin- but not Microtubule-dependent. C.P. Grabowski1,2, E. de la Fuente3, L. Sandoval1, F.A. Sánchez4, A. González1,2; 1Center for Aging and Regeneration. Facultad de Ciencias Biológicas, Universidad Católica de Chile, Santiago, Chile, 2Facultad de Ciencia and Facultad de Medicina, Universidad San Sebastián, Santiago, Chile, 3Ciencias Biomédicas, Universidad Católica del Norte, Coquimbo, Chile, 4Instituto de Inmunologia, Facultad de Medicina. Universidad Austral de Chile, Valdivia, Chile

Monday Poster Session

Board No./Presentation No.

Post-Golgi Trafficking B1025/P1284  Arf-1-mediated protein trafficking to hydrogenosomes in Trichomonas vaginalis. J. Tai1; 1Infectious Diseases and Immunology, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan B1026/P1285  Differential sorting of planar cell polarity signaling receptors, Frizzled6 and Vangl2, at the trans Golgi Network. Y. Guo1, T. Ma1, R. Wang1, P. Lau1, Y. Huang1, R.W. Schekman2; 1Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, Hong Kong, 2Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA B1027/P1286  A biophysical approach to monitor Arf1 mediated AP-1 activation in vivo. E. Sauvageau1, S. Lefrancois1, P. McCormick2; 1Centre INRS-Institut Armand-Frappier, Laval, QC, 2School of Pharmacy, University of East Anglia, Norwich, United Kingdom B1028/P1287  The Golgi-associated RAB6 GTPase: a general regulator of post-Golgi trafficking? A. Kasri1, C.S. Gomes-Santos†1, S. Bardin1, N. Gareil2, L. Fourriere 2, G. Boncompain2, B. Goud1, F. Perez2, S. Miserey-Lenkei1; 1 CNRS/UMR144, Molecular Mechanisms of Intracellular Transport laboratory, Institut Curie, Paris, France, 2 CNRS/UMR144, Dynamics of Intracellular Organization laboratory, Institut Curie, Paris, France B1029/P1288  Routing of the RAB6 secretory pathway towards a lysosome-related organelle. A. Patwardhan1, S. Bardin1, S. MisereyLenkei1, L. Larue2, B. Goud1, G. Raposo1, C. Delevoye1; 1Cell Biology Department, CNRS UMR144, Institut Curie, Paris, France, 2INSERM U1021, CNRS UMR3347, Institut Curie, Université Paris Sud, Paris, France B1030/P1289  Golgi-dependent mechanisms control mitochondrial copper homeostasis. H.S. Comstra1, A. Gokhale1, S. Zlatic1, D.B. Barr2, J.B. Blackburn3, V.V. Lupashin3, V. Faundez1; 1Cell Biology, Emory University, Atlanta, GA, 2Rollins School of Public Health, Emory University, Atlanta, GA, 3Physiology Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR B1031/P1290  Identifying Protein Cargo Recognized by Atg27. D.C. Lee1, V.A. Segarra1; 1Biology, High Point University, High Point, NC B1032/P1291  Yeast dynamin association with clathrin and its physiological roles. S. Gadila1, U. Saimani1, M.A. Williams2, M. Delgado Cruz1, P. Makaraci1, K. Kim1; 1Biology, Missouri State University, Springfield, MO, 2Division of Biological Sciences, University of Missouri, Columbia, MO B1033/P1292  Golgi Fragmentation in Alzheimer’s Disease. M.E. Bekier1, D. Rector1, X. Wang1, Y. Wang1; 1Molecular, Cellular, Developmental Biology, University of Michigan, Ann Arbor, MI B1034/P1293  A Role for Diacylglycerol Kinase γ in Membrane Trafficking at the Golgi and TGN. K.D. Thorsen1, K.D. Ha1, L. Velez-Velez1, W.J. Brown1; 1Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY

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Monday Poster Session B1035/P1294  AP-3 and PICK1-ICA69 Function at Distinct Steps in Dense Core Vesicle Biogenesis. B.A. Heller1, S. Jain1, B. Hummer2, T. Logan1, C.S. Asensio2, R.H. Edwards1,3; 1Department of Neurology, University of California, San Francisco, San Francisco, CA, 2Department of Biological Sciences, University of Denver, Denver, CO, 3Department of Physiology, University of California, San Francisco, San Francisco, CA B1036/P1295  Iterative sorting of apical and basolateral cargo in MDCK cells. A. Treyer1, M. Pujato1, X. Pechuan1, A. Muesch1; 1Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY B1037/P1296  Analysis of Protein Sorting at The Trans Golgi Network Through STORM Super-Resolution Imaging. P. Lau1, Y. Huang1, T. Zhao2, D. Xu3, S. Du2, M. Loy2, Y. Guo1; 1Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong, 2Department of Physics, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong, 3Nanobioimaging Limited, Hong Kong, Hong Kong B1038/P1297  Hyperglycemia Regulates Trafficking and Turnover of Human Islet Amyloid Polypeptide in the Pancreatic Islets. D. Chatterjee Bhowmick1,2, A.M. Jeremic2; 1Biomedical Sciences, The George Washington University, Washington, DC, 2Biological Sciences, The George Washington University, Washington, DC B1039/P1298  Regulated Late Golgi Sorting Underlies Aging and Rejuvenation. K.A. Henderson1, J.V. Rogers2, P.B. Gordon1, D.E. Gottschling1,2; 1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 2Calico Life Sciences, LLC, South San Francisco, CA

Neuronal Protein and Organelle Trafficking B1041/P1299  A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation. A.L. Neisch1, T.P. Neufeld1, T.S. Hays1; 1Genetics, Cell biology and Development, University of Minnesota, Minneapolis, MN B1042/P1300  Dynamic regulation of autophagy in neurons during aging. A.K. Stavoe1, E.L. Holzbaur1; 1Physiology, University of Pennsylvania, Philadelphia, PA B1043/P1301  Neep21 is a novel effector of the TrkA signaling endosome. K. Barford1,2, C. Yap1, C. Deppmann3, B. Winckler1; 1Dept. of Cell Biology, University of Virginia, Charlottesville, VA, 2Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, 3Dept. of Biology, University of Virginia, Charlottesville, VA B1044/P1302  An ankyrin-B/beta-2 spectrinbased mechanism regulates axonal organelle transport and axonal growth. D.N. Lorenzo1,2, A. Badea3,4, G. Johnson3,4, V. Bennett1; 1Biochemistry, Duke University, HHMI, Durham, NC, 2Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Radiology, Duke University, Durham, NC, 4Center for in vivo microscopy, Duke University, Durham, NC

B1045/P1303  Spatial control of axon-dendritic membrane traffic by microtubule-associated septins. E.P. Karasmanis1, E.T. Spiliotis1; 1Biology, Drexel University, Philadelphia, PA B1046/P1304  Different cargo receptors, APP and Alcα, transport the same cargos cooperatively through the identical vesicular transport pathway. Y. Shiraki1, K. Chiba1, S. Hata1, T. Suzuki1; 1Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan B1047/P1305  The regulation of mitochondrial trafficking in activity-dependent structural synaptic plasticity. R. Insolera1, R. Wang1, E. Robertson1, Y. Xie1,2, L.M. Rivera-Perez1,3, X. Xiong1, Y. Fridell4, C.A. Collins1; 1Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 2Summer Research Opportunity Program, University of Michigan, Ann Arbor, MI, 3Post-baccalaureate Research Education Program (PREP), University of Michigan, Ann Arbor, MI, 4Allied Health Sciences, University of Connecticut, Storrs, CT B1048/P1306  Transport Dynamics of JIP-1 Nano-Beads and Statistical Modelling of Cargo-Motor Interactions in Squid Giant Axon. S. Bojja1,2, P. Dogra1, E.L. Bearer1; 1Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM, 2Computer Science, University of New Mexico, Albuquerque, NM B1049/P1307  ALS-linked mutations increase the viscosity of liquid-like axonal TDP-43 RNP granules in neurons. P.P. Gopal1,2, J.J. Nirschl1, E. Klinman1, E.L. Holzbaur1; 1Perelman School of Medicine, Physiology Department, University of Pennsylvania, Philadelphia, PA, 2Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA B1050/P1308  Presynaptic morphology and vesicular composition influence vesicle dynamics in central synapses. L. Guillaud1, D. Dimitrov1, T. Takahashi1; 1Cellular and Molecular Synaptic Function Unit, Okinawa Institute of Science and Technology, Onna-son, Japan B1051/P1309  A new function of the Golgi ARF1-exchange factor (GBF1) over TRPM8 ion channel activity in isolated peripheral nerve endings. V.H. Cornejo1,2, M. Campos3, R. Madrid3, A. Couve1,2; 1Program of Physiology and Biophysics, Universidad de Chile, Santiago, Chile, 2Biomedical Neuroscience Institute, Universidad de Chile, Santiago, Chile, 3 Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago, Santiago, Chile B1052/P1310  Kainate receptor biogenesis and secretory pathway trafficking forward to the cell surface is under strict control by neuronal cellular activity. A.J. Evans1, S. Gurung1, K.A. Wilkinson1, D.J. Stephens1, J.M. Henley1; 1Biochemistry, The University of Bristol, Bristol, United Kingdom B1053/P1311  -actinin Promotes Surface Localization and Ion Channel Activity of the Ca2+ Channel CaV1.2 by Binding to the IQ Region of the 1 Subunit. P. Tseng1, P.B. Henderson1, M. Lillya1, C. Montagut1, B. Lee1, J.W. Hell1, M.C. Horne1; 1Pharmacology, University of California Davis, Davis, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1054/P1312  Role of Huntingtin in synaptic capture of circulating neuropeptide vesicles in Drosophila motor nerve terminals. D. Bulgari1, E.S. Levitan1; 1Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA B1055/P1313  Recruitment of Dynein by Calcyon Stimulates Retrograde Movement of Lysosome Related Organelles In Axons. L. Shi1, N. Muthusamy2, D. Smith1, C. Bergson3; 1Biological Sciences, University of South Carolina, Columbia, SC, 2Neuroscience Center, University of North Carolina, Raleigh, NC, 3Pharmacology and Toxicology, Augusta University, Augusta, GA

Neuronal Degeneration and Regeneration B1056/P1314  Macrophages act on axotomized neuronal cell bodies to stimulate peripheral axonal regeneration via a JAK/ STAT pathway. R.E. Zigmond1, J.P. Niemi1, A. DeFrancesco1; 1Neurosciences, Case Western Reserve University, Cleveland, OH

B1058/P1316  The impact of extended synaptotagmin mistrafficking on nervous system function and life span. C. Liang1, A. Ghosh1, J. Dittman1, Y. Dong2, J. Bai2; 1Biochemistry, Weill Cornell Medical College, New York, NY, 2 Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA B1059/P1317  ADAMTS9 regulates cell-cell interactions and myelination in the central nervous system. S.D. Ackerman1,2, A. Soung1, B. Harty1, R.G. Almeida3, S. Nandadasa4, A.L. Herbert1, C. Johnson1, C. Raciti1, S.S. Apte4, D.A. Lyons3, K.R. Monk1; 1Developmental Biology, Washington University School of Medicine, Saint Louis, MO, 2Institute of Neuroscience, University of Oregon, Eugene, OR, 3University of Edinburgh, Centre for Neuroregeneration, Edinburgh, United Kingdom, 4Cleveland Clinic Lerner Research Institute, Department of Biomedical Engineering, Cleveland, OH B1060/P1318  Glia to Muscle Trans-Synaptic Signaling is Necessary for Neuromuscular Degeneration. C. Blais1, E. Dalaker1, E. Danella1, N. Girard1, P. Peterson2, L.C. Keller1; 1Biological Sciences, Quinnipiac University, Hamden, CT, 2Medical School, Quinnipiac University, Hamden, CT B1061/P1319  Monitoring Dendrite Regeneration after Injury in vivo. K.L. ThompsonPeer1,2, L. DeVault1,2, T. Li1,2, L.Y. Jan1,2, Y.N. Jan1,2; 1Physiology, University of California, San Francisco, CA, 2Howard Hughes Medical Institute, San Francisco, CA

B1062/P1320  Mechanisms underlying gainof-function toxicity of pathogenic SPAST mutations associated with hereditary spastic paraplegia. L. Leo1, G. Morfini2, G.M. Alexander3, J.M. Solowska1, W. Yu1, L.E. Hennessy3, L. Qiang1, P. Yates1, M. Burns2, C. Weissmann2, T.D. Heiman-Patterson3, P.W. Baas1; 1Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 2Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, 3Neurology, Drexel University College of Medicine, Philadelphia, PA B1063/P1321  The Role of Muscle-Restricted Expression of NRIP in Motor Neuron Survival. H. Chen1, S. Chen1; 1Microbiology, National Taiwan University, Taipei, Taiwan B1064/P1322  Efffcts of retino-collicular coculture system on the neuroprotection of retinal ganglion cells. J. Ko1, C. Hiraoka1, H. Okumichi1, Y. Kimchi1; 1Ophthalmology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan B1065/P1323  Does S129 phosphorylation of alpha-synuclein contribute to neuronal cell death or axonal pathology? N. Ramalingam1, C.A. Walker2, E. Kanter1, U. Hengst2, D. Sulzer3, D.J. Selkoe4, U. Dettmer4, O.A. Levy1; 1Neurology, Columbia University, New York, NY, 2Pathology Cell Biology, Columbia University, New York, NY, 3Psychiatry, Neurology, Pharmacology, Columbia University, New York, NY, 4Ann Romney Center for Neurologic Diseases, Harvard Medical School, Boston, MA B1066/P1324  Neuronal Responses to LaserInduced Shockwave: A Method to Study Nerve Damage and Repair. V. Morar1, V. Gomez1, D. Preece1, L. Shi1, C. Wu1, M. Berns1; 1Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA

Mitochondria, Chloroplasts, and Peroxisomes 2 B1067/P1325  A genome wide screen identifies Myotonic Dystrophy Protein Kinase (DMPK) as a novel ER-mitochondria tether. S. Lakshminarayanan1, A. Serafini1, M. Giacomello1,2, L. Scorrano1,3; 1Department of Biology, University of Padova, Padova, Italy, 2 Fondazione Ospedale San Camillo, IRCCS, Lido di Venezia, Venezia, Italy, Venezia, Italy, 3 Venetian institute of molecular medicine, Padova, Italy B1068/P1326  The Effect of Altered Fission Rates or Fusion Rates on Mitochondria Network Morphology through Controlled Expression of DNM1 and FZO1 in Budding Yeast. K. Sumikawa1, I.A. Mueller1, M. Bialecka-Fornal1, T. Tsuboi1, S.S. Lim1, V. Jayashankar1, S.M. Rafelski1; 1Developmental and Cell Biology, University of California, Irvine, Irvine, CA B1069/P1327  T-cell-restricted intracellular antigen 1 facilitates mitochondrial fragmentation by enhancing the expression of mitochondrial fission factor. E. Lee1, W. Kim2; 1Department of Biochemistry, The Catholic University of Korea College of Medicine, Seoul, Korea, South, 2Department of Molecular Science and Technology, Ajou University, Suwon, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1070/P1328  Suppressing mitochondrial division rescues nucleoid distribution in Mitofusin knockout MEF cells. L.F. Uchiyama1, S.C. Lewis1, J. Nunnari1; 1Dept. of Molecular and Cellular Biology, University of California, Davis, CA B1071/P1329  An inducible ER-Golgi tether facilitates ceramide transport to alleviate lipotoxicity. L. Liu1; 1NIDDH, NIH, BETHESDA, MD B1072/P1330  Keratins regulate β-cell mitochondrial morphology, motility and homeostasis. J.S. Silvander1, S.M. Kvarnström1, A. Kumari-Ilieva1, C.M. Alam1, D.M. Toivola1; 1Cell Biology, Åbo Akademi University, Turku, Finland B1073/P1331  Endosome-mitochondria interactions are modulated by iron release from transferrin. A. Das1, M.M. Barroso1; 1Molecular & Cellular Physiology, Albany Medical College, Albany, NY B1074/P1332  Adaptors MiD49/51 and Mff preferentially partition into CL-enriched microdomains to cooperatively regulate Dynamin-related protein 1 (Drp1)-mediated mitochondrial fission. R. Ramachandran1, N. Stepanyants1, P. MacDonald1; 1Physiology & Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH B1075/P1333  Mitochondrial Quality Control for Misfolded De Novo MT-ATP6 of the ATP Synthase. T. Lahtinen1, K. Ng1, F. Suomi1, P. Marttinen1, U. Richter1, B.J. Battersby1; 1Institute of Biotechnology, University of Helsinki, Helsinki, Finland B1076/P1334  A novel regulator of mitochondrial DNA copy number identified by an unbiased genetic screen. A. Göke1,2, C. Osman1,2, R.E. Diaz1,2,3, P. Walter1,2; 1Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA, 2Howard Hughes Medical Institute, San Francisco, CA, 3Undergraduate Neuroscience Program, University of Miami, Miami, FL B1077/P1335  Structure-function analysis of mitochondrial networks reveal heterogeneity of ultrastructural features as well as the interplay between inheritance and quality control. S. Lim1, M. Viana2, S.M. Rafelski1; 1Dev and Cell Biology, University of California, Irvine, Irvine, CA, 2IBM Research Brazil, Sao Paolo, Brazil B1078/P1336  Novel mutations in the substrate binding domain of the mitochondrial matrix protease LonP1 are a cause of mitochondrial disease. M.T. Simon1,2, S. Eftekharian2, A. Stover2, M.A. Steeves3, I. Sahai3, S. Tang4, R. Wang2,5, J. Abdenur2,5, S.M. Rafelski1; 1Developmental and Cellular Biology, University of California Irvine, Irvine, CA, 2Metabolics, CHOC Childrens, Orange, CA, 3Genetics, Massachusetts General Hospital, Boston, MA, 4Ambry Genetics, Aliso Viejo, CA, 5Pediatrics, University of California Irvine, Irvine, CA B1079/P1337  Yeast as a model for the study of RNA-binding proteins and their role in cell physiology. D. Zabezhinsky1, J. Gerst1; 1Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

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B1057/P1315  Identification of genes that promote axonal regeneration of injured cortical neurons. C. Chang1, L. Chen1; 1Institute of Molecular Medicine, National Tsing Hua University, Taiwan, Hsinchu, Taiwan

Monday Poster Session

Board No./Presentation No. B1080/P1338  Rewiring mitochondrial phosphatidylethanolamine metabolism in Saccharomyces cerevisiae. E. Calzada1, S.M. Claypool1; 1Physiology, Johns Hopkins University School of Medicine, Baltimore, MD B1081/P1339  Functional expression of mammalian mitochondrial phosphate carrier in yeast cells. R. Yamagoshi1,2, T. Yamamoto1,2, M. Hashimoto3, H. Terada4, Y. Shinohara1,2; 1Institute for Genome Research, Tokushima University, Tokushima, Japan, 2Faculty of Pharmaceutical Sciences, Tokushima University, Tokushima, Japan, 3Faculty of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Japan, 4Niigata University of Pharmacy and Applied Life Sciences, Niigara, Japan B1082/P1340  Vespa amino acid mixture (VAAM) exposure in cultured yeast cells leads to increased production of reactive oxygen species (ROS) in short periods of time causing increased cellular degradation. A.I. Mohamed1, S.R. Stowers1, K. Clark1, M. Dameron1, S.B. Redmond1; 1Biology, Radford University, Radford, VA B1083/P1341  Negative impacts of vespa amino acid mixture (VAMM) on NAD+/NADH balance in yeast are neutralized by both antioxidants and 2,4-dinitrophenol. S.R. Stowers1, A. Mohamed 1, K. Clark1, M. Dameron1, S.B. Redmond1; 1Biology, Radford University, Radford, VA B1084/P1342  Analysis of the outer membrane insertion mechanism of yeast mitochondrial proteins. J. Song1, Y. Tamura2, T. Yoshihisa3, T. Endo4; 1Science, Nagoya University, Nagoya, Japan, 2Science, Yamagata University, Yamagata, Japan, 3Science, University of Hyogo, Hyogo, Japan, 4Biological Sciences , Kyoto Sangyo University, Kyoto, Japan B1085/P1343  An ER-bound sub-population of the tail-anchored protein Mff plays a role in mitochondrial division. w. ji1, H.N. Higgs1; 1Biochemistry and Cell Biology, Dartmouth College, Hanover, NH B1086/P1344  Nuclear-mitochondrial proximity accompanies organelle segregation in yeast gametogenesis. E.M. Sawyer1, K.L. McDonald2, E. Ünal1; 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Electron Microscope Laboratory, University of California, Berkeley, Berkeley, CA B1087/P1345  The biogenesis of a mitochondria-plasma membrane anchor. L.M. Kraft1, H.A. Ping1, W. Chen1, L.L. Lackner1; 1Molecular Biosciences, Northwestern University, Evanston, IL B1088/P1346  De-orphaning human metabolic enzymes of unknown function. H. Shen1, V.K. Mootha1; 1Department of Molecular Biology, Massachusetts General Hospital, Boston, MA B1089/P1347  CDK5 regulates mitochondrial permeability transition pore opening. S. NavaneethaKrishnan1, J. L. Rosales2, K. Lee1; 1Cell Biology and Anatomy, University of Calgary, Calgary, AB, 2Biochemistry and Molecular Biology, University of Calgary, Calgary, AB

Monday Poster Session

Lipids and Membrane Microdomains 2 B1100/P1348  Septin 9 binds phosphatidylinositol-5-phosphate to assemble and control lipid droplet accumulation. A. Gassama1; 1Hepatobiliairy center, INSERM, Unité 1193, Villejuif F-94800, France, Villejuif, France B1101/P1349  Developmentally regulated histone/lipid droplet interactions control nuclear histone levels in Drosophila embryos. M.R. Johnson1, M.A. Welte1; 1Biology, University of Rochester, Rochester, NY B1102/P1350  Syntaxin 17 promotes lipid droplet formation by regulating the distribution of ACSL3, a key enzyme for lipid droplet biogenesis. H. Kimura1, K. Arasaki1, M. Tagaya1; 1school of life sciences, Tokyo university of pharmacy and life sciences, Tokyo, Japan B1103/P1351  Elimi-NAD-ing fat from old mother yeast cells. A.O. Beas1, J.C. Berude1, J. Hsu1, D.E. Gottschling1; 1Basic Sciences, Fred Hutch Cancer Research Center, Seattle, WA B1104/P1352  The larval zebrafish as a model for investigating how lipid droplet-associated perilipin proteins regulate dietary lipid absorption in the intestine. M.H. Wilson1, E.M. Zeituni1, V.H. Quinlivan-Repasi1,2, S.A. Farber1,2; 1Department of Embryology, Carnegie Institution for Science, Baltimore, MD, 2Department of Biology, Johns Hopkins University, Baltimore, MD B1105/P1353  Inward tubulation of the plasma membrane expedites membrane exchange and receptor presentation. L. Cai1, L. Zhou1, L. Yao1; 1Biochemistry, Fudan University, Shanghai, China B1106/P1354  Plasma Membrane of NonSenescent Keratinocytes Contain Sphingomyelin-rich Submicrometric Lipid Domains Involved in Re-epithelialization. A. Mound1, C. Warnon2, J. Robic3, C. Guere3, K. Vie3, C. Lambert de Rouvroit1, D. Tyteca4, F. DebacqChainiaux2, Y. Poumay1; 1URPHYM-NARILIS, University of Namur, Namur, Belgium, 2URBCNARILIS, University of Namur, Namur, Belgium, 3Laboratoires Clarins, Pontoise, France, 4 CELL-de Duve Institute, Université Catholique de Louvain, Brussels, Belgium B1107/P1355  Membrane raft association serves as a sorting platform for intracellular protein trafficking. B.B. Diaz-Rohrer1, J.H. Lorent2, K.R. Levental2, I. Levental2; 1The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, 2Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, TX B1108/P1356  Exploring the membrane-actin linkage that facilitates acto-myosin mediated GPI-AP nanoclustering. A.A. Anilkumar1, J. Kalappurakkal1, S. Mayor1,2; 1Cellular organization and signalling, National Centre for Biological Sciences, Bangalore, India, 2Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India B1109/P1357  Glycolipid crosslinking is re-

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quired for cholera toxin to partition into and stabilize ordered domains. K. Raghunathan1, T.H. Wong1, D.J. Chinnapen2, W.I. Lencer2, M.G. Jobling3, A.K. Kenworthy1,4; 1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 2 Harvard Digestive Diseases Center, Harvard Medical School, Boston, MA, 3Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, 4Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN B1110/P1358  α-SNAP Regulates Dynamic, On-Site Assembly and Calcium Selectivity of Orai1 Channels. P. Li1, Y. Miao1, A. Dani1, M. Vig1; 1Washington University in St Louis, School of Medicine, St Louis, MO B1111/P1359  Image Correlation Spectroscopy and Single Particle Tracking Reveal Plasma Membrane Nanoscaled Clustering of the Angiotensin Receptor. T.E. Rasmussen1, P.W. Wiseman2, E.C. Arnspang3; 1MEMPHYS - Center for Biomembrane Physics, University of Southern Denmark, Odense, Denmark, 2 Department of Physics, McGill University, Montreal, Canada, 3Department of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, Odense, Denmark B1112/P1360  Phospholipid flippase ATP10A, a member of type IV P-type ATPases, translocates phosphatidylcholine and is involved in plasma membrane dynamics. T. Naito1, H. Takatsu1, R. Miyano1, N. Takada1, K. Nakayama1, H. Shin1; 1Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan B1113/P1361  Cellular reprogramming into Brown Adipose Tissue (BAT) –like cells is independent of mature Heparin-binding EGF-like growth Factor (HB-EGF) and HBEGF C domains. S.R. Taylor1, D.C. Pfeil2,3, C.A. Gemma2, E.R. Miller2,4, P.A. Harding1,2; 1Department of Biology - Cell, Molecular, and Structural Biology Program, Miami University, Oxford, OH, 2Department of Biology, Miami University, Oxford, OH, 3Department of Mechanical and Manufacturing Engineering, Miami University, Oxford, OH, 4Department of Microbiology, Miami University, Oxford, OH B1114/P1362  Functional Analysis of the PI4P/ PS Transfer Properties of ORP5 AND ORP8. M. Sohn1, T. Balla1; 1National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, MD B1115/P1363  Organization of the Leukotriene Synthetic Complex in Neutrophils as an Indicator of Disease State. A.B. Schmider1, M. Godin1, H.D. Elliott2, R.J. Soberman1; 1Nephrology, Massachusetts General Hospital, Charlestown, MA, 2Cell Biology, Harvard Medical School, Boston, MA B1116/P1364  Dynamics and nanoscale organization of key players in the de novo sphingolipid synthesis pathway unveiled by genetically encoded fluorescent reporters and super-resolution microscopy. P. Chandris1,2, S. Gupta3, C. Giannouli2, T. Dunn3, H. Shroff1, R. Proia2; 1Section on high resolution optical imaging, NIH, NIBIB, Bethesda, MD, 2 Genetics of Development and Disease Branch, NIH, NIDDK, Bethesda, MD, 3Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, MD

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Post-Translational Modifications in Signaling B1118/P1365  Determining roles for reversible lysine acetylation in the regulation of actin cytoskeletal dynamics. J. Aslan1, R. Rigg2, A. Ngo2, J. Nelson1, J. Burchard3, L. David4, O. McCarty2; 1Knight Cardiovascular Institute, Oregon Health Science University, Portland, OR, 2Biomedical Engineering, Oregon Health Science University, Portland, OR, 3Computational Biology, Oregon Health Science University, Portland, OR, 4Proteomics Shared Resource, Oregon Health Science University, Portland, OR B1119/P1366  Activation of synaptic NR2ANMDAR/CaMKII complexes reactivates structural plasticity in mature hippocampal neurons through p300/CBP-mediated acetylation of histone H3 lysine 27. B. Van Zundert1, F.J. Bustos1,2, N. Jury1, E. Ampuero1, M. Sanchez1,2, S. Abarzua1,2, P. Martinez1, L. Varela1, M. Montecino1,2; 1Center for Biomedical Research, Universidad Andres Bello, Santiago, Chile, 2FONDAP Center for Genome Regulation, Santiago, Chile

B1121/P1368  Changes in O-GlcNAcylation regulate stabilization and activation of p53 in ovarian carcer. R.M. De Queiroz1, R. Madan2, J. Chien2, W.B. Dias1, C. Slawson3; 1Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, 2Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, 3Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS B1122/P1369  Balancing Cell Growth and Apoptosis by Protein O-GlcNAcylation. L.K. Abramowitz1, J.A. Hanover1; 1NIDDK, National Institutes of Health, Bethesda, MD B1123/P1370  The role of human UDP-galactose 4’-epimerase in ER stress signaling. A. Broussard1, N. Nischan2, J.J. Kohler2, M. Boyce1; 1Department of Biochemistry, Duke University, Durham, NC, 2Deptartment of Biochemistry, University of Texas Southwestern, Dallas, TX B1124/P1371  Spatial regulation of myosin V transport via the PAK kinase, Cla4. S. Wong1, R.G. Yau1, L.S. Weisman1; 1Cell and Developmental Biology, Cell and Molecular Biology Training Program, Life Sciences Institute, University of Michigan, Ann Arbor, MI B1125/P1372  Divergent effects of Porcupine and Wntless on WNT1 trafficking, secretion, and signaling. L.M. Galli1, N. Zebarjadi1, L. Li1, V.R. Lingappa2, L.W. Burrus1; 1Biology, San Francisco State University, San Francisco, CA, 2 Prosetta Biosciences, Inc., San Francisco, CA B1126/P1373  Inhibition of Atypical Protein Kinase C and Histone Deacetylase 1 synergistically arrests GLI nuclear maturation in basal cell carcinoma. A. Mirza1, A.E. Oro1; 1Dermatology, Stanford School of Medicine, Stanford, CA

B1127/P1374  Mitochondrial ROS regulation and osteoclast differentiation. H. Kim1, Y. Lee1, H. Kim1; 1Cell and Developmental Biology, Seoul National University, Seoul, Korea, South B1128/P1375  Systemic insulin sensitivity is regulated by GPS2 through inhibition of AKT ubiquitination and activation in adipose tissue. C.T. Cederquist1, M. Lee1, C. Martinez-Calejman2, V. Hayashi1, J. Orofino1, C. Lentucci1, D. Guertin2, S. Fried3, M.D. Cardamone1, V. Perissi1; 1Biochemistry, Boston University School of Medicine, Boston, MA, 2 University of Massachusetts Medical School, Worcester, MA, 3Mount Sinai School of Medicine, New York, NY B1129/P1376  Insulin action on protein synthesis and its association to eIF5A expression and hypusination. A.R. Proenca1, K.D. Pereira1,2, L. Meneguello1,2, L. Tamborlim1, A.D. Luchessi1,2; 1Biotechnology Lab., University of Campinas, Limeira - Sao Paulo, Brazil, 2Institute of Biosciences, Sao Paulo State University, Rio Claro - Sao Paulo, Brazil B1130/P1377  Oxidized LDL and Disturbed Flow Increase eNOS and Caveolin-1 Phosphorylation. C. Coles1, E. Lemaster2, Z. Chen3, S. D’Arc Oliveira3, I. Levitan2,4, R.D. Minshall1,3; 1Pharmacology, University of Illinois at Chicago, Chicago, IL, 2Bioengineering, University of Illinois at Chicago, Chicago, IL, 3Anesthesiology, University of Illinois at Chicago, Chicago, IL, 4Medicine, University of Illinois at Chicago, Chicago, IL B1131/P1378  Role of cereblon in molecular and cellular mechanism of AMPK inhibition. K. LEE1, C. Park2; 1Korea Food Research Institute, Gyeonggi-do, Korea, South, 2Gwangju Institute Science and Technology, Gwangju, Korea, South B1132/P1379  Mass-Spectrometric Identification and Characterization of an Ana o 3 Modification Site. C.P. Mattison1, C.C. Grimm1, Y. Li1, H.J. Chial2, D.R. McCaslin3, S. Chung1, Y. Bren-Mattison2, R.L. Wasserman4; 1USDA-ARS, New Orleans, LA, 2BioMed Bridge, LLC, Denver, CO, 3Biochemistry Dept, University of Wisconsin, Madison, WI, 4Department of Pediatrics, Allergy Partners of North Texas Research, Dallas, TX B1133/P1380  Sumoylation, An Important Post-Translational Modification Controls both Cell Division and Differentiation in the Ocular Lens. D.W. Li1,2,3, Y. Liu1, L. Gong1, L. Zhang1; 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yatsen University, Guangzhou, China, 2Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, NE, 3Key Laboratory of Protein Chemistry Developmentl Biology, College of Life Sciences, Hunan Normal University, Changsha, China B1134/P1381  Autophagy negatively regulates Notch1 signaling by promoting Notch1-IC degradation through Fbw7 E3 ligase. J. Ahn1, H. Lee1, H. Park1; 1Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1135/P1382  Fe65 accelerates the degradation of Jagged1 via recruitment of the E3 ligase Neuralized-like 1. H. Lee1, J. Ahn1, H. Park1; 1Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Korea, South B1136/P1383  Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer’s disease. H.T. Vu1, H. Akatsu2,3, Y. Hashizume2, M. Setou1, K. Ikegami1; 1Department of Cellular Molecular Anatomy and International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Japan, 2Choju Medical Institute, Fukushimura Hospital, Toyohashi, Japan, 3Department for Medicine for Aging in Place and Community-Based Medical Education, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan B1137/P1384  Understanding Gαq/11 localization and trafficking in uveal melanoma. C.E. Randolph1, P.B. Wedegaertner1; 1Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA B1138/P1385  Wnt Signaling and Endosomal Trafficking as Regulators of Cellular Protein Degradation. L.V. Albrecht1,2, H. Kim 1,2, D. Ploper1,2, E.D. Robertis1,2; 1Howard Hughes Medical Institute, Los Angeles, CA, 2Biological Chemistry, University of California Los Angeles, Los Angeles, CA B1139/P1386  Regulation of G protein-coupled receptor signal transduction by reversible palmitoylation. J.D. Harvey1, D. Louiselle1, K. Kaltenbronn1, J. Rurik1, K.J. Blumer1; 1Cell Biology and Physiology, Washington University, St. Louis, MO B1140/P1387  G-protein signalling in the brain is regulated by arginylation-dependent degradation of RGS7 protein. M. Fina1, J. Wang1, S. Nikonov2, N.A. Leu1, S. Sterling1, N. Vardi1, A.S. Kashina1, D.W. Dong1; 1Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA, 2Department of Neuroscience, University of Pennsylvania, Philadelphia, PA B1141/P1388  High mobility group box 1 (HMGB1) is a potential regulator of huntingtin localization and function in DNA damage repair. S. Son1, R. Truant1; 1Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON

Kinases and Phosphatases 1 B1142/P1389  Investigating protein kinase rewiring in the apoptotic degradome. S.A. Zukowski1, T. Nunez de Villavicencio Díaz1, A. Rabalski1, G.A. Lajoie1, D.W. Litchfield1; 1Biochemistry, Western University, London, ON B1143/P1390  Positive regulatory role of cRaf/Mek/Erk pathway in acacetin-induced apoptosis in human acute leukemia Jurkat T cells. J. Lee1, D. Jun2, C. Kim1, G. Kwon1, Y. Kim1; 1School of Life Science and Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu 41566, Korea, South, 2Institute of Life Science and Biotechnology, Kyungpook National University, Daegu 41566, Korea, South

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MONDAY

B1120/P1367  A Method to Examine Temporal Regulation of Endogenous PostTranslational Proteoforms on Any Protein of Interest: A Snapshot of the EGFR Signaling Pathway. H. Horita1, A. Law1, S. Hong1, K. Middleton1; 1RD, Cytoskeleton Inc., Denver, CO

Monday Poster Session

Board No./Presentation No.

Monday Poster Session

B1144/P1391  Effects of Rapamycin on PYK2 and Paxillin in Jurkat T Cells. Y.J. Miyamoto1, M. Gregg1, A. Cosgel1; 1Biology, Elon University, Elon, NC

B1155/P1402  B7-H1 agonist antibodies activate p38 MAPK in activated CD8+ T cells via DNA-PKcs pathway. H. Dong1; 1Urology and Immunology, Mayo Clinic, ROCHESTER, MN

B1145/P1392  Pib2 is involved in a novel mode of TORC1-regulation. H. Ukai1, Y. Araki2, S. Kira2, T. Noda1,2; 1Graduate School of Frontier Biosciences, Osaka university, Osaka, ND, 2 Graduate School of Dentistry, Osaka university, Osaka, Japan

B1156/P1403  Dynamic regulation of Cdr1 localization and phosphorylation during osmotic stress. H.E. Opalko1, J.B. Moseley1; 1Geisel School of Medicine, Dartmouth College, Hanover, NH

B1146/P1393  A novel regulatory role of KIN1/ PAR-1/MARK kinase in fission yeast cell polarity. M.E. Lee*1, A.N. Kettenbach1, J.B. Moseley1; 1Biochemistry and Cell Biology, The Geisel School of Medicine at Dartmouth, Hanover, NH B1147/P1394  Characterization of a novel myosin light-chain kinase in C. elegans. C.A. Kelley1, E.J. Cram1; 1Biology, Northeastern University, Boston, MA B1148/P1395  Expansions of mitotic kinase families in Stentor coeruleus, the model for single cell regeneration. S.B. Reiff1, W.F. Marshall1; 1Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA B1149/P1396  Role of Abl kinases in coronavirus infection. J.M. Sisk1, C.E. Machamer1; 1Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD B1150/P1397  Regulation of m6A mRNA Modifications in Mouse Embryonic Stem Cells by Gsk-3. K.J. Faulds1, J. Egelston1, L.J. Sedivy1, C.J. Phiel1; 1Integrative Biology, University of Colorado Denver, Denver, CO B1151/P1398  Geometry sensing based on stochastic composition fluctuations in a kinase-phosphatase competitive reaction. S.D. Hansen1,2, W. Huang1,2, Y. Lee1,2, P. Bieling3, J.T. Groves1,2; 1Department of Chemistry, UC Berkeley, Berkeley, CA, 2California Institute for Quantitative Biosciences, UC Berkeley, Berkeley, CA, 3Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany B1152/P1399  A Conserved Switch Regulates Phosphatase Activity to Initiate Cell-Specific Transcription in Response to Spatial Cues. N. Bradshaw1, V.M. Levdikov2, A.J. Wlikinson2, C.M. Zimanyi1, R. Gaudet1, R. Losick1; 1Molecular and Cellular Biology, Harvard University, Cambridge, MA, 2Structural Biology Laboratory, Department of Chemistry, University of York, York, United Kingdom B1153/P1400  Calcineurin splice variant CNAβ1 is regulated by its unique C-terminus. R.K. Bond1, N. St-Denis2, A. Gingras2, M.S. Cyert1; 1Biology, Stanford, Stanford, CA, 2 Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON B1154/P1401  FBXO25 Suppress Cell Proliferation through Inhibition of ERK1/2 Phosphorylation. F.R. Teixeira1, A.O. Manfiolli1, A.C. Medeiros1, P.O. Coelho1, D. Schechtman2, M.D. Gomes1; 1Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirao Preto, Brazil, 2Department of Biochemistry, Chemistry Institute, University of São Paulo, Sao Paulo, Brazil

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B1157/P1404  Focal adhesion kinase promotes pro-inflammatory molecule expression and atherosclerosis via NF-κB activation. J.M. Murphy1, J. Kim2, E. Ahn2, S. Lim1; 1Department of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, 2Mitchell Cancer Institute, University of South Alabama, Mobile, AL B1158/P1405  Role of Endodermal Cell Signalling Inhibitors and Retinoic Acid on the Neuronal Differentiation of Mouse ES Cells. S.D. KONA1; 1Department of Biological Sciences, Southern University and AM College, Baton Rouge, LA B1159/P1406  PI(3,4,5)P3 engagement restricts Akt kinase activity to cellular membranes. M. Ebner1,2, I. Lučić1, T. Leonard1,3, I. Yudushkin1,3; 1Dept. of Medical Biochemistry, Medical University of Vienna, Vienna, Austria, 2Center for Molecular Biology, University of Vienna, Vienna, Austria, 3Dept. of Structural and Computational Biology, Max F. Perutz Laboratories, Vienna, Austria B1160/P1407  Fluorescence Imaging Shows the Effects of Tumor Suppressor INPP4B Oxidation on Akt Signaling. S. Heo1, D. Kang1; 1Life Science, Ewha Womans University, Seoul, Korea, South B1161/P1408  Fluorescent imaging shows the regulatory mechanism of local Akt activation by mTORC2. S. Kim1, D. Kang1; 1Life Science, EWHA Womans university, Seoul, Korea, South

Signaling Receptors (RTKs and GPCRs) 1 B1162/P1409  Basic residues in the cytoplasmic juxtamembrane domain of the epidermal growth factor receptor regulate receptor dimerization and signaling. J.D. Mohr1, D.A. Holowka2, B.A. Baird2; 1Molecular Medicine, Cornell University, Ithaca, NY, 2Chemistry and Chemical Biology, Cornell University, Ithaca, NY B1163/P1410  Stable binding mode of betaarrestin to GPCR reveals activation of MEK/ ERK signaling at the plasma membrane. S. Jung1, C. Kushmerick2, J. Seo3, D. Koh1, B. Hille1; 1Physiology and Biophysics, University of Washington, Seattle, WA, 2Fisiologia e Biofisica, ICB Universidade Federal de Minas Gerais, Belo Horizonte, Brazil, 3Medicine, University of California, San Diego, CA B1164/P1411  Exit of Wnt/Gpr177 from Endoplasmic Reticulum is Regulated. J. Sun1, S. Yu1, X. Zhang1, T. Daudelin2, O. Aligbe1, N. Gao1; 1Biological Sciences, Rutgers University, Newark, NJ, 2Biological Sciences, New Jersey Institute of Technology, Newark, NJ

B1165/P1412  Insulin activates the PI3K/ Akt signaling pathway in retinal pigment epithelium cells in culture. R. Salceda1, M. Sanchez-Zavaleta1; 1Neurodesarrollo y Fisiología, Universidad Nacional Autónoma de México, Mexico, D.F., Mexico B1200/P1413  Examining novel roles for Ret, PDGF, and VEGF receptor signaling in vertebrate axon extension. A. Tuttle1, M. Harding1, C. Drerup1, A. Nechiporuk1; 1Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR B1201/P1414  Bradykinin mediates the secretion of coagulation factor VIII by mouse dendritic cells via bradykinin 2 receptor (B2R) activation. C.C. Clement1, A. Follenzi2; 1Pathology, Albert Einstein College of Medicine, Bronx, NY, 2Pathology, University of Piemonte Orientale, School of Medicine, Novara, Italy B1202/P1415  Tyro3-mediated phosphorylation of ACTN4 at tyrosines is EGFRdependent to decrease the susceptibility to cleavage by m-calpain. H. Shao1; 1The Department of Pathology, University of Pittsburgh, Pittsburgh, PA B1203/P1416  Deciphering the function of the two mammalian EFR3 proteins. D.J. Tóth1, T. Balla1; 1Section on Molecular Signal Transduction, Program for Developmental Neuroscience, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD B1204/P1417  Regulation of Cardiac G-Protein Coupled Receptors in Endosomes. G.E. Peng1, M. von Zastrow2,3; 1Program in Cell Biology, University of California, San Francisco, San Francisco, CA, 2Department of Psychiatry, University of California, San Francisco, San Francisco, CA, 3Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA B1205/P1418  RON-erbB1 heterodimerization alters erbB1 endocytosis and downstream signaling. E.W. Hatch1,2, R. Grattan1,2, B.S. Wilson1,2, D.S. Lidke1,2; 1Department of Pathology, University of New Mexico, Albuquerque, NM, 2Cancer Research and Treatment Center, University of New Mexico, Albuquerque, NM B1206/P1419  The contribution of membrane associated G protein-coupled estrogen receptor 1 in nongenomic signaling by bisphenol A. L. Yu1, K. Blatchford1,2, L. Castro1, X. Gao3, J. Plair1,4, D. Dixon1; 1Molecular Pathogenesis Group, National Toxicology Program Laboratory (NTPL), Division of the NTP (DNTP), National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, 2North Carolina State University, Raleigh, NC, 3DS Technologies, Incorporated, Morrisville, NC, 4Saint Augustine’s University, Raleigh, NC B1207/P1420  Corticotropin-releasing Factor Receptor 1 and 2β form Heteromers with Distinct Cytoskeletal Interactions. B. Hasdemir1, J.A. Oses-Prieto2, A.L. Burlingame2, A. Bhargava1,3; 1The Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, CA, 2Department of Pharmacology and Chemistry, University of California San Francisco, San Francisco, CA, 3 Department of Ob-Gyn, University of California San Francisco, San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1208/P1421  Mapping the HER2 Interactome Using Extracellular Proximity-based Tagging. T.M. Thaker1,2, S. Pollock1,3, J.A. Wells1,3, N. Jura1,2; 1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 2Cardiovascular Research Institute, University of California, San Francisco, Francisco, CA, 3Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA

Signaling Networks Governing Cell Migration B1210/P1422  Connexin43 hemichannels rather than Gap junctions participate in astrocyte migration. R. Lagos-Cabré1, A. Alvarez2, A.F. Quest1, L. Leyton1; 1Cellular Communication Laboratory, Advanced Center for Chronic Diseases (ACCDiS). Center for Molecular Studies of the Cell (CEMC), Instituto de Ciencias Biomédicas, Facultad de Medicina., Universidad de Chile, Santiago, Chile, 2Faculty of Sciences, Universidad San Sebastián, Santiago, Chile

B1212/P1424  Down-regulation of MLCK promotes cell migration and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. D. Kim1, D.M. Helfman1; 1Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea B1213/P1425  The role of β-adrenergic signaling in regulation of cell deformability and motility. T. Kim1,2, E.K. Sloan1,3,4,5, A.C. Rowat2; 1Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, CA, 2Department of Integrative Biology and Physiology, University of California at Los Angeles, Los Angeles, CA, 3 Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia, 4Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Australia, 5Jonsson Comprehensive Cancer Center and AIDS Institute, University of California at Los Angeles, Los Angeles, CA B1214/P1426  VRK1 protein kinase: overexpression accelerates cell proliferation in 3D acinus cultures, retards cell migration and leads to an MET-like profile of gene expression. A.M. Mon1, P. Traktman1; 1Microbiology and Immunology, Medical University of South Carolina, Charleston, SC B1215/P1427  ADP-ribosylation factor-like 4A promotes cell migration via interacting with PAK1. K.J. Chen1, T.C. Chiang1, C.J. Yu2, F.J. Lee1,3; 1Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, 2Department of Cell and Molecular Biology, Chang Gung University, Tao-Yuan, Taiwan, 3Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan

B1216/P1428  Small molecule-mediated inhibitions of transcriptional cofactor MKL and its downstream target profilin impedes endothelial cell migration and angiogenesis. D. Gau1, W. Veon1, T. Capasso2, M.E. Joy1, B. Roman2, D. Koes3, P. Roy1,4,5; 1Bioengineering, University of Pittsburgh, Pittsburgh, PA, 2 Human Genetics, University of Pittsburgh, Pittsburgh, PA, 3Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, 4Cell Biology, University of Pittsburgh, Pittsburgh, PA, 5Pathology, University of Pittsburgh, Pittsburgh, PA

B1224/P1436  Alteration of ADM/ADM2 by hypoxia regulates migration and immunomodulation of trophoblast. C. Gu1, J. Choi1, S. Jin1, H. Jang1, J. Park2, Y. Bhang3, G. Kim1; 1Department of Biomedical Science, CHA University, Seongnam-si, Korea, South, 2 Department of Biomedical Sciences and Pharmacology, Seoul National University College of Medicine, Seoul, Korea, South, 3SeouLin Bioscience, Seongnam-si, Korea, South

B1217/P1429  Polarized cadherin fingers guide collective endothelial cell migration. A. Hayer1, L. Shao2, M. Chung1, L. Joubert3, H. Yang1, F. Tsai1, A. Bisaria1, E. Betzig2, T. Meyer1; 1Chemical and Systems Biology, Stanford University, Stanford, CA, 2Janelia Research Campus/Howerd Hughes Medical Institute, Ashburn, VA, 3Cell Sciences Imaging Facility, Stanford University, Stanford, CA

B1225/P1437  TRPM4 channels regulate migration and invasiveness of melanoma cells. D. Morales1, J. Canales1, A. Morgan1, C. Blanco1, M. Saldias1, I. Silva1, J. Rivas1, D. Riquelme2, E. Leiva-Salcedo2, M. Cáceres1, O. Cerda1; 1Programa de Biología Celular y Molecular, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile, 2Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile

B1218/P1430  Wnt5a signaling through organelle dynamics controls cell polarity and drives directional persistence in migrating melanoma cells. M.T. Connacher1,2, N. Ahn1; 1Biochemistry, University of Colorado, Boulder, CO, 2American Cancer Society, Boulder, CO

B1226/P1438  The Drosophila TNFα ortholog Eiger regulates myosin phosphorylation and cell stiffness through the Crumbs complex to facilitate embryonic macrophage tissue invasion. A. Ratheesh1, J. Vesela1, J. Biebl1, A. Gyoergy1, M. Smutny1, D. Siekhaus1; 1IST Austria, Klosterneuburg, Austria

B1219/P1431  Optogenetics-based dissection of chemotactic signaling and adaptation in neutrophils. B.R. Graziano1, D. Gong1, K.E. Anderson2, A.R. Goldberg1, O.D. Weiner1; 1Cardiovascular Research Institute, UCSF, San Francisco, CA, 2The Babraham Institute, Cambridge, United Kingdom

B1227/P1439  SHANK3 Structure Reveals a RAS-associated Domain Regulating Integrin Activation. J. Lilja1, T. Zacharchenko 2, M. Georgiadou1, H. Kreienkamp3, I. Barsukov2, J. Ivaska1; 1Turku Centre for Biotechnology, University of Turku, Turku, Finland, 2University of Liverpool, Liverpool, United Kingdom, 3 University Medical Center Hamburg-Eppendorf, Institute for Human Genetics, Hamburg, Germany

B1220/P1432  Laser-mediated ablation of zebrafish pronephric duct cells as a model to study acute kidney injury. T. Yakulov1, K. Slanchev1, M. Seifert1, S. Küchlin1, M. Schöls1, A. Bunjes1, A. Kramer-Zucker1, G. Walz1; 1Medicine, University Freiburg Medical Center, Freiburg, Germany B1221/P1433  Protein Phosphatase 1 activity promotes a collective rather than single cell mode of migration. D. Ramel1, Y. Chen2, G. Aranjuez3, A. Burtscher3, K. Sawant2,3, M. Lawas2, X. Wang1, J.A. McDonald2; 1LBCMCP, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Toulouse, France, 2 Division of Biology, Kansas State University, Manhattan, KS, 3Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH B1222/P1434  Active Moesin regulates the formation of a supracellular actin structure restricting the formation of protrusions during the migration of cell clusters. C. Plutoni1, S. Keil1, S. Carreno1, P.P. Roux1, G. Emery1; 1IRIC / University of Montreal, Montreal, QC B1223/P1435  Placenta derived mesenchymal stem cells increase invasion ability of trophoblast via enhancing mitochondrial function. J. Seok1, C. Gu1, J. Choi1, H. Jeong1, G. Kim1; 1Biomedical Science, CHA University, Seongnam, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1228/P1440  Role of PI3K/Akt2 on MCF10A cell migration induced by extracellular vesicles from MDA-MB-231 breast cancer cells stimulated with linoleic acid. E. LealOrta1, J. Ramirez-Ricardo1, O. Hernandez1, P. Cortes-Reynosa1, E.P. Salazar1; 1Biologia Celular, Cinvestav-IPN, Mexico City, Mexico B1229/P1441  Plasma Membrane PI(4,5)P2 Levels Regulate Excitability During Changes in Cellular Morphology. C.J. Janetopoulos1, D. Jowhar1, G. Wright1, M. Housman1, H. Mohammed1, M. Beshay1, N. Bawazir1, B. Chen1, E. Betzig1, R. Khodadai1; 1BIological Sciences, University of the Sciences, Philadelphia, PA B1230/P1442  FGFR2 activating mutations potentiate migration and invasion in endometrial cancer cells. R. Ju1,2, M.N. Adams1,2, S.J. Stehbens1,2, P.M. Pollock1,2; 1Translational Research Institute Australia (TRI), Brisbane, Australia, 2 Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology (QUT), Brisbane, Australia B1231/P1443  Effects of Substance P on proliferation and migration of normal and diabetic dermal fibroblasts. J. Yu1, N. Jung1, K. Park2, Y. Son1; 1Graduate School of Biotechnology, Kyung Hee University, Seoul, Korea, South, 2East-West Medical Research Institute, Kyung Hee University, Seoul, Korea, South

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B1211/P1423  Regulation of Epithelial Migration by Epithelial Cell Adhesion Molecule (EpCAM). A. Barth1, H. Kim1, I. RiedelKruse1; 1Bioengineering, Stanford University, Stanford, CA

Monday Poster Session

Board No./Presentation No.

Cytoskeleton-Membrane Interactions B1232/P1444  How do septins interact with lipids and deform membranes? A. Bertin1, C. Taveneau1, A. Beber1, D. Levy1, A. Di cicco1, s. mangenot1, P. Milhiet2, M. Mavrakis3; 1PCC, Institut Curie, Paris, France, 2CBS, CNRS, Montpellier, France, 3Institut Fresnel, CNRS, Marseille, France B1233/P1445  Cellular, molecular and structural mechanisms of phosphorylation-dependent inhibition of IRSp53 by 14-3-3. D.J. Kast1, R. Dominguez1; 1Physiology, University of Pennsylvania, Philadelphia, PA B1234/P1446  Role of the coiled-coil domain of septins in membrane binding and geometry recognition. K. Cannon1, A. Bridges2, M. Garten3, J. Zimmerberg3, A.S. Gladfelter 1 1 ;  Biology, University of North Carolina at Chapel Hill, 27516, NC, 2Biology, Dartmouth College, Hanover, NH, 3Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD B1235/P1447  Ezrin recruitment in curved membrane regions. F. Tsai1, A. Bertin1, S. Miserey-Lenkei2, H. Bousquet2, L. Picas3, B. Goud2, E. Coudrier2, P. Bassereau1; 1UMR 168, Institut Curie, PSL Research University, and CNRS, Paris, France, 2UMR 144, Institut Curie, PSL Research University, and CNRS, Paris, France, 3CNRS UMR 5048 and INSERM U1054, Centre de Biochimie Structurale, CNRS, INSERM and Université de Montpellier, Montpellier, France B1236/P1448  Role of cytoskeleton in morphological changes of blood platelets. A. Mathur1, S. Dmitrieff1, S. Correia1, R. Gibeaux1,2, I. Kalinina1, T. Quidwai1, J. Ries1, F. Nedelec1; 1Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany, 2Department of Molecular Cell Biology, University of California, Berkeley, CA B1237/P1449  The desmosome/intermediate filament linkage regulates cell mechanics. J.A. Broussard1,2, R. Yang3, C. Huang3, S. P. Nathamgari3, A.M. Beese3, L.M. Godsel1, S. Lee1, F. Zhou3, N.J. Sniadecki4, H.D. Espinosa3,5, K.J. Green1,2; 1Department of Pathology, Northwestern University, Chicago, IL, 2Department of Dermatology, Northwestern University, Chicago, IL, 3Department of Mechanical Engineering, Northwestern University, Evanston, IL, 4 Departments of Mechanical Engineering and Bioengineering, University of Washington, Seattle, WA, 5Theoretical and Applied Mechanics Program, Northwestern University, Evanston, IL B1238/P1450  Study Cell Elasticity in Different Directions Using Atomic Force Microscopy (AFM) and Microfluidic Devices. C. Wang1, C. Lin2, C. Peng2, W. Liao2, Y. Tung2; 1Civil Engineering, Tamkang University, New Taipei City, Taiwan, 2Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan B1239/P1451  A Podosome Scaffold Protein Tks5 Regulates Dynamin-2 to Promote Myoblast Fusion. M. Chuang1, Y. Liu1; 1Insititute of Molecular Medicine, National Taiwan University, Taipei, Taiwan

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Monday Poster Session B1240/P1452  Molecular mechanisms of membrane remodeling during regulated secretion in live animals. A. Shitara1, O. Milberg2, M.S. Tora1,2, S. Ebrahim1, R. Weigert1; 1Laboratory of Cellular and Molecular Biology, National Cancer Institute, Center for Cancer Research, Bethesda, MD, 2Intracellular Membrane Trafficking Section, National Institute of Dental and Craniofacial Research, Bethesda, MD B1241/P1453  The Drosophila ortholog of Sorting nexin 9 is required for egg chamber development and border cell migration. L.J. Hicks1, G.B. Gonsalvez1; 1Cellular Biology and Anatomy, Augusta University, Augusta, GA B1242/P1454  CD2AP is a novel regulator of the mechanosensitive adhesion receptor ICAM-1 and Rac1 activity to control leukocyte transmigration. A. Schaefer1,2, T. van Duijn3, J. Majolee3, K. Burridge1,2, P.L. Hordijk3,4; 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Dept.of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Dept. of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, University of Amsterdam, Amsterdam, Netherlands, 4Dept. of Physiology, VU University Medical Center, Amsterdam, Netherlands B1243/P1455  Apoptotic forces in tissue morphogenesis. B. Monier1, M. Gettings1, A. Ambrosini1, T. Mangeat1, S. Schott1, M. Suzanne1; 1Univ de Toulouse, CNRS, UPS, LBCMCP, CBI, Toulouse, France B1244/P1456  Septins form rigid films on model biomembranes that slow down lipid diffusion. A. Szuba1, N. Aissaoui2, A. Bertin3, R. Richter2, M. Mavrakis4, G. Koenderink1; 1Biological Soft Matter, FOM Institute AMOLF, Amsterdam, Netherlands, 2Biosurfaces Lab, CIC biomaGUNE, San Sebastian, Spain, 3Institute Curie, Paris, France, 4Aix Marseille Univ, CRNS, Centrale Marseille, Institut Fresnel, Marseille, France B1245/P1457  Role of GTP in septin assembly and dynamics. A. Khan1, A.S. Gladfelter1; 1Biology, Dartmouth College, Hanover, NH B1246/P1458  Noninvasive acoustic force spectroscopy for measuring apical surface membrane tension and intercellular adhesive forces in polarized epithelium. A.X. Cartagena-Rivera1, C.M. Van Itallie2, J.M. Anderson2, R.S. Chadwick1; 1National Institute on Deafness and Other Communications Disorders, National Institutes of Health, Bethesda, MD, 2National Hearth, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD B1247/P1459  The number distribution of elastic modulus of brewery yeast investigated by atomic force microscopy. R. Tanaka1, R. Aritomo2, T. Shioi2, T. Okajima1; 1Graduation school of information science and technology, Hokkaido University, Sapporo, Japan, 2Sapporo Breweries LTD, Eniwa, Japan

Cadherins and Cell-Cell Interactions B1249/P1460  A role for NF-protocadherin in ventral motor neuron differentiation in Xenopus. P. Puettmann1, R. Bradley1; 1Cell Biology and Neuroscience, Montana State University, Bozeman, MT B1250/P1461  Endogenous Sheet Tension within a Symmetric Epithelial Cell Colony is Anisotropic. V. Maruthamuthu1, S. Dumbali1; 1Mechanical & Aerospace Engineering, Old Dominion University, Norfolk, VA B1251/P1462  CTLA-4 expressed in human breast cancer cells exerts pN-scale forces to displace its ligand CD80. S. Park1, L. Cruz2, L. Lin2, B. Kim3, M. Jo3, T. Ha3, L. Lu2, Y. Chen1; 1Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 2Biological Sciences, University of California-San Diego, San Diego, CA, 3Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD B1252/P1463  Roles of the E-cadherin/BetaCatenin Complex in the Mechanical Induction of Epithelium-to-Mesenchyme Transition. C. Gayrard1, C. Bernaudin1, C. Seiler1, N. Borghi1; 1CNRS UMR7592, Institut Jacques Monod / Université Paris 7, Paris, France B1253/P1464  Rigidity-dependent E-cadherin adhesion activates distinct GTPase and actin assembly pathways to initiate and expand cell-cell contacts. C. Collins1, W.J. Nelson1; 1Biology, Stanford University, Stanford, CA B1254/P1465  Mechanical force across Ecadherin regulates homeostasis of epithelial acini. D.E. Conway1, V. Narayanan1; 1Biomedical Engineering, Virginia Commonwealth University, Richmond, VA B1255/P1466  The Mechano-Responsive Ecadherin/LGN Complex Instructs Epithelial Cell Division Orientation. M. Gloerich1, K.C. Hart1, J.M. Bianchini1, K.A. Siemers1, D.J. Cohen1, J. Tan2, J. Sim3, B.L. Pruitt3,4,5, W.J. Nelson1,4; 1Biology, Stanford University, Stanford, CA, 2Biophysics Program, Stanford University, Stanford, CA, 3Mechanical Engineering, Stanford University, Stanford, CA, 4Molecular and Cellular Physiology, Stanford University, Stanford, CA, 5Bioengineering, Stanford University, Stanford, CA B1256/P1467  E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape. K.C. Hart1, J. Tan2, K.A. Siemers1, J. Sim3, M. Gloerich4, W.J. Nelson1; 1Biology, Stanford University, Stanford, CA, 2Biophysics, Stanford University, Stanford, CA, 3Mechanical Engineering, Stanford University, Stanford, CA, 4Molecular Cancer Research, UMC Utrecht, Utrecht, Netherlands B1257/P1468  Platform for Modeling Intercellular Binding Forces Using a Novel CellStretcher. J. Kim1, C. Lin2, Y. Chen1; 1Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 2Mechanical Engineering, Texas AM, College Station, TX B1258/P1469  The Role of Vinculin in Cardiomyocyte Adhesion and Mechanical Continuity. C.D. Merkel1, R.M. O’Dowd1, A.V. Kwiatkowski1; 1Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1259/P1470  Adhesion and Fusion of Muscle Cells are Promoted by Filopodia. D. Segal1, N. Dhanyasi1, E.D. Schejter1, B. Shilo1; 1Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

B1261/P1472  TRIP6 inhibits the Hippo signaling pathway in response to tension at cellcell junctions. S. Dutta1, S. Mana-Capelli1, D. McCollum1; 1Biochemistry, University of Massachusetts Medical School, Worcester, MA B1262/P1473  Positioning a neuron-glia attachment site through localized cell adhesion. I.G. McLachlan1,2, E.R. Lamkin1,2, M.G. Heiman1,2; 1Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, 2Department of Genetics, Harvard Medical School, Boston, MA B1263/P1474  N-cadherin strengthens VEcadherin adhesion through a Rac1/Trio signaling axis. K.J. Kruse1, F. Huang1, Y. Sun1, S.M. Vogel1, A.B. Malik1, Y.A. Komarova1; 1Pharmacology, University of Illinois at Chicago, Chicago, IL B1264/P1475  Twist1+ epithelial cells retain adhesive and proliferative capacity throughout dissemination. E.R. Shamir1,2, K. Coutinho2,3, D. Georgess2, M. Auer3, A.J. Ewald2; 1Pathology, University of California, San Francisco, San Francisco, CA, 2Cell Biology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA B1265/P1476  Epidermal growth factor receptor is required for E-cadherin force transduction. D. Leckband1, P. Sehgal1, I. Muhamed2, J. Wu1, X. Kong2; 1Chemical Sciences, University of Illinois, Urbana, IL, 2Biochemistry, University of Illinois, Urbana, IL B1266/P1477  Study of epithelial-mesenchymal transition markers in mammary epithelial cells MCF10A in response to collagen type I. A. Garcia-Hernandez1, R. Diaz-Aragon1, P. Cortes-Reynosa1, E.P. Salazar1; 1Biología Celular, Cinvestav-IPN, MEXICO, Mexico

B1267/P1478  Eucalyptol ameliorates high glucose-induced epithelial to mesenchymal transition and renal tubulointerstitial fibrosis. D. Kim1, M. Kang1, Y. Kang1; 1Department of Food Science and Nutrition, Hallym University, Chuncheon, Kangwon-do, Korea, South B1268/P1479  Regulation of Adhesion Proteins During Choroid Fissure Closure in Zebrafish. A. Smith1, A.E. James1; 1Biology Department, University of Northern Colorado, Greeley, CO B1269/P1480  Visualization of cell-cell interactions dynamics in early Xenopus embryos reveals direct interaction between PAPC and XCC at the gastrula stage. F.B. Riquet1,2,3,4, F. Sipieter1,2,4, A. Leray5,6, C. Spriet3,5, H. Badache4,7, D. Vicogne3,4, L. Heliot5,8, Y. Saka4,9; 1Molecular Signaling and Cell Death Unit, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium, 2Molecular Signaling and Cell Death Unit, Inflammation Research Center (IRC), a VIB-UGent department, VIB, Ghent, Belgium, 3Structural and Functional Glycobiology Unit (UGSF), CNRS UMR 8576, Lille 1 University, Villeneuve d’Ascq, France, 4Multicellular Dynamics group, Interdisciplinary Research Institute of Lille, CNRS IRI USR 3078, CNRS/Lille1 University, Villeneuve d’Ascq, France, 5Equipe Biophotonique Cellulaire Fonctionnelle, Interdisciplinary Research Institute of Lille, CNRS IRI USR 3078, CNRS/Lille1 University, Villeneuve d’Ascq, France, 6Laboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS,, CNRS/Université Bourgogne Franche-Comté, Dijon, France, 7Service TP Biologie cellulaire, Département de Biologie, Université Paris Sud, Orsay, France, 8Team Biophotonique Cellulaire Fonctionnelle, Laboratoire de Physique des Lasers, Atomes et Molécules (PhLAM), CNRS UMR 8523, CNRS/Lille1 University, Villeneuve d’Ascq, France, 9Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom B1270/P1481  Alpha-T-catenin Ligand Interactions and Their Regulation by Phosphorylation. J.A. Heier1, I.W. Dale1, C.D. Merkel1, A.V. Kwiatkowski1; 1Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA

Glycoproteins, Invadosomes, and Remodeling B1271/P1482  Identification of a novel Cripto/ Myosin II interaction that promotes stem cell mediated tissue regeneration. M. Hoover1, E. Duell1, E. Booker2, B. Williams1, C. Arellano-Garcia1, W. Fischer2, P. Gray2, J.A. Kelber1; 1Biology, California State University Northridge, Northridge, CA, 2Clayton Foundation for Peptide Biology, The Salk Institute, La Jolla, CA B1272/P1483  Membrane-bound thrombomodulin interacts with fibronectin to regulate angiogenesis. H. Wu1, Y. Shu1, G. Shi1; 1Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1273/P1484  Migration through Hyaluronic Acid Matrices is Supported by CD44dependent Microtentacles. K.J. Wolf1,2, S.J. Kenny3, K. Xu3,4, S. Kumar1,2,5; 1Bioengineering, University of California, Berkeley, Berkeley, CA, 2Bioengineering, UC Berkeley - UCSF Graduate Program, Berkeley, CA, 3Chemistry, University of California, Berkeley, Berkeley, CA, 4Division of Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, 5Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA B1274/P1485  Hic-5 regulation of invadopodia rosette formation and organization. A.C. Gulvady1, C.E. Turner1; 1Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY B1275/P1486  Active mRNA translation into invadosomes revealed by combination of laser capture and proteomic analysis. Z. Ezzoukhry1, f. Cordelières2, J. Dupuy3, M. Maitre3, V. Moreau1, A. Raymond4, F. Saltel1; 1U1053, INSERM, Bordeaux, France, 2UMS 3420 CNRS, bordeaux, France, 3Neurocentre Magendie, Bordeaux, France, 4U1035, Inserm, Bordeaux, France B1276/P1487  Extracellular matrix malleability regulates breast cancer cell invasion. K.M. Wisdom1, R.M. Desai2, D.J. Mooney2, O. Chaudhuri1; 1Mechanical Engineering, Stanford University, Stanford, CA, 2School of Engineering and Applied Sciences, Harvard University, Cambridge, MA B1277/P1488  Human neutrophils secrete MMP-9 and MMP-8 during adhesion to fibronectin in the presence of insulin. S.I. Galkina1, N.V. Fedorova1, M.V. Serebryakova1, L.A. Baratova1, G.F. Sud’ina1; 1Belozersky institute, Lomonosov Moscow State University, Moscow, Russia

Structure and Function of the Extracellular Matrix B1278/P1489  Understanding the Mechanics of Adhesion Dependent and Independent Neutrophil Migration in Three-Dimensional Extra-Cellular Matrices. J.J. François1, J.C. Del Alamo2, R.A. Firtel3, J. Lasheras2; 1Bioengineering, University of California, San Diego, La Jolla, CA, 2Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, CA, 3Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA B1279/P1490  Identification of laminin α5 short arm peptides active for endothelial cell attachment and tube formation. Y. Sugawara1; 1Clinical Biochemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan B1280/P1491  Novel Role of Septin2 in Endothelial Cell Podosome Formation and Matrix Degradation. K.B. Collins1, H. Kang1, J. Klomp1, A.V. Karginov1, A.B. Malik1; 1Molecular and Cellular Pharmacology, University of Illinois at Chicago, Chicago, IL

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B1260/P1471  Nanoscale architecture of cadherin-based cell adhesions. C. Bertocchi1, Y. Wang1, A. Ravasio1, Y. Hara1, Y. Wu1, T. Sailov2, M.A. Baird3, M.W. Davidson4,5, R. Zaidel-Bar1,6, Y. Toyama1,7,8, B. Ladoux1,9, R. Mege9, P. Kanchanawong1,6; 1Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 2Singapore Centre on Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore, 3National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 4National High Magnetic Field Laboratory, The Florida State University, Tallahassee, FL, 5 Department of Biological Science, The Florida State University, Tallahassee, FL, 6Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore, 7Department of Biological Sciences, National University of Singapore, Singapore, Singapore, 8Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore, 9Institut Jacques Monod, Université Paris Diderot and CNRS, Paris, France

Monday Poster Session

Board No./Presentation No. B1281/P1492  Remodeling and internalization of the hyaluronan-dependent pericellular matrix during adipogenic differentiation of 3T3-L1 cells. S.S. Sellers1, C.B. Knudson1; 1Anatomy and Cell Biology, East Carolina University, Greenville, NC B1282/P1493  Small mineralized crystals formed by osteogenic cells in 3D collagen gel culture. C. Umezu1; 1Graduate of Environmental Engineering, The University of Kitakyushu, Fukuoka, Japan B1283/P1494  Expression of Osteopontin in Human Fetal Osteoblast Cells (hFOB1.19) After Graphene Oxide, Folate and Copper Sulfide Nanoparticle Treatment. S.C. Gonzales1, E.C. Regisford1, L. Carson Ph.D1, A. Oki1, D. Gilbert1, H. Roberson1, J. Lewis2; 1Chemistry, Prairie View AM University, Prairie View, TX, 2Biology, Prairie View AM University, Prairie View, TX B1284/P1495  Effects of Sex Hormones and Prolactin on Matrix Deposition and Expression of Pro-Inflammatory Factors by Corneal Fibroblasts. T. McKay1, D. Karamichos1,2; 1Cell Biology, University of Oklahoma Health Sciences Center, Norman, OK, 2Ophthalmology, Dean McGee Eye Institute, Oklahoma City, OK B1285/P1496  Dynamics of ECM based in vitro microfluidic vessels in response to physical perturbations. D. Maity1, D. Vig2, A. Wong3, Y. Chen2,4, S. Sun2; 1Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 2Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 3Materials Science Engineering, Johns Hopkins University, Baltimore, MD, 4Centre for Cell Dynamcis, Johns Hopkins University, Baltimore, MD B1286/P1497  The role of fibroblast-specific canonical TGFb signaling in cardiac fibrosis. H. Khalil1, O. Kanisicak1, J.D. Molkentin1; 1Cardiovascular Biology, Cincinnati Children’s Hospital, Cincinnati, OH B1300/P1498  Crosslinking enzyme Tissue Transglutaminase 2 elevates Intraocular Pressure in mice. U. Raychaudhuri1, C. Millar1, C.M. McDowell1, A.F. Clark1; 1Visual Sciences, University of North Texas Health Science Center, Fort Worth, TX B1301/P1499  Evolution of collagen IV and basement membrane enabling multicellularity. A.L. Fidler1, S.V. Chetyrkin1, C.E. Darris1, V.K. Pedchenko1, S.P. Buodko1, W.G. Jerome2, J. Hudson3, A. Rokas4, B.G. Hudson1; 1Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 3Medical Education and Administration, Vanderbilt University Medical Center, Nashville, TN, 4Biological Sciences, Vanderbilt University Medical Center, Nashville, TN B1302/P1500  Imbalance of matrix metalloproteinase in the obesity-associated asthma. C.P. Vieira1, L.P. Oliveira2, M.B. da Silva2, D.M. André1, E.B. Tavares1, E.R. Pimentel2, E. Antunes1; 1Pharmacology, State University of Campinas, Campinas, Brazil, 2Structural and Functional Biology, State University of Campinas, Campinas/SP, Brazil

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Monday Poster Session B1303/P1501  Regulation of larval zebrafish wound healing through the formation of collagen projections. D.C. LeBert1, J. Squirrell2, C. Freisinger1, K. Eliceiri2, A. Huttenlocher1; 1Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, 2Laboratory for Optical and Computational Instrumentation, University of Wisconsin-Madison, Madison, WI B1304/P1502  Biophysical properties of the corneal stroma influence apoptosis of myofibroblasts. I. Jalilian1, A. Robinson1, V. Raghunathan2, J. Sermeno1, S. Muppala1, S.M. Thomasy1, C.J. Murphy1,3; 1Department of Surgical Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA, 2The Ocular Surface Institute, College of Optometry, University of Houston, Houston, TX, 3Department of Ophthalmology Vision Science, School of Medicine, University of California, Davis, Davis, CA B1305/P1503  A peptide, P1, from the extracellular matrix glycoprotein fibronectin, enhances growth factor driven angiogenesis. M.M. McTigue1, M.G. Tonnesen2,3, R.A. Clark1,3; 1Biomedical Engineering, Stony Brook University, Stony Brook, NY, 2Dermatology, Northport Veterans Affairs Medical Center, Northport, NY, 3Dermatology, Stony Brook University, Stony Brook, NY B1306/P1504  Impaired PV and PNN expression in CA1 hippocampus may underlie contextual recall deficits after auditory fear conditioning in FMR1 knockout mice. S. Afroz1, S. Reinhard2,3, K. Pendi1, Y. Hanania1, K. Razak3, I.M. Ethell1; 1Biomedical Sciences, UCR, Riverside, CA, 2Neuroscience Graduate Program, UCR, Riverside, CA, 3Psychology, UCR, Riverside, CA B1307/P1505  Simvastatin improves gait recovery and tendon healing after partial tenotomy. L.P. Oliveira1, C.P. Vieira2, F.D. Guerra3, G.F. Simões1, A.L. Oliveira1, E.R. Pimentel1; 1Department of Structural and Functional Biology, University of Campinas, Campinas, Brazil, 2Department of Pharmacology, University of Campinas, Campinas, Brazil, 3 Department of Anatomy, Federal University of Alfenas, Alfenas, Brazil

Chaperones, Protein Folding, and Quality Control 2 B1309/P1506  Fic-mediated AMPylation of the ER chaperone BiP is required to maintain visual neurotransmission. A.T. Moehlman1, A.K. Casey2, J. Zhang2, K. Orth2,3, H. Kramer1,4; 1Neuroscience, UT Southwestern Medical Center, Dallas, TX, 2Molecular Biology, UT Southwestern Medical Center, Dallas, TX, 3 Howard Hughes Medical Institute, Dallas, TX, 4Cell Biology, UT Southwestern Medical Center, Dallas, TX B1310/P1507  Detection of ER stress markers in laminitic lamellar tissue from horses with endocrinopathy-associated laminitis. L. Cassimeris1, H. Galantino-Homer2; 1Biological Sciences, Lehigh University, Bethlehem, PA, 2 Clinical Studies, University of Pennsylvania School of Veterinary Medicine, New Bolton Center, Kennett Square, PA

B1311/P1508  The Sec61 translocon controls IRE1 activity during the unfolded protein response. A. Sundaram1, R. Plumb1, S. Appathurai1, M. Mariappan1; 1Department of Cell Biology, Nanobiology Institute, Yale University, West Haven, CT B1312/P1509  A conformational RNA zipper promotes non‐conventional XBP1 mRNA splicing. J. Peschek1, D. Acosta-Alvear1, A.S. Mendez1, P. Walter1; 1Department of Biochemistry and Biophysics, UC San Francisco/HHMI, San Francisco, CA B1313/P1510  An unfolded protein-induced conformational switch activates mammalian IRE1. G. Karagöz1, V. Chen1,2, J. Schaefer1,3, P. Walter1; 1Department of Biochemistry and Biophysics, University of California, San Francisco/ HHMI, San Francisco, CA, 2Department of Plant Biology, Carnegie Institution for Science, Stanford, CA, 3Center for Molecular Biology, University of Heidelberg, Heidelberg, Germany B1314/P1511  The unfolded protein response and protein targeting to the endoplasmic reticulum converge on the stress sensor IRE1. D. Acosta-Alvear1,2, G. Karagöz2, F. Fröhlich3,4, T. Walther3, P. Walter2; 1Current address: Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, 2Department of Biochemistry and Biophysics and Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, 3 Harvard School of Public Health and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, 4Current address: Molecular Membrane Biology (SFB Research Group), Universität Osnabrück, Osnabrück, Germany B1315/P1512  The mitochondrial Lon protease is an adaptive, stress-responsive, proteinase whose induction is both sex- and age-dependent in D. melanogaster. L. Corrales-Diaz Pomatto1, S. Wong1, J. Tower1,2, K. J.A. Davies1,2; 1Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 2Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA B1316/P1513  Quality control of protein folding in the cytosol. S.N. Chan1,2, R. Prasad2, D. Ng1,2; 1NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore (NUS), Singapore, Singapore, 2Cell Stress and Homeostasis, Temasek Life Sciences Laboratory (TLL), Singapore, Singapore B1317/P1514  Dimethyl Sulfoxide-derived ROS Impairs Preimplantation Embryo Development via Accumulation of Ca2+ and ER Stress in Mice. M. Kang1, D. Um1, S. Kim1, Y. Choi1, J. Kim1; 1Department of Stem Cell and Regenerative Biology, Konkuk University, Seoul, Korea B1318/P1515  Sigma 1 Receptors Modulate Endoplasmic Reticulum Stress Response to Tunicamycin Treatment. N. Ahlskog1, L.A. Tassé1, M.J. Abraham1, P. Chudalayandi2, A.Y. Wong2, J.K. Ngsee1,2, R. Bergeron1,2; 1Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, 2Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON

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Board No./Presentation No. B1319/P1516  Characterization of cell-type specific responses to misfolded protein stress in C. elegans. C. Gormley1, K. Hoffman1, R. Ihsan1, T. Bloss1; 1Biology, James Madison University, Harrisonburg, VA B1320/P1517  Impaired recovery from ER stress in Mouse Embryonic Fibroblasts lacking the Sigma-1 receptor. L.A. Tassé1, P. Chudalayandi1, N. Ahlskog1, M.J. Abraham1, K.L. Ferguson1, J. Ngsee1,2, A.Y. Wong2, R. Bergeron1,2; 1Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, 2Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON B1321/P1518  Survive or die drying: investigating the roles of Hsp12 and trehalose in desiccation tolerance. S.X. Kim1, G. Camdere1, D.E. Koshland1, H. Tapia1; 1Molecual and Cell Biology, University of California, Berkeley, Berkeley, CA B1322/P1519  Dissecting the decision points in secretory pathway protein quality control. B.S. Park1, P. Satpute-Krishnan2; 1Undergraduate Bioinformatics Program, Baylor University, Waco, TX, 2Biochemistry and Molecular Biology, Uniformed Services University, Bethesda, MD

B1324/P1521  Overexpression of Nuclear Protein Localization-3 Induces Intracellular Prion-Like Aggregates in Saccharomyces cerevisiae. D.P. Bracho-Rincon1, I. SerranoLachapel1, L.E. Martinez-Rodriguez1, C.I. Gonzalez-Vargas1; 1Biology, University of Puerto Rico-Río Piedras, San Juan, PR B1325/P1522  Secretion of the Neuroprotective J Protein, Cysteine String Protein. J. Braun1; 1Department of Biochemistry, University of Calgary, Calgary, AB

Ubiquitin and Proteasome Function B1326/P1523  Sexual Dimorphism and the 20S Proteasome in Oxidative Stress and Adaptive Homeostasis. S. Wong1, L. Corrales-Diaz Pomatto1, J. Tower1,2, K. J.A. Davies1,2; 1Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, 2 Molecular and Computational Biology USC Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, CA B1327/P1524  Oxidative stress in mitochondria of TKD adipocytes may increase histone carbonylation in nuclei via retrograde signaling. M.L. Hart1, A. Hauck1, D.A. Bernlohr1; 1Biochemistry, Molecular Biology, Biophysics, University of Minnesota, Minneapolis, MN

B1328/P1525  SCFSlmb mediates degradation of SMN monomers. K.M. Gray1, Y. Wen2, K. Kaifer3, C. Lorson4, A.G. Matera1,2; 1Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, 2Department of Biology, University of North Carolina, Chapel Hill, NC, 3Molecular Pathogenesis and Therapeutics Graduate Program, University of Missouri, Columbia, MO, 4Molecular Microbiology Immunology, University of Missouri, Columbia, MO B1329/P1526  Role of Cullin activities in skeletal muscle development. J. Blondelle1, P. Shapiro1, S. Lange1; 1School of Medicine, Division of Cardiology, University of California, San Diego, San Diego, CA B1330/P1527  Understanding regulated degradation of CEBPB in early adipogenesis. P. Gupta1, K.M. Kovary1, M.N. Teruel1; 1Chemical and Systems Biology, Stanford University, Stanford, CA B1331/P1528  The pseudophosphatase STYX regulates SCF-FBW7. V. Reiterer1, H. Farhan1, C. Behrends2, P. DiFiore3; 1Molecular medicine, University of Oslo, Oslo, Norway, 2Biochemistry, University of Frankfurt, Frankfurt, Germany, 3 IFOM, Milano, Italy B1332/P1529  Regulation of two neural receptors by ERAD E3 ubiquitin ligases in C. elegans. L.L. Dahlberg1, S. Witus1,2, A. Townsend1; 1Biology, Western Washington University, Bellingham, WA, 2Biochemistry, University of Washington, Seattle, WA B1333/P1530  Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation. M. To1, C.W. Peterson1, M.A. Roberts1, J.L. Counihan1,2,3, T.T. Wu1, M.S. Forster1, D.K. Nomura1,2,3, J.A. Olzmann1; 1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, CA, 2Department of Chemistry, University of California, Berkeley, CA, 3Department of Molecular and Cell Biology, University of California, Berkeley, CA B1334/P1531  Tau oligomer post-translational modification and the dysregulation of the proteasome in Alzheimer’s disease. A.N. Nilson1,2, J. Deger1,2, J.E. Gerson1,2, R. Kayed1,2; 1Neuroscience, University of Texas Medical Branch, Galveston, TX, 2Neurology, Mitchell Center for Neurodegenerative Diseases, Galveston, TX B1335/P1532  Identification of novel regulators of Amyloid Precursor Protein by High Content Imaging siRNA Screening. H.A. Bustamante1, Y.I. Cheuquemilla1, G.E. Valenzuela 2, G.A. Mardones1,3, A. Rojas-Fernandez3, R.T. Hay4, P.V. Burgos1,3; 1Physiology Department, Universidad Austral de Chile, Valdivia, Chile, 2Biochemistry and Microbiology Department, Universidad Austral de Chile, Valdivia, Chile, 3Centro Interdisciplinario de Estudios del Sistema Nervioso (CISNe), Universidad Austral de Chile, Valdivia, Chile, 4College of Life Sciences, University of Dundee, Dundee, United Kingdom B1336/P1533  Modulation of SQSTM1 activity by UBA domain ubiquitination. Y. Lee1, T. Chou2, C.C. Weihl1; 1Neurology, Washington University in St. Louis, St. Louis, MO, 2 Pediatrics, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, CA

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B1337/P1534  Activation of WW-HECT ubiquitin ligases by substrate clustering. T. Mund1, H. . Pelham1; 1Cell Biology, MRC, Laboratory of Molecular Biology, Cambridge, United Kingdom

Computational Cell Biology and Bioinformatics B1339/P1535  Population dynamics of mitochondria in mammalian cells. K. Kornick1, M. Das1; 1Physics and Astronomy, Rochester Institute of Technology, Rochester, NY B1340/P1536  A generalized mathematical framework to model diffusion in curved surfaces reveals geometry-based cargo sorting in membrane tubules. C.J. Klaus1, K. Raghunathan2, E. DiBenedetto1,2, A.K. Kenworthy2,3; 1Department of Mathematics, Vanderbilt University, Nashville, TN, 2Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 3Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN B1341/P1537  Computational Drug Design of Nucleotide Excision DNA Repair Inhibitors for Improved Cancer Therapy. F. Gentile1, J.A. Tuszynski1,2, K.H. Barakat3; 1Physics, University of Alberta, Edmonton, AB, 2Oncology, University of Alberta, Edmonton, AB, 3Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB B1342/P1538  In-silico assessment of phytochemicals as dengue virus E protein inhibitors. M. Ahmed1, S.S. Malik1; 1Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan B1343/P1539  Brownian ratchet mechanism of plasmid segregation. L. Hu1, A.G. Vecchiarelli2, K. Mizuuchi2, K.C. Neuman1, J. Liu1; 1National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 2 National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD B1344/P1540  Multi-label prediction of subcellular localization in confocal images using deep neural networks. C.F. Winsnes1, D.P. Sullivan1, K. Smith2, E. Lundberg1; 1Biotechnology, Science for Life Laboratory (KTH), Solna, Sweden, 2Computer Science and Communications, Science for Life Laboratory (KTH), Solna, Sweden B1345/P1541  SourceData: a semantic platform to make data and figures discoverable. T. Lemberger1, N. George1, R. Liechti2, L. Götz2, S. El-Gebali1, I. Crespo2, I. Xenarios2; 1EMBO, Heidelberg, Germany, 2Vital-IT Swiss-Prot, Swiss Institute of Bioinformatics, Lausanne, Switzerland B1346/P1542  Annotations of Important Biological Processes in Domesticated and Endangered Animals. C.B. Steemer1, D. Grogan1, L. Carson Ph.D1, G. Regisford Ph.D2, J. Hu Ph.D3; 1Agriculture, Prairie View AM University, Prairie View, TX, 2Biology, Prairie View AM University, Prairie View, TX, 3Biochemistry, Texas AM University, College Station, TX

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MONDAY

B1323/P1520  80S ribosome-binding proteins link translation arrest to nascent chain degradation. C.S. Sitron1, J.H. Park1, O. Brandman1; 1Department of Biochemistry, Stanford University, Stanford, CA

Monday Poster Session

Board No./Presentation No. B1347/P1543  Using Bioinformatics to Characterize the Novel Gene, KIAA1586. A.J. Green1, D. Ritter, PhD1, E.C. Regisford1; 1Biology, Prairie View AM University, Prairie View, TX B1348/P1544  GeneLab: Scientific partnerships and an open-access database to maximize usage of omics data from space biology experiments. S.S. Reinsch1, J.M. Galazka1, D.C. Berrios1,2, K. Chakravarty1,3, H. Fogle1,4, S. Lai1,5, V. Boyko1,5, L.R. Timucin1,2, P.B. Tran1, M. Skidmore1; 1Space Biosciences Division, NASA-Ames Research Center, Moffett Field, CA, 2University Affiliated Research Center, Moffett Field, CA, 3Logyx LLC, Moffett Field, CA, 4Bionetics, Moffett Field, CA, 5Wyle Labs, Moffett Field, CA B1349/P1545  Data-driven approaches to studying disease cell biology: study of neuroblastoma proliferation guided by URSAHD and GIANT functional networks. C.L. Theesfeld1, Y. Lee1,2, C.S. Greene3, A. Krishnan1, A.K. Wong4, E. Riciotti3, R.A. Zelaya3, D.S. Himelstein3, R. Zhang5, S.C. Sealfon6, G.A. FitzGerald3, K. Dolinski1, T. Grosser3, O.G. Troyanskaya1,2,4; 1Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, 2Department of Computer Science, Princeton University, Princeton, NJ, 3Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, 4Simons Foundation, New York, NY, 5Department of Molecular Biology, Princeton University, Princeton, NJ, 6Icahn School of Medicine, Mount Sinai, New York, NY

Embryogenesis 1 B1351/P1546  Decoding Embryonic Developmental Pathways Using 4D-High Content Imaging of C. elegans embryos. R. Khaliullin1,2, S.D. Ochoa1,2, Z. Zhao1,2, S. Wang1,2, R. Biggs1,2, A. Gerson1,2, L. Galanti3, K. Gunsalus3, A.B. Desai1,2, K. Oegema1,2, R.A. Green1,2; 1Cellular and Molecular Medicine, University of California, San Diego, San Diego, CA, 2Ludwig Institute for Cancer Research, San Diego, CA, 3 New York University, New York, NY B1352/P1547  3D visualization of developmental toxicity of 2,4,6-trinitrotoluene in zebrafish embryogenesis using lightsheet microscopy. B.J. Hwang1, J. Eum2, Y. Kee2; 1Dept. of Molecular Bioscience, Kangwon National University, Chuncheon, Korea, 2Division of Biomedical Convergence, Kangwon National University, Chuncheon, Korea B1353/P1548  The role of division orientation in embryonic patterning. L.I. Rathbun1, J. Amack1, H. Hehnly1; 1Cell and Developmental Biology, State University of New York Upstate Medical University, Syracuse, NY B1354/P1549  Imaging How Cells Choose their Fate, Shape and Position in the Early Mouse Embryo. N. Plachta1; 1Institute of Molecular and cell Biology, A*STAR, Singapore, Singapore

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Monday Poster Session B1355/P1550  Alternating muscle contractions establish planar polarity during C. elegans morphogenesis. X. Yang1,2, T. Ferraro1, J. Pontabry2, N. Maghelli3, L. Royer3, S.W. Grill3, G. Myers3, M. Labouesse1,2; 1Developmental biology laboratory, Institut Biologie Paris-Seine, Paris, France, 2Development and stem cells, Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France, 3Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B1356/P1551  Rif1 controls the development of late replication at the Drosophila Mid-Blastula Transition. C.A. Seller1, P.H. O’Farrell1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B1357/P1552  Quantification of centromeric protein dynamics during early embryogenesis of C. elegans. L. Smith1, C.A. Barnhardt2, P.S. Maddox2; 1Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, 2Department of Biology, University of North Carolina, Chapel Hill, NC B1358/P1553  Cellular and Molecular Dynamics Of In-vitro 2D and 3D Cultured Blastocysts Throughout The Implantation Process. S. Karahuseyinoglu1, D. Yucel2, G.N. Sahin3, A. Kocabay4, A.C. Taskin4; 1Histology and Embryology, Koç University School Of Medicine, Istanbul, Turkey, 2Histology and Embryology, Acıbadem University School Of Medicine, Istanbul, Turkey, 3Reproductive Biology, Koç University Graduate School Of Health Sciences, Istanbul, Turkey, 4Animal Research Facility, Koç University College of Sciences, Istanbul, Turkey B1359/P1554  A protein complex directs assembly of the vitelline layer of the C. elegans eggshell. H. Lamb1, D. Partida1, Z. Wilson1, S.K. Olson1; 1Biology, Pomona College, Claremont, CA B1360/P1555  The spatiotemporal limits of developmental Erk signaling. H.E. Johnson1, Y. Goyal2, N. Pannucci1, G.M. Schupbach1, S.Y. Shvartsman2, J.E. Toettcher1; 1Molecular Biology, Princeton University, Princeton, NJ, 2 Chemical Engineering, Princeton University, Princeton, NJ B1361/P1556  Functional roles of hnRNPA2/B1 by RNA epigenetic modification in mammalian embryonic development. J. Kwon1; 1Animal science, Chungbuk national university, Cheongju, Korea, South B1362/P1557  Do amyloid-like complexes control development? An examination of amyloids in Xenopus oocytes and early embryos. M. Hayes1,2, S. Skuodas3, J.S. Fassler3, D.L. Weeks1,2; 1Biochemistry, University of Iowa, Iowa City, IA, 2Molecular and Cellular Biology, University of Iowa, Iowa City, IA, 3Biology, University of Iowa, Iowa City, IA B1363/P1558  A model for how multiprotein regulatory complexes regulate morphogenesis: Abelson tyrosine kinase, Crk, and embryonic development. A.J. Spracklen1, A.N. Bonner2, E.M. Rogers2, M. Peifer1,2; 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC

B1364/P1559  Expression and functional analysis of Smyd5 in zebrafish. T. Fujii1, H. Sagara2, M. Munakata1, Y. Hisaki1, T. Sekiya1, Y. Furukawa3, K. Sakamoto4, S. Watanabe5; 1Department of Cancer Genome Research, Sasaki Institute, Sasaki Foundation,, Tokyo, Japan, 2Fine Morphological Analysis Group Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 3Division of Clinical Genome Research, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 4Department of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan, 5Division of Molecular and Developmental Biology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan B1365/P1560  ADAM 13 cleaves PCNS and regulates its expression via AP2a to promote cranial neural crest cell migration. V. Khedgikar1, K. Mathavan1, H. Cousin1, D. Alfandari1; 1Dept. of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA B1366/P1561  Role of antiapoptotic genes in developmental biology: A tale of TMBIM family proteins in Zebra fish. R. JUNJAPPA1, M. Handigund1, K.R. Bhattarai1, H.K. Kim1, H.R. Kim 1, H.J. Chae1; 1Department of Pharmacology, School of Medical Science, Chonbuk National University, Jeonju, Jeollabuk-do, Korea B1367/P1562  A Molecular Genetic Analysis of the Role of Carbonic Anhydrases in Tracheal Filling of Drosophila melanogaster. G.H. Jean1, M. Keroles1, S. McGriff1, J. Nair1, C. Kowalczyc1, B. Russel1, J. Arvedon1, J. Baker1; 1Biology, University of Miami, Coral Gables, FL B1368/P1563  xDACH1 regulates neural development via regulating transcription of tissue specific genes. K. Yookyung1, T. Ismail1, G. Park1, H. Lee1; 1Biotechnology, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, DAEGU, Korea, South B1369/P1564  Histone demethylase Kdm3a/ Jmjd1a regulates craniofacial and neural development. H. Lee1, Y. Jeong1, C. Kim1, H. Lee1; 1Biotechnology, Kyungpook National University, Daegu, Korea, South B1370/P1565  Safe dose of bisphenol A to mothers during gestation and lactation increases proliferative rate and neoplastic lesions in mammary gland of female gerbil (Meriones unguiculatus) offspring. E.R. Leonel1, S.P. Campos1, D. Leonel1, L. FalleirosJunior1, S. Taboga1; 1Departament of Biology, São Paulo State University (IBILCE/UNESP), São José do Rio Preto, Brazil

Signaling in Tissue Development and Morphogenesis B1400/P1566  B cell Specific Knockout of Gps2 leads to defective B cell development and aberrant BCR/TLR activation. C. Lentucci1, A. Belkina1, C.T. Cederquist1, M. Chan1, H.E. Johnson1, S. Prasad1, A. Lopacinski1, b. Nikolajczyk1, S. Monti1, J. Snyder-Cappione1, B. Tanasa2, M.D. Cardamone1, V. Perissi1; 1Biochemistry, Boston University, Boston, MA, 2 Pediatrics, Stanford University, Stanford, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1401/P1567  Neprilysin facilitates adipogenesis through potentiation of the PI3K signaling pathway. J. Kim1, D. Han1, S. Byun1, M. Kwon1, K. Yoon1; 1Genetic Engineering, Sungkyunkwan Univ, Suwon, Korea, South B1402/P1568  Regenerative activation of wingless regulates loss of cell polarity and neoplastic transformation in lgl mutant epithelia. R. Jaszczak1, R. Bhandari1, T. Tran1, A. Halme1; 1Cell Biology, University of Virginia School of Medicine, Charlottesville, VA B1403/P1569  Endocytosis of Wingless via a dynamin-independent pathway is necessary for signalling in Drosophila wing discs. A. Hemalatha1, C. Prabhakara1, S. Mayor1; 1Cellular Organization and Signaling, National Centre for Biological Sciences, Bangalore, India B1404/P1570  Roles for Wnt signaling in synapse organization revealed by CRISPR/ Cas9-mediated mutagenesis in the mouse retina. S. Sarin1, E. Zuniga-Sanchez2, M.B. Patel1, K. Zhang2, H. Cousins1, J.R. Sanes1, S. Zipursky2; 1Molecular and Cellular Biology, Harvard University, Cambridge, MA, 2Biological Chemistry, University of California, Los Angeles, Los Angeles, CA

B1406/P1572  SFI1 recruits USP9X to stabilize the microcephaly protein STIL. A.T. Kodani1,2, J.F. Reiter2, C.A. Walsh1; 1Genetics and Genomics, Boston Children’s Hospital, Boston, MA, 2Biochemistry and Biophysics, UCSF, San Francisco, CA B1407/P1573  ASP suppresses microcephaly through spindle-independent pathways. T.A. Schoborg1, L. Smith1, C.J. Fagerstrom1, N.M. Rusan1; 1National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD B1408/P1574  Spatially patterned EGF receptor signaling controls cell mechanics and square cell packing. M. Tamada1, J. Zallen1; 1Developmental Biology Program, Sloan Kettering Institute, New York, NY B1409/P1575  Fine tuning of G-Protein Coupled Receptors (GPCRs) signaling during epithelial morphogenesis. A. Jha1, S. Kerridge1, J. Phillippe1, T. Lecuit1; 1Development biology, Institut de Biologie du Développement de Marseille, Marseille, France B1410/P1576  A tough egg to crack: how does BMP signaling regulate epithelial morphogenesis in the Drosophila ovary? J.C. Duhart1, J. Guerrero1, T.T. Parsons1, L.A. Raftery1; 1School of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV B1411/P1577  Klf2 is required for myocardial wall integrity in zebrafish. S.J. Rasouli1, D. Stainier1; 1Dept.III- Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

B1412/P1578  Genetic Variants in NPPA are Associated with Ventricular Septal Defects. Y. Feng1, X. Ma1, Y. Yang1, J. Zhu1, Q. Wu2, X. Mo3, R.S. Adelstein1; 1Laboratory of Molecular Cardiology, NHLBI/NIH, Bethesda, MD, 2Molecular Cardiology, Cleveland Clinic, Cleveland, OH, 3Department of Cardiothoracic Surgery, Children’s Hospital of Nanjing Medical University, Nanjing, China B1413/P1579  Macrolactin F inhibits RANKLmediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP-2/smad/Akt/Runx2 signaling pathway. Y. Soh1, L. Li1, M. Sapkota1; 1Department of Dental Pharmacology, School of Dentistry, Chonbuk National University, Jeonju, Korea, South B1414/P1580  Role of Shh signaling in mouse sacral intervertebral disc. R. Bonavita1, R. Pinelli1, E. De Jesus1, C.L. Dahia1,2; 1Hospital for Special Surgery, New York, NY, 2Weill Cornell Medical College, New York, NY B1415/P1581  TGF-b Signaling Regulates Cementum Formation via Osterix during Tooth Development. H. Choi1, Y. Ahn1, T. Kim 1, C. Bae1, J. Lee 1, H. You2, E. Cho1; 1Dental school, Chonbuk National University, Jeonju, Dem People, 2School of Dentistry, Wonkwang University, Iksan, Dem People B1416/P1582  Proteomic Characterization of Epicardial-Myocardial Signaling Reveals Novel Regulatory Networks Including a Role for NF-κB in Epicardial EMT. Y. Li1, A. Urban2, D. Midura2, H. Simon2, Q. Wang1; 1Department of Biological Sciences, University of Illinois at Chicago, CHICAGO, IL, 2Department of Pediatrics, Northwestern University, Chicago, IL B1417/P1583  The E3 ubiquitin ligase, Fbxw7, regulates many aspects of Schwann cell development and myelination by controlling mTOR levels. B.L. Harty1, S.D. Ackerman1, J.P. Golden2,3, M. Stephen4, M. MacEwan4, A.L. Herbert1, C.L. Johnson1, R.W. Gereau2,3, K.R. Monk1,5; 1Developmental Biology, Washington University School of Medicine, St Louis, MO, 2 Anesthesiology, Washington University School of Medicine, St Louis, MO, 3Washington University Pain Center, St Louis, MO, 4Neurosurgery, Washington University School of Medicine, St Louis, MO, 5Hope Center for Neurological Disorders, St Louis, MO B1418/P1584  MARVELD1 Regulates Cerebellar Development by Controlling Neuron Migration. W. Liu1, S. Qu1, C. Wang1, F. Han1, H. Sun1, Y. Li1; 1school of life science and technology, Harbin Institute of Technology, Harbin, China B1419/P1585  Unidirectional Eph/Ephrin signaling drives cell segregation by the generation of a cortical actin differential. J.O. Bush1, A.K. ONeill1, T.K. Niethamer1, A.A. Kindberg1; 1Department of Cell and Tissue Biology and Program in Craniofacial Biology, University of California at San Francisco, San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1420/P1586  Characterization of the spatiotemporal localization of the growth factor Neuregulin-3 in the central nervous system. A. Rahman1, J.L. Weber2, C. Lai1, A.L. Prieto1; 1Psychological and Brain Sciences, Indiana University, Bloomington, IN, 2Neuroscience, University of California San Diego, San Diego, CA B1421/P1587  Contributions of TGF-beta Signaling in Insulin-induced Angiogenic Response. E.H. Budi1, R. Derynck1; 1Department Cell and Tissue Biology, University of California at San Francisco, San Francisco, CA B1422/P1588  The effects of low-level copper exposure on axonal pathfinding in the embryonic zebrafish. J. Pagnotta1, K. Figueroa1, I. Mazaharul1, A.L. Dell1,2; 1Biology, St. Francis College, Brooklyn, NY, 2Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA B1423/P1589  MicroRNA­-430 is important for proper endodermal and cardiac cell migration during early zebrafish heart development. M. Sandoval1, A.A. Kuwahara1, C. Doganli1, D. Hart1; 1CVRI, University of California, San Francisco, San Francisco, CA B1424/P1590  Involvement of phospholipase C-related but catalytically inactive protein in the early stage of osteoclast differentiation. M. Matsuda1, A. Murakami1, M. Hirata1; 1Faculty of Dental Science, Kyushu University, Fukuoka, Japan B1425/P1591  Coordination of neural patterning and morphogenesis in the frog by repression of oct4 family pluripotency factors. C. Exner1, R.M. Harland1; 1Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA B1426/P1592  Ultrastructural evidence that basally located cells in the epididymal epithelium constitute distinct cell types with unique gene regulators. L. Hermo1, R. Oliveira1, J. Dufresne2, M. Gregory2, D.G. Cyr1,2; 1Anatomy and Cell Biology, McGill University, Montreal, QC, 2Toxicology and Pharmacology, INRSInstitut Armand-Frappier, Laval, QC B1427/P1593  Nicotine activation of an epidermal wound response during Drosophila puncture injury. M.T. Juarez1; 1Sophie Davis Program in Biomedical Education, City College New York, New York, NY

Cell Biology of Protists and Viruses B1429/P1594  Regulation of Plasmodium falciparum origin recognition complex subunit 1 (ORC1) function through phosphorylation mediated by CDK-like kinase PK5. M. Agarwal1, A.S. Deshmukh1, S.K. Dhar1; 1Special center for molecular medicine, Jawaharlal Nehru university, New Delhi, India B1430/P1595  Discovery of an Anti-Malarial Inhibitor with a Novel Mechanism of Action Targeting Secondary Plastid Biogenesis. K. Amberg-Johnson1, K. Hong2, E. Yeh1,2; 1Microbiology and Immunology, Stanford University, Stanford, CA, 2Biochemistry, Stanford University, Stanford, CA

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B1405/P1571  Role of Notch signaling during ommatidial rotation in Drosophila eye. Y. Koca1, M. Mlodzik1; 1Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY

Monday Poster Session

Board No./Presentation No. B1431/P1596  Preliminary Data on Interactions Between Carnivorous Amoeba proteus and Pathogenic Listeria monocytogenes. Y. Podlipaeva1, V. Pushkareva2, S. Ermolaeva2, A. Goodkov1; 1Institute of Cytology, Saint Petersburg, Russia, 2Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia B1432/P1597  The role of the vacuolar ATPase in alphavirus replication. R. Schuchman1, R. Vancini1, A. Piper1, D. Breuer1, M. Ribeiro1, D. Farreira1, J. Magliocca1, V. Emmerich1, R. Hernandez1, D. Brown1; 1Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC B1433/P1598  Control of acidocalcisome phosphate transport by 5-diphosphoinositol pentakisphosphate (IP7) in Trypanosoma brucei. C. Cordeiro1,2, E. Potapenko1, G. Huang1, H.J. Jessen3, A. Saiardi4, R. Docampo1,2; 1Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, 2Department of Cellular Biology, University of Georgia, Athens, GA, 3Department of Chemistry and Pharmacy, University of Zürich, Zurich, Switzerland, 4Department of Cell and Developmental Biology, University College London, London, United Kingdom B1434/P1599  Septins suppress the release of vaccinia virus from infected cells. J. Pfanzelter1, M. Way1, S. Mostowy2; 1Cellular signalling and cytoskeletal function, The Francis Crick Institute, London, United Kingdom, 2MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom B1435/P1600  Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. A. Ludwig1, T.H. Nguyen1, S. Sandin1, R.J. Sugrue1; 1School of Biological Sciences, Nanyang Technological University, Singapore, Singapore B1436/P1601  Multi-purpose use of endoplasmic reticulum membranes by coronaviruses as revealed by large volume electron tomography. E.M. Mihelc1, S.C. Baker2, J.K. Lanman1; 1Biological Sciences, Purdue University, West Lafayette, IN, 2Microbiology Immunology, Loyola University Chicago Stritch School of Medicine, Maywood, IL B1437/P1602  Roles for HIV-1 Matrix, Rho Family GTPases, and Extracellular Viscosity in Regulating Envelope-Induced Cell-Cell Fusion. N.M. Sherer1, J.C. Gardiner1; 1McArdle Laboratory for Cancer Research and Institute for Molecular Virology, University of WisconsinMadison, Madison, WI B1438/P1603  Histone-deacetylase 6 links autophagy induction with reactivation of Kaposi’s Sarcoma Associated Herpesvirus from latency. H. Mello1, H. Shin1, D. Palmeri1, D. Lukac1; 1Department of Microbiology, Biochemistry and Molecular Genetics, Graduate School of Biomedical Sciences, Rutgers University, Newark, NJ

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Monday Poster Session B1439/P1604  Post-translational modifications of the Human Papillomavirus type 16 Major capsid protein that mediate virion assembly and viral infectivity. D.C. Pim1, P. Massimi1, J. Broniarczyk1,2, M.P. Myers3, R.L. Garcea4, L. Banks1; 1Dept. of Tumour Virology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy, 2Dept. of Molecular Virology, Adam Mickiewicz University, Poznan, Poland, 3Dept. of Protein Networks, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy, 4The BioFrontiers Institute, University of Colorado, Boulder, CO B1440/P1605  Characterising the spatiotemporal role of cargo protein sorting nexin 17 in human papillomavirus trafficking. M. Bergant1, S. Peternel1, D.C. Pim2, J. Broniarczyk2,3, L. Banks2; 1Centre for Biomedical Sciences and Engineering, University of Nova Gorica, Nova Gorica, Slovenia, 2Tumour Virology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy, 3Department of Molecular Virology, Adam Mickiewicz University, Poznan, Poland B1441/P1606  A Screen of Host-Targeting Compounds identifies Potential Inhibitors of Zika Virus Infection. R. Khachatoorian1, V. Arumugaswami2, S.W. French1; 1Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, 2Surgery, Cedars-Sinai Medical Center, Los Angeles, CA B1442/P1607  Temporal Variation in the Prevalence of Human Intestinal Parasite in Two Bivalve Species Collected from Orchard Beach, NY. F.F. Tei1, S. Kowalyk1, M. Presta1, J. Reid1, C. Annabi1, M. Fazeem1, J. Annabi1, G. Mayer1; 1Biology, Manhattan College, Riverdale, NY B1443/P1608  Temporal and Spatial Variation in the Prevalence of Human Intestinal Parasites in Domestic Dogs from the Eastern United States. J. Munoz1, E. Bailey1, D. Frederick2, T. Porter2, C. Woods2, P. Jackson-Miller2, J. Riley2, A. Kennedy1, S.O. Kwabena2, C. Hines2, J.M. Porter-Kelley2, G. Mayer1; 1Biology, Manhattan College, Riverdale, NY, 2Biological Sciences, Winston Salem State University, Winston Salem, NC B1444/P1609  Genetic and Small-molecule Approaches Establish Casein Kinase 1.2 as a Regulator of Basal Body Biogenesis in the African Trypanosome. C. Sullenberger1, J. Wiedeman1, K.A. Mensa-Wilmot1; 1Cellular Biology, University of Georgia, Athens, GA B1445/P1610  Identification of a unique Plasmodium protein and its possible role in modifying the host erythrocyte. G.T. Cortés1, M.F. Wiser2, C.J. Gómez3; 1Departamento de Salud Pública, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C., Colombia, 2Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 3Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, Bogotá, D.C., Colombia B1446/P1611  The Lifecycle of a Haemohormidium-like Parasite infecting Caribbean Stegastes damselfishes. J.B. Robinson1, A.K. Halliday1, S.M. Liburd1, P.C. Sikkel2, A.G. Campbell3; 1College of Science and Math, University of the Virgin Islands, St. Thomas, VI, 2Department of Biology, Arkansas State University, Jonesboro, AR, 3Bio Med Molecular, Microbiology Immunology, Brown University, Providence, RI

B1447/P1612  Characterization of the Microbiome of a Geothermal Pool Proximal Species Pisolithus tinctorius. C. Cole1, I. Rubio1, H. Warbington1, M. Kaze1; 1Biological Sciences, California State University East Bay, Hayward, CA B1448/P1613  Uncovering the path of death: following the evolution of erythrocyte invasion. J. Toscani Field1, J. Weinberg1, R. Sehgal1; 1Biology, San Francisco State University, San Francisco, CA B1449/P1614  Variations in Arsenite Resistance of the Gliding Euglena. D.G. Cole1, N.L. Rosendo Mercado1,2; 1Biological Sciences, University of Idaho, Moscow, ID, 2Science and Technology, Inter American University of Puerto Rico, Barranquitas, PR B1450/P1615  RNA-sequencing in diatoms: identifying genes and mechanisms related to cell wall morphology. J.J. Russell1, J.A. Theriot2; 1Biology, Stanford University, Stanford, CA, 2Biochemistry, Stanford University, Stanford, CA

Host-Pathogen/HostCommensal Interactions 1 B1451/P1616  The usefulness of enteroidsderived monolayers in the study of enteric infections. E. Lim1, K. Suarez1, R. Jayaratne2, Y. Chuang1, K. Barrett2, S. Das1; 1Pathology, University of California, San Diego, San Diego, CA, 2Medicine, University of California, San Diego, La Jolla, CA B1452/P1617  Genome-wide landscape of phage secondary integration sites and their phenotypic effects on host physiology. Y. Tanouchi1, M.W. Covert1; 1Bioengineering, Stanford University, Stanford, CA B1453/P1618  Characterization of Peptide Binding by a Protective Ebola Antibody. E.C. Gierman1,2, D. Martinez-Guzman1, J. Berry1, E.A. Booth1; 1Immunochemistry Research, Grifols Diagnostic Solutions, Emeryville, CA, 2 School of Public Health, University of California, Berkeley, Berkeley, CA B1454/P1619  Studying E-Cadherin’s Role in Facilitating L. monocytogenes CellCell Spread Between Adjacent Epithelial Cells. P. Radhakrishnan1, J.A. Theriot1, F.E. Ortega1; 1Biochemisty, Stanford University, Stanford, CA B1455/P1620  Early activation of STAT1 induced by influenza virus is independent of cytokines and Jak kinases and critically required for initial antiviral immunity. S. Liu1, J. Hu1, J. Chen2, Z. Yu2; 1Institute of Microbiology, Chinese Academy of Sciences, Beijing, China, 2College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, China B1456/P1621  Electrophysiological properties of macrophage-like cell line J774A.1 during the internalization of outer membrane vesicles (OMV) from Escherichia coli JC8031. A.F. Leal1,2, M.M. Camacho1, J.D. Valderrama2, M.E. Forero2; 1Universidad Nacional de Colombia, Bogota, Colombia, 2Universidad Antonio Nariño, Bogotá, Colombia

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1457/P1622  Characterization of Adenovirus SUMO E3 Ligase E4-ORF3: A Viral Polymer Protein Enhances SUMO Polymerization. S. Sohn1, P. Hearing1; 1Molecular Genetics and Microbiology, School of Medicine, Stony Brook University, Stony Brook, NY B1458/P1623  Field detection of Borrelia burgdorferi, Anaplasma phagocytophilium and Babesia microti in Ixodes scapularis samples. A.J. Prunuske1, C. Fisher2, N. Lipiniski2, J. van Westrienen3; 1Microbiology and Molecular Genetics, Medical College of Wisconsin, Wausau, WI, 2Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN, 3 Biomeme, Philadelphia, PA B1459/P1624  The role of sterol transfer in coral-algal symbiosis. E.A. Hambleton1, N. Bechtoldt1, A. Guse1; 1Centre for Organismal Studies, Heidelberg University, Heidelberg, Germany

B1461/P1626  Association of Tobacco mosaic virus (TMV) 126 kDa protein with prevacuolar/tonoplast syntaxins. A. Ibrahim1, K. Cooper1, X. Yang1, J. Schoelz2, R. Nelson1; 1Plant Biology Division, The Samuel Roberts Noble Foundation, Ardmore, OK, 2Division of Plant Sciences, University of Missouri, Columbia, MO B1462/P1627  Infection of Pseudomonas aeruginosa selectively affects human leukocyte antigen (HLA) gene expression. A. Caobi1, S. Mustafi2, S. Singh1, M. Veisaga1, M.T. Dorak3, M.A. Barbieri1; 1Biology, Florida International University, Miami, FL, 2John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, 3Health Sciences, Liverpool Hope University, Liverpool, United Kingdom B1463/P1628  Microbiota diversity on healthy women’s face in relation to skin biophysical characteristics. C. Heusèle1, V. JeronimoMonteiro1, S. Quéniot1, B. Beaufrère-Seron1, S. Schnebert1, M. Dumas1, E.K. Kim2, W.J. Lee2; 1Life Sciences, LVMH Recherche, Saint Jean de Braye, France, 2School of Biological Sciences, Seoul National University, Seoul, Korea B1464/P1629  A quantitative analysis of single-cell TLR signaling dynamics in response to Salmonella infection. K. Lane1, M. Andres Terre2, T. Kudo1, D. Monack2, M.W. Covert1; 1Bioengineering, Stanford University, Stanford, CA, 2Microbiology and Immunology, Stanford University, Stanford, CA B1465/P1630  A new zebrafish model for the study of biofilm formation and eradication. P. Rodriguez1, L.R. Vega1, B. Schoffstall1; 1Biology, Barry University, Miami, FL B1466/P1631  Adrenergic Receptor Antagonists Mediate Differential Transcriptomic Responses During Neuroendocrine Crosstalk with the Skin Microbiome that Ameliorate Bacterial Growth and Biofilm Formation. J.J. Fuentes1, S. Singh1, R.R. Isseroff 2, R.W. Crawford1; 1Biological Sciences, California State University, Sacramento, Sacramento, CA, 2 Dermatology, University of California, Davis, Davis, CA

B1467/P1632  Understanding the roles of vacuolar - ATPase proton pumps in the pathogenic fungus Candida albicans. M.M. Grimes1, S.R. Hayek1, H. Rane2, S.A. Lee 2,3, K.J. Parra1; 1Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM, 2Division of Infectious Disease, New Mexico Veterans Healthcare System, Albuquerque, NM, 3Division of Infectious Disease, University of New Mexico, Albuquerque, NM B1468/P1633  Microbiome-Free Fatty Acid Cross-Talk in the Human Pilosebaceous Gland and Consequences for Colonization Resistance. S. Singh1, W. Burney2, J.J. Fuentes1, T.L. Davis1, E.E. Andersen1, N. Foolad2, R. Sivamani2, R.W. Crawford1; 1Department of Biological Sciences, California State University, Sacramento, Sacramento, CA, 2Department of Dermatology, University of California, Davis, Sacramento, CA B1469/P1634  Novel post-integration speciesspecific barriers affecting persistent HIV-1 gene expression in non-human cells. E.L. Evans1, J.T. Becker1, S.L. Fricke1, N.M. Sherer1; 1Oncology and Institute for Molecular Virology, University of Wisconsin-Madison, Madison, WI B1470/P1635  Novel Proteomics Tools to Probe the Roles of ADP-ribosylation in RNA granules and RNA Virus Infection. A.K. Leung1; 1Department of Biochemistry and Molecular Biology, Johns Hopkins University, Baltimore, MD

Cell Signaling in Normal and Diseased Organs B1472/P1636  Deletion of DGK epsilon attenuates lipolytic activity in adipocytes under high fat diet conditions. T. Nakano1, K. Goto1; 1Anatomy and Cell Biology, Yamagata University, Yamagata City, Japan B1473/P1637  Implication of autophagy and ceramide production in lipotoxicity effects on human kidney epithelial cells. G. Li1, M.N. Juma’at1, M.M. Tong1, C.S. Yap1, Y.M. Bee2; 1Department of Clinical and Translational Research, Singapore General Hospital, Singapore, Singapore, 2Department of Endocrinology, Singapore General Hospital, Singapore, Singapore B1474/P1638  KCNMA1 contributes to the regulation of insulin signalling in mature adipocytes. M. Nishizuka1, W. Horinouchi1, E. Yamada1, S. Osada1, M. Imagawa1; 1Department of Molecular Biology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan B1475/P1639  Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. A. Didonna1, E. Cekanaviciute1, J.R. Oksenberg1, S.E. Baranzini1; 1Neurology, University of California San Francisco, San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1476/P1640  Selenoproteins regulate B cell functions by targeting B cell receptormediated antigen presentation pathway. B. Katkere1, R.L. Markley1, D.R. Williamson1, A.E. Shay1, K.S. Prabhu1, G.S. Kirimanjeswara1, B.A. Carlson2; 1Veterinary and Biomedical Sciences, Penn State University, University Park, PA, 2National Cancer Institute, National Institutes of Health, Bethesda, MD B1477/P1641  Tyramine Function within the Mouse Uterus. B. Obayomi1, M. Agre1, D.P. Baluch1; 1School of Life Sciences, Arizona State University, Tempe, AZ B1478/P1642  Regulation of hepcidin expression by IL-1beta-NFkappaB signaling. Y. Kanamori1, M. Murakami2, T. Matsui1, M. Funaba1; 1Graduate School of Agriculture, Kyoto University, Kyoto, Japan, 2School of Veterinary Medicine, Azabu University, Sagamihara, Japan B1479/P1643  The role of the TGF-beta signaling effector SMAD3 in adipogenesis. E. Bielczyk-Maczynska1, M. Teruel1; 1Department of Chemical and Systems Biology, Stanford University, Palo Alto, CA B1480/P1644  Anti-melanogenic potential of Heracleum moellendorffii extract via ERK1/2-mediated MITF degradation. M. Alam1, B. Seo1, P. Zhao1, H. Son1, C. Jeong1, J. Byeon1, H. Kim2, S. Lee1; 1Food Science and Biotechnology, Kyungpook National University, Daegu, Korea, South, 2MR Innovation, Convergence Technology Bldg., Kyungpook National University, Daegu, Korea, South B1481/P1645  Anti-Diabetic effect of Glyceollin, a soybean isoflavone, via a CaMKKAMPK pathway in L6 myotubes. E. Yoon1, C. Yoo1, Y. Kim1, S. Lee1, Y. Kim2, S. Lee1; 1Food Science and Biotechnology, Kyungpook National University, Daegu, Korea, South, 2NB Co., Ltd., Techno Building,, kyungpook National University, Daegu, Korea, South B1482/P1646  Inhibition of melanin biosynthesis by sesamol via the intracellular cAMP and p38/JNK signaling pathways. S. Baek1, M. Alam2, H. Lee2, K. Kwon2, H. An2, S. Lee2; 1Nanobiotech, Bio Venture Center, Daejeon, Korea, South, 2Food Science and Biotechnology, Kyungpook National University, Daegu, Korea, South B1483/P1647  Ca2+/Calmodulin-mediated Tie2 suppression acts as a developmental brake during embryonic angiogenesis. C. Yang1,2, E. Kim2, J. Kim2, D. Park1, C. Kim2; 1School of Biological Sciences, Seoul National University, Seoul, Korea, South, 2Department of Life Sciences, Korea University, Seoul, Korea, South B1484/P1648  Systemic pharmacological HIF stabilization protects retinal vasculature from oxygen toxicity and prevents ischemic retinopathy. G. Hoppe1, S. Yoon1, E.R. Chan2, J.E. Sears1; 1Cole Eye Institute, Cleveland Clinic, Cleveland, OH, 2Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OH

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B1460/P1625  Protective activities of oligomer of GlcNAc against mycelial growth of Candida albicans in vitro and in vivo. S.A. Ishijima1, T. Fukamizo2, K. Satoh3, T. Noguchi3, Y. Guo1, T. Yamada1, S. Abe1; 1Institute of Medical Mycology, Teikyo University, Tokyo, Japan, 2 Department of Advanced Bioscience, Kindai University Faculty of Agriculture, Nara, Japan, 3 Koyo Chemical Co., LTD., Osaka, Japan

Monday Poster Session

Board No./Presentation No.

Monday Poster Session

B1485/P1649  Polyphenolic compounds protect platelet cells during storage through reducing activation, apoptosis and sialidases activity. M. Handigund1, Y.G. Cho1,2, J. Lee1; 1Department of Laboratory Medicine, Chonbuk National University Medical School, Jeonju, AK, 2Biomedical Research Institute of Chonbuk National University, Research Institute of Clinical Medicine of Chonbuk National University, Jeonju, AR

Digestive and Excretory Organs B1486/P1650  Investigation of the role(s) of a macromolecular complex of CFTR-NHERF2LPA2 in the fluid hemostasis and inflammatory responses in intestinal epithelial cells. S. Kong1; 1Pediatrics, University of Tennessee Health Science Center, Memphis, TN B1487/P1651  Fibrosis and cholangiocyte damage are decreased in l-histidine decarboxylase knockout mice (HDC-/-) fed a chronic high-fat diet via dysregulated leptin signaling. L. Kennedy1,2, L. Hargrove3, J. Demieville2, F. Meng1,2,3, H.L. Francis1,2,3; 1Internal Medicine, Texas AM HSC COM, Temple, TX, 2Research, Central Texas Veterans Health Care System, Temple, TX, 3Academic Operations, Baylor Scott White Health, Temple, TX B1488/P1652  Gastric 17β-estradiol synthesis and secretion in rats. H. Kobayashi1, S. Yoshida1, Y. Sun1, N. Shirasawa2, A. Naito1; 1Anatomy and Structural Science, Yamagata university, Yamagata, Japan, 2Rehabilitation, Tohoku Bunka Gakuen University, Sendai, Japan B1489/P1653  Simulating acetaminophen pharmacology and idiosyncratic responses using a virtual human liver. X. Fu1,2, J.P. Sluka1,3, M. Swat1, J.M. Belmonte1,2, S.G. Clendenon1,3, J.F. Wambaugh4, J.A. Glazier1,2,3; 1Biocomplexity Institute, Indiana University Bloomington, Bloomington, IN, 2 Department of Physics, Indiana University Bloomington, Bloomington, IN, 3Department of Intelligent Systems Engineering, Indiana University Bloomington, Bloomington, IN, 4National Center for Computational Toxicology, US EPA, Research Triangle Park, NC B1490/P1654  Analysis of early biomarkers of acute kidney injury in Chinese kidney transplant patients. Y. Huang1, L. Shuai1, J. Zhang 1 , W. Shang2, A. Qiu1; 1School of Life Sciences and Technology, Tongji University, Shanghai, China, 2The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China B1491/P1655  Coagulation factor IX improves the prognosis of pulmonary edema under the hypoxia. Y. Fujiwara1, H. Kitano2, A. Mamiya2, C. Hidai1, K. Shinichiro1; 1Biomedical Sciences, Nohon University School of Medicine, Tokyo, Japan, 2Division of Dental Surgery, Nihon University School of Medicine, Tokyo, Japan B1492/P1656  Exosomes produced by normal hepatocytes reverse experimental liver fibrosis and hepatocyte injury. L. Chen1, R. Chen1, S. Kemper1, D.R. Brigstock1,2; 1Clinical and Translational Research, Nationwide Childrens Hospital, Columbus, OH, 2Surgery, The Ohio State University, Columbus, OH

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Tuesday Poster Session ASCB Learning Center, Exhibit Halls A-C Poster Set Up Monday 6:00–6:30 pm Posters Displayed Monday 6:30–8:00 pm Tuesday 7:30 am–3:00 pm

Author Presentation Odd Boards 12:00–1:30 pm Even Boards 1:30–3:00 pm Poster Tear Down Tuesday 3:00–4:00 pm*

*TUESDAY PRESENTERS: REMOVE ALL POSTERS BY 4:00 PM OR THEY WILL BE DISCARDED. THERE WILL BE ABSOLUTELY NO ACCESS TO THE ASCB LEARNING CENTER AFTER 4:00 PM. NO EXCEPTIONS!

Board Numbers Session Titles S ingle Molecule and Super-Resolution in New Imaging Technologies New Techniques in Proteomics New Techniques in Mechanobiology Actin and Actin-Associated Proteins 3 Regulation of Actin Dynamics 2 Kinesins 2 Dynein Tubulin and Associated Proteins Microtubule Dynamics and Its Regulation 2 Ciliary Formation and Trafficking Cytokinesis 2 Chromosome Organization in Meiosis Spindle Assembly 3 Kinetochore Assembly and Functions 3 Cancer Therapy 3 Cancer Stem Cells Oncogenes and Tumor Suppressors 3 Regulators of Invasion and Metastasis Chromatin and Chromosome Organization Epigenetics and Chromatin Remodeling Nuclear Lamina and Laminopathies Nucleocytoplasmic Transport Vesicle Docking and Fusion Endosomes, Lysosomes, and Lysosome- Related Organelles 2 Membrane Fission and Coat Proteins Polarity in the Development of Tissues and Organisms

B1035-B1050 B1052-B1065 B1066-B1087 B1100-B1109 B1110-B1125 B1126-B1140 B1141-B1165 B1200-B1211 B1212-B1226 B1228-B1245 B1246-B1261 B1263-B1273 B1274-B1289; B1300-B1306 B1308-B1316 B1318-B1330 B1331-B1344 B1345-B1356 B1357-B1371; B1400-B1409 B1411-B1429 B1431-B1450 B1451-B1465 B1466-B1487

T he Synapse Establishing and Maintaining Organelle Structure 2 Mitochondria, Chloroplasts, and Peroxisomes 3 Rho-Family GTPases Kinases and Phosphatases 2 Signaling Receptors (RTKs and GPCRs) 2 Mechanotransduction 2 Dynamics of Focal Adhesions and Invadosomes Chemotaxis and Directed Cell Migration Cell-Cell Junctions 2 Bioengineering of Cell-Matrix Interactions Regulation of Aging Autophagy Chemical Approaches to Cell Biology Embryogenesis 2 Cytoskeleton in Tissue Development and Morphogenesis Cell Fate Determination 2 Stem Cells and Pluripotency Host-Pathogen/Host-Commensal Interactions 2 Immune System Defining Therapeutic Targets and New Therapeutics 2 Muscle Structure, Function, and Disease

2016 Meeting Poster Presentation Guidelines •

Presenters should ensure their posters are placed on the appropriate poster board for the duration of their assigned poster session and viewing. Please use the number starting with “B” for your poster board.



Poster presenters should stand at their poster locations during the appropriate 90-minute time slot—odd board numbers, 12:00-1:30 pm or even board numbers, 1:30-3:00 pm (specific time slot is included in the original poster notification emails sent on November 2). If presenters have to leave early, they should post a note on their boards with contact information or stating when they will be available to answer attendee questions.



IMPORTANT! Poster presenters are solely responsible for placing and removing their poster according to the schedule provided above. If you are unable to set up your poster the evening before your session, please do so the morning of your presentation.



Tuesday presenters must take down their posters between 3:00 pm and 4:00 pm. Posters that are not removed from their boards at the designated time or that are left in the Exhibit/Poster Hall will be discarded. No Exceptions!



Poster presenters should not leave any items unattended at their poster board, including poster tubes, meeting bags, Programs, Poster Guides, personal items, etc. The ASCB is not responsible for any items left in the ASCB Learning Center.



Cameras/Photography: Cameras and all other recording devices are strictly prohibited in all session rooms, in the ASCB Learning Center, and in all poster and oral presentation sessions.

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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B200-B217 B218-B231 B232-B246 B248-B271 B272-B293 B295-B299; B300-B309 B310-B326 B328-B344 B345-B360 B361-B389 B401-B426 B427-B435 B436-B454 B455-B472 B474-B489; B500-B514 B515-B525 B526-B538 B539-B554 B556-B571; B900-B904 B905-B916 B918-B927 B928-B950 B952-B970 B971-B987 B1000-B1009 B1011-B1033

Board No./Presentation No.

Single Molecule and Super-Resolution in New Imaging Technologies B200/P1657 Resolving the molecular architecture of the NPC with 3D superresolution fluorescence microscopy. V. Jimenez-Sabinina1, M. Bates2, A.B. Szymborska3, B. Nijmeijer1, S. Mosalaganti4, M. Beck4, S.W. Hell2, J. Ellenberg1; 1Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany, 2NanoBiophotonics Department, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 3Max Delbrück Center for Molecular Medicine, Berlin, Germany, 4Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany B201/P1658 Fast TCSPC Based Superresolution Microscopy Optimized for Hz Image Frame Rates with High Photon Throughput. B. Kraemer1, P. Reisch1, M. Sackrow1, S. Orthaus-Mueller1, S. Tannert1, O. Schulz1, F. Koberling1, P. Tan2, E. Lemke2, R. Erdmann1; 1PicoQuant GmbH, Berlin, Germany, 2Cell Biology and Biophysics Unit, EMBL, Heidelberg, Germany B202/P1659 Spectrally resolved superresolution fluorescence microscopy. K. Xu1; 1Department of Chemistry, University of California, Berkeley, Berkeley, CA B203/P1660 3D Imaging of Whole Unstained Cells at Super-resolution – a laboratory scale cryo soft X-ray tomography microscope. F. O Reilly1,2, K. Fahy2, T. McEnroe2, J. Howard2, R. Byrne2, A. Mahon2, O. Hammad2, P. Dunne1, G. O Sullivan1, E. Sokell1, P. Sheridan2; 1School of Physics, University College Dublin, Dublin, Republic of Ireland, 2SiriusXT, Dublin, Republic of Ireland B204/P1661 Defining caveolae and scaffolds by computational network analysis of particle localization superresolution microscopy. I. Khater1, F. Meng2, I.R. Nabi2, G. Hamarneh1; 1School of Computing Science, Simon Fraser University, Vancouver, BC, 2Cellular Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC B205/P1662 SERS-STORM: A SuperResolution Imaging Technique that Chemically Differentiates Bacterial Cell Surfaces. K.B. Spies1, A.C. Browning1, P. Soneral1, N.C. Lindquist2; 1Department of Biological Sciences, Bethel University, St. Paul, MN, 2Department of Pysics, Bethel University, St. Paul, United States B206/P1663 Two-color fast scanning STED microscopy of live bacteria cells. C.J. Comerci1, S. Saurabh2, A.M. Perez3,4, L. Shapiro4, W.E. Moerner2; 1Biophysics, Stanford University, Stanford, CA, 2 Chemistry, Stanford University, Stanford, CA, 3Biology, Stanford University, Stanford, CA, 4Developmental Biology, Stanford University School of Medicine, Stanford, CA

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Tuesday Poster Session B207/P1664 Superresolution imaging of Drosophila tissues using expansion microscopy. N. Jiang1, H. Kim2, T. Chozinsk2, J. Azpurua3, B.A. Eaton3, J. Vaughan2, J.Z. Parrish1; 1Department of Biology, University of Washington, Seattle, WA, 2Department of Chemistry, University of Washington, Seattle, WA, 3Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX B208/P1665 Pair correlation analysis of Fixed Photoactivatable Localization Microscopy (PALM) and Powerspectral Analysis of Live PALM applied on the Water Channel Aquaporin-3. E.C. Arnspang1,2,3, P. Sengupta1,4, H.H. Jensen5, U. Hahn6, I.T. Andersen6, E.B. Jensen6, K. Mortensen7, J. Lippincott-Schwartz1,4, L.N. Nejsum3; 1The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States, 2Department of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, Odense, Denmark, 3 Department of Clinical Medicine and Interdisciplinary Nanoscience Center, Aarhus University, Aarhus, Denmark, 4 Janelia Research Campus, Ashburn, United States, 5Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark, 6Department of Mathematics, Aarhus University, Aarhus, Denmark, 7 Department of Micro- and Nanotechnology, Technical University of Denmark, Copenhagen, Denmark B209/P1666 Engineering nanobodies for super-resolution imaging and native protein complex isolation. T. Pleiner1, M. Bates2, S. Trakhanov1, C.T. Lee3, J.E. Schliep4, H. Chug1, M. Böhning1, H. Stark4, H. Urlaub3, D. Görlich1; 1Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 2 NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 3 Bioanalytical Mass Spectrometry, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 4Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany B210/P1667 Quantitative analysis of the 3D spatial organization of cells and organelles. J. Chen1, D. Dedham1, A. Walter1, R. Wercberger1, J. Kuhn1, M.A. Le Gros1,2, A. Basbaum1, C.A. Larabell1,2; 1Anatomy, University of California San Francisco, San Francisco, CA, 2Molecular Biophysics Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA

B211/P1668 Single Molecule Tracking of Ace1p In Saccharomyces cerevisiae defines a characteristic residence time for non-specific interactions of transcription factors with chromatin. G.D. Mehta1, D.A. Ball1, R. Salomon-Kent1, D. Mazza2, T. Morisaki3, F. Mueller4, J.G. McNally5, T.S. Karpova1; 1Laboratory of Receptor Biology and Gene Expression, National Institutes of Health, Bethesda, MD, 2Centro di Imaging Sperimentale e Università Vita-Salute San Raffaele, Istituto Scientifico Ospedale San Raffaele, Milano, Italy, 3Department of Biochemistry and Molecular Biology, Colorado State University, Colorado, CO, 4Computation Imaging and Modeling Unit, CNRS, Institut Pasteur, Paris, France, 5Helmholtz Center Berlin, Berlin, Institute for Soft Matter and Functional Materials, Berlin, Germany B212/P1669 Imaging molecular order of dynamic cytoskeletal assemblies in live cells with single molecule sensitivity. S.B. Mehta1, M. McQuilken2, H. Ishii1, P. La Riviere3, P. Occhipinti2, R. Oldenbourg1, A.S. Gladfelter1,2,4, T. Tani1; 1Eugene Bell Center for Regenerative Biology Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA, 2Department of Biological Sciences, Dartmouth College, Hanover, NH, 3Department of Radiology, University of Chicago, Chicago, IL, 4Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC B213/P1670 Real-time subcellular localization reveals hidden intraflagellar transport mechanisms. A.P. Kovacs1, J.M. Kessler1, J. Li2, H. Lin3, S.K. Dutcher3, Y. Wang1,4; 1Physics, Washington University in St. Louis, St. Louis, MO, 2D. E. Shaw Research, New York, NY, 3Genetics, Washington University in St. Louis, St. Louis, MO, 4Physics, Princeton University, Princeton, NJ B214/P1671 Atomic force microscopic (AFM) imaging of cytoskeleton in retinal photoreceptor cells in cryosection. E. Usukura1, A. Narita1, A. Yagi2, S. Ito2, J. Usukura1; 1Structural Biology Center, Nagoya University, Nagoya, Japan, 2 Olympus Corporation, Hachioji, Japan B215/P1672 A genetically-directed, photostable fluoromodule for subdiffraction imaging and single protein tracking in live bacteria. S. Saurabh1, A.M. Perez2, C.J. Comerci3, L. Shapiro2, W.E. Moerner1; 1Chemistry, Stanford University, Stanford, CA, 2Developmental Biology, Stanford University, Stanford, CA, 3 Biophysics, Stanford University, Stanford, CA B216/P1673 Detecting and quantifying single molecules of RNA at the single cell level. M.M. Soruco1, T. Okamoto1, A.V. Orjalo1, B. Meluch1, R.H. Yin1, J.M. Kaplunov1, H.E. Johansson1; 1Genomics, LGC Biosearch Technologies, Petaluma, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B217/P1674 Novel in vitro imaging techniques for understanding mTORC1 signaling. K. Cho1, E. Sydir1, R. Lawrence1, R. Zoncu1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA

New Techniques in Proteomics B218/P1675 Application specific antibody validation. The Human Protein Atlas validation scheme and how to confirm subcellular protein localization. L. Björk1, C. AitBlal1, T.L. Alm1, A. Bäckström1, C. Gnann1, M. Hjelmare1, R. Schutten1, M. Skogs1, C. Stadler1, M. Uhlén1, E. Lundberg1; 1School of Biotechnology, Science for Life Laboratory, KTH—Royal Institute of Technology, Stockholm, Sweden B219/P1676 Purification of Intra-Mitotic Subpopulations from Asynchronous Cells Enables Global Identification of Anaphase Promoting Complex/ Cyclosome (APC/C) Substrates and Their Degradation Timing. T. Ly1, R. Pippa1, A. Whigham2, R. Clarke2, A. Lamond1; 1Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom, 2Centre for Advanced Scientific Technologies, University of Dundee, Dundee, United Kingdom

B221/P1678 Understanding New Aspects of the Mechanism and Biomarkers of Pyrazinamide Resistance in Mycobacterium Tuberculosis. D. Rueda1, P. Sheen1, C. Bernard2, M. Santos1, L. Gandy2, F. Brossier2, V. Pando-Robles3, C. Batista4, N. Veziris2, W. Sougakoff2, M. Zimic1; 1Departamento de Ciencias Celulares y Moleculares, Universidad Peruana Cayetano Heredia, Lima, Peru, 2Centre d’Immunologie et des Maladies Infectieuses, Université Pierre et Marie Curie, Paris, France, 3Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Mexico, 4Laboratorio Universitario de Proteómica, Universidad Nacional Autónoma de Mexico, Mexico DF, Mexico

B222/P1679 Mass-spectrometry of single mammalian cells quantifies proteome heterogeneity during lineage specification. N. Slavov1,2,3, B. Budnik4, E. Levy3; 1Bioengineering, Northeastern University, Boston, MA, 2Proteomics, Broad Institute, Boston, MA, 3Biology, Northeastern University, Boston, MA, 4Systems Biology, Harvard University, Cambridge, MA B223/P1680 A complete removal of genomic DNAs from cell lysate enhances the quality of protein research. S. Hong1, A. Law1, H. Horita1, K. Middleton1; 1RD, Cytoskeleton, Inc., Denver, CO B224/P1681 Novel Neuron Types and Anatomical Organization of the Striatum Revealed by Single-Cell RNA-Seq. G.M. Stanley1, O. Gokce2, B. Treutlein3, S. Quake1, T.C. Sudhof4; 1Bioengineering, Stanford University, Stanford, CA, 2Institute for Stroke and Dementia Research, LudwigMaximilians-Universitat, Munich, Germany, 3 Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, 4Molecular and Cellular Physiology, Stanford University, Stanford, CA B225/P1682 Analyzing mutations in human γD crystallin using high-throughput thermal stability shift assays. I.A. MillsHenry1, C. O’Neil1, K. Piasta2, M.S. KosinskiCollins2; 1Chemistry and Food Science, Framingham State University, Framingham, MA, 2Biology, Brandeis University, Waltham, MA B226/P1683 The Affinity Binder Knockdown Initiative. T.L. Alm1, E. Lundberg1, M. Uhlén1; 1School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden B227/P1684 Proteome-wide cell cycle characterization from fluorescent microscopy images of asynchronous cells. D.P. Sullivan1, D. Mahdessian1, E. Lundberg1, M. Uhlén1; 1Biotechnology, Science for Life Laboratory (KTH), Stockholm, Sweden B228/P1685 Laser capture microdissection and microproteomics: a novel method to study the proteomes of cell protrusions. K. Gousset1, A. Gordon1, S. Kannan1; 1Biology, California State University, Fresno, Fresno, CA B229/P1686 Identification of local GPCR protein networks with sub-minute temporal resolution using proteomics and proximity labeling. B. Lobingier1, R. Hüttenhain2, K. Eichel1, A. Ting3, N. Krogan2, M. von Zastrow1; 1Psychiatry, UCSF, San Francisco, CA, 2Cellular and Molecular Pharmacology, UCSF, San Francisco, CA, 3 Genetics, Stanford University, Stanford, CA B230/P1687 Antibody verification by protein immunoprecipitation and mass spectrometry (IP-MS) demonstrates enrichment of antibody targets and interacting proteins. G.K. Potts1, B.B. Patel1, L.A. Foster1, J. Bucci1, A. Behling1, J.C. Rogers1; 1Protein and Cell Analysis, Thermo Fisher Scientific, Rockford, IL

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B231/P1688 A multiplex quantitative analysis of secreted proteins in bronchoalveolar lavage samples from war veterans with chronic respiratory symptoms. H. Xia1, J.L. Myers1, M.Y. Caballero1, S. Valtier1, A.J. Skabelund2, M.J. Morris2, G.J. Chaudry1; 1Center for Advanced Molecular Detection, Science Technology, 59 Medical Wing, JBSALackland, TX, 2Pulmonary/Critical Care, San Antonio Military Medical Center, JBSA-Ft. Sam Houston, TX

New Techniques in Mechanobiology B232/P1689 Tracking Real Time CellCell, Cell-Matrix and Cell-Biomolecule Interactions during 3D Cell Migration in a Microfluidic Platform. S. Lim1, A. Pavesi1, C. Kuan1; 1AIM Biotech, Singapore, Singapore B233/P1690 Nano-networks of Staphylococcus aureus on hydrophobic micropillars. Z. Jahed1, H. Shahsavan2, M. Verma2, J. Rogowski2, B. Seo2, B. Zhao2, T. Tsui2, F. Gu2, M. Mofrad1; 1Bioengineering, University of California Berkeley, Berkeley, CA, 2Department of Chemical Engineering, University of Waterloo, Waterloo, ON B234/P1691 Response of shape and orientation to cyclic stretch stimulation in cardiomyocytes. C. Nihei1, T. Kaneko1; 1Frontier Bioscience, LaRC, Graduate School of Science and Engineering, Hosei University, Koganei, Japan B235/P1692 Development of cardiotoxicity testing using chick heart tissue pieces on the multi electrode array system. Y. Kamei1, T. Mitsui2, T. Kaneko1; 1Frontier Biosciences, Hosei University, Tokyo, Japan, 2 Department of Physics and Mathematics, Aoyama University, Kanagawa, Japan B236/P1693 Development of a multi-sided polydimethylsiloxane cell growth surface using 3-D printing technology. E. Amaro Gonzalez1, M. Connolly1, A. Parrillo2, R.M. Bellin1; 1Biology, College of the Holy Cross, Worcester, MA, 2Alpert Medical School, Brown University, Providence, RI B237/P1694 Development of new cardiac toxicity testing system to drug discovery. M. Maruyama1, T. Kaneko1; 1Frontier Bioscience, Hosei Univ., Tokyo, Japan B238/P1695 Efficient protein patterning of polyacrylamide hydrogels using photoresist lift-off. A.K. Denisin1,2, J. Moeller1, J. Sim1, R.E. Wilson1, A.J. Ribeiro1, B.L. Pruitt1,3,4; 1Mechanical Engineering, Stanford University, Stanford, CA, 2Bioengineering, Stanford University, Stanford, CA, 3Molecular and Cellular Physiology, Stanford University, Stanford, CA, 4Stanford Cardiovascular Institute, Stanford University, Stanford, CA

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B220/P1677 Improving Split Fluorescent Proteins for Endogenous Protein Labeling. S. Feng1,2, S. Sekine1, V. Pessino1,3, B. Huang1; 1Department of Pharmaceutical Chemistry, University of California in San Francisco, San Francisco, CA, 2Graduate Program in Bioengineering, University of California in Berkeley-UCSF, Berkeley-San Francisco, CA, 3Graduate Program in Biophysics, University of California in San Francisco, San Francisco, CA

Tuesday Poster Session

Board No./Presentation No. B239/P1696 Direct visualization of multinucleated giant cell formation. J.J. Faust1,2, W. Christenson3,4, K. Doudrick5, R. Ros3,4, T.P. Ugarova1,2; 1Center for Metabolic and Vascular Biology, Mayo Clinic, Scottsdale, AZ, 2Molecular and Cellular Biology, Arizona State University, Tempe, AZ, 3Department of Physics, Arizona State University, Tempe, AZ, 4Center for Biological Physics, Arizona State University, Tempe, AZ, 5Department of Civil and Environmental Engineering, University of Notre Dame, Notre Dame, IN B240/P1697 Spatiotemporal control of intracellular phase transitions using light-activated Optodroplets. Y. Shin1, J.M. Berry2, N. Pannucci3, M.P. Haataja2, J.E. Toettcher3, C.P. Brangwynne1; 1Chemical and biological engineering, Princeton University, Princeton, NJ, 2Mechanical Engineering, Princeton University, Princeton, NJ, 3Molecular Biology, Princeton University, Princeton, NJ B241/P1698 Applying A Novel Force Measurement Method Particle Drag Force (PDF) to Quantify Stress FiberIndependent Traction Forces at SubpN Scale. M. Pittman1, S. Park1, Y. Chen1; 1Mechanical Engineering, Johns Hopkins University, Baltimore, MD B242/P1699 Change of beating rate on single cardiomyocytes by focused infrared laser irradiation. M. Ishii1, T. Kaneko1; 1Department of Frontier Bioscience, Hosei University, Tokyo, Japan B243/P1700 Magnetic 3D bioprinting for generating spheroids in high-throughput. G.R. Souza1,2, P. Desai1, H. Tseng1,2, J. Gage1, W. Haisler1; 1Nano3D Biosciences, Inc., Houston, TX, 2Department of Internal Medicine, Division of Oncology, University of Texas Health Science Center at Houston, Houston, TX B244/P1701 Assessment of the biocompatibility of silk-nitride composites with applications as biosensors and osteogenic differentiation on silk films as a potential treatment for bone defects. M. Dittmar1, F. Giginis1, E. Schmidt1, Y. Xue2, D. Jao2, J. Scully1, X. Hu2, C. Iftode1; 1Biological Sciences, Rowan University, Glassboro, NJ, 2 Physics and Astronomy, Rowan University, Glassboro, NJ B245/P1702 Numerical Determination of Wall Shear Stress in Red Blood Cell Membranes. P. Cabrales1, V.P. Jani1, A. Lucas 1, . Munoz 1; 1Bioengineering, University of California San Diego, La Jolla, CA B246/P1703 Mapping cell-to-cell variations in power-law rheology investigated by multifrequency force modulation atomic force microscopy. M. Sawano1, R. Tanaka1, R. Takahashi1, K. KurubayashiShigetomi1, A. Subagyo1, K. Sueoka1, T. Okajima1; 1Hokakido University, Sapporo, Japan

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Tuesday Poster Session

Actin and Actin-Associated Proteins 3 B248/P1704 Characterizing the interaction between microtubule-binding protein, CLIP-170, and actin. Y.O. Wu1,2, E.O. Alberico1, A.G. Madey1, R.A. Miller1, E.J. Jonasson1, H.V. Goodson1,2; 1Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 2Integrated Biomedical Sciences, University of Notre Dame, Notre Dame, IN B249/P1705 Actin and microtubule crosstalk mediate persistent polarized growth. S. Wu1, M. Bezanilla1; 1Biology, University of Massachusetts Amherst, Amherst, MA B250/P1706 Understanding cellular shape modulation and motility – the Actin associated human proteome. D.P. Sullivan1, E. Lundberg1, M. Uhlén1; 1Biotechnology, Science for Life Laboratory (KTH), Stockholm, Sweden B251/P1707 Dictyostelium mechanics accurately identifies new targetable drug space for pancreatic cancer delineated by myosin IIs, filamins, and α-actinins, collectively comprising the mechanobiome. A. Surcel1, E. Schiffhauer1, D. Thomas1, Q. Zhu2, R.A. Anders2, D.N. Robinson1; 1Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD B252/P1708 Myosin IIA and Myosin IIB play distinct roles in metastasis progression of triple-negative breast cancer. H. Park1, C. Choi1, D.M. Helfman1; 1Biological Sciences, Korea Advanced Institute of Science and Technology, Deajeon, Korea, South B253/P1709 Molecular Simulations of Acto-Myosin Network Dynamics. G.A. Papoian1, J. Komianos1, A. Chandrasekaran1; 1Chemistry and Biochemistry, University of Maryland, College Park, MD B254/P1710 Effects of size and shape on the actomyosin network contractile response. I. Scarfone1, A. Michelot2, C. Campillo3, M. Théry1,4, L. Blanchoin1,4; 1CytoMorpho Lab, Biosciences Biotechnology Institute of Grenoble, LPCV, CEA, Grenoble, France, 2IBDM, Aix Marseille Univ, CNRS, Marseille, France, 3 LAMBE, Université d’Evry Val d’Essonne, Paris Evry, France, 4Institut Universitaire d’Hematologie, CytoMorpho Lab, Hôpital Saint Louis, Paris, France

B256/P1712 Non-Muscle Myosin 2 Filament Assembly by Grouped Expansion of Myosin Later than Initial Nucleation (GrEMLIN). J.R. Beach1, K.S. Bruun1, L. Shao2, D. Li2, Z. Swider1, K. Remmert1, Y. Zhang3, M.A. Conti3, R.S. Adelstein3, N.M. Rusan3, E. Betzig2, J.A. Hammer1; 1Cell Biology and Physiology Center, NHLBI, Bethesda, MD, 2Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 3Laboratory of Molecular Cardiology, NHLBI, Bethesda, MD B257/P1713 Intermediate filament and Plakin family function in the morphogenesis of actin-based microridges in zebrafish. Y. Inaba1, V. Chauhan1, A. Sagasti1; 1Department of Molecular, Cell and Developmental Biology,, University of California, Los Angeles, Los Angeles, CA B258/P1714 Non-muscle Myosin II and Rho Kinase play distinct roles in microridge formation and maintenance, sometimes in a single pathway, sometimes in opposition. A.P. van Loon1, A. Sagasti1; 1MBI, University of California, Los Angeles, Los Angeles, CA B259/P1715 Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic ß- or γ-actin. A.R. ORourke1, A. Lindsey2, M.D. Tarpey3, B.J. Perrin4, E.E. Spangenburg3, J.M. Ervasti5; 1Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, 2Physical Medicine and Rehabilitation, University of Minnesota, Minneapolis, MN, 3Physiology, East Carolina University, Greenville, NC, 4Biology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, 5 Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN B260/P1716 Atomic force microscopic (AFM) imaging of muscle sarcomere at high resolution. E. Usukura1, A. Narita1, A. Yagi2, S. Itoh2, J. Usukura1; 1Structural Biology Center, Nagoya University, Nagoya, Japan, 2Olympus Corporation, Tokyo, Japan B261/P1717 Nebulette – Highway connecting actin to desmin in heart cells. G.M. Conover1, H. Herrmann2; 1Biochemistry and Biophysics, Texas AM University, College Station, TX, 2Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, United States B262/P1718 Nucleus-dependent sarcomere assembly is mediated by the LINC complex. A.L. Auld1, E.S. Folker1; 1Biology, Boston College, Chestnut Hill, MA

B255/P1711 LSP-1 is a myosin-IIA binding regulator of podosome dynamics and macrophage migration and invasion. P. Cervero1, C. Wiesner1, A. Booissou2, I. Maridonneau-Parini2, S. Linder1; 1Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Eppendorf, Hamburg, Germany, 2CNRS UMR 5089, Institut de Pharmacologie et de Biologie Structurale, Toulouse, France

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B263/P1719 The Nuclear Function of Tes, an Actin-Binding LIM Protein. R. Vaccaroli1, M. Catillon1, I. Kesisova1, E. Hadzic2, A. Halavatyi2, E. Schaffner-Reckinger1, C. Ampe3, M. Koffa4; 1Cytoskeleton cell plasticity, University of Luxembourg, Esch-sur-Alzette, Luxembourg, 2Cell Biology and Biophysics Unit, EMBL, Heidelberg, Germany, 3 Department of Biochemistry, University of Ghent, Ghent, Belgium, 4Department of Molecular Biology and Genetics, Democritus University of Thrace, Xanthi, Greece B264/P1720 CD2AP in actin-mediated endosome trafficking. I.R. Veland1,2, D. Sumpton1, N.R. Paul1, D.M. Bryant1,3, L.M. Machesky1,3; 1The Cancer Research UK Beatson Institute, Glasgow, United Kingdom, 2BRIC, University of Copenhagen, Copenhagen, Denmark, 3MVLS, Glasgow University, Glasgow, United Kingdom B265/P1721 Cyclophilin A is a novel leading edge protein, regulator of bacterial invasion and crucial component for Listeria cell-to-cell spreading. A.S. Dhanda1, K.E. Warren1, J.A. Guttman1; 1Biological Sciences, Simon Fraser University, Burnaby, BC B266/P1722 SM22 (Transgelin) plays a functional role in bacteria-induced actinrich structures. M.D. Chua1, K.J. Hipolito1, J.A. Guttman1; 1Biological Sciences, Simon Fraser University, Burnaby, BC

B268/P1724 The actin homologue Glucokinase-1 forms actin-like filaments in S. cerevisiae, modulating its enzymatic activity. P.R. Stoddard1, Q.A. Justman2, J.M. Kollman3, E.C. Garner2, A.W. Murray2; 1MCO, Harvard University, Cambridge, MA, 2Center for Systems Biology, Harvard University, Cambridge, MA, 3 Department of Biochemistry, University of Washington, Seattle, WA B269/P1725 Profilins suppress the apoptosis induced by cytoskeletal 15kDaβ-actin in cancer cell lines. N. Ito1, H. Honda1, S. Tone1, M. Tanaka1; 1Life Science and Engineering, Tokyo Denki University, Hatoyama-Machi, Japan B270/P1726 Single actin filament elongation rate and length fluctuations in the presence of profilin. B.G. Horan1, D. Vavylonis1; 1Physics, Lehigh University, Bethlehem, PA B271/P1727 ZBP1 expression is necessary for the epithelial function of MDCK cells. J.L. Davis1, H.Ü. Mücahit1, B.G. Ayee1, G.F. Weber1, A.J. Rodriguez1; 1Biological Sciences, Rutgers University, Newark, NJ

Regulation of Actin Dynamics 2 B272/P1728 How Spire enhances actin assembly by the formin Capu. C.L. Vizcarra1,2, A.O. Bradley1, H. Yoo1, J. Walsh1, M.E. Quinlan1; 1Chemistry and Biochemistry, UCLA, Los Angeles, CA, 2Chemistry, Barnard College, New York, NE B273/P1729 A Novel Actin Filament Sliding and Compaction Mechanism Jointly Catalyzed by Srv2/CAP and its Interacting Partner Abp1. S. Guo1, B.L. Goode1; 1Department of Biology, Brandeis University, Waltham, MA B274/P1730 Dynamical changes of actin filaments of fibroblast and surrounding collagen fibers in 3D collagen gel culture. R. Takabayashi1, T. Kihara1; 1Faculty and graduate School of Environmental Engineering, The university of kitakyusyu, Kitakyusyu, Japan B275/P1731 Intranuclear actin-based motility drives nuclear envelope disruption during baculovirus egress. T. Ohkawa1, M.D. Welch1; 1Molecular and Cell Biology, University of California Berkeley, Berkeley, CA B276/P1732 Cell migration speed is defined by actin mRNA coding sequence. P. Vedula1, S. Kurosaka1, A. Kashina1; 1Biomedical Sciences, University of Pennsylvania, Philadelphia, PA B277/P1733 Remodeling of the F-actin Cytoskeleton in Response to Plasma Membrane Attack by Pore-Forming Toxins. J. Lam1, S.M. Seveau1; 1Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH B278/P1734 Pathogenic E. coli manipulate intracellular actin to drive extracellular motility and cell-to-cell spread. K.B. Velle1, K.G. Campellone1; 1Molecular and Cell Biology, University of Connecticut, Storrs, CT B279/P1735 Alp7A reveals conserved features of actin-based plasmid segregation. N.A. Petek1, A.I. Derman2, J. Royal2, J. Pogliano2, R.D. Mullins1; 1CMP, University of California, San Francisco, San Francisco, CA, 2University of California, San Diego, La Jolla, CA B280/P1736 Form and Function: Distinct Actin Architectures and Nucleators for the Epithelial Plasticity Programs of Embryonic Stem Cell Differentiation and Epithelial to Mesenchymal Transition. F.M. Aloisio1, M. Rana1, D.L. Barber1; 1Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA B281/P1737 G1P3, a mitochondrial antiapoptotic protein augments breast cancer cell metastasis through ROS-mediated actin remodeling. J. Kaur1, A.F. Khalel1, N. Chowdhury1, V. Cheriyath1; 1Biological and Environmental Sciences, Texas AM University-Commerce, Commerce, TX

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B282/P1738 Deciphering the relationship between apical and basal actin fibers with contractile properties of micropatterned myoblasts. C. Bruyere1, S. Gabriele1; 1Mechanobiology Soft Matter group, Interfaces and Complex Fluids Laboratory, Research Institute for Biosciences, CIRMAP, University of Mons, Mons, Belgium B283/P1739 Zinc regulates actin mesh formation in mouse oocyte via Spire2. Y. Jo1, N. Kim1, S. Namgoong1; 1Department of Animal Science, Chungbuk National University, Cheongju, Korea B284/P1740 WHAMM play essential roles in mouse meiotic spindle formation and migration by the controlling actin network near endoplasmic reticulum. Y. Jo1,2, S. Namgoong1, N. Kim1,2; 1Animal science, Chungbuk National University, Cheongju-si, Korea, South, 2BrainKorea 21 Center for Bio-Resource Development, Chungbuk National University, Cheongju-si, Korea, South B285/P1741 Bidirectional Interplay between Vimentin Intermediate Filaments and Actin Stress Fibers. Y. Jiu1, P. Lappalainen1; 1University of Helsinki, Institute of Biotechnology, Helsinki, Finland B286/P1742 Long-tailed class I myosins coordinate actin remodeling during Fc receptor-mediated phagocytosis. S.R. Barger1, S.K. Chandhoke2, M.S. Mooseker2, R.A. Flavell3, M. Krendel1, N.C. Gauthier4; 1State University of New York Upstate Medical University, Syracuse, NY, 2MCDB, Yale University, New Haven, CT, 3Immunobiology, Yale University, New Haven, CT, 4Istituto FIRC di Oncologia Molecolare (IFOM), Milan, Italy B287/P1743 Arginylation dynamically regulates leading edge beta actin during cell migration. I. Pavlyk1, A. Kashina1; 1Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA B288/P1744 Actomyosin network organization in contractile tissue depends on spatiotemporal regulation of myosin II activity. A.C. Wirshing1, E.J. Cram1; 1Biology, Northeastern University, Boston, MA B289/P1745 Actin filament homeostasis, but not actin turnover, is critical for robust actomyosin ring contraction. T. Chew1, J. Huang1, S. Palani1, R. Sommese2, A. Kamnev1, Y. Gu3, S. Oliferenko3, S. Sivaramakrishnan2, M. Balasubramanian1; 1Warwick Medical School, University of Warwick, Coventry, United Kingdom, 2Department of Genetics, Cell Biology, and Development, University of Minnesota, Twin Cities 
Minneapolis, MN, 3Randall Division of Cell and Molecular Biophysics, King’s College London, London, United Kingdom

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TUESDAY

B267/P1723 The actin cytoskeleton of the filamentous fungi Aspergillus fumigatus is resistant to F-actin stabilizing compounds. L.L. LeClaire1, J.R. Fortwendel2; 1Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, 2Clincal Pharmacy, University of Tennessee Health Center, Memphis, TN

Tuesday Poster Session

Board No./Presentation No. B290/P1746 Cellular events mediating extracellular trap formation in neutrophil-like granulocytes. H.R. Thiam1, S.L. Wong2,3, D.D. Wagner2,3,4, C.M. Waterman1; 1National Heart Lung and Blood Institute, National Institute of Health, Bethesda, MD, 2Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, MA, 3Department of Pediatrics, Harvard Medical School, Boston, MA, 4Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA B291/P1747 Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse. C.A. Hartzell1, K.I. Jankowska2,3, J.K. Burkhardt2,3, R.S. Lewis1; 1Molecular and Cellular Physiology, Stanford University, Stanford, CA, 2Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, 3Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA B292/P1748 The regulation of N-WASP activity by phase separation. L.B. Case1, X. Zhang1, J.A. Ditlev1, M.K. Rosen1; 1Department of Biophysics, UT Southwestern Medical Center, Dallas, TX B293/P1749 Characterizing novel ORFs in the regulation of the actin cytoskeleton and mitochondrial quality control during aging. C.N. Sing1, R. Higuchi-Sanabria1,2, A.C. Coughlin1, I.R. Boldogh1, L.A. Pon1; 1Pathology and Cell Biology, Columbia University, New York, NY, 2Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA

Kinesins 2 B295/P1750 Motility and Microtubule Depolymerization Mechanisms of the Kinesin-8 motor, KIF19A. D. Wang1,2, R. Nitta3, M. Morikawa1,2, H. Yajima1,2, S. Inoue1,2, H. Shigematsu3, M. Kikkawa2, N. Hirokawa1,2,4; 1Department of Molecular Structure and Dynamics, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, 2Depatment of Cell Biology and Anatomy, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan, 3 Center for Life Science Technology, RIKEN, Yokohama, Japan, 4Center of Excellence in Genome Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia B296/P1751 Eg5 inhibitors have contrasting effects on microtubule stability and spindle integrity. G. Chen1, Y. Kang1, A.S. Gayek2, R. Ohi2, W.O. Hancock1; 1Biomedical Engineering, Pennsylvania State University, University Park, PA, 2Cell and Developmental Biology, Vanderbilt University, Nashville, TN

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Tuesday Poster Session B297/P1752 Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly. W. Wang1,2, X. Liu1,2, P. Yao1, X. Wang2, H. Wang2, X. Yao1,2; 1Morehouse School of Medicine Georgia Cancer Coalition, Atlanta, GA, 22Anhui Key Laboratory for Cellular Dynamics Chemical Biology, Hefei, China B298/P1753 Regulation of the mitotic motor Eg5 by Casein Kinase 2 (CK2) suggests important pathway opposing small molecule cancer drug treatment in vitro and in cells. D.E. Chapman1, M. Mattson-Hoss1, J. Xu1, Y. Jun1, J. Muretta2, S. Rosenfeld3, S.P. Gross1; 1Developmental and Cell Biology, University of California Irvine, Irvine, CA, 2Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, 3Cleveland Clinic, Cleveland, OH B299/P1754 Polar ejection force generation by the “non-motile” chromokinesin NOD. A.A. Ye1,2, T.J. Maresca1,2; 1Molecular and Cellular Biology Graduate Group, University of Massachusetts Amherst, Amherst, MA, 2Biology Department, University of Massachusetts Amherst, Amherst, MA B300/P1755 The stalk region of Kid is required to turn off the polar ejection force generation at anaphase, thereby facilitating chromosome segregation. S. Soeda1, K. Yamada-Nomoto2, M. Ohsugi1; 1Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Meguro-Ku, Tokyo, Japan, 2Department of Obstetrics and Gynecology, The University of Toyama,, Toyama city, Toyama, Japan B301/P1756 Kinesin-1-dependent nucleus positioning is required for directed cell migration. B. Latgé1, P. Maiuri1, B. Goud1, K. Schauer1; 1UMR144 Subcellular Structure and cellular Dynamics, Institut Curie, PSL Research University, CNRS, Paris, France B302/P1757 The role of Kinesin-II and Intraflagellar transport complex A (IFTA) in canonical Wnt signaling independent of their role in the cilium in Drosophila. L.T. Vuong1; 1) Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, United States B303/P1758 Multiple kinesin-14 family members provide the retrograde transport mechanism in plants. M. Yamada1, K. Ariga1, Y. Tanaka-Takiguchi1, M. Nishina1, G. Goshima1; 1Biological science, Nagoya University, Nagoya, Japan B304/P1759 A novel isoform of Drosophila non-muscle Tropomyosin interacts with Kinesin-1 and functions in mRNA localization. D. Boggupalli1, R. Veeranan-Karmegam1, G. Liu1, G.B. Gonsalvez1; 1Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA

B305/P1760 Microtubule-microtubule sliding by kinesin-1 is essential for normal cytoplasmic streaming in Drosophila oocytes. W. Lu1, M. Winding1, M. Lakonishok1, J. Wildonger2, V.I. Gelfand1; 1Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2 Department of Biochemistry, University of Wisconsin-Madison, Madison, WI B306/P1761 Kinetics of nucleotidedependent structural transitions in the kinesin-1 mechanochemical cycle. K.J. Mickolajczyk1, W.O. Hancock1; 1Biomedical Engineering, Penn State University, University Park, PA B307/P1762 Altered Mechanical Properties of Kinesins With Mutations That Cause Hereditary Spastic Paraplegia. L. Prophete1, C. Kelland1, L. Thornton1, K. Gilmore1, T.M. Huckaba1; 1Biology, Xavier University of Louisiana, New Orleans, LA B308/P1763 Direct measurement of the binding rate constant of kinesin to microtubules in living cells. T. Kambara1, Y. Okada1; 1Quantitative Biology Center, RIKEN, Suita, Japan B309/P1764 KIF18B is regulated by distinct interactions in the tail domain. S. Shrestha1, A.L. Yount1, S.C. Ems-McClung1, C.E. Walczak1; 1Medical Science Program, Indiana University, Bloomington, IN

Dynein B310/P1765 Two Alternative Modes of Dynein Regulation by LIS1. M.E. DeSantis1, Z. Htet1, M. Cianfrocco1, P.T. Tran1, A.E. Leschziner1, S.L. ReckPeterson1; 1CMM, UCSD, La Jolla, CA B311/P1766 Mutations in dynein’s stalk reveal hotspots that impact motility. S. Niekamp1, G. Bhabha1, N. Zhang2, R.D. Vale2; 1Cellular and Molecular Pharmacology, University of California - San Francisco, San Francisco, CA, 2Cellular and Molecular Pharmacology, University of California - San Francisco / HHMI, San Francisco, CA B312/P1767 Cooperative accumulation of processive dynein-dynactin complexes drives the clustering and focusing of microtubule minus-ends. R. Tan1, R.J. McKenney1; 1Molecular and Cellular Biology, University of California - Davis, Davis, CA B313/P1768 Dynamics of cortical dynein in mitosis. P. Wadsworth1, H. Jordan1; 1Biology, University of Massachusetts, Amherst, MA B314/P1769 Intracellular logistics of LIS1 and cytoplasmic dynein in lissencephaly. M. Yamada1; 1Molecular Bio-signaling, University of Fukui, Yoshida-gun, Fukui, Japan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B315/P1770 A pathogenic dynactin variant suppresses cell migration by inhibiting integrin recycling. T. Yeh1, E. Kahney1, T.A. Schroer1; 1Biology, Johns Hopkins University, Baltimore, MD B316/P1771 Cortical dynein attachment molecule Num1 regulates dynein pulling mechanism based on its distribution at the cell cortex. S. Omer1, W. Lee1; 1Biology, University of Massachusetts, amherst, Amherst, MA B317/P1772 She1 affects dynein motility through simultaneous and direct interactions between the microtubule and the dynein microtubule-binding domain. K. Ecklund1, L.G. Lammers1, S.M. Markus1; 1Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B318/P1773 RILP is a stress-activated dynein recruitment factor required for mammalian autophagosome biogenesis, maturation and transport. N.V. Khobrekar1,2, R.B. Vallee2; 1Department of Biological Sciences, Columbia University, New York, NY, 2Department of Pathology and Cell Biology, Columbia University, New York, NY B319/P1774 Motor and Auto-Inhibitory Traits of Dynein-2 Reveal a Basis for Cyclic Intraflagellar Transport. K. Toropova1, M. Mladenov1, A.J. Roberts1; 1Institute of Structural Molecular Biology, Birkbeck, London, United Kingdom

B321/P1776 Characterization of a mouse model carrying a CMT2O dynein heavy chain mutation. S. Nandini1, J. Conley1, T. Sabblah1, A. Ghersi1, N. Wilson1, R. Love1, L. King1, S.J. King1; 1Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL B322/P1777 NMJ Analysis in a CMT2O Mouse Model with a Dynein Heavy Chain Mutation. T.T. Sabblah1, A. Ledray1, J. Pasos1, R. Love1, S.J. King1; 1Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL B323/P1778 Application of the fluctuation theorem to the non-invasive force measurement during the transport of pigment granules in melanocytes. S. Hasegawa1, K. Ikeda2, T. Sagawa3, Y. Okada2,4, K. Hayashi1,5; 1Tohoku University, Sendai, Japan, 2Quantitative Biology Center, RIKEN, Suita, Japan, 3Information and Communications Technology, Kobe, Japan, 4 The University of Tokyo, Tokyo, Japan, 5 AMED・PRIME, Tokyo, Japan

B324/P1779 Regulation of the balance between microtubule plus-end localisation and minus-directed motion of human dynein. R. Jha1, J. Roostalu1, M. Trokter1, T. Surrey1; 1Lincoln’s Inn Fields Laboratory, The Francis Crick Institute, London, United Kingdom B325/P1780 Dynamic control of dynein localization in mitosis. J.K. Monda1,2, I.M. Cheeseman1,2; 1Whitehead Institute for Biomedical Research, Cambridge, MA, 2 Biology, MIT, Cambridge, MA B326/P1781 Regulation of the Dynein Adaptor Bicaudal D2 and Its Role in Spinal Muscular Atrophy. W. Huynh1, R.D. Vale1; 1Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA

Tubulin and Associated Proteins B328/P1782 An image-based view of the microtubule proteome. F. Danielsson1, M. Skogs1, L. Åkesson1, D. Mahdessian1, D.P. Sullivan1, P. Thul1, M. Wiking1, L. Björk1, R. Schutten1, C. AitBlal1, M. Hjelmare1, C. Gnann1, M. Uhlén1, E. Lundberg1; 1Proteomics, KTH Royal Institute of Technology, Stockholm, Sweden B329/P1783 Effects of HDAC5 and aTAT1 expression on axon regeneration in adult neurons. S. Lin1, N. Sterling1, I. Junker1, G.M. Smith1; 1Shriners Research Center for Neural Regeneration and Neural Rehabilitation, Temple University, Philadelphia, PA B330/P1784 Tau influences the stability of axonal microtubules in an unexpected fashion: implications for development and disease. T.O. Austin1, P.W. Baas1, L. Qiang1, D.C. Jean2; 1Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 2American Association for the Advancement of Science, National Science Foundation, Washington, DC B331/P1785 Deregulation of tubulin polyglutamylation induces neurodegeneration. M.M. Magiera1,2,3,4, S. Bodakuntla1,2,3,4, M. Lutz5, A. Calas6, T. Hausrat7, P. Catarino Marques Sousa1,2,3,4, M. Kneussel7, M. Landry6, T. Harkany8, G.G. Kovacs5, C. Janke1,2,3,4; 1Universite ParisSaclay, Saclay, France, 2PSL Research University, Paris, France, 3Genotoxic stress and cancer, CNRS, Orsay, France, 4 Genotoxic stress and cancer, Institut Curie, Orsay, France, 5Institute of Neurology, Medical University, Vienna, Austria, 6 Interdisciplinary Institute for Neuroscience, Université Bordeaux/ CNRS UMR 5297, Bordeaux, France, 7Zentrum für Molekulare Neurobiologie, University of Hamburg, Hamburg, Germany, 8Department of Molecular Neurosciences, Center for Brain Research, Medical University, Vienna, Austria

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B332/P1786 Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations. X. Sun1, J.H. Park2, A. RollMecak2, T. Li1; 1NEI, NIH, Bethesda, MD, 2 NINDS, NIH, Bethesda, MD B333/P1787 Near-atomic cryo-EM structural studies of microtubules, microtubulestabilizers, and microtubule-associated proteins. E.H. Kellogg1, S. Howes2, N.M. Hejab1, S. Ti3, E. Ramírez-Aportela4, P. Northcote5, J.H. Miller5, J. Díaz6, K.H. Downing1, T.M. Kapoor3, P. Chacón4, E. Nogales1,7; 1Molecular Biophysics and Integrative Bioimaging, UC Berkeley, Berkeley, CA, 2Molecular and Cellular Biology, Leiden University Medical Center, Leiden, Netherlands, 3Chemical and Cell Biology, Rockefeller University, New York, NY, 4Biological Physical Chemistry, Rocasolano Physical Chemistry Institute, Madrid, Spain, 5Centre for Biodiscovery, Victoria University of Wellington, Wellington, New Zealand, 6Chemical and Physical Biology, Centro de Investigaciones Biológicas, Madrid, Spain, 7Howard Hughes Medical Institute, Berkeley, CA B334/P1788 The TOG protein STU2/ XMAP215 interacts with SUMO. M. Greenlee1, A. Alonso1, M. Rahman1, N. Meednu2, S. Morris1, R.K. Miller1; 1Dept of Biochemistry, Oklahoma State University, Stillwater, OK, 2Dept of Biology, University of Rochester, Rochester, NY B335/P1789 The role of multiple TOG domains in XMAP215/Dis1’s MT polymerase function. B.D. Cook1, S. Nithianantham1, J.M. Al-Bassam1; 1Molecular and Cellular Biology, University of California, Davis, Davis, CA B336/P1790 Structural and biochemical characterization of CLASP TOGs. S. Majumdar1, L.M. Rice1; 1Biophysics, UT Southwestern Medical Center, Dallas, TX B337/P1791 Arl4D acts with EB1 to regulate microtubule plus-end dynamics at the centrosome. S.J. Lin1, C.f. Huang1, T.S. Wu1, C.C. Li1, F.J. Lee1,2; 1Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, 2 Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan B338/P1792 GSK3β-elicited competition between SKAP and Kif2b at the kinetochore microtubule ensures accurate chromosome segregation. B. Qin1, D. Cao1, H. Wu1, W. Wang1,2, X. Liu1,2, C. Fu1,2, X. Yao1,2; 1Anhui Key Laboratory of Cellular Dynamics and Chemical Biology, University of Science Technology of China, Hefei, China, 2Center of Excellence on Molecular Cell Sciences, Chinese Academy of Sciences, Hefei, China B339/P1793 Septin-microtubule interplay enables initiation of branching morphogenesis. D.K. Bogorodskaya1, L. Ligon1; 1Biology, Rensselaer Polytechnic Institute, Troy, NY

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B320/P1775 Dynein destabilizes its microtubule track: evidence for regulating dynein transport through negative feedback. C.E. Estrem1, J.K. Moore1; 1Cell and Development, University of Colorado Anshutz Medical Campus, Aurora, CO

Tuesday Poster Session

Board No./Presentation No. B340/P1794 A role for the yeast CLIP170 ortholog, the plus-end-tracking protein Bik1, and the Rho1 GTPase in Snc1 trafficking. C. Boscheron1, F. Caudron2, E. Denarier1, L. Aubry1, A. Andrieux1; 1Grenoble Insitut of neurosciences, Université Grenoble Alpes, Grenoble, France, 2Randall Division of Cell Molecular Biophysics, King’s College London, London, United Kingdom B341/P1795 Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases. S. Nithianantham1, B.D. Cook1, F. Chang2,3, J. Al-Bassam1; 1Molecular and Cellular Biology, University of California, Davis, CA, 2 Department of Cell and Tissue Biology, University of California, San Francisco, CA, 3Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY B342/P1796 Electrostatic regulation of microtubule crosslinking during spindle assembly and elongation. A. Ismael1, J.E. Aiken1, J.K. Moore1; 1Cell and Developmental Biology, University of Colorado, Anschutz Medical Campus, Aurora, CO B343/P1797 Molecular Pathogenesis of Tubulin Disorders During Neural Development. J.E. Aiken1, D. Mitchell2, E. Bates2, J.K. Moore1; 1Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, 2Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO B344/P1798 Implication of tubb6, a minor beta-tubulin isotype, in muscle defects of the mdx mouse model of Duchenne muscular dystrophy. D. Randazzo1, U. Khalique1, D.M. Talsness 2, J.J. Belanto2, K.J. Zaal1, M.D. Tran1, A. Kenea1, D.L. Sackett3, J.M. Ervasti2, E. Ralston1; 1Light Imaging Section, Office of Science and Technology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 2 Department of Biochemistry, Molecular Biology, and Biophysics, and Program in Molecular, Cellular, Developmental Biology, and Genetics, University of Minnesota-Twin Cities, Minneapolis, MN, 3Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD

Microtubule Dynamics and Its Regulation 2 B345/P1799 Rapid control of microtubule plus end interactions and dynamics by light. J. van Haren1, A.W. Ettinger1, H. Wang2, K.M. Hahn2, T. Wittmann1; 1Department of Cell Tissue Biology, UCSF, San Francisco, CA, 2 Department of Pharmacology, UNC Chapel Hill, Chapel Hill, NC

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Tuesday Poster Session B346/P1800 Optogenetic Control of Microtubule-Actin Crosslinking. R.C. Adikes1, B.F. Saway1, R.A. Hallett2, B. Kuhlman2, K.C. Slep1; 1Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC B347/P1801 DRG1: an unusual GTPase that binds and severs microtubules. A. Schellhaus1, D. Moreno-Andrés1, M. Chugh2, H. Yokoyama1, E. Schaeffer2, W. Antonin1; 1Friedrich Miescher Laboratory of the Max Planck Society, Tuebingen, Germany, 2Zentrum für Molekularbiologie der Pflanzen, Eberhard-Karls-Universität, Tuebingen, Germany B348/P1802 Fidgetin-like 2, a microtubule severing enzyme, is a novel regulator of angiogenesis and heart regeneration. A.H. Kramer1, R. Charaffedine1, B. O Rourke1, Y. Wang1, J. Nosanchuk1, R. Kitsis 1, J.M. Friedman1, B. Zhou1, D.J. Sharp1; 1Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY B349/P1803 Polarized endosome dynamics by spindle asymmetry during asymmetric cell division. E. Derivery1,2, C. Seum2, A. Daeden2, S. Loubéry2, L. Holtzer1, F. Julicher3, M. Gonzalez-Gaitan2; 1Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom, 2 Biochemistry, University of Geneva, Geneva, Switzerland, 3Max Planck Institute for the Physics of Complex Systems, Dresden, Germany B350/P1804 Spindle force measurements using hydrogel micro-cantilevers. T. Sulerud1; 1MCLS, University of Wyoming, Laramie, WY B351/P1805 Mechanism of Microtubule Dynamics Regulation by the drug Colchicine. M. Hemmat1, D.J. Odde2, B.T. Castle2; 1Mechanical Engineering, University of Minnesota, Minneapolis, MN, 2Biomedical Engineering, University of Minnesota, Minneapolis, MN B352/P1806 Reconstitution of Microtubule Dynamics from Budding Yeast Lysate. Z.J. Bergman1, J. Wong1, D.G. Drubin1, G. Barnes1; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA B353/P1807 DRG2 is implicated in microtubule dynamics. I. Han1, D. Thi Thao1, S. Jang1, J. Park1; 1Biological Sciences, University of Ulsan, Ulsan, Korea, South B354/P1808 The TACC protein family and their unique regulation of the dynamic microtubule plus-end. G. Cammarata1, B. Erdogan1, E.L. Rutherford1, P. Ebbert1, L.A. Lowery1; 1Biology, Boston College, Chestnut Hill, MA

B355/P1809 Elevated ATP/ADP ratio destabilizes the microtubule network to facilitate insulin secretion in pancreatic beta cells. K. Ho1, G. Gu1, I. Kaverina1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN B356/P1810 Treadmilling of microtubules drives the directional transport of maternal mRNAs in fertilized ascidian eggs. H. Ishii1, T. Tani1; 1Eugene Bell Center, Marine Biological Laboratory, Woods Hole, MA B357/P1811 Drosophila kinesin-8 has a microtubule depolymerisation activity and is required for stable kinetochoremicrotubule attachment. T. Edzuka1,2, G. Goshima1,2; 1Marine Biological Laboratory (MBL), Woods Hole, MA, 2Division of Biological Science, Nagoya University, Nagoya, Japan B358/P1812 Using computational models to study treadmilling behavior of microtubules and other steadystate polymers. J.P. Scripture1, E.C. Norby1, E.J. Jonasson1, C. Li2, S.M. Mahserejian2, A.J. Mauro2, M.S. Alber2, H.V. Goodson1; 1Chemistry and Biochemistry, University of Notre Dame, South Bend, IN, 2 Applied and Computational Mathematics and Statistics, University of Notre Dame, South Bend, IN B359/P1813 Elucidating the Role of a Human β-tubulin, TUBB4B: Functional Analysis of a Novel Patient-Derived Mutation. S.M. Schreiner1, D.L. Sackett2, J.K. Moore1; 1Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, 2Program in Physical Biology, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD B360/P145 Microtubule dynamics sense and respond to ECM density to regulate matrix metalloprotease-14 trafficking and localization. A. Braun1, P. Singh1, K.A. Myers1; 1Biology, University of the Sciences in Philadelphia, Philadelphia, PA

Ciliary Formation and Trafficking B361/P1814 Intraflagellar transport protein tip remodeling and motor dynamics revealed with a photobleaching gate. A. Chien1, S. Shih1, R. Bower2, M.E. Porter2, A. Yildiz1; 1BioPhysics, UC Berkeley, Berkeley, CA, 2Genetics, University of Minnesota, Minneapolis, MN B362/P1815 Dynein-2 requires HSP90 chaperone activity to ensure robust retrograde IFT and ciliogenesis. T.J. Dantas1, N.V. Khobrekar1,2, R.B. Vallee1; 1Pathology and Cell Biology, Columbia University, New York, NY, 2 Biological Sciences, Columbia University, New York, NY

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B363/P1816 Chlamydomonas IFT54 is required for flagellar assembly. X. Zhu1, Y. Liang1, J. Pan1,2; 1School of Life Sciences, Tsinghua University, Beijing, China, 2Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong Province, China B364/P1817 Flagellar length synchronization in Chlamydomonas. S. Dutta1, P. Avasthi1,2; 1Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, 2Ophthalmology, University of Kansas Medical Center, Kansas City, KS B365/P1818 Flagellar length regulation in the intestinal parasite Giardia lamblia. S.G. McInally1, S.C. Dawson1; 1Microbiology and Molecular Genetics, University of California, Davis, Davis, CA B366/P1819 Ciliary PI(4,5)P2 dictates fall of primary cilia and rise of cell cycle. S.C. Phua1, T. Inoue1; 1Cell Biology, Johns Hopkins University, Baltimore, MD B367/P1820 The Glial Actin Cytoskeleton Regulates Neuronal Ciliogenesis in C. elegans. Y. Zhang1, H. Zhu1, G. Ou1; 1life science, Tsinghua University, Beijing, China B368/P1821 Jasplakinolide-induced cell rounding provokes ciliogenesis. T. Nagai1, K. Mizuno1; 1Graduate School of Life Sciences, Tohoku University, Sendai, Japan

B370/P1823 The centriolar satellite protein CEP109 and CEP290 interact and are required for recruitment of BBS proteins to the cilium. D. Conkar1, E. Culfa1, E. Odabasi1, N. Rauniyar2, J. Yates iii2, E.N. Firat-Karalar1; 1Molecular Biology and Genetics, Koc University, Istanbul, Turkey, 2 Department of Chemical Biology, The Scripps Research Institute, La Jolla, CA B371/P1824 Defining Centriole Function In C. elegans Cilia Assembly. D. Serwas1, A. Dammermann1; 1Max F. Perutz Laboratories, University of Vienna, Vienna, Austria B372/P1825 The distal appendage protein CEP164 is critical for embryonic development and multiciliated cell differentiation. S.S. Siller1,2,3, H. Sharma1,2,3, F. Li2, M.J. Holtzman4, H. Colognato1,2,3, B.C. Holdener5, K. Takemaru1,2,3; 1Graduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, NY, 2Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, 3Medical Scientist Training Program, Stony Brook University, Stony Brook, NY, 4Department of Medicine, Washington University School of Medicine, St. Louis, MO, 5Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY

B373/P1826 A Novel Mechanism Regulating Centriole Maturation in Quiescent Cells. E. Betleja1, K. Shim1, B. Wang2, M.R. Mahjoub1; 1Nephrology Division, Washington University School of Medicine, Saint Louis, MO, 2Genetic Medicine, Weill Medical College of Cornell University, New York, NY B374/P1827 Growth factor signaling regulation of a Rab-effector switch required for ciliogenesis initiation. V. Walia1, M. Vetter2, C. Insinna1, Q. Lu1, D. Ritt1, S. Specht1, J. Stauffer1, D. Morrison1, E. Lorentzen2, C.J. Westlake1; 1Center for Cancer Research, National Cancer Institute, Frederick, MD, 2Max Plank Institute of Biochemistry, Martinsried, Germany B375/P1828 TULP3 and Tubby function as general adapters for trafficking of structurally diverse integral membrane proteins to the primary cilium. H.B. Badgandi1, S. Hwang1, I. Shimada1, S. Mukhopadhyay1; 1Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX B376/P1829 The ciliary trafficking of a group of membrane proteins is dependent on the ternary complex comprising transportin1, Rab8 and the ciliary targeting signal. L. Lu1, V. Madugula1; 1School of Biological Sciences, Nanyang Technological University, Singapore, Singapore B377/P1830 A possible role for endocytosis in signaling-regulated trafficking of a membrane protein from the plasma membrane into the ciliary membrane of existing cilia in Chlamydomonas. P. Ranjan1,2, W.J. Snell1,2; 1Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 2Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX B378/P1831 An ancient origin for IFTdependent transport of rhodopsins: Chlamydomonas Channelrhodopsin I and Chlamyopsin 8 localize to the eyespot and to cilia, and trafficking to both organelles requires IFT. M. Awasthi1,2, P. Ranjan1,2, K. Sharma1, S.K. Veetil1, W.J. Snell2, S. Katerina1; 1Biochemistry, University of Delhi South Campus, New Delhi, India, 2Cell Biology and Molecular Genetics, University of Maryland, College Park, MD B379/P1832 Novel ciliary gene, Thm2, interacts with Thm1 to regulate skeletal, sperm and forebrain development. B.A. Allard1,2, L.M. Silva1,2, D.T. Jacobs1,2, G. Sanchez1,3,4, G. Blanco1,3,4, J.L. Vivian3,5, P.V. Tran1,2; 1Kidney Institute, University of Kansas Medical Center, Kansas City, KS, 2 Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, 3Institute for Reproductive Health and Regenerative Medicine, University of Kansas Medical Center, Kansas City, KS, 4Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, 5 Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B380/P1833 Regulation of ciliary retrograde protein trafficking by Joubert syndrome proteins Arl13b and INPP5E. S. Nozaki1, Y. Katoh1, K. Nakayama1; 1Pharmaceutical Sciences, Kyoto University, Kyoto, Japan B381/P1834 The ESCRT protein VPS4 is involved in ciliogenesis. C.M. Ott1, D. Nachmias2, S. Adar2, S. Sherman2, J. Lippincott-Schwartz1, N. Elia2; 1Janelia Research campus, Ashburn, MD, 2Life Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel B382/P1835 Inhibition of nuclear import regulates flagellar length in Chlamydomonas reinhardtii. S. Huang1, P. Avasthi1,2; 1Ophthalmology, University of Kansas Medical Center, Kansas City, KS, 2 Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS B383/P1836 The function of the basal body microtubules associated with intraflagellar transport (IFT). Y. Koiso1, S. Yamaguchi1, M. Sugawa1, T. Kobayashi1, Y.Y. Toyoshima1, J. Yajima1; 1Department of Life Sciences Graduate School of Art & Sciences, The University of Tokyo, Tokyo, Japan B384/P1837 A Novel Interaction Between Kinase and Phosphatase Activities in Regulation of Cilia Formation in ARPE-19 Cells. A.O. Sperry1; 1Department Anatomy & Cell Biology, East Carolina Univ-Brody School of Medicine, Greenville, NC B385/P1838 FHDC1 acts at the subdistal appendages to regulate cilia assembly. S.J. Copeland1, A.S. McRae1, J.W. Copeland1; 1Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON B386/P1839 Caveolin-1 localizes to the ciliary transition zone in a KIF13Band NPHP4-dependent manner and is required for ciliary accumulation of Smoothened. K.B. Schou1, J.B. Mogensen1, S.K. Morthorst1, B. Nielsen1, N. Fürstenberg1, S. Saunier2,3, A. Bizet2,3, S.T. Christensen1, L.B. Pedersen1; 1Department of Biology, University of Copenhagen, Copenhagen, Denmark, 2Laboratory of Hereditary Kidney diseases, Inserm UMR1163, Paris, France, 3Imagine Institut, Paris Descartes Sorbonne Paris Cité University, Paris, France B387/P1840 RAB-28, linked to retinal degeneration, associates with the BBSome and intraflagellar transport in C. elegans. S.P. Carter1, V.L. Jensen2, A.A. Sanders1, J. Kennedy 1, B. Kennedy1, M.R. Leroux2, O.E. Blacque1; 1School of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Republic of Ireland, 2Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC

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TUESDAY

B369/P1822 Investigating Actin Redundancy in Chlamydomonas reinhardtii Flagellar Assembly. A.L. Tetlow1, D.M. Mueller1, P. Avasthi1,2; 1Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, 2Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS

Tuesday Poster Session

Board No./Presentation No. B388/P1841 Cilia-related roles for endosome maturation regulators Rabenosyn-5 and VPS45 in C. elegans. N. Scheidel1, J. Kennedy 1, O.E. Blacque1; 1University College Dublin, UCD Conway Institute of Biomolecular and Biomedical Research, Dublin, Republic of Ireland B389/P1842 The N-terminal 60-residues and membrane anchoring of phospholipase D are sufficient for transport and ciliary export by the BBSome/IFT system in Chlamydomonas. P. Liu1, K.F. Lechtreck1; 1Department of Cellular Biology, University of Georgia, ATHENS, GA

Cytokinesis 2 B401/P1843 Nanoscale architecture of Cdc15 and the S. pombe contractile ring. N.A. McDonald1, S.E. Smith2, R. Li3, K.L. Gould1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2 Stowers Institute for Medical Research, Kansas City, MO, 3Cell Biology, Johns Hopkins University, Baltimore, MD B402/P1844 Septin-binding protein Bni5 reorganizes yeast septin filament structure. S.M. Sterling1, E.A. Booth1, D. Dovala2, E. Nogales1,3,4, J.W. Thorner1; 1Division of Biochemistry, Biophysics, and Structural Biology, Department of Molecular and Cellular Biology, University of California, Berkeley, CA, 2Program in Microbial Pathogenesis and Host Defense, Department of Microbiology and Immunology, University of California, San Francisco, CA, 3Life Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 4Howard Hughes Medical Institute, Chevy Chase, MD B403/P1845 Unravelling the Role of Adaptor Proteins Cin85 and CD2AP in Septin-mediated Cytokinesis. . Safavian1, K. Fung1, W.S. Trimble1; 1Department of Biochemistry, University of Toronto, Toronto, ON B404/P1846 Node-mediated and backup pathways in contractile ring assembly. T.C. Bidone1,2, N. Wang3, J. Wu3, D. Vavylonis1; 1Physics, Lehigh University, Bethlehem, PA, 2Chemistry, The University of Chicago, Chicago, IL, 3Molecular Genetics, The Ohio State University, Columbus, OH B405/P1847 Evaluating the Combined Roles of Blt1p and Gef2p in Sid2p/ Mob1p Localization to the Contractile Ring During Fission Yeast Cytokinesis. J.W. Goss1, L. Kwon1; 1Biological Sciences, Wellesley College, Wellesley, MA B406/P1848 Membrane composition is important in contractile ring anchoring in Schizosaccharomyces pombe. C.E. Snider1, A.H. Willet1, J. Chen1, K.L. Gould1; 1Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN

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Tuesday Poster Session B407/P1849 Cdc42 GEF Gef1 promotes uniform protein organization along the cytokinetic ring to enable concentric furrowing. B. Wei1, J. Habiyaremye1, P. Mlynarczyk2, S. Abel2, M. Das1; 1Biochemistry Cellular and Molecular biology, University of Tennessee, Knoxville, TN, 2Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN B408/P1850 Cytoskeletal crosslinkers both drive and brake cytokinetic ring closure. C. Patino Descovich1, D.B. Cortes2, S. Ryan2, M. Werner2, L. Zhang3, K.N. Rehain2, P.S. Maddox2, A.S. Maddox2; 1Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC B409/P1851 Constriction mechanism of the actomyosin ring. L.T. Nguyen1, M.T. Swulius1, M. Mishra2, G.J. Jensen1; 1Biology Bioengineering, California Institute of Technology, Pasadena, CA, 2Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India B410/P1852 Back-to-back mechanisms drive actomyosin ring contraction during Drosophila embryo cleavage. Z. Xue1, A.M. Sokac1; 1Verna Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX B411/P1853 Component turnover in the cytokinetic ring maintains organizational homeostasis and tension production. S. Wang1, S. Thiyagarajan1, T.G. Chew2, J. Huang2, S. Palani2, A. Kamnev2, Y. Gu3, S. Oliferenko3, M. Balasubramanian2, B. O’Shaughnessy4; 1Physics, Columbia University, New York, NY, 2Biomedical Sciences, University of Warwick, Coventry, United Kingdom, 3King’s College London, Randall Division of Cell and Molecular Biophysics, London, NY, 4Chemical Engineering, Columbia University, New York, NY B412/P1854 Fission yeast contractile ring tension increases ~2-fold as the ring constricts, but the tension regulates septum closure and does not set the rate of constriction. S. Thiyagarajan1, H. Chin2,3, E. Karatekin4, T.D. Pollard2,5,6, B. O’Shaughnessy3; 1Physics, Columbia University, New York, NY, 2Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, 3Chemical Engineering, Columbia University, New York, NY, 4Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, 5 Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 6Cell Biology, Yale University, New Haven, CT

B413/P1855 Cortical flow into the contractile ring drives exponential increases in myosin concentration and constriction rate during cytokinetic ring closure. R. Khaliullin1, R.A. Green1, L. Shi2, M. Berns2, J.S. Gomez Cavazos1, A.B. Desai1, K. Oegema1; 1Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, 2Department of Bioengineering and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA B414/P1856 Myosin efflux promotes adaptive cell elongation to coordinate chromosome segregation with cell cleavage. E. Montembault1, m. Claverie1, L. Bouit1, C. Landmann1, C. Cabernard1, A. Royou1; 1IECB, PESSAC, France B415/P1857 Polarized Actin Polymerization Enlarges Daughter Cell Asymmetry. D. Tian1, Y. Chai1, Z. Zhu1, G. Ou1; 1School of Life Sciences, Tsinghua University, Beijing, China B416/P1858 Effects of cell size and shape on cleavage furrow ingression in sea urchin cytokinesis. B. Knapp1, M. Bennett2, Z. Zhou1, N. Minc3, F. Chang1, D.R. Burgess2; 1Cell and Tissue Biology, University of California San Francisco, San Francisco, CA, 2Biology, Boston College, Chestnut Hill, MA, 3CNRS, Institut Jacques Monod, Paris, France B417/P1859 Defining a cell’s internal compass: Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. N. Taneja1, A.M. Fenix1, L. Rathbun2, B.A. Millis1, M.J. Tyska1, H. Hehnly2, D.T. Burnette1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY B418/P1860 EBP50 is localized at the blebs and phosphorylated at Serine 347-348 residues in mitotic cells. H. Lim1, T. Jou1; 1Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan B419/P1861 Visualizing direct interactions in the mechanobiome. P. Kothari1, V. Srivastava2, I. Tchernyshyov3, J. Van Eyk3, D.N. Robinson1; 1Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD, 2 Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 3Advanced Clinical Biosystems Institute, Cedar-Sinai Medical Center, Los Angeles, CA B420/P1862 Oxidation of F-actin controls the terminal steps of cell division. S. Frémont1, H. Hammich2, J. Bai1, H. Wioland3, K. Klinkert1, M. Rocancourt1, C. Kikuti2, D. Stroebel4, G. Romet-Lemonne3, O. Pylypenko2, A.M. Houdusse2, A.F. Echard1; 1Cell Biology and Infection, Institut Pasteur, Paris, France, 2Cell Biology, Institut Curie, Paris, France, 3Cell Biology, Institut Jacques Monod, Paris, France, 4IBENS, Ecole Normale Supérieure, Paris, France

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B421/P1863 Comparative analysis of the GAP activity of C. elegans CYK-4 in the germline epithelium and embryonic cytokinesis. K. Lee1, J. Rahajeng2, S.J. Field2, A.B. Desai1, R.A. Green1, K. Oegema1; 1Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, 2Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA B422/P1864 Control of actin polymerization by actin capping complex, CapZ in the terminal stages of cytokinesis. S.J. Terry1, U. Eggert1; 1Randall Division of Cell & Molecular Biophysics, King’s College London, London, United Kingdom B423/P1865 Polo kinase mediates the phosphorylation and cellular localization of Nuf/FIP3, a Rab11 effector. L.A. Brose1, J. Crest1,2, L. Tao1,3, W. Sullivan1; 1Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, 2 Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 3Biology, University of Hawai’i at Hilo, Hilo, HI

B425/P1867 Cytokinetic events are spatiotemporally organized by a gradient of active Cdc42. B.S. Hercyk1, B. Wei1, M. Das1; 1Biochemistry Cellular and Molecular Biology, University of Tennessee, Knoxville, TN B426/P1868 Spatiotemporal characterization of cytokinetic abscission in developing zebrafish embryos. S. Adar1, R. Birnbaum1, N. Elia1; 1Life Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel

Chromosome Organization in Meiosis B427/P1869 Yeast chromosomes exhibit subdiffusive motion during meiosis. T. Newman1, J. McGehee1,2, C. Cahoon1,3, . . Elnatan1,4, . . Bui1, . . Chu1, S. Burgess1; 1Molecular and Cellular Biology, University of California, Davis, Davis, CA, 2Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 3Stowers Institute of Medical Research, Kansas City, MO, 4Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA

B428/P1870 Chromosome congression and segregation in mammalian oocytes. C.M. Heath1, S.M. Wignall1; 1Molecular Biosciences, Northwestern University, Evanston, IL B429/P1871 Phosphoregulation of meiotic chromosome dynamics by CHK-2 and PLK-2. Y. Kim1,2,3, S.C. Rosenberg4,5, O. Rog1,3, N. Kostow1,3, K.D. Corbett4,5, A.F. Dernburg1,3; 1Howard Hughes Medical Institute, Chevy Chase, MD, 2Department of Biology, Johns Hopkins University, Baltimore, MD, 3Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 4Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, 5 Ludwig Institute for Cancer Research, La Jolla, CA B430/P1872 Dynamic centromeres facilitate chromosome segregation in oocytes. S.J. Radford1, A. Parikh1,2, K.S. McKim1,2; 1Waksman Institute, Rutgers University, Piscataway, NJ, 2Department of Genetics, Rutgers University, Piscataway, NJ B431/P1873 Diversity of meiotic mechanisms in the nematode lineage. B. Avsaroglu1,2, J.J. Bayes3, K.S. Baskevitch1,3, A.F. Dernburg1,2,3; 1Molecular and Cell Biology, UC Berkeley, Berkeley, CA, 2California Institute for Quantitative Biosciences, Berkeley, CA, 3Howard Hughes Medical Institute, Berkeley, CA B432/P1874 A self-extinguishing signaling circuit within the synaptonemal complex regulates meiotic recombination. A.F. Dernburg1,2,3,4, O. Rog1,3,4, S. Köhler1,3,4, L. Zhang1,3,4; 1Howard Hughes Medical Institute, Chevy Chase, MD, 2Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 3Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 4California Institute for Quantitative Biosciences (QB3), Berkeley, CA B433/P1875 Super-resolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intact C. elegans tissue. M. Wojcik1, S. Köhler2, A.F. Dernburg2, K. Xu1; 1Chemistry, UC Berkeley, Berkeley, CA, 2 Molecular and Cell Biology, UC Berkeley, Berkeley, CA B434/P1876 F-actin restricts kinesin-1 dependent sperm transport in C. elegans meiotic embryos. M.T. Panzica1, H.C. Marin1, A.J. Rocha1, F.J. McNally1; 1MCB, University of California- Davis, Davis, CA B435/P1877 Meiotic regulation of SOD1. H.M. Vander Wende1, D.W. Goodnight1, G.A. Brar1; 1Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Spindle Assembly 3 B436/P1878 Biophysics of mitotic spindle positioning in C. elegans embryos. H. Wu1,2, E. Nazockdast3, C. Yu2,4, M.J. Shelley3,5, D.J. Needleman2,4,6; 1Department of Physics, Harvard University, Cambridge, MA, 2FAS Center for Systems Biology, Harvard University, Cambridge, MA, 3 Center for Computational Biology, Simons Foundation, New York, NY, 4John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 5Courant Institute of Mathematical Sciences, New York University, New York, NY, 6Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA B437/P1879 Microtubule-associated proteins in S. cerevisiae promote microtubule formation from a fragment of the spindle pole body. B.R. King1, T. Vojnar1, K. Yabut1, E. Muller1, T.N. Davis1; 1Biochemistry, University of Washington, Seattle, WA B438/P1880 Mitotic Golgi disassembly is required for bipolar spindle formation and mitotic progression. G. Guizzunti1, J. Seemann1; 1Cell Biology, UT Southwestern, Dallas, TX B439/P1881 Phosphorylation of TPX2 C-terminus contributes to bipolar spindle assembly. B. Estes1,2, B. Mann1,2, C. Pelletier1, P. Wadsworth1; 1Biology Department, University of Massachusetts Amherst, Amherst, MA, 2Molecular and Cell Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA B440/P1882 MESP-1 collaborates with KLP-18/Kinesin-12 to promote acentrosomal spindle bipolarity in C. elegans oocytes. I.D. Wolff1, E.C. Landahl2, S.E. Rice3, S.M. Wignall1; 1Department of Molecular Biosciences, Northwestern University, Evanston, IL, 2Department of Physics, DePaul University, Chicago, IL, 3 Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL B441/P1883 RanGTP regulation of Kinesin-14 microtubule cross-linking and sliding. S.C. Ems-McClung1, L.N. Weaver2, C.E. Walczak1; 1Medical Science Program, Indiana University, Bloomington, IN, 2 Biology, Indiana University, Bloomington, IN B442/P1884 Induction of cell cycle progression and mitotic spindle assembly via light-induced release of a small number of proteins from photodegradable hydrogels. J.S. Bisht1,2, P.J. LeValley1,3,4, B.E. Noren1,3, M. Tomschik2, A.M. Kloxin4, J.S. Oakey1,3, J.C. Gatlin1,2; 1Cell Division Group, Marine Biological Laboratory, Woods Hole, MA, 2 Department of Molecular Biology, University of Wyoming, Laramie, WY, 3Department of Chemical Engineering, University of Wyoming, Laramie, WY, 4Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE

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B424/P1866 Multimodal and polymorphic interactions between anillin and actin: their implications for cytokinesis. S. Jananji1, C. Risi2, G. Laflamme3, L. Picard1, R. Van Sciver2, A. Albaghjati3, G.R. Hickson1,4, B.H. Kwok3, V.E. Galkin2; 1SainteJustine Hospital Research Center, Montreal, QC, 2Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA, 3Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, 4Pathology Cell Biology, Université de Montréal, Montreal, QC

Tuesday Poster Session

Board No./Presentation No. B443/P1885 Ensuring genome stability: a novel experimental system reveals that reduced tension directly activates the spindle assembly checkpoint independent of kinetochore detachment. K.G. Proudfoot1, M. Gupta2; 1Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 2Genetics, Development, and Cell Biology, Iowa State University, Ames, IA B444/P1886 Silencing the Spindle Assembly Checkpoint. C. Marcozzi1,2, O. Nashchekina1, J. Pines1; 1Cancer Biology, The Institute of Cancer Research, London, United Kingdom, 2Gurdon Institute, Cambridge, United Kingdom B445/P1887 Mad2-Mps1 Interaction is Sufficient to Activate the Spindle Assembly Checkpoint in Budding Yeast. S. Han1, A. Dumbre-Patil1, A.P. Joglekar1; 1Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI B446/P1888 Mechanistic Basis of Spindle Size Control and Scaling. R. Farhadifar1, G. Fabig2, M. Rockman3, T. MüllerReichert2, D. Needleman1; 1MCB/SEAS, Harvard University, Cambridge, MA, 2MTZ, Technische Universität, Dresden, Germany, 3 Biology, New York University, New York, NY B447/P1889 The mitotic function of augmin is dependent on its microtubule-associated protein subunit EDE1 in Arabidopsis thaliana. Y. Lee1, Y. Hiwatashi2,3, J. Doonan3, B. Liu1; 1Department of Plant Biology, University of California, Davis, Davis, CA, 2Agricultural and Environmental Sciences, Miyagi University, Sendai, Japan, 3 The National Plant Phenomics Centre, Aberystwyth University, Aberystwyth, United Kingdom B448/P1890 Myosin activity orients cell divisions in the Drosophila embryonic epithelium. S. Chanet1, A. Martin1; 1Biology, MIT, Cambridge, MA B449/P1891 Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics. B. Mann1,2, S. Balchand1,2, P. Wadsworth1,2; 1Biology, University of Massachusetts Amherst, Amherst, MA, 2Molecular and Cellular Biology Graduate Program, Amherst, MA B450/P1892 Aurora Kinases Control Timing of Regeneration in Stentor. A. Lin1, W.F. Marshall1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B451/P1893 Sirtuin inhibition by Tenovins disrupts microtubule dynamics and chromosome structure: potential use as antimitotic agents. M. Carmena1, O. Molina1, E.M. Peat1, C. Breunig1, I. van Leeuwen2, M. Ladds2, S. Lain2, W.C. Earnshaw1; 1Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom, 22Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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Tuesday Poster Session B452/P1894 NuMA recognizes spindle microtubule minus-ends independently of dynein and spatially targets dyneinpowered force. C.L. Hueschen1,2, S.J. Kenny3, K. Xu3, S. Dumont1,4; 1Dept. of Cell and Tissue Biology, UCSF, San Francisco, CA, 2Biomedical Sciences Graduate Program, UCSF, San Francisco, CA, 3Dept. of Chemistry, UC Berkeley, Berkeley, CA, 4Dept. of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA B453/P1895 The ‘Wait Anaphase’ Signal Is Not Spindle Confined. L.R. Heasley1, S.M. Markus1, J.G. DeLuca1; 1Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO B454/P1896 Probing the role of microtubule contact geometry in cortical force generation at mitosis. J. Guild1, S. Dumont1,2; 1Dept. of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA, 2Dept. of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA

Kinetochore Assembly and Functions 3 B455/P1897 The Ndc80 complex bridges two Dam1 complex rings. J. Kim1, A. Zelter1, N.T. Umbreit1,2, A. Bollozos1, R. Johnson3, M. MacCoss3, C.L. Asbury4, T.N. Davis1; 1Biochemistry, University of Washington, Seattle, WA, 2Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 3Genome Sciences, University of Washington, Seattle, WA, 4Physiology and Biophysics, University of Washington, Seattle, WA B456/P1898 Mechanism of Cdt1-mediated control of kinetochore microtubule attachment stabilization by the Ndc80 Complex. S. Agarwal1, S. Seshadrinathan1, J.G. Cook2, R.J. McKenney3, D. Varma1; 1Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 2Biochemistry and Biophysics, UNC Chapel Hill School of Medicine, Chapel Hill, IL, 3Molecular and Cellular Biology, University of California at Davis, Davis, CA B457/P1899 Kinesin-5 regulates Ndc80 tension at the kinetochore. A. Suzuki1, K.M. Granger1, B.L. Badger1, E.D. Salmon1, K. Bloom1; 1Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC B458/P1900 An alternative pathway independent of Ndc80 and Rod function for chromosome alignment during mitosis. M. Amin1, D. Varma1; 1Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL

B459/P1901 Kif18A coordinates the alignment and attachment of chromosomes during cell division. H. Kim1, C. Fonseca1, J.K. Stumpff1; 1Molecular Physiology and Biophysics, University of Vermont, Burlington, VT B460/P1902 A nucleoporin docks protein phosphatase 1 to direct meiotic chromosome segregation and nuclear assembly. N. Hattersley1, D.K. Cheerambathur1, M. Moyle1, M. Stefanutti2, A.K. Richardson1, K. Lee1, J. Dumont2, K. Oegema1, A.B. Desai1; 1Ludwig Cancer Research, University of California, San Diego, San Diego, CA, 2University Paris Diderot, Institut Jacques Monod, Paris, France B461/P1903 Correction of aneuploidy in meiosis in C. elegans. E. Vargas1, K. McNally1, D.B. Cortes1, F.J. McNally1; 1Molecular and Cellular Biology, University of California, Davis, Davis, CA B462/P1904 An Atypical Mechanism of Chromosome Segregation in the C. elegans Oocyte. K.A. Laband1, M. Stefanutti2, J. Dumont1; 1Institut Jacques Monod, Paris, France, 2Institut Curie, Paris, France B463/P1905 A novel chromosome segregation mechanism during female meiosis. K. McNally1, M.T. Panzica1, T. Kim2, D.B. Cortes1, F.J. McNally1; 1Molecular and Cellular Biology, University of California, Davis, Davis, CA, 2Cellular Molecular Medicine, Ludwig Institute for Cancer Research, La Jolla, CA B464/P1906 C. elegans oocytes detect meiotic errors in the absence of apparent end-on kinetochore attachments. A.C. Davis-Roca1, C.C. Muscat1, S.M. Wignall1; 1Molecular Biosciences, Northwestern University, Evanston, IL B465/P1907 End-on microtubule attachment to the kinetochore is necessary, however not sufficient, to inactivate spindle assembly checkpoint signaling. B. Roy1, A. Joglekar1, J. Sim1, V. Verma1; 1CDB, University of Michigan, Ann Arbor, MI B466/P1908 Mps1 kinase activation couples kinetochore microtubule attachment sensing to chromosome stability. Z. Dou1, X. Liu1, W. Wang1, L. Xu1, C. Fu1, X. Yao1; 1Anhui Key Laboratory for Cellular Dynamics & Chemical Biology, Hefei National Laboratory for Physical Sciences at Nanoscale, Hefei, China B467/P1909 Study of Mps1 kinase regulation through its N-Terminal region. G. Combes1, P. Thebault1, L. Murakami1, S. Elowe1; 1Reproduction, perinatal health, and child health, Centre de Recherche du CHUUniversité Laval, Quebec, QC B468/P1910 Biophysics of kinetochoremicrotubule attachment. T. Yoo1, D.J. Needleman1; 1John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B469/P1911 The mammalian kinetochore independently regulates its passive and active interfaces with microtubules. A.F. Long1, D.B. Udy1, S. Dumont1,2; 1Cell and Tissue Biology, University of California San Francisco, San Francisco, CA, 2Cell and Molecular Pharmacology, University of California San Francisco, San Francisco, CA B470/P1912 The human Ska kinetochore complex bears load on dynamic microtubules and strengthens the microtubule end attachments of weakened Ndc80 complexes. L.A. Helgeson1, C.L. Asbury2, T.N. Davis1; 1Biochemistry, University of Washington, Seattle, WA, 2Physiology Biophysics, University of Washington, Seattle, WA B471/P1913 Hec1 architecture at human kinetochores is responsive to microtubule attachment status. A.A. Kukreja1, A.P. Joglekar1,2; 1Biophysics, University Of Michigan, Ann Arbor, MI, 2Cell and Developmental Biology, University of Michigan, Ann Arbor, MI B472/P1914 Structural studies of the budding yeast kinetochore using dualcolor superresolution microscopy. K.A. Cieslinski1, J. Ries1; 1Cell Biology and Biophysics, EMBL, Heidelberg, Germany

Cancer Therapy 3

B475/P1916 The p97 inhibitor CB-5083 is a unique disrupter of protein homeostasis in cancer. Z. Wu1, S. Djakovic1, J. Rice1, B. Kumar1, S. Kiss von Soly1, A. Madriaga1, E. Valle1, F. Soriano1, M.K. Menon1, J. Wang1, B. Yao1, Y. Tang1, R. LeMoigne1, H. Zhou1, D. Wustrow1, M. Rolfe1, D.J. Anderson1; 1Cleave Biosciences, Burlingame, CA B476/P1917 Effects of Nanomaterials on HB-EGF Protein Expression in Endometrial (RL95-2), Cervical (HeLa) and Lung Cancer (A549) Cells and Photothermal Therapy. D. Gilbert1, D. Peterson1, S. Hussain2, H. Roberson2, J. Lewis2, S.C. Gonzales1, L. Carson Ph.D2, G. Regisford Ph.D2, A. Oki1; 1Chemistry, Prairie View AM University, Prairie View, TX, 2 Biology, Prairie View AM University, Prairie View, TX

B477/P1918 Photothermal Therapy in an Endometrial Cancer Cell Line, (RL952) Using Copper Sulfide and Chitosan Nanoparticles. J. Lewis1, D. Gilbert2, H. Roberson1, S.C. Gonzales2, L. Carson Ph.D3, G. Regisford Ph.D1, A. Oki2; 1Biology, Prairie View AM University, Prairie View, TX, 2Chemistry, Prairie View AM University, Prairie View, TX, 3Cooperative Agricultural Research Center, Prairie View AM University, Prairie View, TX B478/P1919 Ovarian Cancer being treated with Nanoparticles. H. Roberson1, G. regisford1, D. Gilbert1, S.C. Gonzales1, J. Lewis1; 1Biology, Prairie View,Prarie View, TX B479/P1920 HDAC inhibitor treatment induces a metastatic phenotype in cell lines with p53 gain of function mutations. M.R. Montgomery1, E.E. Hull1; 1Biomedical Sciences, Midwestern University, Glendale, AZ B480/P1921 Low-Dose Long-Term Dimethylsulfoxide (DMSO) Reduces Carcinogenity and Changes Some Morphological And Biochemical Properties of HepG2 Cells. R.G. Aktas1, M. Erinc1, H. Isan1, S. Uzun2; 1Cancer and Stem Cell Research Center, School of Medicine, Maltepe University, Istanbul, Turkey, 2 Department of Biology, Faculty of Science, Istanbul University, Istanbul, Turkey B481/P1922 Study of Toxicity of Copper Sulfide and Graphene Oxide Nanoparticles for Use in Photothermal Therapy in the Ovarian Cancer Cell Line, (SKOV-3). J.C. DuBois1, S. Gonzales1, H. Roberson1, J. Lewis1, G. Regisford Ph.D1, A. Oki1, D. Gilbert1, L. Carson Ph.D1; 1Biology, Prairie View AM University, Prairie View, TX B482/P1923 The effects of Ganoderma lucidum extract fractions in TripleNegative Breast Cancer. J.J. FelicianoIldefonso1, G. Lamela1, I.J. Suárez-Arroyo1, T. Ling2, F. Rivas2, L.A. Cubano3, M.M. Martinez-Montemayor1; 1Department of Biochemistry, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 2 Chemical Biology Therapeutics, St. Jude Children’s Research Hospital, Memphis, TN, 3 Department of Anatomy and Cell Biology, Universidad Central del Caribe-School of Medicine, Bayamon, PR

B485/P1926 The 2-O-methylmagnolol activates long non-coding RNA GAS5 and inhibits growth of skin cancer cells. C. Chen1, C. Chan1, J. Fang2, T. Wang3, T.V. Wang4; 1Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan City, Taiwan, 2Graduate Institute of Natural Products, Chang Gung University, Taoyuan City, Taiwan, 3Tissue Bank, Chang Gung Memorial Hospital, Taoyuan City, Taiwan, 4 Department of Molecular and Cellular Biology, Chang Gung University, Taoyuan City, Taiwan B486/P1927 Saffron’s Bioactive Molecule Prevents Chemical InducedLiver Cancer: A Pre-clinical Study. A. Amin1, A.A. Hamza2, S. Daoud3, K. Khazanehdari 4, A. Al Hrout1, B. Baig1, A. Chaiboonchoe5, T.E. Adrian6, N. Zaki7, K. Salehi-Ashtiani5; 1Biology, UAE University, Al-Ain, United Arab Emirates, 2National Organization of Drug Control and Research, Giza, Egypt, 3Histopathology Laboratory, Tawaam Hospital, Al-Ain, United Arab Emirates, 4Molecular Biology and Genetics Laboratory, Dubai, United Arab Emirates, 5 Center for Genomics and Systems Biology, New York University-Abu Dhabi, Abu Dhabi, United Arab Emirates, 6College of Medicine and Health Sciences, UAE University, Al-Ain, United Arab Emirates, 7College of Information Technology, UAE University, AlAin, United Arab Emirates B487/P1928 Prolonged Cytostatic Impact of a Novel Small Hydroxamic Acid: Differentiation and Normalization of Glioblastoma Multiforme In Vitro. T. Ogas1, A. Pendleton1, L. Frolova2, S. Rogelj1; 1Biology, New Mexico Institute of Mining and Technology, Socorro, NM, 2 Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM B488/P1929 Inhibition of adhesion and migration processes in melanoma cells using cyclic peptide MkA09s. P.M. Cunha1, M.M. Kanashiro2, J.H. Fernandez1; 1Laboratório de Química e Função de Proteínas e Peptídeos, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brazil, 2 Laboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brazil

B483/P1924 Neriifolin in the extracts of Cerbera manghas L. effectively inhibits the growth of glioblastoma and its cancer stem cells in vitro and in vivo. J. Tsai1, Y. Tseng1, Y. Lai1; 1Department of Life Science, National Taiwan Normal University, Taipei, Taiwan

B489/P1930 Epigenetic silencing of β-catenin by NADPH oxidase-derived reactive oxygen species facilitates migration and invasion of HT29 colon cancer cells. S. Banskota1, J. Kim1; 1College of Pharmacy, Yeungnam University, Gyeongsan, Korea, South

B484/P1925 Effect of FTY720 on TRPM7 activity, calcium signaling and Neuroblastoma cell death. L. EspanaSerrano1, I. Lange1, M. Ali1, D. Tacdol1, D.L. Koomoa1; 1Department of Pharmaceutical Sciences, DKICP, University of Hawaii at Hilo, Hilo, HI

B500/P1931 shRNA Knockdown of NFKB1 expression inhibits proliferation and promotes apoptosis of renal cell carcinoma. A. Ikegami1, L.F. Teixiera1, M.S. Braga2, E.C. da Silva1, M.H. Bellini1; 1Biotechnology Department, IPENCNEN/SP, São Paulo, São Paulo, Brasil, Brazil, 2Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, São Paulo, Brasil, Brazil

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B474/P1915 Platinum coordinated compounds bind DNA and alter cellular viability presenting the potential for use as novel anticancer therapeutics. D.S. Shah1, B.T. Dang1, J. Hu2, M.L. Mortensen2, B.W. Smucker 2, L.F. Barton1; 1Department of Biology, Austin College, Sherman, TX, 2 Department of Chemistry, Austin College, Sherman, TX

Tuesday Poster Session

Board No./Presentation No.

Tuesday Poster Session

B501/P1932 BIX02189 inhibits TGF-β1induced lung cancer cell metastasis by directly targeting TGF-β type I receptor. S. Park1, Y. CHOI1, B. Kim1; 1Biochemistry, Kangwon National University, Chuncheon, Korea, South

B510/P1941 The Effect of p85-sHER3 on Cancer Cell Growth and Migration in Melanoma derived cell line: Requirement for Tenascin-C. N.J. Maihle1; 1Georgia Cancer Center, Augusta University, Augusta, GA

B502/P1933 Kaempferol Suppresses Transforming Growth Factor-β1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Thr 179. Y. CHOI1, S. Park1, B. Kim1; 1Department of Biochemistry, Kangwon National University, Chuncheon, Korea

B511/P1942 The anticancer effects of miR-15a. C. Alderman1, A. Sehlaoui2, Y. Yang1; 1Biology, Emporia State University, Emporia, KS, 2Physical Sciences, Emporia State University, Emporia, KS

B503/P1934 NSAIDs-induced reactive oxygen species from mitochondria enhanced accumulation of photosensitizer in gastric cancer cells. H. Matsui1, H. Ito1; 1Faculty of Medicine, University of Tsukuba, Tsukuba, Japan B504/P1935 MiRNA-26a Inhibits the Proliferation and Invasiveness of Malignant Melanoma and Directly Targets on the MITF gene. H. Qian1, C. Yang1, Y. Yang1; 1Department of Biological Sciences, Emporia State University, Emporia, KS B505/P1936 Identification of novel isoformspecific HDAC inhibitors. N. Ramasamy1, H. Ravinarayanan1, K. Sundar1; 1Department of Biotechnology, Kalasalingam University, Krishnankoil, India B506/P1937 Targeting hypoxia is an essential prerequisite for cell sensitivity to metformin and lapatinib. S. Hong1,2, H. Jin3, M. Seong4, H. Kim4, W. Noh4, I. Park5; 1Department of Translational Research, Korea Institute of Radiological Medical Sciences, Seoul, Korea, South, 2 Department of Food and Microbial Technology, Seoul Women’s University, Seoul, Korea, South, 3KIRAMS Radiation Biobank, Korea Institute of Radiological Medical Sciences, Seoul, Korea, South, 4 Department of Surgery, Korea Institute of Radiological Medical Sciences, Seoul, Korea, South, 5Division of Basic Radiation Bioscience, Korea Institute of Radiological Medical Sciences, Seoul, Korea, South B507/P1938 Modulation of Cell Death and Multicellular Tumor Spheroid Growth by DCA in MCF-7 and MDA-MB-231 Breast Cancer Cells. J. Yang1, Y. Shin1, K. KANG1; 1Chemistry and Biology, Korea Science Academy of KAIST, BUSAN, Korea, South B508/P1939 Combination of Vitamin C and BRAF Inhibitor in Treatment of Human Malignant Melanoma. Y. Yan1, Y. Xiao1, G. Yang1, Y. Yang1; 1Biological Science, Emporia State University, Emporia, KS B509/P1940 Inhibition of PANX1 reduces the malignant properties of human melanoma. T. Freeman1, L. Harland1, D. Johnston1, D. Nouri Nejad1, B. O’Donnell1, S. Penuela1; 1Anatomy and Cell Biology, The University of Western Ontario, London, ON

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B512/P1943 Targeted cytochrome c delivery to cancer cells using the transferrinreceptor. M. Saxena1, Y. Delgado2, R. Sharma1, S. Sharma1, S.P. Guzman2, A.D. Tinoco2, K.H. Griebenow2; 1Environmental Sciences, University of Puerto Rico Rio Piedras Campus, San Juan, PR, 2Chemistry, University of Puerto Rico Rio Piedras Campus, San Juan, PR B513/P1944 Mapping p63 phosphorylation after DNA damage. K. Jung1, E. Suh1; 1Life Science, Ewha Woman’s University, Seoul, Korea, South B514/P1945 Effects of UTX inhibition on neuronal differentiation through REST. Y. Santana Rivera1, J. Swaminathan2, V. Gopalakrishnan2, B.A. Kennis2; 1Cancer Comprehensive Center, University of Puerto Rico, San Juan, PR, 2Pediatric Research, MD Anderson Cancer Center, Houston, TX

Cancer Stem Cells B515/P1946 iPSC derived CSC model with lung metastasis developed in the microenvironment of lung carcinoma. A.K. Oo1, T. Kasai1, A. Vaidyanath1, H.B. Mahmud 1, N. Nair1, A.S. Calle1, M. Seno1; 1Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan B516/P1947 ITGA1 is a novel biomarker and therapeutic target for blocking stemness in pancreatic cancer. S. Kim1, A. Gharibi1, D.C. Brambilla1, Y. Adamian1, M. Hoover1, J. Lin1, M. Agajanian1, L. Wolfenden1, J.A. Kelber1; 1Biology, California State University Northridge, Northridge, CA B517/P1948 Promising Association of Expression of CD133 and SOX2 with Distant Metastatic Relapse and Tumor Growth in Advanced Prostate Cancer. D. Srinivasan1, S. Majumdar1, L.T. Senbanjo1, M.A. Chellaiah1; 1Department of Oncology and Diagnostic Sciences, University of Maryland, Dental School, Baltimore, MD

B518/P1949 Ganoderma lucidum extract significantly decreases stemness properties in Inflammatory Breast Cancer cells via STAT3 regulation. T.J. Rios1, Y. Loperena1, M.Y. Lacourt1, P. Lopez2, Y. Yamamura2, L.A. Cubano3, M.M. MartinezMontemayor1; 1Department of Biochemistry, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 2Department of Basic Sciences (Microbiology), Ponce Health Sciences University, Ponce, PR, 3 Department of Anatomy and Cell Biology, Universidad Central del Caribe-School of Medicine, Bayamon, PR B519/P1950 Matrix Metalloproteinases-9 and 10 are required for prostate cancer stem cell maintenance, tumor initiation and metastasis. V. Joga1, S. Rentala2, A. Mokkapati2; 1Dept. of Biotechnology, Institute of Science, GITAM University, Visakhapatnam, India, 2Dept of Biotechnology, Institute of Technology GITAM University, Visakhapatnam, India B520/P1951 Constitutive activation of RhoA sensitizes glioblastoma-initiating cells to mechanical inputs, reduces invasion and downregulates epidermal growth factor signaling. J.H. Hughes1,2, S.Y. Wong1,2, T.A. Ulrich1,2, L.P. Deleyrolle3, J.L. MacKay4, G. Lin1,2, R.T. Martuscello3, M.A. Jundi3, B.A. Reynolds3,5, S. Kumar1,2; 1UC Berkeley - UCSF Graduate Program in Bioengineering, Berkeley, CA, 2Department of Bioengineering, University of California, Berkeley, Berkeley, CA, 3Department of Neurosurgery, University of Florida, Gainesville, FL, 4Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA, 5 Queensland Brain Institute, University of Queensland, St. Lucia, Australia B521/P1952 Aberrant activation of CaMKII-gamma accelerates chronic myeloid leukemia blast crisis. Y. Gu1, W. Huang1; 1Department of Cellular & Mol. Diabetes, Beckman Research Institute, City of Hope Medical Center, Duarte, CA B522/P1953 Superoxide dismutase protects osteoprogenitors from irradiation with low-LET but not high-LET species. A. Schreurs1, L. Tran1, C.G. Tahimic1, J.S. Alwood1, R.K. Globus1; 1Space Biosciences, NASA ARC, Mountain View, CA B523/P1954 Optimal 3D cell culture model of human renal carcinoma stem-like cells. A.M. Czarnecka1, Z.F. Bielecka1,2, K.K. Brodaczewska1, K. Maliszewska1,3, A. Malinowska4, P. Krasowski1,5, D. Matak1,2, M. Lipiec1,6, J. Piwowarski5, E. Grzesiuk5, C. Szczylik1; 1Department of Oncology with Laboratory of Molecular Oncology, Military Institute of Medicine, Warsaw, Poland, 2 School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland, 3 Institute of Biochemistry and Biophysics, Laboratory of DNA Sequencing and Oligonucleotides Synthesis, Polish Academy of Sciences, Warsaw, Poland, 4Institute of

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. Biochemistry and Biophysics, Environmental Laboratory of Mass Spectrometry, Polish Academy of Sciences, Warsaw, Poland, 5 Institute of Biochemistry and Biophysics, Department of Molecular Biology, Polish Academy of Sciences, Warsaw, Poland, 6 Faculty of Pharmacy with Laboratory Medicine Division, Medical University of Warsaw, Warsaw, Poland B524/P1955 Reluctant Opening of Mitochondrial Permeability Transition Pore Sensitizes Glioma Stem Cells to a Novel OXPHOS Inhibitor. Y. Shi1, K.S. Lim2, Q. Liang2, Y. Li1, I. Nazarenko1, H. Wang2, N. Williams2, J.D. Brabander2, L.F. Parada1; 1Cancer Biology Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, 2Developmental Biology, UT Southwestern Medical Center, Dallas, TX B525/P1956 Cancer Stem Cell Proliferation in Human Prostate Cancer Cells utilizing a New Defined 3D Sphere Culture System. K. Saito1, N.J. Asbrock1, V. Chu1; 1Cellular Assays, Biological Reagents & Kits, MilliporeSigma, Temecula, CA

Oncogenes and Tumor Suppressors 3 B526/P1957 The Oncogene MYC Alters Mitotic Function via TPX2. J. Rohrberg1, A. Corella1, S. Balakrishnan1, A. Goga1; 1Cell and Tissue Biology, UCSF, San Francisco, CA

B528/P1959 Overexpression of Early Mitotic Inhibitor 1 (Emi1) promotes genomic instability and cancer. S. Vaidyanathan1, K. Cato1, L. Tang2, S. Pavey1, N.K. Haass1, B.G. Gabrielli1, P.H. G. Duijf1; 1The University of Queensland Diamantina Institute, Brisbane, Australia, 2 School of Basic Medical Sciences, Fudan University, Shanghai, China B529/P1960 Chk1-mediated phosphorylation of Cdh1 promotes its SCFβTrCP-dependent degradation to facilitate cell cycle progression and checkpoint regulation. D. Pal1, A. Messina1, M.K. Summers1; 1Radiation Oncology, The Ohio State University Comprehensive Cancer Center- The James Cancer Hospital, Columbus, OH

B531/P1962 BCL2 methylation in Oral Squamous Cell Carcinoma. G. Khor1, G. . Froemming2, R. Binti Zain3; 1Faculty of Dentistry, University Teknologi MARA, Selangor, Malaysia, 2Faculty of Medicine, University Teknologi MARA, Selangor, Malaysia, 3Oral Cancer Research and Coordinating Center, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia B532/P1963 Inactivation of Ezh2 upregulates Gfi1 to accelerate aggressive Myc-driven Group 3 medulloblastoma. B.T. Vo1, C. Li1, M. Morgan2, I. Theurillat3, D. Finkelstein4, S. Wright1,5, J. Hyle1,5, S.M. Smith1, Y. Fan4, Y. Wang4, G. Wu4, B.A. Orr6, P.A. Northcott7, A. Shilatifard2, C.J. Sherr1,5, M.F. Roussel1; 1Deparment of Tumor Cell Biology, St. Jude Children’s Research Hospital, Memphis, TN, 2Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Department of Cell Biology and Infection, Institut Pasteur, Paris, France, 4Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, TN, 5Howard Hughes Medical Institute, Memphis, TN, 6Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN, 7Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, TN B533/P1964 Semaphorin 3B is a Direct Target of GATA3 Transcription Factor and is Indispensible for GATA3 Tumor Suppressive Activity in the Mammary Gland. C. Wang1,2,3, P. Shahi2,4, J. Chou2, H. Gonzalez2, M. Lai1,3, Z. Werb2; 1The Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan, 2 Department of Anatomy, University of California, San Francisco , San Francisco, CA, 3Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan, 4Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA B534/P1965 The X-linked tumor suppressor TSPX activates CDKN1A/p21 gene and suppresses MYC expression and cell proliferation in prostate cancer. T. Kido1, Y. Li1, Y.C. Lau1; 1Department of Medicine, VA Medical Center, University of California, San Francisco, San Francisco, CA

B536/P1967 MiR-133a function in the pathogenesis of dedifferentiated liposarcoma. P.Y. Yu1, J.M. Fenger2, A. Strohecker1, O.H. Iwenofu3, R.E. Pollock4, D.C. Guttridge1; 1Cancer Biology and Genetics, Ohio State University, Columbus, OH, 2Veterinary Clinical Sciences, Ohio State University, Columbus, OH, 3Pathology, Ohio State University, Columbus, OH, 4 Surgical Oncology, Ohio State University, Columbus, OH B537/P1968 Modeling Glioma-Associated Genomic Rearrangements Using Somatic Genome Editing. P.J. Cook1, A. Ventura1, R. Benezra1; 1Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY B538/P1969 The RNA-Binding Protein with Multiple Splicing (RBPMS) Acts as a Tumor Suppressor in Ovarian Cancer. P.E. Vivas-Mejia1, P. BaezVega2, G. Santiago1, F. Valiyeva2, N.J. Maihle1; 1Biochemistry, University of Puerto Rico Medical Sciences Campus, San Juan, PR, 2University of Puerto Rico Cancer Center, San Juan, PR

Regulators of Invasion and Metastasis B539/P1970 Cell Cycle Regulation of Invasive Behavior. A.Q. Kohrman1, W. Zhang1, D.Q. Matus1; 1Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY B540/P1971 Identification of new regulators of tumor cells clustering. V. Lobjois1, B. Ducommun1; 1ITAV- CNRS, University of Toulouse, Toulouse, France B541/P1972 CD44-intracellular domain (ICD) a possible co-factor for Runx2 in the regulation of transcription of metastasis related genes. L.T. Senbanjo1, D. Srinivasan1, S. Majumdar1, M.A. Chellaiah1; 1Department of Oncology and Diagnostic Sciences, University of Maryland Baltimore, Baltimore, MD B542/P1973 Role of oriented cell divisions in luminal breast cancer initiation. L. Seldin1, I.G. Macara1; 1Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN

B535/P1966 CD44-Associated Response to Hydrogen Peroxide-Mediated Oxidative Stress in MCF-7 Cells. A.S. Shelton1, J.P. Parson1, K.E. Miletti-Gonzalez1; 1Biological Sciences, Delaware State University, Dover, DE

B530/P1961 DNA methylation, DNMT1 and breast cancer cells. L. DelgadoCruzata1, L. Duran1, R.M. Santella2, M.B. Terry2; 1Sciences, John Jay College, City University of New York, New York, NY, 2Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY

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B527/P1958 Understanding the multinucleation induced by the inhibition of Aurora Kinase A in precancerous skin cells. E. Torchia1, W. Ryan1, J. Fernandez1, M. Peterson1; 1Dermatology, University of Colorado Anschutz Medical Campus, Aurora, CO

Tuesday Poster Session

Board No./Presentation No. B543/P1974 SILAC identification of cell adhesion plasma membrane associated proteins in inflammatory breast cancer models. I.J. Suárez-Arroyo1, Y.R. FelizMosquea2, J. Perez-Laspiur3, R. Arju4, S. Giashuddin5, G. Maldonado6, R.J. Schneider4, L.A. Cubano7, M.M. MartinezMontemayor1; 1Department of Biochemistry, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 2Department of Biology, Inter American University, Bayamon, PR, 3Translational Proteomics, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, 4Radiation Oncology, New York University, New York, NY, 5Department of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, 6 Data Management and Statistical Research Support Unit, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 7 Department of Anatomy and Cell Biology, Universidad Central del Caribe-School of Medicine, Bayamon, PR B544/P1975 Identification of novel molecular markers of inflammatory breast cancer. I.J. Suárez-Arroyo1, Y.R. Feliz-Mosquea2, J. Perez-Laspiur3, R. Arju4, S. Giashuddin5, G. Maldonado6, R.J. Schneider4, M.M. Martinez-Montemayor1, L.A. Cubano7; 1Department of Biochemistry, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 2Department of Biology, Inter American University, Bayamon, PR, 3Translational Proteomics, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, 4Radiation Oncology, New York University, New York, NY, 5Department of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, 6 Data Management and Statistical Research Support Unit, Universidad Central del Caribe-School of Medicine, Bayamon, PR, 7 Department of Anatomy and Cell Biology, Universidad Central del Caribe-School of Medicine, Bayamon, PR B545/P1976 Down-regulation of a high molecular weight tropomyosin Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells. S. Jeong1, S. Lim1, G. Schevzov2, P.W. Gunning2, D.M. Helfman1; 1Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea, South, 2Oncology Research Unit, School of Medical Sciences, Sydney, Australia B546/P1977 Establishing the involvement of exosomal NM23 in pro-angiogenic communication between triple negative breast cancer cells and their vascular targets. S. Duan1, S. Nordmeier1, I.L. Buxton1; 1Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV B547/P1978 The role of ELK3 to regulate transforming growth factor-β signaling in the triple negative breast cancer. J. Park1, K. Park1, J. Park1; 1Biomedical Science, Cha University, Seong Nam, Korea, South

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Tuesday Poster Session B548/P1979 Assembly of the WASH complex by HSBP1 promotes mammary carcinoma invasiveness. S.P. Visweshwaran1, P.A. Thomason2, R. Guérois3, S. Vacher4, S. Lilla2, C. LazennecSchurdevin1, G. Lakisic1, Y. Mechulam1, E. Schmitt1, I. Bièche4, R.H. Insall2, A. Gautreau1; 1CNRS UMR7654, Ecole Polytechnique - Université Paris-Saclay, Palaiseau, France, 2Beatson Institute, Cancer Research UK, Glasgow, United Kingdom, 3I2BC, CEA - Université ParisSaclay, Gif-sur-Yvette, France, 4Unité de Pharmacogénomique, Institut Curie, Paris, France B549/P1980 Adipose signaling and actomyosin contractility in breast cancer invasion. A.R. Acheva1, V. Deckwirth1, S. Tojkander1; 1Department of Veterinary Biosciences, Section of Pathology, University of Helsinki, Helsinki, Finland B550/P1981 The role of fad104, a positive regulator for adipogenesis, in TGFβ1-induced epithelial to mesenchymal transition. M. Goto1, M. Nishizuka1, S. Osada1, M. Imagawa1; 1Molecular Biology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan B551/P1982 PSPC1 is an activator to drive the epithelial–mesenchymal transition, stemness and TGF-β metastatic switch. Y. Jou1,2, H. Yeh1,2, Y. Lang1; 1Academia Sinica, Institute of Biomedical Sciences, Taipei, Taiwan, 2National Defense Medical Center, Graduate Institute of Life Sciences, Taipei, Taiwan B552/P1983 Arrestin 3 Mediates a Mesenchymal to Epithelial Transition in Renal Cell Carcinoma Cells. J. Masannat1, M. Russin1, Y. Daaka1; 1Anatomy and Cell Biology, University of Florida, Gainesville, FL B553/P1984 Akt-elicited phosphorylation of Acapin promotes liver cancer metastasis. J. Zhou1, X. Liu1,2, Y. Zhang1,2, W.W. Yao2, S. Zhou1, F. Wang1,2, X. Yao1,2; 1CAS Center of Excellence, University of Science and Technology of China, Hefei, China, 2Atlanta Clinical Translational Science Institute, Atlanta, GA B554/P1985 Adenosine Generated by Ectonucleotidases of GlioblastomaInitiating Cells Controls the cell migration/invasion of Glioma cells through the activation of Low-Affinity Adenosine Receptors under Hypoxia. A.S. Torres1, J.I. Erices1, I.P. Ehrenfeld2, T. Virolle3, L. Turchi3, C.F. Oyarzún1, R.E. San Martín1, C.A. Quezada1; 1Institute of Biochemistry and Microbiology, Universidad Austral de Chile, Valdivia, Chile, 2Institute of Physiology and Pathology, Universidad Austral de Chile, Valdivia, Chile, 3Institut de Biologie Valrose (iBV), Université Nice Sophia Antipolis, Nice, France

Chromatin and Chromosome Organization B556/P1986 The p150N domain of Chromatin Assembly Factor-1 regulates chromosome organization throughout the cell cycle via Ki-67. T.D. Matheson1, P.D. Kaufman1; 1Molecular, Cell and Cancer Biology, U. Massachusetts Medical School, Worcester, MA B557/P1987 The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic. J.M. Swenson1, S.U. Colmenares1, A.R. Strom1,2, S.V. Costes1, G.H. Karpen1,2; 1Organismal Systems Bioresilience, Lawrence Berkeley National Lab, Berkeley, CA, 2Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA B558/P1988 Boundaries of newly established heterochromatin domains are defined by a G-quadruplex binding protein, Lia3, and related DNA-binding proteins. D.L. Chalker1, C.M. Carle1, V.N. Jaspan1, M. Taye1, J.J. Chung1; 1Biology, Washington University in St Louis, St Louis, MO B559/P1989 CRISPR-based tracking of interphase chromosome dynamics in living cells. H. Ma1, L. Tu2, A. Naseri3, M. Huisman2, S. Zhang3, D. Grunwald2, T. Pederson1; 1Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 2RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 3Computer Science, University of Central Florida, Orlando, FL B560/P1990 Live cell imaging reveals dynamic sister chromatid linkage at individual genomic loci. R. Stanyte1, J. Nuebler2, R. Stocsits3, A. Schleiffer3, L. Mirny2, J. Peters3, D.W. Gerlich1; 1Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria, 2Institute for Medical Engineering and Sciences, and Department of Physics, Massachusetts Institute of Technology (MIT), Cambridge, MA, 3Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria B561/P1991 Spatial organization of topologically associated domains in individual chromosomes. S. Wang1,2, J. Su1,3, B.J. Beliveau4, B. Bintu1,5, J.R. Moffitt1,2, C. Wu4, X. Zhuang1,2,5; 1Howard Hughes Medical Institute, Cambridge, MA, 2 Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 3Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 4 Department of Genetics, Harvard Medical School, Cambridge, MA, 5Department of Physics, Harvard University, Cambridge, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B562/P1992 Multicolor labeling and imaging nuclear organization of native chromatin loci with type II CRISPR/Cas9 system in living cells. P. Qin1, M. Parlak2, J. Bandaria1, A. Yildiz1, A. Mazhar2; 1QB3, UC Berkeley, Berkeley, CA, 2Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA B563/P1993 Multicolor labeling of genomic loci using orthogonal CRISPR effectors and modified guide RNAs in living human cells. S. Wang1,2, J. Su1,2,3, F. Zhang4,5,6, X. Zhuang1,2,7; 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 2Department of Physics, Harvard University, Cambridge, MA, 3Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 4McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, 5Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA, 6Broad Institute of MIT and Harvard, Cambridge, MA, 7Howard Hughes Medical Institute, Chevy Chase, MD B564/P1994 Hunchback and Krüppel mediate early cell fate competence correlated with distinct actin-dependent intranuclear re-localization of gene loci in Drosophila neuroblasts. P. Chikte1, S. Jansen1, N. Dinges2, J. Urban1; 1Biology, Institute of Genetics, Mainz, Germany, Mainz, Germany, 2Institute of Molecular Biology, Mainz, Germany

B566/P1996 Nucleosome–nucleosome interactions via histone tails and linker DNA regulate nuclear rigidity. Y. Shimamoto1,2,3, S. Tamura4, K. Maeshima1,4; 1Department of Genetics, SOKENDAI University, Shizuoka, Japan, 2 AMED-PRIME, Japan Agency for Medical Research and Development, Tokyo, Japan, 3 Center for Frontier Research, National Institute of Genetics, Shizuoka, Japan, 4 Structural Biology Center, National Institute of Genetics, Shizuoka, Japan B567/P1997 Tissue mechanics regulate heterochromatin formation in breast epithelial cells. J. Northcott1, R. Bainer1, V.M. Weaver1; 1Department of Surgery, University of California San Francisco, San Francisco, CA

B569/P1999 Exploiting Non-canonical Heterochromatin-mediated Telomere Protection Mechanisms in Human Cells. T.T. Chow1, S. Chen1, J. Wei1, C. Wilson2, M.R. Arkin2, E.H. Blackburn1; 1Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, 2 Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA B570/P2000 Characterization of PARP-1 and PARP-2 function at heterochromatin domains. D. Quenet1; 1Biochemistry, University of Vermont, Burlington, VT B571/P2001 A single double strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin. A. Janssen1, G.A. Breuer2, E.K. Brinkman3, A.I. van der Meulen1, S.V. Borden1, B. van Steensel3, R.S. Bindra2, J.R. LaRocque4, G.H. Karpen1; 1Biological Systems and Engineering, Lawrence Berkeley National Lab, Berkeley, CA, 2 Departments of Therapeutic Radiology and Experimental Pathology, Yale School of Medicine, New Haven, CT, 3Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, Netherlands, 4Department of Human Science, Georgetown University Medical Center, Washington DC, DC B900/P2002 Identification of molecular determinants of Tousled-like kinase 2 (TLK2) activity. C. Jauset1,2, S. SeguraBayona2, T.H. Stracker2; 1Faculty of Medicine, Universitat de Lleida (UdL), Lleida, Spain, 2Oncology, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain B901/P2003 RecBCD degradation controls template choice during double stranded break repair. J. Wiktor1, M. van der Does1, L. Buller1, D. Sherratt2, C. Dekker1; 1Department of Bionanoscience, TU Delft, Delft, Netherlands, 2Department of Biochemistry, University of Oxford, Oxford, United Kingdom B902/P2004 Transition of Higher-Order Structure of DNA with Polyamines Causes Marked Change on GeneExpression. A. Kanemura1, Y. Yoshikawa1, W. Fukuda2, K. Tsumoto3, T. Kenmotsu1, K. Yoshikawa1; 1Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Kyoto, Japan, 2Department of Biotechnology, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan, 3 Department of Chemistry for Materials, Faculty of Engineering, Mie University, Tsu, Mie, Japan

B568/P1998 Characterization of double strand DNA breaks response in primary cells from Huntington’s disease transgenic minipig model. M. Vaskovicova1, J. Valasek1, P. Rausova1, A. Herbert2, J. Motlik1, P. Solc1; 1Pigmod Centre, Institute of Animal Physiology and Genetics, The Czech Academy of Sciences, Libechov, Czech Republic, 2Genome Damage and Stability Centre, University of Sussex, Sussex, United Kingdom

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B903/P2005 DNA Replication Timing During Development Anticipates Transcriptional Programs and Parallels Enhancer Activation. J.C. Siefert1,2, C. Georgescu3, J.D. Wren3,4, A. Koren5, C.L. Sansam1,2; 1Cell Cycle Cancer Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2 Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 5Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY B904/P2006 CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx. V.M. Morozov1, S. Giovinazzi1,2, A.M. Ishov1; 1Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 2Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL

Epigenetics and Chromatin Remodeling B905/P2007 Linker Histone function of Yeast HMO1 – Implications for DNA Repair. A. Panday1, A. . Grove1; 1Biological Sciences, Louisiana State University, Baton rouge, LA B906/P2008 Studying combinatorial histone modifications. L. Handoko1, J. Chang1, B. Kaczkowski1, K. Fujita2, M. Lizio1, Y. Sato3, M. Wakamori4, H. Kimura3, Y. Taniguchi2, T. Yanagida2, T. Umehara4, A. Minoda1; 1CLST-DGT, RIKEN, Yokohama, Japan, 2Quantitative Biology Center, RIKEN, Osaka, Japan, 3Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan, 4CLST-DSSB, RIKEN, Yokohama, Japan B907/P2009 Methylation profiles of the genes involved in self-defense mechanisms in a carnivorous plant Drosera adelae. N. Arai1, T. Ohyama1; 1Biology, Waseda University, Tokyo, Japan B908/P2010 Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation. I. Akan1, D. Love1, J.A. Hanover1; 1LCMB, NIH / NIDDK, Bethesda, MD B909/P2011 Identification and characterization of active enhancers as potential biomarkers of aggressive colorectal cancer. R. Wu1, C.R. Jerde1, R.B. Diasio1, S.M. Offer1; 1Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN

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B565/P1995 Assembly of Heterochromatin and CENP-A chromatin at Fission Yeast Centromeres. A.L. Pidoux1, P. Tong1, R. Ard1, M. Shukla1, N. Toda1, H. Berger1, R. Allshire1; 1Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, The University of Edinburgh,, Edinburgh, United Kingdom

Tuesday Poster Session

Board No./Presentation No. B910/P2012 Methylation and Acetylation of Sperm Histone 3 Regulate Chromatin Dynamics and Male Fertility. A.M. Chiappetta1,2,3, N.A. Kutchy1, E. Menezes1, A. Moura4, A. Kaya5, A. Perkins2, E. Memili1; 1Department of Animal and Dairy Sciences, Mississippi State University, Mississippi State, MS, 2Department of Computer Science and Engineering, Mississippi State University, Mississippi State, MS, 3Department of Biology and Biochemistry, University of Northwestern - St. Paul, St. Paul, MN, 4Department of Animal Science, Federal University of Ceara, Fortaleza, Brazil, 5Department of Reproduction and Artificial Insemination, Selcuk University, Konya, Turkey B911/P2013 Ccp1 homodimer mediates chromatin integrity by antagonizing CENP-A loading. Q. Dong1, F. Yin2, Y. Li2, J. Yang1, Y. Chen2, F. Li1; 1Department of Biology, New York University, New York, NY, 2 Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China B912/P2014 Mechanisms of γ-H2AX spreading by Mec1ATR and Tel1ATM around a double strand break in Saccharomyces cerevisiae. K. Li1, G. Bronk1, J. Kondev1, J.E. Haber2; 1Department of Physics, Brandeis University, Waltham, MA, 2 Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA B913/P2015 RNA dependent stabilization of SUV39H1 at constitutive heterochromatin. W.L. Johnson1, W.T. Yewdell1, S.M. McNulty2, Z. Duda3, R.J. O’Neill3, B.A. Sullivan2, A.F. Straight1; 1Biochemistry, Stanford Medical School, Stanford, CA, 2Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, 3Molecular and Cellular Biology, University of Connecticut, Storrs, CT B914/P2016 Live-cell imaging reveals dynamics and distribution of Tet1 in mouse embryonic stem cells. J. Ryan1,2, C.B. Mulholland1, E. Schmidtmann1, H. Leonhardt1; 1Biology, LMU Munich, Munich, Germany, 2Life Sciences, International MaxPlanck Research School, Munich, Germany B915/P2017 Internal modifications in the CENP-A nucleosome modulate centromeric dynamics. S. Roque1, M. Bui1, M. Pitman2, A. Nuccio3, P.G. Donlin-Asp4, A. Nita-Lazar3, G. Papoian2, Y. Dalal1; 1CCR, NCI, Bethesda, MD, 2UMCP, University of Maryland, College park, College Park, MD, 3 Laboratory of Systems Biology, NIAID, Bethesda, MD, 4Department of Cell Biology, Emory University, Atlanta, GA B916/P2018 Histone H1 phosphorylation dynamics in cell differentiation: differential regulation and function. R. Liao1, C.A. Mizzen1,2; 1Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 2 Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL

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Tuesday Poster Session

Nuclear Lamina and Laminopathies B918/P2019 Stiffness-dependent maintenance of Mkl1/SRF-signaling requires Emerin and Lamin A. M.K. Willer1, C.W. Carroll1; 1Dept. of Cell Biology, Yale University, New Haven, CT B919/P2020 Cytoskeleton medicated nuclear mechanics. D. Kim1, J. Park1, S. Sun2, D. Wirtz3; 1KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Korea, South, 2 Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 3Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD B920/P2021 Rescue of emerin-null myogenic progenitor differentiation by inhibition of multiple MAP kinases or activation of HDAC3. J.A. Ellis1, C.M. Collins1, J.M. Holaska1; 1Pharmaceutical Sciences, University of the Sciences, Philadelphia, PA B921/P2022 Emerin induces nuclear rupture in Xenopus egg extract. M.R. Dilsaver1, D.L. Levy1; 1Molecular Biology, University of Wyoming, Laramie, WY B922/P2023 Characterization of the interaction between β-Dystroglycan and emerin and its functional relevance. W.L. Gómez Monsiváis1, P.M. Azuara1, B. Cisneros-Vega1; 1Genetics and Molecular Biology, CINVESTAV-IPN, Mexico city, Mexico B923/P2024 Direct visualization of nuclear envelope breakdown. N. Wesolowska1, M. Mori2, P. Machado3, P. Lénárt1; 1Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany, 2 Department of Experimental Genome Research, Osaka University, Osaka, Japan, 3Electron Microscopy Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany B924/P2025 HECW2 ubiquitin ligase targets PCNA and Lamin B1 in laminopathic cells. V. Krishnamoorthy1, V.K. Parnaik1; 1CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India B925/P2026 RNF123 ubiquitin ligase targets lamin-binding proteins in laminopathic cells. R. Khanna1, V.K. Parnaik1; 1CSIRCentre for Cellular and Molecular Biology, Hyderabad, India B926/P2027 Lamin A-binding membranetethered kinase phosphorylates barrierto-autointegration factor. B. KC1, D.I. Kim1, K.J. Roux1; 1Children’s Health Research Center, Sanford Research, Sioux Falls, SD B927/P2028 Highly branched nuclei in the Xenopus tail fin. A.E. Wills1, H.E. Arbach1; 1Biochemistry, University of Washington, Seattle, WA

Nucleocytoplasmic Transport B928/P2029 Super-resolution study of nuclear envelope transmembrane protein transport in live cells. K.C. Mudumbi1, E. Schirmer2, W. Yang1; 1Department of Biology, Temple University, Philadelphia, PA, 2Wellcome Trust Center for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom B929/P2030 Regulation of pronuclear size in mouse zygotes. M. Ohsugi1, H. Watanabe1,2; 1Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan, 2 Department of Pathology, Immunology and Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan B930/P2031 The exportin Xpo4 recognizes eIF5A through its unique amino acid hypusine for nuclear export. M. Aksu1, S. Trakhanov1, D. Görlich1; 1Department of Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany B931/P2032 Characterizing the minimal system for mRNA quality control at the entry of the nuclear pore complex. M. Soheilypour1, M. Mofrad1; 1Department of Bioengineering, University of California, Berkeley, Berkeley, CA B932/P2033 Like Charge Regions (LCRs) are major regulators of transport through the Nuclear Pore Complex. M. Peyro1,2, M. Soheilypour1, A. Ghavami1, M. Mofrad1,2; 1Department of Bioengineering, University of California Berkeley, Berkeley, CA, 2Department of Mechanical Engineering, University of California Berkeley, Berkeley, CA B933/P2034 The interaction between the nuclear basket protein Mlp1 and the RNA-binding protein Nab2 sheds light on mRNA quality control mechanism. M. Soheilypour1, M. Peyro1,2, H. Shams1, M. Mofrad1,2; 1Department of Bioengineering, University of California, Berkeley, Berkeley, CA, 2Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA B934/P2035 Relationship of proteostasis and nucleocytoplasmic transport in neurodegenerative diseases. K. Zhang1, K. Cunningham1, K. Ruan1, J. Grima1, G. Daigle1, J. Rothstein1, T.E. Lloyd1; 1Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD B935/P2036 Altering nuclear size in melanoma cell lines affects cancer cell characteristics. L.D. Vukovic1, B.A. Stohr2, D.L. Levy1; 1Molecular Biology, University of Wyoming, Laramie, WY, 2Pathology, University of California, San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Tuesday Poster Session

B936/P2037 Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex. A. Vovk1, C. Gu1, M. Opferman2, L.E. Kapinos3, R.Y. Lim3, R. Coalson2, D. Jasnow2, A. Zilman1; 1Physics and Institute for Biomaterials and Bioengineering, University of Toronto, Toronto, ON, 2Physics and Astronomy, University of Pittsburgh, Pittsburgh, PA, 3 Biozentrum, University of Basel, Basel, Switzerland

B945/P2046 Pressurized transport of viral genome across the nuclear pore complex. R. Moussavi-Baygi1, M. Mofrad1; 1Applied Science and Technology, University of California, Berkeley, Berkeley, CA

B937/P2038 Possible Interaction of NIL-16, a Neural-Specific Cytokine Precursor, with HDAC3 and Dysbindin-1. K.W. Baugh1, S.D. Fenster1; 1Biology, Fort Lewis College, Durango, CO

B947/P2048 Nuclear volume control in the green lineage: testing the constancy of the N/C ratio in Chlamydomonas. D. Liu1,2, J.G. Umen1; 1Donald Danforth Plant Science Center, St. Louis, MO, 2Biology, University of Missouri, St. Louis, MO

B938/P2039 Unusual NLS and NES are the basis for active nucleocytoplasmic shuttling of TAZ. M.M. Kofler1, P. Speight1, K. Szaszi1,2, A. Kapus1,2; 1Keenan Research Centre, St. Michael’s Hospital, Toronto, ON, 2 Dept. Surgery and Biochemistry, University of Toronto, Toronto, ON B939/P2040 Nuclear export pathway of alpha-dystrobrevin 1. I.A. MandujanoRamos1, J. Gomez-Lopez1, B. CisnerosVega1; 1Genetics and Molecular Biology, CINVESTAV, Mexico City, Mexico

B941/P2042 Proteosome-mediated Nuclear Degradation of Alpha Dystrobrevin-1. J. Gomez-Lopez1, B. Cisneros-Vega1; 1Genetic and Molecular Biology, CINVESTAV, México City, Mexico B942/P2043 Nuclear matrix protein CIZ1 is localised to the inactive X chromosome, and its absence results in loss of Xist localisation and highly penetrant femalespecific lympho-proliferative disorder in mice. E.R. Stewart1, T. Nesterova2, R. Ridings Figueroa1, H. Coker2, J. Roulson3, A. Haslam1, G. Albadrani4, N. Brockdorff2, J.F. Ainscough1,4, D. Coverley1; 1Department of Biology, University of York, York, United Kingdom, 2Department of Biochemistry, University of Oxford, Oxford, United Kingdom, 3Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 4LICAMM, University of Leeds, Leeds, United Kingdom B943/P2044 Does the nuclear pore complex adopt different transport mechanisms in different species? R. Moussavi-Baygi1, M. Mofrad1; 1Applied Science and Technology, University of California, Berkeley, Berkeley, CA

B948/P2049 The unexpected importance of nucleoporin Nup153 in the intracellular traffic of influenza A virus. M. Acevedo1, W. Wu1, N. Pante1; 1Zoology, University of British Columbia, Vancouver, BC B949/P2050 Plasticity of nucleoporin nuclear transport receptor interactions. I. Valle Aramburu1, P.S. Tan1, S. Tyagi1, E. Lemke1; 1Structural and Computational Biology Unit, Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany B950/P2051 An alternative nuclear export pathway in Saccharomyces cerevisiae. B. Ding1, A.M. Mirza2, V. Budnik1, M. Munson2; 1Neurobiology, University of Massachusetts Medical School, Worcester, MA, 2Biochemistry Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA

Vesicle Docking and Fusion B952/P2052 MAP1B-LC1 regulates autophagosome formation by interacting with the autophagy-related SNARE syntaxin 17. K. Arasaki1, M. Tagaya1, N. Dohmae2, Y. Kurosawa1, H. Nagashima1; 1School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan, 2Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Saitama, Japan B953/P2053 The HOPS/Class C Vps complex tethers autophagosomes to lysosomes/vacuoles by binding simultaneously to the autophagosome surface protein LC3B/Atg8p and to a lysosome/vacuole Rab GTPase. C. Stroupe1; 1Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA

B955/P2055 The cell membrane repair protein dysferlin binds SNAREs and stimulates membrane fusion in a calcium-sensitive manner. C.P. Johnson1, S. Codding1; 1Biochemistry, Oregon State University, Corvallis, OR B956/P2056 A Link to the Past - How endosomal vesicles are captured by Golgins at the TGN. J.J. Shin1, A. Gillingham1, J. Chadwick1, S. Munro1; 1Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom B957/P2057 Yeast dynamin for the fusion of endosome-derived vesicles at the Golgi. P. Makaraci1, H. McDermott1, M. Delgado Cruz1, K. Kim1; 1Biology, Missouri State University, Springfield, MO B958/P2058 WITHDRAWN B959/P2059 Vps1 functions with the GARP tethering complex for endosome-toGolgi traffic. U. Saimani1, J. Smothers1, K. Kim1; 1Biology, Missouri State University, Springfield, MO B960/P2060 Coordination of tethering and fusion machinery by the Golgin protein Coy1. N.S. Anderson1, C. Barlowe1; 1Cell Biology and Biochemistry, Dartmouth College, Hanover, NH B961/P2061 In vitro reconstitution of COG function in membrane tethering and fusion. W. Wang1, T. Kudlyk1, V.V. Lupashin1; 1Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR B962/P2062 Establishing a new role for the MAL2 N-terminal proline-rich domains in actin remodeling and cancer progression. A. Lopez Coral1, E.T. Azurin1, P.L. Tuma1; 1Biology, The Catholic University of America, Washington, DC B963/P2063 Alcohol‐induced tubulin acetylation alters lipid droplet dynamics. J.L. Groebner1, M.M. Girón Bravo1, D.J. Tuma2, P.L. Tuma1; 1Biology, The Catholic University of America, Washington, DC, 2 Internal Medicine, University of Nebraska, Omaha, NE

B944/P2045 Traffic across the nuclear membrane: The cargo shape matters. R. Moussavi-Baygi1, M. Mofrad1; 1Applied Science and Technology, University of California, Berkeley, Berkeley, CA

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TUESDAY

B940/P2041 CRM1 mediates nuclear export of beta dystroglycan to maintain correct nuclear envelope integrity and function. G. Vélez Aguilera1, J. Gómez López1, E. Jiménez Gutiérrez1, A. Vásquez Limeta1, M. Laredo Cisneros1, S.J. Winder2, B. Cisneros-Vega1; 1Genetic and Molecular Biology, CINVESTAV, IPN, Mexico, Mexico, 2 Biomedical Science, University of Sheffield, UK, United Kingdom

B946/P2047 Prolines in the α-helix confer structural flexibility on importin β necessary for nuclear transport. M. Kumeta1, H. Konishi1, S. Yoshimura1; 1Graduate School of Biostudies, Kyoto University, Kyoto, Japan

B954/P2054 TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis and axon branching. C.C. Winkle1, S. Menon2, M. Plooster3, F.L. Urbina3, C. Monkiewicz2, C. Hanlin2, S.L. Gupton2,4,5; 1Neurobiology Curriculum, University of North Carolina, Chapel Hill, NC, 2Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 3Cell Biology and Physiology Curriculum, University of North Carolina, Chapel Hill, NC, 4Neuroscience Center, University of North Carolina, Chapel Hill, NC, 5Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC

Board No./Presentation No. B964/P2064 Chromaffin cell synaptotagmin isoforms belong to spatially and functionally vesicle granule pools. T.C. Rao1, P.J. Dahl1, A.H. Ranski1, M. Schmidtke1, J. Bourg2, S.L. Veatch2, D.R. Giovannucci3, E.R. Chapman4, A. Anantharam1; 1Pharmacology, University of Michigan, Ann Arbor, MI, 2Biophysics, University of Michigan, Ann Arbor, MI, 3 Neuroscience, University of Toledo, Toledo, OH, 4Neuroscience, University of Wisconsin, Madison, WI B965/P2065 Different Munc18 Proteins Mediate Baseline and Stimulated Airway Mucin Secretion. A. Jaramillo1, M.J. Tuvim1, B.F. Dickey1; 1Pulmonary Medicine, MD Anderson Cancer Center, Houston, TX B966/P2066 Roles of Lipid Binding in Polarized Exocytosis Regulated by the OSBP Homologue Osh4p. R.J. Smindak1, M.A. Hand1, G.E. Mantus1, D.M. Hyatt1, R.C. Deutscher1, K.G. Kozminski1,2; 1Biology, University of Virginia, Charlottesville, VA, 2Cell Biology, University of Virginia, Charlottesville, VA B967/P2067 Title: Macropinosomelysosome fusion is a clathrin dependent process in bone marrow derived macrophages. S. Poudel1, L. Huang2, J. Lou2, G. Opoku-kusi2, A.D. Hoppe2, N.W. Thiex1; 1Biology and Microbiology, South Dakota State University, Brookings, SD, 2 Chemistry and Bio-Chemistry, South Dakota State University, Brookings, SD B968/P2068 Coiled-coils as molecular motors: entropic polymer engines. M. Jahnel1,2, D.H. Murray2, M. Zerial2, S.W. Grill1,2; 1BIOTEC, TU Dresden, Dresden, Germany, 2Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany B969/P2069 Exocytosis of Toxoplasma gondii microneme and rhoptry organelles is controlled by the ferlin family of Ca2+sensors. B.I. Coleman1, S. Saha1, E.C. Gray1, D. Tagoe1, M. Gubbels1; 1Biology, Boston College, Chestnut Hill, MA B970/P2070 The Rab27 effector synaptotagmin-like protein 2 interacts with lipids to regulate Weibel-Palade body exocytosis. S.N. Koerdt1, A. Biesemann1, V. Gerke1; 1Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Muenster, Muenster, Germany

Endosomes, Lysosomes, and Lysosome-Related Organelles 2 B971/P2071 Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux. H. Kim1, M. Jang1, R. Park1, J. Park1; 1Division of Biological Science and Technology, Yonsei University, Wonju, Korea, South

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Tuesday Poster Session B972/P2072 Gyp1 mutant cells are defective in autophagy regulation. T. Chang1, W. Huang1; 1Department of Life Science, National Taiwan University, Taipei, Taiwan B973/P2073 Identification and characterization of deubiquitinating enzymes regulate autophagosome formation in Drosophila. G. Chen1; 1Inst Biological Chemistry, Academia Sinica, Taipei, Taiwan B974/P2074 Visualization of the autophagosomal maturation: The ATGconjugation systems are important for degradation of the inner autophagosomal membrane. I. Koyama-Honda1, K. Tsuboyama1, Y. Sakamaki2, M. Koike3, N. Mizushima1; 1Department of Biochemistry and Molecular Biology, The University of Tokyo, Graduate School and Faculty of Medicine, Tokyo, Japan, 2Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 3Departments of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Tokyo, Japan B975/P2075 Identification of Downstream Effectors of Arl1 Function in Macroautophagy. S. Yang1, A. Rosenwald1; 1Biology, Georgetown University, Washington, DC B976/P2076 PLEKHM1 is a shared effector of Rab7 and Arl8b that regulates endosome and autophagosome maturation and lysosome positioning. R. Marwaha1, S.B. Arya2, D. Jagga1,2, H. Kaur2, A. Tuli2, M. Sharma1; 1Department of Biological Sciences, Indian Institute of Science Education and Research (IISER)-Mohali, Mohali, India, 2Division of Cell Biology and Immunology, Institute of Microbial Technology, Chandigarh, India B977/P2077 Proximity-based biotinylation identifies a new role for autophagy in ribonucleoprotein loading into extracellular microvesicles. A.M. Leidal1, H. Huang2, J. Ye1, T. Solvik1, J.Y. Liu1, F. Kai3, J. Goldsmith1, M. Stanley1, T. Marsh1, A. Wiita2, J. Debnath1; 1Department of Pathology, University of California, San Francisco, San Francisco, CA, 2Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, 3Department of Surgery, University of California, San Francisco, San Francisco, CA B978/P2078 Histoplasma capsulatum, an endemic fungal pathogen of humans, manipulates phagosome maturation and the associated cytokine response in macrophages but not dendritic cells. N. Van Prooyen1, C.A. Henderson1, D. Hocking Murray1, A. Sil1; 1Microbiology Immunology, University of California San Francisco, San Francisco, CA

B979/P2079 Atg8 is involved in endosome/ phagosome maturation in the enteric protozoan parasite Entamoeba histolytica. K. Nakada-Tsukui1, E. Miyamoto1,2, N. Watanabe1,2, K. Shibata1, R. Wahyuni1,2, Y. Saito-Nakano1, T. Nozaki1,2; 1Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan, 2Graduate School of Life and Environmental Science, University of Tsukuba, Tsukuba, Japan B980/P2080 Env7 phosphorylation is dependent on Tor1 and Yck3 and is regulated during cell cycle in Saccharomyces cerevisiae. S.P. Manandhar1, S.P. Valencia1, E. Gharakhanian1; 1Biological Sciences, California State University Long Beach, Long Beach, CA B981/P2081 Structure, inhibition, and regulation of a vacuolar two-pore channel TPC1. A.F. Kintzer1, R.M. Stroud1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B982/P2082 Mutations in the vacuolar H+-ATPase bypass the requirement for PI(3,5)P2 in Saccharomyces cerevisiae. Z.N. Wilson1, G. Odorizzi1, M. West1; 1MCDB, University of Colorado Boulder, Boulder, CO B983/P2083 Autophagy enhances glucose uptake during metabolic stress by facilitating retromer-dependent trafficking of Glut1 to the plasma membrane. S. Roy1, A.M. Leidal1, J. Ye1, J. Debnath1; 1Pathology, University of California San Francisco, San Francisco, CA B984/P2084 WHAMM- and Arp2/3-complexdriven endomembrane trafficking during infection. J. Kollasser1, S. Stahnke1, M. Kirchenwitz1, A. Otto1, K. Rottner2, T.E. Stradal1; 1Cell Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany, 2Division of Molecular Cell Biology, Braunschweig University of Technology, Braunschweig, Germany B985/P2085 Screening for inhibitors of endocytosis that influence zebrafish epidermal plasma membrane homeostasis. S. Banerjee1, M.S. Sonawane1; 1Department of Biological Sciences, Tata Institute of Fundamental Research, MUMBAI, India B986/P2086 A potential role for TtSNX4 in macronuclear degradation in Tetrahymena thermophila Conjugation. M. Patterson1, A. Ariatti1, B. McField1, S. Guerrier1; 1Biology, Millsaps College, Jackson, MS B987/P2087 The Contractile Vacuole Polarizes to the Rear of Migrating Dictyostelium. S. Fadil1, K. Smith1, W. Lord1, M. Beshay1, N. Bawazir1, M. Myre2, C.J. Janetopoulos1; 1Cell Biology and Biotechnology, University of the Sciences, Philadelphia, PA, 2Harvard Medical School, Massachusetts General Hospital, Boston, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Membrane Fission and Coat Proteins B1000/P2088 Cryo-CLEM of clathrin coats reveals the architecture of the clathrin lattice during maturation. O. Avinoam1, M. Kaksonen2, J.A. Briggs1,3; 1Structural and Computational Biology Unit, The European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, 2Department of Biochemistry, University of Geneva, Geneva, Switzerland, 3Cell Biology and Biophysics Unit, The European Molecular Biology Laboratory (EMBL), Heidelberg, Germany B1001/P2089 Hot-wiring clathrin-mediated endocytosis in human cells. L.A. Wood1, N.I. Clarke1, S. Sarkar1, S.J. Royle1; 1Centre for Mechanochemical Cell Biology, Warwick Medical School, Coventry, United Kingdom B1002/P2090 Functional recruitment of dynamin requires multimeric interactions with SH3 domain containing proteins for efficient endocytosis. D. Perrais1, M. Rosendale1, T. Van1, D. GrilloBosch1, I. Gauthereau1, D. Choquet1, M. Sainlos1; 1Interdisciplinary Institute for Neuroscience, CNRS and University of Bordeaux, Bordeaux, France B1003/P2091 The structure of the COPI coat determined within the cell. Y.S. Bykov1, M. Schaffer2, S.O. Dodonova1, S. Albert2, J.M. Plitzko2, W. Baumeister2, B.D. Engel2, J.A. Briggs1; 1Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany, 2Max Planck Institute of Biochemistry, Martinsried, Germany

B1005/P2093 Reconstitution of ESCRT membrane remodeling processes with designer lipid membrane systems. I. Lee1, H. Kai2, L. Carlson1, J.T. Groves3, J.H. Hurley1; 1Molecular and Cell BIology, University of California, Berkeley, Berkeley, CA, 2Division of Mechanical Engineering, Tohoku University, Tohoku, Japan, 3Chemistry, University of California, Berkeley, Berkeley, CA

B1006/P2094 Vps4 Induces Dynamic Instability in ESCRT-III Polymers. B. Mierzwa*1, N. Chiaruttini*2, L. RedondoMorata3, J. Moser von Filseck2, J. König4,5, I. Poser6, T. Müller-Reichert4, S. Scheuring3, A. Roux2,7, D.W. Gerlich1; 1Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna, Austria, 2 Department of Biochemistry, University of Geneva, Geneva, Switzerland, 3U1006 INSERM, Aix-Marseille Université, Marseille, France, 4Medical Theoretical Center, Dresden University of Technology, Dresden, Germany, 5Electron Microscopy Unit, Francis Crick Institute, London, United Kingdom, 6 Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany, 7 Swiss National Centre for Competence in Research Programme Chemical Biology, Geneva, Switzerland B1007/P2095 The microtubule severing protein, Spastin, mediates efficient endosomal tubule fission. G.J. Pearson1,2, R. Allison1, J. Lippincott-Schwartz2, E. Reid1; 1Cambridge Institute of Medical Research, Cambridge, United Kingdom, 2 Janelia Research Centre, Ashburn, VA B1008/P2096 The dynamics of chemokine receptor CXCR4 endocytosis. L.K. Rosselli-Murai1, M. DeNies2, M. White3, A.P. Liu1,2,3; 1Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, 2Department of Molecular and Cellular Biology, University of Michigan, Ann Arbor, MI, 3Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI B1009/P2097 A model for the architecture of caveolae based on a flexible, netlike assembly of Cavin1 and Caveolin discs. M. Stoeber1,2, P. Schellenberger3, K. Grünewald3, A. Helenius2; 1Psychiatry, UCSF, San Francisco, CA, 2Biochemistry, ETH Zurich, Zurich, Switzerland, 3Structural Biology, University of Oxford, Oxford, United Kingdom

Polarity in the Development of Tissues and Organisms B1011/P2098 A feedback between cellular growth and polarity in fission yeast. A. Haupt1, D. Ershov1, N. Minc1; 1Insitut Jacques Monod, UMR7592, CNRS, Paris, France B1012/P2099 The Glucan Synthase BGS1 Cooperates with TEA1-TEA4 Complex in the Maintenance of Fission Yeast Polarity. M. Ramos1, I. Barragan1, J.G. Cortés1, B. Moreno1, J. Ribas1, P. Perez1; 1Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas, Salamanca, Spain

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1013/P2100 Rapid asymmetric induction of zygotic transcription prevents refertilization in fission yeast. A. Vjestica1, S.G. Martin1; 1Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland B1014/P2101 Feedback inhibition of Ras activity coordinates cell fusion with cell-cell contact. L. Merlini1, S.G. Martin1; 1Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland B1015/P2102 Sphingolipids Are Required for Mother-specific Retention of Plasma Membrane Proteins in S. cerevisiae. P. Singh1, J. Zhu1, R. Li1; 1Cell Biology, Johns Hopkins school of medicine, Baltimore, MD B1016/P2103 Non-transport functions of the Na+-K+-ATPase beta1 subunit contribute to lung epithelial tight junction formation. H. Bai1,2, M. Barravecchia2, A. Joynt2, A. Friedman2,3, D.A. Dean2; 1Pathology, University of Rochester Medical Center, Rochester, NY, 2 Pediatrics, University of Rochester Medical Center, Rochester, NY, 3Chemistry, The State University of New York at Buffalo, Buffalo, NY B1017/P2104 TTLL12-Dependent Midbody Microtubule Modification Drives Polarized Endosome Targeting During Epithelial Cell Lumenogenesis. A.J. Mangan1, R. Prekeris1; 1Department of Cell and Developmental Biology, University of Colorado, Anschutz Medical Campus, Aurora, CO B1018/P2105 Utilization of lipid droplets is essential for energy production during hepatocyte polarization. S. Kang1, D. Fu1; 1Faculty of Pharmacy, The University of Sydney, Sydney, Australia B1019/P2106 Role of β and γ-catenin in maintaining hepatocyte polarity. T. Pradhan1, S.P. Singh Monga1; 1Pathology, University Of Pittsburgh, Pittsburgh, PA B1020/P2107 Nox1 regulates polarity during cell migration. A. Valdivia 1, C. Duran1, A. San Martin1; 1Medicine, Emory University, Atlanta, GA B1021/P2108 Pumilio-dependent transcript polarization drives chemotaxis. M. Hotz1, W.J. Nelson1; 1Department of Biology, Stanford University, Stanford, CA B1022/P2109 Role of molecular motors and protein phosphatase 2A (PP2A) in cell polarity of the unicellular ciliate Stentor. T. Makushok1, W.F. Marshall1; 1Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA B1023/P2110 LET-99 acts in the Mes-1/Src1 pathway for EMS spindle positioning in C. elegans. M.J. Liro1, A. Hussein 1, L.S. Rose1; 1Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA

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B1004/P2092 Maintenance of EGFR plasma membrane levels involves cargo-specific COPII components of the early secretory pathway machinery. S. Scharaw1, M. Iskar2, A. Ori2, G. Boncompain3,4, V. Laketa1, I. Poser5, E. Lundberg6,7, F. Perez3,4, M. Beck2, P. Bork2,8,9, R. Pepperkok1; 1Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany, 2Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany, 3PSL Research University, Institut Curie, Paris, France, 4CNRS UMR144, Institut Curie, Paris, France, 5Molecular Cell Biology and Genetics, Max Planck Institute, Dresden, Germany, 6KTH-Royal Institute of Technology, Stockholm, Sweden, 7Science for Life Laboratory, Solna, Sweden, 8 Molecular Medicine, Max-Delbrueck-Center, Berlin, Germany, 9Bioinformatics, University of Wuerzburg, Wuerzburg, Germany

Tuesday Poster Session

Board No./Presentation No.

Tuesday Poster Session

B1024/P2111 Single-particle dynamics underlying the segregation of GFP::PIE-1 during asymmetric division of the C. elegans zygote. Y. Wu1, B. Han1, E. Griffin1; 1Biology, Dartmouth College, Hanover, NH

B1032/P2119 Iterating compactions coupled to apical cell polarity oscillations maintain order in proliferating epithelia. K. Ragkousi1, K. Marr1, S. McKinney1, L. Ellington1, M.C. Gibson1; 1Stowers Institute for Medical Research, Kansas City, MO

B1025/P2112 A conserved amino acid cluster in the planar cell polarity protein Van Gogh confers binding to antagonistic effectors and regulates Drosophila polarity establishment. A.C. Humphries1, M. Mlodzik1; 1Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY

B1033/P2120 Genome organizer SATB1 regulates cell polarity of ameloblasts and enamel matrix formation. Y. Zhang1, L. Zheng1, M. Lee1, Y. Nakano1, Y. Kohwi1, S. Habelitz2, R. Marcucio 3, P. [email protected], T. KohwiShigematsu1; 1Department of Orofacial Sciences, University of California San Francisco, San Francisco, CA, 2Preventive and Restorative Dental Sciences, University of California San Francisco, San Francisco, CA, 3Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA

B1026/P2113 HMMR-mediated Ran activity at the centrosome orients neuroprogenitor cell division and is essential for nervous system development. M. Connell1, J. Jiang1, T.C. Lengyell2, H. Chen1, H. Li3, T. Kroll3, A. Fotovati1, T. Chu1, Z. He1, A.M. Li1, D. Goldowitz2,4, M. Patel4, L. Frappart3, G.R. Reid1, E.M. Simpson2, A. Ploubidou3, D.W. Allan5, C.A. Maxwell1; 1Pediatrics, University of British Columbia, Vancouver, BC, 2Centre for Molecular Medicine and Therapeutics, UBC, Vancouver, BC, 3Leibniz Institute on Aging, Jena, Germany, 4Medical Genetics, University of British Columbia, Vancouver, BC, 5Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC B1027/P2114 Apical Polarization of SVCT2 in Apical Radial Glial Cells And Progenitors During Brain Development. F.J. Nualart1, C. Silva-Alvarez1, K.A. Salazar 1 , P. Cisternas1, F.A. Martinez1, N.A. Jara1, R. Bertinat1, N. Saldivia1; 1Center for Advanced Microscopy CMA BIO BIO, Concepcion University, Concepción, Chile B1028/P2115 Influence of cell wall mechanics on cell morphogenesis. V. Davì1, H. Tanimoto1, R. Le Borgne1, H. Guo1, E. Couturier1, A. Boudaoud2, N. Minc1; 1CNRS, Paris, France, 2ENS Lyon, Lyon, France B1029/P2116 Regulation of cell polarity and epithelial morphogenesis by the ciliary GTPase Arl3. S. Bhattarai1, S. Begum1, R. Popow1, E.J. Ezratty1; 1Pathology and Cell Biology, Columbia University, New York City, NY B1030/P2117 Topology Regulates Cell Polarity via Spatial Distribution of Both Adhesions and Actomyosin Contraction. R.S. Fischer1, X. Sun2, W. Losert3, J.T. Fourkas2, C.M. Waterman1; 1Cell Biology and Physiology, National Heart Lung and Blood Institute, Bethesda, MD, 2Chemistry, University of Maryland, College Park, MD, 3 Physics, University of Maryland, College Park, MD B1031/P2118 Cell specification is influenced by endoplasmic reticulum protein, Jagunal, in the Drosophila larval brain. S.A. Beyeler1, B. Riggs1; 1Biology, San Francisco State University, San Francisco, CA

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The Synapse B1035/P2121 Autism susceptibility gene TAOK2 mediates dendritic spine maturation through Septin7 phosphorylation. S. Yadav1,2, J.A. OsesPrieto3, C. Peters1,2, A. Burlingame3, L.Y. Jan1,2, Y.N. Jan1,2; 1Howard Hughes Medical Institute, San Francisco, CA, 2Physiology, University of California San Francisco, San Francisco, CA, 3Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA B1036/P2122 CDC42EP4/BORG4-septin complex beneath perisynaptic membrane domains of Bergmann glial processes facilitates GLAST-mediated glutamate clearance and motor learning. N. AgetaIshihara1, M. Kinoshita1; 1Graduate School of Science, Nagoya University, Nagoya, Japan B1037/P2123 A Genetically-Encoded N-Cadherin Tension Sensor Reveals Localized Tension Associated with Synapse Maturation. K.A. Litwa1,2, A.N. Urs3, A.R. Horwitz2, B.D. Hoffman3; 1Anatomy and Cell Biology, East Carolina University, Greenville, NC, 2Cell Biology, University of Virginia, Charlottesville, VA, 3Biomedical Engineering, Duke University, Durham, NC B1038/P2124 Branched Actin Promotes Synapse Elimination. A.A. CuentasCondori1, D.M. Miller III1,2; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2Neuroscience Program, Vanderbilt University, Nashville, TN B1039/P2125 Investigating the Association of Cyclin G2 with β-catenin Complexes in Neurons. A. Hergarden1, A. Arachchige Don2, K. Kim1, M. Le Marois1, A. De Crescenzo1, T. Patriarchi1, J.W. Hell1,2, M.C. Horne1,2; 1Pharmacology, University of California, Davis, CA, 2Pharmacology, University of Iowa, Iowa City, IA

B1040/P2126 The G protein-coupled receptor FSHR-1 controls excitatory to inhibitory balance at the C. elegans neuromuscular junction. S. Olofsson1, A. Munneke1, A. Wasilk1, J. Kolnik1, E. Damler1, J.R. Kowalski1; 1Biological Sciences, Butler University, Indianapolis, IN B1041/P2127 Investigation of the neuronal functions of the SUMO conjugating enzyme UBC-9 at the C. elegans neuromuscular junction. V. Kreyden1, M. Harrison1, K. Rush1, J.R. Kowalski1; 1Biological Sciences, Butler University, Indianapolis, IN B1042/P2128 The investigation of SYD-2 as a potential substrate of the Anaphase Promoting Complex in promoting GABA release at the C. elegans neuromuscular junction. L. Campagnoli1, J.R. Kowalski1, D. Lester1, K. Rush1; 1Biological Science, Butler University, Indianapolis, IN B1043/P2129 GABAergic neuron-specific loss of PLCγ1 induce handling-induced seizures. H. Kim1; 1BioSignal Network Laboratory, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Korea, South B1044/P2130 Screening for Novel Molecular Contributors to Dopamine Signaling using the Nematode Caenorhabditis elegans Million Mutation Project Library. P. Rodriguez1,2, O. Refai2, R.D. Blakely2; 1Department of Biology, Barry University, Miami Shores, FL, 2Brain Institute and Department of Biomedical Sciences, Charles E. Schmidt College of Medicine, Florida Atlantic University, Jupiter, FL B1045/P2131 Grafting voltage and pharmacological sensitivity in potassium channels. X. Lan1,2, C. Fan2,3, W. Ji2,3, F. Tian1,2, T. Xu2,3, Z. Gao1,2; 1, Shanghai Institute of Materia Medica, CAS, Shanghai, China, 2University of Chinese Academy of Sciences, Beijing, China, 3Institute of Biophysics, CAS, Beijing, China B1046/P2132 Immunofluorescence and freeze-fracture replica immunogold labeling of CNS and PNS axons reveal that Kv1/Cx29 rosettes link axoplasm to myeloplasm in mammalian myelinated axons. J.E. Rash1, K.G. Vanderpool1, T. Yasumura1, J.I. Nagy2; 1Biomedical Sciences, Colorado State University, Fort Collins, CO, 2Physiology, University of Manitoba, Winnipeg, MB B1047/P2133 Exposure to 835MHz Radiofrequency Electromagnetic Field induces Alteration of Synaptic Vesicles in the Hypothalamus of Mice brain. Y. Huh1, J. Kim1, H. Kim1,2, S. Choi1,3, H. Kim2; 1Center for Electron Microscopy Research, Korea Basic Science Institute, Cheongju-si, Korea, South, 2Department of Pharmacology, College of Medicine, Dankook University, Cheonan-si, Korea, South, 3Department of Biological Sciences and Biotechnology, Hannam University, Daejeon, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1048/P2134 Endogenous Nitric oxide decreases sensitization in nervous system of Manduca sexta. F.R. Curiel1; 1Cell and Molecular Biology, San Francisco State University, San Francisco, CA B1049/P2135 The Schizophrenia Susceptibility Factor Dysbindin and its associated BLOC-1 complex functionally and genetically interact with the Arp2/3 Actin polymerization complex at the synapse. A. Gokhale1, C. Hartwig2,3, A. Freeman1, R. Das4, S. Zlatic1, R. Vistein5, A. Burch1, G. Carrot3, A. Lewis1, S. Nelms2, D. Dickman6, M. Puthenveedu5, D. Cox4, V. Faundez1; 1Cell Biology, Emory University, Atlanta, GA, 2Kennesaw State University,, Atlanta, GA, 3Department of Chemistry, Agnes Scott College, Decatur, GA, 4Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA, 5Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, 6fDepartment of Biology, Neurobiology Section, University of Southern California, Los Angeles, CA B1050/P2136 Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function. S.K. Jang1, J.C. Nelson1, E.G. Bend2, L. RodríguezLaureano1, F.G. Tueros3, L. Cartagenova1, K. Underwood1, E. Jorgensen2, D.A. ColónRamos1; 1Cell Biology, Yale University, New Haven, CT, 2Department of Biology, University of Utah, Salt Lake City, UT, 3 Ciencias Biológicas, Universidad Ricardo Palma, Lima, Peru

B1052/P2137 Piezo mechanically activated ion channels regulate cell division and mitochondrial function. H. Miraoui1, J. Xi1, s. Chaturantabut1, H. Qiu1, A. Bennett1, V. Gupta1, W. Goessling1, R. Maas1; 1Medicine - Division of Genetics, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA B1053/P2138 Yeast Ivy1p is a putative I-BAR-domain protein with pH-sensitive filament forming ability in vitro. Y. Itoh1, K. Kida2, K. Hanawa-Suetsugu1,2, S. Suetsugu1,2; 1Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo, Japan, 2 Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan B1054/P2139 Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER. J. Nixon-Abell1,2, C.J. Obara3,4, A.V. Weigel3,4, D. Li3,5, W.R. Legant3, C. Xu3, H. Pasolli3, K. Harvey1, H.F. Hess3, E. Betzig3, C.D. Blackstone2, J. LippincottSchwartz3,4; 1Department of Pharmacology, University College London School of Pharmacy, London, United Kingdom,

Cell Biology Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD, 3Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 4Section on Organelle Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, 5Institute of Biophysics, Chinese Academy of Sciences, Beijing, China 2

B1055/P2140 The ERG2 gene is necessary for the optimal functioning of the Unfolded Protein Response after phenol stress in S. cerevisiae. A. Baris1,2, G. Edwalds-Gilbert1,2; 1Biology, Keck Science Department of Scripps, Claremont Mckenna, and Pitzer Colleges, Claremont, CA, 2 Biology, Scripps College, Claremont, CA B1056/P2141 Changes in location of organelles in cells of different shape regulate calcium signaling dynamics. R. Calizo1, P. Rangamani2, S. Scarlata3, J. Hone4, R. Iyengar1; 1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 2 Department of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA, 3Department of Chemistry and Biochemistry, Worcester Polytechnic Institute, Worcester, MA, 4 Department of Mechanical Engineering, Columbia University, New York, NY B1057/P2142 A yeast perilipin, collaborates with seipin and Fit2 to promote lipid droplet stability, morphology, and accumulation of triglycerides. Q. Gao1, D. Binns1, L. Kinch2, N. Ortiz1, X. Chen1, J.M. Goodman1; 1Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, 2Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX B1058/P2143 Cytoplasmic and Organelle Intermixing upon Cell-to-Cell Fusion. D. Feliciano1,2, C.J. Obara1,2, E. Rieckhoff2,3, L. Lee2,4, H. Rakusova2,5, O. Afonso2,6, G. Adams2,7, J. Lippincott-Schwartz1,2; 1Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, 2Physiology Course, Marine Biological Laboratory, Woods Hole, MA, 3Molecular Cell Biology and Genetics, Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, 4 Applied Physics Department, Harvard University, Cambridge, MA, 5Department of Plant Systems Biology, McGill University, Macdonald Campus, Québec, Canada, 6 IBMC INEB, Institute for Molecular and Cell Biology, Porto, Portugal, 7National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD B1059/P2144 Utilizing 3D printed scaffold to generate a novel Cardiac toxicity Model for screening potential drug candidates. K. Amezcua1, M. Jani1, M.R. Sharma1, C.R. Sharma1, P. Narayanan1, N. Amezcua1, M. Navel1, D. Staton1, H. Wong2, R. Hasson1, J. Kohana2, K. Kramberger1, J. Collins2, F. Douglas1, R. Punzalan1, J. Jani1, J. Sharma1; 1Stem Cell Biology, Celprogen, Torrance, CA, 2bio-engineering, Biopico, Irvine, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1060/P2145 Characterization of organelle localization and dynamics during leader-bleb based motility of melanoma cells under non-adhesive confinement. G. Adams Jr1, J. Logue2, J. LippincottSchwartz3, C.M. Waterman1; 1NHLBI, National Institute of Health, Bethesda, MD, 2 Regenerative and Cancer Cell Biology (RCCB), Albany Medical Center, Albany, NY, 3HHMI Janelia Research Campus, Ashburn, VA B1061/P2146 Mutations in the Sec pathway lead to altered nuclear morphology in Saccharomyces cerevisiae. A.D. Walters1, R. Wang2, O. Gadal2, O. CohenFix1; 1NIDDK, NIH, Bethesda, MD, 2Toulouse University, Toulouse, France B1062/P2147 Quantitative Measure of Effect of PAT Protein Expression on Total Lipid Droplet Volume. S. Yilmaz Dejgaard1, J.F. Presley2; 1Medical Biology, Near East University, Nicosia, Cyprus, 2Anatomy and Cell Biology, McGill University, Montreal, QC B1063/P2148 Super-resolution microscopy reveals protuberance at the ciliary tip when retrograde transport is impaired. J. Yoon1,2, L. Milenkovic3,4, L.E. Weiss2, T. Stearns4, W.E. Moerner1,2; 1Applied Physics, Stanford University, Stanford, CA, 2 Chemistry, Stanford University, Stanford, CA, 3Developmental Biology, Stanford University, Stanford, CA, 4Biology and Genetics, Stanford University, Stanford, CA B1064/P2149 On the Mechanism of GPAT4 Targeting from the Endoplasmic Reticulum to Lipid Droplets. M. Olarte1,2,3, R.V. Farese2,3,4, T. Walther2,3,4,5; 1Cell Biology, Yale University School of Medicine, New Haven, CT, 2Genetics and Complex Diseases, Harvard T.H Chan School of Public Health, Boston, MA, 3Cell Biology, Harvard Medical School, Boston, MA, 4 Broad Institute, Cambridge, MA, 5Howards Hugues Medical Institute, Chevy Chase, United States B1065/P2150 Modulation of ESCRT protein expression modifies domainspecific release of exosomes from cholangiocytes. B.A. Davies1, L.A. Morton2, E.B. Leof3, N.F. LaRusso2, D.J. Katzmann1; 1Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, 2 Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 3Pulmonary and Critical Care, Mayo Clinic, Rochester, MN

Mitochondria, Chloroplasts, and Peroxisomes 3 B1066/P2151 Inhibiting Autophagy prevents Peroxisome Loss in Peroxisome Biogenesis Disorder. K.B. Law1,2, D. Bronte-Tinkew2, E. Di Pietro3, J.H. Brumell2,4, N. Braverman3, P.K. Kim1,2; 1Biochemistry, University of Toronto, Toronto, ON, 2Cell Biology, Hospital for Sick Children, Toronto, ON, 3McGill University, Montreal, QC, 4 Molecular Genetics, University of Toronto, Toronto, ON

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Establishing and Maintaining Organelle Structure 2

Tuesday Poster Session

Board No./Presentation No. B1067/P2152 Biogenesis of peroxisome: Assembly of nascent membrane proteins. Y. Liu1, Y. Yagita2, K. Okumoto2, K. Shinohara2, A. Nagata2, Y. Fujiki1; 1Division of Organelle Homeostasis, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan, 2Department of Biology and Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan B1068/P2153 The effect of the Chloroplast Division Protein ARC3 on FtsZ Assembly. R.S. Shaik1, M. Sung1, S. Vitha2, A. Holzenburg1,2,3,4; 1Biology, Texas AM University, College Station, TX, 2Microscopy Imaging Center, Texas AM University, College Station, TX, 3Biochemistry Biophysics, Texas AM University, College Station, TX, 4Div.of Research, Innovation, and Economic Development, University of Texas Rio Grande Valley, BrownsvilleEdinburg-Harlingen, TX B1069/P2154 Exploring MARS, a collection of Mutants Affecting chloroplast-tonucleus Retrograde Signaling. S. Ramundo1,2,3, K. Perlaza1, M. Lam1,2, M. Jonikas3, P. Walter1,2; 1Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA, 2Howard Hughes Medical Institute, Chevy Chase, MD, 3Department of Plant Biology, Carnegie Institution for Science, Palo Alto, CA B1070/P2155 Regulation of mitochondrial transfer and mitophagy in osteocytes. J. Gao1, T.S. Cheng1, R. Ruan1, T. Wang1, N.J. Pavlos1, A. Qin2, J. Steer3, Q. Jiang4, H. Takayanagi1,5, M. Zheng1; 1Centre for Orthopaedic Research, School of Surgery, University of Western Australia, Perth, Australia, 2Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 3Pharmacology Unit, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia, 4 Department of Sports Medicine and Adult Reconstruction Surgery, Medical School of Nanjing University, Nanjing, China, 5 Department of Immunology, The University of Tokyo, Tokyo, Japan B1071/P2156 The selective autophagy receptor NIX is up-regulated during epidermal keratinocyte differentiation and functions to recruit LC3 to mitochondria to induce mitophagy. C.L. Simpson1, P. Rompolas1, E.L. Holzbaur2; 1Dermatology, University of Pennsylvania, Philadelphia, PA, 2Physiology, University of Pennsylvania, Philadelphia, PA B1072/P2157 Imbalance in phospholipid synthesis in budding yeast leads to abnormal aggregation of mitochondria. K. Power1, O. Cohen-Fix1; 1NIDDK, National Institutes of Health, Bethesda, MD

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Tuesday Poster Session B1073/P2158 Energy Need-Dependent PINK1 Phosphorylates Mitofilin to Maintain Mitochondrial Crista Junctions in a Pathway Linked to Parkinson’s Disease. P. Tsai1, C. Lin2, C. Schoor3, J. COUTHOUIS4, R. Wu2, O. Ross5, A. Gitler4, D. Winter3, X. Wang1; 1Neurosurgery, Stanford University School of Medicine, Palo alto, CA, 2Neurology, National Taiwan University Hospital, Taipei, Taiwan, 3 Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany, 4 Genetics, Stanford University School of Medicine, Palo alto, CA, 5Neuroscience, Mayo Clinic, Jacksonville, FL B1074/P2159 Loss of endogenous PINK1 and Parkin affects cell growth. A.M. Pickrell1, D.P. Sideris1, C. Huang1, C. Wang1, R.J. Youle1; 1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD B1075/P2160 The distribution and phosphorylation of PINK1 and Parkin proteins in mice and rats. H. Wang1, S. Zhang2, C. Ma1, Y. Zhou1; 1RD, AbboMax, San Jose, CA, 2Department of Pathology and Medicine, UT Health Science Center at Houston, Houston, TX B1076/P2161 Investigating the roles of Mulan and Fis1 in Mitophagy. R.E. Huang1,2, D.C. Chan1; 1Biology, California Institute of Technology, Pasadena, CA, 2 Biology, Williams College, Williamstown, CA B1077/P2162 Regulation of Gp78 S538 phosphorylation and Gp78-dependent endoplasmic reticulum-mitochondria association and mitochondrial fission by its extracellular ligand AMF. G. Gao1, C. Pichon1, B. Joshi1, I.R. Nabi1; 1Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC B1078/P2163 Ascl3 cross-talk with Phb1 and Sgk1 in mitochondrial homeostasis. M.T. Garcia-Barrio1, T.P. Callier IV1, A. Driss2, S.C. Francis1, L. Chang3, W.E. Thompson1; 1Physiology, Morehouse School of Medicine, Atlanta, GA, 2Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, GA, 3Medicine, University of Michigan, Ann Arbor, MI B1079/P2164 Adenine Nucleotide Translocase and Actin-Interacting Protein as New Targets in the Protection of Airway Epithelial Cells Against Cigarette Smoke. C.R. Kliment1,2, J. Nguyen1,3, Y. Lu3, J.E. Radder4, S.M. Claypool5, S.D. Shapiro4, R. Sidhaye2, D.N. Robinson1; 1Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD, 2Pulmonary Critical Care, Johns Hopkins School of Medicine, Baltimore, MD, 3Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, 4Pulmonary Critical Care, University of Pittsburgh, Pittsburgh, PA, 5Physiology, Johns Hopkins School of Medicine, Baltimore, MD

B1080/P2165 Drafting the mitochondrial proteome. M. Wiking1, M. Uhlén1, E. Lundberg1; 1Affinity Proteomics, Science for Life Laboratories (KTH), Solna, Sweden B1081/P2166 Vespa amino acid mixture augments oxidative phosphorylation and induces oxidative stress, leading to mitochondrial membrane degradation and activating apoptotic signaling. S.B. Redmond1, A.I. Mohamed1, S.R. Stowers1, K. Clark1, M. Dameron1, E. Grandy1, J. Davis1; 1Biology, Radford University, Radford, VA B1082/P2167 Pro-apoptotic Bax molecules densely populate the edges of membrane pores. T. Kuwana1, N.H. Olson2, W.B. Kiosses1, B. Peters1, D.D. Newmeyer1; 1La Jolla Institute for Allergy and Immunology, La Jolla, CA, 2CryoEM Core Facility, University of California San Diego, La Jolla, CA B1083/P2168 Engineering phagocytosis to understand conserved mechanisms of membrane-proximal signal transduction. A.P. Williamson1, M.A. Morrissey1, R.D. Vale1; 1Cellular and Molecular Pharmacology, UCSF/HHMI, San Francisco, CA B1084/P2169 Discovery of novel subunits in the mitochondrial calcium uniporter complex of Trypanosoma brucei. G. Huang1, R. Docampo1; 1Center for Tropical and Emerging Global Diseases and Department of Cellular Biology, University of Georgia, Athens, GA B1085/P2170 INA complex links assembly of the nuclear- and mitochondrialencoded modules of ATP synthase. N. Naumenko1, P. Rehling1,2; 1Department of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany, 2 Max Planck Institute for Biophysical Chemistry, Goettingen, Germany B1086/P2171 Role for Rtg2p carboxyterminus in retrograde signaling. J. Jiang1, L. Nunes1, D.M. Gordon1; 1Biological Sciences, Mississippi State University, Mississippi State, MS B1087/P2172 Glycolytic acetyl-CoA production is dispensable for myelination. G. Della Flora Nunes1,2, L. Mueller1, E. Hurley1, N. Silvestri3, K. Nave4, M. Patel2, L. Wrabetz1,2,3, M. Feltri1,2,3, Y. Poitelon1,2; 1Hunter James Kelly Research Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, 2Departament of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, 3Departament of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, 4Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Rho-Family GTPases B1100/P2173 Regulation of circular dorsal ruffles, macropinocytosis and cell migration by RhoG and its exchange factor Trio. A. Valdivia1,2, S.M. Goicoechea1, R. Garcia-Mata1; 1Department of Biological Sciences, University of Toledo, Toledo, OH, 2 Division of Cardiology, Emory University, Atlanta, GA B1101/P2174 A RhoG-mediated signaling pathway that modulates invadopodia formation in breast cancer cells. S.M. Goicoechea1, A.E. Zinn1, K.L. Snyder1, S. Awadia1, R. Garcia-Mata1; 1Department of Biological Sciences, University of Toledo, Toledo, OH B1102/P2175 SPV-1, a RhoGAP with a novel F-BAR domain, regulates calcium signaling in the C. elegans spermatheca during ovulation events. J. Bouffard1, A.R. Asthagiri1,2, R. Zaidel-Bar3,4, E.J. Cram5; 1Bioengineering, Northeastern University, Boston, MA, 2Chemical Engineering, Northeastern University, Boston, MA, 3Biomedical Engineering, National University of Singapore, Singapore, Singapore, 4Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 5Biology, Northeastern University, Boston, MA

Tuesday Poster Session B1107/P2180 Identification of novel RhoA binding proteins by using BioID system. A. Kushiya1, Y. Kato1, S. Yamada2, K. Yoshino3, A. Takeuchi4, M. Yamanoue1, Y. Shirai1, S. Ueda1; 1Agrobioscience, Kobe University, Kobe, Japan, 2Biomedical Engineering, University of California, Davis, Davis, CA, 3Biosignal Research Center, Kobe University, Kobe, Japan, 4Analytical Laboratory, Kobe Pharmaceutical University, Kobe, Japan B1108/P2181 Cdc42 regulates enucleation of human erythroblasts. K. Ubukawa1, T. Goto2, I. Kobayashi1, Y. Guo1, K. Asanuma3, N. Takahashi1, H. Wakui2, W. Nunomura2,4; 1Dept. of Hematol., Nephrol., Rheumatol., Akita Univ., Akita, Japan, 2Dept of Life Sci., Akita Univ., Akita, Japan, 3Center for RI, BERSC, Akita Univ., Akita, Japan, 4 Res. Center for Engin. Sci., Akita Univ., Akita, Japan B1109/P2182 The dual Rho GEF/Rac GAP protein Bcr regulates p38 MAPK signaling and cancer cell growth. S.E. Kohrt1, A.D. Dubash1; 1Biology, Furman University, Greenville, SC

Kinases and Phosphatases 2 B1110/P2183 Utilization of Akt isoform specific multiplex assays to quantitate Akt1/pAkt1, Akt2/pAkt2, Akt3/pAkt3 levels in mouse and human models. W. Lie1, A. Saporita1, M. Schluter1, J. Hwang1; 1MilliporeSigma, St Louis, MO

B1104/P2177 Pattern formation of Rho GTPase effectors during single cell wound healing. A. Moe1, M.E. Larson2, W.M. Bement3,4; 1Graduate Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, WI, 2 Medical Scientist Training Program, University of Wisconsin Madison, Madison, WI, 3Department of Zoology, University of Wisconsin Madison, Madison, WI, 4 Laboratory of Cell and Molecular Biology, University of Wisconsin Madison, Madison, WI

B1111/P2184 A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues. T.H. Mann1,2, W.S. Childers3, J.A. Blair4, M.R. Eckart5, L. Shapiro1; 1Developmental Biology, Stanford University, Stanford, CA, 2 Biochemistry, Stanford University, Stanford, CA, 3Chemistry, University of Pittsburgh, Pittsburgh, PA, 4Chemistry, Williams College, Williamstown, MA, 5Protein and Nucleic Acid Facility, Stanford University, Stanford, CA

B1105/P2178 RhoGDI Phosphorylation by PKCβ Promotes Cdc42 Activation During Cell Wound Repair. A.E. Golding1, W.M. Bement1,2,3; 1Graduate Program in Cell and Molecular Biology, University of Wisconsin-Madison, Madison, WI, 2 Laboratory of Cell and Molecular Biology, University of Wisconsin-Madison, Madison, WI, 3Department of Zoology, University of Wisconsin-Madison, Madison, WI B1106/P2179 Unique Modalities of MAP Kinase Signaling Generates Specificity Among Pathways That Share Components. S. Basu1, B. Li1, P.J. Cullen1; 1Biological Sciences, University at Buffalo, The state University of New York, Buffalo, NY

B1112/P2185 PKA inhibition restores adenosine uptake in renal tubular epithelial cells under high D-glucose conditions. W. Garrido1, J. Catalan1, S. Alarcon1, R. San Martín1; 1Facultade de Ciencias, Universidad Austral de Chile, Valdivia, Chile B1113/P2186 Single Molecule Analysis of Allosteric Interactions in Protein Kinase A. Y. Hao1, J. England1, S.S. Taylor2,3, R.A. Maillard1; 1Department of Chemistry, Georgetown University, Washington, DC, 2 Department of Pharmacology, University of California, San Diego, La Jolla, CA, 3 Department of Chemistry Biochemistry, University of California, San Diego, La Jolla, CA B1114/P2187 Mimicking transient activation of protein kinases in living cells. J. Klomp1, A. Ray1, V. Huyot1, K.B. Collins1, A.V. Karginov1; 1Pharmacology, University of Illinois - Chicago, Chicago, IL

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1116/P2189 Novel insights into regulation of Target of Rapamycin Complex 2 by hyperosmotic stress. K.L. Leskoske1, F.M. Roelants1, J.W. Thorner1; 1Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA B1117/P2190 Novel approach for rapid development of optimized FRETbased biosensor for signaling network interrogation in cellulo and in vivo. F. Sipieter1,2, B. Cappe1,2, O.C. Gavet3, L. Heliot4, P. Vandenabeele1,2, P. Vincent5, F.B. Riquet1,2,6; 1Molecular Signaling and Cell Death Unit, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium, 2Molecular Signaling and Cell Death Unit, Inflammation Research Center (IRC), a VIB-UGent department, VIB, Ghent, Belgium, 3Institut Gustave Roussy (IGR), CNRS-UMR 8200, CNRS/ Paris-Sud University, Villejuif, France, 4Team Biophotonique Cellulaire Fonctionnelle, Laboratoire de Physique des Lasers, Atomes et Molécules (PhLAM), CNRS UMR 8523, CNRS/Lille1 University, Villeneuve d’Ascq, France, 5Neurobiologie des processus adaptatifs (NPA), CNRS UMR 7102, CNRS / UPMC Paris 6, Paris, France, 6 Structural and Functional Glycobiology Unit (UGSF), CNRS UMR 8576, Lille 1 University, Villeneuve d’Ascq, France B1118/P2191 Phospholipase C-related but Catalytically Inactive Protein, PRIP is Involved in the Regulation of Insulin Signaling via IRS-1/Akt Pathway by Modulating Serine Phosphorylation of IRS-1. J. Gao1, A. Mizokami1,2, M. Hirata1; 1Laboratory of Molecular and Cellular Biochemistry, Faculty of Dental Science, Kyushu University, Fukuoka, Japan, 2OBT Research Center, Faculty of Dental Science, Kyushu University, Fukuoka, Japan B1119/P2192 Pharmacological activation of p70 S6 Kinase in C2C12 myotubes. K. Sakamoto1, S. Tanaka1; 1Department of Pharmacology, Fukushima Medical University School of Medicine, Fukushima, Japan B1120/P2193 A single-molecule approach to deciphering the mechanism of T-cell receptor triggering. K.A. Ganzinger1, R. Fernandes2, S. Lee1, M. Palayret1, P. Jönsson1, J. McColl1, S.J. Davis2, D. Klenerman1; 1Chemistry, University of Cambridge, Cambridge, United Kingdom, 2 Radcliffe Department of Medicine and MRC Human Immunology Unit, University of Oxford, Oxford, United Kingdom

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B1103/P2176 Rho GTPases signaling: from cytoskeleton regulation to nuclear DNA damage response and repair. F.L. Forti1, Y.T. Magalhaes1; 1Department of Biochemistry, Institute of Chemistry, University of Sao Paulo, Sao Paulo, Brazil

B1115/P2188 Suppressor of IKK epsilon (SIKE) links the cytoskeleton to innate immune signaling pathways. H.A. Sonnenschein1, F. Slykas1, K.F. Lawrence2, J.K. Bell1; 1Chemistry Biochemistry Department, University of San Diego, San Diego, CA, 2Immunology Microbiology Department, Virginia Commonwealth University, Richmond, VA

Board No./Presentation No. B1121/P2194 PLK4 targets growth arrest and DNA damage-inducible protein 45 alpha (GADD45a). N.J. Gosselin1, G. Sivakumar1, B. Wu1, R.A. Ward1, A. Kozarova1, J.W. Hudson1; 1Biological Sciences, University of Windsor, Windsor, ON B1122/P2195 KANPHOS (KinaseAssociated Neural PHOspho-Signaling), a comprehensive database for specific substrates of kinases. T. Takano1, J. Yoshimoto2, T. Kannon3, T. Nishioka1, M. Amano1, K. Kaibuchi1; 1Department of Cell Pharmacology,, Nagoya University Graduate School of Medicine, Nagoya, Japan, 2Graduate School of Information Science, Nara Institute of Science and Technology, Nara, Japan, 3Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan B1123/P2196 Conserved tyrosine residue in MAPKK Ste7 regulates kinase activity during mating signal transduction. N. Lee1, S. Park1; 1Department of Biological Sciences, Seoul National University, Seoul, Korea B1124/P2197 STK25 is a novel kinase activator of LATS-YAP signaling. S. Lim1, T. Mudianto1, B.W. Howell2, N.J. Ganem1; 1Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, 2Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY B1125/P2198 TRAF2 and NCK-interacting protein kinase (TNIK) as a molecular target of ponatinib- induced endothelial apoptosis and inflammation. N. Le1, K. Fujiwara1, J. Abe1; 1Cardiology, University of Texas MD Anderson Cancer Center, Houston, TX

Signaling Receptors (RTKs and GPCRs) 2 B1126/P2199 PKC-ζ regulates thrombininduced proliferation of human Müller Glial Cells. I. Lee-Rivera1, E.C. LopezHernandez1, A. López-Colomé1; 1Instituto de Fisiología Celular UNAM, Mexico, Mexico B1127/P2200 Effect of NVPAEW541 and RAD001 on Cell Growth and Apoptosis in two Pancreatic Adenocarcinoma Cell lines. G.S. Warshamana-Greene1, A. Panthi1; 1Biological & Physical Sciences, South Carolina State University, Orangeburg, SC

Tuesday Poster Session B1128/P2201 A DNA based T cell receptor reveals the mechanistic role of spatial organization in ligand discrimination. M.J. Taylor1,2,3, K. Husain3, Z.J. Gartner4, S. Mayor1,3, R.D. Vale1,2; 1HHMI Summer Institute, Woods Hole, MA, 2Molecular and Cellular Pharmacology, University of California San Francisco, San Francisco, CA, 3Cellular Organization and Signalling, National Centre for Biological Sciences, Bangalore, India, 4Dept. of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA B1129/P2202 A novel signaling mechanism for plasma serotonin and the serotonin transporter in the remodeling of cellcell junctions during microvascular leakage. A. Cooper1, P. Mayeux2, F. Kilic1; 1Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, 2Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR B1130/P2203 Lipocalin-2 modulates EGFR recycling to cell membrane after a TGF-a stimulation. L. Yammine1, W. Baron1, F. Terzi1, M. Gallazzini1; 1U1151, INSERM, Paris, France B1131/P2204 Examining Spatial Organization of the Phagocytic Synapse: Segregation of the ‘Don’t Eat Me’ Receptor SIRPA during Engulfment. M.A. Morrissey1, A.P. Williamson1, R.D. Vale1; 1Cell and Molecular Pharmacology, UCSF, San Francisco, CA B1132/P2205 Identification and functional study of novel IRAK1-IKK cascade signaling inhibitor, linQ. K. Kang1, H. Byun1, M. Won1, K. Park1, S. Lee1, G. Hur1; 1Medical Science, Chungnam Medical University, Daejeon, Korea, South B1133/P2206 Phosphorylation of cortactin at Y446 residue is required for G protein-coupled receptor agonistinduced nuclear export and degradation of p21Cip1. J. Janjanam1, G.N. Rao1; 1Department of Physiology, University of Tennessee Health Science Center, Memphis, TN B1134/P2207 Constructing Interactomes of Human and Drosophila ARRDC Family Proteins. I.K. Pranoto1, Y. Kwon1; 1Biochemistry, University of Washington, Seattle, WA B1135/P2208 Measuring dynamic cAMP levels using cADDis, a live-cell assay for Gs and Gi signaling with improved sensitivity. S.E. Tillo1, P.H. Tewson1, T.E. Hughes1, S.A. Martinka1, A.M. Quinn1; 1Montana Molecular, Bozeman, MT B1136/P2209 MCH Receptor 1 Signaling Influences Adipocyte Differentiation Which Influences MCH Receptor 1 Signaling: A GPCR Adapting To A Changing Cellular Environment. H.D. Ophardt1, C. King1, H. Abdullah1, L. Galbier1, R. Shen1, L.B. Cook1; 1Biology, The College at Brockport, SUNY, Brockport, NY

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B1137/P2210 The spatial organization of receptor tyrosine kinase signaling by clathrin-coated pits at the plasma membrane. S. Lucarelli1, G. Judge1, C.N. Antonescu1, J. Abousawan1; 1Chemistry and Biology, Ryerson University, Toronto, ON B1138/P2211 Phospholipase Cβ1 is essential in potentiation of glucosestimulated insulin secretion in pancreatic β-cell. H. Hwang1, H. Jang1, P. Suh1; 1Life Science, Ulsan National Institute of Science and Technology, Ulsan, Korea, South B1139/P2212 Involvement of specific Akt isoforms in the decidualization mechanisms of Human Immortalized Endometrial Stromal Cells. P. Adam1, K. Grenier1, F. Fabi1, S. Parent1, V. Leblanc1, E. Asselin1; 1Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC B1140/P2213 Ligand mediated switch in trafficking of the GIP-receptor: implication for a disease related natural human variant. N. Abdullah1, D. Soares1, J. Dittman1, T.E. McGraw1; 1Biochemistry, Weill Cornell Medicine, New York, NY

Mechanotransduction 2 B1141/P2214 Intercellular communication pathways are hijacked by bacterial pathogens during cell-to-cell spread. R. Lamason1, E.E. Bastounis2, N. Kafai1, R. Serrano3, J.C. Del Alamo3, J.A. Theriot2, M.D. Welch1; 1MCB, University of California, Berkeley, Berkeley, CA, 2Microbiology and Immunology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, 3 Mechanical and Aerospace Engineering Department, University of California San Diego, La Jolla, CA B1142/P2215 Cell-cell fusion is a mechanical process driven by actinpropelled protrusion, mechanosensing, and actomyosin contractility. J. KIM1, E. Chen1; 1Molecular Biology and Genetics, Johns Hopkins University, Baltimore, MD B1143/P2216 Curvotaxis directs cell migration through cell-scale topographical landscapes. L. Pieuchot1, M. Vassaux2, T. Cloatre1, I. Brigaud1, T. Petithory1, J. Milan2, M. Bigerelle3, K. Anselme1; 1IS2M, CNRS UMR 736, Mulhouse, France, 2ISM, CNRS UMR 7287, Marseille, France, 3LAMIH, CNRS UMR 8201, Valenciennes, France B1144/P2217 Investigating the role of turgor pressure in fission yeast growth. B. Knapp1, E.R. Rojas2, K.C. Huang2, F. Chang1; 1Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, 2Bioengineering, Stanford University, Stanford, CA B1145/P2218 Interplay between mechanical tensile forces and Notch activation following asymmetric cell division. R. Le Borgne1, M. Pinot1, K. Bellec1; 1Epithelia Dynamics and Mechanics, CNRS UMR 6290-Institute of Genetics and Development, Rennes, France

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1146/P2219 Mechanical tuning of T lymphocyte responses. M. Saitakis1,2, S. Dogniaux1,2, N. Bufi3, C. Goudot1,2, M. Maurin1,2, A. Asnacios3,4, C. Hivroz1,2; 1 INSERM U932, Institut Curie Section Recherche, Paris, France, 2PSL Research University, Paris, France, 3Laboratoire Matières et Systèmes Complexes, Université Paris-Diderot, Pa, France, 4UMR 7057, CNRS, Paris, France B1147/P2220 Mechanics of T lymphocytes: activation, cytotoxicity, and membrane rupture. L. Guillou1, A. Sawicka1, A. Babataheri1, S. Dogniaux2, A.I. Barakat1, C. Hivroz2, J. Husson1; 1Hydrodynamics Laboratory (LadHyX), Ecole polytechnique, Palaiseau, France, 2Immunity and Cancer, Institut Curie Section Recherche, PSL Research University, INSERM U932, Paris, France B1148/P2221 Single molecular force sensitivity and threshold for the activation of B cell receptors. W. Liu1, Z. Wan1; 1School of Life Sciences, Tsinghua University, Beijing, China B1149/P2222 Physical cues direct the shape of cell processes independently during oligodendrocyte myelin sheath formation. M.E. Bechler1, C. ffrenchConstant1; 1MRC Centre for Regenerative Medicine, The University of Edinburgh, Edinburgh, United Kingdom B1150/P2223 Force fluctuations in threedimensional suspended fibroblasts. F. Rehfeldt1, F. Schlosser1, C.F. Schmidt1; 13rd Institute of Physics - Biophysics, GeorgAugust-University, Göttingen, Germany

B1152/P2225 Treadmilling stress fibers couple cytoskeletal dynamics to cellular traction in a 3D extracellular matrix. L.M. Owen1, A.S. Adhikari2, M. Patel3, P. Grimmer4, M. Kim2, N. Leijnse2, J. Notbohm4, C. Franck3, A.R. Dunn2; 1Biophysics, Stanford University, Stanford, CA, 2Chemical Engineering, Stanford University, Stanford, CA, 3School of Engineering, Brown University, Providence, RI, 4Engineering Physics, University of Wisconsin-Madison, Madison, WI B1153/P2226 Extracellular matrix synthesis and remodeling by mechanical forces in cultured endothelial cells and in arteries of atherosclerotic mice. T.A. Russo1, M.L. Ferreira1, M.E. Perrud1, H.B. Nader1, J.L. Dreyfuss1,2; 1Biochemistry, Universidade Federal de São Paulo, São Paulo, Brazil, 2 Health Informatics, Universidade Federal de São Paulo, São Paulo, Brazil

B1154/P2227 Rigidity of silicone substrates controls cell spreading and stem cell differentiation. E. Gutierrez1, A. Groisman1, E. Tkachenko2, G.K. Vertelov3, E. Ronan1; 1Physics, University of California, San Diego, San Diego, CA, 2Medicine, University of California, San Diego, San Diego, CA, 3Stemedica, San Diego, CA B1155/P2228 STIM1-induced conformational transition of Orai-1 leads to channel activation. Z. Haydari1, H. Shams1, M. Mofrad1; 1Bioengineering, University of California Berkeley, Berkeley, CA B1156/P2229 Leveraging interfacial mechanics for preventing breast cancer progression through tissue architecture stabilization. V. Srivastava1, J. Garbe1,2, J.L. Hu1, M.A. LaBarge2,3, Z.J. Gartner1; 1Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 2Life Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 3Beckman Research Institute of City of Hope, Duarte, CA B1157/P2230 Allosteric effect of α-actinin binding to Vh on vinculin activation. H. Shams1, M. Mofrad1; 1Bioengineering, University of California, Berkeley, Berkeley, CA B1158/P2231 Cellular geometry and cytoskeletal network architecture regulate the mechanics of single stress fibers. E. Kassianidou1,2, C.A. Brand3, U.S. Schwarz3, S. Kumar1,2; 1UC Berkeley-UCSF Graduate Program in Bioengineering, Berkeley, United States, 2Bioengineering, UC Berkeley, Berkeley, CA, 3Institute for Theoretical Physics and BioQuant, Heidelberg University, Heidelberg, Germany B1159/P2232 Multiparametric BioAFM Imaging with Simultaneous Advanced Optical Microscopy. D.R. Stamov1, C. Gonnermann2, C.A. Wurm3, S.B. Kaemmer4, C.M. Franz2, H. Haschke1; 1JPK Instruments AG, Berlin, Germany, 2DFG-Center for Functional Nanostructures (CFN), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany, 3Abberior Instruments, Göttingen, Germany, 4JPKInstruments USA Inc., Carpinteria, CA B1160/P2233 Control of Cell Traction and Migration by Microtubule-Targeting Agents. L.S. Prahl1, P.F. Bangasser1, M. Hemmat1, S.S. Rosenfeld2, D.J. Odde1; 1Biomedical Engineering, University of Minnesota, Minneapolis, MN, 2Cancer Biology, Lerner Research Institute of the Cleveland Clinic, Cleveland, OH B1161/P2234 Investigating the Role of ROCK Isoforms in Regulation of Stiffness Induced Myofibroblast Differentiation in Lung Fibrosis. S. Htwe1, A. Knox2, A. Ghaemmaghami1; 1School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom, 2Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1162/P2235 Transient mechanical strain down-regulates integrin β3 to promote the maturation of invadopodia and enhance cancer cell invasion invitro. A.N. Gasparski1, S. Ozarkar1, K.A. Beningo1; 1Biological Sciences, Wayne State University, Detroit, MI B1163/P2236 Role of caveolae mechanics in muscular dystrophy pathophysiology. M. Dewulf1, C. Blouin1, D.V. Koester2, B. Sinha3, A. Bigot4, G. Butler-Browne4, C. Lamaze1; 1UMR3666, Institut Curie, Paris, France, 2NCBS, Bangalore, India, 3 University of Calcutta, Calcutta, India, 4 UMRS 974, Institut de myologie, Paris, France B1164/P2237 Effects of Mechanical Stress on Remodeling of Periodontal Ligament. A. Fujita1,2, M. Morimatsu2, K. Takahashi2, S. Takashiba1, K. Naruse2; 1Department of Pathophysiology-Periodontal Science, Okayama University Graduate School of Med, Dent and Pharmaceutical Sciences, Okayama, Japan, 2Department of Cardiovascular Physiology, Okayama University Graduate School of Med, Dent and Pharmaceutical Sciences, Okayama, Japan B1165/P2238 Integration of mechanotransduction and T-cell activation thresholds: the effects of mechanical forces on assembly and integration of the signal transduction machinery during T cell activation. M.A. Nelman-Gonzalez1, S.J. Clemett2, A.J. Beitman1, M.R. Alexander3, C.L. Merrill3, B.E. Crucian4, C.F. Sams4; 1Biomedical Sciences and Environmental Research, KBRWyle, Houston, TX, 2Lunar Planetary Sciences, Jacobs, Houston, TX, 3Human Research Program, National Research Council, Houston, TX, 4Biomedical Sciences and Environmental Research, NASA Johnson Space Center, Houston, TX

Dynamics of Focal Adhesions and Invadosomes B1200/P2239 p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway. P. Jeannot1, A. Nowosad1, R. Perchey1, A. Besson1; 1CRCT UMR 1037 INSERM-Universite Paul Sabatier, Cancer Research Center of Toulouse, Toulouse, France B1201/P2240 S100A4 Regulates Podosomes and MMP9 Secretion by Distinct Myosin-Dependent and Independent Mechanisms. N.G. Dulyaninova1, A. Chang1, J.M. Backer1,2, A.R. Bresnick1; 1Biochemistry, Albert Einstein College of Medicine, Bronx, NY, 2 Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY

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B1151/P2224 In-plane shear strain induces epithelial reorganization. M.A. Garcia1, E. Sadeghipour1,2, W.J. Nelson1,3, B.L. Pruitt2,3,4; 1Biology, Stanford University, Stanford, CA, 2Mechanical Engineering, Stanford University, Stanford, CA, 3 Molecular and Cellular Physiology, Stanford University, Stanford, CA, 4Bioengineering, Stanford University, Stanford, CA

Tuesday Poster Session

Board No./Presentation No. B1202/P2241 Particle drag force (PDF): a novel technique for high-precision measurement of molecular tension and force at sub-pN scale. S. Park1, M. Pittman1, Y. Chen1; 1Mechanical Engineering, Johns Hopkins University, Baltimore, MD B1203/P2242 Two distinct actin networks mediate traction oscillations to confer mechanosensitivity of focal adhesions. Z. Wu1, S.V. Plotnikov2, A.Y. Moalim2, C.M. Waterman1, J. Liu1; 1NHLBI, NIH, Bethesda, MD, 2Department of Cell Systems Biology, University of Toronto, Toronto, ON B1204/P2243 Caveolae-independent Caveolin-1 translocation to focal adhesions upon melanoma adhesion and spreading. R. Ortiz1, A. Cardenas1, L. Leyton1, A.F. Quest1; 1Laboratory of Cellular Communication, Center for Molecular Studies of the Cell (CEMC), Advanced Center for Chronic Diseases (ACCDiS), Faculty of Medicine, Universidad de Chile, Santiago, Chile B1205/P2244 Tyrosine phosphorylated caveolin-1 regulates vinculin tension in focal adhesions through its scaffolding domain. F. Meng1, S. Saxena1, B. Joshi1, J. Shankar1, K. Moon2, L.J. Foster2, P.N. Bernatchez3,4, I.R. Nabi1; 1Department of Cell and Developmental Biology, Life Sciences Institute, University of British Columbia, Vancouver, BC, 2Department of Biochemistry Molecular Biology and Michael Smith Labs, Centre for HighThroughput Biology, University of British Columbia, Vancouver, BC, 3Institute for Heart + Lung Health, St Paul’s Hospital, The James Hogg Research Centre, Vancouver, BC, 4Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC B1206/P2245 The small GTPase RhoG modulates focal adhesion turnover. A.E. Zinn1, S.M. Goicoechea1, R. GarciaMata1; 1Biological Sciences, University of Toledo, Toledo, OH

Tuesday Poster Session B1209/P2248 Tensin 3 activates the Rac exchange factor Dock5 to drive the assembly of podosome superstructures in osteoclast and to control bone resorption. H. Touaitahuata1, A. Morel1, S. Urbach2, J. Mateos-Langerak3, S. De Rossi3, A. Blangy1; 1CRBM CNRS UMR 5237, Montpellier University, Montpellier, France, 2 Functional Proteomics Platform, CNRS UMR 5203, Montpellier, France, 3Montpellier RIO Imaging, CNRS UMS3426 Biocampus, Montpellier, France B1210/P2249 Filamin, migfilin and kindlin form a link between the extracellular matrix and the actin cytoskeleton at mature focal adhesions. M. Preciado López1, W. Shin2, D.A. Calderwood2, C.M. Waterman2; 1National Heart Lung and Blood Institute, NIH, Bethesda, MD, 2Yale University School of Medicine, New Haven, CT B1211/P2250 Talin’s Coordination of the Focal Adhesion Network. D.M. Jethwa1; 1Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

Chemotaxis and Directed Cell Migration B1212/P2251 The effect of multiple diatom species on responses to high-light irradiation. S.A. Cohn1, K. Patterson1, A. Wolske1; 1Biological Sciences, DePaul University, Chicago, IL B1213/P2252 Proper actin network architecture is essential for restricting polarization to a single leading edge in neutrophils. B.R. Graziano1, A. Diz-Muñoz2, O.D. Weiner1; 1Cardiovascular Research Institute, UCSF, San Francisco, CA, 2Cell Biology and Biophysics, EMBL, Heidelberg, Germany

B1207/P2246 Formin-dependent Adhesions are required to Initiate Invasion by Intact Epithelia. T. Fessenden1,2,3,4, M. PerezNeut1,5, G.R. Ramirez-SanJuan2,3,4,6, Y.M. Beckham2,3,4, M.L. Gardel1,3,4; 1Committee on Cancer Biology, University of Chicago, Chicago, ID, 2Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, 3Department of Physics, University of Chicago, Chicago, IL, 4James Franck Institute, University of Chicago, Chicago, IL, 5Ben May Department for Cancer Research, University of Chicago, Chicago, IL, 6Graduate Program on Biophysical Sciences, University of Chicago, Chicago, IL

B1214/P2253 The impact of WAVE-complex deficiency on macrophages and the immune system. S. Stahnke1, D.J. de Gorter2,3, F. Lai2,4, O. Kershaw5, A. Gruber5, K. Rottner1,6, T.E. Stradal1,2; 1Department of Cell Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany, 2 Institute for Molecular Cell Biology, University of Münster, Münster, Germany, 3 Institute of Experimental Musculoskeletal Medicine, University Hospital Münster, Münster, Germany, 4Department of Surgery, University of Hong Kong, Hong Kong, Hong Kong, 5Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany, 6 Zoological Institute, Technische Universität Braunschweig, Braunschweig, Germany

B1208/P2247 Alterations in Basal Lamina Stiffness Lead to Impaired Epithelial Cell Migration. O.E. Onochie1, C.B. Rich1, V. Trinkaus-Randall1,2; 1Biochemistry, Boston University School of Medicine, Boston, MA, 2 Ophthalmology, Boston University School of Medicine, Boston, MA

B1215/P2254 Sphingosine 1-phosphate receptor 1 is necessary for collective lymphatic endothelial cell migration in response to fluid shear stress. V.N. Surya1, E. Michalaki1, E. Huang1, G.G. Fuller1, A.R. Dunn1; 1Chemical Engineering, Stanford University, Stanford, CA

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B1216/P2255 Angiopoitein-1 Promotes Endothelial Cell Polarization and Angiogenic Sprouting Through a PAK2- and Paxillin-Dependent CDC42 Activation. C. Boscher1, J. Gratton1; 1Phamacology, Université de Montréal, Montréal, QC B1217/P2256 Exosome secretion promotes chemotaxis of cancer cells. B. Sung1, A.M. Weaver1,2,3; 1Cancer Biology, Vanderbilt University, Nashville, TN, 2Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 3Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN B1218/P2257 Chemotaxis in the absence of gradients. D.A. Knecht1; 1Molecular and Cell Biology, University of Connecticut, Storrs, CT B1219/P2258 Contact Guidance in Breast Cancer Cells Depends on Substrate Flexibility and Correlates with Myosin Phosphorylation on Stress Fibers. I.C. Schneider1, J. Wang1, J. Nuhn1; 1Chemical and Biological Engineering, Iowa State University, Ames, IA B1220/P2259 Multiscale Cues Drive Collective Cell Migration. K. Nam1,2,3, P. Kim1, D.K. Wood4, S. Kwon2,5,6, P. Provenzano4,7, D. Kim1; 1Department of Bioengineering, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, 2Department Electrical Computer Engineering, Seoul National University, Seoul, Korea, 3 Division of Scientific Instrumentation, Optical Instrumentation Development Team, The Korea Basic Science Institute, Daejeon, Korea, 4Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, 5Institutes of Entrepreneurial BioConvergence, Seoul National University, Seoul, Korea, 6Seoul National University Hospital Biomedical Research Institute, Seoul National University, Seoul, Korea, 7Masonic Cancer Center, and Stem Cell Institute, University of Minnesota, Minneapolis, MN B1221/P2260 The dynamic mechanical adaptation of keratocytes squeezed on 2D micropatterns. D. Mohammed1, G. Charras2, S. Gabriele1; 1Mechanobilogy Soft Matter Group, University of Mons, Mons, Belgium, 2London Centre of Nanotechnology, University College London, London, United Kingdom B1222/P2261 Displacement correlations between a single cell and its nucleus effectively link subcellular activities and motility in cell migration analysis. T. Lan1, X. Su1, Y. Tseng1,2,3; 1Chemical Engineering Department, Gainesville, FL, 2Institute of Cell Tissue Science and Engineering, Gainesville, FL, 33National Cancer InstitutePhysical Science Oncology Center, Gainesville, FL

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1223/P2262 MCAK contributes to cell migration by promoting MTOC reorientation. H. Zong1, C. Moe1, Y. Kim2, W. Wang3, C.E. Walczak3; 1Biology, Indiana University, Bloomington, IN, 2IU-ISURP Program, Indiana University, Bloomington, IN, 3Medical Sciences, Indiana University, Bloomington, IN B1224/P2263 The role of MMPs in collective cell migration of zebrafish keratocytes. M.A. Jeffery1, C.K. Uppalapati2, E.L. McGee3, A.S. Pascual1, M.R. Montgomery1, K.E. Cooper1, E.E. Hull1, K.J. Leyva2; 1Biomedical Sciences, College of Health Sciences, Midwestern University, Glendale, AZ, 2Microbiology Immunology, Arizona College of Osteopathic Medicine, Midwestern University, Glendale, AZ, 3 College of Veterinary Medicine, Midwestern University, Glendale, AZ B1225/P2264 Quantification of macrophage protrusion dynamics with in vivo light sheet microscopy. M. Albert1, N. Norlin1, F. Peri1; 1Developmental Biology, European Molecular Biology Laboratory, Heidelberg, Germany B1226/P2265 Mitomycin C treatment alters epithelial cell migration. M. Stepp1, V. Lieberman 1,2, G. Tadvalkar1, S. Pal-Ghosh1; 1Anatomy and Regenerative Biology, GWU Medical School, Washington, DC, 2Department of Biology, GWU, Washington, DC

Cell-Cell Junctions 2

B1229/P2267 Transcriptional control of desmosomal gene expression in breast and skin cancer cells. L. Eldredge1, A.D. Dubash1, J. Decker1; 1Biology, Furman University, Greenville, SC B1230/P2268 Regulation of cell-cell adhesions by I-BAR domain proteins. Y. Senju1, H. Vihinen1, M. Varjosalo1, J. Saarikangas1, E. Jokitalo1, P. Lappalainen1; 1Institute of Biotechnology, University of Helsinki, Helsinki, Finland B1231/P2269 Totaliter aliter: In the molecular architecture of its cytoskeleton and junctions the seminiferous epithelium of mammalian testes differs fundamentally from all other epithelia. L.M. Domke1, W.W. Franke1; 1Helmholtz Group for Cell Biology, German Cancer Research Center, Heidelberg, Germany B1232/P2270 Comprehensive analysis of formin localization at cell-cell junctions and cytokinetic contractile rings in epithelial cells. T. Higashi1, A.L. Miller1; 1MCDB, University of Michigan, Ann Arbor, MI

B1233/P2271 SUMO-modification alters intracellular localization of ZO-2. F. Wetzel1, S. Mittag1, M. CanoCortina2, T. Wagner3, O. Krämer4, R. Niedenthal5, L. Gonzalez-Mariscal2, O. Huber1; 1Biochemistry, Jena University Hospital, Jena, Germany, 2Physiology, Biophysics and Neuroscience, Cinvestav, Mexico City, Mexico, 3Center for Molecular Biomedicine, Jena, Germany, 4Toxicology, University Medical Center Mainz, Mainz, Germany, 5Institute of Physiological Chemistry/Biochemistry, Hannover Medical School, Hannover, Germany B1234/P2272 Pannexin 1 regulates adipocyte development and fat accumulation. V.R. Lee1, K.J. Barr1, J.J. Kelly1, D. Johnston1, C.F. Brown1, K.P. Robb2, R. Gros3,4, L.E. Flynn1,2, S. Penuela1; 1Anatomy and Cell Biology, University of Western Ontario, London, ON, 2 Chemical and Biochemical Engineering, University of Western Ontario, London, ON, 3 Physiology and Pharmacology, University of Western Ontario, London, ON, 4Robarts Research Institute, University of Western Ontario, London, ON B1235/P2273 A Sight For Injured Eyes: Role of Purinoreceptor-Mediated Calcium Oscillations. Y.K. Lee1, V. TrinkausRandall1; 1Biochemistry, Boston University School of Medicine, Boston, MA B1236/P2274 STIM/Orai colocalize at the periphery of apical processes in the seminiferous epithelium. K. Lyon1, A. Vogl2; 1Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, 2Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC B1237/P2275 Resolvin D1 protects endothelial barrier function from LPSinduced disruption via inhibition of xanthine oxidase-mediated reactive oxygen species production and SHP2 activation. R. Chattopadhyay1, G.N. Rao1; 1Physiology, University of Tennessee Health Science Center, Memphis, TN B1238/P2276 Sertoli Cell-Specific Knockout of Coxsackievirus and Adenovirus Receptor (Cxadr) Impairs Spermatogenesis. K. Huang1, S. Chow1, B. Ru1, J. Zhang1, W. Lui1; 1School of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong B1239/P2277 Galnt3 glycosylates key substrates essential for epithelial maintenance in trophoblast stem cells. D. Raghu1, A.N. Abell1; 1Biological Sciences, University of Memphis, Memphis, TN B1240/P2278 The Cell Wall Integrity pathway regulates cell wall degradation during S. cerevisiae mating. A.E. Hall1, M.D. Rose1; 1Molecular Biology, Princeton University, Princeton, NJ

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1241/P2279 Claudin-11, Occludin, Vimentin and Keratin-7 expression at the blood-testis barrier in rat testis: An immunohistochemical study. M. Barwig1, A. Blaschitz1, H. Hutter1, G. Dohr1; 1Institute for Cell Biology, Histology and Embryology, Medical University of Graz, Graz, Austria B1242/P2280 Super resolution mapping of membrane molecule organization and dynamics in confined cellular environments using monomeric streptavidin. I. Chamma1,2, M. Letellier2, C. Butler2,3, O. Rossier2, D. Choquet2,4, J. Sibarita2, G. Giannone2, S. Park5, M. Sainlos2, O. Thoumine2; 1University of Bordeaux, 33077, France, 2UMR 5297, Interdisciplinary Institute for Neuroscience, CNRS, 33077, France, 3 Imagine Optic, 91400, France, 4UMS 3420, Bordeaux Imaging Center, CNRS, 33077, France, 5 Department of Chemical and Biological Engineering, University at Buffalo, 14260, NY B1243/P2281 β-catenin is a pH sensor with decreased stability at higher pH. K.A. White1, B. Grillo-Hill2, M. Esquivel1, D.L. Barber1; 1Cell and Tissue Biology, University of California San Francisco, San Francisco, CA, 2Biological Sciences, San Jose State University, San Jose, CA B1244/P2282 Cx46 hemichannel inhibition induced by carbon monoxide, possible participation of lipid peroxides. M.A. Retamal1; 1Centro de Fisiología Celular e Integrativa, Univeridad del Desarrollo, Santiago, Chile B1245/P2283 Desmoplakin’s Regulation of Gap Junction Dynamics in Cardiocutaneous Model Systems. C.Y. Kam1, A.D. Dubash2, F. Sheikh3, P.D. Lampe4, K.J. Green1,5; 1Department of Pathology, Northwestern University, Chicago, IL, 2Department of Biology, Furman University, Greenville, SC, 3Department of Medicine, University of California-San Diego, La Jolla, CA, 4Translational Research Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 5Department of Dermatology, Northwestern University, Chicago, IL

Bioengineering of Cell-Matrix Interactions B1246/P2284 Emergence of supracellular boundaries on stiffness gradients. R. Sunyer1,2, P. Roca-Cusachs1,2,3, X. Trepat1,2,3,4; 1CIBER-BBN, Madrid, Spain, 2 IBEC, Barcelona, Spain, 3Departament de Ciències Fisiològiques I, University of Barcelona, Barcelona, Spain, 4Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

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B1228/P2266 A Novel Role for SNARE Proteins in Cardiac Desmosomal Biology and Disease. J. Pellman1, R.C. Lyon1, Y. Liang1, V. Mezzano1, F. Zanella1, J. Zhang1, Y. Gu1, N. Dalton1, K.L. Peterson1, F. Sheikh1; 1Department of Medicine, University of California-San Diego, La Jolla, CA

Tuesday Poster Session

Board No./Presentation No. B1247/P2285 Synergistic Effects of Matrix Nanotopography and Stiffness on Vascular Smooth Muscle Cell Function. S. Chaterji1, P. Kim2, S.H. Choe1, J.H. Tsui2, C.H. Lam1, D.S. Ho1, A.B. Baker1, D. Kim2,3,4; 1Biomedical Engineering, Cockrell School of Engineering, University of Texas, Austin, TX, 2Bioengineering, University of Washington, Seattle, WA, 3Center for Cardiovascular Biology, University of Washington, Seattle, WA, 4Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA B1248/P2286 Interplay between matrix topography and stiffness in the regulation of endothelial cytokines and chemokine secretion. H. Jeon1, J.H. Tsui2, S. Jang1, J.H. Lee2, S. Park1, K. Mun2, Y. Boo1, D. Kim2,3; 1Molecular Medicine, School of Medicine and Cell and Matrix Research Institute, Kyungpook National University, Daegu, Korea, 2Bioengineering, University of Washington, Seattle, WA, 3Institute for Stem Cell and Regenerative Medicine and Center for Cardiovascular Biology, University of Washington, Seattle, WA B1249/P2287 Single-cell and collective geometry sensing of biomaterial surfaces with micron-scale, smoothly curved topologies. P. Rougerie1, L. Pieuchot2, B. Pontes3, F. de Sá1, N. Sgambato1, M. Bigerelle4, N. Bessa Viana3, K. Anselme2, M. Farina de Souza1; 1Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, 2Institut de Science des Materiaux de Mulhouse, Universite de Haute Alsace, Mulhouse, France, 3Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, 4Departement de Mecanique, Universite de Valenciennes et du Hainaut Cambresis, Valenciennes, France B1250/P2288 Differential collective and single cell behaviors on silicon micropillar arrays. Z. Jahed1, R. Zareian1, Y. Chau2, B. Seo3, M. West1, T. Tsui3, W. Wen2, M. Mofrad1; 1Bioengineering, University of California Berkeley, Berkeley, CA, 2Department of Physics, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, 3Department of Chemical Engineering, University of Waterloo, Waterloo, ON B1251/P2289 Signal mingle: Micropatterns of BMP-2 and fibronectin on soft biopolymeric films regulate myoblast shape and SMAD signaling. V. Fitzpatrick1, L. Fourel2, O. Destaing2, F. Gilde1, C. Albiges-Rizo2, C. Picart1, T. Boudou1; 1LMGP (Laboratoire des Matériaux et du Génie Physique), Grenoble, France, 2IAB (Institut Albert Bonniot), Grenoble, France B1252/P2290 Microprinted neuronal networks as an efficient platform for studying the role of cytokines on neuronal plasticity. J. Lantoine1, L. Ris2, S. Gabriele1; 1Mechanobiology and Soft Matter Group-InFluX, UMons, Mons, Belgium, 2 Département de Neuroscience, UMons, Mons, Belgium

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Tuesday Poster Session B1253/P2291 Fibronectin derived RGD and PRARI peptides conjugated chitosan matrix promotes cell adhesion and neurite outgrowth through integrin α4β1, α5β1, αvβ3, and syndecan. K. Hozumi1, K. Nakamura1, H. Hori1, M. Miyagi1, R. Nagao1, F. Katagiri1, Y. Kikkawa1, M. Nomizu1; 1Laboratory of Clinical Biochemistry, Tokyo Univ Pharm and Life Sci, Hachioji, Japan B1254/P2292 3D spatial rearrangement of gingival fibroblast spheroids affected by collagen1 and fibrin hydrogels and nanofibers. G. Kaufman1, R. Whitescarver1, L. Nunes1, A. Eftimiades1, W. Tutak1; 1Volpe Research Center, ADA Foundation, Gaithersburg, MD B1255/P2293 Cardiac tissue bioengineering: studying the interface between extracellular matrix and stem cell-derived cardiomyocytes. C. Hochman-Mendez1, B.d. Mendes1, D.B. Campos1, A.B. Carvalho1, A.C. Carvalho1; 1Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

B1260/P2298 Collective cell polarization and arrangement on patterned substrate. B. Ji1; 1Department of Applied Mechanics, Beijing Institute of Technology, Beijing, China B1261/P2299 The roles of biomimetic material-mediated cell-matrix interaction in redifferentiation of chondrocytes. Y. Kim1,2, S.H. Kim3, Y. Hwang1,2; 1Department of integrated Biomedical Science, Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Korea, South, 2Institute of Tissue Regeneration, College of Medicine, Soonchunhyang University, Cheonan-si, Korea, South, 3Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea, South

Regulation of Aging

B1256/P2294 Effects of the extracellular matrix from failing human hearts on cardiac stem cell phenotypes. D.A. Delfin1, E.N. McKown1, J.L. DeAguero1; 1Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM

B1263/P2300 Age-dependent microenvironmental cues regulate epithelial lineage fidelity in human breast. M. Miyano1,2, M. Stoiber2, R. Sayaman2, C. Lin2, M. Stampfer2, J.B. Brown2, M.A. LaBarge1,2; 1Population Sciences, City of Hope, Duarte, CA, 2Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA

B1257/P2295 Glaucomatous extracellular matrix modulates normal trabecular meshwork cell responses. V. Raghunathan1,2, C.J. Murphy3,4; 1Department of Basic Sciences, College of Optometry, University of Houston, Houston, TX, 2 The Ocular Surface Institute, University of Houston, Houston, TX, 3Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, CA, 4Department of Ophthalmology, School of Medicine, University of California Davis, Davis, CA

B1264/P2301 Skin improvement by eggshell membrane associating with in vivo-epidermal moisture keeping and -dermal elasticity links to niche environment for skin cells with slow proliferation but good metabolism. Y. Atomi1, M. Shimizu1, E. Fujita1, M. Kurimoto1, S. Sano1, K. Yoshimura2, Y. Hasebe3; 1Material Health Science, Tokyo Univ Agriculture and Technology, Tokyo, Japan, 2Plastic Surgery, Jichi Medical University, Tochigi, Japan, 3Almado Inc., Tokyo, Japan

B1258/P2296 Cytoskeletal stabilityenhancing effects of hyaluronic acid on in vitro cultured endometrial stromal cells potentiates the regeneration of damaged uterine endometrium. Y. Kim1, S. Ku2, Y. Kim2, B. Kang3, H. Liu4; 1Department of Obstetrics and Gynecology, Korea University Medical College, Seoul, Korea, South, 2Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea, South, 3 Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea, South, 4Weill Cornell Medical College, Center for Reproductive Medicine and Infertility, Seoul, United States

B1265/P2302 Combined exposure to UVA1 and Polycyclic Aromatic Hydrocarbons impairs redox homeostasis in human keratinocytes. J. Soeur1, J. Belaidi1, C. Chollet1, L. Denat1, A. Dimitrov1, C. Jones1, P. Perez1, M. Zanini1, O. Zobiri1, S. Mezzache1, D. Erdmann1, J. Eilstein1, G. Lereaux1, L. Marrot1; 1Advanced Research, L’Oreal, Aulnay-sous-Bois, France

B1259/P2297 Invasion pattern analysis of oral cancer cells In Vitro. E. Hoque Apu1, .U. Akram2, M. Sutinen1, L. Eklund3, T. Salo1; 1Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland, 2Computer Science and Engineering, University of Oulu, Oulu, Finland, 3Biocenter Oulu, University of Oulu, Oulu, Finland

B1266/P2303 Analysis of mitochondrial dysfunction in Hutchinson-Gilford Progeria Syndrome. I.A. Garcia-Aguirre1, B. Cisneros-Vega1; 1Departament of Genetic and Molecular Biology, CINVESTAV, Mexico City, Mexico B1267/P2304 Effect of the aging on the relationships between the visceral fat area and the CBC, including lymphocyte fraction and red blood cell numbers. Y. Kawata1, T. Kada1, M. Koyoshi1, T. Nakano1, M. Kawamura1, N. Okamoto1, Y. Hirotsu1, J. Kawata2; 1Department of Medicine, Saiseikai Toyoura Hospital, Shimonoseki, Japan, 2 Internal Medicine, Kawata Junko Clinic, Shimonoseki, Japan

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1268/P2305 Screening for MicroRNAs Influencing Double-strand Break Repair Choice. Y. Chen1, Z. Liu1, Z. Mao1; 1School of Life Sciences and Technology, Tongji University, Shanghai, China B1269/P2306 An alternative approach to studying chronological aging in yeast Saccharomyces cerevisiae. M. BialeckaFornal1, S.M. Rafelski1; 1Developmental and Cell Biology, University of California, Irvine, Irvine, CA B1270/P2307 Aged blood factors decrease cellular responses associated to gingival wound healing. M. Caceres Lluch1, A. Morgan1, C. Diaz1, A. Silva1, M. Saldias1, C. Fernandez1, F. Briceño1, O. Cerda1; 1Program of Molecular and Cell Biology. ICBM, Universidad de Chile, Santiago, Chile B1271/P2308 Antiproliferative and Proapoptotic Activity of the Goniothalamin in Prostatic Microenvironment from Senile Mice. L.A. Kido 1, F. Montico1, D.B. Vendramini-Costa2, V.H. Cagnon1, R.A. Pilli2; 1Structural and Funcional Biology, University of Campinas, Campinas, Brazil, 2Department of Organic Chemistry- Institute of Chemistry, University of Campinas, Campinas, Brazil B1272/P2309 NOX4 Inhibit the eNOS Protein folding With Aging. H.A. Zeeshan1, H.Y. Lee1, A. Noureen2, H.R. Kim3, H.J. Chae1; 1Pharmacology, Chonbuk National University, Jeonju, Korea, South, 2Burjeel Medical Centre, Al-Shamkha, Abu Dhabi, United Arab Emirates, 3 Graduate School, DGIST, daegu, Korea, South

Autophagy B1274/P2311 VCP-Dependent Muscle Degeneration is Linked to Defects in a Dynamic Tubular Lysosomal Network in vivo. A.E. Johnson1, H. Shu1, A. Hauswirth1, A. Tong1, G.W. Davis1; 1Biochemistry and Biophysics, UCSF, San Francisco, CA B1275/P2312 Establishment of a novel lysosomal integrity assay. E. Itakura1, A. Matsuura1; 1Graduate School of Advanced Integration Science, Chiba University, Chiba, Japan B1276/P2313 Understanding the relationship between ubiquitinated proteins and constitutive autophagy. K. Takayama1, A. Matsuura1, E. Itakura1; 1Graduate School of Advanced Integration Science, Chiba University, Chiba, Japan

B1277/P2314 Autophagy and ubiquitin proteasome pathway feedback stimulation in corneal epithelial cells with limbal stem cell deficiency. F. Bardag-Gorce1, R.H. Hoft1, A. Laporte1, A. Makalinao1, J.P. Stark1, Y. Niihara1; 1Pathology, LA BioMed, Torrance, CA B1278/P2315 Loss of autophagy receptors reveals roles in the maintenance of cellular proteostasis and clearance of aggregation prone proteins. S.A. Sarraf1, H.V. Shah1, C. Wang1, R.J. Youle1; 1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD B1279/P2316 Role of the human Vps15 kinase in PI3K complex I mediated autophagy regulation. G. Stjepanovic1,2, M.G. Lin1, S. Baskaran1, L. Carlson1, J.H. Hurley1,2; 1MCB, UC Berkeley, Berkeley, CA, 2 LBNL, Berkeley, CA B1280/P2317 Study of termination mechanism of autophagy under prolonged starvation. S. Kira1, M. Noguchi2, T. Noda1,2; 1Grad Sch Dentistry, Osaka University, Osaka, Japan, 2Grad Sch Frontier Biosicence, Osaka University, Osaka, Japan B1281/P2318 Autophagy regulates myelin compaction in the final stages of CNS myelination. A.N. Bankston1,2, M.D. Forston2,3, A.M. Smith1,2, R.M. Howard1,2, S.R. Whittemore1,2; 1Department of Neurological Surgery, University of Louisville, Louisville, KY, 2Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, KY, 3Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY B1282/P2319 Ribosome profiling uncovers that autophagy instructs the translation of proteins involved in cell cycle control and centrosome maintenance. J. Goldsmith1, S. Asthana2, H. Huang3, A. Xu1, A. Olshen2, A. Wiita3, J. Debnath1; 1Pathology, UCSF, San Francisco, CA, 2Department of Medicine, UCSF, San Francisco, CA, 3Laboratory Medicine, UCSF, San Francisco, CA B1283/P2320 The role of cancer-associated protein survivin in autophagy. N. Humphry1, S.P. Wheatley1; 1Life Science, University of Nottingham, Nottingham, United Kingdom B1284/P2321 The nuclear splicing factor Acinus moonlights as a cytosolic activator of autophagy. N. Nandi1, L.K. Tyra1, H. Kramer1; 1Dept. of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX B1285/P2322 α-Tubulin Acetylation as a Key Modification for Plant Autophagy Development. V. Fedyna1, D.I. Lytvyn1, A.I. Yemets1, Y.B. Blume1; 1Dept. Genomics and Molecular Biotechnology, Institute of Food Biotechnology and Genomics, Kiev, Ukraine

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1286/P2323 Visualizing the architecture and dynamics of the phagophore assembly site. M.G. Lin1, J. Schoeneberg 1 1 ;  Molecular and Cell Biology, UC Berkeley, Berkeley, CA B1287/P2324 Atg12 maintains skeletal integrity by modulating pro-osteoclastogenic signals and chondrocyte differentiation. C.G. Tahimic1,2, Y. Shirazi-fard1,2, T. Marsh3, A. Schreurs1, V.E. Rael4,5, C. Glikbarg1, J. Debnath3, R.K. Globus1; 1Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 2Wyle Laboratories, Moffett Field, CA, 3School of Medicine, Department of Pathology, University of California at San Francisco, San Francisco, CA, 4Space Life Sciences Training Program (SLSTP), NASA Ames Research Center, Moffett Field, CA, 5Biological Sciences Collegiate Division, University of Chicago, Chicago, IL B1288/P2325 Mitochondrial Fusion Is Required for Atg14p Redistribution onto the Vacuole Membrane to Trigger LD Autophagy upon Glucose Restriction. A.Y. Seo1, M.A. Le Gros2, C.A. Larabell2, J. Lippincott-Schwartz1; 1Janelia Research Campus, HHMI, Ashburn, VA, 2Anatomy, University of California San Francisco, San Francisco, CA B1289/P2326 mTORC1-regulated lipid droplet biogenesis maintains cellular energy homeostasis during starvation. T. Nguyen1, Q. Tran1, R. Perera2, R. Zoncu3, J.A. Olzmann1; 1Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA, 2Anatomy, University of California, San Francisco, San Francisco, CA, 3Molecular and Cellular Biology, University of California, Berkeley, Berkeley, CA B1300/P2327 IPMK promotes AMPK dependent ULK phosphorylation critical for autophagy activation. P. Guha1, S.H. Snyder1; 1Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD B1301/P2328 Beclin1 phosphorylation by Death-associated protein kinase1 contributes to autophagy activation by globular adiponectin in RAW 264.7 macrophages. N. Tilija Pun1, P. Raut1, E. Kim1, A. Khakurel1, H. Oh1, A. Shrestha1, P. Park1; 1College of Pharmacy, Yeungnam University, Gyeongsan, Korea, South B1302/P2329 Dietary compound α-asarone ameliorates oxysterol-induced macrophage injury through beclin1-dependent autophagy. S. Park1, Y. Kang1; 1Department of Food Science and Nutrition, Hallym University, Chuncheon, Kangwon-do, Korea, South B1303/P2330 TBK1 activation in the PINK1PARKIN-mediated mitophagy. J. Heo1, J.A. Paulo1, J.W. Harper1; 1Cell Biology, Harvard Medical School, Boston, MA

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B1273/P2310 An important role of EGLN3 in epidermal regeneration and differentiation. S. Yoon1, A. Primorac1, M. Dumas2, R. Huggenberger1, C. Nizard2, S. Schnebert2, M. Detmar1; 1Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland, 2LVMH Recherche, Saint-Jean-de-Braye, France

Tuesday Poster Session

Board No./Presentation No. B1304/P2331 Autophagy machinery genes are differentially required for autophagy and Parkin-mediated mitophagy. C. Wang1, C. Nezich1, R.J. Youle1, C. Zhen2; 1SNB/NINDS, National Institutes of Health, Bethesda, MD, 2Department of Biochemistry, California Institute of Technology, Pasadena, CA B1305/P2332 Esm1p, a novel regulator of phospholipid imbalance-induced microlipophagy. E.J. Garcia1, J.D. Vevea1,2, L.A. Pon1; 1Department of Pathology and Cell Biology, Columbia University, New York, NY, 2Department of Neuroscience, University of Wisconsin, Madison, WI B1306/P2333 Impact of autophagy deletion on bone structure. D. Bahl1, Y. Shirazifard1, T. Marsh 2, A. Schreurs1, V.E. Rael3,4, C. Glikbarg1, J. Debnath2, R.K. Globus1, C.G. Tahimic1,5; 1Space Biosciences Division, NASA Ames Research Center, Mountain View, CA, 2Pathology, School of Medicine, University of California at San Francisco, San Francisco, CA, 3Space Life Sciences Training Program, NASA Ames Research Center, Mountain View, CA, 4 Biological Sciences Collegiate Division, University of Chicago, Chicago, IL, 5Wyle Laboratories, El Segundo, CA

Chemical Approaches to Cell Biology B1308/P2334 Graphene Based Binding Kinetics Assay for Real-Time Monitoring of Biological Signals in Complex Media. B.R. Goldsmith1, A. Walker1, D. Pan1, M. Lerner1, F.E. Barron1; 1Nanomedical Diagnostics, San Diego, CA B1309/P2335 Graphene Oxide-Incorporated PLGA/RGD Peptide Fiber Sheets for Vascular Smooth Muscle Regeneration. Y. Shin1, J. Han2, C. Kim2, W. Kim2, D. Han1, J. Oh3; 1Cogno-Mechatronics Engineering, Pusan National University, Busan, Korea, South, 2Nano Fusion Technology, Pusan National University, Busan, Korea, South, 3 Nano Energy Engineering, Pusan National University, Busan, Korea, South B1310/P2336 The phosphorylation of focal adhesion kinase in human dermal fibroblasts on chiral/racemic amyloid-like fibrils. F. Katagiri1, K. Mori1, K. Hozumi1, Y. Kikkawa1, M. Nomizu1; 1Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan B1311/P2337 Somatic Reprogramming Mediated by Mesoporous Silica Nanoparticle(MSN). Y. Liu1, F. Sun1, M. Wang1; 1School of Life Sciences and Technology, Tongji University, Shanghai, China

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Tuesday Poster Session B1312/P2338 Therapeutic application of taurine as a potential TRPV1 inhibitor. M. Moriuchi1, Y. Nakano2, Y. Tsurekawa1,3, M. Piruzyan1,3, M. Takada2, M. Morita2, M.A. Suico1, T. Shuto1, H. Kai1,3; 1Graduate school of Pharmaceutical Science, Kumamoto university, Kumamoto, Japan, 2 School of Pharmacy, Kumamoto university, Kumamoto, Japan, 3Health life science: Interdisciplinary and Glocal Oriented, Kumamoto university, Kumamoto, Japan B1313/P2339 Asymmetric mutations in a reengineered homodimer reveal multiple communication pathways in binding cooperativity. M. Lanfranco1, F. Garate1, A.J. Engdahl2, R.A. Maillard1; 1Chemistry, Georgetown University, Washington, DC, 2 University of Maryland School of Medicine, Baltimore, MD B1314/P2340 Inhibition of vascular leakage through inhibiting VEGF-induced transglutaminase activation in diabetic retina. Y. Lee1, H. Jeon1, K. Ha1; 1molecular and cellular biochemistry, kangwon national university school of medicine, chuncheon, Korea, South B1315/P2341 Regulation and synthesis of a putative iron-binding biocontrol pigment in the budding yeast Kluyveromyces lactis. S. Opara1, A. Cain1, A. LopezRivera1, L.A. Silveira1; 1Biology Department, University of Redlands, Redlands, CA B1316/P2342 Towards Understanding the Crystal Structure of Wild Type Phenylalanine Hydroxylase: The H₂O Count Discrepancy. O. Grosser1, J. Caradonna2; 1Biotechnology, Massachusetts Bay Community College, Wellesley, MA, 2 Chemistry, Boston University, Boston, MA

Embryogenesis 2 B1318/P2343 Implication of Importin-8 in mouse brain development. G. Nganou1, B. Coumans1, T. GRISAR1, L. Denijs2, B. Lakaye1; 1GIGA-Neurosciences, University of Liege, Liège, Belgium, 2MHeNs School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands B1319/P2344 Investigation of the molecular mechanisms underlying Reelin-induced neuronal aggregation in the mouse neocortex. S. Inoue1, K. Hayashi1, K. Kubo1, K. Nakajima1; 1Department of Anatomy, Keio University School of Medicine, Tokyo, Japan

B1322/P2347 SJJ1 deficiency leads to abnormal morphogenesis and embryonic lethality. T. Kim1, S. Jeon1, G. Oh1; 1Division of Life Science, Ewhah Womans University, Seoul, Korea, South B1323/P2348 Hypoxic Zebrafish and Inositol. S.D. Williams1, B. Sims1; 1Pediatrics, University of Alabama at Birmingham, Birmingham, AL B1324/P2349 Cell Size Regulated Zygotic Genome Activation. H. Chen1, L. Einstein1, M. Good1,2; 1Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA, 2Bioengineering, University of Pennsylvania, Philadelphia, PA B1325/P2350 CYK-4’s Role in Regulating CENP-A Maintenance in Chromosomes. C.A. Barnhardt1, E. Hughes1, L. Smith2, P.S. Maddox1; 1Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2 Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC B1326/P2351 Linking cell size and transcription in Xenopus egg and embryo extracts. L.C. Einstein1, M. Good1; 1Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA B1327/P2352 Regulation of brain development and neuronal function by protein arginylation. J. Wang1, N.A. Leu1, S. Sterling1, A.S. Kashina1; 1Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA B1328/P2353 Biophysical context shaping the emergence of animal multicellularity. B.T. Larson1, N. King2,3; 1Biophysics, UC Berkeley, Berkeley, CA, 2MCB, UC Berkeley, Berkeley, CA, 3HHMI, Berkeley, CA B1329/P2354 Chick cranial neural crest cells do not utilize contact inhibition of locomotion for migration. M. Genuth1, T. Mikawa1, O.D. Weiner1; 1Cardiovascular Research Institute, UCSF, San Francisco, CA B1330/P2355 Direct monitoring of nitric oxide levels show cardiogenic signaling in early staged chicken embryos. D. Shah1, W.F. Denetclaw1; 1Biology, San Francisco State University, San Francisco, CA

B1320/P2345 Deficiency of MNL1 Causes Pleiotropic Developmental Defects in Mice. H. Kweon1, M. Lee1, H. Noh1, G. Oh1; 1Division of Life Science, Ewha Womans University, Seoul, Korea, South B1321/P2346 Microtubule based nuclear spacing in the Drosophila syncytial embryo. O. Deshpande1, I.A. Telley1; 1IGC, Fundaçao Calouste Gulbenkian, Oeiras, Portugal

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No.

Cytoskeleton in Tissue Development and Morphogenesis B1331/P2356 Desmosomal cadherin association with a dynein-cortactin complex exerts temporal and spatial control over mechanical changes required for epidermal morphogenesis. O. Nekrasova1,2, R.M. Harmon3, J.A. Broussard1, J.L. Koetsier1, K.J. Green1,2; 1Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3 . Institute for Biophysical Dynamics, James Franck Institute and Department of Physics, The University of Chicago, Chicago, IL B1332/P2357 Dynamin regulates actin cytoskeletal organization during cellcell fusion. N. Gerassimov1, S. Kim1, A. Mercado-Perez1, T. Tran1, D. Luvsanjav1, E.H. Chen1; 1Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD B1333/P2358 Control of apico-basal epithelial polarity by the microtubule minus-end binding protein CAMSAP3 and spectraplakin ACF7. I. Noordstra1, Q. Liu1, W. Nijenhuis1, S. Hua1, K. Jiang1, M. Baars1, S. Remmelzwaal1, M. Martin1, L.C. Kapitein1, A. Akhmanova1; 1Cell Biology, Utrecht University, Utrecht, Netherlands

B1335/P2360 Asymmetrical distribution of actin and endocytic proteins in fusing myoblasts. Y. Liu1; 1Institute of Molecular Medicine, National Taiwan University, Taipei, Taiwan B1336/P2361 Possible functions of obscurin in non-muscle tissue. A. Katzemich1, F. Schöck1; 1Biology, McGill University, Montreal, QC B1337/P2362 A gain-of-function β tubulin mutation causes dendrite degeneration in C. elegans sensory neurons. X. Liang1, X. Wang1, K. Shen1,2; 1Institute of Biophysics, CAS, Beijing, China, 2Department of Biology, Howard Hughes Medical Institute, Stanford University, CA B1338/P2363 Orchestrated content release from Drosophila glue-protein vesicles by a contractile actomyosin network. D. Meyen1, T. Rousso1, E.D. Schejter1, B. Shilo1; 1Molecular Genetics, Weizmann Institute, Rehovot, Israel

B1339/P2364 Tissue-specific, acute MyosinII activity depletion dismisses current models of tissue force orchestration in dorsal closure. L. Pasakarnis1, E. Frei1, E. Caussinus1, M. Affolter2, D. Brunner1; 1Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland, 2Biozentrum, University of Basel, Basel, Switzerland B1340/P2365 The Physics of Blastoderm Flow during Early Gastrulation of Tribolium castaneum. S. Muenster1,2,3, A. Mietke3, A. Jain1, P. Tomancak1, S.W. Grill2,3; 1MPI-CBG, Dresden, Germany, 2 Biophysics, TU Dresden, Dresden, Germany, 3Biophysics, MPI-PKS, Dresden, Germany B1341/P2366 Myonuclear domains establishment during skeletal muscle fibers formation implicates SH3KBP1 activity. A. Guiraud1, N. Couturier1, C. Burny2, S. Janczarski2, V. Buchman3, V. Gache1; 1U1217/INMG/MNCA, INSERM, Lyon, France, 2UMR 5239, LBMC, ENS Lyon-CNRS, lyon, France, 3Cardiff University, School of Biosciences, Cardiff, United Kingdom B1342/P2367 Anillin regulates epithelial mechanics by structuring the apical actin network. T.R. Arnold1, R.E. Stephenson1, K.M. Dinshaw1, T. Higashi1, A.L. Miller1; 1Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI B1343/P2368 Identifying genetic players in cell sheet morphogenesis using a Drosophila deficiency screen for genes that contribute to dorsal closure. R.D. Mortensen1, S.M. Fogerson1, D.P. Kiehart1; 1Biology, Duke University, Durham, NC B1344/P2369 Boundary formation and maintenance during zebrafish neurodevelopment. A. Vichas1, C.B. Moens1; 1Basic Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA

Cell Fate Determination 2 B1345/P2370 Cdo regulates cell-surface expression and activity of Kir2.1 K+ channel in myogenic differentiation. Y. Leem1,2, H. Jeong1,2, H. Kim2,3, H. Cho2,3, J. Kang1,2; 1Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea, South, 2Samsung Biomedical Research Institute, Suwon, Korea, South, 3Department of Physiology, Sungkyunkwan University School of Medicine, Suwon, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1346/P2371 Desmin modulates Nkx2.5 expression in cardiac stem cells by entering the nucleus and participating in transcription factor complexes that interact with the nkx2.5 gene. C. Fuchs1, S. Gawlas1, P. Heher1, S. Nikouli2, H. Paar1, M. Ivankovic1, M. Schultheis1, J. Klammer1, T. Gottschamel1, Y. Capetanaki2, G. Weitzer1; 1Department of Medical Biochemistry, Max F. Perutz Laboratories, Vienna Biocenter, Medical University of Vienna, Vienna, Austria, 2Biomedical Research Foundation Academy of Athens, Athens, Greece B1347/P2372 Knocking out individual miRNA17 family members results in mis-expression of cardiac genes and cardiac defects. G.I. Gallicano1, Z. Zhang1, S. Mahapatra1, R. Ursin1; 1Biochemistry and Molecular Cellular Biology, Georgetown University Medical Center, Washington, DC B1348/P2373 Matrix tension directs human embryonic stem cell mesoderm and cardiomyocyte differentiation. L. Przybyla1, J.M. Muncie1,2, J.N. Lakins1, V.M. Weaver1,3,4,5,6; 1Surgery, UCSF, San Francisco, CA, 2Bioengineering, UC Berkeley, Berkeley, CA, 3Anatomy, UCSF, San Francisco, CA, 4Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA, 5 The Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA, 6 Bioengineering and Therapeutic Sciences, UCSF, San Francisco, CA B1349/P2374 The Role of Phosphatidylinositol Transfer proteins (PITPs) in Mouse Brain Development. S.K. HUR1, Z. Xie1, V.A. Bankaitis1; 1Department of Molecular and Cellular Medicine, Texas AM University Health Science Center, College Station, TX B1350/P2375 Role of Pumilio proteins during neural crest development. E. Kunttas-Tatli1, M.E. Bronner1; 1Biology and Biological Engineering, California Institute of Technology, Pasadena, CA B1351/P2376 RNF220 mediated K-63 linked ubiquitinagion induces sequestration of Gli to pattern the ventral neural tube. P. Ma1, N. Song2, Y. Ding2, B. Mao1; 1Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China, 2Medical School, Tongji University, Shanghai, China B1352/P2377 Satellite glial cells represent a population of arrested Schwann cell precursors. D. George1, P. Ahrens2, W. Anderson1, S. Lambert2; 1Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 2Department of Medical Education, University of Central Florida, Orlando, FL B1353/P2378 mTOR and PAK1 regulate oligodendrocyte differentiation through morphological differentiation and myelination. T. Brown1, L.T. Finseth1, W.B. Macklin1; 1Cell and Developmental Biology, University of Colorado AMC, Aurora, CO

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TUESDAY

B1334/P2359 Loss of Gα12/13 exacerbates apical area-dependence of actomyosin contractility. S. Xie1,2, F.M. Mason3, A. Martin3; 1Computational and Systems Biology PhD Program, MIT, Cambridge, MA, 2 Department of Biology, Stanford University, Stanford, CA, 3Department of Biology, MIT, Cambridge, MA

Tuesday Poster Session

Board No./Presentation No. B1354/P2379 actr10 regulates trafficking of mbp mRNA in oligodendrocytes to promote proper myelination of the central nervous system. A.L. Herbert1, M. Fu2, C. Drerup3, B. Harty1, S. Ackerman1, R. Gray4, T. O Reilly Pol5, S. Johnson1, A. Nechiporuk3, B. Barres2, K.R. Monk1; 1Developmental Biology, Washington University School of Medicine, St. Louis, MO, 2Neurobiology, Stanford University School of Medicine, Stanford, CA, 3Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, 4Pediatrics, University of Texas Dell Medical School, Austin, TX, 5Genetics, Washington University School of Medicine, St. Louis, MO B1355/P2380 Cross talk between microglia and astrocyte promote proliferation and M2-polarization of microglia. S. Kim1, J. Lim1, W. Ahn1, M. Zhang1, E. Chung1, Y. Son1; 1Life science, Kyung Hee University, Yongin-si, Korea, South B1356/P2381 Postnatal development and age- and region-dependent diversity of glial GLAST-positive cells. I.N. Dominova1, O.P. Tuchina1, L. Klimaviciusa1, N.A. Filiakova1, A.A. Vasilev1, M.V. Patrushev1, V.A. Kasymov1; 1Department of Neurobiology and Medical Physics, Immanuel Kant Baltic Federal University, Kaliningrad, Russia

Stem Cells and Pluripotency B1357/P2382 The molecular basis for the deficiency of innate immunity in mouse embryonic stem cells and their differentiated cells. Y. Guo1, W. DAngelo1, C. Gurug1, D. Acharya1, B. Chen1, N. Ortolano1; 1Department of Biological Sciences, The University of Southern Mississippi, Hattiesburg, MS B1358/P2383 Dicer-1 regulates proliferative potential of Drosophila larval neural stem cells through bantam miRNA dependent downregulation of the G1/S inhibitor Dacapo. A. Banerjee1, J.K. Roy1; 1Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India B1359/P2384 Characterization of ESC-differentiated fibroblasts with mesenchymal stem cell properties. W.A. D’Angelo1, D. Acharya1, C. Gurung1, Y. Guo1; 1Department of Biological Sciences, The University of Southern Mississippi, Hattiesburg, MS B1360/P2385 A key role for occluding junctions in regulating the hematopoietic stem cell microenvironment to trigger immune activation in Drosophila. R. Khadilkar1, G. Tanentzapf1, A. Vogl1; 1Cellular& Physiological Sciences, The University of British Columbia, Vancouver, BC

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Tuesday Poster Session B1361/P2386 Transcriptional regulation of Drosophila intestinal stem cells. D.P. Doupe1, O.J. Marshall2,3, A.H. Brand2,3, N. Perrimon1,4; 1Genetics, Harvard Medical School, Boston, MA, 2Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom, 3 The Gurdon Institute, Cambridge, United Kingdom, 4Howard Hughes Medical Institute, Boston, MA B1362/P2387 Role of the mitochondrial pyruvate carrier in transcriptional reprogramming of intestinal stem cells. J.M. Tanner1, J. Rutter1; 1Biochemistry, University of Utah School of Medicine, Salt Lake City, UT B1363/P2388 Novel insights into the molecular mechanisms of transdifferentiation of cells into brown adipose tissue-like cells. S.R. Taylor1, E. Miller1, C.A. Gemma1, D.C. Pfeil1, P.A. Harding1; 1Biology, Miami University, Oxford, OH B1364/P2389 Regulation of stem cell repopulation in the planarian Schmidtea mediterranea. K. Lei1, H.T. Vu1, R.D. Mohan2, S. McKinney1, C. Seidel1, R. Alexander1, K. Gotting1, J.L. Workman1, A. Sánchez Alvarado1,3; 1Stowers Institute for Medical Research, Kansas City, MO, 2 School of Biological Sciences, Division of Cell Biology and Biophysics, University of Missouri - Kansas City, Kansas City, MO, 3 Howard Hughes Medical Institute, Kansas City, MO B1365/P2390 Mitochondrial networking and mitophagy in human pluripotent stem cells. S.E. Krantz1, M. Rexius-Hall1, L. Wang1, P. Toth1, G. Marsboom1, J. Rehman1; 1Medicine and Pharmacology, University of Illinois at Chicago, Chicago, IL B1366/P2391 The Role of KDF1 and IKKα in Keratinocyte Differentiation. Y. Li1, X. Gou1, J. Yue1, P. Lee1, X. Wu1; 1The Ben May Department for Cancer Research, the University of Chicago, Chicago, IL B1367/P2392 Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. H. Nakano1,2, I. Minami3, D. Braas4, H. Pappoe1, X. Wu5, A. Sagadevan1, L. Vergnes6, K. Fu1, M. Morselli1, X. Ding7, A.Z. Stieg8, J.K. Gimzewski7,8,9, M. Pellegrini1, P.M. Clark4,9,10, K. Reue6,11, A. Lusis5,6,11,12, B. Ribalet13, S. Kurdistani2,9,11,14, H. Christofk2,4,11,14, N. Nakatsuji3, A. Nakano1,2,9,11; 1Departmemt of Molecular Cell Developmental Biology, University of California, Los Angeles, Los Angeles, CA, 2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, 3Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto, Japan, 4Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 5Department of Medicine, University of California, Los Angeles, Los

Angeles, CA, 6Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, 7Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 8 California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, 9Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, 10Crump Institute for Molecular Imaging, University of California, Los Angeles, Los Angeles, CA, 11Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 12Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 13Department of Physiology, University of California, Los Angeles, Los Angeles, CA, 14Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA B1368/P2393 RBM8a regulates neural progenitor proliferation. C. McSweeney1, D. Zou1, A. Sebastian 1, I. Albert1, Y. Mao1; 1Biology, Penn State University, State College, PA B1369/P2394 The translational landscape during human neuronal differentiation at transcript isoform resolution. S.N. Floor1,2, J. Blair1, H. Bateup1, D. Hockemeyer1, J.A. Doudna1,2; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Howard Hughes Medical Institute, Berkeley, CA B1370/P2395 Pigment Epithelium-Derived Factor (PEDF) Peptide Promotes the Expansion of Hepatic stem/Progenitor Cells via ERK and STAT3-Dependent Signaling. Y. Tsao1; 1Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan B1371/P2396 Pluripotent stem cell selfrenewal on a ligand-rich hydrogel matrix with tunable stiffness. A.J. Price1, E. Huang2, A.R. Dunn1,2; 1Biophysics, Stanford University, Stanford, CA, 2Chemical Engineering, Stanford University, Stanford, CA B1400/P2397 Regulating the cell fate specification of pluripotent stem cells. S. Chetty1; 1Psychiatry and Behavioral Sciences, and the Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA B1401/P2398 Fibroblast Growth Factor 2 enhances musculoskeletal differentiation potential of human adipose-derived stem cells. Y. Won1, S. Lim1, H. Cho1, E.K. Lee1, C. Kim1, E. Lee2, Y. Son1; 1Genetic Engineering, Kyung Hee University, Yongin, Korea, South, 2mpedance Imaging Research Center, Kyung Hee University, Seoul, Korea, South

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1402/P2399 Maternal fructose exposure impairs angiogenic activity of endothelial progenitor cells and reduces blood flow recovery after critical limb ischemia in rat offspring. S. Leu1, K.L. Wu1, Y. Tain1,2, W. Lee3, J.Y. Chan1; 1Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, 2Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, 3Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan B1403/P2400 Role of MARVELD1 in the reprogramming of mouse fibroblasts. Y. Chen1, H. Zhang1, F. Han1, Y. Li1; 1Harbin Institute of Technology, School of life science and technology, Harbin, China B1404/P2401 Stem cell self-renewal and clonal aging determine clone sizes and their fluctuations in granulopoiesis. T. Chou1, S. Xu1; 1Biomathematics, UCLA, Los Angeles, CA B1405/P2402 Dermal stem cells activation helps to promote skin elasticity. C. Nizard1, A. Lemestr2, c. Plaza2, C. Capallere2, R. Chabert2, I. Imbert2, J. Botto2, N. Garcia2, M. Dumas1, E. Leblanc1, S. Schnebert1, B. Bavouzet1, N. Domloge2; 1Life Science Department, LVMH Recherche, Saint jean de braye, France, 2Affiliate of Ashland Inc., Ashland Specialty Ingredient, Sophia-Antipolis, France

B1407/P2404 Low-level exposure to manganese disrupts morphology and intracellular signaling in cultured adult neural stem cells. A.S. Carpenter1, A. Ramirez1, A.B. Parsons-White1, N. Spitzer1; 1Biological Sciences, Marshall University, Huntington, WV B1408/P2405 Low-level silver nanoparticle exposure alters cytoskeletal dynamics via intracellular signaling pathways. B.N. Forren1, K.D. Brown1, R.J. Cooper1, M.N. Menking-Hoggatt1, N. Spitzer1; 1Biological Sciences, Marshall University, Huntington, WV B1409/P2406 Niche Regulation of Satellite Cell Quiescence by Classical Cadherins. A.J. Goel1, R.S. Krauss1; 1Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY

Host-Pathogen/HostCommensal Interactions 2 B1411/P2407 Biomechanical Alterations of Endothelial Cells Induced by Listeria monocytogenes. E.E. Bastounis1, J.A. Theriot1,2,3; 1Biochemistry, Stanford University, School of Medicine, Stanford, CA, 2Microbiology and Immunology, Stanford University, School of Medicine, Stanford, CA, 3Howard Hughes Medical Institute, Stanford University, School of Medicine, Stanford, CA B1412/P2408 Th bacterial pathogen Listeria monocytogenes exploits the human exocyst complex to promote cell-to-cell spread. G.C. Dowd1, K. Ireton1; 1Microbiology and Immunology, University of Otago, Dunedin, New Zealand B1413/P2409 Modeling Listeria monocytogenes cell-to-cell spread. F.E. Ortega1,2, E.F. Koslover3, J.A. Theriot1,2,4; 1Biochemistry, Stanford School of Medicine, Stanford, CA, 2Howard Hughes Medical Institute, Stanford, CA, 3Physics, University of California, San Diego, San Diego, CA, 4Microbiology and Immunology, Stanford School of Medicine, Stanford, CA B1414/P2410 Chlamydia trachomatis inclusion membrane protein CT192 interacts with dynactin to modulate centrosome positioning and parasitophorous vacuole fusion events. J. Sherry1, C. Elwell1, R. Bastidas2, M. Weber3, T. Hackstadt3, R.H. Valdivia2, J.N. Engel1,4; 1Department of Medicine, University of California, San Francisco, San Francisco, CA, 2Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, 3Host Parasite Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, 4Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA B1415/P2411 Molecular basis of the Chlamydia trachomatis effector IncE interaction with sorting nexin 5 to escape pathogen restriction. C. Elwell1, N. Czudnochowski1, K. Mirrashidi1, J. Johnson2,3, J. Von Dollen2,3, J. Sherry1, N. Krogan2,3,4, O. Rosenberg1, J. Engel1,5; 1Department of Medicine,, University of California, San Francisco, San Francisco, CA, 2California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA, 3Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 4Gladstone Institutes, University of California, San Francisco, San Francisco, CA, 5Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1416/P2412 Neisseria meningitidis type IV pili act as extracellular scaffolds for plasma membrane remodeling. A. Charles-Orszag1,2, M. Sachse3, J. KrijnseLocker3, G. Dumenil1; 1Pathogenesis of Vascular Infections Unit, INSERM, Pasteur Institute, Paris, France, 2Paris Descartes University, Paris, France, 3Ultrapole, Pasteur Institute, Paris, France B1417/P2413 Association of hypertension in mycobacteria-induced endoplasmic reticulum dysfunction. S. Cho1,2, J. Lee1,2, J. Choi1,2, S. Jo1,2, S. Oh1,2, S. Kim1,2, D. Go1,2, Y. Lim1,2, C. Song1,2; 1Department of Medical Science, Chungnam National University, College of Medicine, Daejeon, Korea, South, 2Department of Microbiology, Chungnam National University, College of Medicine, Daejeon, Korea, South B1418/P2414 A novel clan of cytotoxic leukocidins in Vibrios. A. Ray1,2, L. Kinch2, M. De Souza Santos1, N.V. Grishin2,3,4, K. Orth1,2,3, D. Salomon1; 1Molecular Biology, UT Southwestern Medical Center, Dallas, TX, 2Howard Hughes Medical Institute, UT Southwestern Medical Center, Dallas, TX, 3Biochemistry, UT Southwestern Medical Center, Dallas, TX, 4Biophysics, UT Southwestern Medical Center, Dallas, TX B1419/P2415 Investigating the effects of antifungals on Candida glabrata cell wall and cell membrane mutants. Y.Y. Chew1, H.C. Lin1, J.H. Gan1, C.F. Chin1, F.M. Yeong1; 1Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore B1420/P2416 Delivery of parasite RNA transcripts into infected epithelial cells during Cryptosporidium infection and its impact on host gene transcription. Y. Wang1, A. Gong1, S. Ma1, J. Chen1, J.K. Strauss-Soukup2, X. Chen1; 1Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE, 2Department of Chemistry, Creighton University College of Arts and Sciences, Omaha, NE B1421/P2417 Infection of macrophages with Cryptococcus neoformans alters inflammatory NF-κB signaling via translational interference. L.M. Sircy1, J.B. Hayes1, L.E. Heusinkveld1, K.D. Cunningham2, E.E. McClelland1, D.E. Nelson1; 1Department of Biology, Middle Tennessee State University, Murfreesboro, TN, 2Department of Chemistry, Middle Tennessee State University, Murfreesboro, TN B1422/P2418 Macrophage selenoproteins restrict intracellular replication of Francisella tularensis. R.L. Markley1, D.R. Williamson1, B. Katkere1, K.K. Dewan1, A.E. Shay1, B.A. Carlson2, K.S. Prabhu1, G.S. Kirimanjeswara1; 1The Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA, 2National Cancer Institute, National Institutes of Health, Bethesda, MD

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B1406/P2403 CD271 identifies an early keratinocyte stem cell progeny and modulates regenerative capacity in 3D reconstructed skin models. A. Marconi1, F. Truzzi1, R. Lotti1, M. Quadri1, E. Palazzo1, C. Nizard2, S. Schnebert2, M. Dumas2, C. Pincelli1; 1Laboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy, 2 Life Sciences, LVMH Recherche, Saint Jean De Braye, France

Tuesday Poster Session

Board No./Presentation No. B1423/P2419 The intracellular fungal pathogen Histoplamsa capsulatum alters phagosome maturation to survive within host macrophages. A.L. Cohen1, N. Van Prooyen1, M.C. Bassik2, A. Sil1; 1Microbiology and Immunology, University of California at San Francisco, San Francisco, CA, 2Genetics, Stanford University School of Medicine, Stanford, CA B1424/P2420 Interplay of the Microbiome and Innate Immune System in Tissue Regeneration. C.P. Arnold1, S. Merryman1, A. Harris-Arnold1, C. Seidel1, S. McKinney1, A. Sánchez Alvarado1; 1Stowers Institute of Medical Research, Kansas City, MO B1425/P2421 Invasion Dynamics in the Fly Gut Microbiota. B. Obadia1, T. Guvener1, V. Zhang1, W.B. Ludington1; 1Molecular Cell Biology, UC Berkeley, Berkeley, CA B1426/P2422 Functional multi ‘omics’ uncover a novel organelle with both prokaryotic and eukaryotic proteins that weaponizes parasites of Drosophila. M.E. Heavner1,2, J. Ramroop1, G. Ramrattan1, G. Dolios3, J. Crissman4, M. Scarpati5, J. Kwiat5, E.A. Miller6, W. Qiu1, R. Wang3, S. Singh2,5, S. Govind1,2; 1Biology, The City University of New York, New York, NY, 2Biochemistry, The Graduate Center of CUNY, New York, NY, 3Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 4Biological Sciences, Columbia University, New York, NY, 5Biology, The City University of New York, Brooklyn, NY, 6MRC Laboratory of Molecular Biology, Cambridge University, Cambridge, United Kingdom B1427/P2423 Direct visualization of phagocytes acting as Trojan horses and their contribution to brain invasion by the environmental yeast Cryptococcus neoformans. F.H. Santiago-Tirado1, M.D. Onken2, R.S. Klein3, J.A. Cooper2, T.L. Doering1; 1Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, 2Biochemistry Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, 3Medicine, Washington University School of Medicine, St. Louis, MO B1428/P2424 Toll-like receptor (TLR) expression profile and biological effects of selective TLR-ligands on stem cells from human exfoliated deciduous teeth. T. Chino1, R. Yu1, B.D. Zeitlin1; 1Biomedical Sciences, University of the Pacific Dugoni School of Dentistry, San Francisco, CA B1429/P2425 Novel human targets of L pneumophila effector protein AnkX identified by NAPPA protein arrays. B.P. Romero Duenas1, S.C. Allgood1, R.R. Noll1, X. Yu2, J. Qiu3, M. Machner4, J. LaBaer3, R. Neunuebel1; 1Biological Sciences, University of Delaware, Newark, DE, 2Beijing Proteome Research Center, National Center for Protein Sciences-Beijing, Beijing Institute of Radiation Medicine, Beijing, China, 3 Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, 4Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD

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Immune System B1431/P2426 TRIM72 regulates complement phagocytosis in alveolar macrophage via facultative recycling of CRIg. N. Nagre1, X. Cong1, C. Terrazas2, J.M. Schreiber1, A. Satoskar2, X. Zhao1; 1Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA, 2Departments of Pathology and Microbiology, Wexner Medical Center, The Ohio State University, Columbus, OH B1432/P2427 Assessing the Function of Pulmonary and Monocytic Cells upon Exposure to Ultrafine Black Carbon. M.E. Salinas1,2, K.M. Garza1; 1Biological Sciences, University of Texas- El Paso, El Paso, TX, 2Environmental Science Engineering, University of Texas- El Paso, El Paso, TX B1433/P2428 Regulation of Thymic Stromal Lymphopoietin Production by small molecule inhibitor as a therapeutic strategy to treat atopic dermatitis. H.E. Lee1, G. Yang1, J. Oh1, J. Lee1; 1College of Pharmacy, The Catholic University of Korea, Bucheon, Korea, South B1434/P2429 The immunosuppressive effect of mild electrical stimulation via NFAT pathway is a promising therapeutic approach for inflammation. M. Piruzyan1, M. Suico1, T. Shuto1, H. Kai1; 1Department of Molecular Medicine, Kumamoto University, Kumamoto, Japan B1435/P2430 Interleukin-22 supports osteoclast differentiation by stimulating COX-2-dependent RANKL production from osteoblast precursors. E. Lee1, H. Yang1, S. Kim1, B. Choi1, E. Kim1, K. Han1, J. Park1, M. Shin1, Y. Kim2, E. Chang1; 1Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, South, 2Department of Rheumatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, South B1436/P2431 Concomitant expression of microRNA218-2-3p and SLIT3 by toll-like receptor 4 stimulation inhibits osteoclastogenesis by directly suppressing RANK expression in osteoclast precursors. J. Park1, E. Kim1, E. Lee1, B. Choi1, S. Kim1, K. Han1, M. Shin1, H. Yang1, Y. Kim2, E. Chang1,3; 1Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Korea, South, 2 Department of Rheumatology, University of Ulsan College of Medicine, Seoul, Korea, South, 3Cell Dysfunction Research Center, Asan Medical Center, Seoul, Korea, South

B1437/P2432 Pentraxin 3 promotes atherosclerosis by inducing macrophage chemotaxis and adipogenesis through neuropeptide Y signaling. M. Shin1, B. Choi1, E. Lee1, S. Kim1, J. Park1, E. Kim1, K. Han1, H. Yang1, Y. Kim2, E. Chang1,3; 1Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Korea, South, 2Department of Rheumatology, University of Ulsan College of Medicine, Seoul, Korea, South, 3 Cell Dysfunction Research Center, Asan Medical Center, Seoul, Korea, South B1438/P2433 Anti-atopic effect of Artemisia capillaris extracts by solid-state fermentation of Ganoderma lucidum on a chemical-induced dermatitis model. H. Son1, S. Lee1, K. Kim1, W. Kim1, J. Heo2, J. Kim3, S. Lee1; 1Food Science and Biotechnology, Kyungpook National Univ., Daegu, Korea, South, 2Medical genomics, Keimyung Univ., Daegu, Korea, South, 3 FarmBios, Daegu, Korea, South B1439/P2434 The Role of Thymic Nurse Cells (TNCs) as an Intrathymic Source of Interleukin (IL-) 12 and Mediator of IL-12 Induced Apoptosis among Double Positive Thymocytes. S. Miller1, F. Davis2, S. Henley2, J. White2, M. Martinez3; 1Pathobiology, Tuskegee University, Tuskegee, AL, 2Integrative Biosciences, Tuskegee University, Tuskegee, AL, 3Biology, Tuskegee University, Tuskegee, AL B1440/P2435 Effects of minocycline against Propionibacterium acnesinduced inflammation in human keratinocytes. T. Sawant1, M. Hermsmeier1, D. Lac1, X. Chen1, A. Yamamoto1, Y. Huang1, K. Chan1, U. Nagavarapu1; 1BioPharmX, Inc., Menlo Park, CA B1441/P2436 Tracking Immune Cells After Tissue Damage Via X-Ray Irradiation in Manduca sexta, to Understand the Regenerative Ability of Insect Immune Cells. R. Bhaskar1; 1Biology, San Francisco State University, San Francisco, CA B1442/P2437 Tributyltin Alters Interleukin 1 beta and Interleukin 6 Production and mRNA expression from Human Immune Cells. S. Brown1, M. Boules1, N. Hamza2, M. Whalen2; 1Biological Sciences, Tennessee State University, Nashville, TN, 2Chemistry, Tennessee State University, Nashville, TN B1443/P2438 The Selective Serotonin Reuptake Inhibitor Fluoxetine Promotes Apoptosis in Neutrophil-Like HL-60 Cells. J. Daseke1, M.L. Petreaca1; 1Biology, DePauw University, Greencastle, IN B1444/P2439 Gamma-glutamyl transferase metabolizes LTC4 triggering cytokine release from macrophages. M.H. Hanigan1, N. Wakeham1; 1Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK B1445/P2440 Profiling of immunity biomarkers in whole blood. A.A. Chenchik1, A. Komarov1, M. Makhanov1, P. Diehl1, C. Frangou1; 1Cellecta, Inc., Mountain View, CA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Board No./Presentation No. B1446/P2441 Distribution of Dopamine Neurons in the Male Native Thai Chicken. Y. Chaiseha1, B. Kamkrathok1; 1School of Biology, Suranaree University of Technology, Nakhon Ratchasima, Thailand B1447/P2442 Immunohistochemical and hepatic gene expression changes in response to tacrolimus. T. Akhtar1, N. Sheikh1; 1Zoology, University of the Punjab, Q-A Campus, Lahore, Pakistan B1448/P2443 New ex vivo tests on human whole blood adapted to a global evaluation of the anti-inflammatory and immunomodulatory effects of ingredients. J. Franchi1, S. Schnebert1, K. Pays1, N. Amalric2; 1RD, LVMH RESEARCH, Saint Jean de Braye, France, 2Synelvia SAS, Labège, France B1449/P2444 Analysis of Fc gamma receptor function in CRISPR edited macrophages. J.G. Kerkvliet1, L.M. Martinez1, A.D. Hoppe1; 1Chemistry and Biochemistry, South Dakota State University, Brookings, SD B1450/P2445 Fast dynamics of FcγR microclusters during frustrated phagocytosis. S. Kurilova1,2, B.L. Scott1,2, A.D. Hoppe1,2; 1BioSNTR, South Dakota State University, Brookings, SD, 2Chemistry and Biochemistry, South Dakota State University, Brookings, SD

Defining Therapeutic Targets and New Therapeutics 2

B1452/P2447 ID1 and ID3 downstream transcription regulators in BMP4 signaling inhibits TGFβ2 induced fibrosis in TM cells. A.A. Mody1,2, A.F. Clark1,2, R.J. Wordinger1; 1Visual Science, University of North Texas Health Science Centre, Fort Worth, TX, 2North Texas Eye Research Institute, Fort Worth, TX B1453/P2448 Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new therapeutic candidates for osteoporosis. H. Kim1,2, S. Choi1,2, E. Ro1,2, K. Choi1,2; 1Department of Biotechnology, Yonsei University, Seoul, Korea, South, 2 Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea, South B1454/P2449 Ellagic acid and its promotion in osteoblast differentiation and bone mineralization. B. Santos1, B. Cabrera Vicens1, N. Gist1, A. Awuah1, J.Y. Belcher1; 1Science, Cabrini University, Radnor, PA

B1455/P2450 Study of adenosine deaminase acting on RNA (ADAR) isoforms towards genetic code restoration. A. Md Thoufic Anam1,2, S. Hitoshi2, T. Tsukahara2; 1Department of Veterinary and Animal Sciences, University of Rajshahi, Rajshahi, Bangladesh, 2School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa, Japan

B1462/P2457 High Content Analysis Identifies Kinetin in Restoration of a Function of Mutant Huntingtin Protein in Huntington’s Disease. L.E. Bowie1, T. Maiuri1, S. Patel1, M. Gabriel2, D.W. Litchfield2, S. Sipione3, R. Truant1; 1Biochemistry, McMaster University, Hamilton, ON, 2Biochemistry, Western University, London, ON, 3Pharmacology, University of Alberta, Edmonton, AB

B1456/P2451 Olesoxime orchestrates an interplay between mitochondria and microtubules that favors oligodendrocyte differentiation. K. Magalon1, M. Le Grand2, B. El Waly1, M. Moulis3, R.M. Pruss4, T. Bordet4, M. Cayre1, P. Belenguer3, M. Carré2, P. Durbec1; 1CNRS, IBDM, Aix-Marseille University, Marseille, France, 2INSERM, CRO2, Aix-Marseille University, Marseille, France, 3CNRS, CBD, Toulouse University, Toulouse, France, 4TROPHOS, Marseille, France

B1463/P2458 CRISPR/Cas9 GenomeWide gRNA Library for Target Identification. D. Tedesco1, P. Diehl1, M. Makhanov1, S. Baron1, C. Frangou1, A.A. Chenchik1; 1Cellecta, Inc., Mountain View, CA

B1457/P2452 Combination of Dehydroepiandrosterone plus triamcinolone acetonide inhibits the cell proliferation and induces morphological changes related to cell death in a fibroblast cell line. G. Gutierrez-Iglesias1, A. Parra-Barrera1, A.J. Sotelo-Camero1, N. Gutiérrez-Iglesias1, E. Mera-Jiménez1, J.R. Cáceres Cortés1, C.C. CalzadaMendoza1; 1Posgrado, Instituto Politécnico Nacional, Mexico City, Mexico B1458/P2453 c-Kit Mutation Prevents Cancellous Bone Loss during Calcium Deprivation in KitW-sh/W-sh Mice. S. Lotinun1,2, S. Poolthong3; 1Physiology and STAR on Craniofacial and Skeletal Disorders, Chulalongkorn University, Bangkok, Thailand, 2Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, 3Operative Dentistry, Chulalongkorn University, Bangkok, Thailand B1459/P2454 Modulation of acetaminophen-induced inflammasomes activation by globular adiponectin in rat primary hepatocytes. E. Kim1, N. Tilija Pun1, P. Raut1, A. Khakurel1, H. Oh1, A. Shrestha1, P. Park1; 1pharmacy, YeungNam University, GyeongSanSi, Korea, South B1460/P2455 Dietary compound chrysin inhibits neovascularization with increased formation of acellular capillaries in diabetic retina. M. Kang1, Y. Kang1, E. Lee1; 1Department of Food science and Nutrition, Hallym University, Chuncheon, Korea, South B1461/P2456 Trabecular meshwork stem cells regenerate laser-damaged TM tissue and reduce intraocular pressure. Y. Du1,2, H. Yun1, Y. Zhou1, J.S. Schuman3; 1Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 3NYU Langone Eye Center, New York University School of Medicine, New York, NY

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

B1464/P2459 Characterizing the source of immunoglobulins in prostate secretion. J.F. Silva1, M.F. Biancardi2, D.R. Stach-Machado1, H.F. Carvalho1, O.A. Sant’Anna3; 1Structural and Functional Biology, State University of Campinas, Campians, Brazil, 2Histology, Embryology and Cell Biology, Federal University of Goias, Goiania, Brazil, 3Immunochemistry, Butantan Institute, Sao Paulo, Brazil B1465/P2460 The Mechanism of Action of Molecular Iodine on MCF10A Cells from Fibrocystic Breast Tissue. Z.Z. Xu1, X. Chen1, N. Yam1, K. Chan1, U. Nagavarapu1; 1RD, BioPharm X, Menlo Park, CA

Muscle Structure, Function, and Disease B1466/P2461 Neuropeptide Y induces hematopoietic stem/progenitor cell mobilization by regulating matrix metalloproteinase-9 activity through Y1 receptor in osteoblasts. H. Jin1, M. Park2, N. Kim2, J. Lee2, J. Bae2; 1College of Veterinary Medicine, Kyungpook National University, Daegu, Korea, 2School of Medicine, Kyungpook National University, Daegu, Korea B1467/P2462 Inhibition of fibroblast activation to the myofibroblast phenotype in neonatal rat cardiac fibroblasts using a small molecule aldehyde trap. S.G. Macdonald1, F. Sachse2, C. Hunter2, H. Duffy3, V. Cullen1, S.L. Young1; 1Research and Development, Aldeyra Therapeutics, Lexington, MA, 2 Cardiovascular Research Division, University of Utah, Salt Lake City, UT, 3 Principal, Creative Innovation Consulting, Auburndale, MA B1468/P2463 Construction of the multidrug-sensitive yeast strain for elucidating the mechanism of the readthrough activity of (+)-negamycin and its analogues. K. Hamada1, A. Taguchi1, M. Kobayashi1, K. Takayama1, T. Usui2, Y. Hayashi1; 1Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan, 2Faculty of Life and Environmental Science, University of Tsukuba, Tsukuba, Japan

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B1451/P2446 Protective effects of medicinal bean extracts against nonalcoholic fatty liver disease. Y. Kim1, A. Im1, K. Song2; 1KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea, 2 Mibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea

Tuesday Poster Session

Board No./Presentation No. B1469/P2464 Rapid phenotypic assessment for mutations involved in human diseases: Uncovering a novel model for cardiac arrhythmia in the nematode C. elegans. Y.M. Clovis1, A. Webb1, C. Turner1, K.E. McCormick1, S.R. Lockery1; 1RD, NemaMetrix Inc., Eugene, OR B1470/P2465 Coordination of nuclear movement by bocksbeutel (Drosophila emerin). T.R. Mandigo1, M.R. Hussey1, E.S. Folker1; 1Biology, Boston College, Chestnut Hill, MA B1471/P2466 Structural basis for the effective myostatin inhibitory activity of the minimum peptide originated from mouse myostatin prodomain. K. Takayama1, T. Asari1, A. Nakamura1, Y. Saga1, T. Shimada1, A. Taguchi1, Y. Hayashi1; 1Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan B1472/P2467 Ex1, a potential exercise mimetic, rejuvenated skeletal muscle via PGC-1α induction. J. Bae1,2, H. Jeong1,2, A. Jo1,2, J. Shin1,2, J. Kang1,2; 1Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea, South, 2Samsung Biomedical Research Institute, Suwon, Korea, South B1473/P2468 Coenzyme Q10 as a antioxidant supplement therapy for dystrophic muscle cells. D.S. Mizobuti1, C.C. de Lourenço1, A. Macedo1, T.A. Hermes1, E. Minatel1; 1BIOLOGIA ESTRUTURAL E FUNCIONAL, UNICAMP, CAMPINAS, Brazil B1474/P2469 Investigation of a new hypoxia model to induce cardiomyocyte proliferation in zebrafish. F. Frech1, J. Sanchez2, B. Schoffstall1; 1Department of Biology, Barry University, Miami Shores, FL, 2 Physician Assistant Program, Methodist University, Fayetteville, NC B1475/P2470 Diacerhein effects on inflammatory and oxidative stress pathways in the diaphragm muscle of mdx mice. R.D. Mâncio1, T.A. Hermes1, I.F. Rupcic1, E. Minatel1; 1BIOLOGIA ESTRUTURAL E FUNCIONAL, UNICAMP, CAMPINAS, Brazil B1476/P2471 The contribution of flightin to cellular and thick filament biomechanics. J.O. Vigoreaux1, B.C. Tanner2, N. Gasek1, S. Chakravorty3; 1Biology, University of Vermont, Burlington, VT, 2Integrative Physiology and Neuroscience, Washington State University, Pullman, WA, 3Metabolic Disease Research Program, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

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Tuesday Poster Session B1477/P2472 Targeting mechanisms that regulate Sarcomere formation, homeostasis and function using a Nemaline Myopathy model. M. Balakrishnan1, S. Yu2, S.M. Chin3, B. Goode3, M.K. Baylies4; 1Developmental Biology, Weill Graduate School of Biomedical Sciences, Cornell Medical School, New York, NY, 2Developmental Biology, Gerstner Graduate School, Memorial Sloan Kettering Cancer Center, New York, NY, 3Department of Biology, Brandeis University, Waltham, MA, 4 Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY B1478/P2473 Identification of novel HSPB1 binding proteins in skeletal muscle. Y. Kato1, Y. Kokaji1, A. Kushiya1, K. Yoshino2, A. Takeuchi3, M. Yamanoue1, Y. Shirai1, S. Ueda1; 1Agrobioscience, Kobe University, Kobe, Japan, 2Biosignal Research Center, Kobe University, Kobe, Japan, 3Analytical Laboratory, Kobe Pharmaceutical University, Kobe, Japan B1479/P2474 Limb-Girdle Muscular Dystrophy 2L Is Associated With a Defect in Phospholipid Scrambling Mediated by ANO5. J.M. Whitlock1, K. Yu1, Y. Cui1, H.C. Hartzell1; 1Cell Biology, Emory University, Atlanta, GA B1480/P2475 The E2F Pathway Regulates Metabolism in the Post-Natal Heart and Defines a Novel Biomarker of Dilated Cardiomyopathy: BDH1. J.L. Major1, A. Dewan1, M. Salih1, B. Tuana1,2; 1Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, 2Heart Institute, University of Ottawa Heart Institute, Ottawa, ON B1481/P2476 Retinoic acid signaling promotes cardiomyocyte survival in cardiac development and repair. F. Da Silva1, A. Schedl1, J. Ryler1; 1Institut de Biologie Valrose, University of Nice Sophia Antipolis, Nice, France B1482/P2477 Ethanol treatment reduces myoblast fusion in culture. O.M. Kielbasa1, C. Brough1; 1Biology Program, Department of Science and Mathematics, Alvernia University, Reading, PA

B1484/P2479 mTOR-dependent regulation of CyclinD3 expression by R-spondin controls a transition from proliferation to myogenic differentiation of skeletal muscle stem cells. X. Han1, T.T. Tran2, J. Sah2, J. Yoon2; 1Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME, 2 Soonchunhynag Institute of Medi-Bio Science, Cheonan, Korea, South B1485/P2480 Astragalin Inhibits cigarette smoking-driven Infiltration of inflammatory cells in OVAchallenged Mice. Y. Kim1, Y. Choi2, Y. Kang1; 1Department of Food Science and Nutrition, Hallym University, Chuncheon, Kangwon-do, Korea, South, 2Nutritioal Product RD Team, Maeil Innovation Center, Gyeonggi-do, Korea, South B1486/P2481 Evolutionary adaptations in developmental pathways underlie regenerative scar-free wound repair in African Spiny Mice. C.M. Brewer1,2, B. Nelson3, X. Dong1, P. Wakenight3, A. Mckenna4, J. Shendure4, K. Millen3,5, M.W. Majesky1,2,5; 1Center for Developmental Biology and Regenerative Medicine, Seattle Children’s Research Institute, Seattle, WA, 2Pathology, University of Washington, Seattle, WA, 3Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, WA, 4Genome Sciences, University of Washington, Seattle, WA, 5 Pediatrics, University of Washington, Seattle, WA B1487/P2482 Cardiac β-AR, oxidative stress and MT1 are modified by GCSF in mice with heart damage induced by repeated β-adrenergic stimulation with isoproterenol. B. Nieto-Lima1,2, L. Pineda-Benítez2, G. Zarco-Olvera3, C. Huesca-Gómez2, V. Guarner-Lans2, A. Cano-Martínez2; 1Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de Mexico, Mexico city, Mexico, 2Department of Physiology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico city, Mexico, 3Department of pharmacology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico city, Mexico

B1483/P2478 A new model for how the actomyosin complex within myofibrils disassemble during muscle wasting upon fasting, aging and human disease suggests a two-phase highly regulated process. A. Volodin1, I. Kosti1, A.L. Goldberg2, S. Cohen1; 1Biology, Technion Institute of Technology, Haifa, Israel, 2Cell biology, Harvard Medical School, Boston, MA

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX

AUTHOR INDEX

Oral Presentations These numbers refer to the presentation numbers (not the board numbers) for each poster. Oral Presentation Authors are listed in the Program.

A

A, Mu ...................................................................P81 Aaron, Holly .........................................................P37 Abad, Janna ........................................................P38 Abad, Patricia C. ...............................................P334 Abad Fernandez, Maria Alba ...........................P1066 Abarzua, Sebastian .........................................P1366 Abbas, Amal ......................................................P600 Abdedin Sigg, Monika .......................................P152 Abdel Qader, Wadey K. ........................... P532,P534 Abdenur, Jose .................................................P1336 Abdukassimova, Meruyert ...............................P1087 Abdullah, Amira ...............................................P1062 Abdullah, Hiba .................................................P2209 Abdullah, Nazish .............................................P2213 Abdul-Sater, Zahi ...............................................P217 Abdurehman, Leymaan ...................................P1209 Abe, Hiroshi .........................................................P77 Abe, Jun-ichi ..........������������������������������� P869,P2198 Abe, Kouki ........................................����������������P928 Abe, Shigeru ..........�����������������������������������������P1625 Abel, Steven ..........�����������������������������������������P1849 Abell, Amy N. ..........����������������������������������������P2277 Abendroth, Austin ..........��������������������������������� P1191 Abiko, Hiyori ..........�������������������������������������������P610 Abood, Steven ..........��������������������������������������P1053 Aboona, Alan ..........����������������������������������������P1013 Abousawan, John ..........����������������������� P395,P2210 Abraham, Libin ..........���������������������������������������P933 Abraham, Madelyn J. ..........��������������� P1515,P1517 Abramowitz, Lara K. .........................��������������P1369 Abrash, Elizabeth ..........���������������������������������P1202 Abuna, Rodrigo P. ..........�����������������������������������P818 Acerbi, Irene ..........����������������������������������������� P1158 Acevedo, Maria ..........������������������������������������P2049 Acevedo-Díaz, Ariana ..........�����������������������������P276 Acharya, Dhiraj ..........������������������������ P2382, P2384 Acheva, Anna R. ..........�����������������������������������P1980 Ackerman, Sarah D. ..........���� P1317, P1583, P2379 Acosta-Alvear, Diego ..........����������������P1509, P1511 Ad, Omer ..........������������������������������������������������P806 Adam, Cecile ..........������������������������������������������P791 Adam, Pascal ..........����������������������������P1119,P2212 Adamian, Yvess ..........�������������������������� P283,P1947 Adams, Bruce ..........������������������������������� P333,P867 Adams, David R. ..........����������������������������������P1281 Adams, Gregory ..........�����������������������������������P2143 Adams, Mark N. ..........������������������������������������P1442 AdamsJr, Gregory ..........��������������������������������P2145 Adar, Shai ..........�������������������������������� P1834, P1868 Adelstein, Robert S. .......... P945,P949,P952, P1193, ������������������������������������������������������������ P1578,P1712 Adhikari, Arjun S. ..........������������������������ P943,P2225 Adikaram, Poorni R. ..........�������������������������������P301 Adikes, Rebecca C. ..........������������������������������P1800 Adjibade, Pauline ..........��������������������������������� P1194 Adrian, Thomas E. ������������������������������������������P1927 Affar, El Bachir ����������������������������������������������������P52 Affolter, Markus �����������������������������������������������P2364 Afonso, Olga ���������������������������������������������������P2143 Afroz, Sonia ����������������������������������������������������P1504 Afzal, Junaid ��������������������������������������������������� P1170 Agajanian, Megan ������������������������������������������P1947 Agard, David A. �������������������P808, P971,P972,P990 Agarwal, Meetu ����������������������������������������������P1594 Agarwal, Shivangi �������������������������������������������P1898 Ageta-Ishihara, Natsumi ���������������������������������P2122 Agrawal, Ashutosh ������������������������������������������P1220 Agre, Melody ��������������������������������������������������P1641 Agredano, Lourdes T. �������������������������������������P1234 Agresti, Jeremy ������������������������������������������������P890 Agus, David ������������������������������������������������������P285

Aher, Amol B. ����������������������������������������������������P139 Ahlers, Carolyn G. ��������������������������������������������P464 Ahlskog, Nina ������������������������������������� P1515,P1517 Ahmad, Ejaz ���������������������������������������������������P1026 Ahmed, Mehboob �������������������������������������������P1538 Ahmed, Shawn �������������������������������������������������P746 Ahmed, Yashi ���������������������������������������������������P559 Ahn, Erin ����������������������������������������������� P657,P1404 Ahn, Ji-Seon ��������������������������������������� P1381,P1382 Ahn, Ju-Hyun ������������������������������������������ P225,P250 Ahn, Natalie ����������������������������������������������������P1430 Ahn, Woosung ��������������������P461,P821,P823,P2380 Ahn, Yu-Hyeon �����������������������������������������������P1581 Ahnn, Joohong �������������������������������������������������P742 Ahrens, Daniel G. ���������������������������������������������P595 Ahrens, Paige �������������������������������������������������P2377 Aiken, Achilles ������������������������������������������������P1270 Aiken, Jayne E. ���������������������������������� P1796,P1797 Ainscough, Justin F. ���������������������������������������P2043 Aissaoui, Nesrine �������������������������������������������P1456 AitBlal, Carl Hammou ����������������������������������������������� ..................................P507,P508,P623,P1675,P1782 Akabane, Shiori ������������������������������������������������P525 Akamatsu, Matthew S. ���������������������������P392, P411 Akan, Ilhan �����������������������������������������������������P2010 Akatsu, Hiroyasu ��������������������������������������������P1383 Akera, Takashi ��������������������������������������������������P249 Åkesson, Lovisa ������ P507,P508,P623,P859,P1227, �������������������������������������������������������������P1128,P1782 Akhmanova, Anna ���������������������P139,P1078,P2358 Akhtar, Tasleem ����������������������������������������������P2442 Akiyama, Tetsu �������������������������������������������������P352 Aknoun, Sherazade ��������������������������������������������P45 Akram, Saad U. ����������������������������������������������P2297 Aksenova, Vasilisa ������������������������������������������P1210 Aksenova, Veronika ������������������������������������������P451 Aksu, Metin �����������������������������������������������������P2031 Aktas, Ranan G. ����������������������������������� P526,P1921 Alaimo, Laura ���������������������������������������������������P734 Alam, Catharina M. �����������������������������������������P1330 Alam, Md Badrul �������������������������������� P1644, P1646 Alamos, Juan S. ��������������������������������������������� P1189 Alanko, Jonna H. ����������������������������������������������P402 Alarcon, Sebastian �����������������������������������������P2185 Albadrani, Ghadeer ����������������������������������������P2043 Albaghjati, Abe �����������������������������������������������P1866 Albarran, Camila ������������������������������������ P514, P672 Al-Bassam, Jawdat M. ����������������������� P1789, P1795 Albeck, John �����������������������������������������������������P560 Alber, Mark S. �������������������������������������������������P1812 Alberico, Emily O. �������������������������������������������P1704 Albert, Istvan ��������������������������������������������������P2393 Albert, Marvin �������������������������������������������������P2264 Albert, Sahradha ��������������������������������������������P2091 Alberti, Simon ������������������������������ P626,P700,P1184 Albiges-Rizo, Corinne �������������������������������������P2289 Albrecht, Lauren V. �����������������������������������������P1385 Alderman, Christopher �����������������������������������P1942 Alevizos, Ilias ����������������������������������������������������P576 Alexander, Chris �����������������������������������������������P959 Alexander, Christopher J. ���������������������������������P481 Alexander, Guillermo M. ���������������������������������P1320 Alexander, Matthew R. �����������������������������������P2238 Alexander, Richard �����������������������������������������P2389 Alfandari, Dominique ��������������������������������������P1560 Alford, Lea M. ����������������P841,P1001, P1002,P1012 AlHashimi, Hikmat ��������������������������������������������P627 Al-hejjaj, Murtakab ��������������������������������������������P870 AlHrout, Ala’a ��������������������������������������������������P1927 Ali, Mourad �����������������������������������������������������P1925 Aligbe, Onyedikachi ���������������������������������������� P1411 Alizadeh, Elaheh ��������������������������� P305,P306,P723 Al-Juboori, Saif I. ����������������������������������������������P530

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Alkuraya, Fowzan S. ������������������������������������������P98 Allan, Douglas W. ������������������������������������������� P2113 Allard, Bailey A. ����������������������������������������������P1832 Allard, Corey ������������������������������������������� P594,P732 Allen, Benjamin L. ��������������������������������������������P569 Allgood, Samual C. �����������������������������������������P2425 Allio, Guillaume ���������������������������������������������� P1138 Allison, Rachel ������������������������������������������������P2095 Allshire, Robin ������������������������������������������������P1995 Alm, Tove L. ������������������������P58,P507,P1675,P1683 Almeida, Adriana L. �������������������������������� P814,P817 Almeida, Neil ����������������������������������������������������P792 Almeida, Raphael G. ��������������������������������������P1317 Alms, Cindy ������������������������������������������������������P190 Aloisio, Francesca M. �������������������������������������P1736 Alomer, Reem ���������������������������������������������������P236 Alonso, Annabel ���������������������������������������������P1788 Alpini, Gianfranco ���������������������������������������������P344 Altan-Bonnet, Nihal ����������������������������������������P1071 Altschuler, Steven J. �����������������������������������������P617 Alushin, Gregory M. ����������������������� P909,P917,P957 Alvarado, José ��������������������������������������������������P915 Alvarez, Alvaro �����������������������������������������������P1422 Alvarez De Prax, Marisa C. ������������������������������P265 Alvarez-Hernandez, Georgina ������������������������P1234 Alveraz, Steven ������������������������������������������������P598 Alves, Cleidson �������������������������������������������������P339 Alves, Daiane S. �����������������������������������������������P264 Alvey, Cory M. ������������������������������������������������ P1141 Alwood, Joshua S. ������������������������������������������P1953 Amack, Jeffrey ������������������������������������������������P1548 Amalric, Nicolas ����������������������������������������������P2443 Aman, Jurjan ����������������������������������������������������P668 Amano, Mutsuki ����������������������������������������������P2195 Amaro Gonzalez, Elizabeth ����������������������������P1693 Amato, Clelia ����������������������������������������������������P105 Amberg-Johnson, Katherine ���������������������������P1595 Ambrosini, Arnaud ������������������������������������������P1455 Ambrosio, Andrea L. ���������������������������������������P1273 Amezcua, Karina ��������������������������������������������P2144 Amezcua, Natalee ������������������������������������������P2144 Amigo, Morgan �������������������������������������������������P757 Amin, Amr �������������������������������������������������������P1927 Amin, Mohammed ������������������������������������������P1900 Amir, Ariel ���������������������������������������������������������P795 Amos, Brianna ��������������������������������������������������P349 Ampe, Christophe �������������������������������������������P1719 Ampuero, Estibaliz �����������������������������������������P1366 An, Hong-Yan �������������������������������������������������P1646 Anand, Aditya �������������������������������������������������P1206 Ananthanarayanan, Badriprasad ����������������������P314 Anantharam, Arun ������������������������������������������P2064 Anders, Robert A. �������������������������������������������P1707 Andersen, Erich E. �����������������������������������������P1633 Andersen, Ina T. ���������������������������������������������P1665 Andersen, Jens S. ��������������������������������������������P146 Anderson, Caitlin A. ������������������������������������������P891 Anderson, Daniel J. ����������������������������������������P1916 Anderson, Dorian ���������������������������������������������P770 Anderson, James W. ��������������������������������������P1024 Anderson, James M. ��������������������������������������P1458 Anderson, Karen E. ����������������������������������������P1431 Anderson, Matthew T. ���������������������������������������P926 Anderson, Nadine S. ��������������������������������������P2060 Anderson, Tyler C. ������������������������������������������ P1100 Anderson, Wesley ������������������������������������������P2377 André, Diana M. ���������������������������������������������P1500 Andres Terre, Marta ����������������������������������������P1629 Andrianifahanana, Mahefatiana �����������������������P467 Andrieux, Annie ����������������������������������������������P1794 Angarola, Brittany L. ���������������������������������������P1283 Angeles-Albores, David ������������������������������������P888 AngelesJuanes-Ortiz, Maria �������������������������������P90

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AUTHOR INDEX Anilkumar, Ambika A. ����������������������������������������P937 Anilkumar, Anupama A. ������������������������ P930,P1356 Annabi, Christopher ����������������������������������������P1607 Annabi, Joey ���������������������������������������������������P1607 Anneken, Alexander �����������������������������������������P453 Anselme, Karine ��������������������������������� P2216,P2287 Antfolk, Daniel ��������������������������������������������������P628 Antila, Christian ������������������������������������������������P628 Antoku, Susumu ������������������������������������� P374,P462 Antonescu, Costin N. ����������������� P395,P396, P1085, ������������������������������������������������� P1121,P1245,P2210 Antonin, Wolfram �������������������������������� P1216,P1801 Antoshechkin, Igor ��������������������������������������������P888 Antunes, Edson ����������������������������������������������P1500 Anzola, John V. �����������������������������������������������P1038 Ao, Mingfang �������������������������������������������������� P1155 Aoh, Quyen L. ������������������������������������������������P1272 Aoki, Kana ��������������������������������������������������������P927 Aonbangkhen, Chanat ������������������������������������P1058 Aoyama, Fumiyo ��������������������������������������������P1249 Aparicio, Renan E. �������������������������������������������P428 Apodaca, Gerard ����������������������������������������������P442 Appathurai, Suhila ������������������������������������������P1508 Apte, Suneel S. ����������������������������������������������P1317 Arachchige Don, Aruni �������������������������� P293,P2125 Aradi, Al E. ������������������������������������������������������P1273 Arai, Naoki ������������������������������������������������������P2009 Araki, Yasuhiro �����������������������������������������������P1392 Aranjuez, George �������������������������������������������P1433 Arasaki, Kohei ������������������������������������ P1350,P2052 Arbach, Hannah E. �����������������������������������������P2028 Ard, Ryan �������������������������������������������������������P1995 Areias, Anabela C. ��������������������������������������������P727 Arellano-Garcia, Caroline �������������������������������P1482 Ariatti, Allison ��������������������������������������������������P2086 Ariga, Kosuke �������������������������������������������������P1758 Aritomo, Ryota ������������������������������������������������P1459 Arjonen, Antti ����������������������������������������������������P402 Arju, Rezina ���������������������������������������� P1974,P1975 Arkin, Michelle R. �������������������������������������������P1999 Arnandis, Teresa ���������������������������������������������P1079 Arnaoutov, Alexei ��������������������������������������������P1210 Arnold, Christopher P. �������������������������������������P2420 Arnold, Craig B. ������������������������������������������������P714 Arnold, Torey R. ����������������P465, P635, P640,P2367 Arnspang, Eva C. ������������������������������� P1359,P1665 Arora, Gaurav ���������������������������������������������������P831 Arora, Pamela D. ����������������������������������������������P652 Arora, Sonali �����������������������������������������������������P788 Arpag, Goker ����������������������������������������������������P127 ArriagadaMomberg, Cecilia L. ��������������������������P425 Arrial, Alexis ������������������������������������������������������P866 Arron, Sarah T. ����������������������������������������������� P1134 Artiga, Marcela S. �����������������������������������������������P68 Arulanandam, Jeyaprakash ���������������� P1066,P1067 Arumugaswami, Vaithilingaraja ����������������������P1606 Arvedon, Jaclyn ����������������������������������������������P1562 Arya, Subhash B. �������������������������������P1123, P2076 Asada, Akiko �����������������������������������������������������P434 Asada, Rie ������������������������������������������������������P1041 Asai, Naoya ������������������������������������������������������P787 Asamoto, Ciara ����������������������������������������������� P1191 Asanuma, Ken ������������������������������������������������P2181 Asari, Tomo �����������������������������������������������������P2466 Asbrock, Nick J. ����������������������������������������������P1956 Asbury, Charles L. ��������������������� P130,P1897,P1912 Asensio, Cedric S. ������������������������������������������P1294 Ashihara, Eishi �������������������������������������������������P261 Ashkenazi, Avi ��������������������������������������������������P675 Ashley, Euan �������������������������������������������������������P67 Asirvatham, Angela L. ���������������������������� P589,P590 Aslan, Joseph �������������������������������������������������P1365 Asnacios, Atef �������������������������������������������������P2219 Asselin, Eric �����������������������������������������P1119,P2212 Asthagiri, Anand R. �����������������������������������������P2175 Asthana, Saurabh �������������������������������������������P2319 Astor, Michael T. ������������������������������������� P702,P703 Atieh, Youmna ������������������������������������������������ P1154 Atomi, Yoriko ��������������������������������������������������P2301 AtrianAfyani, Farzaneh �����������������������������������P1235 Attardi, Laura ��������������������������������������������������P1077 Attia, Rafaele ����������������������������������������������������P376 Au, FrancoKinChung ��������������������������������������P1078 Aubry, Laurence ���������������������������������������������P1794

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Audhya, Anjon ��������������������������������������������������P193 Auer, Manfred �������������������������������������������������P1475 Augustine, Beryl �����������������������������������������������P251 Auld, Alexander L. ������������������������������������������P1718 Auld, Vanessa J. ���������������������������� P302,P638,P765 Aumeier, Charlotte ��������������������������������������������P129 Austin, Timothy O. ������������������������������������������P1784 Austriaco, Nicanor ���������������������������������� P690,P709 Avasthi, Prachee �� P161,P162,P1817,P1822,P1835 Avery, Adam W. ������������������������������������������������P473 Aviad, Tamar �����������������������������������������������������P415 Avinoam, Ori ���������������������������������������������������P2088 Avsaroglu, Baris ���������������������������������������������P1873 Awadia, Sahezeel ��������������������������������� P465,P2174 Awadová, Thuraya ��������������������������������������������P357 Awasthi, Mayanka ������������������������������������������P1831 Awuah, Afua ���������������������������������������������������P2449 Aydin, Mehmet S. ���������������������������������������������P526 Ayee, Brian G. ������������������������������������������������P1727 Azaizeh, Wesam ���������������������������������������������P1054 Azevedo, Joana M. �������������������������������������������P668 Azevedo, Mafalda ���������������������������������������������P772 Aznar, Nicolas ��������������������������������������������������P307 Azpurua, JorgeE ���������������������������������������������P1664 Azuara, Paulina M. ����������������������������� P1231,P2023 Azurin, Emma T. ���������������������������������������������P2062

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Baarlink, Christian ��������������������������������� P106, P319 Baars, Matthijs ������������������������������������������������P2358 Baas, Peter W. ������������������������� P974,P1784, P1320 Baba, Kentarou ������������������������������������������������P928 Baba, Satoshi ���������������������������������������������������P429 Babataheri, Avin ���������������������������������������������P2220 Bachant, Jeff �����������������������������������������������������P196 Backer, Jonathan M. ���������������������������������������P2240 Bäckström, Anna ����������������P507,P508,P623,P1675 Badache, Ali �������������������������������������������������������P90 Badache, Hakima �������������������������������������������P1480 Badea, Alexandra �������������������������������������������P1302 Bader, Almke ����������������������������������������������������P629 Bader, David �����������������������������������������������������P954 Badgandi, Hemant B. �������������������������������������P1828 Badger, Benjamin L. ���������������������������������������P1899 Badillo-Rivera, Keyla ����������������������������������������P987 Badu-Nkansah, Kwabena A. ����������������������������P644 Bae, Cheol-Hyeon ������������������������������������������P1581 Bae, In-Seon ��������������������������������������������������P1204 Bae, Jae-sung ������������������������������������������������P2461 Bae, Ju-Hyeon ������������������������������������������������P2467 Bae, SunSik ������������������������������������������������������P556 Baehler, Martin �������������������������������������������������P947 Baek, Seung-hwa �������������������������������������������P1646 Baeza, Victor M. ���������������������������������������������P1007 Baez-Vega, Perla �������������������������������������������P1969 Bahl, Disha �����������������������������������������������������P2333 Bai, Haiqing ����������������������������������������������������P2103 Bai, Jian ����������������������������������������������������������P1862 Bai, Jihong ������������������������������������������������������P1316 Bai, Xiaofei ��������������������������������������������� P179,P182 Baig, Badriya ��������������������������������������������������P1927 Bailey, Eric ������������������������������������������������������P1608 Bailey, Megan ���������������������������������������������������P130 Bainer, Russell �����������������������������������������������P1997 Baird, Barbara A. ��������������������������������������������P1409 Baird, Michelle A. ���������������P593, P917,P952,P1471 Bajpai, Prachi ������������������������������������������������� P1132 Bakal, Chris ������������������������������������������������������P605 Bakalar, Matthew H. �����������������������������������������P588 Baker, Aaron B. ����������������������������������������������P2285 Baker, David �����������������������������������������������������P646 Baker, Erin J. ������������������������������������������������������P64 Baker, James ��������������������������������������������������P1562 Baker, Julie C. ��������������������������������������������������P987 Baker, Ruth �������������������������������������������������������P760 Baker, Susan C. ���������������������������������������������P1601 Bakst, Richard ��������������������������������������������������P324 Balabiyev, Arnat ������������������������������������ P134,P1087 Balachandran, Riju S. �������������������������������������P1024 Balakrishnan, Mridula �������������������������������������P2472

Balakrishnan, Sanjeev ������������������������������������P1957 Balasinor, Nafisa H. ��������������������������������������������P76 Balasubramanian, Mohan ������������������ P1745,P1853 Balážová, Mária ������������������������������������������������P357 Balchand, SaiKeshavan ���������������������������������P1891 Baldassano, Robert ������������������������������������������P827 Baldwin, Enoch P. ���������������������������������������������P803 Balistreri, Giuseppe ������������������������������������������P925 Balkwill, Frances ����������������������������������������������P229 Ball, David A. ��������������������������������������������������P1668 Balla, Tamas ��������������������������������������� P1362,P1416 Ballesteros, Ivan �����������������������������������������������P789 Baluch, Debra P. ���������������������������������������������P1641 Bamshad, Michael J. ����������������������������������������P945 Band, Hamid ���������������������������������������������������P1263 Bandaria, Jigar �����������������������������������������������P1992 Banerjee, Animesh �����������������������������������������P2383 Banerjee, Shamik �������������������������������������������P2085 Banerjee, Shiladitya �����������������������������������������P919 Banfield, David K. ���������������������������������������������P421 Bangasser, Patrick F. ��������������������������������������P2233 Bankaitis, Vytas A. ������������������������������������������P2374 Banker, Gary ���������������������������������������������������� P117 Banks, Lawrence...P302,P465,P1126,P1244,P1604, .........................................................................P1605 Banks, Peter ������������������������������������������� P57,P1088 Bankston, Andrew N. ��������������������������������������P2318 Bansal, Ruchi ���������������������������������������������������P159 Banskota, Suhrid ���������������������������������� P567,P1930 Banu, Khadija ������������������������������������������������� P1197 Bao, Menjing ����������������������������������������������������P427 Bao, Zhirong �������������������������������������������������������P44 Barajas, Ana �����������������������������������������������������P534 Barakat, Abdul I. ���������������������������������������������P2220 Barakat, Khaled H. �����������������������������������������P1537 Baral, Sonu S. ������������������������������������ P1222,P1223 Baranzini, Sergio E. ����������������������������������������P1639 Baratova, Ludmila A. ��������������������������������������P1488 Barattin-Voynova, Natalia S. �������������������������� P1192 Barber, Diane L. ��������������������������������� P1736,P2281 Barbera, Dylan �������������������������������������������������P976 Barbieri, Manuel A. �����������P552,P786,P1053,P1627 Barbosa-Lorenzi, Valeria C. ������������������������������P579 Barbosa-Sampaio, Helena C. ���������������������������P562 Barbot, Mariam �������������������������������������������������P521 Bard, Frederic A. ����������������������������������������������P322 Bardag-Gorce, Fawzia �����������������������������������P2314 Bardin, Sabine ������������������������������������ P1287,P1288 Barford, Kelly ��������������������������������������������������P1301 Barger, Sarah R. ���������������������������������������������P1742 Barinaga-RementeriaRamirez, Irene ��������������P1265 Baris, Adrian ���������������������������������������������������P2140 Barisíc, Marin ���������������������������������������������������P218 Barkla, Bronwyn J. �������������������������������������������P775 Barlowe, Charles ��������������������������������������������P2060 Barnes, Georjana �������������������������������������������P1806 Barnes, James M. ������������������������������������������ P1160 Barnes, Ryan ��������������������������������������������������P1097 Barnhardt, Cole A. ������������������������������ P1552,P2350 Baron, Sylvain ������������������������������������������������P2458 Baron, William ������������������������������������������������P2203 Barr, Dana B. ��������������������������������������������������P1289 Barr, Kevin J. ��������������������������������������������������P2272 Barr, Maureen M. ����������������������������������������������P992 Barragan, Iris ��������������������������������������������������P2099 Barral, Duarte C. ��������������������������������������������P1274 Barral, Yves ������������������������������������������������������P539 Barratt, Stephen �����������������������������������������������P105 Barravecchia, Michael ������������������������������������P2103 Barrera, Francisco N. ���������������������������������������P264 Barrero, Juan J. ������������������������������������������������P422 Barres, Ben ����������������������������������������������������P2379 Barrett, Kim ����������������������������������������������������P1616 Barron, Francie E. ������������������������������������������P2334 Barros, Felipe ���������������������������������������������������P529 Barroso, Margarida M. ������������������������ P1269,P1331 Barrott, Jared J. ������������������������������������������������P296 Barry, Rachel ����������������������������������������������������P803 Barske, Lindsey ������������������������������������������������P790 Barsukov, Igor �������������������������������������������������P1439 Barth, Angela ��������������������������������������������������P1423 Bartholomai, Bradley M. �����������������������������������P362

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Bartolini, Francesca �������������������������������� P492,P493 Barton, Lance F. ������������������������ P843,P1118,P1915 Bartova, Eva ���������������������������������������������������P1225 Barwig, Mark ��������������������������������������������������P2279 Bas, Guniz ��������������������������������������������������������P373 Basbaum, Allan ����������������������������������������������P1667 Baskaran, Sulochanadevi �������������������������������P2316 Baskevitch, Kayla S. ���������������������������������������P1873 Basom, Ryan S. �����������������������������������������������P788 Bassereau, Patricia ����������������������������������������P1447 Bassik, Michael C. ������������������������������������������P2419 Bastidas, Robert ���������������������������������������������P2410 Basto, Renata �������������������������������� P155,P180,P228 Bastounis, Effie E. ������������������������������ P2214,P2407 Basu, Sukanya �����������������������������������������������P2179 Bateman, Jack ��������������������������������������������������P201 Bates, Emily ���������������������������������������������������P1797 Bates, Mark ��������������������������������������� P1657, P1666 Bateup, Helen �������������������������������������������������P2394 Batista, CesarF. ����������������������������������������������P1678 Battersby, Brendan J. �������������������������������������P1333 Baube, Charlie ��������������������������������������������������P841 Baudoin, Nicolaas C. ����������������������������������������P241 Bauer, Johann W. ������������������������������������������� P1168 Baugh, Keith W. ����������������������������������������������P2038 Baumeister, Wolfgang ������������������������� P939, P2091 Baumer, Claire M. ���������������������������������������������P986 Baumgart, Johannes ����������������������������������������P240 Bautista, Stephen ��������������������������������� P396,P1245 Bavouzet, Bruno ���������������������������������������������P2402 Bawazir, Nada ������������������������������������ P1441,P2087 Bayes, Joshua J. ��������������������������������������������P1873 Bayless, Kayla J. ����������������������������������������������P628 Baylies, Mary K. ����������������������������������� P772,P2472 Bazzaro, Martina ����������������������������������������������P142 Bazzoun, Dana B. ��������������������������������������������P631 Beach, Jordan ��������������������������������� P87,P955,P958 Beach, Jordan R. ��������������������������������������������P1712 Beaman, Henry ������������������������������������������������P551 Bean, Andrew J. ���������������������� P1252,P1257,P1258 Bear, James E. �������������������������������������������������P388 Bearce, Elizabeth A. �����������������������������������������P137 Bearer, Elaine L. ���������������������������������������������P1306 Beas, Anthony O. �������������������������������������������P1351 Beaufrère-Seron, Béatrice ������������������������������P1628 Beber, Alexandre ��������������������������������������������P1444 Becalska, Agata N. �������������������������������������������P397 Bechler, Marie E. ��������������������������������������������P2222 Bechtoldt, Natascha ���������������������������������������P1624 Beck, Martin ��������������������������������������� P1657,P2092 Becker, Annegret ����������������������������������������������P260 Becker, Ashley K. ���������������������������������������������P837 Becker, Jordan T. ��������������������������������������������P1634 Beckett, Alison ��������������������������������������������������P235 Beckham, Yvonne M. ������������������������������ P92,P2246 Bee, Yong M. ��������������������������������������������������P1637 Beer, Thomas �����������������������������������������������������P97 Beese, Allison M. ��������������������������������������������P1449 Begum, Salma ������������������������������������������������ P2116 Behling, Alex ���������������������������������������������������P1687 Behrends, Christian ����������������������������������������P1528 Beigbeder, Alice ������������������������������������������������P582 Beitman, Andrew J. ����������������������������������������P2238 Bekbayev, Sultan ����������������������������������������������P134 Bekier, Michael E. �������������������������������������������P1292 Belaidi, Jean-Philippe �������������������������������������P2302 Belanto, Joseph J. ������������������������������������������P1798 Belcher, Joyce Y. ��������������������������������������������P2449 Belenguer, Pascale ����������������������������������������P2451 Beliveau, Brian J. �������������������������������������������P1991 Belkina, Anna �������������������������������������������������P1566 Bell, Cheryl L. ���������������������������������������������������P634 Bell, Christina �������������������������������������������������P1251 Bell, Jessica K. �����������������������������������������������P2188 Bellec, Karen ��������������������������������������������������P2218 Bellin, Robert M. ���������������������������������������������P1693 Bellini, Maria H. ����������������������������������������������P1931 Belmonte, Julio M. ������������������������������������������P1653 Beloti, Marcio M. ��������� P659,P814,P817,P818,P889 Bembenek, Joshua N. ���������������������������� P179,P182 Bement, William M. ����������������������������� P2177,P2178

Benard, Emmanuelle ����������������������������������������P929 Benchimol, Thibaut �������������������������������������������P865 Bend, Eric G. ��������������������������������������������������P2136 Bender, Dawn E. ����������������������������������������������P239 Bendris, Nawal �������������������������������������������������P394 Benedetti, Kelli �������������������������������������������������P479 Benedetti, Lorena �����������������������������������������������P55 Benezra, Robert ���������������������������������������������P1968 Beningo, Karen A. ������������������������������������������P2235 Bennabi, Isma ������������������������������������������������P1031 Benner, Christopher ���������������������������������������P1038 Bennett, Alexis ������������������������������������������������P2137 Bennett, Margaret �������������������������������������������P1858 Bennett, Rachel R. �����������������������������������������P1228 Bennett, Vann ��������������������������������������� P388,P1302 Bennewith, Kevin L. ������������������������������������������P321 Benninghoff, Abby D. ����������������������������������������P345 Benson, Brandon ������������������������������������������������P19 Bentley, Marvin ������������������������������������������������� P117 Benzing, Thomas ��������������������������������������������P1005 Berasain, Carmen ��������������������������������������������P343 Berbari, Nicolas F. ���������������������������������� P159,P926 Bergant, Martina ���������������������������������������������P1605 Berger, Harald ������������������������������������������������P1995 Berger, Scott E. ������������������������������������������������P702 Bergeron, Richard ������������������������������ P1515,P1517 Bergman, Jared ������������������������������������������������P715 Bergman, Zane J. �������������������������������������������P1806 Bergmann, Jan H. ��������������������������������������������P343 Bergson, Clare �����������������������������������������������P1313 Bergstrom, Natalie ��������������������������������������������P681 Bermudez, Jessica G. ������������������� P737,P738,P739 Bernal, Miguel ��������������������������������������������������P812 Bernard, Christine ������������������������������������������P1678 Bernatchez, Pascal N. ������������������������������������P2244 Bernaudin, Clément ����������������������������������������P1463 Bernd, Karen K. ��������������������������������������������������P16 Bernens, Jordan N. ������������������������������������������P132 Bernlohr, David A. �������������������������������������������P1524 Berns, Michael ������������������������������������ P1324,P1855 Bernstein, Daniel ����������������������������������������������P943 Berrios, Daniel C. �������������������������������������������P1544 Berrios, Mike ��������������������������������������������������P1044 Berry, Jody ������������������������������������������������������P1618 Berry, Joel M. ��������������������������������������������������P1697 Bershadsky, Alexander D. ���������������������� P918,P953 Berteloite, Benjamin �����������������������������������������P875 Bertin, Aurelie ����������������P915,P1444,P1447, P1456 Bertinat, Romina ��������������������������������������������� P2114 Bertocchi, Cristina ������������������������������������������P1471 Berude, John C. ���������������������������������������������P1351 Beshay, Mariam ��������������������������������� P1441, P2087 BessaViana, Nathan ���������������������������������������P2287 Besson, Arnaud ����������������������������������������������P2239 Betleja, Ewelina ������������������������������������ P368,P1826 Betterton, Meredith �����������������������������������������P1020 Betzig, Eric �������P48,P87,P103,P179,P1429,P1441, ������������������������������������������������������������ P1712,P2139 Beussman, Douglas J. �����������������������������������P1013 Bewersdorf, Joerg ����������������������������������������������P55 Beyeler, Sarah A. �������������������������������������������� P2118 Bezanilla, Magdalena �������������������������������������P1705 Bhaban, Shreyas ����������������������������������������������P125 Bhabha, Gira ��������������������������������������� P802, P1766 Bhakta, Kishan �������������������������������������������������P283 Bhamla, Saad ��������������������������������������������� P17,P19 Bhandari, Rajan ����������������������������������������������P1568 Bhang, YongJoo ���������������������������������������������P1436 Bhargava, Aditi �����������������������������������������������P1420 Bhaskar, Rachel ���������������������������������������������P2436 Bhattacharya, Dipanjan ������������������������������������P721 Bhattarai, Kashi R. �����������������������������������������P1561 Bhattarai, Samip ��������������������������������������������� P2116 Bhattaram, Pallavi ��������������������������������������������P407 Bialecka-Fornal, Maja ������������������������� P1326,P2306 Bian, Xin �����������������������������������������������������������P537 Biancardi, Manoel F. ���������������������������������������P2459 Bianchini, Julie M. ������������������������������������������P1466 Bianchini, Paolo ������������������������������������������������P924 Bibeau, Jeffrey P. ����������������������������������������������P728 Biber, Sarah A. �����������������������������������������������P1253

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Bidaud-Meynard, Aurélien ����������������������������������P95 Bidone, Tamara C. ������������������������������������������P1846 Biebl, Julia ������������������������������������������������������P1438 Bièche, Ivan ���������������������������������������� P1250,P1979 Bielczyk-Maczynska, Ewa ������������������������������P1643 Bielecka, Zofia F. ��������������������������������������������P1954 Bieling, Peter ��������������������������������������������������P1398 Bielski, Craig M. �����������������������������������������������P288 Biesemann, Anja ��������������������������������������������P2070 Bigerelle, Maxence �����������������������������������������P2216 Bigerelle, Maxence �����������������������������������������P2287 Biggs, Ronald �������������������������������������������������P1546 Bigot, Anne �����������������������������������������������������P2236 Billington, Neil ����������������������������������������� P952,P965 Billmyre, Katherine �������������������������������������������P746 Binamé, Fabien ��������������������������������������������������P95 Binan, Loic ����������������������������������������������������������P52 Binder, April K. ��������������������������������������������������P681 Bindra, Ranjit S. ���������������������������������������������P2001 Binns, Derk �����������������������������������������������������P2142 BintiZain, Rosnah �������������������������������������������P1962 Bintu, Bogdan �������������������������������������������������P1991 Birnbaum, Ramon ������������������������������������������P1868 Bisaria, Anjali ��������������������������������������������������P1429 Bisher, Margaret E. �������������������������������������������P634 Bisht, Jitender S. ��������������������������������������������P1884 Bisht, Shveta ����������������������������������������������������P233 Bisnett, Brittany J. ��������������������������������������������P414 Bisson, Alexandre ���������������������������������������������P798 Bisson, Nicolas ��������������������������������������� P582,P584 Bitterman, Peter B. �������������������������������������������P820 Bittner, Carla X. ������������������������������������������������P529 Bivona, Trever ������������������������������������������������ P1122 Bizet, Albane ��������������������������������������������������P1839 Björk, Lars �������������� P507,P508,P623,P1675,P1782 Björkgren, Ida ���������������������������������������������������P756 Bjorkman, Pamela J. ����������������������������������������P498 Black, Ben E. �������������������������������������� P1062,P1063 Blackburn, Elizabeth H. ����������������������������������P1999 Blackburn, Jessica B. �������������������������� P420, P1289 Blackstone, Craig D. ��������������������������� P1268,P2139 Blackwell, Robert ��������������������������������������������P1020 Blacque, Oliver E. ������������������������������� P1840,P1841 Blaine, Judith ����������������������������������������������������P530 Blair, Jimmy A. ������������������������������������������������P2184 Blair, John �������������������������������������������������������P2394 Blais, Christian �����������������������������������������������P1318 Blaize, Jonathan �����������������������������������������������P259 Blakely, Randy D. �������������������������������������������P2130 Blanchoin, Laurent ������������������������������� P129,P1710 Blanco, Constanza �����������������������������������������P1437 Blanco, Gustavo ���������������������������������������������P1832 Blangy, Anne ���������������������������������������������������P2248 Blaschitz, Astrid ����������������������������������������������P2279 Blatche, Marie-Charline ������������������������������������P875 Blatchford, Katelyn �����������������������������������������P1419 Blazaskie, Michael ���������������������������������� P589,P590 Bloch, Robert J. ������������������������������������������������P624 Block, Jennifer ����������������������������������������������������P85 Blomen, Vincent �����������������������������������������������P200 Blondelle, Jordan ��������������������������������������������P1526 Bloom, Kerry ���������������������������������������������������P1899 Bloom, Trevor �������������������������������������������������������P9 Bloss, Tim �������������������������������������������������������P1516 Blouin, Cedric ��������������������������������������� P619,P2236 Blount, Jessica R. ���������������������������������������������P815 Blum, Yannick ���������������������������������������������������P717 Blume, Rostyslav Y. ���������������������������������������� P1177 Blume, Yaroslav B. �����������������������������������������P2322 Blumer, Kendall J. ������������������������������������������P1386 Blystone, Scott D. �����������������������������������������������P91 Boczek, Edgar ��������������������������������������������������P700 Bodakuntla, Satish �����������������������������������������P1785 Bodin, Stephane ���������������������������������������������P1250 Bodmer, Rolf �����������������������������������������������������P664 Bodmer, Zachary R. �����������������������������������������P305 Boese, Cody �����������������������������������������������������P206 Bogaczynska, Marta �����������������������������������������P756 Boggupalli, DeviPrasad ����������������������������������P1759 Bogorodskaya, Diana K. ���������������������������������P1793 Bogutz, Aaron B. ����������������������������������������������P649 Bohnert, Adam ��������������������������������������������������P745 Bohnert, K. A. ���������������������������������������������������P908 Böhning, Marc ������������������������������������������������P1666

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AUTHOR INDEX Bois, Justin S. ����������������������������������������� P452,P830 Boise, Lawrence H. �������������������������������� P661,P673 Bojja, SaiGowthami ����������������������������������������P1306 Bokinsky, Alexandra �������������������������������������������P44 Boldogh, Istvan R. ������������������������������������������P1749 Bolger, Timothy A. ������������������������������������������P1205 Bolger-Munro, Madison ������������������������������������P933 Bolgioni, Amanda F. ���������������������������������������� P1109 Bollozos, Athena ���������������������������������������������P1897 Boltz, Kara ������������������������������������������������������P1232 Bonaccorsi, Silvia ���������������������������������������������P204 Bonavita, Raffaella �����������������������������������������P1580 Bonazzi, Daria ��������������������������������������������������P445 Boncompain, Gaelle ��������������������������� P1287,P2092 Bond, Daniel R. ������������������������������������������������P806 Bond, Rachel K. ���������������������������������������������P1400 Bone, Leslie N. ��������������������������������������P396,P1121 Bonello, Teresa T. ���������������������������������������������P459 Bonini, Nancy M. ����������������������������������������������P348 Bonner, Alison N. ��������������������������������������������P1558 Bonomo, Raíza ���������������������������������������������������P74 Boo, Stellar �������������������������������������������������������P652 Boo, YongChool ����������������������������������������������P2286 Booissou, Anais ���������������������������������������������� P1711 Booker, Evan ��������������������������������������������������P1482 Boonen, Marielle ��������������������������������������������P1267 Booth, Daniel G. �����������������������������������������������P235 Booth, Elizabeth A. ���������������������������� P1618, P1844 Boothby, Thomas C. �����������������������������������������P696 Borah, Sapan ������������������������������������������������� P1211 Borden, Sean V. ���������������������������������������������P2001 Bordes, Nicole ������������������������������������������������P1073 Bordet, Thierry ������������������������������������������������P2451 Borenstein-Auerbach, Nofit ������������������������������P292 Borghi, Nicolas �����������������������������������������������P1463 Bork, Peer ������������������������������������������������������P2092 Boscher, Cecile ����������������������������������������������P2255 Boscheron, Cécile ������������������������������������������P1794 Bosompra, Oye ���������������������������������������������� P1190 Bosso, Giuseppe ����������������������������������������������P204 Bostick, Zoe ������������������������������������������������������ P117 Botelho, Roberto J. �������������������������������������������P396 Bothma, Jacques P. ������������������������������������������P793 Bott, Christopher J. �������������������������������������������P488 Botto, Jeanmarie ��������������������������������������������P2402 Boucekkine, Houda ����������������������������������������P1268 Boudaoud, Arezki ����������������������������������P445,P2115 Boudou, Thomas ��������������������������������������������P2289 Bouffard, Jeff ��������������������������������������������������P2175 Bouhlel, Imene B. �������������������������������������������P1073 Bouit, Lou �������������������������������������������������������P1856 Boulanger, Corinne A. ��������������������������������������P782 Boulanger, Jerome �����������������������������������������P1073 Boules, Mariam ����������������������������������������������P2437 Bourg, Julia ����������������������������������������������������P2064 Bousquet, Hugo ����������������������������������������������P1447 Bouten, Carlijn ��������������������������������������������������P628 Bouzelmat, Nassira ���������������������������������������� P1192 Bowen, Caitlin ��������������������������������������������������P945 Bower, Raquel ������������������������������������ P1012,P1814 Bowers, Jackson T. �������������������������������������������P141 Bowie, Laura E. ����������������������������������������������P2457 Bowman, John ������������������������������������������������P1201 Bowtell, David ���������������������������������������������������P229 Boyce, Andrew K. ���������������������������������������������P387 Boyce, Michael ������������������������������������� P414,P1370 Boyer, Nicholas ������������������������������������������������P892 Boyko, Valery ��������������������������������������������������P1544 Boyle, Judith A. �����������������������������������������������P1273 Braas, Daniel ��������������������������������������������������P2392 Brabander, Jef D. �������������������������������������������P1955 Bracho-Rincon, Dina P. ����������������������������������P1521 Bradford, Chastity N. ����������������������������������������P810 Bradley, Alexander O. �������������������������������������P1728 Bradley, Roger ������������������������������������������������P1460 Bradshaw, Niels ����������������������������������������������P1399 Braet, Filip ����������������������������������������������������������P31 Braga, Marina S. ��������������������������������������������P1931 Brakebusch, Cord H. ���������������������������������� P85,P93 Brambilla, Daniel C. ����������������������������������������P1947 Brand, Andrea H. ��������������������������������������������P2386 Brand, Christoph A. �������������������������������P611,P2231 Brandman, Onn ����������������������������������������������P1520

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Brandt, James ��������������������������������������������������P440 Brangwynne, Clifford P. ������������������������ P714,P1697 Brar, Gloria A. ��������������������������������������P1195,P1877 Braun, Alexander ������������������������������������ P145,P660 Braun, Jan ������������������������������������������������������P1522 Braun, Thomas �������������������������������������������������P257 Brauns, Ann-Kristin �������������������������������������������P522 Braverman, Nancy ������������������������������������������P2151 Bravo-Cordero, Javier ������������������������������������ P1136 Brenet, Marianne ����������������������������������������������P529 Bren-Mattison, Yvette �������������������������������������P1379 Brennan, Caroline H. ��������������������������������������P1079 Brenner, Chris ������������������������������������������������P1013 Brennwald, Patrick �����������������������������������������P1264 Breslin, Loretta �������������������������������������������������P146 Breslow, David K. ���������������������������������������������P164 Bresnick, Anne R. �������������������������������������������P2240 Bretscher, Anthony P. ���������������������������������������P466 Breuer, Denitra �����������������������������������������������P1597 Breuer, Gregory A. ������������������������������������������P2001 Breunig, Christopher ��������������������������������������P1893 Brewer, Bryson ����������������������������������������������� P1155 Brewer, Chris M. ���������������������������������������������P2481 Brewster, Jay L. ������������������������������������������������P671 Brezska, Hanna B. �������������������������������������������P965 Brian, Galletta J. �����������������������������������������������P206 Briceño, Fernanda ������������������������������������������P2307 Bridges, Andrew ���������������������������������������������P1446 Brigaud, Isabelle ���������������������������������������������P2216 Briggs, John A. ���������������������������������� P2088, P2091 Briggs, Meredith �����������������������������������������������P553 Brigstock, David R. �����������������������������������������P1656 Brill, Julie A. �������������������������������������������� P366,P509 Brilot, Axel F. ������������������������������������������� P808,P971 Brinkman, Eva K. ��������������������������������������������P2001 Brisken, Cathrin ������������������������������������������������P782 Britigan, Eric M. ������������������������������������������������P193 Broad, Amanda J. �������������������������������������������P1056 Broaddus, Russell R. ����������������������������������������P455 Brockdorff, Neil �����������������������������������������������P2043 Brodaczewska, Klaudia K. ������������������������������P1954 Broner, Esther C. ����������������������������������������������P336 Broniarczyk, Justyna �������������������������� P1604,P1605 Bronk, Gabriel ������������������������������������������������P2014 Bronner, Marianne E. ��������������������������� P762,P2375 Bronte-Tinkew, Dana ��������������������������������������P2151 Brooks, Rebecca ����������������������������������������������P388 Brooks III, Lionel ��������������������������������������������� P1134 Brose, Lotti A. �������������������������������������������������P1865 Bross, Peter ������������������������������������������������������P642 Brossier, Florence ������������������������������������������P1678 Brough, Carla �������������������������������������������������P2477 Broussard, Alex ����������������������������������������������P1370 Broussard, Joshua A. ������������������������� P1449,P2356 Brown, Cody F. �����������������������������������������������P2272 Brown, Dennis ������������������������������������������������P1597 Brown, James B. ��������������������������������������������P2300 Brown, Kristen D. �������������������������������������������P2405 Brown, Nicola ���������������������������������������������������P139 Brown, Nicolette P. �����������������������������������������P1205 Brown, Rebecca E. �������������������������������������������P704 Brown, Shyretha ���������������������������������������������P2437 Brown, Tanya ��������������������������������������������������P2378 Brown, William J. ��������������������������������������������P1293 Brownell, Sara E. �������������������������������������������� P6,P7 Browning, Anna C. ������������������������������������������P1662 Brownlee, Chris ������������������������������������������������P206 Brownlee, Christopher W. ���������������������������������P248 Broz, Miranda ������������������������������������������������� P1158 Brozena, Alexandra H. �������������������������������������P696 Brueckner, Martina �������������������������������������������P150 Bruehmann, Stefan ��������������������������������������������P85 Brugués, Jan �������������������������������� P240,P255, P985 Brumell, John H. ���������������������������������������������P2151 Brumfield, Alexandria M. ������������������������� P94, P419 Brummelkamp, Thijn �����������������������������������������P200 Brun, Yves ��������������������������������������������������������P798 Brunner, Damian ��������������������������������������������P2364 Bruses, Juan L. ����������������������������������������������P1044 Bruun, Kyle S. ��������������������������������������������������P958 Bruun, Kyle S. ������������������������������������������������P1712 Bruyere, Celine �����������������������������������������������P1738 Bryant, Annamarie T. ������������������������������������������P10

Bryant, David M. ����������������������������������� P318,P1720 Bryant, Zev �������������������������������������������������������P957 Bryce, Nicole S. ������������������������������������������������P905 Bu, Pengli ���������������������������������������������������������P267 Bubacco, Luigi ��������������������������������������������������P398 Bucci, John �����������������������������������������������������P1687 Bucciarelli, Elisabetta ���������������������������������������P204 Buchler, Nicolas E. �����������������������������������������P1035 Buchman, Vladimir �����������������������������������������P2366 Buchwalter, Abigail �����������������������������������������P1207 Buđa, Renata ���������������������������������������������������P186 Budi, Erine H. �������������������������������������������������P1587 Budnik, Bogdan ����������������������������������������������P1679 Budnik, Vivian �������������������������������������������������P2051 Budzinski, Christina ����������������������������������������������P1 Buechner, Matthew �������������������������������������������P627 Bufi, Nathalie ��������������������������������������������������P2219 Bugaj, Lukasz J. ��������������������������������������������� P1122 Bui, Brian ��������������������������������������������������������P1869 Bui, Minh ��������������������������������������������������������P2017 Buitrago, Andrea F. �������������������������������������������P406 Bulatov, Emil ��������������������������������������������������� P1116 Bulgari, Dinara ������������������������������������������������P1312 Bullard-Dillard, Rebecca �����������������������������������P853 Buller, Lisa ������������������������������������������������������P2003 Bunjes, Anne ��������������������������������������������������P1432 Buodko, Sergei P. �������������������������������������������P1499 Burch, Amelia �������������������������������������������������P2135 Burchard, Julja �����������������������������������������������P1365 Burckhardt, Christoph J. �����������������������������������P394 Burgess, David R. �������������������������������� P172,P1858 Burgess, Sean ������������������������������������������������P1869 Burgos, Patricia V. �������������������������������� P425,P1532 Burkard, Mark E. ����������������������������������� P193, P215 Burke, Brian �������������������������������������������� P377,P988 Burkhardt, Janis K. �����������������������������������������P1747 Burlingame, Alma L. �������������������������� P1420, P2121 Burnette, Dylan T���������������.P781,P925, P954,P1859 Burnetti, Anthony J. ����������������������������������������P1035 Burney, Waqas �����������������������������������������������P1633 Burns, Matthew ����������������������������������������������P1320 Burny, Claire ���������������������������������������������������P2366 Burridge, Keith �������������������������������������� P909,P1454 Burrus, Laura W. ��������������������������������������������P1372 Burtscher, Ashley ��������������������������������������������P1433 Bush, Jeffrey O. ����������������������������������������������P1585 Buske, PJ ���������������������������������������������������������P796 Bussolino, Federico ������������������������������������������P924 Bustamante, Hianara A. ���������������������������������P1532 Buster, Daniel W. ���������������������������������� P206,P1070 Bustos, Fernando J. ���������������������������������������P1366 Butler, Corey ������������������������������������������ P36, P2280 Butler-Browne, Gillian �������������������������������������P2236 Butt, Logan �������������������������������������������������������P341 Butt, Umar ����������������������������������������������������������P72 Butterfield, Hannah E. ������������������������������������ P1118 Buxeda, Rosa �������������������������������������������������������P3 Buxton, Iain L. �������������������������������������� P337,P1977 Byeon, JungHee ���������������������������������������������P1644 Byers, Stephen W. ������������������������������������������ P1131 Bykov, Yury S. ������������������������������������������������P2091 Byrne, Ronan �������������������������������������������������P1660 Byun, HeeSun ������������������������������������ P1093,P2205 Byun, Sung-Hyun �������������������������������������������P1567

C

C.P., Unnikannan ����������������������������������������������P370 Caballero, Manuel Y. ���������������������������P1187,P1688 Cabello, Simon �������������������������������������������������P242 Caberlotto, Elisa �����������������������������������������������P812 Cabernard, Clemens ��������������������������������������P1856 Cabral, Gabriela �����������������������������������������������P214 Cabrales, Pedro ���������������������������������������������P1702 Cabrera Vicens, Brenda ���������������������������������P2449 Cáceres, Mónica ��������������������������������������������P1437 Cáceres Cortés, Julio R. ��������������������������������P2452 Caceres Lluch, Monica �����������������������������������P2307 Cade, Jenny �����������������������������������������������������P986 Cadot, Bruno ����������������������������������������������������P988 Cagle, Patrice D. ����������������������������������������������P269 Cagnon, Valeria H. �����������������������������������������P2308 Cahoon, Cori ��������������������������������������������������P1869 Cai, Liang �������������������������������������������������������P1353

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Cai, Yin �������������������������������������������������������������P232 Cain, Ashlee ���������������������������������������������������P2341 Cain, Natalie �����������������������������������������������������P367 Calas, André ���������������������������������������������������P1785 Calderwood, David A. �������������������������������������P2249 Caldwell, Guy A. �����������������������������������������������P824 Caldwell, Kim A. �����������������������������������������������P824 Caldwell, Reese M. ������������������������������������������P738 Calidas, Deepika ����������������������������������������������P472 Caliskan, Elif B. ������������������������������������������������P526 Calizo, RhodoraCristina ���������������������������������P2141 Calle, Anna S. �������������������������������������������������P1946 CallierIV, Thomas P. ���������������������������������������P2163 Calvert, Meredith ���������������������������������������� P37,P38 Calvet, James P. �����������������������������������������������P157 Calvi, Alessandra ����������������������������������������������P988 Calvi, Brian R. ��������������������������������������������������P238 Calzada, Elizabeth �����������������������������������������P1338 Calzada-Mendoza, Claudia C. �����������������������P2452 Camacho, Maria M. ����������������������������������������P1621 Camdere, Gamze �������������������������������������������P1518 Cammarata, Garrett ���������������������������������������P1808 Campagnoli, Lauryn ���������������������������������������P2128 Campbell, A M. �����������������������������������������������������P8 Campbell, Andrew G. ������������������������������������� P1611 Campbell, Christopher S. ���������������������������������P194 Campbell, Sharon L. �����������������������������������������P909 Campbell, Shelagh D. ��������������������������������������P748 Campellone, Kenneth G. ���������������������� P935,P1734 Campelo, Felix �������������������������������������������������P416 Campillo, Clément ������������������������������������������P1710 Campos, Carl ���������������������������������������������������P288 Campos, Dilza B. ��������������������������������������������P2293 Campos, Matias ���������������������������������������������P1309 Campos, Silvana Gisele P. �����������������������������P1565 Camps, Jordi ����������������������������������������������������P241 Campsteijn, Coen ���������������������������������������������P404 Camuglia, Jaclyn M. �����������������������������������������P372 Canales, Jimena ���������������������������������������������P1437 Canman, Julie C. ����������������������������������� P168, P175 Cannon, Kevin ������������������������������������������������P1446 Cano-Cortina, Misael ��������������������������������������P2271 Canoll, Peter ��������������������������������������������������� P1102 Cano-Martínez, Agustina ��������������������������������P2482 Canuto, Leandro P. �������������������������������������������P636 Cao, Dan ��������������������������������������������������������P1792 Cao, Hong ��������������������������������������������������������P309 Cao, Ying ����������������������������������������������������������P151 Caobi, Allen ����������������������������������������������������P1627 Capallere, Christophe �������������������������������������P2402 Capasso, Teresa ���������������������������������������������P1428 Capel, Blanche �������������������������������������������������P790 Capetanaki, Yassemi ��������������������������������������P2371 Cappe, Benjamin ��������������������������������������������P2190 Cappell, Steven D. �����������������������������������������P1049 Cappione, Amedeo J. ���������������������������������������P332 Carabajal-Miotti, Claudia L. ����������������������������P1230 Caradonna, John ��������������������������������������������P2342 Carandang, Leslie ��������������������������������� P137, P138 Carbone, Catherine B. ��������������������������������������P596 Cardamone, Maria D. ������������������������� P1375,P1566 Cardenas, Areli �����������������������������������������������P2243 Carette, Jan E. �������������������������������������������������P559 Carisey, Alexandre F. ����������������������������������������P916 Carle, Christine M. ������������������������������������������P1988 Carlier, Marie-France ������������������������������������������P85 Carlson, Bradley A. ����������������������������� P1640,P2418 Carlson, Lars-Anders ������������������������� P2093,P2316 Carlton, Jeremy G. �������������������������������������������P497 Carmena, Mar ������������������������������������������������P1893 Carnell, Lucinda �����������������������������������������������P681 Carpenter, Austin S. ���������������������������������������P2404 Carpenter, Brandon ������������������������������������������P834 Carré, Manon �������������������������������������������������P2451 Carreno, Sebastien ����������������������������������������P1434 Carroll, Christopher W. ����������������������� P1219,P2019 Carrot, Guillemette �����������������������������������������P2135 Carson, Laura �����������������������������������������������������P28 Carson, Laura ��� P1494,P1542,P1917,P1918,P1922 Cartagena-Rivera, Alexander X. ���������������������P1458 Cartagenova, Luis ������������������������������������������P2136 Carter, Elisabeth A. �������������������������������������������P654 Carter, Hannah ����������������������������������������������� P1139

Carter, Lucas ����������������������������������������������������P788 Carter, Stephen D. ����������������������������������������������P30 Carter, Stephen P. ������������������������������������������P1840 Carvalho, Adriana B. ��������������������������������������P2293 Carvalho, Antonio Carlos C. ���������������������������P2293 Carvalho, Hernandes F. ����������������������������������P2459 Carvelli, Flavia L. �������������������������������������� P41,P501 Case, Lindsay B. ��������������������������������������������P1748 Casey, Amanda K. ������������������������������������������P1506 Casey, Carol A. �������������������������������������������������P435 Casler, Jason C. �����������������������������������������������P422 Cass, Julie ��������������������������������������������������������P801 Cassereau, Luke ������������������������ P333,P867, P1158 Cassimeris, Lynne ������������������������������������������P1507 Castellucci, Nevin ���������������������������������������������P900 Castle, Brian T. ������������������������������������� P132,P1805 Castle, Jordan ������������������������������ P305,P306, P723 Castracane, James ����������������������� P341,P601,P761 Castro, Lysandra ���������������������������������� P528,P1419 Caswell, Patrick ����������������������������������������������P1271 Catalan, Jose �������������������������������������������������P2185 Catane, Liora �������������������������������������������������� P1124 Catarino Marques Sousa, Paticia �������������������P1785 Cater, Sean ������������������������������������������������������P890 Catillon, Marie ������������������������������������������������P1719 Cato, Kathleen ������������������������������������������������P1959 Caudron, Fabrice ��������������������������������������������P1794 Caussinus, Emmanuel �����������������������������������P2364 Cavieres, Viviana ����������������������������������������������P425 Cavnar, Peter J. ������������������������������������������������P849 Cayre, Myriam ������������������������������������������������P2451 Cecchetelli, Alyssa D. ���������������������������������������P612 Cech, Tom ��������������������������������������������������������P863 Cederquist, Carly T. ���������������������������� P1375,P1566 Cejka, Cestmir ��������������������������������������������������P819 Cejkova, Jitka ���������������������������������������������������P819 Cekanaviciute, Egle ����������������������������������������P1639 Cerabona, Donna M. ����������������������������������������P217 Cerda, Oscar ������������������������������������� P1437, P2307 Cereghetti, Gea ������������������������������������������������P710 Cerikan, Berati ����������������������������������������������������P98 Cervero, Pasquale ������������������������������������������ P1711 Cerza, Decklan P. ���������������������������������������������P348 Cha, Pu-Hyeon �������������������������������������������������P278 Chabadel, Anne ��������������������������������������������������P95 Chabert, Rachel ���������������������������������������������P2402 Chacon, Jeremy M. ������������������������������������������P196 Chacón, Pablo ������������������������������������������������P1787 Chadwick, Jessica ������������������������������������������P2056 Chadwick, Richard S. �������������������������������������P1458 Chadwick, Sarah R. ������������������������������������������P706 Chae, Han- J. ������������������������������������� P1561,P2309 Chafe, Shawn C. ����������������������������������������������P321 Chagan, Jayshan ���������������������������������������������P906 Chai, Yongping �����������������������������������������������P1857 Chai, Chew ���������������������������������������������������������P19 Chaiboonchoe, Amphun ���������������������������������P1927 Chaikeeratisak, Vorrapon ����������������������� P800,P808 Chaiseha, Yupaporn ���������������������������������������P2441 Chakravarty, Kaushick ������������������������������������P1544 Chakravorty, Samya ���������������������������������������P2471 Chalasani, Madhavi L. ��������������������������������������P886 Chalker, Douglas L. ............................ P1013, P1988 Challa, Anil K. ���������������������������������������������������P844 Chalouni, Cecile M. ��������������������������������������������P63 Chambers, Kevin ����������������������������������������������P868 Chamma, Ingrid ����������������������������������������������P2280 Chan, Caleb ���������������������������������������������������P1239 Chan, Chi H. �����������������������������������������������������P806 Chan, Chieh-Wen �������������������������������������������P1926 Chan, Christina �������������������������������������������������P862 Chan, David C. �����������������������������������������������P2161 Chan, Ernest R. ����������������������������������������������P1648 Chan, Gordon K. ����������������������������������������������P272 Chan, Julie Y. ��������������������������������������������������P2399 Chan, Kin ������������������������������������������� P2435, P2460 Chan, Leslie J. ��������������������������������������������������P553 Chan, Michelle ������������������������������������������������P1566 Chan, Robin B. �������������������������������������������������P544 Chan, Shu N. ��������������������������������������������������P1513 Chandhoke, Surjit K. ��������������������������������������P1742 Chandra, Madeline ����������������������������������������� P1125 Chandra, Sreeganga S. ������������������������������������P400 Chandrasekar, Indra �����������������������������������������P385

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Chandrasekaran, Aravind �������������������������������P1709 Chandrasekaran, Vidya �������������������������� P355,P581 Chandris, Panagiotis ��������������������������������������P1364 Chanet, Soline ������������������������������������������������P1890 Chang, Albert ��������������������������������������������������P1278 Chang, Alvin ���������������������������������������������������P2240 Chang, Chi-Lun ������������������������������������������������P536 Chang, Chu-Yuan �������������������������������������������P1315 Chang, Eric �������������������������������������������������������P948 Chang, Eun-Ju ����������������������� P2430, P2431,P2432 Chang, Fred ��������������������������� P1795, P1858,P2217 Chang, Hao ���������������������������������������������������� P1170 Chang, Jeffrey T. ����������������������������������������������P541 Chang, Jen-Chien ������������������������������������������P2008 Chang, Jessica �������������������������������������������������P606 Chang, Kevin ����������������������������������������������������P978 Chang, Lin ������������������������������������������������������P2163 Chang, Shiun ����������������������������������������������������P708 Chang, Ting-Jung �������������������������������������������P2072 Chang, Yu-Chen ���������������������������������������������P1000 Chantarasinlapin, Praew ����������������������������������P552 Chapman, Dail E. ��������������������������������� P121,P1753 Chapman, Edwin R. ���������������������������������������P2064 Charaffedine, Rabab ��������������������������������������P1802 Charles, Emeric J. ��������������������������������������������P799 Charles-Orszag, Arthur �����������������������������������P2412 Charras, Guillaume ������������������� P604,P1080,P2260 Chartier, Francois ���������������������������������������������P582 Chaterji, Somali ����������������������������������������������P2285 Chatterjee Bhowmick, Diti ������������������������������P1297 Chattopadhyay, Rima �������������������������������������P2275 Chaturantabut, Saireudee ������������������������������P2137 Chau, Yeung Yeung ����������������������������������������P2288 Chaudhary, Natasha �����������������������������������������P419 Chaudhuri, Ovijit ����������������������������������� P606,P1487 Chaudry, Ghulam J. �����������������������������P1187,P1688 Chauhan, Vasudha �����������������������������������������P1713 Chavali, Arvind K. ���������������������������������������������P558 Chavrier, Philippe �������������������������������������������P1250 Cheerambathur, Dhanya K. ����������������������������P1902 Cheeseman, Iain M. ����������������������������� P202,P1780 Chellaiah, Meenakshi A. ���P897,P898,P1948,P1972 Chen, Anan ���������������������������������������������������������P88 Chen, Baohan ������������������������������������������������P2382 Chen, Bi-Chang ����������������������������������� P179, P1441 Chen, Carlos C. ������������������������������������������������P714 Chen, Chang-Jui ����������������������������������������������P347 Chen, Chi-Yuan ����������������������������������������������P1926 Chen, Christina Yingxian ����������������������������������P600 Chen, Christopher S. �������������������������������������� P1161 Chen, Chuan ����������������������������������������������������P360 Chen, Chun-Hao ����������������������������������������������P324 Chen, Elizabeth H����������������������������� .P2215, P2357 Chen, Geng-Yuan ��������������������������������� P120,P1751 Chen, Guang-Chao ����������������������������������������P2073 Chen, Helen ����������������������������������������P1025,P2113 Chen, Hsing-Hsung ����������������������������������������P1321 Chen, Hsin Yi ����������������������������������������������������P209 Chen, Hsin-Yu ���������������������������������������� P252,P253 Chen, Hui �������������������������������������������������������P2349 Chen, Hung-Yang ���������������������������������������������P616 Chen, James K. ������������������������������������������������P164 Chen, Janice S. ���������������������������������������������� P1180 Chen, Jianguo ��������������������������������������������������P969 Chen, Jian-Hua ����������������������������������������������P1667 Chen, Jiaxuan ������������������������������������������������P1074 Chen, JiLong ��������������������������������������������������P1620 Chen, Jing ������������������������������������������� P309, P2416 Chen, Jingjing �������������������������������������������������P1075 Chen, Jingrong ��������������������������������������� P236,P239 Chen, John �������������������������������������������������������P887 Chen, Joseph ���������������������������������������������������P314 Chen, Jun-Song ����������������������������������� P212,P1848 Chen, Kuan J. �������������������������������������������������P1427 Chen, Kunning �������������������������������������������������� P119 Chen, Li ����������������������������������������������� P421, 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AUTHOR INDEX Chen, Ruey-Hwa ����������������������������������������������P325 Chen, Ruju �����������������������������������������������������P1656 Chen, Sean ������������������������������������������������������P756 Chen, Sheng-hong �����������������������������������������P1083 Chen, Shengyao �����������������������������������������������P238 Chen, Show-Li ������������������������������������������������P1321 Chen, Steven ��������������������������������������������������P1999 Chen, Ting-Chun ������������������������������������ P252,P253 Chen, Vivian ���������������������������������������������������P1510 Chen, Wei Ting ������������������������������������� P524,P1345 Chen, Xian-Ming ���������������������������������������������P2416 Chen, Xiao ������������������������������������������������������P2142 Chen, Xin ���������������������������������� P221, P2435,P2460 Chen, Ying-Han ����������������������������������������������P1071 Chen, Yu ���������������������������������������������������������P2305 Chen, Yue ��������������������������������������������� P667,P2400 Chen, Yu-Hang �����������������������������������������������P2013 Chen, Yu-Ju ������������������������������������������������������P536 Chen, Yujun ����������������������������������������������������P1433 Chen, Yun ��������� P1462,P1468,P1496,P1698,P2241 Chen, Zhenlong ����������������������������������������������P1377 Chen, Zhilu �������������������������������������������������������P728 Chenchik, Alexander A. ����������� P1173,P2440,P2458 Cheney, Clarissa M. �����������������������������������������P852 Cheney, Richard E. �������������������������������� P950, P959 Cheng, Aaron T. ������������������������������������������������P392 Cheng, Delfine ����������������������������������������������������P31 Cheng, Fang �����������������������������������������������������P628 Cheng, Hsiao-Chi �������������������������������������������P1000 Cheng, Tak S. �������������������������������������������������P2155 Cheng, Tze-Yuan ������������������������������������ P872,P873 Cheng, Yun-Hsin ����������������������������������������������P548 Chenoweth, David M. �������������������������������������P1058 Cheriyath, Venugoapaln ���������������������������������P1737 Chernichenko, Natalya �������������������������������������P324 Chetty, Sundari �����������������������������������������������P2397 Chetyrkin, Sergei V. ����������������������������������������P1499 Cheuquemilla, Yorka I. �����������������������������������P1532 Chew, Jennifer ��������������������������������������������������P890 Chew, Teng-Leong ��������������������������������������������P953 Chew, Ting Gang. ������������������������������ P1853, P1745 Chew, Yuan Y. ������������������������������������������������P2415 Chi, Guang Fan ������������������������������������������������P823 Chi, Jen-Tsan Ashley ����������������������������������������P181 Chial, Heidi J. �������������������������������������������������P1379 Chiang, Tsai S. �������������������������������������������������P899 Chiang, Tsai C. �����������������������������������������������P1427 Chiang, Yue-Jen ���������������������������������������������P1000 Chiappetta, Austin M. �������������������������������������P2012 Chiaruttini, Nicolas �����������������������������������������P2094 Chiaverina, Giulia ���������������������������������������������P924 Chiba, Kyoko �����������������������������������������P115,P1304 Chien, Alexander ��������������������������������������������P1814 Chien, Chung-Liang �����������������������������������������P487 Chien, Jeremy ������������������������������������������������P1368 Chien, Ko-yi ������������������������������������������������������ P115 Chien, Wen-Hua �����������������������������������������������P697 Chikte, Prasad ������������������������������������������������P1994 Childers, W. S. ������������������������������������������������P2184 ChildVI, Myron ��������������������������������������������������P792 Chin, Cheen F. ����������������������������� P251,P840,P2415 Chin, Harvey ���������������������������������������������������P1854 Chin, Samantha M. �����������������������������������������P2472 Chinnapen, Daniel J. ��������������������������������������P1357 Chino, Takahiro �����������������������������������������������P2424 Chintamen, Sana ����������������������������������������������P617 Chittiboyina, Shirisha ����������������������������������������P334 Chitwood, Patrick J. ������������������������������������������P426 Chiu, Cathleen ����������������������������������������������������P40 Chiu, Chi-Li ���������������������������������������������������������P68 Chiu, Po-Yuan ��������������������������������������������������P616 Chmatal, Lukas ������������������������������������ P249,P1063 Chnag, Ya-Chu �����������������������������������������������P1000 Cho, Chang-Won ����������������������������������������������P549 Cho, Eui-Sic ���������������������������������������������������P1581 Cho, Hana �������������������������������������������� P771,P2370 Cho, Hyunji �����������������������������������������������������P2398 Cho, Kelvin �����������������������������������������������������P1674 Cho, Sangkyun �������������������������������������������������P600 Cho, Soo-Na ����������������������������������������� P677,P2413 Cho, Yong G. ��������������������������������������������������P1649 Cho, Yong-Hee �������������������������������������������������P278 Cho, Yun Ju ������������������������������������������������������P856 Choe, Seung H. ����������������������������������������������P2285

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Choi, Bongkun ����������������������� P2430, P2431,P2432 Choi, Cheolwon ��������������������������������� P1091, P1708 Choi, Eun K. ���������������������������������������������������P1094 Choi, Hee-Jeong ����������������������������������������������P825 Choi, Hee June �������������������������������������������������P107 Choi, Hwajung ������������������������������������������������P1581 Choi, Hyungwon ���������������������������������������������P1214 Choi, Ji-Ae �������������������������������������������� P677,P2413 Choi, Jieun �������������������������������������������������������P294 Choi, John M. �����������������������������������������������������P68 Choi, Jong Ho ���������������������������� P809,P1435,P1436 Choi, Kang-Yell ������������������������������������� P278,P2448 Choi, Kate ���������������������������������������������������������P933 Choi, Kyeong Sook ����������������������������������������P1095 Choi, Sehee ����������������������������������������������������P2448 Choi, Suin �������������������������������������������������������P2133 Choi, Yean-Jung ���������������������������������������������P2480 Choi, Yun-jung ������������������������������������������������P1514 Choi, Yusun ��������������������������� P1152, P1932, P1933 Chollet, Christel ����������������������������������������������P2302 Chong, Jessica X. ��������������������������������������������P945 Choquet, Daniel ���������������������������������� P2090,P2280 Choquet, Karine �������������������������������������������������P52 Chou, Jonathan ����������������������������������������������P1964 Chou, Tom ������������������������������������������������������P2401 Chou, Tsui-Fen �����������������������������������������������P1533 Choudhuri, Kaushik ������������������������������������������P554 Chow, Carson C. �������������������������������������������� P1176 Chow, Sheung Ching ��������������������������������������P2276 Chow, Tianna ����������������������������������������������������P333 Chow, Tracy T. ������������������������������������������������P1999 Chowdhury, Nobel ������������������������������������������P1737 Chozinsk, Tyler �����������������������������������������������P1664 Christensen, Jenna R. ���������������������������� P895,P907 Christensen, Ryan ����������������������������������������������P44 Christensen, Søren T. ��������������������������� P146,P1839 Christenson, Wayne ���������������������������������������P1696 Christian, Keith A. �������������������������������������������P1273 Christofk, Hearther �����������������������������������������P2392 Chu, Dan ��������������������������������������������������������P1869 Chu, Diana S. ���������������������������������������������������P255 Chu, Emily Y. ����������������������������������������������������P778 Chu, Felix ���������������������������������������������������������P999 Chu, Ling-yun ������������������������������������������������� P1178 Chu, TonyLH ����������������������������������������P1151,P2113 Chu, Vi ������������������������������������������������������������P1956 Chu, Yu-Ting ������������������������������������������� P252,P253 Chua, Michael D. ��������������������������������������������P1722 Chuang, Mei-Chun �����������������������������������������P1451 Chuang, Yichen ����������������������������������������������P1616 Chudalayandi, Prakash ��������������������� P1515, P1517 Chug, Hema ���������������������������������������������������P1666 Chugh, Mayank ����������������������������������������������P1801 Chukwurah, Evelyn E. ��������������������������������������P676 Chun, Kun ��������������������������������������������������������P825 Chung, Chang Y. ����������������������������������������������P443 Chung, Dayoung ����������������������������������������������P443 Chung, Eunkyung ������������������������ P461,P823,P2380 Chung, Hui-Min �������������������������������������� P532,P534 Chung, Jean K. �������������������������������������������������P598 Chung, Joyce J. ����������������������������������������������P1988 Chung, Mingyu �������������������������� P785,P1049,P1429 Chung, Minwhang ��������������������������������������������P717 Chung, Si-Yin �������������������������������������������������P1379 Chuong, Cheng-Ming ��������������������� P40,P616, P760 Cianfrocco, Michael ����������������������������������������P1765 Cieslinski, Konstanty A. ����������������������������������P1914 Cifuentes, Manuel ������������������������������� P514, P1007 Cimini, Daniela ��������������������������������������� P190,P241 Cimino, George ������������������������������������������������P277 Cisneros-Vega, Bulmaro �������� P1231,P2023,P2040, �������������������������������������������������P2041,P2042,P2303 Cisternas, Pedro ��������������������������������������������� P2114 Citron, Rose �����������������������������������������������������P990 Clark, Abbot F. ������������������������������������ P1498,P2447 Clark, Andrew G. �������������������������������������������� P1154 Clark, Kristy ���������������������������� P1340, P1341,P2166 Clark, Peter M. �����������������������������������������������P2392 Clark, Richard A. ��������������������������������������������P1503 Clarke, Duncan J. ���������������������������������������������P196 Clarke, Nicholas I. ����������������������� P32,P1271,P2089 Clarke, Paul R. �����������������������������������������������P1213 Clarke, Rosie ��������������������������������������������������P1676 Claverie, Marie-Charlotte �������������������������������P1856

Claypool, Steven M. ��������������������������� P1338,P2164 Clayton, Dennis R. �������������������������������������������P442 Clayton, Joseph E. ��������������������������������� P57,P1088 Cleetus, Augustine �������������������������������������������P963 Clement, Cristina C. ���������������������������������������P1414 Clement, Laurence �������������������������������������������P848 Clements, Mary Ann �����������������������������������������P820 Clemett, Simon J. �������������������������������������������P2238 Clendenon, Sherry G. �������������������������������������P1653 Cleveland, Don W. �������������������������������� P203,P1062 Clifford, Coleman G. �����������������������������������������P612 Clinton, James ��������������������������������������������������P877 Clister, Terri �������������������������������������������������������P591 Cloatre, Thomas ���������������������������������������������P2216 Clovis, Yoanne M. �������������������������������������������P2464 Cluett, Edward B. ���������������������������������������������P551 Clutario, Kevin M���������������������������������� P208, P1037 Coalson, Rob ��������������������������������������������������P2037 Codding, Sara ������������������������������������������������P2055 Codega, Paolo ��������������������������������������������������P288 Coelho, Nuno M. ����������������������������������������������P652 Coelho, Priscila O. ������������������������������������������P1401 Cohen, Allison L. ��������������������������������������������P2419 Cohen, Andrew R. ����������������������������������������������P48 Cohen, Daniel J. ���������������������������������������������P1466 Cohen, Sarah �����������������������������������������������������P48 Cohen, Shenhav ���������������������������������������������P2478 Cohen-Fix, Orna ����������������������� P369,P2146, P2157 Cohn, Stanley A. ���������������������������������������������P2251 Coker, Heather �����������������������������������������������P2043 Cole, Candace ������������������������������������������������P1612 Cole, Douglas G. ��������������������������������������������P1614 Cole, Nelson B. ����������������������������������������������P1268 Coleman, Bradley I. ����������������������������������������P2069 Coles, Cassandre �������������������������������������������P1377 Colicino, Erica G. ����������������������������������������������P592 Collares-Buzato, Carla B. ����������������������� P562,P636 Coller, Hilary A. ����������������������������������������������� P1190 Collier, Eleanor ���������������������������������������������������P54 Collins, Caitlin �������������������������������������������������P1464 Collins, Carol M. ���������������������������������������������P2021 Collins, Catherine A. ���������������������������������������P1305 Collins, John ���������������������������������������������������P2144 Collins, Kerrie B. ��������������������������������� P1491,P2187 Collins, Mary A. ������������������������������������������������P372 Collura, Vincent ������������������������������������������������P866 Colmenares, Serafin U. ����������������������������������P1987 Colo, Georgina P. �����������������������������������������������P98 Colognato, Holly ���������������������������������������������P1825 Colombi, Paolo �����������������������������������������������P1208 Colón-Ramos, Daniel A. ������������������������� P44,P2136 Colton, Mariah ������������������������������������������������������P9 Combes, Guillaume ����������������������������������������P1909 Comerci, Colin J. �������������������������������� P1663,P1672 Comlekci, Emre ������������������������������������������������P282 Commander, Rachel �����������������������������������������P312 Compton, Duane A. ��������������������� P192, P199, P231 Comstra, Heather S. ���������������������������������������P1289 Comunale, Franck ������������������������������������������P1250 Comuzzi, Brendan ��������������������������������������������P401 Comyn, Sophie ������������������������������������������������� P711 Conacci-Sorrell, Maralice ���������������������������������P292 Condeelis, John S. ���������������������� P341,P601,P1136 Condie, Brian G. �������������������������������������������������P64 Condon, Brett M. ����������������������������������������������P414 Cong, Xiaofei ���������������������������������������� P820,P2426 Conkar, Deniz �������������������������������������������������P1823 Conley, Jami ���������������������������������������������������P1776 Connacher, MaryKatherine T. �������������������������P1430 Connell, Marisa ���������������������������������������������� P2113 Connolly, Melissa ��������������������������������������������P1693 Conover, Gloria M. �����������������������������������������P1717 Conover, Justin L. �������������������������������������������P1241 Conti, Mary A. �������������������������������������������������P1712 Conway, Daniel E. ������������������������������������������P1465 Cook, Brian D. ������������������������������������ P1789,P1795 Cook, Gregory ������������������������������������������������P1006 Cook, Jeanette G. ������������������������������������������P1898 Cook, Laurie B. �����������������������������������������������P2209 Cook, Peter J. �������������������������������������������������P1968 Coombes, Courtney �����������������������������������������P142 Coombs, Daniel ������������������������������������������������P933 Cooper, Anthonya �������������������������������������������P2202 Cooper, John A. ����������������������������������� P912, P2423

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Cooper, Katelyn M. ����������������������������������������� P6,P7 Cooper, Kim ����������������������������������������������������P1626 Cooper, Kimbal E. ������������������������������������������P2263 Cooper, Lee ������������������������������������������������������P312 Cooper, Robert J. �������������������������������������������P2405 Cooper, Roshni �������������������������������������������������P485 Copeland, John W. �����������������������������������������P1838 Copeland, Sarah J. �����������������������������������������P1838 Corbett, Kevin D. ��������������������������������������������P1871 Corbo, Christopher �������������������������������������������P259 Cordeiro, Ciro �������������������������������������������������P1598 Cordelières, Fabrice ���������������������������������������P1486 Corella, Alexandra ������������������������������������������P1957 Cork, Gentry K. ���������������������������������������������������P25 Cormier, Olga �������������������������������������������������P1072 Cornejo, Victor H. �������������������������������������������P1309 Cornell, Brett ����������������������������������������������������P491 Corney, David C. �������������������������������������������� P1190 Corona, Carlo ���������������������������������������������������P493 Corrales-Diaz Pomatto, Laura ������������ P1512,P1523 Correia, Maria S. ��������������������������������������������P1274 Correia, Sandra ����������������������������������������������P1448 Cortes, Daniel B. ��������������������� P1850,P1903,P1905 Cortés, Gladys T. ��������������������������������������������P1610 Cortés, Juan Carlos G. �����������������������������������P2099 Cortes-Reynosa, Pedro ���������������������� P1440,P1477 Cosgel, Adem �������������������������������������������������P1391 Costa, Elizabeth A. �������������������������������������������P506 Costantino, Santiago ������������������������������������������P52 Costes, Sylvain V. �������������������������������������������P1987 Coto, Doris �������������������������������������������������������P479 Coudrier, Evelyne ��������������������������������� P499,P1447 Coughlin, Arielle C. �����������������������������������������P1749 Coumans, Bernard �����������������������������������������P2343 Counihan, Jessica L. ��������������������������������������P1530 Cousin, Hélène �����������������������������������������������P1560 Cousins, Emily ��������������������������������������������������P480 Cousins, Henry �����������������������������������������������P1570 Coussens, Lisa M. ������������������������������������������ P1158 Couthouis, Julien ��������������������������������������������P2158 Coutinho, Kester ���������������������������������������������P1475 Couturier, Etienne ������������������������������������������� P2115 Couturier, Nathalie ������������������������������������������P2366 Couve, Andres ������������������������������������������������P1309 Coverley, Dawn ����������������������������������������������P2043 Covert, Markus W. ��������������P67,P740,P1617,P1629 Cox, Dan ��������������������������������������������������������P2135 Cox, Jeffery S. ��������������������������������������������������P802 Cox, Jordan ����������������������������������������������������P1006 Cox, Liza L. ������������������������������������������������������P778 Cox, Nathan J. ��������������������������������������������������P414 Cox, Timothy C. ������������������������������������������������P778 Coy, Brandon ����������������������������������������������������P635 Coyaud, Étienne �����������������������������������������������P321 Coyle, Max ���������������������������������������������������������P17 Craig, Erin M. ���������������������������������������������������P974 Cram, Erin J. �������������������P612,P1394,P1744,P2175 Crapo, Ammon �����������������������������������������������P1020 Crawford, Robert W. ��������������������������� P1631,P1633 Crawley, Scott W. ���������������������������������������������P954 Crespo, Isaac �������������������������������������������������P1541 Crest, Justin ���������������������������������������������������P1865 Criado-Hidalgo, Ernesto �����������������������������������P729 Crish, James F. ����������������������������������������������� P1102 Crissman, Jonathan ���������������������������������������P2422 Croisier, Marie ��������������������������������������������������P139 Croizier, Cindy ��������������������������������������������������P865 Crooke, Stanley T. �������������������������������� P410,P1240 Crovace, Murilo ������������������������������������������������P817 Crowder, Marina E. ��������������������������� P4,P12, P1015 Crowe, Olivia ����������������������������������������������������P749 Crucian, Brian E. ��������������������������������������������P2238 Crupi, Mathieu J. �������������������������������������������� P1121 Cruz, Kaila J. ����������������������������������������������������P483 Cruz, Leilani ���������������������������������������������������P1462 Cruz, Marco ����������������������������������������P1060, P1164 Cubano, Luis A. �� P276,P1923,P1949,P1974,P1975 Cuentas-Condori, Andrea A. ���������������������������P2124 Cuevas, Lena M. ����������������������������������������������P403 Cui, Bianxiao ������������������������������������������������������P54 Cui, Min ����������������������������������������������������������P1041 Cui, Wenhong ���������������������������������������������������P413 Cui, Yuanyuan ������������������������������������������������P2474 Culfa, Efraim ���������������������������������������������������P1823

Cullen, Paul J. ������������������������������������������������P2179 Cullen, Valerie ������������������������������������������������P2462 Cumbo, Troy �������������������������������������������������������P57 Cunha, Paula M. ���������������������������������������������P1929 Cunningham, Kathleen �����������������������������������P2035 Cunningham, Kirsten D. ���������������������������������P2417 Cupp, Timothy D. ����������������������������������������������P476 Curiel, Fernando R. ����������������������������������������P2134 Cuthbert, Jocelyn M. ����������������������������������������P345 Cutillas, Pedro R. �������������������������������������������P1079 Cutrale, Francesco ���������������������������������������������P68 Cybulski, Jim ������������������������������������������������������P17 Cyert, Martha S. ���������������������������������������������P1400 Cyr, Daniel G. ��������������������������������������� P791,P1592 Czarnecka, Anna M. ���������������������������������������P1954 Czarnecki, Peter G. ������������������������������������������P167 Czudnochowski, Nadine ��������������������������������� P2411

D

Daaka, Yehia �������������������������������������� P1255,P1983 Daeden, Alicia ������������������������������������������������P1803 Dagdas, Yavuz S. ������������������������������������������� P1180 Daggubati, Vikas ��������������������������������������������P1037 Daghsni, Marwa ���������������������������������������������P1044 Dagliyan, Onur �������������������������������������������������P719 Dahia, Chitra L. ����������������������������������������������P1580 Dahl, MaryBeth �����������������������������������������������P1013 Dahl, Peter J. ��������������������������������������������������P2064 Dahlberg, Lina L. �������������������������������������� P9,P1529 Dai, Aguang ������������������������������������������������������P997 Dai, Bing �����������������������������������������������������������P847 Dai, Jianli ����������������������������������������������������������P413 Dai, Jin �����������������������������������������������������������P1010 Daigle, Gavin ��������������������������������������������������P2035 Dalaker, Evan �������������������������������������������������P1318 Dalal, Yamini ����������������������������������������� P353,P2017 Dale, Ian W. ����������������������������������������������������P1481 D’Alessandro, Alec �����������������������������������������P1203 Dalghi, Marianela G. �����������������������������������������P442 Dalton, Nancy �������������������������������������������������P2266 Dambournet, Daphne ���������������������������������������P392 D’Ambrosio, Nicole �����������������������������������������P1203 Dameron, Marisa �������������������� P1340, P1341,P2166 Damler, Erica ��������������������������������������������������P2126 Dammermann, Alexander ��������������������� P214,P1824 Dancel-Manning, Kristen ����������������������������������P504 Danella, Erika �������������������������������������������������P1318 Dang, Brandon T. ��������������������������������������������P1915 Dang, Chi ������������������������������������������������������� P1170 DAngelo, William A. ��������������������������� P2382, P2384 Dang-Lawson, May ������������������������������������������P933 Dani, Adish �����������������������������������������������������P1358 Daniel, Emeline ������������������������������������������������P765 Daniel, Heather N. ��������������������������������������������P546 Daniels, Christine N. �����������������������������������������P454 Danielson, Keith G. ����������������������������������������P1229 Danielsson, Frida ��� P507,P508,P623,P1128,P1782 Dantas, Tiago J. ���������������������������������������������P1815 Danuser, Gaudenz ��������������������������������� P394,P719 Daoud, Sayel ��������������������������������������������������P1927 D’Archivio, Simon �������������������������������������������P1064 D’Arc Oliveira, Suellen �����������������������������������P1377 Dardick, Joseph M. �������������������������������������������P174 DaRocha-Azevedo, Bruno ��������������������������������P597 Darris, Carl E. �������������������������������������������������P1499 Dartigues, Peggy �������������������������������������������� P1153 Das, Amit ����������������������������������������������������������P937 Das, Anupam ��������������������������������������������������P1331 Das, Maitreyi ��������������������P447,P471,P1849,P1867 Das, Moumita �������������������������������������������������P1535 Das, Ravi ��������������������������������������������������������P2135 Das, Soumita �������������������������������������� P1280,P1616 Das, Subhadeep ��������������������������������������������� P1115 Das, Tuhin ������������������������������������������������������P1027 Dasbiswas, Kinjal ���������������������������������������������P953 Daseke, John �������������������������������������������������P2438 daSilva, Evelin C. �������������������������������������������P1931 DaSilva, Fabio ������������������������������������������������P2476 daSilva, Mariana B. ����������������������������������������P1500 Dasso, Mary ���������������������������������������������������P1210 Datta, Nabanita S. ������������������������������������������P1090 Daubriac, Julien ������������������������������������������������P665

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Daudelin, Timothy ������������������������������������������� P1411 Daum, John R������������������������������������� .P230, P1019 Davì, Valeria ��������������������������������������������������� P2115 David, Larry ����������������������������������������������������P1365 Davidovich, Pavel ������������������������������������������� P1116 Davids, Mariska ����������������������������������������������P1281 Davidson, Andrew J. �����������������������������������������P105 Davidson, Ben ������������������ P336,P338,P1124,P1146 Davidson, Lance A. ������������������������������������������P767 Davidson, Michael W. �����������P48,P593,P917,P1471 Davidson, Reshma �������������������������������������������P188 Davies, Brian A. ����������������������������������������������P2150 Davies, Tim �������������������������������������������� P168, P175 Davis, Christine A. ����������������������������������������������P46 Davis, Daniel M. �����������������������������������������������P916 Davis, Eric M. ���������������������������������������������������P559 Davis, Floyd ����������������������������������������������������P2434 Davis, Gabrielle ���������������������������������������������� P1125 Davis, Graeme W. �����������������������������������P69,P2311 Davis, Jamaine S. ������������������������������������������ P1130 Davis, Jason ���������������������������������������������������P2166 Davis, Justin L. �����������������������������������������������P1727 Davis, Roger J. ������������������������������������������������� P115 Davis, Simon J. ����������������������������������������������P2193 Davis, Taylor �����������������������������������������������������P400 Davis, Trisha N. ���� P971,P972,P1879,P1897,P1912 Davis, Tyler L. �������������������������������������������������P1633 Davis-Roca, Amanda C. ���������������������������������P1906 Dawicki-McKenna, Jennine M. �����������������������P1063 Dawson, Scott C. ��������������������������������������������P1818 Day, Charles A. �������������������������������������������������P222 Dayam, Roya M. ������������������������������������� P396,P805 De Aguero, Joshua L. �������������������������������������P2294 Dean, David A. �����������������������������������������������P2103 Dean, Ziah ��������������������������������������������������������P735 Debacq-Chainiaux, Florence ��������������������������P1354 De BarrosSantos, Camilla ��������������������������������P500 De Belly, Henry �������������������������������������������������P376 Debnath, Jayanta ������������������������������ P2077,P2319, ..................................................P2083,P2324,P2333 Deborde, Sylvie .. ���������������������������������������������P324 de Bruin, Rob A. ���������������������������������������������P1050 De Camilli, Pietro ��������������������P55,P535,P537,P538 Dechant, Reinhard �������������������������������������������P710 Dechassa, Mekonnen �������������������������������������P1056 Decker, Franziska ����������������������������������� P732,P985 Decker, JaLisa ������������������������������������������������P2267 Deckwirth, Vivi ������������������������������������������������P1980 De Crescenzo, Angelo ������������������������������������P2125 Dedham, Deanna �������������������������������������������P1667 Dedhar, Shoukat �����������������������������������������������P321 De Falco, Tony ��������������������������������������������������P790 De Felice, Mialy ��������������������������������������������������P67 De Francesco, Alicia ���������������������������������������P1314 Deger, Jennifer �����������������������������������������������P1531 deGorter, David J. ������������������������������������������P2253 Deguchi, Takahiro �����������������������������������������������P73 De Hoyos, Cheryl L. ���������������������������������������P1240 De Jesus, Elfie �����������������������������������������������P1580 Dekker, Cees ��������������������������������������������������P2003 De Kloe, James ��������������������������������������������������P21 De Koninck, Yves �����������������������������������������������P52 De la cour, Delphine �����������������������������������������P445 de la Fuente, Erwin ����������������������������������������P1262 Del Alamo, Juan C. �������������������� P729,P1489,P2214 de la Rosa, Gabriel �������������������������������������������P621 Delevoye, Cédric ���������������������������������� P499,P1288 Deleyrolle, Loic P. �������������������������������������������P1951 Delfin, Dawn A. �����������������������������������������������P2294 Delgado, Yamixa ��������������������������������P1113, P1943 Delgado Cruz, Mariel �������������������������� P1291,P2057 Delgado-Cruzata, Lissette ������������������������������P1961 Dell, Alison L. ��������������������������������������������������P1588 Della Flora Nunes, Gustavo ���������������������������P2172 Dell Angelica, Esteban C. �������������������������������P1270 Dellibovi-Ragheb, Teegan A. ��������������������������P1071 Delos Santos, Ralph C. ����������������������� P396, P1085 de Lourenço, Caroline C. �������������������������������P2468 Delrow, Jeffrey J. ����������������������������������������������P788 Del Signore, Steven J. ������������������������������������P1253 De Luca, Jennifer G. ��������������� P1055,P1056,P1895 Del Valle, Juan ���������������������������������������� P275,P708 De Magistris, Paola ����������������������������������������P1216

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AUTHOR INDEX De Maziere, Ann M. ������������������������������������������P999 Demieville, Jennifer ����������������������������������������P1651 Demkovich, Andrey Y. ������������������������������������� P1177 Denais, Celine M. ���������������������������������������������P375 Denarier, Eric ��������������������������������������������������P1794 Denat, Laurence ���������������������������������������������P2302 DenBesten, Pamela ���������������������������������������P2120 Denetclaw, Wilfred F. ��������������������������������������P2355 Deng, Peter ������������������������������������������������������P884 DeNies, Maxwell ����������������������������������� P390,P2096 Denijs, Laurence ��������������������������������������������P2343 Denisin, Aleksandra K. �����������������������������������P1695 Dennis, Megan K. ���������������������������������������������P499 Dent, Erik W. ������������������������������������������ P489,P495 Dentler, William L. ��������������������������������������������P993 Denu, Ryan A. ��������������������������������������������������P215 Deppmann, Christopher ���������������������������������P1301 DeQueiroz, Rafaela M. �����������������������������������P1368 Deretic, Jovana ����������������������������������������������P1029 Derivery, Emmanuel ���������������������������������������P1803 Derman, Alan I. �����������������������������������������������P1735 Dernburg, Abby F. ���������P1871,P1873,P1874,P1875 DeRossett, Lauren ���������������������������������������������P70 DeRossi, Sylvain ��������������������������������������������P2248 Dery, Marc-Andre ���������������������������������������������P678 Derynck, Rik ���������������������������������������������������P1587 deSá, Felipe ���������������������������������������������������P2287 Desai, Arshad B. P194,P1038,P1076,P1546,P1855, ������������������������������������������������������������ P1863,P1902 Desai, Neil ��������������������������������������������������������P883 Desai, Pujan ���������������������������������������������������P1700 Desai, Rajiv M. �����������������������������������������������P1487 DeSantis, Morgan E. ��������������������������������������P1765 Deshmukh, Abhijit S. ��������������������������������������P1594 Deshong, Alison J. ������������������������������������������P1033 Deshpande, Girish ��������������������������������������������P213 Deshpande, Ojas ��������������������������������������������P2346 DeSimone, Jessica A. ��������������������������������������P192 De Souza, Alann T. �������������������������������������������P817 De Souza, Rebecca �����������������������������������������P884 De Souza Santos, Marcela �����������������������������P2414 Destaing, Olivier ���������������������������������������������P2289 Detmar, Michael ���������������������������������������������P2310 Dettmer, Ulf ����������������������������������������������������P1323 Deutscher, Roswell C. ������������������������������������P2066 DeVault, Laura ������������������������������������������������P1319 de Vere White, Ralph ���������������������������������������P277 De Waard, Michel �������������������������������������������P1044 De Wald, Stephanie ����������������������������������������P1023 Dewan, Aaraf ��������������������������������������������������P2475 Dewan, Kalyan K. �������������������������������������������P2418 Dewey, Evan B. ������������������������������������������������P246 Dewulf, Melissa ����������������������������������������������P2236 Dey, Tuli ���������������������������������������������������������� P1140 Dhall, Atul ���������������������������������������������������������P341 Dhanda, Aaron S. �������������������������������������������P1721 Dhanyasi, Nagaraju ����������������������������������������P1470 Dhar, Suman K. �����������������������������������P1197,P1594 Diamond, Paige ���������������������������������������������� P1195 Dias, Wagner B. ���������������������������������������������P1368 Diasio, Robert B. �������������������������������������������� P2011 Diaz, Catalina �������������������������������������������������P2307 Diaz, Roberto E. ���������������������������������������������P1334 Díaz, J.Fernando ��������������������������������������������P1787 Diaz-Aragon, Ricardo �������������������������������������P1477 Diaz-Rohrer, Barbara ���������������������������������������P543 Diaz-Rohrer, Blanca B. ������������������������� P544,P1355 DiBello, Joseph ����������������������������������������������P1203 DiBenedetto, Emmanuele ������������������������������P1536 diBlasio, Laura ��������������������������������������������������P924 Dicicco, Aurélie �����������������������������������������������P1444 Dickey, Burton F. ���������������������������������������������P2065 Dickinson, Daniel J���������������������������������� .P66, P450 Dickman, Dion ������������������������������������������������P2135 Dickson, Eamonn J. �����������������������������������������P555 Dickson, Lindsey ����������������������������������������������P432 Didonna, Alessandro ��������������������������������������P1639 Diehl, Michael R. ������������������������������������������������P96 Diehl, Paul ������������������������������� P1173,P2440,P2458 Diemen, Ferdy v. ����������������������������������������������P200 DiFiore, PierPaolo ������������������������������������������P1528 DiFlorio, Damian N. ����������������������������������������P1097 Diggins, Nicole �����������������������������������������������P1246 Digilio, Laura ��������������������������������������������������P1247

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Dillard, Pierre ����������������������������������������������������P929 Dilsaver, Matthew R. ��������������������������������������P2022 DiMario, Patrick J. ������������������������������ P1222,P1223 Dimchev, Georgi �������������������������������������������������P85 Dimitrov, Ariane ����������������������������������������������P2302 Dimitrov, Dimitar ���������������������������������������������P1308 Ding, Baojin ����������������������������������������������������P2051 Ding, Xueqin ���������������������������������������������������P2392 Ding, Yi-Shan ����������������������������������������� P252,P253 Ding, Yuqiang �������������������������������������������������P2376 Dinges, Nadja �������������������������������������������������P1994 Dingli, Florent �������������������������������������������������P1073 Dinner, Aaron ����������������������������������������������������P919 Dinshaw, Kayla M. �������������������������������� P640,P2367 Dionne, LaiKuan �����������������������������������������������P155 Dionne, Ugo �����������������������������������������������������P584 Di Paolo, Gilbert �����������������������������������������������P544 Di Pietro, Erminia �������������������������������������������P2151 Di Pietro, Santiago M. ������P384,P403,P1273,P1276 Discher, Dennis E. ��������������������� P600,P1141,P1228 Ditlev, Jonathon A. �������������������������������� P931,P1748 Dittman, Jeremy ��������������������������������� P1316,P2213 Dittmar, Mark ��������������������������������������������������P1701 Divita, Gilles �����������������������������������������������������P883 Dixon, Darlene �������������������������������������� P528,P1419 Diz-Muñoz, Alba ���������������������������������� P617, P2252 Djakovic, Stevan ���������������������������������������������P1916 Djander, Selma �������������������������������������������������P866 Dmitrieff, Serge �����������������������������������������������P1448 Do, Duc ������������������������������������������������������������P890 Dobrinskikh, Evgenia ����������������������������������������P530 Dobro, Megan J. �����������������������������������������������P832 Dobrucki, Jerzy �����������������������������������������������P1238 Dobrzynski, Maciej �������������������������������������������P717 Docampo, Roberto ����������������������������� P1598,P2169 Dodd, Rebecca J. ���������������������������������������������P587 Dodonova, Svetlana O. ����������������������������������P2091 Doebley, Anna-Lisa �������������������������������������������P746 Doering, Tamara L. �����������������������������������������P2423 Doganli, Canan �����������������������������������������������P1589 Doggett, Teresa ������������������������������������������������P368 Dogniaux, Stephanie �������������������������� P2219,P2220 Dogra, Prashant ���������������������������������������������P1306 Dohi, Taeko �������������������������������������������������������P379 Dohle, Daniel S. �����������������������������������������������P346 Dohmae, Naoshi ���������������������������������������������P2052 Dohn, James ��������������������������������������������������P1052 Dohr, Gottfried ������������������������������������������������P2279 Dolgorsuren, Buyannemekh �����������������������������P663 Dolinski, Kara �������������������������������������������������P1545 Dolios, Georgia �����������������������������������������������P2422 Dolman, Nicholas J. �����������������������������������������P868 Domingues, Lia ������������������������������������������������P499 Dominguez, Eddie ��������������������������������������������P173 Dominguez, Roberto ��������������������������������������P1445 Dominova, Irina N. ������������������������������������������P2381 Domke, Lisa M. ����������������������������������������������P2269 Domloge, Nouha ��������������������������������������������P2402 Donaldson, Julie G. ������������������������������������������P773 Donaldson, Julie ����������������������� P965,P1260, P1261 Donaldson, Michaela ����������������������������������������P293 Donaldson, William �������������������������������������������P872 Dong, Dawei W. ����������������������������������������������P1387 Dong, Haidong �����������������������������������������������P1402 Dong, Ming ������������������������������������������������������� P112 Dong, Qianhua �����������������������������������������������P2013 Dong, Rui ���������������������������������������������������������P538 Dong, Xiu Rong ����������������������������������������������P2481 Dong, Yongming ���������������������������������������������P1316 Donlin-Asp, Paul G. ����������������������������������������P2017 Donnelly, Roarke L. ������������������������������������������P841 Doonan, John �������������������������������������������������P1889 Doorbar, John �������������������������������������������������P1244 Dorak, Mehmet T. �������������������������������������������P1627 Dorman, Jennie B. ��������������������������������������������P848 dos Santos, Alia ������������������������������������������������P946 Dou, Zhen �������������������������������������������������������P1908 Doudna, Jennifer A. �����������������������������P1180,P2394 Doudrick, Kyle ������������������������������������������������P1696 Douglas, Foster ����������������������������������������������P2144 Doupe, David P. ����������������������������������������������P2386 Dovala, Dustin ������������������������������������������������P1844 Dovas, Athanassios ���������������������������������������� P1102 Dowd, Georgina C. �����������������������������������������P2408

Dowdy, Steven F. ��������������������������������������������P1038 Dowell, Hannah ������������������������������������������������P681 Downey, Bryan ��������������������������������������� P333,P867 Downing, Griffin M. �������������������������������������������P494 Downing, Kenneth H. �������������������������������������P1787 Drain, Allison �������������������������������������������������� P1158 Dranka, Brian P. ��������������������������������������������������P57 Dray, Eloise ���������������������������������������������������� P1133 Drerup, Catherine ���������������������� P113,P1413,P2379 Drew, David ������������������������������������������������������P852 DrewesTartarotti, Tatiana ��������������������������������P1201 Dreyfuss, Juliana L. ����������������������������������������P2226 Driss, Adel ������������������������������������������������������P2163 Driver, Jonathan W. ������������������������������������������P130 Drizyte, Kristina ������������������������������������������������P435 Drubin, David G. P110,P389,P392,P411,P724,P932, ������������������������������������������������������������������������P1806 Drummond, Iain A. ������������������������������������������P1265 Drummond, Paul ������������������������������������������������P28 d’Santos, Clive �����������������������������������������������P1074 Du, Shengwang ���������������������������������� P1078,P1296 Du, Yiqin ���������������������������������������������������������P2456 Duan, Liting ��������������������������������������������������������P54 Duan, Suzann ��������������������������������������� P337,P1977 Duarte, Adriana D. ��������������������������������������������P658 Dubash, Adi D. ���������������P645,P2182,P2267,P2283 Dubey, Ramin ���������������������������������������������������P559 DuBois, Julian C. ��������������������������������������������P1922 Ducommun, Bernard ��������������������������������������P1971 Duda, Zachary ������������������������������������������������P2015 Duell, Erika �����������������������������������������������������P1482 Duennwald, Martin L. ���������������������������������������P706 Duff, Jennifer D. ������������������������������������������������P671 Duffey, Chris ���������������������������������������������������P1235 Duffner, Emily R. ���������������������������������������������P1229 Duffy, Heather �������������������������������������������������P2462 Duffy, Michael P. �����������������������������������������������P822 Dufresne, Julie �����������������������������������������������P1592 Duhart, Juan C. ����������������������������������������������P1576 Dulyaninova, Natalya G. ���������������������������������P2240 Dumas, Marc ����������������P1628,P2310,P2402,P2403 Dumas, Megan �������������������������������������������������P773 Dumasia, Kushaan D. ����������������������������������������P76 Dumbali, Sandeep ������������������������������������������P1461 Dumbre-Patil, Arti �������������������������������������������P1887 Dumenil, Guillaume ����������������������������������������P2412 Dumitru, AnaMaria G. ���������������������������������������P199 Dumont, Julien ���� P168, P175,P1069,P1902,P1904 Dumont, Maxime P. ������������������������������������������P865 Dumont, Sophie �P1021,P1161,P1894,P1896,P1911 Duncan, Mara C. ����������������������������������� P408, P423 Dunlap, Jay C. ��������������������������������������������������P362 Dunn, Alexander R. ����������������� P2225,P2254,P2396 Dunn, Teresa ��������������������������������������������������P1364 Dunn, William A. ���������������������������������������������P1255 Dunne, Padraig ����������������������������������������������P1660 Duong, Thuy-Linh ���������������������������������������������P479 Dupuy, Jean-William ���������������������������������������P1486 Duran, Camille ��������������������������������������������������P628 Duran, Charity ������������������������������������������������P2107 Duran, Lisset ��������������������������������������������������P1961 Durbec, Pascale ���������������������������������������������P2451 Durnaoglu, Serpen �������������������������������������������P742 Duronio, Bob ��������������������������������������������������P1232 Dutcher, Susan K. ����������������� P1001, P1002, P1670 Dutta, Dipannita ����������������������������������������������P1260 Dutta, Shubham ���������������������������������������������P1472 Dutta, Soumita �������������������������������������� P162,P1817 Duty, Khursana ��������������������������������������� P532,P534 Dwivedi, Bhakti ����������������������������������������������� P1143 Dwyer, Noelle D. �������������������������� P174, P177, P476 Dymek, Erin E. �������������������������������������������������P997

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Earnshaw, William C. ................P235,P1065,P1066, ..............................................................P1067,P1893 Eaton, Benjamin A. �����������������������������������������P1664 Ebbert, Patrick ������������������������������������� P138, P1808 Ebner, Michael ������������������������������������������������P1406 Ebrahim, Seham ���������������������������������������������P1452 Echard, Arnaud F. �������������������������������������������P1862 Echeverría, Olga M. �����������������������������������������P674 Eck, Elizabeth C. �������������������������������������������� P1185

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Eckart, Michael R. ������������������������������������������P2184 Eckert, Kristin A. ���������������������������������������������P1097 Ecklund, Kari ��������������������������������������������������P1772 Eddy, Robert J. �������������������������������������������������P601 Edelmaier, Christopher �����������������������������������P1020 Edens, Lisa J. ���������������������������������������������������P364 Edgerton, Heather ��������������������������������������������P196 Edwalds-Gilbert, Gretchen �����������������������������P2140 Edwards, Frances ������������������������������������������P1069 Edwards, Kei Auyndria �����������������������������������P1054 Edwards, Robert H. ����������������������������������������P1294 Edzuka, Tomoya ��������������������������������������������� P1811 Eftekharian, Shaya �����������������������������������������P1336 Eftimiades, Alex ����������������������������������������������P2292 Egan, MacKennon E. ���������������������������������������P800 Egbuta, Chinaza �����������������������������������������������P665 Egelston, Jennifer �������������������������������������������P1397 Eggert, Ulrike ��������������������������������������������������P1864 Ehrenfeld, Ingrid P. �����������������������������������������P1985 Eibes, Susana ��������������������������������������������������P970 Eichel, Kelsie ��������������������������������������������������P1686 Eilstein, Joan ��������������������������������������������������P2302 Einstein, Lily C������������������������������������ P2349, P2351 Eisenberg, Amy R. ������������������������������������������ P1195 Eisenhoffer, George T. ��������������������������������������P320 Eisenstat, David �����������������������������������������������P316 Ejikemeuwa, Amara ������������������������������������������P534 Ekiert, Damian C. ���������������������������������������������P802 Eklund, Lauri ��������������������������������������������������P2297 Elbaum-Garfinkle, Shana ���������������������������������P714 Eldredge, Luke �����������������������������������������������P2267 El-Gebali, Sara �����������������������������������������������P1541 Elgin, Sarah C. ���������������������������������������������������P27 Elia, Natalie ���������������������������������������� P1834,P1868 Elias, Carlos N. �������������������������������������������������P659 Elias, Dominique �������������������������������������������� P1153 Eliceiri, Kevin ���������������������������������������� P847,P1501 Elkabetz, Yechiel ��������������������������������������������P1071 Ellenberg, Jan �������������������������������������� P232,P1657 Ellington, Lacey ���������������������������������������������� P2119 Elliott, Andrew ���������������������������������������������������P984 Elliott, Hunter L. ������������������������������������������������P662 Elliott, Hunter D. ���������������������������������������������P1363 Ellis, Joseph A. �����������������������������������������������P2021 Elmore, Zachary C. ������������������������������������������P170 Elnatan, Dan ���������������������������������������������������P1869 Elosegui, Alberto ����������������������������������������������P650 Elowe, Sabine ������������������������������������������������P1909 Elshazzly, Mohamed E. ���������������������������������� P1193 Elting, Mary W. �����������������������������������������������P1021 Elul, Tamira M. ��������������������������������������������������P477 El Waly, Bilal ���������������������������������������������������P2451 Elwell, Cherilyn ������������������������������������P2410,P2411 Embong, A.Karim ������������������������������������������� P1100 Emery, Gregory ����������������������������������������������P1434 Emmerich, Veronica ���������������������������������������P1597 Emmett, Grace �������������������������������������������������P589 Emr, Scott D. ��������������������������������������������������P1256 Ems-McClung, Stephanie C. ����� P245,P1764,P1883 Endo, Toshiya �������������������������������������������������P1342 Engdahl, Ashton J. �����������������������������������������P2339 Engebrecht, JoAnne ���������������������������������������P1033 Engel, Benjamin D. �����������������������������������������P2091 Engel, Joanne N. ��������������������������������P2410, P2411 England, Jeneffer �������������������������������������������P2186 Engle, Staci E. ��������������������������������������������������P159 Engler, Adam J. ������������������������������������������������P664 Enns, Caroline A. ����������������������������������������������P574 Enomoto, Atsushi ���������������������������������������������P787 Entenberg, David ����������������������������������������������P341 Eo, MiYoung �����������������������������������������������������P856 Erb, Marcella L. ������������������������������������������������P800 Erbacher, Patrick ����������������������������������������������P865 Erdjument-Bromage, Hediye ����������������������������P288 Erdmann, Dominique ��������������������������������������P2302 Erdmann, Rainer ��������������������������������������������P1658 Erdogan, Begum �������������������������������������������� P1155 Erdogan, Burcu ����������������������������������������������P1808 Erices, José I. �������������������������������������������������P1985 Eriksson, John E. ���������������������������������������������P628 Erinc, Mustafa ������������������������������������������������P1921 Eringa, Etto �������������������������������������������������������P668 Ermolaeva, Svetlana ��������������������������������������P1596 Ernst, Peter ����������������������������������������������������P1280

Ero-Tolliver, Isi A. ����������������������������������������������P836 Ershov, Dmitry ������������������������������������������������P2098 Ervasti, James M. ������������������������������� P1715,P1798 Escobar, María L. ���������������������������������������������P674 Escribano, Jorge ����������������������������������������������P655 Eshun-Wilson, Lisa �����������������������������������������P1261 Eskin, Tania L. ������������������������������������������������P1253 Espana-Serrano, Laura ����������������������������������P1925 Espinosa, Horacio D. ��������������������������������������P1449 Espinosade Los Reyes, Santiago ��������������������P575 Espinoza, Felipe �����������������������������������������������P291 Esquivel, Mario �����������������������������������������������P2281 Estes, Brett �����������������������������������������������������P1881 Esteve, Aurore ��������������������������������������������������P875 Estrem, Cassi E. ���������������������������������������������P1775 Ethell, Iryna M. �����������������������������������������������P1504 Ettinger, Andreas W. ���������������������������������������P1799 Eum, Juneyong ����������������������������������������������P1547 Eunbi, Jo ����������������������������������������������� P280,P1111 Evans, Ashley J. ���������������������������������������������P1310 Evans, Edward L. �������������������������������������������P1634 Evans, Irene M. ���������������������������������������������� P1100 Evans, Matthew �������������������������������������� P137,P138 Eveno, Clarisse ���������������������������������������������� P1153 Ewald, Andrew J. ��������������������� P1137,P1167,P1475 Ewald, Makena L. ���������������������������������������������P609 Exner, Cameron ���������������������������������������������P1591 Ezquerra, Artur �������������������������������������������������P970 Ezratty, Ellen J. ����������������������������������������������� P2116 Ezzoukhry, Zakaria �����������������������������������������P1486

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Fabi, Francois ��������������������������������������P1119,P2212 Fabian, Lacramioara L. ������������������������������������P366 Fabig, Gunar ���������������������������������������� P255,P1888 Fachinetti, Daniele �������������������������������� P203,P1062 Fackler, Oliver T. �����������������������������������������������P106 Fadavi, Darya ���������������������������������������������������P602 Fadero, Tanner ���������������������������������������������������P47 Fadil, Sana �����������������������������������������������������P2087 Fadness, Sela R. ����������������������������������������������P222 Fadul, John �������������������������������������������������������P320 Fagerstrom, Carey J. �������������������������� P1070,P1573 Fahrenkrog, Birthe ��������������������������������������������P371 Fahy, Kenneth ������������������������������������������������P1660 Faix, Jan �������������������������������������������������������������P85 Fajloun, Ziad ���������������������������������������������������P1044 Falk, Samantha J. ������������������������������������������P1063 Fall, Jenny ������������������������������������� P507,P508,P623 Falleiros-Junior, Luiz Roberto �������������������������P1565 Fan, Ching-Hsiang �������������������������������������������P716 Fan, Chunyan �������������������������������������������������P2131 Fan, Lucy X. �����������������������������������������������������P157 Fan, Shih-Jung �������������������������������������������������P339 Fan, Yiping �����������������������������������������������������P1963 Fang, Chieh-Ting ��������������������������������������������P1082 Fang, Jia-You �������������������������������������������������P1926 Fang, Jie ��������������������������������������������������������� P1174 Fanniel, Victor ���������������������������������������������������P290 Farache, Dorian ������������������������������������������������P968 Farajallah Hosseini, Zeinab ������������������������������P761 Farber, Steven A. ������������������������������������ P56,P1352 Farese, Robert V. �������������������������������������������P2149 Farhadifar, Reza ����������������������������������� P776,P1888 Farhan, Hesso ������������������������������������������������P1528 Farias, Jorge G. ������������������������������������������������P684 Farinade Souza, Marcos ��������������������������������P2287 Farino, Zachary J. ����������������������������������������������P30 Farkhondeh, Atena ������������������������������������������� P112 Farley, Madeline M. ������������������������������������������P544 Farmer, Andrew ������������������������������������������������P871 Farreira, Davis ������������������������������������������������P1597 Farrell, Kristen B. ����������������������������������������������P384 Farrell, Martilias S. ������������������������������������������P1264 Fassler, Jan S. ������������������������������������������������P1557 Fässler, Reinhard �����������������������������������������������P98 Faulds, Kelsie J. ���������������������������������������������P1397 Faundez, Victor ���������������������������������� P1289,P2135 Faust, James J. ����������������������������������������������P1696 Fazeem, Mohamed ����������������������������������������P1607 Fazio, Elena N. �������������������������������������������������P706 Fealey, Michael E. ��������������������������������������������P473 Fedorova, Natalia V. ���������������������������������������P1488

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Fedyna, Vira ���������������������������������������������������P2322 Fees, Colby P. ��������������������������������������������������P131 Fegaras, Eleni ��������������������������������������������������P219 Fekonja, Nina ������������������������������������������������� P1138 Fekri, Farnaz ��������������������������������������������������P1085 Feldman, Jessica L. ������������������������������� P986,P991 Feliciano, Daniel ���������������������������������������������P2143 Feliciano-Ildefonso, Jeremy J. ������������������������P1923 Feliz-Mosquea, Yismeilin R. ��������������� P1974,P1975 Felt, Kristen D. ��������������������������������������������������P220 Feltri, MariaLaura �������������������������������������������P2172 Feng, Chengye �������������������������������������������������P977 Feng, Di ����������������������������������������������������������P1009 Feng, Qingzhou ������������������������������������������������ P118 Feng, Siyu ������������������������������������������������������P1677 Feng, Xin-Hua ��������������������������������������������������P692 Feng, Xu �����������������������������������������������������������P639 Feng, Yu ���������������������������������������������������������P1578 Feng, Yuehan ���������������������������������������������������P710 Feng, Zhi ����������������������������������������������������������P413 Fenger, Joelle M. ��������������������������������������������P1967 Fenix, Aidan �������������������������������� P925, P954,P1859 Fennell, Anne �����������������������������������������������������P60 Fenster, Steven D. �������������������������������� P483,P2038 Fenyo, David �������������������������������������������������� P1184 Ferguson, Kayla L. �����������������������������������������P1517 Ferguson, Shawn M. ������������������� P10,P1282,P1283 Feric, Marina ����������������������������������������������������P714 Feringa, Femke M. �����������������������������������������P1040 Fernandes, Ricardo ������������������������������ P596,P2193 Fernandez, Christian ��������������������������������������P2307 Fernandez, Jorge H. ���������������������������������������P1929 Fernandez, Josiah ������������������������������������������P1958 Fernandez-Busnadiego, Ruben �����������������������P400 Fernández-Capetillo, Oscar ���������������������������P1051 Fernandez-Gonzalez, Rodrigo �������������������������P768 Ferrada, Luciano ����������������������������������������������P672 Ferraro, Teresa �����������������������������������������������P1550 Ferras, Cristina �����������������������������������������������P1060 Ferreira, Luísa ��������������������������������������������������P218 Ferreira, Mariana L. ����������������������������������������P2226 Fessenden, Tim ����������������������������������������������P2246 Feth, Brian ��������������������������������������������������������P867 Fetter, Richard ��������������������������������������� P485, P486 Fey, Dirk �����������������������������������������������������������P717 ffrench-Constant, Charles �������������������������������P2222 Fidler, Aaron L. ��������������������������������������� P26,P1499 Field, Christine M. ��������������������������������������������P169 Field, Seth J. ��������������������������������������������������P1863 Figard, Lauren R. ���������������������������������������������P902 Figueira, Ana C. ���������������������������������������������� P1188 Figueroa, Elías �������������������������������������������������P684 Figueroa, Jaime E. ����������������������������������������� P1181 Figueroa, Kayla-Marie ������������������������������������P1588 Figueroa, Ricardo A. �����������������������������������������P381 Fili, Natalia ���������������������������������������������� P946,P966 Filiakova, Nadezhda A. �����������������������������������P2381 Filippov-Levi, Natalie ����������������������������������������P338 Filter, Joshua J. ������������������������������������������������P466 Fina, Marie �����������������������������������������������������P1387 Finby, Brooks S. ���������������������������������������������������P8 Finch, Lila ���������������������������������������������������������P830 Findley-VanNostrand, Danielle �������������������������P838 Fink, Kyle D. �����������������������������������������������������P884 Fink, Lynn ������������������������������������������������������� P1133 Fink, Sarah �������������������������������������������������������P194 Finke, Eliza A. ���������������������������������������������������P351 Finkelstein, David �������������������������������������������P1963 Finseth, Lisbet T. ��������������������������������������������P2378 Firat-Karalar, Elif N. ����������������������������������������P1823 Firtel, Richard A. ���������������������������������������������P1489 Fischer, Robert S. ������������������������ P917,P952,P2117 Fischer, Wolfgang �������������������������������������������P1482 Fischer-Friedrich, Elisabeth ������������������������������P713 Fischer-Stenger, Krista ��������������������������� P570,P575 Fiscus, Alexandria ������������������������������������������P1013 Fisher, Cole ����������������������������������������������������P1623 Fisher, Peter �����������������������������������������������������P420 Fisher, Robin S. ����������������������������������������������P1270 FitzGerald, Garret A. ��������������������������������������P1545 Fitzgerald, Ivy ���������������������������������������������������P422 Fitzpatrick, Vincent �����������������������������������������P2289 Flamion, Bruno �����������������������������������������������P1267 Flavell, Richard A. ������������������������������������������P1742

 121

AUTHOR INDEX Fletcher, Daniel A. ������������������������� P248,P588,P617 Flibotte, Stephane ��������������������������������������������P746 Fliesler, Steven J. ��������������������������������������������� P511 Floor, Stephen N. �������������������������������������������P2394 Floren, Muskan ����������������������������������������������� P1171 Florens, Laurence �������������������������������� P707,P1081 FloresAbuna, Rodrigo P. �����������������������������������P889 Flynn, Lauren E. ���������������������������������������������P2272 Flyvbjerg, Henrik ����������������������������������������������P961 Focia, Pamela J. �����������������������������������������������P517 Fogerson, Stephanie M. ���������������������� P779, P2368 Fogle, Homer ��������������������������������������������������P1544 Foley, Kristie K. ���������������������������������������������������P16 Folker, Eric S. �������������������P363,P372,P1718,P2465 Folkmann, Andrew W. ��������������������������������������P470 Follain, Gautier ����������������������������������������������� P1138 Follenzi, Antonia ���������������������������������������������P1414 Fomicheva, Maria ���������������������������������������������P457 Foncy, Julie �������������������������������������������������������P875 Fong, ChiiShyang �������������������������������������������P1027 Fonseca, Cindy ����������������������������������������������P1901 Foolad, Negar �������������������������������������������������P1633 Foreman, Oded ������������������������������������������������P999 Forer, Arthur �����������������������������������������������������P219 Forero, Juan P. �������������������������������������������������P363 Forero, Maria E. ����������������������������������� P406,P1621 Forgione, Pat ��������������������������������������������������P1086 Fornes, Miguel W. ��������������������������������������������P552 Forren, Bronsen N. �����������������������������������������P2405 Forsburg, Susan L. �����������������������������������������P1043 Forster, Mercedes S. ��������������������������������������P1530 Forston, Michael D. ����������������������������������������P2318 Forteza, Radia ��������������������������������������������������P456 Forti, Fabio L. �������������������������������������������������P2176 Fortwendel, Jarrod R. �������������������������������������P1723 Foss, Jacqueline I. �������������������������������������������P306 Foster, Leigh A. ����������������������������������������������P1687 Foster, Leonard J. ������������������������������������������P2244 Foster, Olivia ����������������������������������������������������P440 Foster, Peter J. �������������������������� P245, P973, P1016 Fostok, Sabreen F. �������������������������������������������P631 Fotouhi, Maryam ����������������������������������������������P439 Fotovati, Abbas ������������������������������������P1151,P2113 Founounou, Nabila �������������������������������������������P776 Fourel, Laure ��������������������������������������������������P2289 Fourkas, John T. ��������������������������������������������� P2117 Fourriere, Lou �������������������������������������������������P1287 Fox, Melissa M. ������������������������������������������������P317 Fraile-Ramos, Alberto ���������������������������������������P407 Fraley, Stephanie I. ����������������������������������������� P1139 Frame, Fiona M. ���������������������������������������������P1098 Franchi, Jocelyne �������������������������������������������P2443 Francis, Heather L. ������������������������������� P344,P1651 Francis, Sabah M. ��������������������������������������������P279 Francis, Sharon C. �����������������������������������������P2163 Franck, Christian ��������������������������������������������P2225 Francl, Andrew �������������������������������������������������P137 Franco, Omar E. ��������������������������������������������� P1155 Francois, Paul ������������������������������������������������P1023 François, Joshua J. ����������������������������������������P1489 Frand, Alison R. ������������������������������������������������P920 Frangou, Costa ������������������������ P1173,P2440,P2458 Frank, Joachim ���������������������������������������������������P30 Franke, Werner W. �����������������������������������������P2269 Frantz, Christian ��������������������������������������������� P1161 Franz, Clemens M. �����������������������������������������P2232 Franzmann, Titus �������������������������������������������� P1184 Frappart, Lucien ��������������������������������������������� P2113 Fraser, Scott E. ���������������������������������������������������P68 Frassato, Austyn �������������������������������������������������P70 Fratti, Rutilio ���������������������������������������������������P1278 Frech, Fabio ���������������������������������������������������P2469 Frederick, Danielle �����������������������������������������P1608 Freedman, Simon ���������������������������������������������P919 Freeman, Amanda ������������������������������������������P2135 Freeman, Taylor ����������������������������������������������P1940 Frei, Erich �������������������������������������������������������P2364 Freikamp, Andrea �������������������������������������������P1068 Freise, Anika �������������������������������������������������������P85 Freisinger, Christina ���������������������������������������P1501 Freiss, Stefanie ������������������������������������������������P207 Freitag, Angelika �����������������������������������������������P947 Freitag, Johannes ���������������������������������������������P516 Freitas, Gileade P. ������������������������� P814,P817,P889

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Freitas, Vanessa M. ������������������P1149,P1164,P1165 FreitasFilho, Edismauro G. �������������������������������P585 Freixo, Francisco ����������������������������������������������P975 Frémont, Stéphane �����������������������������������������P1862 French, Bradley T. ������������������������������������������P1061 French, Samuel W. �����������������������������������������P1606 Frenz, Lucas �����������������������������������������������������P890 Freund, Guillaume ��������������������������������������������P865 Frey, Daniel ������������������������������������������������������P139 Freyberg, Zachary ����������������������������������������������P30 Freymann, Douglas M. �������������������������������������P517 Fricke, Stephanie L. ���������������������������������������P1634 Fridell, Yih-Woei ���������������������������������������������P1305 Fridman, Karen �������������������������������������������������P370 Fried, Susan ���������������������������������������������������P1375 Friedland, Julie ����������������������������������������������� P1161 Friedman, Alan �����������������������������������������������P2103 Friedman, Joel M. �������������������������������������������P1802 Froemming, Gabriele R. ���������������������������������P1962 Fröhlich, Florian ���������������������������������������������� P1511 Frolova, Liliya �������������������������������������������������P1928 Fromherz, Sylvia ������������������������������������������������P70 Fromme, J. C. ����������������������������������������� P418,P444 Fronek, Lisa ����������������������������������������������������P1200 Frosi, Yuri ���������������������������������������������������������P233 Frost, Adam �������������������������������������������� P496,P498 Fruhmann, Gernot ��������������������������������������������P371 Fu, Afu ������������������������������������������������������������ P1110 Fu, Chuanhai �������������������������������������� P1792,P1908 Fu, Dong ���������������������������������������������������������P2105 Fu, Kai ������������������������������������������������������������P2392 Fu, Meng-meng ����������������������������������������������P2379 Fu, Xiao ����������������������������������������������������������P1653 Fuchs, Christiane �������������������������������������������P2371 Fuchs, Elaine ����������������������������������������������������P863 Fuchs, Margit ����������������������������������������������������P693 Fuentes, Ernesto ����������������������������������������������P465 Fuentes, Jaime J. ������������������������������� P1631,P1633 Fuhrmann, Sabine ��������������������������������������������P781 Fujii, Tomoaki ��������������������������������������������������P1559 Fujiki, Yukio ����������������������������������������������������P2152 Fujino, Tomofumi ����������������������������������������������P270 Fujinoki, Masakatsu ����������������������������������������P1014 Fujita, Ayano ����������������������������������������� P614,P2237 Fujita, Barbara M. ���������������������������������������������P951 Fujita, Eri ��������������������������������������������������������P2301 Fujita, Keisuke ������������������������������������������������P2008 Fujiwara, Keigi �������������������������������������� P869,P2198 Fujiwara, Sachiko ���������������������������������������������P610 Fujiwara, Yuusuke �������������������������������� P682,P1655 Fukamizo, Tamo ���������������������������������������������P1625 Fukuda, Mitsunori ���������������������������������������������P434 Fukuda, Wakao ����������������������������������������������P2004 Fuller, Gerald G. ���������������������������������������������P2254 Funaba, Masayuki ������������������������������������������P1642 Funabiki, Hironori ���������������������������������������������P223 Funes, Abi ��������������������������������������������������������P552 Fung, Karen ����������������������������������������������������P1845 Funk, Laura C. ������������������������������������������������P1057 Fürstenberg, Nicoline �������������������������������������P1839 Fürthauer, Sebastian ������������������� P240,P245,P1016 Furukawa, Yoichi ��������������������������������������������P1559 Furusawa, Kotaro ���������������������������������������������P434 Furuta, Masakazu ���������������������������������������������P725

G

G.Duijf, Pascal H. �������������������������������������������P1959 Gabelev, Liliya ��������������������������������������������������P523 Gabriel, Michelle ���������������������������������������������P2457 Gabriele, Sylvain ������������P734,P1738,P2260,P2290 Gabrielli, Brian G. �������������������������������������������P1959 Gabrilovich, Dmitry I. ����������������������������������������P708 Gache, Vincent �����������������������������������������������P2366 Gachet, Yannick �����������������������������������������������P242 Gadal, Olivier ��������������������������������������������������P2146 Gadila, Shiva Kumar Goud �����������������������������P1291 Gaertig, Jacek ���������������������������������������� P993,P995 Gage, Jacob ���������������������������������������������������P1700 Gagliardi, Paolo A. ��������������������������������������������P924 Gahl, William A. ����������������������������������������������P1281 Gaillard, Jeremie ����������������������������������������������P129 Gal, Ian M. ��������������������������������������������������������P648 Gal, Lihi ������������������������������������������������������������P408

Galan, Jacob ����������������������������������������������������P334 Galanti, Lior ����������������������������������������������������P1546 Galantino-Homer, Hannah ������������������������������P1507 Galazka, Jonathan M. ������������������������������������P1544 Galbier, Lucas ������������������������������������������������P2209 Galbraith, Catherine G. ������������������������������������P648 Galbraith, James A. ������������������������������������������P648 Galjart, Niels ���������������������������������������������������P1060 Galkin, Vitold E. ����������������������������������������������P1866 Galkina, Svetlana I. ����������������������������������������P1488 Galland, Rémi �����������������������������������������������������P36 Gallazzini, Morgan ������������������������������������������P2203 Galletta, Brian J. ���������������������������������������������P1070 Galli, Lisa M. ���������������������������������������������������P1372 Gallicano, G. I. ������������������������������������������������P2372 Gallo, Luciana ��������������������������������������������������P442 Gallo-Fox, Jennifer �����������������������������������������������P2 Gan, Jia H. �����������������������������������������������������P2415 Gandy, Lucas ��������������������������������������������������P1678 Ganem, Neil J. �������������������������������������P1109,P2197 Ganti, Ketaki ���������������������������������������������������P1244 Ganzinger, Kristina A. �������������������������������������P2193 Gao, Chun ��������������������������������������������������������P692 Gao, Guang ����������������������������������������������������P2162 Gao, Haishan �������������������������������������������������P1059 Gao, Jing ��������������������������������������������������������P2191 Gao, Junjie �����������������������������������������������������P2155 Gao, Nan �������������������������������������������������������� P1411 Gao, Qiang �����������������������������������������������������P2142 Gao, Shaorong ����������������������������������������������� P1199 Gao, Xiaohua �������������������������������������������������P1419 Gao, Yuchen �����������������������������������������������������P860 Gao, Zhaobing ������������������������������������������������P2131 Garachtchenko, Tatiana ������������������������������������P871 Garate, Fernanda �������������������������������������������P2339 Garbarino, Joan ���������������������������������������������� P1122 Garbe, James �������������������������������������������������P2229 Garcea, Robert L. �������������������������������������������P1604 Garcia, Ellen �����������������������������������������������������P190 Garcia, Enrique J. �������������������������������������������P2332 Garcia, Galo,III �����������������������������������������������P1004 Garcia, Hernan G. ������������ P792,P793,P1185,P1189 Garcia, K.Christopher C. ����������������������������������P596 Garcia, Miguel A. ��������������������������������������������P2224 Garcia, Noelle �������������������������������������������������P2402 Garcia-Aguirre, Ian A. �������������������������������������P2303 GarcíaAznar, José M. ���������������������������������������P655 Garcia-Barrio, Minerva T. ��������������������������������P2163 Garcia-Hernandez, Alejandra �������������������������P1477 García León, Daniel �����������������������������������������P637 Garcia-Mata, Rafael �������P465,P2173,P2174,P2245 Garcia-Parajo, Maria ����������������������������������������P416 Garcia-Pelagio, Karla P. �����������������������������������P624 Gardel, Margaret L. ................P92,P104,P611,P613, ...............................................................P919,P2246 Gardiner, Jaye C. �������������������������������������������P1602 Gardner, Adam �������������������������������������������������P320 Gardner, Melissa K. ������������P142,P196,P244,P1023 Gareil, Nelly ����������������������������������������������������P1287 Garner, Ethan C. ���������������P795, P798,P807,P1724 Garner, Rikki M. ������������������������������������������������P913 Garr, Casey L. ������������������������������������������������������P1 Garri, Carolina ��������������������������������������������������P285 Garrido, Wallys �����������������������������������������������P2185 Garten, Matthias ���������������������������������������������P1446 Gartner, Zev J. ������������������P323,P733,P2201,P2229 Garza, Kristine M. �������������������������������������������P2427 Gasek, Nathan �����������������������������������������������P2471 Gasparski, Alexander N. ���������������������������������P2235 Gassama, Ama �����������������������������������������������P1348 Gatla, Himavanth R. ���������������������� P266,P267,P273 Gatlin, Jesse C. ����������������������������������������������P1884 Gatti, Maurizio ��������������������������������������������������P204 Gau, David ������������������������������������������� P900,P1428 Gaudet, Rachelle ��������������������������������������������P1399 Gaudet, Suzanne ���������������������������������������������P558 Gautam, Jaya ����������������������������������������� P268,P274 Gauthereau, Isabel �����������������������������������������P2090 Gauthier, Nils C. ���������������������������������������������P1742 Gauthier-Rouviere, Cecile ������������������������������P1250 Gautreau, Alexis ������������������������������������� P75,P1979 Gavet, Olivier C. ���������������������������������������������P2190 Gavis, Elizabeth R. �������������������������������������������P213 Gawlas, Sonja ������������������������������������������������P2371

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Gayan, Sukanya ��������������������������������������������� P1140 Gayek, Anna S. ����������������������������������������������P1751 Gayrard, Charlene ������������������������������������������P1463 Gaytan, Norma L. ���������������������������������������������P513 Ge, Xijin ��������������������������������������������������������������P60 Geffers, Robert ���������������������������������������������������P93 Gehlhausen, Jeffry R. ���������������������������������������P217 Geisinger, Jonathan M. ����������������������������������P1039 Geissmann, Frederic ����������������������������������������P789 Gelfand, Vladimir I. �����������������������������������������P1760 Gemma, Carly A. �������������������������������� P1361,P2388 Genereaux, Julie ����������������������������������������������P698 Genest, Mallory ����������������������������������������������P1250 Genisson, Jean Luc ������������������������������������������P812 Gentile, Francesco �����������������������������������������P1537 Gentili, Matteo ��������������������������������������������������P376 Genuth, Miriam �����������������������������������������������P2354 George, Andrea ������������������������������������������������P782 George, Dale ��������������������������������������������������P2377 George, Nancy �����������������������������������������������P1541 Georgescu, Constantin �����������������������������������P2005 Georgess, Dan �����������������������������������������������P1475 Georgiadou, Maria ������������������������������������������P1439 Gerassimov, Nathalie �������������������������������������P2357 Gerbi, Susan A. ������������������������������������������������P201 Gereau, Robert W. �����������������������������������������P1583 Gergely, Fanni ������������������������������������������������P1074 Gergely, Zachary ��������������������������������������������P1020 Gerhold, Abigail R. �������������������������������������������P247 Gerke, Volker ��������������������������������������������������P2070 Gerlich, Daniel W. ���������������������� P226,P1990,P2094 Gerson, Adina �������������������������������������������������P1546 Gerson, Julia E. ����������������������������������������������P1531 Gerst, Jeffrey ��������������������������������������������������P1337 Gertler, Frank B. ��������������������������������������������� P1163 Gestwicki, Jason ����������������������������������������������P887 Gettings, Melanie �������������������������������������������P1455 Geyer, Elisabeth A. �������������������������������������������P130 Geyer, Matthias ��������������������������������������������������P85 Ghaemmaghami, Amir ������������������������������������P2234 Ghaffarizadeh, Ahmadreza �������������������������������P285 Ghanbari, Parisa ����������������������������������������������P257 Gharakhanian, Editte ��������������������������������������P2080 Gharibi, Armen �����������������������������������������������P1947 Ghavami, Ali ���������������������������������������������������P2033 Ghersi, Alexis �������������������������������������������������P1776 Ghiani, Cristina A. �������������������������������������������P1270 Ghosh, Alokendra ���������������������������������������������P438 Ghosh, Ananda �����������������������������������������������P1316 Ghosh, Dhiman ���������������������������������������������� P1115 Ghosh, Pradipta �����������������������������������������������P307 Ghosh, Richik N. ������������������������������������������������P42 Ghosh, Saikat ������������������������������������������������� P1115 Ghosh, Santanu K. ����������������������������������������� P1115 Giacomello, Marta ������������������������������������������P1325 Giagtzoglou, Nikolas ����������������������������������������P531 GiamXueLin, Maybelline ����������������������������������P241 Giannone, Gregory �����������������������������������������P2280 Giannouli, ChristinaI����������������������������������������P1364 Giashuddin, Shah ������������������������������� P1974,P1975 Gibeaux, Romain ��������������������������������������������P1448 Gibson, Matthew C. ���������������������������������������� P2119 Gierman, Emma C. �����������������������������������������P1618 Giger, Roman J. �����������������������������������������������P569 Giginis, Frantzeska �����������������������������������������P1701 Gilbert, Catherine E. �����������������������������������������P417 Gilbert, Donna � P1494,P1917,P1918,P1919, P1922 Gilbert, Mary ������������������������������������������� P302,P638 Gilbert, Rachel M. ���������������������������������������������P375 Gilbert-Ross, Melissa ����������������������������� P312,P313 Gilde, Flora �����������������������������������������������������P2289 Gil-krzewska, Aleksandra ���������������������������������P916 Gillette, Jennifer M. ��������������������� P586,P587,P1171 Gillies, Taryn E. �������������������������������������������������P560 Gillingham, Alison �������������������������������������������P2056 Gilmore, Khari ������������������������������������������������P1762 Gilmore, Samuel P. ��������������������������������� P570,P575 Gimpel, Petra ���������������������������������������������������P988 Gimzewski, James K. �������������������������������������P2392 Gingras, Anne-Claude ������������������������������������P1400 Giovannone, Adrian J. ��������������������������������������P407 Giovannucci, David R. ������������������������������������P2064 Giovinazzi, Serena �����������������������������������������P2006 Girard, Nicholas ����������������������������������������������P1318

Gireud, Monica B. ������������������������������� P1252,P1257 Girón Bravo, Marlene M. ��������������������������������P2063 Gist, Neferteri �������������������������������������������������P2449 Gitai, Zemer ������������������������������������������������������P803 Githaka, John M. ����������������������������������������������P593 Gitler, Aaron ����������������������������������������������������P2158 Gittzus, Jordan �������������������������������������������������P397 Giunta, Simona �������������������������������������������������P223 Gladden, Andrew B. �����������������������������������������P455 Gladfelter, Amy S. ����������P362,P1446, P1457,P1669 Glaser, Matthew A. �����������������������������������������P1020 Glaser, Shannon S. ������������������������������������������P344 Glass, Christopher K. �������������������������������������P1038 Gläßer, Christine ������������������������������������������������P98 Glazier, James A. �������������������������������������������P1653 Glick, Benjamin S. ��������������������������������������������P422 Glikbarg, Chloe ����������������������������������� P2324,P2333 Glinos, George D. ���������������������������������������������P578 Globus, Ruth K. ����������������������� P1953,P2324,P2333 Gloerich, Martijn ��������������������������������� P1466,P1467 Glotzer, Michael ������������������������������������������������ P611 Glukhova, Samantha ����������������������������������������P824 Gnann, Christian ��������������P508,P623,P1675,P1782 Gnazzo, Megan M. �������������������������������������������P173 Go, Dam ����������������������������������������������� P677,P2413 Goberahan, Deborah ����������������������������������������P339 Godbout, Roseline ��������������������������������������������P316 Godin, Matthew ����������������������������������������������P1363 Godinho, Susana A. ��������������������������� P1079,P1080 Godsel, Lisa M. ����������������������������������������������P1449 Goehring, Nathan W. ����������������������������������������P452 Goel, Aviva J. ��������������������������������������������������P2406 Goere, Diane �������������������������������������������������� P1153 Goessling, Wolfram ����������������������������������������P2137 Goetz, Jacky G. ���������������������������������������������� P1138 Goga, Andrei ��������������������������������������������������P1957 Gogendeau, Delphine ��������������������������������������P180 Goicoechea, Silvia M. �������������� P2173,P2174,P2245 Gokce, Ozgun ������������������������������������������������P1681 Gokden, Alper �������������������������������������������������P1058 Göke, Aylin �����������������������������������������������������P1334 Gokhale, Avanti ���������������������������������� P1289,P2135 Gold, Leslie I. ���������������������������������������������������P665 Gold, Michael R. �����������������������������������������������P933 Goldberg, Alfred L. �����������������������������������������P2478 Goldberg, Anna R. ������������������������������������������P1431 Goldberg, Michael L. ����������������������������������������P466 Golden, Judith P. ��������������������������������������������P1583 Goldfien, Andrea C. ������������������������������������������P848 Golding, Adriana E. ����������������������������������������P2178 Goldowitz, Daniel ������������������������������������������� P2113 Goldsmith, Brett R. �����������������������������������������P2334 Goldsmith, Jennifer ������������������������������������������P999 Goldsmith, Juliet ��������������������������������� P2077,P2319 Goldstein, Bob ����������������� P2, P66,P450,P696,P940 Goluguri, Rama R. ��������������������������������������������P701 Gomes, Edgar R. ����������������������������������������������P988 Gomes, Marcelo D. ����������������������������������������P1401 Gomes-Santos†, Carina S. ����������������������������P1287 Gomez, Veronica ��������������������������������������������P1324 Gómez, Claudio J. ������������������������������������������P1610 Gomez Cavazos, Juan S. �������������������������������P1855 Gomez-Lopez, Juan de Dios �� P2040,P2042, P2041 Gómez Monsiváis, Wendy L. ��������������������������P2023 Gomzikova, Marina ���������������������������������������� P1116 Gonczy, Pierre ��������������������������������������������������P139 Gong, Ai-Yu ����������������������������������������������������P2416 Gong, Delquin ������������������������������������������������P1431 Gong, Lili ��������������������������������������������������������P1380 Gonnermann, Carina ��������������������������������������P2232 Gonsalvez, Graydon B. ��������������������� P1453, P1759 Gonye, Anna ������������������������������������������� P570,P575 Gonzales, Stephanie C. ��������� P1494,P1917,P1918, ����������������������������������������������������������� P1919, P1922 Gonzalez, Alexis �����������������������������������������������P425 Gonzalez, Carlos B. �����������������������������������������P529 Gonzalez, Carolina �������������������������������������������P529 Gonzalez, Hugo ����������������������������������������������P1964 González, Alfonso ������������������������������������������P1262 González, Mauricio �������������������������������������������P291 Gonzalez-Billaul, Christian �������������������������������P434 Gonzalez-Gaitan, Marcos �������������������������������P1803 Gonzalez-Mariscal, Lorenza ���������������������������P2271

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

González-Morales, Nicanor ������������������������������P914 Gonzalez-Reyes, Christian ����������������������������� P1166 Gonzalez-Silva, Natalio E. ������������������������������P1230 Gonzalez-Vargas, Carlos I. �����������������������������P1521 Good, Matthew C.  P737, P738, P739,P2349,P2351 Goode, Bruce L. ��������� P86,P90,P140,P1729, P904, ���������������������������������������������������������������P911,P2472 Goodkov, Andrew �������������������������������������������P1596 Goodman, Joel M. ������������������������������������������P2142 Goodman, Joshua ������������������������������������������P1027 Goodman, Lindsey D. ���������������������������������������P348 Goodman, Miriam B. ����������������������������������������P486 Goodnight, Davis W. ���������������������������������������P1877 Goodson, Holly V. ���������������������� P731,P1704,P1812 Goodwin, Katharine E. �������������������������������������P649 Gopal, Pallavi P. ���������������������������������������������P1307 Gopalakrishnan, Vidya �����������������������������������P1945 Göpfert, Martin C. ����������������������������������� P618,P964 Gopinathan, Ajay ����������������������������������������������P123 Gorbsky, Gary J������������������������������������ .P230,P1019 Gordon, Ana ���������������������������������������������������P1685 Gordon, Donna M. ������������������������������������������P2171 Gordon, Patricia B. �����������������������������������������P1298 Gordon, Sharona E. �������������������������������������������P49 Gorjanacz, Matyas �����������������������������������������P1033 Görlich, Dirk ���������������������������������������� P1666,P2031 Gormley, Claire �����������������������������������������������P1516 Gorur, Amita �����������������������������������������������������P429 Goshia, Tyler �������������������������������������������������� P1139 Goshima, Gohta ������������������������ P135,P1758,P1811 Goss, John W. ������������������������������������������������P1847 Gosselin, Natalie J. ����������������������������������������P2194 Goto, Kaoru ������������������������������������������ P566,P1636 Goto, Motoharu ����������������������������������������������P1981 Goto, Tatsufumi ����������������������������������������������P2181 Gotting, Kirsten �����������������������������������������������P2389 Gottschamel, Teresa ���������������������������������������P2371 Gottschling, Daniel E. ������������������������ P1298, P1351 Götz, Lou ��������������������������������������������������������P1541 Gou, Xuewen ��������������������������������������������������P2391 Goud, Bruno ������� P500,P1287,P1288,P1447,P1756 Goudot, Christel ���������������������������������������������P2219 Gould, Kathleen L. �� P170,P212,P908,P1843,P1848 Goupil, Eugénie ������������������������������������������������P176 Gourdie, Robert ������������������������������������������������P632 Gousset, Karine ������������������������������������ P960,P1685 Govind, Shubha ����������������������������������������������P2422 Gowrishankar, Swetha �����������������������������������P1282 Goyal, Ruchi ��������������������������������������������������� P1170 Goyal, Yogesh ������������������������������������������������P1555 Grabowski, Catalina P. �����������������������������������P1262 Graef, Ralph �����������������������������������������������������P216 Graichen, Mary E. ��������������������������������������������P271 Grainger, Tabatha ����������������������������������������������� P11 Grandy, Elizabeth �������������������������������������������P2166 Granger, Katelynn M. �������������������������������������P1899 Grant, Barth ������������������������������������������������������P436 Grashoff, Carsten �������������������������������������������P1068 Grass, Carina ������������������������������������������������� P1154 Grattan, Rachel ����������������������������������������������P1418 Gratton, Jean-Philippe ������������������������������������P2255 Graves, Dianna ������������������������������������������������P852 Gray, Elizabeth C. �������������������������������������������P2069 Gray, Kelsey M. ����������������������������������������������P1525 Gray, Peter �����������������������������������������������������P1482 Gray, Ryan ������������������������������������������������������P2379 Graziano, Brian R. ��������������������� P732,P1431,P2252 Green, Ardawna J. ������������������������������������������P1543 Green, Kathleen J. ������������������ P1449,P2283,P2356 Green, Marc D. �����������������������������������������������P1043 Green, Rebecca A. ������������������ P1546,P1855,P1863 Greenan, Garrett ����������������������������������������������P802 Greenberg, Charles ������������������������������������������P972 Greenberg, Roger A. ���������������������������P1141,P1228 Greene, Casey S. �������������������������������������������P1545 Greenlee, Matt ������������������������������������������������P1788 Gregg, Morgan �����������������������������������������������P1391 Gregory, Mary �������������������������������������������������P1592 Greiner, Doug ���������������������������������������������������P890 Grenci, Gianluca �������������������������������������������������P36 Grenfell, Andrew W. ������������������������������ P197,P1015 Grenier, Kathy ������������������������������������������������P2212 Griebenow, Kai H. �������������������������������P1113,P1943 Griffin, Erik ������������������������������������������������������ P2111

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AUTHOR INDEX Griffin, Gerald D. ����������������������������������������������P810 Grigoriev, Ilya ���������������������������������������� P139,P1078 Grill, Stephan W. � P452,P700,P1550,P2068, P2365 Grillo-Bosch, Dolors ���������������������������������������P2090 Grillo-Hill, Bree �����������������������������������������������P2281 Grima, Jonathan ���������������������������������������������P2035 Grimes, Martha M. ������������������������������������������P1632 Grimm, Casey C. ��������������������������������������������P1379 Grimmer, Peter �����������������������������������������������P2225 Grisar, Thierry �������������������������������������������������P2343 Grishin, Nick V. �����������������������������������������������P2414 Gristock, Rachel A. �������������������������������������������P289 Gröbe, Lothar �����������������������������������������������������P93 Groebner, Jennifer L. ��������������������������������������P2063 Grogan, Depresia �������������������������������������������P1542 Groisman, Alex �����������������������������������������������P2227 Gros, Robert ���������������������������������������������������P2272 Grosheva, Inna ���������������������������������������������������P94 Gross, Peter �����������������������������������������������������P452 Gross, Steven P. ���������������������������������������������P1753 Grosse, Robert ��������������������������������������� P106,P319 Grosser, Ondine ���������������������������������������������P2342 Grosser, Tilo ���������������������������������������������������P1545 Großhans, Jörg ������������������������������������������������P964 Grossniklaus, Hans E. ��������������������������������������P313 Grove, Anne ���������������������������������������������������P2007 Groves, Jay T. ������� P389,P598,P1157,P1398,P2093 Gruber, Achim �������������������������������������������������P2253 Gruber, Christina �������������������������������������������� P1168 Grunert, Christiane �������������������������������������������P484 Grünewald, Kay ����������������������������������������������P2097 Grunwald, David ���������������������������������������������P1989 Grzesiuk, Elzbieta ������������������������������������������P1954 Gu, Chad ��������������������������������������������������������P2037 Gu, Changdai ������������������������������������� P1435,P1436 Gu, Frank �������������������������������������������������������P1690 Gu, Guoqiang ��������������������������������������� P502,P1809 Gu, Mingyu ��������������������������������������������� P496,P498 Gu, Ying ���������������������������������� P1745,P1853, P1952 Gu, Yusu ���������������������������������������������������������P2266 Guan, Chonglin ������������������������������������������������P618 Guarnaccia, Corrado �������������������������������������� P1126 Guarner-Lans, Verónica ���������������������������������P2482 Gubbels, Marc-Jan �����������������������������������������P2069 Guere, Christelle ��������������������������������������������P1354 Guerin-Peyrou, Geraldine ��������������������������������P865 Guérois, Raphaël �������������������������������������������P1979 Guerra, Flávia D. ��������������������������������������������P1505 Guerrero, Jesus ����������������������������������������������P1576 Guerrier, Sabrice ��������������������������������������������P2086 Guertin, David ������������������������������������������������P1375 Guha, Mayukh ���������������������������������������� P993,P995 Guha, Prasun �������������������������������������������������P2327 Guignet, Michelle ����������������������������������������������P976 Guild, Joshua �������������������������������������������������P1896 Guillaud, Laurent ��������������������������������������������P1308 Guillen, Rodrigo X. �������������������������������������������P212 Guillou, Lionel �������������������������������������������������P2220 Guiney, Evan L. ����������������������������������������������P1256 Guiraud, Alexandre �����������������������������������������P2366 Guizzunti, Gianni ��������������������������������������������P1880 Gulvady, Anushree C. �������������������������������������P1485 Gunawardane, Ruwanthi �������������������������� P59,P861 Gundersen, Gregg G. �������������������� P374,P462,P493 Gunning, Peter W. ����������������������� P905,P906,P1976 Gunsalus, Kearney T. ���������������������������������������P828 Gunsalus, Kris ������������������������������������������������P1546 Guo, Chin-Lin �����������������������������������������������������P40 Guo, Fengli �������������������������������������������������������P365 Guo, Haotian �������������������������������������������������� P2115 Guo, Li ������������������������������������������������������������P1213 Guo, Shunling �����������������������������������������������������P54 Guo, Siyang ����������������������������������������� P904, P1729 Guo, Wei ������������������������������������������������P438,P1161 Guo, Yanlin ����������������������������������������� P2382,P2384 Guo, Yong-Mei ������������������������������������������������P2181 Guo, Yu �����������������������������������������������������������P1625 Guo, Yusong ��������������������������������������� P1285,P1296 Guo, Zhenhuan ������������������������������������������������P953 Gupta, Mohan �������������������������������������������������P1885 Gupta, Nidhi �����������������������������������������������������P999 Gupta, Pratyush ���������������������������������������������P1527 Gupta, Sita �����������������������������������������������������P1364 Gupta, Vandana ����������������������������������������������P2137

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Gupton, John T. �������������������������������������� P570,P575 Gupton, Stephanie L. ������P480,P1264,P2054, P892 Gurchenkov, Basile ����������������������������������������� P1154 Gurel, Pinar S. ��������������������������������������� P917, P957 Gurug, Chandan ���������������������������������������������P2382 Gurung, Chandan �������������������������������������������P2384 Gurung, Pallavi �������������������������������������������������P567 Gurung, Sonam ����������������������������������������������P1310 Guse, Annika ��������������������������������������������������P1624 Gustafson, Margaret A. ������������������������������������P418 Guthrie, Christine ������������������������������������������� P1179 Gutierrez, Edgar ���������������������������������������������P2227 Gutierrez, Francisco �����������������������������������������P291 Gutiérrez, Ignacio ������������������������������������������� P1184 Gutiérrez, Nicolás ���������������������������������������������P291 Gutierrez-Iglesias, Gisela �������������������������������P2452 Gutiérrez-Iglesias, NellyDaniela ���������������������P2452 Guttman, Julian A. ������������������������������ P1721,P1722 Guttridge, Denis C. �����������������������������������������P1967 Guvakova, Marina A. ������������������������������������������P97 Guvener, Tuzun ����������������������������������������������P2421 Guzman, Camilo �����������������������������������������������P647 Guzman, Solimar P. ����������������������������������������P1943 Gygi, Steven P. �����������������������������������������������P1251 Gyoergy, Attila ������������������������������������������������P1438

H

Ha, JungMin �����������������������������������������������������P556 Ha, Kevin D. ���������������������������������������������������P1293 Ha, Kwon-Soo ������������������������������������������������P2340 Ha, Taekjip ������������������������������������������������������P1462 Haage, Amanda M. �������������������������������������������P649 Haas, Karen ���������������������������������������������������P1236 Haas, Vanessa ���������������������������������������������������P85 Haass, Nikolas K. �������������������������������������������P1959 Haataja, Mikko P. ��������������������������������������������P1697 Habelitz, Stefan ����������������������������������������������P2120 Haber, James E. ���������������������������������������������P2014 Habiyaremye, Julius ���������������������������������������P1849 Hackbarth, Mary E. �����������������������������������������P1281 Hackstadt, Ted ������������������������������������������������P2410 Hadjitheodorou, Amalia ����������������������������������P1239 Hadzic, Ermin �������������������������������������������������P1719 Haefner, Julia �������������������������������������������������P1074 Haering, Christian H. ����������������������������������������P233 Hafner, Antonina ��������������������������������������������� P1175 Hagendorff, Petra �����������������������������������������������P93 Hahn, Klaus M. ������������������������������������� P719,P1799 Hahn, Ute �������������������������������������������������������P1665 Haile, Olivia ����������������������������������������������������P1272 Haisler, William �����������������������������������������������P1700 Haka, Abigail S. ������������������������������������������������P579 Hake, Kayley H. ������������������������������������������������P777 Hakonarson, Hakon ������������������������������������������P827 Halavatyi, Aliaksandr ��������������������������������������P1719 Halfen, Jessica ���������������������������������������������������P93 Halfmann, Randal ���������������������������� P43,P699,P705 Hall, Alan ����������������������������������������������������������P324 Hall, Allison E. ������������������������������������������������P2278 Hall, David H. ���������������������������������������������������P992 Hall, Eric T. �������������������������������������������������������P557 Hall, Sallie L. �������������������������������������������������� P1187 Hallberg, Einar ��������������������������������������������������P381 Hallberg, Zachary F. �����������������������������������������P806 Hallett, Ryan A. �����������������������������������������������P1800 Halliday, Akacia K. ������������������������������������������ P1611 Halme, Adrian �������������������������������������������������P1568 Hamada, Keisuke �������������������������������������������P2463 Hamao, Kozue ��������������������������������������������������P143 Hamarneh, Ghassan ��������������������������������������P1661 Hambleton, Elizabeth A. ���������������������������������P1624 Hammad, Osama �������������������������������������������P1660 Hammer, John A. ��P80,P87,P481,P950,P955,P958, �������������������������������������������������������������� P1712,P959 Hammer, Susanne C. ���������������������������������������P260 Hammich, Hussein �����������������������������������������P1862 Hammock, Kendra ���������������������������������� P532,P534 Hammond, Ming C. ������������������������������������������P806 Hammonds-Odie, Latanya P. ���������������������P11,P829 Hamza, Alaaeldin A. ���������������������������������������P1927 Hamza, Nafisa ������������������������������������������������P2437 Han, Anthony �������������������������������������������������� P1139 Han, Bingjie ���������������������������������������������������� P2111

Han, Dasol ������������������������������������������������������P1567 Han, Dong-Wook ��������������������������������������������P2335 Han, Fang ���������������������������������� P667,P1584,P2400 Han, In-Seob ��������������������������������������������������P1807 Han, Jiye ��������������������������������������������������������P2335 Han, Kyoung-Youn ������������������ P2430,P2431,P2432 Han, Sangyoon J. �������������������������������������������P1243 Han, Simon �����������������������������������������������������P1887 Han, Siyang ������������������������������������������������������P607 Han, Tony ���������������������������������������������������������P439 Han, Xianghua ������������������������������������������������P2479 Hanafiah, Aflah ����������������������������������������������� P1100 Hanania, Yasmien ������������������������������������������P1504 Hanawa-Suetsugu, Kyoko ������������������������������P2138 Hanby, Hayley A. ��������������������������������������������P1276 Hancock, John F. ����������������������������������������������P541 Hancock, Kendall ���������������������������������������������P632 Hancock, William O. ���������������� ...P118,P127,P1761, .......................................................... .....P120,P1751 Hand, Marissa A. ��������������������������������������������P2066 Handigund, Mallikarjun ���������������������� P1561, P1649 Handoko, Lusy �����������������������������������������������P2008 Haney, Brian ���������������������������������������������������������P6 Hanigan, Marie H. ������������������������������������������P2439 Hanlin, Carey ��������������������������������������������������P2054 Hannibal, Roberta ��������������������������������������������P987 Hanover, John A. �������������������������������� P1369,P2010 Hansen, Scott D. ��������������������������������������������P1398 Hansma, Helen G. ��������������������������������������������P515 Hanson, Pamela K. ������������������������������������������P546 Hanzawa, Hiroko ����������������������������������������������P876 Hao, Yi-Heng ����������������������������������������������������P292 Hao, Yuxin ������������������������������������������������������P2186 Hara, Yusuke ��������������������������������������������������P1471 Harashima, Nozomi ������������������������������������������P656 Hardeman, Edna C. �������������������������������� P905,P906 Hardin, William �������������������������������������������������P934 Harding, Molly ������������������������������������������������P1413 Harding, Paul A. ��������������������������������� P1361,P2388 Haren, Laurence �����������������������������������������������P968 Hargrove, Laura ���������������������������������������������P1651 Hari-Gupta, Yukti ������������������������������������ P946,P966 Harkany, Tibor ������������������������������������������������P1785 Harker, Alyssa J. ��������������������������������������� P84,P891 Harland, Luke �������������������������������������������������P1940 Harland, Richard M. ���������������������������������������P1591 Harlepp, Sébastien ����������������������������������������� P1138 Harlin, Heather M. ��������������������������������������������P599 Harmon, Robert M. ��������������������������������� P92,P2356 Harn, HansI-Chen ��������������������������������������������P616 Harp, Marie �������������������������������������������������������P440 Harper, J. W. ������������������������������ P538,P1251,P2330 Harper, Logan ���������������������������������������������������P440 Harris, Adrian L. ������������������������������������������������P339 Harris, Kennedy ������������������������������������������������P810 Harris, Leigh K. �������������������������������������������������P794 Harris, Michael J. ������������������������������������������������P71 Harris-Arnold, Aleishia ������������������������������������P2420 Harrison, Morgan ��������������������������������������������P2127 Hart, Daniel ����������������������������������������������������P1589 Hart, Kevin C. ������������������������������������� P1466,P1467 Hart, Madeleine L. ������������������������������������������P1524 Hart, Ryan G. ���������������������������������������������������P385 Hartling, Rebecca G. ����������������������������������������P234 Hartnett, Andrej ������������������������������������������������P890 Hartwig, Cortnie ����������������������������������������������P2135 Harty, Breanne L. ������������������� P1317,P1583, P2379 Hartzell, Catherine A. �������������������������������������P1747 Hartzell, Harrison C. ���������������������������������������P2474 Harvey, Joseph D. ������������������������������������������P1386 Harvey, Kirsten �����������������������������������������������P2139 Haschke, Heiko ����������������������������������������������P2232 Hasdemir, Burcu ���������������������������������������������P1420 Hasebe, Yukio ������������������������������������������������P2301 Hasegawa, Shin ���������������������������������������������P1778 Hashimoto, Mitsuru ����������������������������������������P1339 Hashizume, Yoshio �����������������������������������������P1383 Haslam, Aidan ������������������������������������������������P2043 Hassinger, Julian E. ������������������������������������������P724 Hasson, Reed �������������������������������������������������P2144 Hata, Saori �������������������������������������������P116, P1304 Hata, Shoji ������������������������������������������������ P98,P210 Hatch, Ellen W. �����������������������������������������������P1418 Hattersley, Neil �����������������������������������������������P1902

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Hau, KwanTang ����������������������������������������������P1078 Hauck, Amy ����������������������������������������������������P1524 Haugsten, Ellen M. �������������������������������������������P404 Haugwitz, Michael ��������������������������������������������P871 Haupt, Armin ����������������������������������������� P445,P2098 Hauser, Cindy D. ������������������������������������������������P16 Hausrat, Torben ����������������������������������������������P1785 Hauswirth, Anna ��������������������������������������������� P2311 Hautaniemi, Sampsa ����������������������������������������P315 Havard, Jonathan ���������������������������������������������P865 Havel, Lauren S. �����������������������������������������������P313 Hawthorne, Jenci L. ��������������������������������������������P46 Hay, Ronald T. ������������������������������������������������P1532 Hayakawa, Makio ���������������������������������������������P270 Hayashi, Kanehiro ������������������������������������������P2344 Hayashi, Kumiko ��������������������������������������������P1778 Hayashi, Masahito ��������������������������������������������P722 Hayashi, Vanessa �������������������������������������������P1375 Hayashi, Yoshio ���������������������������������� P2463,P2466 Haydari, Zainab ����������������������������������������������P2228 Hayden, Katherine L. ����������������������������������������P845 Hayek, Summer R. �����������������������������������������P1632 Hayer, Arnold ��������������������������������������������������P1429 Hayes, James B. ��������������������������������������������P2417 Hayes, Michael �����������������������������������������������P1557 Hayrapetian, Laurie ������������������������������������������P141 Hays, Thomas S. ������������������������� P125,P473,P1299 Hayward, Simon W. ���������������������������������������� P1155 He, Miao ���������������������������������������������������������P1281 He, Shizhi ���������������������������������������������������������P324 He, Shuangba ��������������������������������������������������P324 He, Xia ������������������������������������������������������������ P1199 He, Ying ������������������������������������������������������������P217 He, Yuan ��������������������������������������������������������� P1174 He, Yudou ���������������������������������������������������������P989 He, Zhengcheng ��������������������������������������������� P2113 Heald, Rebecca ����������������P197,P248,P1015,P1017 Hearing, Patrick ����������������������������������������������P1622 Heasley, Lydia R. ��������������������������������������������P1895 Heath, Carissa M. �������������������������������������������P1870 Heavner, Mary E. ��������������������������������������������P2422 Hebert, Michael D. ��������������������������������������������P361 Hedeen, Danielle ����������������������������������������������P320 Heggeness, Misty L. �����������������������������������������P828 Hegsted, Anna ����������������������������������������������������P99 Heher, Philipp �������������������������������������������������P2371 Hehnly, Heidi ����������������������������� P592,P1548,P1859 Heier, Jonathon A. ������������������������������������������P1481 Heighington, Cassandra S. ����������������������������P1024 Heiligenstein, Xavier �����������������������������������������P499 Heim, Gudrun ���������������������������������������������������P521 Heiman, Maxwell G. ���������������������������������������P1473 Heiman-Patterson, Terry D. ����������������������������P1320 Heimsath, Ernest G. �������������������������������������������P83 Heimsath,Jr., Ernest G. ������������������������������������P950 Heisler, David B. �������������������������������������������������P78 Hejab, Nisreen M. �������������������������������������������P1787 Held, Paul G. ������������������������������������������ P57,P1088 Helenius, Ari ���������������������������������������������������P2097 Helfman, David M. ��������P1091,P1424,P1708,P1976 Helgeson, Luke A. ������������������������������������������P1912 Heliot, Laurent ������������������������������������ P1480,P2190 Hell, Johannes W. �������������������������������P1311,P2125 Hell, Stefan W. ������������������������������������������������P1657 Heller, Bradley A. ��������������������������������������������P1294 Helmke, Kara ��������������������������������������������������P1015 Helton, James ����������������������������������������������������P65 Hemachandra, Madhubhani �����������������������������P341 Hemalatha, Anupama �������������������������������������P1569 Hemmat, Mahya ��������������������������������� P1805,P2233 Hendel, Nathan L. ������������������������������������������ P1011 Henderson, Carl A. �����������������������������������������P2078 Henderson, Kiersten A. ����������������������������������P1298 Henderson, Paul T. �������������������������������������������P277 Henderson, Peter B. ��������������������������������������� P1311 Hengartner, Christoph J. ��������������������������������P1054 Hengst, Ulrich �������������������������������������������������P1323 Henkel, Arne �����������������������������������������������������P947 Henley, Jeremy M. ������������������������������������������P1310 Henley, Sheryce ���������������������������������������������P2434 Hennen, Jared ��������������������������������������������������P377 Hennessy, Laura E. ����������������������������������������P1320 Henty-Ridilla, Jessica L. �����������������������������������P140 Heo, Jin-Chul ��������������������������������������������������P2433

Heo, Jin-Mi �����������������������������������������������������P2330 Heo, Sukyeong �����������������������������������������������P1407 Heppert, Jennifer K. �������������������������������������������P66 Herbert, Alex ���������������������������������������������������P1998 Herbert, Amy L. ���������������������� P1317, P1583,P2379 Hercyk, Brian S. ���������������������������������������������P1867 Hergarden, Anne ��������������������������������������������P2125 Hermann, Greg J. ���������������������������������������������P440 Hermes, Doris ���������������������������������������������������P633 Hermes, Túlio A. ��������������������������������� P2468,P2470 Hermo, Louis ���������������������������������������� P501,P1592 Hermsmeier, Maiko ����������������������������������������P2435 Hernandez, Danielle �����������������������������������������P467 Hernandez, Javier �������������������������������������������P342 Hernandez, Octavio ����������������������������������������P1440 Hernandez, Rafael E. ���������������������������������������P326 Hernandez, Raquel ����������������������������������������P1597 Hernandez, Veronica L. ������������������������������������P681 Herrera, Antonio �����������������������������������������������P784 Herrera, Jeremy �����������������������������������������������P820 Herrmann, Harald �������������������������������������������P1717 Hersen, Pascal �������������������������������������������������P953 Hershberg, Uri ����������������������������������������������������P48 Hess, Harold F. �����������������������������������������������P2139 Hettema, Ewald H. �������������������������������������������P870 Hetz, Claudio ����������������������������������������������������P580 Hetzer, Martin W. �������������������������������� P1207,P1218 Heusèle, Catherine �����������������������������������������P1628 Heusinkveld, Lauren E. ����������������������������������P2417 Hicks, Derrick ���������������������������������������������������P803 Hicks, Lawrence J. �����������������������������������������P1453 Hickson, Gilles R. �������������������������������������������P1866 Hidai, Chiaki ����������������������������������������� P682,P1655 Higashi, Tomohito ��������������������� P635,P2270, P2367 Higashi, Tsunehito ��������������������������������������������P680 Higgins, Christopher D. ��������������������������������������P66 Higgins, Michael �����������������������������������������������P158 Higgs, Henry N. ������������������������������� P83,P89,P1343 Higuchi-Sanabria, Ryo �����������������������������������P1749 Hikosaka, Miku �������������������������������������������������P826 Hill, Malcolm S. �������������������������������������������������P948 Hille, Bertil �������������������������������������������� P555,P1410 Hilliker, Angie K. �����������P1200,P1201,P1202,P1203 Hilsenstein, Volker ����������������������������������������������P34 Hilton, Denise ��������������������������������������������������� P911 Himelstein, Daniel S. ��������������������������������������P1545 Hinchcliffe, Edward H. ��������������������������������������P222 Hines, Crystal �������������������������������������������������P1608 Hines, Justin K. ��������������������P695,P702,P703,P704 Hinton, Ayana M. ����������������������������������������������P308 Hinz, Boris ��������������������������������������������������������P652 Hipolito, Kevin J. ���������������������������������������������P1722 Hiraoka, Chinami ��������������������������������������������P1322 Hirata, Masato ������������������������������������ P1590,P2191 Hirokawa, Nobutaka �������������������� P112,P114,P1750 Hirotsu, Yoshifumi �������������������������������������������P2304 Hirsch, Sophia ��������������������������������������������������P168 Hirschberg, Koret ���������������������������������������������P415 Hirschmann, Jesse �������������������������������������������P290 Hirst, Linda �������������������������������������������������������P121 Hisaki, Yoshihiro ���������������������������������������������P1559 Hisanaga, Shin-ichi ������������������������������������������P434 Hissa, Barbara ����������������������������������������������������P92 Hitchcock, Olivia N. ����������������������������������������P1270 Hitoshi, Suzuki ������������������������������������������������P2450 Hivroz, Claire �������������������������������������� P2219,P2220 Hiwatashi, Yuji ������������������������������������������������P1889 Hjelmare, Martin ����� .P507,P508,P623,P859,P1675, .........................................................................P1782 Ho, Derek S. ���������������������������������������������������P2285 Ho, Kung-Hsien ����������������������������������������������P1809 Hoban, Kyle ������������������������������������������������������P393 Hochman-Mendez, Camila �����������������������������P2293 Hockemeyer, Dirk ��������������������������������� P392,P2394 Hocking Murray, Davina ���������������������������������P2078 Hocky, Glen M. ��������������������������������������� P100,P907 Hodges, Cameron ������������������������������������������P1226 Hodges, Kurt B. ������������������������������������������������P334 Hodzic, Didier ���������������������������������������������������P368 Hoege, Carsten ������������������������������������������������P452 Hoehne, Martin �����������������������������������������������P1005 Hoek, Tim A. �������������������������������������������������������P61 Hoesing, Elizabeth �������������������������������������������P557 Hoevenaars, Femke M. ������������������������������������P668

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Hoffman, Brenton D. ���������������������������������������P2123 Hoffman, Kristen ���������������������������������������������P1516 Hoffmann, Ingrid M. ������������������������������������������P207 Höfler, Rudolf ����������������������������������������������������P226 Hofmann, Wilma A. �������������������������������������������P340 Hofstetter, Katrina ���������������������������������������������P781 Hoft, Richard H. ����������������������������������������������P2314 Hohenbery, Travis ������������������������������������������� P1112 Holan, Vladimir �������������������������������������������������P819 Holaska, James M. �����������������������������������������P2021 Holdener, Bernadette C. ���������������������������������P1825 Holehouse, Alex S. �������������������������������������������P714 Holland, Andrew J. ������������������������������� P208,P1037 Hollerer, Ina ���������������������������������������������������� P1195 Hollingsworth, Natalie ���������������������������������������P206 Holowka, David A. ������������������������������������������P1409 Holst, Manuel ���������������������������������������������������P319 Holt, Liam J. ��������������������������������������������������� P1184 Holtstrom, Michael ����������������������������������������������P33 Holtzer, Laurent ����������������������������������������������P1803 Holtzman, Michael J. ��������������������������������������P1825 Holzbaur, Erika L. �������������������� P1300,P1307,P2156 Holzenburg, Andreas ��������������������������������������P2153 Homa, Kaitlin E. �������������������������������������� P100,P895 Homer, Christina M. ���������������������������������������� P1179 Honda, Hiroyuki ����������������������������������������������P1725 Hone, James ��������������������������������������������������P2141 Hong, Eun-Hye �������������������������������������������������P474 Hong, Hannah ��������������������������������������������������P408 Hong, Hee-do ���������������������������������������������������P549 Hong, Hyunsook �����������������������������������������������P823 Hong, Jinsung ����������������������������������������������������P87 Hong, Julie �������������������������������������������������������P283 Hong, Katrina �������������������������������������������������P1595 Hong, Seong Wook ������������������������������������������P825 Hong, Soo Jung ���������������������������������������������� P1105 Hong, Soonjin ������������������������������������ P1367, P1680 Hong, Sung-Eun ���������������������������������� P295, P1937 Hong, SunHae ��������������������������������������������������P392 Honjo, Yasuko ��������������������������������������������������P510 Honnert, Ulrike �������������������������������������������������P947 Honts, Jerry E. ������������������������������������������������P1013 Hoogendoorn, Sascha ��������������������������������������P164 Hoover, Malachia ����������������������� P283,P1482,P1947 Hope, Thomas J. ������������������������������������������������P30 Hoppe, Adam D. �� P60,P1263,P2444,P2445, P2067 Hoppe, George �����������������������������������������������P1648 Hoppins, Suzanne C. ���������������������������������������P518 Hoque Apu, Ehsanul ���������������������������������������P2297 Horan, Brandon G. �����������������������������������������P1726 Hordijk, Peter L. ������������������������������������ P668,P1454 Hori, Haruna ���������������������������������������������������P2291 Horii, Cassandra V. �������������������������������������������P830 Horinouchi, Takahiro �����������������������������������������P680 Horinouchi, Wataru �����������������������������������������P1638 Horita, Henrick ������������������������������������ P1367,P1680 Horne, Mary C. �������������������������� P293,P1311,P2125 Horowitz, Mark ��������������������������������������������������P485 Horwitz, Alan R. ����������������������������������������������P2123 Hoshi, Masato ��������������������������������������������������P155 Hoskins, Aaron A. ��������������������������������������������� P111 Hossain, M J. ����������������������������������������������������P232 Hosseinzadeh, Owen ���������������������������������������P780 Hotz, Manuel ��������������������������������������������������P2108 Hou, Titus ���������������������������������������������������������P465 Hou, Yue �����������������������������������������������������������P312 Houdusse, Anne M. ����������������������������������������P1862 Hough, Loren ��������������������������������������������������P1020 Housden, Benjamin E. ��������������������������������������P885 Housman, Max �����������������������������������������������P1441 Howard, Jason �����������������������������������������������P1660 Howard, Russell M. ����������������������������������������P2318 Howell, Brian W. ���������������������������������������������P2197 Howell, Shannon ����������������������������������������������P285 Howes, Stuart �������������������������������������������������P1787 Hozumi, Kentaro ��������������������������������� P2291,P2336 Hsieh, Wan-Ying �����������������������������������������������P288 Hsieh, Yi-Jui �����������������������������������������������������P689 Hsu, Jessica ���������������������������������������������������P1351 Hsu, Tzu-Han ���������������������������������������������������P548 Hsu, Yen-Pang �������������������������������������������������P798 Hsueh, Ying-chang ����������������������������������������� P1178 Htet, Zaw ��������������������������������������������������������P1765 Htwe, Susu �����������������������������������������������������P2234

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AUTHOR INDEX Hu, Boyi ������������������������������������������������������������P183 Hu, Changkun ������������������������������������������������ P1183 Hu, Chih-Chi A. ��������������������������������������� P275,P708 Hu, Jennifer L. ������������������������������������������������P2229 Hu, Jiandu ������������������������������������������������������P1915 Hu, Jiayue ������������������������������������������������������P1620 Hu, Ke �������������������������������������������������� P989,P1081 Hu, Longhua ���������������������������������������������������P1539 Hu, Ruikun ��������������������������������������������������������P151 Hu, Ruiying �������������������������������������������������������P502 Hu, Shiqiong �����������������������������������������������������P953 Hu, Xiao ����������������������������������������������������������P1701 Hu, XiaoPing ����������������������������������������������������P947 Hu, Yanhui ��������������������������������������������������������P885 Hu, Yizhou ��������������������������������������������������������P315 Hu, Yucheng �����������������������������������������������������P766 Hua, Shasha ���������������������������������������������������P2358 Huang, Anna ������������������������������������������� P252,P256 Huang, Bo ��������������������������������� P990,P1004,P1677 Huang, Changjin ���������������������������������������������P1449 Huang, Chi-Chou ������������������������������������ P872,P873 Huang, Chiu-Hui ���������������������������������������������P2159 Huang, Chun f. �����������������������������������������������P1791 Huang, EvaYi-Hsuan �������������������������� P2254,P2396 Huang, Fei ������������������������������������������������������P1474 Huang, Guozhong ������������������������������ P1598,P2169 Huang, Hai �������������������������������������������������������P938 Huang, Hector ������������������������������������ P2077,P2319 Huang, Jau-Shyang ������������������������������������������P565 Huang, Junqi �������������������������������������� P1745,P1853 Huang, Kerwyn C. ������������������������������������������P2217 Huang, Kun ����������������������������������������������������P2276 Huang, Lu ������������������������������������������� P1263,P2067 Huang, Ning �����������������������������������������������������P969 Huang, Pei-Hsin ������������������������������������� P512,P687 Huang, Roya E. ����������������������������������������������P2161 Huang, Shan ��������������������������������������������������P1009 Huang, Shengping ������������������������������������������P1835 Huang, Shi-Rong ��������������������������������������������P1000 Huang, Wei �������������������������������������������������������P441 Huang, Wei-En ������������������������������������� P716,P1000 Huang, Wei-Pang �������������������������������������������P2072 Huang, Weiyan �������������������������������������������������P820 Huang, Wendong ��������������������������������������������P1952 Huang, William Y. C. ����������������������������� P598,P1398 Huang, Xinming ������������������������������������������������P728 Huang, Yan ���������������������������������������� P1285, P1296 Huang, Yao-Shen ���������������������������������������������P716 Huang, Yixin ���������������������������������������������������P1654 Huang, Yongjun ������������������������������������������������P786 Huang, Yushuan ���������������������������������������������P2435 Hubbi, Maimon ����������������������������������������������� P1170 Huber, Otmar ��������������������������������������������������P2271 Hubmayr, Rolf D. ����������������������������������������������P820 Hübner, Angela �������������������������������������������������P412 Huckaba, Thomas M. �������������������������������������P1762 Hudson, Billy G. �������������������������������������� P26,P1499 Hudson, John W. ���������������������������������� P303,P2194 Hudson, Julie ������������������������������������������ P26,P1499 Huesca-Gómez, Claudia ��������������������������������P2482 Hueschen, Christina L. �����������������������������������P1894 Huggenberger, Reto ���������������������������������������P2310 Hughes, Ethan ������������������������������������������������P2350 Hughes, Jasmine H. ���������������������������������������P1951 Hughes, Michael W. �����������������������������������������P616 Hughes, Thom E. ��������������������������������������������P2208 Huh, YangHoon ����������������������������������������������P2133 Huh, YunHyun ������������������������������������������������ P1159 Huisman, Maximiliaan ������������������������������������P1989 Hull, Elizabeth E. �������������������������������� P1920,P2263 Hummer, Blake �����������������������������������������������P1294 Humphries, Ashley C. ������������������������������������� P2112 Humphries, Martin J. ���������������������������������� P72,P73 Humphry, Nicola ���������������������������������������������P2320 Hune, Samantha �������������������������������������������� P1187 Hung, Claudia ���������������������������������������������������P880 Hunter, Chris ��������������������������������������������������P2462 Hunter, Emily L. ���������������������������������� P1002,P1012 Hunter, Miranda V. ��������������������������������������������P768 Hu, Jim �����������������������������������������������������������P1542 Huq, Farah �������������������������������������������������������P465 Hur, GangMin ������������������������������������� P1093,P2205 Hur, Seong K. �������������������������������������������������P2374 Hurbain, Ilse �����������������������������������������������������P499

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Hurley, Edward �����������������������������������������������P2172 Hurley, James H. �������������������������������� P2093,P2316 Hurst, Logan ���������������������������������������������������P1278 Hurtado, Joanna ��������������������������������������������� P1120 Husain, Kabir ��������������������������������������������������P2201 Hussain, Saman �����������������������������������������������P795 Hussain, Syed ������������������������������������������������P1917 Hussein, Alaa ������������������������������������������������� P2110 Hussey, Michael R. �����������������������������������������P2465 Husson, Julien ������������������������������������������������P2220 Hüttenhain, Ruth ��������������������������������������������P1686 Huttenlocher, Anna �����������������������������������������P1501 Hutter, Heinz ���������������������������������������������������P2279 Hüttner, Clemens �������������������������������������������� P1168 Huynh, Brandon �����������������������������������������������P495 Huynh, Minh �������������������������������������������������������P31 Huynh, Walter �������������������������������������������������P1781 Huyot, Vincent ������������������������������������������������P2187 Hwang, ByungJoon J. �������������������������� P855,P1547 Hwang, Hyeon-Jeong ������������������������������������� P2211 Hwang, Jesse ���������������������������������������������������P572 Hwang, Joseph ������������������������������������ P858, P2183 Hwang, Juyeon ����������������������������������� P1002,P1012 Hwang, Sung-Hyun ������������������������������������������P335 Hwang, Sun-hee ���������������������������������������������P1828 Hwang, Yongsung ������������������������������������������P2299 Hwang, Yu-Chen ����������������������������������������������P989 Hyatt, Dylan M. �����������������������������������������������P2066 Hyle, Judith �����������������������������������������������������P1963 Hyman, Anthony A. ������������������������ P700,P713,P967 Hyndman, Brandy D. �������������������������������������� P1121 Hyttinen, Jari ����������������������������������������������������P637 Hyun, Joanne ���������������������������������������������������P191

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Ibarra, Arkaitz �������������������������������������������������P1218 Ibarra, Veronica ��������������������������������������������������P63 Ibrahim, Amr ���������������������������������������������������P1626 Icha, Jaroslav ���������������������������������������������������P484 Ichida, Justin ������������������������������������������ P872,P873 Ide, Takahiro ���������������������������������������������������P1001 Iftode, Cristina ������������������������������������������������P1701 Iglesias, Pablo ��������������������������������������������������P962 Ihalainen, Teemu ����������������������������������������������P637 Ihsan, Rana ����������������������������������������������������P1516 Ii, Hiromi �����������������������������������������������������������P261 Iimori, Makoto �������������������������������������������������P1018 Iizuka, Yoshie ���������������������������������������������������P142 Ijavi, Mahdiye ���������������������������������������������������P713 Ikebe, Mitsuo ����������������������������������������������������P956 Ikeda, Kazuho ������������������������������������� P874, P1778 Ikegami, Amanda ��������������������������������������������P1931 Ikegami, Koji ���������������������������������������������������P1383 Ikenouchi, Junichi ���������������������������������������������P927 Im, A-Rang �����������������������������������������������������P2446 Imagawa, Masayoshi �������������������������� P1638,P1981 Imai, Kaoru �������������������������������������������������������P826 Imaizumi, Kazunori �����������������������������������������P1041 Imajo, Risa �������������������������������������������������������P510 Imanaka, Tadayuki ��������������������������������������������P725 Imbert, Isabelle �����������������������������������������������P2402 Inaba, Kazuo ��������������������������������������������������P1001 Inaba, Yasuko �������������������������������������������������P1713 Inagaki, Naoyuki ������������������������������������� P482,P928 Ing, Lauren A. ������������������������������������������������� P1134 Inman, David R. ���������������������������������������������� P1156 Innis, Wendy �����������������������������������������������������P290 Inoue, Seika ���������������������������������������������������P2344 Inoue, Shigeyuki ���������������������������������������������P1750 Inoue, Takanari ����������������������������������� P1000,P1819 Insall, Robert H. ������������������������� P105,P1147,P1979 Insinna, Christine ��������������������������������������������P1827 Insolera, Ryan ������������������������������������������������P1305 Inuwa, Rabiu F. ����������������������������������������������� P1148 Ioannou, Maria S. ���������������������������������������������P439 Ireton, Keith ����������������������������������������������������P2408 Irianto, Jerome �������������������������� P600,P1141,P1228 Isan, Hatice ������������������������������������������ P526,P1921 Isermann, Philipp ���������������������������������� P375,P1221 Ishihara, Seiichiro ������������������������������������������� P1156 Ishihara, Yuka ������������������������������������������������� P1107 Ishii, Hirokazu ������������������������������������� P1669,P1810 Ishii, Maki �������������������������������������������������������P1699

Ishijima, Sanae A. �������������������������������������������P1625 Ishijima, Sumio �����������������������������������������������P1014 Ishikawa, Takashi ��������������������������������� P996,P1001 Ishikawa, Tomomi ���������������������������������������������P682 Ishov, Alexander M. ����������������������������������������P2006 Iskar, Murat �����������������������������������������������������P2092 Islek, Eylul ��������������������������������������������������������P432 Ismael, Amber ������������������������������������������������P1796 Ismail, Shehab ��������������������������������������������������P105 Ismail, Tayaba �������������������������������������������������P1563 Isoniemi, Kimmo �����������������������������������������������P628 Isseroff, Roslyn R. ������������������������������������������P1631 Itakura, Eisuke ������������������������������������ P2312,P2313 Ito, Hiromu ������������������������������������������������������P1934 Ito, Nanako �����������������������������������������������������P1725 Ito, Shuichi ������������������������������������������������������P1671 Itoh, Kohji ������������������������������������������������������� P1196 Itoh, Shuichi ����������������������������������������������������P1716 Itoh, Yuzuru ����������������������������������������������������P2138 Ivankovic, Mario ���������������������������������������������P2371 Ivanov, Andrei I. ���������������������������������������������� P1150 Ivanovska, Irena L. �����������������������������������������P1228 Ivaska, Johanna ����������������P402,P1439, P647,P650 Iwase, Shohei ���������������������������������������������������P901 Iwata-Otsubo, Aiko �����������������������������������������P1063 Iwenofu, Obiajulu H. ���������������������������������������P1967 Iyengar, Ravi ��������������������������������������������������P2141 Izoré, Thierry ����������������������������������������������������P795 Izquierdo, Denisse ������������������������������������������P1027

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J.A.Davies, Kelvin ������������������������������ P1512,P1523 Jabeen, Tayyaba ������������������������������������������������P82 Jack, Brittany ����������������������������������������������������P161 Jackson, Cynthia ����������������������������������������������P810 Jackson-Miller, Porshea ���������������������������������P1608 Jacob, Abitha ����������������������������������������������������P310 Jacob, Nitya P. ��������������������������������������������������P851 Jacob, Reeba S. ��������������������������������������������� P1115 Jacobs, Aaron T. �����������������������������������������������P289 Jacobs, Christopher R. ��������������������������� P149,P822 Jacobs, Damon T. �������������������������������������������P1832 jacquemet, guillaume ��������������������������������� P72,P73 Jacquet, Kevin ��������������������������������������������������P584 Jadot, Michel ��������������������������������������������������P1267 Jaeger, Jens ��������������������������������������������������� P1211 Jaffe, Gabriel ����������������������������������������������������P124 JafferAli, MohammedHakim �����������������������������P381 Jagga, Divya ��������������������������������������������������� P1123 Jagga, Divya ���������������������������������������������������P2076 Jahed, Zeinab �������������������P377,P602,P1690,P2288 Jahnel, Marcus ������������������������������������� P700,P2068 Jahroudi, Nadia ������������������������������������������������P316 Jaimovich, Ariel ����������������������������������������������P1049 Jain, Akanksha �����������������������������������������������P2365 Jain, Ankur ��������������������������������������������������������P726 Jain, Nimansha �������������������������������������������������P630 Jain, Sanjay ������������������������������������������������������P155 Jain, Sweta �����������������������������������������������������P1294 Jaiswal, Richa ������������������������������������������� P86, P90 Jakobs, Stefan ��������������������������������������������������P521 Jalal, Salma ������������������������������������������������������P918 Jalilian, Iman ��������������������������������������������������P1502 Jalink, Kees ����������������������������������������������������P1040 James, Allison A. ��������������������������������������������P1223 James, Andrea E. �������������������������������������������P1479 James, John R. ��������������������������������������������������P71 James, Noliyanda �������������������������������������������P1001 James, Paul F. ��������������������������������������������������P757 Jamur, Maria C. ������������������������������������������������P585 Jan, Lily Y. ������������������������������������������ P1319,P2121 Jan, Yuh N. ����������������������������������������� P1319,P2121 Jananji, Silvana ����������������������������������������������P1866 Janczarski, Stephane �������������������������������������P2366 Janes, Michael S. ���������������������������������������������P868 Janetopoulos, Chris J. ������������������������ P1441,P2087 Jang, Hee Yeon ����������������������������������������������P1436 Jang, Hyun-Jun ���������������������������������������������� P2211 Jang, Ik Soon ���������������������������������������� P280,P1111 Jang, Jong Seon ����������������������������������������������P556 Jang, Minsu ����������������������������������������������������P2071 Jang, Shyh-Ing �������������������������������������������������P576 Jang, Soo Hwa �����������������������������������������������P1807

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Jang, So Ri K. ������������������������������������������������P2136 Jang, SueIm ���������������������������������������������������P2286 Jani, Jitesh �����������������������������������������������������P2144 Jani, Maulik ����������������������������������������������������P2144 Jani, Vivek P. ��������������������������������������������������P1702 Janisch, Kerstin M. ��������������������������������� P174,P476 Janjanam, Jagadeesh ������������������������������������P2206 Janke, Carsten ������������������������������������� P249,P1785 Jankowska, Katarzyna I. ��������������������������������P1747 Janmey, Paul A. ������������������������������������������������P382 Jans, Daniel C. �������������������������������������������������P521 Jansen, Sebastian ������������������������������������������P1994 Jansen, Silvia ���������������������������������������������������P904 Jansova, Denisa ���������������������������������������������P1047 Janssen, Aniek �����������������������������������������������P2001 Janssen, Louise �����������������������������������������������P200 Jao, Dave �������������������������������������������������������P1701 Jaqaman, Khuloud ������������������������ P593,P597,P931 Jara, Nery ���������������������������������������������P514, P2114 Jaramillo, AnaMaria ����������������������������������������P2065 Jaramillo, Couger ���������������������������������������������P665 Jaramishian, Claire �����������������������������������������P1028 Jaron, Liu Z. ���������������������������������������������������P1214 Jasnin, Marion ��������������������������������������������������P939 Jasnow, David ������������������������������������������������P2037 Jaspan, Vita N. ���������������������������������� P1013, P1988 Jaspersen, Sue L. ������������������������������������������P1075 Jaszczak, Rebecca ����������������������������������������P1568 Jaulin, Fanny �������������������������������������������������� P1153 Jaumouillé, Valentin ������������������������������������������P103 Jaunky, Dilan ��������������������������������������������������P1086 Jauset, Cristina �����������������������������������������������P2002 Jaussi, Rolf �������������������������������������������������������P139 Javier, Leanne ��������������������������������������������������P890 Javorkova, Eliska ���������������������������������������������P819 Jawerth, Louise ������������������������������������������������P713 Jaworski, Jacek ������������������������������������������������P475 Jayant, Lalitha ������������������������������������������� P13, P15 Jayaraman, Swaathi �����������������������������������������P334 Jayaratne, Rashini ������������������������������������������P1616 Jayashankar, Vaishali �������������������������������������P1326 Jean, Daphney C. �������������������������������������������P1784 Jean, Grace H. �����������������������������������������������P1562 Jeannot, Pauline ���������������������������������������������P2239 Jeffery, Marquise A. ����������������������������������������P2263 Jenkins, Brian ���������������������������������������������������P621 Jensen, Eva B. �����������������������������������������������P1665 Jensen, Grant J. ������������������������������������� P30,P1851 Jensen, Helene H. �������������������������������� P642,P1665 Jensen, Jill B. ���������������������������������������������������P555 Jensen, Victor L. ����������������������������������� P152,P1840 Jeon, Hyeona �������������������������������������������������P2286 Jeon, Hye-Yoon ����������������������������������������������P2340 Jeon, NooLi ������������������������������������������������������P717 Jeon, Sejin ������������������������������������������������������P2347 Jeong, Byeong-Seon ����������������������������������������P274 Jeong, ChaeGyeong ��������������������������������������P1644 Jeong, Hyeon-Ju �������������������������������� P2370,P2467 Jeong, HyunSook �������������������������������������������P1435 Jeong, Jangho ������������������������������������������������ P1159 Jeong, Mi-Young �����������������������������������������������P533 Jeong, Myong-Ho ���������������������������������������������P771 Jeong, Seong Y. ���������������������������������������������P1094 Jeong, So-ra �����������������������������������������������������P549 Jeong, SukYeong �������������������������������������������P1976 Jeong, Woo-Jeong �������������������������������������������P278 Jeong, Youngeun ��������������������������������������������P1564 Jerde, Calvin R. ���������������������������������������������� P2011 Jeremic, Aleksandar M. ����������������������������������P1297 Jerman, Stephanie J. ���������������������������������������P156 Jerome, W. G. ������������������������������������������������P1499 Jeronimo-Monteiro, Valentin ���������������������������P1628 Jessen, Henning J. �����������������������������������������P1598 Jethwa, Devina M. ������������������������������������������P2250 Jevtic, Predrag �����������������������������������������������P1217 Jha, Ankita ������������������������������������������������������P1575 Jha, Narendra N. �������������������������������������������� P1115 Jha, Rupam ����������������������������������������������������P1779 Ji, Baohua ������������������������������������������������������P2298 Ji, Jiazheng ���������������������������������������������������� P1141 Ji, Wei �������������������������������������������������������������P2131 Ji, Weike ���������������������������������������������������������P1343 Ji, Wenbin �������������������������������������������������������P1026 Ji, Zhejian �������������������������������������������������������P1059

Jia, Luying ������������������������������������������������������P1059 Jia, Yue �����������������������������������������������������������P1078 Jiang, Jian ������������������������������������������������������P2171 Jiang, Jihong �������������������������������������������������� P2113 Jiang, Kai �������������������������������������������� P1078,P2358 Jiang, Kewu ������������������������������������������������������P766 Jiang, Ling ������������������������������������������������������P1212 Jiang, Nan ������������������������������������������������������P1664 Jiang, Qing ���������������������������������������� P1213, P2155 Jiang, Rui ���������������������������������������������������������P120 Jiang, Ting-Xin ��������������������������������������������������P760 Jiang, Yuwei �����������������������������������������������������P698 Jiang, Yuyang ���������������������������������������������������P995 Jimenez, Ana ����������������������������������������������������P376 Jimenez, Diana C. ������������������������������������������P1255 Jimenez, Erin A. �����������������������������������������������P837 Jimenez, Salma E. �������������������������������������������P342 Jimenez, Vanessa ��������������������������������������������P479 Jimenez-Garcia, Luis F. ����������������������������������P1234 Jiménez Gutiérrez, Elizabeth �������������������������P2041 Jimenez-Mallabrera, Cecilia �����������������������������P412 Jimenez-Sabinina, Vilma ��������������������������������P1657 Jin, Erli ��������������������������������������������������������������P707 Jin, HeeKyung ������������������������������������������������P2461 Jin, Hui ������������������������������������������������������������� P211 Jin, Hyeon-Ok ��������������������������������������� P295,P1937 Jin, Seok ���������������������������������������������������������P1436 Jin, SeoYeon ����������������������������������������������������P556 Jin, Shaobo ������������������������������������������������������P519 Jin, Taegun �������������������������������������������������������P477 Jin, Won J. ��������������������������������������������������������P331 Jin, Zhigang ������������������������������������������������������P272 Jiu, Yaming �����������������������������������������������������P1741 Jo, Areum �������������������������������������������������������P2467 Jo, Min-Guk ������������������������������������������������������P225 Jo, MyungHyun ����������������������������������������������P1462 Jo, Sung-Hee �������������������������������������������������P2413 Jo, Yu-Jin �������������������������������������������� P1739,P1740 Jobling, Michael G. �����������������������������������������P1357 Joel, Raingeaud ��������������������������������������������� P1153 Joffe, Aaron M. �������������������������������������������������P588 Joga, VenkataNeeha �����������������������������P811,P1950 Joglekar, Ajit P. ����������������������� P1887,P1913, P1907 Johansson, Hans E. ���������������������������������������P1673 Johansson, Marnie �������������������������������������������P196 John, Karin �������������������������������������������������������P129 Johnathan, Meaders �����������������������������������������P172 Johnson, Alyssa E. ����������������������������������������� P2311 Johnson, Charleen L������������������������� .P1317, P1583 Johnson, Colin P. ��������������������������������������������P2055 Johnson, Elizabeth L. ������������������������������������� P1190 Johnson, G.Allan ��������������������������������������������P1302 Johnson, Heath E. ������������������������������������������P1555 Johnson, Holly E. �������������������������������������������P1566 Johnson, Jeffrey ������������������������������������P152,P2411 Johnson, Margaret A. ���������������������������������������P839 Johnson, Matthew R. ��������������������������������������P1349 Johnson, Richard ����������������������� P971, P972,P1897 Johnson, Steve �����������������������������������������������P2379 Johnson, Whitney L. ���������������������������������������P2015 Johnson Sagolla, Meredith S. ����������������������������P63 Johnston, Adam ������������������������������������������������ P911 Johnston, Christopher A. ����������������������������������P246 Johnston, Danielle ��������������������� P430,P1940,P2272 Johri, Aanchal �����������������������������������������������������P19 Joiner, Aaron ����������������������������������������������������P444 Jokitalo, Eija ���������������������������������������������������P2268 Jonasson, Erin J. �������������������������������� P1704,P1812 Joncas, France-Hélène ���������������������������������� P1119 Jones, Celina Y. ������������������������������������������������P671 Jones, Christophe ������������������������������������������P2302 Jones, Gareth ���������������������������������������������������P844 Jones, Jennifer K. ���������������������������������������������P349 Jones, Keith T. ��������������������������������������������������P228 Jones, Kevin B. ������������������������������������������������P296 Jones, Michael �������������������������������������������������P873 Jones, Mikayla J. ����������������������������������������������P289 Jonikas, Martin �����������������������������������������������P2154 Jönsson, Peter �����������������������������������������������P2193 Jordan, Heather ����������������������������������������������P1768 Jordan, Jacqueline A. �����������������������������������������P22 Jorgensen, Erik ����������������������������������������������P2136 Jose, Antony M. ������������������������������������������������P350 Joshi, Bharat �������������������������������������� P2162,P2244

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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AUTHOR INDEX Kaneshiro, Jeanae M. ������������������������������������P1207 Kang, Byeong-Cheol ���������������������������� P754,P2296 Kang, Dongmin ������������������������� P583,P1407, P1408 Kang, Hojin �����������������������������������������������������P1491 Kang, In Soon ���������������������������������������� P563, P564 Kang, JeongHan �����������������������������������������������P467 Kang, Jong-Sun ������������������������� P771,P2370,P2467 Kang, Kidong �������������������������������������� P1093,P2205 Kang, Kwangil ������������������������������������������������P1938 Kang, Michael ���������������������������������������������������P571 Kang, Min-hee ������������������������������������������������P1514 Kang, Min-Kyung �������������������������������� P1478,P2455 Kang, Phillip H. �������������������������������������������������P571 Kang, Se-Hui ����������������������������������������� P280,P1111 Kang, Sun Woo Sophie ����������������������������������P2105 Kang, You Jung ����������������������������������������������P1751 Kang, Young-Hee ���������P1478,P2329,P2455,P2480 Kani, Kian ���������������������������������������������������������P285 Kanisicak, Onur ����������������������������������������������P1497 Kannan, Rekha ���������������������������������������������������P65 Kannan, Shravan ��������������������������������������������P1685 Kannon, Takayuki �������������������������������������������P2195 Kanoh, Hatsuho �������������������������������������� P641,P643 Kanter, Ellen ���������������������������������������������������P1323 Kapinos, Larisa E. ������������������������������������������P2037 Kapitein, Lukas C. ������������������������������������������P2358 Kaplan, Charlotte ����������������������������������������������P932 Kaplan, Kenneth B. ����������������������������������������P1028 Kaplunov, Jessica M. ��������������������������������������P1673 Kapoor, Tarun M. ��������������������������������������������P1787 Kapus, Andras ������������������������������������������������P2039 Kapustina, Maryna �������������������������������������������P903 Karagiannis, George S. ���������������������������������� P1136 Karagöz, Gulsun Elif ����������������������������P1510,P1511 Karahuseyinoglu, Sercin ��������������������������������P1553 Karamichos, Dimitrios ������������������������������������P1495 Karasmanis, Eva P. ����������������������������������������P1303 Karatekin, Erdem ��������������������������������������������P1854 Karginov, Andrei V. ����������������������������� P1491,P2187 Karlen, Karin L. �������������������������������������������������P587 Karpen, Gary H. �������������������������������� P1987, P2001 Karpova, Tatiana S. ����������������������������������������P1668 Karshafian, Raffi ���������������������������������������������P1085 Karunungan, Krystal �����������������������������������������P581 Käs, Josef �����������������������������������������������������������P85 Kasahara, Junya ����������������������������������������������P826 Kasai, Tomonari ����������������������������������������������P1946 Kashina, Anna S. ��������P1387,P2352, P1732, P1743 Kashino, Genro ����������������������������������������������P1089 Kasprowicz, Richard ���������������������������������������P1098 Kasri, Amal �����������������������������������������������������P1287 Kassianidou, Elena �����������������������������������������P2231 Kast, David J. �������������������������������������������������P1445 Kasymov, Vitaliy A. �����������������������������������������P2381 Katagiri, Fumihiko ������������������������������� P2291,P2336 Katerina, Suneel ���������������������������������������������P1831 Katkere, Bhuvana ������������������������������� P1640,P2418 Kato, Masato ����������������������������������������������������P625 Kato, Mayumi ������������������������������������������������� P1107 Kato, Yoshiki ��������������������������������������� P2180,P2473 Katoch, Parul ����������������������������������������������������P630 Katoh, Yohei ���������������������������������������������������P1833 Katrukha, Eugene ���������������������������������������������P139 Katsanis, Nicholas ��������������������������������������������P160 Katsikis, Georgios ����������������������������������������������P19 Katsuno, Hiroko ������������������������������������������������P928 Katz, David J. ���������������������������������������������������P834 Katz, Sophie S. �������������������������������������������������P920 Katzemich, Anja ����������������������������������������������P2361 Katzmann, David J. ����������������������������������������P2150 Kauanova, Sholpan �������������������� P133,P134, P1087 Kaufman, Gili ��������������������������������������������������P2292 Kaufman, Paul D. �������������������������������������������P1986 Kaulich, Manuel ����������������������������������������������P1038 Kaur, Charanjeet ��������������������������������������������P1057 Kaur, Harmeet ������������������������������������P1123, P2076 Kaur, Jaspreet ������������������������������������������������P1737 Kausel, Gudrun ���������������������������������������������� P1181 Kaushik, Gaurav �����������������������������������������������P664 Kaushik, Shelly ����������������������������������������������� P1160 Kaverina, Irina ��������������������P502,P978,P979,P1809 Kawamata, Shin �������������������������������������������������P45 Kawamoto, Sachiyo ���������������������������������������� P1193 Kawamura, Masaki �����������������������������������������P2304

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Kawana, Masataka �������������������������������������������P942 Kawano, Kenji ������������������������������������������������P1089 Kawata, Junko ������������������������������������������������P2304 Kawata, Yasunobu ������������������������������������������P2304 Kawauchi, Akihiro ���������������������������������������������P261 Kaya, Abdullah �����������������������������������������������P2012 Kaya, Ozlem T. �������������������������������������������������P526 Kaye, Bryan T. ��������������������������������������������������P973 Kayed, Rakez �������������������������������������������������P1531 Kaze, Mo ����������������������������������������������� P37, P1612 Kazemzadeh-Atoufi, Maryam ������������������������� P1185 KC, Birendra ���������������������������������������������������P2027 Ke, Hongmei �����������������������������������������������������P413 Keating, Brendan J. ������������������������������������������P827 Keck, James �����������������������������������������������������P277 Kee, Anthony J. ������������������������������������������������P906 Kee, Yun ���������������������������������������������� P855, P1547 Keeley, Daniel P. �����������������������������������������������P653 Keeley, Tyler �����������������������������������������������������P893 Keely, Patricia J. ��������������������������������������������� P1156 Kefalov, Vladimir �����������������������������������������������P368 Keifenheim, Daniel �������������������������������������������P196 Keil, Sarah ������������������������������������������������������P1434 Kelber, Jonathan A. ������������������� P283,P1482,P1947 Kelland, Chelsea ��������������������������������������������P1762 Kelleher, Dermot �����������������������������������������������P886 Keller, Lani C. �������������������������������������������������P1318 Keller, Sarah L. �������������������������������������������������P540 Kelley, Charlotte F. ��������������������������������������������P941 Kelley, Charlotte A. �����������������������������������������P1394 Kelliher, Michael T. �������������������������������������������� P111 Kellogg, Elizabeth H. ��������������������������������������P1787 Kellogg, Mariko �������������������������������������������������P890 Kelly, Conor ������������������������������������������������������P190 Kelly, John J. ��������������������������������������������������P2272 Kelly, Mark ��������������������������������������������������������P990 Kelrick, Michael I. ���������������������������������������������P851 Kemper, Sherri �����������������������������������������������P1656 Kenea, Aster ���������������������������������������������������P1798 Keniry, Megan E. ����������������������������������������������P290 Kenmotsu, Takahiro ������������������������������ P725,P2004 Kennard, Andrew S. �����������������������������������������P622 Kennedy, Anissa ���������������������������������������������P1608 Kennedy, Brendan ������������������������������������������P1840 Kennedy, Julie ������������������������������������ P1840,P1841 Kennedy, Lindsey �������������������������������������������P1651 Kennis, Bridget A. �������������������������������������������P1945 Kenny, Samuel J. �� P429,P932,P1008,P1484,P1894 Kenworthy, Anne K. ���������������������������� P1357,P1536 Kenyon, Cynthia �����������������������������������������������P745 Kerkvliet, Jason G. ���������������������� P60,P1263,P2444 Kern, Nadja ������������������������������������������������������P596 Keroles, Mark �������������������������������������������������P1562 Kerr, Alastair R. ����������������������������������������������P1029 Kerridge, Stephen ������������������������������������������P1575 Kershaw, Olivia �����������������������������������������������P2253 Kesisova, Ilona �����������������������������������������������P1719 Keski-Oja, Jorma K. �����������������������������������������P315 Kessler, Jonathan M. ��������������������������������������P1670 Kettenbach, Arminja ���������������������������� P199, P1393 Keum, Seula ��������������������������������������������������� P1159 Khachatoorian, Ronik �������������������������������������P1606 Khadilkar, Rohan ��������������������������������������������P2385 Khakurel, Amrita ������������������������ P688,P2328,P2454 Khalel, Ashjan F. ���������������������������������������������P1737 Khalil, Hadi �����������������������������������������������������P1497 Khalique, Umara ���������������������������������������������P1798 Khaliullin, Renat ��������������������������������� P1546,P1855 Khan, Amina �����������������������������������������������������P816 Khan, Anum ����������������������������������������������������P1457 Khan, Meraj H. ������������������������������������������ P72, P73 Khan, Muhammad J. ����������������������������������������P816 Khan, Tarique �����������������������������������������������������P43 Khandelwal, Nitesh K. ��������������������������������������P542 Khandelwal, Puneet �����������������������������������������P442 Khandjian, Edward ����������������������������������������� P1194 Khanna, Kanika ���������������������������������������� P35,P808 Khanna, Richa ������������������������������������������������P2026 Khater, Ismail ��������������������������������������������������P1661 Khatter, Divya �������������������������������������������������P1254 Khazanehdari, Kamal �������������������������������������P1927 Khedgikar, Vikram ������������������������������������������P1560 Khobrekar, Noopur V. ������������������������� P1773,P1815 Khodadai, Ryan ����������������������������������������������P1441

Khodjakov, Alexey ��������������������������������������������P204 Khodor, Yevgenia L. ��������������������������������������� P1163 Kholodenko, Boris ��������������������������������������������P717 Khor, GootHeah ����������������������������������������������P1962 Khrebukova, Irina ���������������������������������������������P890 Kianfard, Zohreh ���������������������������������������������P1096 Kida, Kazuki ���������������������������������������������������P2138 Kido, Larissa A. ����������������������������������������������P2308 Kido, Tatsuo ����������������������������������������� P286, P1965 Kiehart, Daniel P. ���������������������������������� P779,P2368 Kielbasa, Ondra M. ������������������������������� P833,P2477 Kieu, Zanett ������������������������������������������������������P479 Kihara, Takanori ����������������������������������������������P1730 Kikkawa, Masahide ����������������������������������������P1750 Kikkawa, Yamato �������������������������������� P2291,P2336 Kikuchi, Sakie ���������������������������������������������������P826 Kikushima, Kenji ���������������������������������������������P1041 Kikuti, Carlos ��������������������������������������������������P1862 Kilic, Fusun �����������������������������������������������������P2202 Kilmartin, John V. ��������������������������������������������P1074 Kim, Anthony ����������������������������������������������������P102 Kim, Bongjun ����������������������������������������������������P331 Kim, Byoung Choul �����������������������������������������P1462 Kim, Byung Chul ��������������������� P1932,P1933, P1152 Kim, Byung-Ju ��������������������������������������������������P568 Kim, Chae Eun �����������������������������������������������P1390 Kim, Chaekyun ��������������������������������������� P563,P564 Kim, Changhwan ��������������������������������������������P2398 Kim, Chowon ��������������������������������������������������P1564 Kim, Chungho ��������������������������������������� P651,P1647 Kim, Chuntae ��������������������������������������������������P2335 Kim, Dae I. ������������������������������������������������������P2027 Kim, Daehwan ������������������������������������������������ P1159 Kim, Dayoung �������������������������������������������������P1424 Kim, Deok-Ho �������������������������� P2259,P2285,P2286 Kim, Dong-Hwee ��������������������������������������������P2020 Kim, Dong Yeon ����������������������������������������������P1478 Kim, Dongyoung �������������������������������������������������P39 Kim, Eun K. ����������������������������������������������������P1628 Kim, Eun Hye ���������������������������� P688,P2328,P2454 Kim, Eun Jin ����������������������������������������� P651,P1647 Kim, Eun-Young �������������P752, P2430,P2431,P2432 Kim, GiJin ���������������������������������� P809,P1435,P1436 Kim, Haein ������������������������������������������������������P1901 Kim, Haemin ���������������������������������������������������P1374 Kim, Hak Rim ��������������������������������������������������P2133 Kim, Honesty ��������������������������������������������������P1423 Kim, Hong-Hee ������������������������������������� P331,P1374 Kim, Hyeon-Jin �����������������������������������������������P1664 Kim, HyeYun ���������������������������������������������������P2129 Kim, Hyo-Hyun �����������������������������������������������P1644 Kim, HyoJeong �����������������������������������������������P2133 Kim, Hyun- K. �������������������������������������������������P1561 Kim, Hyun-Ah �������������������������������������������������P1937 Kim, Hyung R. ����������������������������������� P1561, P2309 Kim, Hyun-Ji ����������������������������������������� P771,P2370 Kim, Hyunjoon ������������������������������������������������P1385 Kim, Hyunju ����������������������������������������������������P2071 Kim, Hyun-Yi ���������������������������������������������������P2448 Kim, Inki ����������������������������������������������������������P1092 Kim, In Young �������������������������������������������������P1095 Kim, Jaeook ����������������������������������������������������P1897 Kim, Jaeyeon ����������������������������������������������������P809 Kim, Jang Hee ������������������������������������������������ P1142 Kim, Jeong-Hoon ����������������������������������������������P474 Kim, Jeong-Yoon ����������������������������������������������P474 Kim, Ji Eon ����������������������������������������������������� P1162 Kim, Jihoon �����������������������������������������������������P2215 Kim, Jin-hoi �����������������������������������������������������P1514 Kim, Ji Woong ������������������������������������������������P1468 Kim, Ji-Ye ���������������������������������������������������������P474 Kim, Jiyoon ������������������������������������������� P651,P1647 Kim, Jong-Myung �������������������������������������������P2433 Kim, JongSik ����������������������������������������������������P184 Kim, Ju-Hwan �������������������������������������������������P2133 Kim, Jung-Ae ����������������������P268,P274,P567,P1930 Kim, Jung-Hyun ������������������������������������ P657,P1404 Kim, Jung-Wook �����������������������������������������������P331 Kim, Juwan �����������������������������������������������������P1567 Kim, Karam �����������������������������������������������������P2125 Kim, Ki-Chan ��������������������������������������������������P2433 Kim, KiSung ������������������������������������������������������P855 Kim, KiYun ��������������������������������������������������������P184 Kim, Kwanhee ��������������������������������������������������P747

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Kim, Kyeoung-Hwa �������������������������������������������P752 Kim, Kyoungtae ������������P1241,P1291,P2057,P2059 Kim, KyungKon �����������������������������������������������P1092 Kim, Kyung-Sup �����������������������������������������������P294 Kim, Laura Y. ������������������������������������������ P909,P957 Kim, MinCheol ������������������������������������������������P2225 Kim, Minhee ���������������������������������������������������P1027 Kim, MinJu ��������������������������������������������������������P184 Kim, MinJung ����������������������������������������������������P691 Kim, Nam-Hyung ������������������������������� P1739, P1740 Kim, Namoh ����������������������������������������������������P2461 Kim, Peter K. �������������������������� P2151, P2259,P2285 Kim, RangIe ������������������������������������������������������P564 Kim, SaLa �������������������������������������������������������P1947 Kim, Sang- H. �������������������������������������������������P2299 Kim, Sang Hoon ���������������������������������������������P1204 Kim, Sang Joon ����������������������������������������������P2357 Kim, Sang-Min ������������������������� P2430,P2431,P2432 Kim, Seon-Hwa ����������������������������������� P677, P2413 Kim, Seung-jae �����������������������������������������������P1514 Kim, Si-Oh ��������������������������������������������������������P825 Kim, Skylar X. �������������������������������������������������P1518 Kim, SoungMin �������������������������������������������������P856 Kim, So-Yeon ����������������������������������������������������P825 Kim, So-Young ������������������������������������������������P1092 Kim, Sumin �������������������������P461,P821,P823,P2380 Kim, Sung-Jin ���������������������������������������������������P107 Kim, Suree ������������������������������������������������������P1408 Kim, Tae ������������������������������������������������������������P597 Kim, Tae-Hyung ����������������������������������������������P1425 Kim, Tae Kyeong ��������������������������������������������P2347 Kim, Taekyung ������������������������������������������������P1905 Kim, Tak-Heun ������������������������������������������������P1581 Kim, Uh-Hyun ���������������������������������������������������P568 Kim, Wan-Ju ���������������������������������������������������P1255 Kim, We-Dae ��������������������������������������������������P2433 Kim, Won-Guen ����������������������������������������������P2335 Kim, Wook ������������������������������������������������������P1327 Kim, Yang Joon ������������������������������������������������P793 Kim, Yeajin ������������������������������������������������������P2262 Kim, Yeon Sook ������������������������������������������������P856 Kim, Yongbaek �������������������������������������������������P335 Kim, Yong-Gil ��������������������������� P2430,P2431,P2432 Kim, Yong-Hoon ���������������������������������������������P1645 Kim, Yong Jin ���������������������������������������� P754,P2296 Kim, Yoon Hee ��������������������������������������������������P184 Kim, Yoon Young ���������������������������������� P754,P2296 Kim, Young Ho �������������������������������������� P184,P1390 Kim, Young Hwa ��������������������������������������������� P1142 Kim, Young Hwan ���������������������������������������������P556 Kim, Young-Jun ����������������������������������������������P1645 Kim, Yumi �������������������������������������������������������P1871 Kim, Yun Hee ��������������������������������������������������P2446 Kim, Yun-Ho ���������������������������������������������������P2480 Kim, Yunhye ���������������������������������������������������P2299 Kimchi, Yoshiaki ���������������������������������������������P1322 Kimmig, Philipp �������������������������������������������������P712 Kimura, Hana �������������������������������������������������P1350 Kimura, Hiroshi �����������������������������������������������P2008 Kinch, Lisa ������������������������������������������ P2142,P2414 Kindberg, Abigail A. ����������������������������������������P1585 Kindsfather, Audrey ����������������������������������������P1200 King, Brianna R. ���������������������������������������������P1879 King, Colin ������������������������������������������������������P2209 King, Grant A. �������������������������������������������������P1215 King, Linda �����������������������������������������������������P1776 King, Nicole �������������������������������� P764, P777,P2353 King, Samantha J. ��������������������������������������������P388 King, Stephen J. ���� P122,P123,P1776,P1777, P124 King, Stephen M. ��������������������������������������������P1001 Kingsley, James L. ��������������������������������������������P728 Kinjo, Masataka ������������������������������������������������ P115 Kinoshita, Makoto �������������������������������������������P2122 Kintzer, Alexander F. ���������������������������������������P2081 Kiosses, William B. �����������������������������������������P2167 Kipreos, Edward T. �����������������������������������������P1024 Kira, Shintaro �������������������������������������� P1392,P2317 Kirby, Tyler J. ��������������������������������������������������P1221 Kirchenwitz, Marco �����������������������������������������P2084 Kirik, Viktor �������������������������������������������������������P982 Kirima, Junya ����������������������������������������������������P998 Kirimanjeswara, Girish S. ������������������ P1640, P2418 Kirmse, Robert ������������������������������������������� P33,P34 Kiseleva, Elena �������������������������������������������������P204

KissvonSoly, Szerenke �����������������������������������P1916 Kitagawa, Mayumi ��������������������������������������������P181 Kitano, Hisataka ����������������������������������� P682,P1655 Kitao, Hiroyuki ������������������������������������������������P1018 Kitsis, Richard ������������������������������������������������P1802 Kittel, Robert J. �������������������������������������������������P618 Kittisopikul, Mark ����������������������������������������������P597 Kizakeyil, Atish �������������������������������������������������P886 Klammer, Julia ������������������������������������������������P2371 Klaus, Colin J. ������������������������������������������������P1536 Klecker, Till �����������������������������������������������������P1256 Klein, Jonathon D. ��������������������������������������������P751 Klein, Robyn S. �����������������������������������������������P2423 Kleinman, Claudia ����������������������������������������������P52 Klenerman, David �������������������������������������������P2193 Klett, Anne ��������������������������������������������������������P629 Klimaviciusa, Linda �����������������������������������������P2381 Kliment, Corrine R. �����������������������������������������P2164 Kline, Ashley N. ������������������������������������������������P750 Klinkert, Kerstin ����������������������������������������������P1862 Klinman, Eva ��������������������������������������������������P1307 Klomp, Jennifer ���������������������������������� P1491,P2187 Klose, Christian �������������������������������������� P537,P541 Klosowiak, Julian L. ������������������������������������������P517 Kloxin, April M. ������������������������������������������������P1884 Klumperman, Judith �����������������������������������������P999 Knapp, Benjamin �������������������������������� P1858,P2217 Knecht, David A. ���������������������������������������������P2257 Knepper, Janice E. �����������������������������������������P1229 Kneussel, Matthias �����������������������������������������P1785 Knobeloch, Klaus-Peter ��������������������������������������P98 Knoten, Amanda �����������������������������������������������P155 Knox, Alan ������������������������������������������������������P2234 Knudson, Cheryl B. ����������������������������������������P1492 Ko, Ji-Ae ���������������������������������������������������������P1322 Ko, Jung-Jae ����������������������������������������������������P752 Ko, Panseon ��������������������������������������������������� P1159 Kobarg, Jorg ��������������������������������������������������� P1188 Kobashikawa, Shinko �������������������������������������P1089 Kobayashi, Hiroto �������������������������������������������P1652 Kobayashi, Isuzu ��������������������������������������������P2181 Kobayashi, Kazutoshi ���������������������������������������P876 Kobayashi, Miho �����������������������������������������������P383 Kobayashi, Misaki ������������������������������������������P2463 Kobayashi, Takeshi �������������������������������������������P787 Kobayashi, Takuya �����������������������������������������P1836 Koberling, Felix �����������������������������������������������P1658 Kobi, Priscilla ����������������������������������������������������P773 Koblinski, Jennifer ������������������������������������������ P1150 Koca, Yildiz �����������������������������������������������������P1571 Kocabay, Ahmet ����������������������������������������������P1553 Koch, André ����������������������������������������������������P1040 Koch, Bailey A. ������������������������������������������������� P211 Koch, Birgit �������������������������������������������������������P232 Kodani, Andrew T. �������������������������������������������P1572 Koenderink, Gijsje H. ��������������������������� P915, P1456 Koeppen, Hartmut ����������������������������������������������P63 Koerdt, Sophia N. �������������������������������������������P2070 Koes, David ����������������������������������������������������P1428 Koester, Darius V. ��������������������������������� P931,P2236 Koetsier, Jennifer L. ����������������������������������������P2356 Koffa, Maria ����������������������������������������������������P1719 Koffman, Jennifer S. �����������������������������������������P642 Kofler, Michael M. �������������������������������������������P2039 Koh, Duk-Su ���������������������������������������������������P1410 Koh, Eunjin �������������������������������������������������������P294 Koh, Yvette W. ������������������������������������������������ P1147 Kohana, Johar ������������������������������������������������P2144 Kohler, Jennifer J. �������������������������������������������P1370 Köhler, Katrin ����������������������������������������������������P412 Köhler, Simone ����������������������������������� P1874,P1875 Kohli, Priyanka �����������������������������������������������P1005 Kohrman, Abraham Q. �������������������������� P784,P1970 Kohrt, Sarah E. �����������������������������������������������P2182 Kohwi, Yoshinori ���������������������������������������������P2120 Kohwi-Shigematsu, Terumi �����������������������������P2120 Koike, Masato �������������������������������������������������P2074 Koiso, Yurika ���������������������������������������������������P1836 Kojima, Hiroaki �������������������������������������������������P998 Kokaji, Yoshito ������������������������������������������������P2473 Kokikian, Collette Y. ����������������������������������������P1270 Kolenbrander, Emily �����������������������������������������P166 Kolesnikov, Alexander ��������������������������������������P368 Kollasser, Jana �������������������������������� P85,P93,P2084

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Kollman, Justin M. ����������������������� P799,P803,P1724 Kolnik, Julie ����������������������������������������������������P2126 Kolotueva, Irina ������������������������������������������������P765 Komarov, Andrei ����������������������������������P1173,P2440 Komarova, Yulia A. �����������������������������������������P1474 Komianos, James �������������������������������������������P1709 Komori, Tomotaka ���������������������������������������������P857 Kon, Takahide �������������������������������������������������P1001 Kona, Srilakshmi D. ����������������������������������������P1405 Koncicka, Marketa ������������������������������������������P1047 Kondev, Jane ��������������������������������������������������P2014 Kondo, Yasushi �������������������������������������������������P598 Konen, Jessica �������������������������� P312,P1143,P1145 Kong, Deqing ����������������������������������������������������P964 Kong, Hyunkyung ���������������������������������������������P657 Kong, Shanshan ����������������������������������� P774,P1650 Kong, Xinyu ����������������������������������������������������P1476 König, Julia �����������������������������������������������������P2094 Konishi, Hideaki ����������������������������������������������P2047 Konishi, Satoshi ������������������������������������������������P641 Konomi, Mami ����������������������������������������������������P50 Kooiker, Kristina B. �������������������������������������������P943 Koomoa, Dana L. �������������������������������������������P1925 Kopach, Andrii ��������������������������������������������������P700 Kopinke, Daniel ������������������������������������������������P148 Kopp, Adam R. �������������������������������������������������P164 Kordon, Magdalena M. �����������������������������������P1238 Koren, Amnon �������������������������������������������������P2005 Korn, Edward D. �����������������������������������������������P965 Kornberg, Thomas ��������������������������������������������P938 Kornick, Kellianne �������������������������������������������P1535 Kortemme, Tanja ������������������������������������������������P69 Koscielny, Alicja ������������������������������������������������P475 Koshland, Douglas E. ��������������������������� P696,P1518 Kosinski-Collins, Melissa S. ���������������������������P1682 Koslover, Elena F. ��������������������������������� P913,P2409 Kosti, Idit ���������������������������������������������������������P2478 Kostow, Nora ��������������������������������������������������P1871 Kothari, Priyanka ��������������������������������������������P1861 Kotila, Tommi ����������������������������������������������������P925 Kotturi, Hari ������������������������������������������������������P281 Koubek, Emily ������������������������������������������������P1248 Kouprina, Natalay ���������������������������������������������P235 Koura, Minako ��������������������������������������������������P758 Kovacevic, Isomer ����������������������������������������������P44 Kovacs, Anthony P. �����������������������������������������P1670 Kovacs, Gabor G. �������������������������������������������P1785 Kovar, David R. ��P84,P100,P104,P891,P895,P907, ��������������������������������������������������������������������������P908 Kovary, Kyle M. ������������������������������������� P718,P1527 Kowalczyc, Christopher ����������������������������������P1562 Kowalski, Jeanne ������������������������������������������� P1143 Kowalski, Jennifer R. ��������������� P2126,P2127,P2128 Kowalyk, Steven ���������������������������������������������P1607 Koyama-Honda, Ikuko ������������������������������������P2074 Koyen, Allyson E. ���������������������������������������������P313 Koyoshi, Masatoshi ����������������������������������������P2304 Kozarova, Anna ����������������������������������������������P2194 Kozlowksi, Christopher �������������������������������������P976 Kozminski, Keith G. ����������������������������������������P2066 Kozono, Takuma �����������������������������������������������P379 Kraemer, Ben �������������������������������������������������P1658 Kraft, Lauren M. ������������������������������������ P524,P1345 Kramberger, Karl ��������������������������������������������P2144 Kramer, Adam H. ��������������������������������������������P1802 Kramer, Helmut ���������������������������������� P1506,P2321 Krämer, Oliver ������������������������������������������������P2271 Kramer-Zucker, Albrecht ���������������������������������P1432 Kranjec, Christian �������������������������������������������P1244 Krantz, Sarah E. ���������������������������������������������P2390 Krasowski, Pawel �������������������������������������������P1954 Kratz, Andrea ����������������������������������������������������P240 Kratz, Anne-Sophie ������������������������������������������P207 Krauss, Robert S. �������������������������������������������P2406 Kreienkamp, Hans-Jurgen ������������������������������P1439 kremneva, elena �������������������������������������������������P73 Krendel, Mira ��������������������������������������������������P1742 Krenning, Lenno ���������������������������������������������P1040 Kresch, Agnes K. ����������������������������������������������P685 Kretschmer, Simon �������������������������������������������P730 Kreyden, Victoria ��������������������������������������������P2127 Krieg, Anna �����������������������������������������������������������P6 Krieg, Michael ���������������������������������������������������P486 Krijgsveld, Jeroen �������������������������������������������P1227

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AUTHOR INDEX Krijnse-Locker, Jacomine �������������������������������P2412 Krishnamoorthy, Vidhya ����������������������������������P2025 Krishnamurthy, Chithra �������������������������������������P323 Krishnan, Arjun �����������������������������������������������P1545 Kroeger, Benjamin ��������������������������������������������P339 Kroeger, Cornelia ������������������������������������������� P1163 Krogan, Nevan ��������������� P152,P1179,P1686,P2411 Kroll, Torsten ��������������������������������������������������� P2113 Kromann, Emil B. �����������������������������������������������P55 Kroppen, Benjamin �������������������������������������������P521 Krummel, Matthew F. �������������������������������������� P1158 Kruse, Kevin J. �����������������������������������������������P1474 Krzewski, Konrad ���������������������������������������������P916 Kshitiz, . ���������������������������������������������������������� P1170 Ku, Seung-Yup ������������������������������������� P754,P2296 Kuan, CheeMun ���������������������������������������������P1689 Kubelka, Michal ����������������������������������������������P1047 Kubo, Ken-ichiro ���������������������������������������������P2344 Kucharavy, Andrei ���������������������������������������������P707 Küchlin, Sebastian ������������������������������������������P1432 Kudlyk, Tetyana ����������������������������������������������P2061 Kudo, Takamasa ���������������������������� P67,P740,P1629 Kudryashov, Dmitri S. ������������������������������� P78,P896 Kudryashova, Elena ��������������������������������� P78,P896 Kueblbeck, Moritz ���������������������������������������������P232 Kuhlman, Brian �����������������������������������������������P1800 Kuhn, Julia ������������������������������������������������������P1667 Kukreja, Alexander A. �������������������������������������P1913 Kulasekaran, Gopinath �������������������������������������P439 Kumar, Abhishek ������������������������������������������������P44 Kumar, Anita V. ���������������������������������������������������P76 Kumar, Brajesh �����������������������������������������������P1916 Kumar, K. Vijay �������������������������������������������������P452 Kumar, Rakesh ����������������������������������������������� P1115 Kumar, Sanjay ������� P314,P571,P922,P1484,P1951, ������������������������������������������������������������������������P2231 Kumari-Ilieva, Angeli ���������������������������������������P1330 Kumeta, Masahiro ������������������������������������������P2047 Kuna, Michael ���������������������������������������������������P759 Kunes, Kristina L. ���������������������������������������������P102 Kunttas-Tatli, Ezgi �������������������������������������������P2375 Kuntz, Jonathon �����������������������������������������������P781 Kunwar, Ambarish ��������������������������������������������P715 Kuo, Cheng-Chin �������������������������������������������� P1104 Kuo, Hsiao-Hui �����������������������������������������������P1082 Kuppers, Daniel A. ��������������������������������������������P788 Kurdistani, Siavash �����������������������������������������P2392 Kurilova, Svetlana ������������������������������������������P2445 Kurimoto, Masashi ������������������������������������������P2301 Kuriyan, John ���������������������������������������������������P598 Kurosaka, Santoshi ����������������������������������������P1732 Kurosawa, Yuri �����������������������������������������������P2052 Kuru, Erkin ��������������������������������������������������������P798 Kurubayashi-Shigetomi, Kaori ������������������������P1703 Kuruvilla, Heather G. ����������������������������������������P573 Kushiya, Akiho ������������������������������������ P2180,P2473 Kushmerick, Christopher ��������������������������������P1410 Kutchy, Naseer A. �������������������������������������������P2012 Kutlu, Hatice M. �������������������������������������� P282,P287 Kuwahara, Akela A. ����������������������������������������P1589 Kuwana, Tomomi ��������������������������������������������P2167 Kuzmanov, Aleksandra �����������������������������������P1033 Kvarnström, Sofie M. ��������������������������������������P1330 Kwabena, Seshie O. ���������������������������������������P1608 Kweon, HyaeYon ��������������������������������������������P2345 Kwiat, Jonathan ����������������������������������������������P2422 Kwiatkowski, Adam V. ������������������������� P1469,P1481 Kwok, Benjamin H. �����������������������������������������P1866 Kwon, Ahreum ������������������������������������������������ P1159 Kwon, Gi Hyun �����������������������������������������������P1390 Kwon, Hyog Young �������������������������������������������P300 Kwon, Ilmin �������������������������������������������������������P625 Kwon, Jeongwoo ��������������������������������������������P1556 Kwon, Junyeob �����������������������������������������������P1091 Kwon, Kyoo-Ri ������������������������������������������������P1646 Kwon, Lois ������������������������������������������������������P1847 Kwon, MiRi �����������������������������������������������������P1095 Kwon, Mookwang �������������������������������������������P1567 Kwon, Sunghoon ��������������������������������������������P2259 Kwon, Yeong Min ����������������������������������������������P564 Kwon, Young ��������������������������������������������������P2207 Kyger, Ryan ����������������������������������������������������P1028

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L.Rosales, Jesusa ������������������������������������������P1347 Laakkonen, Pirjo �����������������������������������������������P315 Laakso, Joseph ������������������������������������������������P959 Laakso, Meg M. ��������������������������������������������������P27 LaBaer, Joshua ����������������������������������������������P2425 Laband, Kimberley A. �������������������������������������P1904 LaBarge, Mark A. ������������������������������� P2229, P2300 Labbé, Jean-Claude ������������������������������� P176,P247 Labouesse, Michel �����������������������������������������P1550 LaBute, Brayden C. ������������������������������������������P303 Lac, Diana ������������������������������������������������������P2435 Lacasa, Cristina �������������������������������������� P970,P975 Lacefield, Soni ������������������������������������ P1046,P1048 Lackner, Laura L. ���������������������������������� P524,P1345 Lacourt, Mercedes Y. ��������������������������������������P1949 Ladds, Marcus ������������������������������������������������P1893 Laderman, Bezia ����������������������������������������������P245 Ladinsky, Mark S. ���������������������������������������������P498 Ladoux, Benoit �����������������������������������������������P1471 Laferney, Brianna K. �����������������������������������������P671 LafitaNavarro, MariadelCarmen �����������������������P292 Laflamme, Guillaume �������������������������������������P1866 Lagerman, Makayla B. �������������������������������������P220 Lagos-Cabré, Raúl �����������������������������������������P1422 Lagraulet, Adriana ��������������������������������������������P875 Lagrée, Valérie ���������������������������������������������������P95 Lahav, Galit ���������������������������� P1083, P1084, P1175 Lahtinen, Taina �����������������������������������������������P1333 Lai, Cary ���������������������������������������������������������P1586 Lai, Frank �������������������������������������������������������P2253 Lai, Hoyin ����������������������������������������������� P872,P873 Lai, Ming-Derg ������������������������������������������������P1964 Lai, Nicole ���������������������������������������������������������P910 Lai, San-Huei ��������������������������������������������������P1544 Lai, Yung-Chi ����������������������������������������������������P760 Lai, Yun-Ju ������������������������������������������������������P1924 Lai, Zhi-Chun ����������������������������������������������������P561 Lain, Sonia �����������������������������������������������������P1893 Lajoie, Gilles A. �����������������������������������������������P1389 Lajoie, Patrick ����������������������������������������� P698,P706 LaJoie, Dollie ����������������������������������������������������P496 Lakaye, Bernard ���������������������������������������������P2343 Laketa, Vibor ��������������������������������������������������P2092 Lakins, Johnathon N. ��������������������������������������P2373 Lakisic, Goran ������������������������������������������������P1979 Lakkaraju, Aparna ������������������������������������������P1275 Lakoduk, Ashley M. ����������������������������������������P1243 Lakonishok, Margot ����������������������������������������P1760 Lakshminarayanan, Sowmya �������������������������P1325 Lam, Christoffer H. �����������������������������������������P2285 Lam, Hui Yue Monatrice �����������������������������������P598 Lam, Jason �������������������������������������������������������P516 Lam, Jonathan ������������������������������������������������P1733 Lam, Mable ������������������������������������������� P675,P2154 Lamason, Rebecca ����������������������������������������P2214 Lamaze, Christophe ����������������������������� P619,P2236 Lamb, Helen ���������������������������������������������������P1554 Lambert, Herman ���������������������������������������������P693 Lambert, Stephen �������������������������������������������P2377 Lambert de Rouvroit, Catherine ���������������������P1354 Lambowitz, Alan �����������������������������������������������P354 Lambrus, Bram G. ������������������������������������������P1037 Lamela, Gustavo ��������������������������������������������P1923 Lamkin, Elizabeth R. ��������������������������������������P1473 Lammerding, Jan ����������������������� P375,P1102,P1221 Lammers, Lindsay G. �������������������������������������P1772 Lamond, Angus ����������������������������������������������P1676 Lampe, Marko ��������������������������������������������������P232 Lampe, Paul D. �����������������������������������������������P2283 Lampson, Michael A. ����������������� P249,P1058,P1063 Lamson, Adam �����������������������������������������������P1020 Lan, Matthew ����������������������������������������������������P348 Lan, Tian ���������������������������������������������������������P2261 Lan, Xi ������������������������������������������������������������P2131 Landahl, Eric C. ����������������������������������������������P1882 Landerholm, Thomas E. �����������������������������������P839 Landmann, Cedric ������������������������������� P1856, P198 Landor, Sebastian ��������������������������������������������P628 Landry, Marc ���������������������������������������������������P1785 Lane, Keara �������������������������������������������� P67,P1629 Lane, Simon I. ��������������������������������������������������P228 Lanfranco, MariaFe ����������������������������������������P2339

Lang, Charles F. �����������������������������������������������P453 Lang, Roland �������������������������������������������������� P1168 Lang, Yaw-Dong ���������������������������������������������P1982 Lange, Ingo ����������������������������������������������������P1925 Lange, Jeffrey J. �����������������������������������������������P699 Lange, Stephan ����������������������������������������������P1526 Langenhan, Tobias �������������������������������������������P618 Langfald, Alyssa K. �������������������������������������������P222 Langouras, Christos �����������������������������������������P923 Lanman, Jason K. ������������������������������������������P1601 Lantoine, Josephine ���������������������������������������P2290 Laos, Triin ���������������������������������������������������������P214 Laporte, Amanda ��������������������������������������������P2314 Lappalainen, Pekka �����������P73,P1741,P2268, P925 Larabell, Carolyn A. ���������������������������� P1667,P2325 Lara-Martínez, Reyna �������������������������������������P1234 Lara Ribeiro, Priscilla R. ��������������������������������� P1164 Laredo Cisneros, MarcoSamuel ���������������������P2041 Larionov, Vladimir ���������������������������������������������P235 LaRiviere, Patrick �������������������������������������������P1669 Larocque, Gabrielle ����������������������������������������P1271 La Rocque, Jeannine R. ���������������������������������P2001 Larocque, Kevin �����������������������������������������������P769 Larrimore, Katherine E. ���������������������������������� P1192 Larschan, Erica N. ������������������������������������������P1232 Larsen, Lars A. �������������������������������������������������P146 Larsen, Melinda ������������������������������������������������P761 Larson, Austin ���������������������������������������������������P412 Larson, Ben T. ������������������������������������������������P2353 Larson, Brad ���������������������������������������������������P1088 Larson, Braden J. �������������������������������������������P1033 Larson, Daniel R. �������������������������������������������� P1176 Larson, Matthew E. ����������������������������������������P2177 Larue, Lionel ���������������������������������������������������P1288 LaRussa, Marie F. ��������������������������������������������P860 LaRusso, Nicholas F. ��������������������������������������P2150 Lasek, Amber L. �����������������������������������������������P193 Lasheras, Juan C. ������������������������������� P729, P1489 Lasker, Keren ���������������������������������������������������P595 Latgé, Bruno ���������������������������������������������������P1756 Lau, PikKi ������������������������������������������ P1285, P1296 Lau, ShunYunn �������������������������������������������������P421 Lau, Yun-Fai C. ������������������������������������� P286,P1965 Laugks, Ulrike ���������������������������������������������������P400 Laurent, Estelle M. �������������������������������������������P321 Lautenschlaeger, Franziska �����������������������������P376 Lavoie, Josée N. �����������������������������������������������P693 Law, Andy ������������������������������������������� P1367,P1680 Law, Kelsey B. ������������������������������������������������P2151 Law, SzeMing ���������������������������������������������������P747 Lawas, Maria ��������������������������������������������������P1433 Lawrence, Kenneth F. �������������������������������������P2188 Lawrence, Rosalie ������������������������������������������P1674 Lazar, Alexander J. �������������������������������������������P296 Lazennec-Schurdevin, Christine ��������������������P1979 Le, NhatTu ������������������������������������������������������P2198 Le, Phuong �������������������������������������������������������P910 Leaf, David S. �������������������������������������������������������P9 Leal, Andrés F. ������������������������������������� P406, P1621 Leal-Orta, Elizabeth ����������������������������������������P1440 Leary, Allen Y. �������������������������������������������������P1023 Leaver, Tim �������������������������������������������������������P884 Lebedev, Maxim I. ����������������������������������������������P60 Lebensohn, Andres M. �������������������������������������P559 LeBert, Danny C. ��������������������������������������������P1501 LeBivic, Andre ���������������������������������������� P451,P763 LeBlanc, Andrea C. ������������������������������������������P678 Leblanc, Emmanuelle �������������������������������������P2402 Leblanc, Valérie ����������������������������������������������P2212 Lebofsky, Ronald ����������������������������������������������P890 Le Borgne, Rémi �������������������������������������������� P2115 Le Borgne, Roland ������������������������������� P765,P2218 Lechtreck, Karl F. �������������������������������� P1010,P1842 Leckband, Deborah ����������������������������������������P1476 Le Claire, Lawrence L. �����������������������������������P1723 Lecona, Emilio ������������������������������������������������P1051 Lecuit, Thomas ������������������������������������� P451,P1575 Ledray, Aaron �������������������������������������������������P1777 Lee, Aesin ���������������������������������������������������������P683 Lee, Ah Young ��������������������������������������������������P203 Lee, Albert A. ����������������������������������������������������P716 Lee, Boram ����������������������������������������������������� P1311 Lee, Chia-Yun ���������������������������������������������������P697 Lee, Chung T. �������������������������������������������������P1666

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Lee, Deanna C. ����������������������������������������������P1290 Lee, DongGun ��������������������������������������������������P804 Lee, DongMin �������������������������������������������������P1095 Lee, Ethan ��������������������������������������������������������P559 Lee, Eun K. �����������������������������������������������������P2398 Lee, Eun Ah ����������������������������������������������������P2398 Lee, Eung-Seok ������������������������������������������������P567 Lee, Eun-Jin ���������������������������� P2430,P2431,P2432 Lee, Eunjung ����������������������������������������������������P549 Lee, Eun-Jung ������������������������������������������������P2455 Lee, EunKyung �����������������������������������������������P1327 Lee, Fang J. ������������������������������ P899,P1427,P1791 Lee, Frank Y. ��������������������������������������������������P1270 Lee, HaNeul(Skott) ����������������������������������������� P1190 Lee, HansongI ������������������������������������������������P1646 Lee, Hwa Y. ����������������������������������������������������P2309 Lee, Hye E. �����������������������������������������������������P2428 Lee, Hye-Jin ��������������������������������������� P1381,P1382 Lee, HyeSun �����������������������������������������������������P556 Lee, Hyun O. ����������������������������������������������������P700 Lee, Hyun-Kyung ��������������������������������������������P1564 Lee, Hyunna T. �������������������������������������������������P909 Lee, Hyun-Shik ����������������������������������� P1563,P1564 Lee, I-Ju �����������������������������������������������������������P189 Lee, Il-Hyung ��������������������������������������������������P2093 Lee, Intaek ��������������������������������������������������������P427 Lee, Jae-Ho �������������������������������������������� P225,P250 Lee, Jaehyeon ������������������������������������������������P1649 Lee, Jae-Yong ��������������������������������������������������P330 Lee, Jen-Yi ���������������������������������������������������������P37 Lee, Jeong-Chae ��������������������������������������������P1581 Lee, Jeonghwan ����������������������������������� P677,P2413 Lee, Jin Kyung ��������������������������������������������������P295 Lee, Ji Young ��������������������������������������������������P1390 Lee, Joanna Y. ��������������������������������������������������P606 Lee, Joo Young �����������������������������������������������P2428 Lee, Justin H. �������������������������������������������������P2286 Lee, Ju Youn ���������������������������������������������������P2461 Lee, Kian-Yong ����������������������������������� P1863,P1902 Lee, Ki-Young �������������������������������������������������P1347 Lee, Kwangmin �����������������������������������������������P1378 Lee, Kwonmoo �������������������������������������������������P107 Lee, Kyung-Ah ��������������������������������������������������P752 Lee, Lisa ���������������������������������������������������������P2143 Lee, Michael ���������������������������������������������������P2120 Lee, Mi-Hye ���������������������������������������������������� P1131 Lee, MiJeong ��������������������������������������������������P1375 Lee, MiNi ��������������������������������������������������������P2345 Lee, NaYoung �������������������������������������������������P2196 Lee, Philbert ���������������������������������������������������P2391 Lee, Robin E. ����������������������������������������������������P558 Lee, Samuel A. �����������������������������������������������P1632 Lee, SangHan ���� P825,P1644,P1645,P1646,P2433 Lee, Sang-Hyun �����������������������������������������������P181 Lee, Sang-Kyu ��������������������������������������������������P278 Lee, SangShin ��������������������������������������������������P809 Lee, Seo-Ho �����������������������������������������������������P568 Lee, Seok Hyun ����������������������������������������������P1645 Lee, Seul ��������������������������������������������������������P2433 Lee, Sherry �����������������������������������������������������P1449 Lee, Shih-Jong J. ����������������������������������� P872,P873 Lee, So Min ���������������������������������������������������� P1108 Lee, So Ra ����������������������������������������� P1093,P2205 Lee, Stacey ������������������������������������������������������P922 Lee, Steven ����������������������������������������������������P2193 Lee, Suk Keun ��������������������������������������������������P856 Lee, Sung Sik ���������������������������������������������������P717 Lee, Sungsoo ���������������������������������������������������P597 Lee, Sun-Kyung ������������������������������������������������P742 Lee, Su-Yeon ����������������������������������������������������P752 Lee, Suzanne R. ���������������������������������������������������P9 Lee, Sylem �������������������������������������������������������P324 Lee, Teresa �������������������������������������������������������P834 Lee, Vanessa R. ���������������������������������������������P2272 Lee, Wei-Chia �������������������������������������������������P2399 Lee, Wei-Lih ���������������������������������������������������P1771 Lee, Won J. ����������������������������������������������������P1628 Lee, Wonjong ���������������������������������������������������P804 Lee, Yeon-Ju ��������������������������������������������������P2340 Lee, Yi-Fen �������������������������������������������������������P327 Lee, Yi-Hsuan ���������������������������������������������������P697 Lee, Yin Loon ���������������������������������������������������P988 Lee, Yong Deok ����������������������������������������������P1374 Lee, Yoonjoo K. ����������������������������������������������P2273

Lee, You Jin ����������������������������������������������������P1533 Lee, Young-Kwang ������������������������������� P598,P1398 Lee, Young-suk �����������������������������������������������P1545 Lee, Yuh-Ru ����������������������������������������������������P1889 Lee, Yu-Jeong ���������������������������������������� P274,P567 Lee, Yu Jin ������������������������������������������������������ P1129 Lee, Yu Shin �����������������������������������������������������P294 Lee, Zang H. �����������������������������������������������������P331 Lee, MidEum E. ������������������������������������ P468,P1393 Lee-Estevez, Manuel ����������������������������������������P684 Leem, Young-Eun �������������������������������������������P2370 Lee-Rivera, Irene ��������������������������������������������P2199 Lees, Joshua A. ������������������������������������������������P535 Lee-Soety, Julia Y. ��������������������������������������������P349 Lefebvre, Celine ��������������������������������������������� P1153 Lefebvre, Louis �������������������������������������������������P649 Lefrancois, Stephane ��������������������������� P433,P1286 Legant, Wesley R. ���������������������������������� P48,P2139 Le Grand, Marion �������������������������������������������P2451 Le Gros, Mark A. �������������������������������� P1667,P2325 Lehmann, Katherine S. �����������������������������������P1253 Lehtimaki, Jaakko ���������������������������������������������P925 Lei, Kai �����������������������������������������������������������P2389 Lei, Mingxing ����������������������������������������������������P760 Leidal, Andrew M. ������������������������������� P2077,P2083 Leijnse, Natascha �������������������������������������������P2225 Leimkuehler, Silke ��������������������������������������������P216 Lein, Pamela J. ��������������������������������������� P355,P581 Leiva-Salcedo, Elías ���������������������������������������P1437 Lele, Tanmay P. ����������������������������������������������P1220 Lelievre, Sophie A. �����������P334,P631,P1235,P1236 LeMarois, Marguerite �������������������������������������P2125 Lemaster, Elizabeth ����������������������������������������P1377 Lemberger, Thomas ���������������������������������������P1541 Lemestr, Audrey ���������������������������������������������P2402 Lemke, Edward ���������������������������������� P1658,P2050 LeMoigne, Ronan �������������������������������������������P1916 Lénárt, Péter ���������������������������������������������������P2024 Lencer, Wayne I. ���������������������������������������������P1357 Lendahl, Urban �������������������������������������������������P519 Lengyell, Tess C. �������������������������������������������� P2113 Lenne, Pierre-François ��������������������������� P451,P763 Lennon-Dumenil, Ana-Maria �����������������������������P376 Lentucci, Claudia �������������������������������� P1375,P1566 Leo, Lanfraco �������������������������������������������������P1320 Leof, Edward B. ������������������������������������ P467,P2150 Leonard, Thomas �������������������������������������������P1406 Leonel, DouglasAlexandre �����������������������������P1565 Leonel, EllenCristina R. ����������������������������������P1565 Leonhardt, Heinrich ����������������������������������������P2016 Leray, Aymeric ������������������������������������������������P1480 Lerche, Martina ������������������������������������������������P650 Lereaux, Guillaume ����������������������������������������P2302 Lerit, Dorothy A. ������������������������������������������������P213 Lerner, Mitchell �����������������������������������������������P2334 Leroux, Michel R. ��������������������������������� P152,P1840 Leschziner, Andres E. �������������������������������������P1765 Leskau, Miriam �������������������������������������������������P260 Lesko, Alyssa C. ������������������������������������P464,P1125 Lesko, Elizabeth M. ������������������������������������������P561 Leskoske, Kristin L. ����������������������������������������P2189 Lester, Daniel �������������������������������������������������P2128 Letellier, Mathieu ��������������������������������������������P2280 Leu, Nicolae A. ����������������������������������� P1387,P2352 Leu, Steve ������������������������������������������������������P2399 Leung, Anthony K. ������������������������������������������P1635 Leung, Edison ��������������������������������������������������P601 Leung, Jacqueline M. ��������������������������� P989,P1081 Leung, Wilson �����������������������������������������������������P27 LeValley, Paige J. �������������������������������������������P1884 Levchenko, Andre ������������������������������������������� P1170 Levdikov, Vladimir M. ��������������������������������������P1399 Levental, Ilya ����������������������P541,P543,P544,P1355 Levental, Kandice R. ������������������� P541,P544,P1355 Levi, Stephanie K. ����������������������������������������������P20 Levitan, Edwin S. ��������������������������������������������P1312 Levitan, Irena ��������������������������������������������������P1377 Levy, Daniel L. ������� P364,P378,P505,P1217,P2022, ���������������������������������������������������P378,P2036,P1444 Levy, Ezra �������������������������������������������������������P1679 Levy, Oren A. ��������������������������������������������������P1323 Lew, Daniel J. ���������������������������������������������������P454 Lew, Helen ��������������������������������������������������������P809 Lewellyn, Lindsay ����������������������������������� P749,P750

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Lewis, Arielle ��������������������������������������������������P2135 Lewis, Cody W. �������������������������������������������������P272 Lewis, Jani E. ����������������������������������������� P297,P298 Lewis, Jaston �� P1494,P1917,P1919, P1918, P1922 Lewis, John ������������������������������������������������������P316 Lewis, Linda �����������������������������������������������������P530 Lewis, Nichole ������������������������������������������������P1028 Lewis, Richard S. �������������������������������������������P1747 Lewis, Samantha C. ����������������������������� P520,P1328 Leyton, Lisette ������������������������������������ P1422,P2243 Leyva, Kathryn J. ��������������������������������������������P2263 Li, Amanda M. ������������������������������������������������ P2113 Li, Amy ��������������������������������������������������������������P951 Li, Bing �����������������������������������������������������������P1059 Li, Boyang ������������������������������������������������������P2179 Li, Chun C. �����������������������������������������������������P1791 Li, Chunlei ������������������������������������������������������P1812 Li, Chunliang ��������������������������������������������������P1963 Li, Chunman �����������������������������������������������������P441 Li, David W. ����������������������������������������������������P1380 Li, Deyu ���������������������������������������������������������� P1155 Li, Dong �������������������������������������� P87, P1712,P2139 Li, Elizabeth C. �������������������������������������������������P570 Li, Fei ��������������������������������������������������������������P2013 Li, Feng-Qian ��������������������������������������������������P1825 Li, Guodong ����������������������������������������������������P1637 Li, Hongzhe ������������������������������������������������������P827 Li, Huaibiao ���������������������������������������������������� P2113 Li, Je-Luen ������������������������������������������������������P1670 Li, Jin ����������������������������������������������������������������P827 Li, Jingyu ����������������������������������������������������������P151 Li, Kevin ����������������������������������������������������������P2014 Li, Liang ����������������������������������������������������������P1579 Li, Lydia ����������������������������������������������������������P1372 Li, Mingang �������������������������������������������������������P125 Li, Mingxi ����������������������������������������������������������P297 Li, Peiyao ��������������������������������������������������������P1358 Li, Qiaochu ��������������������������������������������� P122,P123 Li, Renyu ����������������������������������������������������������P934 Li, Rong ����������������������������P185,P707,P1843,P2102 Li, Shang ����������������������������������������������������������P854 Li, Shiwei ����������������������������������������������������������P547 Li, Siyang ����������������������������������������������������������P427 Li, Tiansen ������������������������������������������������������P1786 Li, Tun �������������������������������������������������������������P1319 Li, Wan-Ju ������������������������������������������������������ P1156 Li, Weihan ���������������������������������������������������������P712 Li, Wen ����������������������������������������������������������� P1143 Li, Xiaogang �����������������������������������������������������P157 Li, Xiaoyan ��������������������������������������������������������P157 Li, Yan ���������������������������������������������������������������P183 Li, Yang �����������������������������������������������������������P2013 Li, Yanjiao �������������������������������������������������������P1955 Li, Yanyang �����������������������������������������������������P1582 Li, Yichen ��������������������������������������������� P873, P1379 Li, Younan ���������������������������������������������������������P109 Li, Yu ������������������������������������������P667,P1584,P2400 Li, Yuanyuan ���������������������������������������������������P2391 Li, Yun R. ����������������������������������������������������������P827 Li, Yunmin ����������������������������������� P286,P1965, P333 Li, Zhipeng ��������������������������������������������������������P435 Liang, Cindy ���������������������������������������������������P1316 Liang, Fengxia ��������������������������������������������������P504 Liang, Liang ������������������������������������������������������P578 Liang, Qiren ����������������������������������������������������P1955 Liang, Shu-Man ���������������������������������������������� P1104 Liang, Winnie H. �����������������������������������������������P122 Liang, Xiaomin ����������������������������������������������������P38 Liang, Xing �����������������������������������������������������P2362 Liang, Xue-hai �������������������������������������� P410,P1240 Liang, Yan �������������������������������������������������������P2266 Liang, Yinwen ��������������������������������������� P153,P1816 Liao, Meng-Lin ��������������������������������������������������P487 Liao, Ruiqi ������������������������������������������������������P2018 Liao, Wei-Hao �������������������������������������������������P1450 Liao, Yen-Lun ���������������������������������������������������P253 Liao, Yi-Hua ������������������������������������������������������P512 Libanje, Fotine ������������������������������������������������ P1153 Libin, Yuan ����������������������������������������������������������P41 Liburd, Shakilah M. ����������������������������������������� P1611 Lidke, Diane S. �����������������������������������������������P1418 Lidke, Keith A. ��������������������������������������������������P586 Lie, Wen-rong �������������������������������������������������P2183 Lieberman, Marya ��������������������������������������������P731

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AUTHOR INDEX Lieberman, Verna(Rose) ��������������������������������P2265 Liechti, Robin ��������������������������������������������������P1541 Lieux, Molly E. ������������������������������������������������P1222 Ligon, Lee �������������������������������������������������������P1793 Lilja, Johanna �������������������������������������������������P1439 Lilla, Sergio �����������������������������������������������������P1979 Lillya, Mark ����������������������������������������������������� P1311 Lim, Amanda ������������������������������������������������������P97 Lim, Andrea R. ��������������������������������������������������P788 Lim, Dae-Sik �����������������������������������������������������P474 Lim, Eileen ������������������������������������������������������P1616 Lim, Hooi Cheng ���������������������������������������������P1860 Lim, James ��������������������������������������������� P333,P867 Lim, JiEun ������������������������������������ P461,P823,P2380 Lim, John S. ���������������������������������������������������P1214 Lim, Kyun S. ���������������������������������������������������P1955 Lim, Roderick Y. ����������������������������������������������P2037 Lim, Samuel �����������������������������������������������������P174 Lim, Sanghee �������������������������������������������������P2197 Lim, SeiHien ���������������������������������������������������P1689 Lim, Steve �������������������������������������������� P657,P1404 Lim, Sun Ki �����������������������������������������������������P2398 Lim, Sun Young ����������������������������������������������P1976 Lim, Swee S. ������������������������������������� P1326, P1335 Lim, Wendell ��������������������������������������������������� P1122 Lim, Yun-Ji �������������������������������������������� P677,P2413 Lima, Maíra D. �������������������������������������P1149,P1165 Lima Da Silva, Eulalia Maria ����������������� P239, P236 Limozin, Laurent �����������������������������������������������P929 Lin, Athena �����������������������������������������������������P1892 Lin, Chao-Chieh �����������������������������������������������P181 Lin, Charles ������������������������������������������������������P890 Lin, Chia-Jung ��������������������������������������������������P256 Lin, Chien-Han �����������������������������������������������P1450 Lin, Chien-Hong ���������������������������������� P616, P1468 Lin, Chin-Hsien �����������������������������������������������P2158 Lin, ChunHan �������������������������������������������������P2300 Lin, Chun-Yu ���������������������������������������������������P1000 Lin, George �����������������������������������������������������P1951 Lin, Hsiao C. ���������������������������������������������������P2415 Lin, Hsi-Hui �������������������������������������������������������P299 Lin, Hsiu-Kuan ��������������������������������������������������P299 Lin, Huawen �������������������������������������� P1002, P1670 Lin, Jing ������������������������������������������������������������P882 Lin, Joy �����������������������������������������������������������P1947 Lin, Ling-Li ������������������������������������������������������P1462 Lin, Mary G. ���������������������������������������� P2316,P2323 Lin, Ryan ��������������������������������������������������������P1221 Lin, Shan-Shan �������������������������������������������������P921 Lin, Shen ��������������������������������������������������������P1783 Lin, Shengchen ������������������������������������������������P893 Lin, Shin J. ������������������������������������������������������P1791 Lin, Tain-Zan �����������������������������������������������������P689 Lin, Tzu-yin �������������������������������������������������������P277 Lin, Yi ����������������������������������������������������������������P625 Lin, Yi-Nan ��������������������������������������������������������P209 Lin, Yi-Ting ������������������������������������������������������ P1104 Lin, Yi-Tzu ��������������������������������������������������������P790 Lin, Yu-Chiao �������������������������������������������������� P1135 Lin, Yu-Chun ����������������������������������������� P716,P1000 Linares, Gabriel R. �������������������������������������������P872 Linder, Stefan ��������������������������������������P1250,P1711 Lindow, Norbert ������������������������������������������������P240 Lindquist, Nathan C. ���������������������������������������P1662 Lindsey, Angus �����������������������������������������������P1715 Ling, Taotao ����������������������������������������������������P1923 Lingappa, Vishwanath R. ��������������������������������P1372 Linke, Marco ����������������������������������������������������� P611 Linklater, Erik S. �����������������������������������������������P310 Liou, Jen �����������������������������������������������������������P536 Liou, Jun-Yang ������������������������������������������������ P1104 Lipiec, Monika ������������������������������������������������P1954 Lipiniski, Nathan ���������������������������������������������P1623 Lipp, Jesse J. ������������������������������������������������� P1179 Lippincott-Schwartz, Jennifer ����� P48,P2095,P2143, �������������������������� P2145,P2325,P1665,P1834,P2139 Lipton, David ���������������������������������������������������� P114 Liro, Małgorzata J. ������������������������������������������ P2110 Lis, Elizabeth ����������������������������������������������������P575 Lishko, Polina V. ����������������������������������� P756,P1008 Liszewska, Ewa ������������������������������������������������P475 Litchfield, David W. ����������������������������� P1389,P2457 Litwa, Karen A. �����������������������������������������������P2123 Liu, Allen P. ������������������������������������������� P390,P2096

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Liu, Andrea J. �������������������������������������������������P1228 Liu, Bo ������������������������������������������������������������P1889 Liu, Chao ����������������������������������������������������������P943 Liu, Dianyi �������������������������������������������������������P2048 Liu, Gaowen ���������������������������������������������������P1214 Liu, Guojun �����������������������������������������������������P1759 Liu, Hung Ching ����������������������������������������������P2296 Liu, Jennifer Y. ������������������������������������������������P2077 Liu, Jian ��������������������������������������������� P1539, P2242 Liu, Jie ��������������������������������������������������������������P884 Liu, Jing ������������������������������������������������ P385,P1236 Liu, Jun ������������������������������������������������� P989,P1081 Liu, Li-Ka ��������������������������������������������������������P1329 Liu, Min �������������������������������������������������������������P413 Liu, P.W. ����������������������������������������������������������P1842 Liu, Qingyang �������������������������������������������������P2358 Liu, Shasha ����������������������������������������������������P1620 Liu, Shengquan ������������������������������������������������P279 Liu, Shijie ����������������������������������������������������������P432 Liu, Songtao ���������������������������������������������������P1026 Liu, Song-Tao ������������������������������������������������� P1172 Liu, Tong �����������������������������������������������������������P519 Liu, Tsung-Li �����������������������������������������������������P103 Liu, Wanli ��������������������������������������������������������P2221 Liu, Weizhe �����������������������������������������������������P1584 Liu, Xing ����������� P195, P1752,P1792,P1984, P1908 Liu, Xiong ���������������������������������������������������������P965 Liu, Yajun ����������������������������������������������������������P189 Liu, Yangmingyue ���������������������������������������������P545 Liu, Yanxia ��������������������������������������������������������P860 Liu, Ya-Wen ������������������������������� P921,P1451,P2360 Liu, Yi ����������������������������������������������������������������P163 Liu, Ying ������������������������������������������������������������P413 Liu, Yizhi ���������������������������������������������������������P1380 Liu, Yuqiong ����������������������������������������������������P2152 Liu, Yuzhou �����������������������������������������������������P2337 Liu, Zhichao ����������������������������������������������������P2305 Livingston, Kamren �����������������������������������������P1054 Lizano, Marcela ����������������������������������������������P1244 Lizio, Marina ���������������������������������������������������P2008 Llomparr, Diana ����������������������������������������������P1053 Lloyd, Thomas E. ��������������������������������������������P2035 Lo, Wing-Cheong C. �����������������������������������������P468 Lobert, Sharon ��������������������������������������������������P271 Lobingier, Braden �������������������������������������������P1686 Lobjois, Valerie �����������������������������������������������P1971 Lockery, Shawn R. ������������������������������������������P2464 Loew, Damarys �����������������������������������������������P1073 Loewen, Christopher J. ������������������������������������P553 Logan, Todd ����������������������������������������������������P1294 Logemann, Enno ����������������������������������������������P346 Login, Frédéric H. ���������������������������������������������P642 Logsdon, Glennis A. ���������������������������������������P1062 Logue, Jeremy ������������������������������������������������P2145 Long, Alexandra F. ������������������������������P1161, P1911 Longhini, AnaLeda ��������������������������������������������P658 Lopacinski, Amanda ���������������������������������������P1566 Loperena, Yaliz ������������������������������������� P276,P1949 Lopes, Helena B. �������� P659,P814,P817,P818,P889 Lopes, Joseph ��������������������������������������������������P121 Lopez, Alma ������������������������������������������������������P290 Lopez, Luis A. �������������������������������������������������P1053 Lopez, Pablo ��������������������������������������������������P1949 López-Colomé, AnaMaría �������������������������������P2199 LopezCoral, Alfonso ���������������������������������������P2062 Lopez-Hernandez, Edith C. ����������������������������P2199 Lopez Murillo, Teresa Del Carmen �������������������P463 Lopez-Rivera, Amy �����������������������������������������P2341 Lord, Matthew J. �����������������������������������������������P100 Lord, Wiliam ���������������������������������������������������P2087 Lorent, Joseph H. ��������������������������������� P541,P1355 Lorentzen, Esben �������������������������������������������P1827 Lorenzana Carrillo, Maria Areli �������������������������P316 Lorenzo, Damaris N����������������������������� P388, P1302 Lorenzo, Louis Etienne ���������������������������������������P52 Loros, Jennifer J. ����������������������������������������������P362 Lorson, Christian ��������������������������������������������P1525 Losert, Wolfgang �������������������������������������������� P2117 Losick, Richard �����������������������������������������������P1399 Losty, Paul ������������������������������������������������������ P1103 Lotinun, Sutada ����������������������������������������������P2453 Lotti, Roberta ��������������������������������������������������P2403 Lou, Jieqiong ������������������������������������� P1263, P2067 Lou, Yuanmei ����������������������������������������������������P321

Loubéry, Sylvain ���������������������������������������������P1803 Louder, Robert K. ������������������������������������������� P1174 Louie, Maggie C. ����������������������������������������������P279 Louiselle, Daniel ���������������������������������������������P1386 Louka, Panagiota ���������������������������������������������P993 Love, Andrew C. �����������������������������������������������P743 Love, Dona �����������������������������������������������������P2010 Love, Rachal �������������������������������������� P1776,P1777 Low, JianHui �����������������������������������������������������P886 Low, Tricia Y. �����������������������������������������������������P449 Lowe, Martin ���������������������������������������������������P1265 Löwe, Jan ���������������������������������������������������������P795 Lower, Casey A. �����������������������������������������������P189 Lowery, Laura Anne ���������� P137,P138,P141, P1808 Low-Nam, Shalini ����������������������������������P389,P1157 Loy, Michael M.T. ��������������������������������������������P1296 Lu, Hang ����������������������������������������������������������� P114 Lu, Henry ����������������������������������������������������������P933 Lu, Lei �������������������������������������������������������������P1829 Lu, Li-Fan �������������������������������������������������������P1462 Lu, Long Q. �����������������������������������������������������P1213 Lu, Min-Qi ���������������������������������������������������������P909 Lu, Quanlong ��������������������������������������������������P1827 Lu, Shao-Ying �����������������������������������������������������P40 Lu, Sharon Y. ���������������������������������������������������� P114 Lu, Shuang �������������������������������������������������������P893 Lu, Wen ����������������������������������������������������������P1760 Lu, Ya-Wen �����������������������������������������������������P2164 Lu, Yi-Jhu ������������������������������������������������������� P1104 Lucaj, Christopher ��������������������������������������������P138 Lucarelli, Stefanie ��������������������������������� P395,P2210 Lucas, Alfredo �������������������������������������������������P1702 Lucas, Christine A. �������������������������������������������P906 Lucas, Jessica R. ���������������������������������������������P835 Lucast, Louise ��������������������������������������������������P538 Luchessi, Augusto D. ��������������������������������������P1376 Lucic, Vladan ����������������������������������������������������P400 Lučić, Iva ��������������������������������������������������������P1406 Lucocq, John M. �������������������������������������������������P34 Luders, Jens ������������������������������������������� P970,P975 Ludington, Will B. �������������������������������������������P2421 Ludtke, James J. ����������������������������������������������P864 Ludwig, Alexander ������������������������������������������P1600 Luedke, Kory ����������������������������������������������������P621 Luger, Karolin �������������������������������������������������P1056 Lui, WingYee ��������������������������������������������������P2276 Luisi, Julie ��������������������������������������������������������� P117 Lukac, David ���������������������������������������������������P1603 Łuksza, Małgorzata ������������������������������������������P228 Lundberg, Emma .........��������P503,P507,P508,P623, �����P859,P1034,P1128,P1227,P1540,P1675,P1683, �������������������������� P1684,P1706,P1782,P2092,P2165 Luo, Kathy Qian ���������������������������������������������� P1110 Luo, Tianzhi ������������������������������������������������������P962 Luo, Yibo ��������������������������������������������������������P1026 Lupashin, Vladimir V. ����������������� P420,P1289,P2061 Lusis, Aldons ��������������������������������������������������P2392 Lusk, Patrick ����������������������������������������P1208,P1211 Lusk, Sarah ������������������������������������������������������ P113 Luther, Jamie L. ������������������������������������������������P731 Luthold, Carole �������������������������������������������������P693 Lutz, Mirjam ����������������������������������������������������P1785 Luvsanjav, Delgermaa ������������������������������������P2357 Lux, Samantha �������������������������������������������������P393 Luxton, G.W.Gant �������������������������� P377,P602,P603 Ly, Tony ����������������������������������������������� P1029,P1676 Lynch, Eric M. ���������������������������������������������������P803 Lyon, Andrew S. �����������������������������������������������P972 Lyon, Kevin �����������������������������������������������������P2274 Lyon, Robert C. ����������������������������������������������P2266 Lyons, David A. �����������������������������������������������P1317 Lyons, Samanthe M. �����������������������������������������P305 Lytvyn, Dmytro I. ���������������������������������������������P2322 Lyubchik, Anna �������������������������������������������������P324

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Ma, Catherine �������������������������� P1099,P1101,P2160 Ma, Cheng-I J. ��������������������������������������������������P509 Ma, Hanhui �����������������������������������������������������P1989 Ma, Jianjie ��������������������������������������������������������P189 Ma, Joyce ���������������������������������������������������������P847 Ma, Mary �����������������������������������������������������������P890 Ma, Pengcheng ����������������������������������������������P2376

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Ma, Shibin ������������������������������������������������������P2416 Ma, Tao �������������������������������������������������������������P898 Ma, Tianji ��������������������������������������������������������P1285 Ma, Xiao �����������������������������������������������������������P719 Ma, Xuefei ���������������������������������� P945,P949, P1578 Maas, Richard ������������������������������������������������P2137 Maayan, Inbal �����������������������������������������������������P67 Macara, Ian G. ����������������������������� P457,P458,P1973 MacCoss, Michael J. ������������������ P971, P972,P1897 MacDonald, Chris ���������������������������������������������P405 Macdonald, Dawn ���������������������������������������������P272 MacDonald, Julie A. ������������������������������������������P669 MacDonald, Patrick ����������������������������������������P1332 Macdonald, Susan G. �������������������������������������P2462 Mace, Emily M. ����������������������������������������� P96,P916 Macedo, Aline �������������������������������������������������P2468 MacEwan, Matthew ����������������������������������������P1583 MacFarlane, Alex ��������������������������������������������P1272 Machado, Pedro ���������������������������������������������P2024 Machamer, Carolyn E. �������������������������� P417,P1396 Machesky, Laura M. ���������������������������������������P1720 Machner, Matthias ������������������������������������������P2425 Mackay, Gillian ����������������������������������������������� P1147 MacKay, Joanna L. �����������������������������������������P1951 Macklin, Derek ����������������������������������������������������P67 Macklin, Paul ����������������������������������������������������P285 Macklin, Wendy B. ������������������������������������������P2378 Macleod, Ian �����������������������������������������������������P743 MacTaggart, Brittany ����������������������������������������P945 Madan, Rashna ����������������������������������������������P1368 Maddox, Amy S. ����������������������������������� P743,P1850 Maddox, Paul S. ���� P47,P247,P2350, P1552,P1850 Madey, Alexander G. ��������������������������������������P1704 Madriaga, Antonett �����������������������������������������P1916 Madrid, Rodolfo ����������������������������������������������P1309 Madugula, Viswanadh ������������������������������������P1829 Maehara, Yoshihiko ����������������������������������������P1018 Maeshima, Kazuhiro ���������������������������������������P1996 Magalhaes, Yuli T. ������������������������������������������P2176 Magalon, Karine ���������������������������������������������P2451 Mageswaran, Shrawan K. ����������������������������������P30 Maghelli, Nicola ����������������������������������������������P1550 Magiera, Maria M. ������������������������������������������P1785 Magliocca, Joeseph ����������������������������������������P1597 Magnan, Laure ���������������������������������������������������P95 Mahamid, Julia �������������������������������������������������P967 Mahapatra, Samiksha ������������������������������������P2372 Maharana, Shovamayee ����������������������������������P700 Mahdessian, Diana P507,P508,P623,P1034,P1684, ������������������������������������������������������������������������P1782 Mahjoub, Moe R. ������������������������ P155, P368,P1826 Mahmud, Hafizah B. ���������������������������������������P1946 Mahon, Aoife ��������������������������������������������������P1660 Mahserejian, Shant M. �����������������������������������P1812 Mai, Yosuke ������������������������������������������������������P680 Maiato, Helder J. ��������������������������������� P1060, P218 Maihle, Nita J. ������������������������������������� P1941,P1969 Maillard, Rodrigo A. ���������������������������� P2186,P2339 Maillet, Marjorie ������������������������������������������������P424 Maimouni, Sara ���������������������������������������������� P1131 Maitland, Norman J. ���������������������������������������P1098 Maitre, Marlène ����������������������������������������������P1486 Maity, Debonil �������������������������������������������������P1496 Maiuri, Paolo ���������������������������������������P1154,P1756 Maiuri, Tam ������������������������������������������� P880,P2457 Maizy, Yousif �����������������������������������������������������P163 Majd, Sheereen ������������������������������������������������P120 Majesky, Mark W. �������������������������������������������P2481 Maji, Samir K. ������������������������������������������������� P1115 Majkut, Stephanie ���������������������������������������������P600 Majolee, Jisca �������������������������������������������������P1454 Major, Ben ��������������������������������������������������������P480 Major, Jennifer L. ���������������������������������� P686,P2475 Majstrowicz, Katarzyna ������������������������������������P947 Majumdar, Shreoshi ���������������������������������������P1790 Majumdar, Sunipa �����������P897,P1948, P898,P1972 Makalinao, Andrew �����������������������������������������P2314 Makaraci, Pelin ����������������������������������� P1291,P2057 Maker, Allison ���������������������������������������������������P803 Makhanov, Mikhail ������������������� P1173,P2440,P2458 Makushok, Tatyana �����������������������������������������P2109 Malaquin, Laurent ���������������������������������������������P875 Maldonado, Geronimo ������������������������ P1974,P1975 Maldonado-Baez, Lymarie ������������������������������P1268

Malfatti, Michael �����������������������������������������������P277 Malhotra, Aditi �������������������������������������������������P1269 Malhotra, Vivek �������������������������������������������������P416 Malicdan, MayChristine V. ������������������������������P1281 Malik, Anna R. ��������������������������������������������������P475 Malik, Asrar B. ������������������������������������ P1474,P1491 Malik, Sana S. ������������������������������������������������P1538 Malinowska, Agata �����������������������������������������P1954 Malinsky, Jan ����������������������������������������������������P357 Maliszewska, Kamila ��������������������������������������P1954 Maller, Ori ������������������������������������������������������� P1158 Maltsev, Natalia ������������������������������������������������P670 Maly, Ivan V. �����������������������������������������������������P340 Mamchaoui, Kamel �������������������������������������������P988 Mamede, Joao I. �������������������������������������������������P30 Mamiya, Atsushi ����������������������������������� P682,P1655 Mana-Capelli, Sebastian ��������������������������������P1472 Manandhar, Surya P. ��������������������������������������P2080 Mañas, Adriana ���������������������������������������� P74,P670 Mâncio, Rafael D. �������������������������������������������P2470 Mandal, Kalpana ����������������������������������������������P382 Mandigo, Torrey R. ������������������������������ P372, P2465 Mandujano-Ramos, Ivan A. ����������������������������P2040 Manel, Nicolas ��������������������������������������������������P376 Manfiolli, Adriana O. ���������������������������������������P1401 Mangan, Anthony J. ����������������������������������������P2104 Mangeat, Thomas �������������������������������������������P1455 Mangenot, Stephanie �������������������������������������P1444 Manil-Segalen, Marion �������������������������������������P228 Manley, Nancy R. �����������������������������������������������P64 Mann, Barbara ������������������������������������ P1881,P1891 Mann, Thomas H. ��������������������������������� P595,P2184 Mannard, Erin ���������������������������������������������������P439 Mannheimer, Joshua ����������������������������������������P305 Mannowetz, Nadja ������������������������������������������P1008 Mansell, Steven A. ������������������������������������������P1008 Mantus, Grace E. �������������������������������������������P2066 Manzo-Merino, Joaquin ����������������������������������P1244 Mao, Bingyu ���������������������������������������������������P2376 Mao, Suifang ����������������������������������������������������P147 Mao, Yingwei ��������������������������������������������������P2393 Mao, Zhiyong ��������������������������������������������������P2305 Marceau, Caleb D. �������������������������������������������P559 Marcey, David J. �������������������������������������������������P20 March, Joe L. 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�������������������������P1171, P587 Markley, Rachel L. ����������������������������� P1640, P2418 Marks, Michael S. ��������������������������������� P499,P1276 Marks, Rebecca �����������������������������������������������P290 Markus, Barak ��������������������������������������������������P370 Markus, Steven M. ����������������������������� P1772,P1895 Marquina, Javier �������������������������������������������������P44 Marr, Kendra ��������������������������������������������������� P2119 Marr, Linsey ������������������������������������������������������P190 Marrot, Laurent �����������������������������������������������P2302 Marsboom, Glenn �������������������������������������������P2390 Marsh, Timothy ����������������������� P2077,P2324, P2333 Marshall, Owen J. �������������������������������������������P2386 Marshall, Wallace F. .................P766,P1011, P1395, ������������������������������������������������������������ P1892,P2109 Marthiens, Veronique ����������������������������� P155,P228 Martin, Adam �������������������������������������� P1890,P2359 Martin, Allison ���������������������������������������������������P839 Martin, Maud ��������������������������������������������������P2358 Martin, Patrick M. ����������������������������������������������P269 Martin, Sophie G. ������������������������������� P2100,P2101 Martinelli, Valerie ����������������������������������������������P371 Martinez, Eduardo ��������������������������������������������P290 Martinez, Fernando A. ��������������� P514,P1007,P2114 Martinez, Gabriela ��������������������������������������������P580

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Martinez, Lisa M. ������������������������������������ P60,P2444 Martinez, Marcia ���������������������������������������������P2434 Martinez, Pablo ����������������������������������������������P1366 Martinez-Calejman, Camila ����������������������������P1375 Martinez-Guzman, Dee Ann ���������������������������P1618 Martinez-Marquez, Jorge Y. �������������������� P408,P423 Martinez-Montemayor, Michelle M. ...... P276,P1923, ..................................................P1949,P1974,P1975 Martinez-Rivera, Noraida �����������������������������������P29 Martinez-Rodriguez, Luis E. ���������������������������P1521 Martinka, Scott A. �������������������������������������������P2208 Martins, Isabelle ��������������������������������������������� P1153 Martins, Mauricio R. �����������������������������������������P484 Martins, Nuno ���������������������������������������������������P371 Marttinen, Paula ���������������������������������������������P1333 Martuscello, Regina T. ������������������������������������P1951 Maruthamuthu, Venkat �����������������������������������P1461 Maruyama, Mitsuki �����������������������������������������P1694 Marwaha, Rituraj �������������������������������� P1254,P2076 Masannat, Jude ����������������������������������������������P1983 Maschio, Daniela A. ������������������������������������������P562 MasGomez, Nestor ������������������������������������������ P511 Mashukova, Anastasia �������������������������������������P456 Masiello, Timothy ����������������������������������������������P341 Maslakova, Aitsana A. ������������������������������������ P1169 Maso, Victor ������������������������������������������������������P265 Mason, Frank M. ��������������������������������������������P2359 Mass, Elvira ������������������������������������������������������P789 Massimi, Paola ��������������P465,P1126,P1244, P1604 Mastronardi, Karina ������������������������������������������P769 Matak, Damian �����������������������������������������������P1954 Mateju, Daniel ��������������������������������������������������P700 Mateos-Langerak, Julio ����������������������������������P2248 Matera, A. G. ��������������������������������������������������P1525 Materassi, Donatello �����������������������������������������P125 Mathavan, Ketan ��������������������������������������������P1560 Matheson, Timothy D. ������������������������������������P1986 Matheus, Valquiria A. ����������������������������������������P636 Mathew, Joseph K. ������������������������ P646,P937,P939 Mathiowetz, Alyssa J. ���������������������������������������P935 Mathur, Aastha �����������������������������������������������P1448 Mathur, Vinayak ������������������������������������������������P831 Matsuda, Miho ������������������������������������������������P1590 Matsudaira, Paul T. �������������������������������������������P721 Matsui, Hirofumi ���������������������������������������������P1934 Matsui, Tohru ��������������������������������������������������P1642 Matsui, Yurika ���������������������������������������������������P561 Matsumoto, Erino ���������������������������������������������P876 Matsumoto, Hiroyuki �����������������������������������������P871 Matsumura, Kengo �������������������������������������������P261 Matsuura, Akira ���������������������������������� P2312,P2313 Mattis, Virginia ��������������������������������������������������P880 Mattison, Christopher P. ���������������������������������P1379 Mattson-Hoss, Michelle ����������������������������������P1753 Matus, David Q. ������������������������������������ P784,P1970 Maurin, Mathieu ����������������������������������������������P2219 Mauro, Ava J. ��������������������������������������������������P1812 Mavrakis, Manos ���������������������� P915,P1444, P1456 Maxfield, Frederick R. ������������������������������ P94,P579 Maxson, Julia ���������������������������������������������������P574 Maxwell, Christopher A. ����������� P1025,P1151,P2113 May, Caitlin �������������������������������������������������������P834 May, Christopher ��������������������������������������������P1219 Mayer, Ghislaine ��������������������������������� P1607,P1608 Mayeux, Adeline ���������������������������������������������P1073 Mayeux, Philip ������������������������������������������������P2202 Mayor, Satyajit .....................P646,P930,P931,P937, ����������������������������������������P939,P1356,P1569,P2201 Mayor, Thibault ������������������������������������������������� P711 Mazaharul, Islam ��������������������������������������������P1588 Mazaki, Yuichi ���������������������������������������������������P680 Mazhar, Adli ����������������������������������������������������P1992 Mazo, Greg �����������������������������������������������������P1027 Mazroui, Rachid ��������������������������������������������� P1194 Mazza, Davide ������������������������������������������������P1668 Mazzafferri, Javier ����������������������������������������������P52 McAinsh, Andrew D. ���������������������������������������P1080 McBeath, Elena ������������������������������������������������P869 McBride, Trevor J. ��������������������������������������������P690 McCall, Patrick M. ���������������������������������������������P104 McCann, Richard O. �����������������������������������������P654 McCarty, Owen �����������������������������������������������P1365 McCaslin, Darrell R. ����������������������������������������P1379 McClain, Melainia ���������������������������������������������P365

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AUTHOR INDEX Mcclatchey, Penn M. ����������������������������������������P671 McClellan, Mark ������������������������������������������������P142 McClelland, Erin E. �����������������������������������������P2417 McClelland, Sarah E. ����������������������������������������P229 McCloskey, Asako ������������������������������������������P1218 McColl, James ������������������������������������������������P2193 McCollum, Dannel ������������������������������������������P1472 McCormick, Kathryn E. �����������������������������������P2464 McCormick, Laura E. ������������������������������������������P89 McCormick, Peter �������������������������������������������P1286 McCreedy, Evan �������������������������������������������������P44 McCubbin, Seth M. �������������������������������������������P132 McCulloch, Christopher A. ��������������������������������P652 McCusker, Derek W. �����������������������������������������P448 Mcdaniel, Kelly �������������������������������������������������P344 McDermott, Hyoeun ���������������������������������������P2057 McDonald, Jocelyn A. �������������������������������������P1433 McDonald, Kelly �����������������������������������������������P839 McDonald, Kent L. ������������������������������ P1215,P1344 McDonald, Nathan A. �������������������������������������P1843 McDonald, Paul C. �������������������������������������������P321 McDonald, Seth ������������������������������������������������P384 McDonough, Liam ��������������������������������������������P709 McDougall, Alex ������������������������������������������������P172 McDowell, Colleen M. �������������������������������������P1498 McDowell, Gary S. ��������������������������������������������P828 McElderry, Brenna ��������������������������������������������P757 McEnroe, Tony ������������������������������������������������P1660 Mcfadden, William M. ���������������������������������������P109 McFarlane, Renee ����������������������������������������������P22 McField, Brianna ��������������������������������������������P2086 McGee, Erin L. �����������������������������������������������P2263 McGee, Richard �����������������������������������������������P848 McGehee, James �������������������������������������������P1869 McGrath, Jamis K. ��������������������������������������������P108 McGraw, Timothy E. ����������������������������� P419,P2213 McGriff, Sarah ������������������������������������������������P1562 McGuinness, Jennifer R. ����������������������������������P229 McInally, Shane G. �����������������������������������������P1818 McIntosh, J. R. �����������������������������������������������P1020 McIntyre, Jeremy C. �����������������������������������������P154 McKay, Tina ����������������������������������������������������P1495 Mckenna, Aaron ���������������������������������������������P2481 McKenney, Richard J. ������������������������� P1767,P1898 McKim, Kim S. ������������������������������������������������P1872 McKinney, Sean ����������������������� P2119,P2389,P2420 McKinzie, Jamie �������������������������������������������������P97 McKnight, Steven L. �����������������������������������������P625 McKown, Elizabeth N. ������������������������������������P2294 McLachlan, Ian G. ������������������������������������������P1473 McLamarrah, Tiffany A. ������������������������� P206,P1070 McLaughlin, Tyler �����������������������������������������������P96 Mclaurin, Justin D. ��������������������������������������������P741 McMahon, Lloyd ���������������������������������������������P1247 McMahon, Moira �����������������������������������������������P203 McMorrow, Tara ������������������������������������������������P158 McNally, Francis J. ������������������ P1876,P1903,P1905 McNally, James G. ������������������������������������������P1668 McNally, Karen ����������������������������������� P1903,P1905 McNamara, William ������������������������������������������P324 McNeely, Katrina C. ����������������������� P174,P177,P476 McNiven, Mark A. ����������������������������������� P309,P435 McNulty, Shannon M. �������������������������������������P2015 McPherson, Peter S. ���������������������������� P439,P1259 McQueen, Jennifer �������������������������������������������P553 McQuilken, Molly ��������������������������������������������P1669 McRae, Andrea S. ������������������������������������������P1838 McSweeney, Colleen ��������������������������������������P2393 McTigue, Monica M. ���������������������������������������P1503 McVicker, Derrick P. ������������������������������������������P489 McWilliams-Koeppen, Penney �������������������������P877 Md Thoufic Anam, Azad ����������������������������������P2450 Measday, Vivien �����������������������������������������������P553 Mechulam, Yves ���������������������������������������������P1979 Medeiros, Ana C. ��������������������������������������������P1401 Medeiros, Audrey T. ������������������������������������������P398 Medema, Rene H. �������������������������������� P200,P1040 Medh, Rheem D. ��������������������������������P1106, P1120 Medina-Lopez,B.S., Aidyn M. �����������������������������P29 Medina-Pritchard, Bethan �������������������������������P1066 Meednu, Nida �������������������������������������������������P1788 Mege, Rene-Marc �������������������������������������������P1471 Mehra, Surabhi ����������������������������������������������� P1115 Mehta, Aakash ��������������������������������������������������P696

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Mehta, Guneet ��������������������������������������������������P847 Mehta, Gunjan D. �������������������������������������������P1668 Mehta, Parmender P. ����������������������������������������P630 Mehta, Shalin ���������������������������������������������������P646 Mehta, Shalin B. ���������������������������������������������P1669 Mehta, Varun ����������������������������������������������������P298 Meinecke, Michael ��������������������������������������������P521 Meiners, Jens C. ��������������������������������������������P1226 Meiring, Joyce ��������������������������������������������������P905 Meister, Thomas R. ������������������������������������������P414 Meitinger, Franz ����������������������������������������������P1038 Melchor, George S. ���������������������������������������� P1118 Melendez, Alicia �����������������������������������������������P436 Mellinghoff, Ingo K. �������������������������������������������P288 Mello, Helena �������������������������������������������������P1603 Meluch, Beata ������������������������������������������������P1673 Melunis, Justin ����������������������������������������������������P48 Melville, David B. ����������������������������������������������P431 Melvin, Paul ��������������������������������������������������������P22 Memarzadeh, Kimiya ��������������������������������������P1257 Memili, Erdogan ���������������������������������������������P2012 Menchen, Tabea �����������������������������������������������P152 Mendes, Adelia �������������������������������������������������P371 Mendes, BernardoJorge d. �����������������������������P2293 Mendez, Aaron S. �������������������������������������������P1509 Meneguello, Letícia ����������������������������������������P1376 Menezes, Erika �����������������������������������������������P2012 Meng, Fanrui �������������������������������������� P1661,P2244 Meng, Fanyin ��������������������������������������� P344, P1651 Meng, Qinggang �����������������������������������������������P345 Menking-Hoggatt, Maya N. �����������������������������P2405 Menon, Mary K. ����������������������������������������������P1916 Menon, Shalini ���������������������������� P480,P2054, P892 Mensa-Wilmot, Kojo A. �����������������������������������P1609 Mera-Jiménez, Elvia ���������������������������������������P2452 Mercado-Perez, Arnaldo ���������������������������������P2357 Merck, Georg ����������������������������������������������������P126 Merdes, Andreas ����������������������������������������������P968 Merical, Matthew S. ������������������������������������������P573 Merkel, Chelsea D. ����������������������������� P1469,P1481 Merlini, Laura ��������������������������������������������������P2101 Merrill, Charlotte L. �����������������������������������������P2238 Merryman, Shane �������������������������������������������P2420 Mershon, Blaine �����������������������������������������������P534 Merz, Alexey J. �������������������������������������������������P540 Mesner, Peter W. ����������������������������������������������P685 Messa, Mirko �������������������������������������������� P55,P535 Messelaar, Emily M. �����������������������������������������P941 Messenberg, Anat ��������������������������������������������P649 Messina, Abbey ����������������������������������������������P1960 Mettlen, Marcel �������������������������������������������������P394 Meyen, Dana ��������������������������������������������������P2363 Meyer, Tobias ������������������������������������� P1049,P1429 Meyers, Stuart ������������������������������������������������P1008 Mezzache, Sakina ������������������������������������������P2302 Mezzano, Valeria ��������������������������������������������P2266 MHU Turabe, Fazil �������������������������������������������P886 Miao, Yong ������������������������������������������������������P1358 Michael, Nick ����������������������������������������������������P976 Michalaki, Eleftheria ���������������������������������������P2254 Michelot, Alphée ���������������������������������������������P1710 Mickolajczyk, Keith J. �������������������������������������P1761 Middleton, Kim ������������������������������������ P1367,P1680 Midura, Devin �������������������������������������������������P1582 Mierzwa, Beata �����������������������������������������������P2094 Mietke, Alexander �������������������������������������������P2365 Miga, Karen H. �������������������������������������������������P203 Mihelc, Elaine M. ��������������������������������������������P1601 Mikawa, Takashi ���������������������������������������������P2354 Milan, Jean-Louis �������������������������������������������P2216 Milas, Ana ���������������������������������������������������������P186 Milberg, Oleg ��������������������������������������������������P1452 Milenkovic, Ljiljana �����������������������������������������P2148 Miletti-Gonzalez, Karl E. ���������������������������������P1966 Milev, Miroslav P. ����������������������������������������������P412 Milhiet, Pierreemmanuel ���������������������������������P1444 Millan, Ivan �������������������������������������������������������P983 Millar, Cameron ����������������������������������������������P1498 Millen, Kathleen ����������������������������������������������P2481 Miller, Ann L. ����������� P465,P635,P640,P2270,P2367 Miller, Elizabeth A. ������������������������������������������P2422 Miller, Eric W. ������������������������������������������������������P91 Miller, Evan R. ����������������������������������� P1361, P2388 Miller, John H. �������������������������������������������������P1787

Miller, Kelly �����������������������������������������������������P1017 Miller, Kristi E. ���������������������������������������������������P468 Miller, Martin ���������������������������������������������������P1074 Miller, Melissa R. ��������������������������������� P756, P1008 Miller, Rachel A. ������������������������������������ P731,P1704 Miller, Rita K. ��������������������������������������������������P1788 Miller, Sonni-Ali �����������������������������������������������P2434 Miller, Zane �������������������������������������������������������P812 MillerIII, David M. ��������������������������������������������P2124 Miller-Jensen, Kathryn ��������������������������������������P558 Millis, Bryan A. ������������������������������������������������P1859 Mills-Henry, Ishara A. ��������������������������������������P1682 Mimaki, Yoshihiro ���������������������������������������������P270 Min, Li ���������������������������������������������������������������P882 Minakawa, Noriaki ������������������������������������������ P1196 Minami, Itsunari ����������������������������������������������P2392 Minatel, Elaine ������������������������������������ P2468,P2470 Minc, Nicolas ������������������P445,P1858,P2098,P2115 Minegishi, Takunori �������������������������������������������P482 Miner, Gregory ������������������������������������������������P1278 MinguetSànchez, Marta �����������������������������������P560 Minoda, Aki �����������������������������������������������������P2008 Minshall, Richard D. ���������������������������������������P1377 Miraoui, Hichem ���������������������������������������������P2137 Mirny, Leonid ��������������������������������������������������P1990 Mironov, Aleksandr �����������������������������������������P1265 Mirrashidi, Kathleen ���������������������������������������� P2411 Mirza, Amar ����������������������������������������������������P1373 Mirza, Anne M. �����������������������������������������������P2051 Mirzaei, Hamed ������������������������������������������������P878 Miserey-Lenkei, Stephanie �����������������������������P1287 Miserey-Lenkei, Stephanie ����������������� P1288,P1447 Mishra, Gargi ����������������������������������������������������P789 Mishra, Mithilesh ��������������������������������������������P1851 Misteli, Tom �����������������������������������������������������P1217 Mitchell, Amir �������������������������������������������������� P1122 Mitchell, Claire H. ��������������������������������������������� P511 Mitchell, Danae �����������������������������������������������P1797 Mitchell, David R. �������������������������������������������P1010 Mitchell, Diana ��������������������������������������������������P179 Mitchison, Timothy J. ����������������������������������������P169 Mithun, Mitra ��������������������������������������������������� P1190 Mitra, Pallabi ��������������������������������������������������� P1197 Mitsui, Toshiyuki ���������������������������������������������P1692 Mittag, Sonnhild ����������������������������������������������P2271 Miwa, Soichi �����������������������������������������������������P680 Miyagi, Mari ����������������������������������������������������P2291 Miyamoto, Eri �������������������������������������������������P2079 Miyamoto, Yuko J. ������������������������������������������P1391 Miyano, Masaru ����������������������������������������������P2300 Miyano, Rie ����������������������������������������������������P1360 Miyashita, Naoyuki �������������������������������������������P874 Miyawaki, Yoshiko ������������������������������������������ P1107 Mizobuti, Daniela S. ���������������������������������������P2468 Mizokami, Akiko ����������������������������������������������P2191 Mizuno, Kensaku ���������������������������������� P610,P1821 Mizuno, Tomoaki �����������������������������������������������P641 Mizushima, Noboru ����������������������������������������P2074 Mizuuchi, Kiyoshi ���������������������������������� P797,P1539 Mizzen, Craig A. ���������������������������������������������P2018 Mladenov, Miroslav �����������������������������������������P1774 Mlodzik, Marek �������������������������� P776,P1571,P2112 Mlynarczyk, Paul ��������������������������������������������P1849 Mo, Fei �������������������������������������������������������������P195 Mo, Xuming ����������������������������������������������������P1578 Moalim, Abdiwahab Y. �������������������������� P620,P2242 Möbius, Wiebke ������������������������������������������������P521 Modica, Graziana ���������������������������������������������P433 Mody, Avani A. ������������������������������������������������P2447 Modzelewski, Andrew J. �����������������������������������P756 Moe, Alison �����������������������������������������������������P2177 Moe, Christina ������������������������������������������������P2262 Moehlman, Andrew T. �������������������������������������P1506 Moeller, Jens ��������������������������������������������������P1695 Moenk, Michael ���������������������������������������������� P1172 Moens, Cecilia B. ��������������������������������� P326,P2369 Moerman, Donald ���������������������������������������������P746 Moerner, William E. ��������P595,P1663,P1672,P2148 Moffatt, Christopher A. ��������������������������������������P494 Moffitt, Jeffrey R. ��������������������������������������������P1991 Mofrad, Mohammad �...........P377,P486,P602,P603, ...............P1690,P2032,P2033,P2034,P2044,P2045, .......................................P2046,P2228,P2230,P2288 Mogensen, Johanne B. ����������������������������������P1839

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Mogessie, Binyam ������������������������������������������P1030 Mohamed, Attia I. �������������������� P1340,P2166,P1341 Mohammed, Danahe ��������������������������������������P2260 Mohammed, Hali ��������������������������������������������P1441 Mohan, Krithika ������������������������������������������������P962 Mohan, Pooja ������������������������������������������������� P1151 Mohan, Ryan D. ���������������������������������������������P2389 Mohler, William ���������������������������������������������������P44 Mohr, Jordan D. ����������������������������������������������P1409 Mojiri, Anahita ���������������������������������������������������P316 Mok, Sue Ann ���������������������������������������������������P887 Mokkapati, Animisha �����������������������������P811,P1950 Molina, Oscar �����������������P235,P1066,P1067,P1893 Molinie, Nicolas ��������������������������������������������������P75 Molkentin, Jeffery D. ����������������������������� P424,P1497 Molle, Dorothee ������������������������������������������������P419 Mon, Aye M. ����������������������������������������������������P1426 Monack, Denise ����������������������������������������������P1629 Monda, Julie K. �����������������������������������������������P1780 Mondal, Alok K. ������������������������������������������������P542 Monier, Bruno �������������������������������������������������P1455 Moninger, Thomas ��������������������������������������������P147 Monk, Kelly R. ������������������������� P1317,P1583,P2379 Monkiewicz, Caroline �������������������������������������P2054 Montagut, Carlota ������������������������������������������� P1311 Montecino, Martin �������������������������������������������P1366 Monteiro, Pedro ����������������������������������������������P1080 Montel, Valerie ��������������������������������������������������P890 Montembault, Emilie ����������������������������� P198,P1856 Montgomery, McKale R. �������������������� P1920, P2263 Monti, Stefano ������������������������������������������������P1566 Montibus, Bertille ������������������������������������������������P95 Montico, Fabio ������������������������������������������������P2308 Moon, HyoYoul ����������������������������������������������� P1129 Moon, Kyung-Mee ������������������������������������������P2244 Mooney, David J. ��������������������������������������������P1487 Moonyham, Ashley �������������������������������������������P142 Moore, Emily R. ������������������������������������������������P149 Moore, Jeffrey K. P131,P1775,P1796,P1797,P1813 Moore, Quincy ����������������������������������������������������P28 Moore, Steven ��������������������������������������������������P412 Moore, Travis I. �������������������������������������������������P646 Mooseker, Mark S. �����������������������������������������P1742 Mootha, Vamsi K. �������������������������������������������P1346 Mopas, Joshua �������������������������������������������������P890 Morales, Carlos R. ������������������������������������ P41,P501 Morales, Diego �����������������������������������������������P1437 Morar, Vikash ��������������������������������������������������P1324 Moreau, Violaine ������������������������������������� P95,P1486 Moreau-Toussaint, Valerie ��������������������������������P865 Morein, Justin J. �����������������������������������������������P439 Morel, Anne ����������������������������������������������������P2248 Morell, Montse ��������������������������������������������������P871 Moreno, Belen ������������������������������������������������P2099 Moreno-Andrés, Daniel ����������������������������������P1801 Morfini, Gerardo ���������������������������������������������P1320 Morgan, Alejandra ������������������������������ P1437,P2307 Morgan, Jennifer R. �������������������������������� P398,P399 Morgan, Julie E. �������������������������������������������������P22 Morgan, Marc �������������������������������������������������P1963 Morganthaler, Alisha N. ���������������������������� P84,P895 Morgen, Jeanette J. ������������������������������������������P642 Morgens, David W. �������������������������������������������P164 Mori, Eiichiro �����������������������������������������������������P625 Mori, Koko ������������������������������������������������������P2336 Mori, Masahiro ��������������������������������������������������P826 Mori, Masashi �������������������������������������������������P2024 Mori, Toshiaki ����������������������������������������������������P725 Mori, Yasuo �����������������������������������������������������P1044 Morikawa, Manatsu �������������������������������P114,P1750 Morimatsu, Masatoshi �������������������������� P614,P2237 Morin, Genevieve ���������������������������������������������P972 Morinaga, Takao �����������������������������������������������P409 Morisaki, Tatsuya ��������������������������������������������P1668 Morita, Mistake �����������������������������������������������P2338 Moritz, Michelle �������������������������������������� P971,P972 Moriuchi, Masataka ����������������������������������������P2338 Moriwaki, Takashi ���������������������������������������������P135 Moriya, Misaki ���������������������������������������������������P857 Morley, Celeste �������������������������������������������������P898 Morozov, Viacheslav M. ����������������������������������P2006 Morrell-Falvey, Jennifer L. ��������������������������������P264 Morrice, Nick ��������������������������������������������������� P1147 Morris, Caitlin ����������������������������������������������������P440

Morris, John F. ��������������������������������������������������P339 Morris, Michael J. �������������������������������������������P1688 Morris, Savannah �������������������������������������������P1788 Morrison, Deborah ������������������������������������������P1827 Morrissey, Meghan A. ������������������������� P2168,P2204 Morsci, Natalia S. ���������������������������������������������P992 Morselli, Marco �����������������������������������������������P2392 Mortensen, Kim I. �������������������������������� P961, P1665 Mortensen, Marie L. ���������������������������������������P1915 Mortensen, Richard D. ������������������������� P779,P2368 Morthorst, Stine K. ������������������������������������������P1839 Morton, Leslie A. ���������������������������������������������P2150 Mosalaganti, Shyamal ������������������������������������P1657 Moseley, James B. �������������������� P594,P1393,P1403 MoservonFilseck, Joachim �����������������������������P2094 Moss, Diana ���������������������������������������P1103, P1148 Mostowy, Serge ����������������������������������������������P1599 Motadi, Lesetja R. ������������������������������������������ P1117 Motegi, Fumio ���������������������������������������������������P449 Mothes, Walther �����������������������������������������������P558 Motlik, Jan ������������������������������������������������������P1998 Motohashi, Reika ����������������������������������������������P826 Moufarrej, Mira N. ������������������������������������������� P1163 Moulick, Roumita ����������������������������������������������P701 Moulis, Manon ������������������������������������������������P2451 Mound, Abdallah ���������������������������������������������P1354 Moura, Arlindo ������������������������������������������������P2012 Mouri, Kazunari ������������������������������������������������P577 Mousavi, Sayed I. ���������������������������������������������P728 Moussavi-Baygi, Ruhollah ������� P2044,P2045,P2046 Moutel, Sandrine ����������������������������������������������P866 Mouzakis, Kathryn D. ���������������������������������������P351 Moyle, Mark ����������������������������������������������������P1902 Mücahit, Huri Ü. ����������������������������������������������P1727 Mudianto, Tenny ���������������������������������������������P2197 Mudumbi, Krishna C. ��������������������������������������P2029 Mueller, David M. ��������������������������������������������P1822 Mueller, Florian �����������������������������������������������P1668 Mueller, Irina A. �����������������������������������������������P1326 Mueller, Joachim D. ������������������������������������������P377 Mueller, Lauren �����������������������������������������������P2172 Muenster, Stefan ��������������������������������������������P2365 Muesch, Anne �������������������������������������������������P1295 Muhamed, Ismaeel �����������������������������������������P1476 Muhire Gihana, Gabriel ����������������������������������P1048 Muinonen-Martin, Andrew ������������������������������ P1147 Mukherjee, Richik Nilay ������������������������������������P505 Mukherjee, Soumya ������������������������������� P196,P244 Mukhopadhyay, Saikat �����������������������������������P1828 Mukoyama, Yosuke ������������������������������������������P949 Mulholland, Christopher B. �����������������������������P2016 Mullen, Timothy J. ������������������������������������������P1032 Muller, Eric �������������������������������������������� P972,P1879 Muller, Marc ���������������������������������������������������� P1181 Müller, Jan M. �����������������������������������������������������P85 Müller-Planitz, Felix ������������������������������������������P963 Müller-Reichert, Thomas .............P240,P255,P1022, ............................................................. P1888,P2094 Mulligan, Lois M. �������������������������������������������� P1121 Mullins, R. D. ���������������������������������������� P796,P1735 Mun, Kevin �����������������������������������������������������P2286 Munakata, Miyo ����������������������������������������������P1559 Munari, Mika �������������������������������������������������������P49 Muncie, Jonathon M. ��������������������������������������P2373 Mund, Markus ���������������������������������������������������P391 Mund, Thomas ������������������������������������������������P1534 Munlyn, Ambra L. ���������������������������������������������P551 Munneke, Allyson �������������������������������������������P2126 Munoz, Carlos ������������������������������������������������P1702 Munoz, Jonathan ��������������������������������������������P1608 Muñoz, Ana L. ��������������������������������������������������P406 Munro, Edwin M. ������������������������������������ P109,P453 Munro, Sean ���������������������������������������������������P2056 Munsie, Lise N. �����������������������������������������������P1266 Munson, Jennifer �������������������������������������������� P1158 Munson, Mary �������������������������������������������������P2051 Muppala, Santoshi ������������������������������������������P1502 Murakami, Ayako ��������������������������������������������P1590 Murakami, Luc ������������������������������������������������P1909 Murakami, Masaru ������������������������������������������P1642 Murakami, Ryo �������������������������������������������������P857 Muretta, Joseph ����������������������������������������������P1753 Murley, Andrew �������������������������������������������������P550 Murphy, Christopher J. ����������������������� P1502,P2295

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Murphy, James M. �������������������������������� P657,P1404 Murphy, Robert F. �������������������������������������������P1034 Murray, Andrew W. �����������������������������������������P1724 Murray, David H. ���������������������������������������������P2068 Murray, John ����������������������������������������� P989,P1081 Murray, Sandra A. ���������������������������������������������P634 Murrow, Lyndsay M. �����������������������������������������P733 Murugesan, Sricharan ����������������������������������������P87 Muscat, Christina C. ���������������������������������������P1906 Mussakhan, Sultan �����������������������������������������P1087 Musser, Tiffany �����������������������������������������������P1048 Mustafi, Sushmita �������������������������������������������P1627 Mustapha, Mirna ������������������������������������� P950,P959 Muthusamy, Nagendran ���������������������������������P1313 Myer, Nicole M. �������������������������������������������������P136 Myers, Gene ���������������������������������������������������P1550 Myers, Jamie L. ����������������������������������������������P1688 Myers, Kenneth A. ������������������������� P136,P145,P660 Myers, Michael P. �������������������������������P1126, P1604 Myre, Michael �������������������������������������������������P2087

N

Na, Sungsoo �����������������������������������������������������P615 Nabi, Ivan R. �������������������P321,P1661,P2162,P2244 Nachmias, Dikla ���������������������������������������������P1834 Nachury, Maxence V. ������������������������������ P164,P165 Nacke, Marisa ��������������������������������������������������P318 Nader, Helena B. ��������������������������������������������P2226 Naeem, Aisha ���������������������������������������������������P816 Nag, Suman ������������������������������������������ P961, P944 Nagai, Tomoaki �����������������������������������������������P1821 Nagao, Rika ����������������������������������������������������P2291 Nagaoka, Kentaro ��������������������������������������������P753 Nagashima, Haruki �����������������������������������������P2052 Nagata, Aiko ���������������������������������������������������P2152 Nagavarapu, Usha ����������������������������� P2435,P2460 Nagayasu, Eiji ��������������������������������������������������P989 Nager, Andrew R. ���������������������������������������������P165 Nagre, Nagaraja ���������������������������������� P820, P2426 Nagy, James I. ������������������������������������������������P2132 Nagy, Karoly ��������������������������������������������������� P1107 Nagy, Tamas �����������������������������������������������������P881 Naim, Valeria ����������������������������������������������������P204 Nair, Jyoti ��������������������������������������������������������P1562 Nair, Neha ������������������������������������������������������P1946 Nairn, Angus C. ������������������������������������������������ P115 Naito, Akira �����������������������������������������������������P1652 Naito, Tomoki ��������������������������������������������������P1360 Nakada-Tsukui, Kumiko ����������������������������������P2079 Nakagushi, Mikiko ��������������������������������������������P143 Nakajima, Kazunori ����������������������������������������P2344 Nakamura, Akari ���������������������������������������������P2466 Nakamura, Kyotaro ����������������������������������������P2291 Nakamura, Nobuhisa ����������������������������������������P787 Nakamura, Takanori ���������������������������������������P1045 Nakano, Austin �����������������������������������������������P2392 Nakano, Haruko ���������������������������������������������P2392 Nakano, Miwa ���������������������������������������������������P379 Nakano, Tomoyuki ������������������������������������������P1636 Nakano, Toshitake ������������������������������������������P2304 Nakano, Yoshio ����������������������������������������������P2338 Nakano, Yukiko �����������������������������������������������P2120 Nakasone, Alice ����������������������������������������������P1054 Nakata, Susumu �����������������������������������������������P261 Nakatani, Naoki ������������������������������������������������P722 Nakatsuji, Norio ����������������������������������������������P2392 Nakayama, Kazuhisa ������������������������� P1360,P1833 Nakazawa, Eiko ��������������������������������������������������P50 Nakazawa, Naotaka �����������������������������������������P608 Nale, Andrea �����������������������������������������������������P589 Nalepa, Grzegorz ���������������������������������������������P217 Nam, Ki-hwan �������������������������������������������������P2259 Nam, Sungmin ��������������������������������������������������P606 Namgoong, Suk ���������������������������������� P1739,P1740 Nan, Beiyan ������������������������������������������������������P806 Nance, Jeremy �������������������������������������������������P770 Nandadasa, Sumeda ��������������������������������������P1317 Nandi, Nilay ����������������������������������������������������P2321 Nandini, Swaran ���������������������������������������������P1776 Nano, Maddalena ���������������������������������������������P180 Narayanan, Padmini ���������������������������������������P2144 Narayanan, Vani ���������������������������������������������P1465 Narita, Akihiro ������������������������������������ P1671, P1716

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AUTHOR INDEX Naruse, Keiji ����������������������������������������� P614,P2237 Naseri, Ardalan �����������������������������������������������P1989 NaseriNosar, Pooya �����������������������������������������P572 Nashchekina, Oxana ��������������������������������������P1886 Nath, Siddharth ����������������������������������������������P1266 Nathaniel, Diane L. �������������������������������������������P887 Naumenko, Nataliia ����������������������������������������P2170 Navalkar, Ambuja ������������������������������������������� P1115 NavaneethaKrishnan, Saranya ����������������������P1347 Nave, Klaus-Armin �����������������������������������������P2172 Navel, Miriam ��������������������������������������������������P2144 Naves, Lígia A. ���������������������������������������������������P49 Nawaz, Kalim ���������������������������������������������������P668 Nazarenko, Inga ���������������������������������������������P1955 Nazarova, Elena ���������������������������������������������P1023 Nazockdast, Ehssan ���������������������������� P240, P1878 Nechemia-Arbely, Yael �������������������������������������P203 Nechiporuk, Alex ����������������������� P113,P1413,P2379 Nedelec, François �������������������������������� P988,P1448 Needleman, Daniel J. P243, P245, P973,P1016,P10 ��������������������������������������������22,P1878,P1888,P1910 Neely, Aaron M. ������������������������������������������������P263 Neisch, Amanda L. �����������������������������������������P1299 Neitzel, Leif R. ��������������������������������������������������P559 Nejad, Zahra B. �������������������������������������� P559,P785 Nejsum, Lene N. ����������������������������������� P642,P1665 Nekrasova, Oxana ������������������������������������������P2356 Nelliat, Anjali R. ������������������������������������������������P185 Nelman-Gonzalez, Mayra A. ��������������������������P2238 Nelms, Sheldon ����������������������������������������������P2135 Nelson, Branden ���������������������������������������������P2481 Nelson, Celeste M. �������������������������������������������P607 Nelson, David E. ���������������������������������������������P2417 Nelson, Deirdre A. ��������������������������������������������P761 Nelson, Jessica C. ������������������������������������������P2136 Nelson, Jonathan �������������������������������������������P1365 Nelson, Katherine ���������������������������������������������P505 Nelson, Richard ����������������������������������������������P1626 Nelson, William J. ��������P1464,P1466,P1467,P2224, ������������������������������������������������������������������������P2108 Nemirovsky, Oksana ��������������������������������������� P1151 Nesterova, Tatyana �����������������������������������������P2043 Nesvizhskii, Alexey �������������������������������������������P390 Nettesheim, Guilherme �������������������������������������P124 Neufeld, Thomas P. ����������������������������������������P1299 Neukranz, Yannika �������������������������������������������P216 Neuman, Keir C. ���������������������������������������������P1539 Neumann, Beate ������������������������������������������������P34 Neunuebel, Ramona ��������������������������������������P2425 Neville, Jessica L. ����������������������������������� P177,P476 Nevo-Yassaf, Inbar �������������������������������������������P415 Newman, Trent �����������������������������������������������P1869 Newmeyer, Donald D. ������������������������������������P2167 Nezich, Catherine �������������������������������������������P2331 Ng, Ashley �������������������������������������������������������� P111 Ng, Davis ���������������������������������������������P1192,P1513 Ng, Kah Ying ��������������������������������������������������P1333 Nganou, Gerry ������������������������������������������������P2343 Ngezahayo, Anaclet ���������������������� P260,P629,P633 Ngo, Anh ���������������������������������������������������������P1365 Ngsee, Johnny K. ������������������������������ P1515, P1517 Nguyen, Jennifer ��������������������������������������������P2164 Nguyen, Katrina T. ���������������������������������� P800,P808 Nguyen, Ken C. ������������������������������������������������P992 Nguyen, Lam T. ����������������������������������������������P1851 Nguyen, Thi A. ��������������������������������������������������P848 Nguyen, Tra H. �����������������������������������������������P1600 Nguyen, Truc ��������������������������������������������������P2326 Ngwa, Wilfred ���������������������������������������������������P327 Nham, Sang-Uk ������������������������������������������������P663 Nicastro, Daniela ����������������������������������������������P997 Nicholson, Joshua ��������������������������������������������P241 Nieberler, Matthias �������������������������������������������P618 Niedenthal, Rainer ������������������������������������������P2271 Niekamp, Stefan ���������������������������������������������P1766 Nielsen, Brian �������������������������������������������������P1839 Nielsen, Torsten ���������������������������������������������� P1151 Nielson, Matthew �������������������������������������������� P1147 Niemi, Jon P. ���������������������������������������������������P1314 Niemi, Rasmus �������������������������������������������������P628 Niethamer, Terren K. ���������������������������������������P1585 Nieto-Lima, Betzabe ���������������������������������������P2482 Nihei, Chiho ����������������������������������������������������P1691 Niihara, Yutaka �����������������������������������������������P2314

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Nijenhuis, Wilco ����������������������������������������������P2358 Nijmeijer, Bianca ���������������������������������������������P1657 Nikolajczyk, Barbara ���������������������������������������P1566 Nikolaus, Petra �������������������������������������������������P947 Nikonov, Sergei ����������������������������������������������P1387 Nikouli, Sofia ��������������������������������������������������P2371 Nilles, Amy ��������������������������������������������������������P524 Nilles, Nadine ���������������������������������������������������P371 Nilson, Ashley N. ��������������������������������������������P1531 Ning, Chenfei ����������������������������������������������������P519 Nirschl, Jeffrey J. ��������������������������������������������P1307 Nischan, Nicole ����������������������������������������������P1370 Nishida, Kazumichi M. ��������������������������������������P857 Nishida, Norifumi �������������������������������������������� P1107 Nishikawa, Atsushi �������������������������������������������P379 Nishimura, Syo �����������������������������������������������P1018 Nishimura, Yukako ��������������������������������������������P449 Nishina, Masami ��������������������������������������������� P1107 Nishina, Momoko ��������������������������������������������P1758 Nishioka, Tomoki ��������������������������������������������P2195 Nishizuka, Makoto ������������������������������ P1638,P1981 Nissen, Kelly E. ���������������������������������������������� P1179 Nissenson, Robert A. ����������������������������������������P813 Nistér, Monica ���������������������������������������������������P519 Nita-Lazar, Aleksandra �����������������������������������P2017 Nithianantham, Stanley ���������������������� P1789,P1795 Nitta, Ryo ��������������������������������������������������������P1750 Niwa, Shinsuke ���������������������������������������P112, P114 Nixon-Abell, Jonathon ������������������������������������P2139 Niyogi, Krishna ����������������������������������������������� P1189 Niyogi, Sayantanee ����������������������������������������P1261 Nizard, Carine ������������������������� P2310,P2402,P2403 Noble, Amanda R. ������������������������������������������P1098 Nobuyasu, Koga �����������������������������������������������P646 Noda, Masami ��������������������������������������������������P725 Noda, Takeshi ������������������������������������� P1392,P2317 Nogales, Eva ��������������������������� P1174,P1787,P1844 Noguchi, Masafumi �����������������������������������������P2317 Noguchi, Takako ���������������������������������������������P1625 Noh, Hyun Ju ��������������������������������������������������P2345 Noh, Woo Chul �����������������������������������������������P1937 Noll, Rebecca R. ��������������������������������������������P2425 Nolta, Jan ���������������������������������������������������������P884 Nomizu, Motoyoshi ����������������������������� P2291,P2336 Nomura, Dan K. ����������������������������������������������P1530 Noordstra, Ivar ������������������������������������������������P2358 Norby, Ellen C. ������������������������������������������������P1812 Norden, Caren ��������������������������������������������������P484 Nordenfelt, Pontus ��������������������������������� P646, P662 Nordmeier, Senny ��������������������������������� P337,P1977 Noren, Benjamin E. ����������������������������������������P1884 Norflus, Fran �������������������������������������������������������P14 NoriegaGuerra, Heydi ������������������������������������ P1164 Norlin, Nils ������������������������������������������������������P2264 Norris, Carolyn �������������������������������������������������P393 Norris, Stephen R. ��������������������������������������������P127 Norstad, Matthew ���������������������������������������������P793 Norstrom, Eric ���������������������������������������������������P401 Northcote, Peter ���������������������������������������������P1787 Northcott, Josette �������������������������������������������P1997 Northcott, Paul A. �������������������������������������������P1963 Nosanchuk, Josh ��������������������������������������������P1802 Noshahi, Faryal G. �������������������������������������������P816 Nossova, Nadya �����������������������������������������������P439 Notbohm, Jacob ���������������������������������������������P2225 Noureen, Aasma ���������������������������������������������P2309 NouriNejad, Daniel �����������������������������������������P1940 Novak, Ivon T. �������������������������������������������������P1230 Nowosad, Ada ������������������������������������������������P2239 Nozaki, Shoehi �����������������������������������������������P1833 Nozaki, Tomoyoshi �����������������������������������������P2079 Nozawa, Kaori ��������������������������������������������������P753 Nualart, Francisco J. ��������P514,P672,P1007,P2114 Nuccio, Arthur �������������������������������������������������P2017 Nuebler, Johannes �����������������������������������������P1990 Nuhn, Jacob ���������������������������������������������������P2258 Nunes, Laiz ����������������������������������������������������P2292 Nunes, Lydia ���������������������������������������������������P2171 Nunesde Almeida, Francisca ����������������������������P460 Nuñez, Illyce ������������������������������������������� P360,P447 Nunez de Villavicencio Díaz, Teresa ��������������P1389 Nunnari, Jodi ������������������������������� P520,P550,P1328 Nunomura, Wataru �����������������������������������������P2181 Nüske, Elisabeth ����������������������������������������������P626

Nussenzweig, Andre �����������������������������������������P917 Nyamay’Antu, Alengo M. ����������������������������������P865 Nyman, Tuula ���������������������������������������������������P315 Nymark, Soile ���������������������������������������������������P637

O

Oakes, Patrick W. �����������������������������������P611, P613 Oakey, John S. ���������������������������� P378,P505,P1884 Oakley, Berl R. ������������������������������������������������P1052 Obadia, Benjamin �������������������������������������������P2421 Obara, Christopher J. ������������������������ P2139, P2143 Obayomi, Bukola ��������������������������������������������P1641 Obbineni, Jagan M. ����������������������������������������P1001 Ober, Raimund J. �����������������������������������������������P39 Oberhofer, Angela ��������������������������������������������P963 Occhipinti, Patricia ������������������������������������������P1669 Ochmann, Sarah �������������������������������������������� P1211 Ochoa, Manuel �����������������������������������������������P1235 Ochoa, Stacy D. ���������������������������������������������P1546 OchoaMikrut, Stacy ����������������������������������������P1076 O’Connell, Kevin �����������������������������������������������P205 O’Connell, Meghan E. ��������������������������������������P895 Odabasi, Ezgi �������������������������������������������������P1823 Odde, David J. ��������������������������� P132,P1805,P2233 Odenheimer, David �����������������������������������������P1223 O’Donnell, Allyson F. ����������������������������������������P850 O’Donnell, Brooke ������������������������������������������P1940 Odorizzi, Greg ������������������������������������������������P2082 O’Dowd, Roisin M. ������������������������������������������P1469 Oeding, Stefanie �����������������������������������������������P947 Oegema, Karen � P187,P1038,P1076,P1546,P1855, ������������������������������������������������������������ P1863,P1902 O’Farrell, Patrick H. ����������������������������������������P1551 Offer, Steven M. ���������������������������������������������� P2011 Ogas, Talysa ���������������������������������������������������P1928 Ogawa, Yukari ������������������������������������������������ P1107 Oh, Doogie �������������������������������������������������������P243 Oh, Goo Taeg ������������������������������������� P2345,P2347 Oh, Hye Jin �������������������������������� P688,P2328,P2454 Oh, Jee-Woo ��������������������������������������������������P2428 Oh, Jin-Woo ����������������������������������������������������P2335 Oh, Nuri ������������������������������������������������������������P328 Oh, Somi �������������������������������������������������������� P1159 Oh, Sung-Man �������������������������������������� P677,P2413 Ohashi, Kazumasa �������������������������������������������P610 Ohi, Ryoma ����������������������������������������������������P1751 Ohkawa, Taro �������������������������������������������������P1731 Ohsugi, Miho �������������������������������������� P1755,P2030 Ohta, Midori ����������������������������������������������������P1073 Ohyama, Takashi ��������������������������������������������P2009 Oiwa, Kazuhiro �������������������������������������������������P998 Oka, Toshihiko ��������������������������������������������������P525 Okada, Hatsumi ������������������������������������������������P744 Okada, Yasushi �� P62,P115,P144,P577,P874,P1763, ����������������������������������������������������������������������������� P1778 Okajima, Takaharu ������������������������������ P1459,P1703 Okamoto, Norihiro ������������������������������������������P2304 Okamoto, Tevor ����������������������������������������������P1673 Oki, Aderemi �����������������P1494,P1917,P1918,P1922 Oki, Eiji �����������������������������������������������������������P1018 Okorie, Chiamaka L. �����������������������������������������P297 Okreglak, Voytek ����������������������������������������������P712 Oksenberg, Jorge R. ��������������������������������������P1639 Oktay, Maja H. ������������������������������������������������ P1136 Ökten, Zeynep ���������������������������������������� P126,P963 Okumichi, Hideki ��������������������������������������������P1322 Okumoto, Kanji �����������������������������������������������P2152 Olarte, María-Jesús ����������������������������������������P2149 Oldenbourg, Rudolf ������������������������������ P646,P1669 Oldrini, Barbara ������������������������������������������������P288 Olichon, Aurélien ����������������������������������������������P866 Oliferenko, Snezhana ������������������������� P1745,P1853 Oliveira, Alexandre L. �������������������������������������P1505 Oliveira, Fabiola S. �������������������������������������������P889 Oliveira, Leticia P. ������������������������������� P1500,P1505 Oliviera, Paulot. �������������������������������������� P659,P818 Oliveira, Regiana ��������������������������������������������P1592 Oliveira, Ricardo B. ������������������������������������������P636 Oliver, Constance ���������������������������������������������P585 Oliver, Emily E. �������������������������������������������������P695 Oliver, Kendra H. ������������������������������������������������P26 Olmos, Yolanda ������������������������������������������������P497 Olofsson, Sarah ����������������������������������������������P2126

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Olshen, Adam �������������������������������������������������P2319 Olson, Marin G. ������������������������������������������������P353 Olson, Norman H. �������������������������������������������P2167 Olson, Sara K. ������������������������������������������������P1554 Oltrabella, Francesca �������������������������������������P1265 Olzmann, James A. ���������������������������� P1530,P2326 Omabegho, Tosan ��������������������������������������������P957 Omelchenko, Tatiana A. ������������������������������������P324 Omer, Safia ����������������������������������������������������P1771 Omran, Heymut ������������������������������������������������P152 Ona, Lorena ��������������������������������������������������� P1133 Onalla, Hadil ��������������������������������������������������� P1146 Onami, Shuichi �������������������������������������������������P744 O’Neil, Colin ���������������������������������������������������P1682 ONeill, Audrey K. ��������������������������������������������P1585 O’Neill, Rachel J. ��������������������������������������������P2015 Oneto, Michele �������������������������������������������������P924 Ong, Qunxiang ���������������������������������������������������P54 Ong, SeowTheng ���������������������������������������������P886 Onken, Michael D. ������������������������������������������P2423 Ono, Shoichiro ��������������������������������������������������P901 Onochie, Obianamma E. ��������������������������������P2247 Oo, Aung K. ����������������������������������������������������P1946 Opalko, Hannah E. �����������������������������������������P1403 Opara, Sienna ������������������������������������������������P2341 Opekarová, Miroslava ��������������������������������������P357 Opferman, Michael �����������������������������������������P2037 Ophardt, Henry D. ������������������������������������������P2209 Opoku-kusi, George ���������������������������������������P2067 Orange, Jordan S. ������������������������������������ P96,P916 Ordonez, Alejandra ����������������������������������������� P1166 O’Reilly, Fergal �����������������������������������������������P1660 O’Reilly Pol, Tom ��������������������������������������������P2379 Ori, Alessandro �����������������������������������������������P2092 Orjalo, Arturo V. ����������������������������������������������P1673 Orlovsky, Igor V. ��������������������������������������������� P1169 Oro, Anthony E. ����������������������������������������������P1373 Orofino, Joseph ����������������������������������������������P1375 O’Rourke, Allison R. ���������������������������������������P1715 O’Rourke, Brian ����������������������������������������������P1802 Orr, Bernardo ����������������������������������������������������P218 Orr, Brent A. ����������������������������������������������������P1963 Ortega, Carina ������������������������������������������������ P1106 Ortega, Fabian E. ������������������������������� P1619,P2409 Orth, Kim �������������������������������������������� P1506,P2414 Orthaus-Mueller, Sandra ��������������������������������P1658 Ortiz, Daniel ���������������������������������������������������� P1139 Ortiz, Natalie ���������������������������������������������������P2142 Ortiz, Rina ������������������������������������������������������P2243 Ortiz-Soto, Gabriela ������������������������������������������P276 Ortmeier, Steven B. ������������������������������������������P385 Ortolano, Natalya �������������������������������������������P2382 Osada, Shigehiro �������������������������������� P1638,P1981 Oses-Prieto, Juan A. ������������������������� P1420, P2121 O’Shaughnessy, Ben �������������������������� P1853,P1854 Osman, Christof ���������������������������������������������P1334 Osmani, Nael �������������������������������������������������� P1138 Osmani, Steve ������������������������������������������������P1209 Ostedgaard, Lynda S. ���������������������������������������P147 Oster, George ���������������������������������������������������P724 Östlund, Cecilia ������������������������������������������������P462 OSullivan, Gerry ���������������������������������������������P1660 Osunbayo, Olaolu ���������������������������������������������P128 Oszmiana, Anna �����������������������������������������������P916 Otoole, Eileen T. ��������������������������������� P1020,P1023 Otoole, Peter ��������������������������������������������������P1098 Ott, Carolyn M. �����������������������������������������������P1834 Otterpohl, Karla L. ��������������������������������������������P385 Otto, Annette ��������������������������������������������������P2084 Ou, Guangshuo ���������������������������������� P1820,P1857 Ou, Guanqing ������������������������������������������������� P1161 Oudin, Madeleine ������������������������������������������� P1163 Ouellet, Eric ������������������������������������������������������P884 Ovchinnikov, Sergey �����������������������������������������P802 Overby, Darryl R. ����������������������������������������������P727 Oviedo, María J. ���������������������������������������������P1007 Oviedo, Norma A. ���������������������������������������������P342 Owa, Mikito �����������������������������������������������������P1001 Owen, David L. �����������������������������������������������P1024 Owen, Deanna �������������������������������������������������P303 Owen, Leanna M. �������������������������������������������P2225 Owens, Kjerstin M. ����������������������������������������� P1132 Oyarzún, Carlos F. ������������������������������������������P1985 Ozarkar, Snehal ����������������������������������������������P2235

Oztug Durer, Zeynep A. ������������������������������������P101

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P.Nathamgari, S.Shiva ������������������������������������P1449 Paar, Hannah �������������������������������������������������P2371 Pacas, Jose ������������������������������������������������������P828 Pache, Roland A. ������������������������������������������������P69 Pacitto, Regina �����������������������������������������������P1277 PadashBarmchi, Mojgan ����������������������������������P302 Paddison, Patrick ���������������������������������������������P788 Pagnotta, Joespeh �����������������������������������������P1588 Pal, Debjani ����������������������������������������������������P1960 Palani, Saravanan ������������������������������ P1745,P1853 Palayret, Matthieu ������������������������������������������P2193 Palazzo, Elisabetta �����������������������������������������P2403 Pal-Ghosh, Sonali ������������������������������������������P2265 Paliulis, Leocadia V. ��������������������������������� P27,P220 Palmeri, Diana ������������������������������������������������P1603 Palmfeldt, Johan �����������������������������������������������P642 Palmisano, Nicholas J. �������������������������������������P436 Pan, Chong-xian �����������������������������������������������P277 Pan, Deng ������������������������������������������������������P2334 Pan, Junmin ����������������������������������������� P153,P1816 Pan, Xiang ������������������������������������������������������P1279 Panday, Arvind ������������������������������������������������P2007 Pandey, Mritunjay ���������������������������������������������P301 Pando-Robles, Victoria �����������������������������������P1678 Pandya, Unnati M. ��������������������������������������������P665 Pani, Ariel M. ������������������������������������������������������P66 Panic, Marko ����������������������������������������������������P210 Panicker, Leelamma M. ������������������������������������P877 Pannucci, Nicole ��������������������������������� P1555,P1697 Pante, Nelly �����������������������������������������P1151,P2049 Panthi, Asmita ������������������������������������������������P2200 Panzica, Michelle T. ���������������������������� P1876,P1905 Paoletti, Anne �������������������������������������������������P1073 Paolillo, Vitoria ������������������������������������������������P1052 Papachristou, Evaggelia K. ����������������������������P1074 Papanikou, Effrosyni �����������������������������������������P422 Papoian, Garegin A. ��������������������������� P1709,P2017 Pappalardo, Zachary ����������������������������������������P867 Pappoe, Herman ��������������������������������������������P2392 Pappu, Rohit V. �������������������������������������������������P714 Parada, Luis F. �����������������������������������������������P1955 Parada, Monica ������������������������������������������������P778 ParedesDiaz, Felipe I. ��������������������������������������P527 Paredez, Alexander R. �������������������������������������P934 Parent, Sophie �������������������������������������P1119,P2212 Pargett, Michael �����������������������������������������������P560 Parikh, Aashka �����������������������������������������������P1872 Parilla, Jacqueline ������������������������������������������ P1193 Park, Bridget S. ����������������������������������������������P1519 Park, Chul-Seung �������������������������������������������P1378 Park, Dae-Ryung ����������������������������������������������P568 Park, Daniel ������������������������������������������������������P102 Park, Dongeun �����������������������������������������������P1647 Park, Elizabeth M. ��������������������������������������������P208 Park, GyeongYeon �����������������������������������������P1563 Park, Hay-Oak O. ���������������������������������������������P468 Park, Hee-Sae ������������������������������������ P1381,P1382 Park, Hwa-Jeong ��������������������������������������������P1708 Park, Hyeonsoo ������������������������������������������������P657 Park, In-Chul ���������������������������������������� P295,P1937 Park, Intae ������������������������������������������������������P1094 Park, James H. �����������������������������������������������P1786 Park, JeongWoo ���������������������������������������������P1807 Park, Ji-Eun ����������������������������� P2430,P2431,P2432 Park, JiHoon ���������������������������������������������������P1978 Park, Ji-In ���������������������������������������������������������P329 Park, Jong-Wan ����������������������������������������������P1436 Park, Joo-Dong ����������������������������������������������P1978 Park, Joori ��������������������������������������������������������P479 Park, Joseph H. ����������������������������������������������P1520 Park, JuEun ������������������������������������������������������P184 Park, Jung-Won ����������������������������������������������P2020 Park, Junsoo ��������������������������������������������������P2071 Park, Ki-Sook �������������������������������������������������P1443 Park, Kyeong Ah ��������������������������������� P1093,P2205 Park, Kyung-Soon ��������������P328,P329,P330,P1978 Park, Min Hee �������������������������������������������������P2461 Park, Myo Hyeon ������������������������������������ P274,P567 Park, Pil-Hoon ��������������������������� P688,P2328,P2454 Park, Rackhyun ����������������������������������������������P2071

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Park, Sang-Hyun ��������������������������������������������P2196 Park, Seok S. �������������������������������������������������P1094 Park, SeongJi ������������������������������������� P1932,P1933 Park, Seungman ���������������������� P1462,P2241,P1698 Park, Sheldon �������������������������������������������������P2280 Park, Sin-Hye �������������������������������������������������P2329 Park, Sojung ���������������������������������������������������P1092 Park, Soo-Ah �������������������������������������������������� P1129 Park, Soo Hyun ������������������������������������������������P120 Park, Soojin ����������������������������������������������������P2286 Park, Sujin ��������������������������������������������������������P583 Park, TeaJun ��������������������������������������������������� P1142 Parker, Laurie �������������������������������������������������P1236 Parker, Sarah ���������������������������������������������������P664 Parker-Thornburg, Jan �������������������������������������P869 Parks, Lois G. ���������������������������������������������������P573 Parlak, Mahmut ����������������������������������������������P1992 Parmely, Tari �����������������������������������������������������P365 Parnaik, Veena K. ������������������������������� P2025,P2026 Parra, Amalia ����������������������������������������������������P246 Parra, Karlett J. ����������������������������������������������P1632 Parra-Barrera, Alberto ������������������������������������P2452 Parrillo, Allegra �����������������������������������������������P1693 Parrish, Jay Z. �������������������������������������� P621,P1664 Parson, Jan P. ������������������������������������������������P1966 Parsons, Maddy �����������������������������������������������P642 Parsons, Travis T. �������������������������������������������P1576 Parsons-White, Amy B. ����������������������������������P2404 Partida, Diana �������������������������������������������������P1554 Pasakarnis, Laurynas �������������������������������������P2364 Pascetti, Erica M. ���������������������������������������������P587 Pascual, Agnes S. ������������������������������������������P2263 Pasini, Silvia �����������������������������������������������������P493 Pasolli, H.Amalia ��������������������������������������������P2139 Pasos, Julio ����������������������������������������������������P1777 Pastar, Irena �����������������������������������������������������P578 Pastoriza, Jessica ��������������������������������������������P341 Pastor-Pareja, Jose C. ��������������������������� P413,P980 Pastor Peidro, Ana �������������������������������������������P210 Patel, Aanand A. �����������������������������������������������P101 Patel, Avi ��������������������������������������������������������� P1174 Patel, Avinash ���������������������������������������������������P700 Patel, Bhaven B. �����������������������������������������������P559 Patel, Bhavin B. ����������������������������������������������P1687 Patel, Jay ����������������������������������������������������������P890 Patel, Krishnam ������������������������������������������������P395 Patel, Mili B. ���������������������������������������������������P1570 Patel, Millan ���������������������������������������������������� P2113 Patel, Mohak ��������������������������������������������������P2225 Patel, Mulchand ����������������������������������������������P2172 Patel, Pooja N. �����������������������������������������������P1042 Patel, Rekha C. ������������������������������������������������P676 Patel, Shreya ��������������������������������������������������P2457 Pathak, Amrita ��������������������������������������������������P781 PatinoDescovich, Carlos ��������������������������������P1850 Paton, Adrienne W. �������������������������������������������P708 Paton, James C. �����������������������������������������������P708 Patriarchi, Tommaso ����������������������������� P293,P2125 Patrick, Kristin ������������������������������������������������ P1179 Patrushev, Maksim V. �������������������������������������P2381 Pattamatta, Preeti ���������������������������������������������P890 Patterson, George H. ���������������������������������������P415 Patterson, Kayne ��������������������������������������������P2251 Patterson, Michael ������������������������������������������P2086 Patton, Christopher J. ���������������������������������������P281 Patwardhan, Anand ����������������������������������������P1288 Paul, Nikki R. ��������������������������������������������������P1720 Paulo, Joao A. ������������������������������������ P1251,P2330 Paulson, Amanda ���������������������������������������������P323 Paulson, James R. �������������������������������������������P685 Pavelka, Norman ��������������������������������������������P1214 Pavesi, Andrea �����������������������������������������������P1689 Pavey, Sandra ������������������������������������������������P1959 Pavin, Nenad ����������������������������������������������������P186 Pavlik, Jacqueline �������������������������������������������P1003 Pavlos, Nathan J. �������������������������������������������P2155 Pavlyk, Iuliia ���������������������������������������������������P1743 Pays, Karl �������������������������������������������������������P2443 Pazevic, Alex ������������������������������������������������������P49 Pearson, Guy J. ����������������������������������������������P2095 Peat, Emma M. �����������������������������������������������P1893 Pechuan, Ximo �����������������������������������������������P1295 Pedchenko, Vadim K. �������������������������������������P1499 Pedersen, Gitte A. ��������������������������������������������P642

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AUTHOR INDEX Pedersen, Lotte B. �������������������������������� P146,P1839 Pedersen, Nina M. ��������������������������������������������P404 Pederson, Thoru ���������������������������������������������P1989 Pedro, Brian ��������������������������������������������������� P1143 Peeples, William ���������������������������������������������P1237 Peer, Natalie �����������������������������������������������������P747 Peersen, Olve B. ����������������������������������������������P384 Pegoraro, Gianluca ����������������������������������������P1217 Peifer, Mark ��������������������������������� P459,P842,P1558 Peitl-Filho, Oscar ����������������������������������������������P817 Pelaseyed, Thaher �������������������������������������������P466 Pelham, Hugh �������������������������������������������������P1534 Pellacani, Claudia ���������������������������������������������P204 Pellegrini, Matteo ��������������������������������������������P2392 Pelletier, Cassandra ���������������������������������������P1881 Pellman, Jason �����������������������������������������������P2266 Peloza, Kim ������������������������������������������������������P440 Peña, Eduardo �������������������������������������������������P291 Pendi, Kasim ��������������������������������������������������P1504 Pendleton, Alex ����������������������������������������������P1928 Peng, Bing ��������������������������������������������P358, P1199 Peng, Chien-Chung ����������������������������������������P1450 Peng, Grace E. �����������������������������������������������P1417 Peng, Jamy C. ��������������������������������������������������P751 Peng, Yun ���������������������������������������������������������P621 Pennycook, Betheney R. ��������������������������������P1050 Penuela, Silvia �������������������������� P430,P2272, P1940 Pepin, Danielle �������������������������������������������������P858 Pepperkok, Rainer ������������������������� P34,P503,P2092 Perchey, Renaud ��������������������������������������������P2239 Perdrix-Rosell, Anna �����������������������������������������P497 Pereira, Francisco J. ��������������������������������������P1274 Pereira, Karina D. �������������������������������������������P1376 Perera, Rushika ����������������������������������������������P2326 Perera, Sumeth M. �������������������������������������������P339 Perez, Adam M. ���������������������������������� P1663,P1672 Perez, Alejandra �����������������������������������������������P529 Perez, Franck ���������������������������� P866,P1287,P2092 Perez, Philippe �����������������������������������������������P2302 Perez, Pilar �����������������������������������������������������P2099 Perez-Laspiur, Juliana ������������������������ P1974,P1975 Perez-Neut, Mat ���������������������������������������������P2246 PerezRiveros, Paola �����������������������������������������P576 Perez-Salas, Ursula �����������������������������������������P545 Perez-Torres, Armando ����������������������������������P1234 Perfettini, Jean-Luc ���������������������������������������� P1153 Peri, Francesca ����������������������������������������������P2264 Perillo, Margherita ��������������������������������������������P363 Perissi, Valentina �������������������������������� P1375,P1566 Perkins, Andy �������������������������������������������������P2012 Perlaza, Karina �����������������������������������������������P2154 Perlson, Eran ����������������������������������������������������P415 Pero, MariaElena ����������������������������������������������P493 Perrais, David �������������������������������������������������P2090 Perrimon, Norbert ��������������������������������� P885,P2386 Perrin, Benjamin J. �������������P108,P894,P926,P1715 Perrud, Maria E. ���������������������������������������������P2226 Persaud, Leah E. ����������������������������������������������P262 Pertz, Olivier �����������������������������������������������������P717 Peschek, Jirka ������������������������������������� P712, P1509 Pessino, Veronica �������������������������������������������P1677 Petek, Natalie A. ���������������������������������������������P1735 Peter, Matthias ��������������������������������������� P710,P717 Peterman, Eric M. ���������������������������������������������P178 Petermann, Eva ������������������������������������������������P229 Peternel, Spela �����������������������������������������������P1605 Peters, Bjoern �������������������������������������������������P2167 Peters, Christian ���������������������������������������������P2121 Peters, Jan-Michael ����������������������������������������P1990 Peterson, Clark W. �����������������������������������������P1530 Peterson, Deforrest ����������������������������������������P1917 Peterson, Kirk L. ���������������������������������������������P2266 Peterson, Kylie B. ������������������������������������������� P1118 Peterson, Mikayla �������������������������������������������P1958 Peterson, Paige ����������������������������������������������P1318 Peterson, Timothy R. ����������������������������������������P553 Petithory, Tatiana ��������������������������������������������P2216 Petreaca, Melissa L. ���������������������������������������P2438 Petrecca, Kevin ������������������������������������������������P910 Petrie, Ryan J. ��������������������������������������������������P599 Petrovic, Petar ��������������������������������������������������P652 Petzold, Chris ���������������������������������������������������P504 Peuhu, Emilia ���������������������������������������������������P650

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Peyro, Mohaddeseh ������������������ P486,P2033,P2034 Pfanzelter, Julia ����������������������������������������������P1599 Pfeffer, Bruce A. ������������������������������������������������ P511 Pfeifer, Charlotte R. �����������������������������P1141,P1228 Pfeil, Dan C. ��������������������������������������� P1361,P2388 Phiel, Christopher J. ���������������������������������������P1397 Phillippe, Jean-Marc ���������������������������������������P1575 Phillips, Joanna J. ������������������������������������������ P1160 Phillips, Melissa ������������������������������������������������P426 Phillips, Rob �����������������������������������������������������P830 Phua, Siew C. �������������������������������������������������P1819 Pi, Fuwei �����������������������������������������������������������P929 Piasta, Kene ���������������������������������������������������P1682 Picard, Louis-Philippe �������������������������������������P1866 Picariello, Hannah S. �������������������������������������� P1102 Picart, Catherine ���������������������������������������������P2289 Picas, Laura ���������������������������������������������������P1447 Picco, Andrea ���������������������������������������������������P391 Pichaud, Franck �����������������������������������������������P460 Pichon, Chloé �������������������������������������������������P2162 Pickrell, Alicia M. ��������������������������������� P531, P2159 Picotti, Paola ����������������������������������������������������P710 Pidoux, Alison L. ���������������������������������������������P1995 Piekarz, Katarzyna �������������������������������������������P236 Piekny, Alisa J. �������������������������������������� P769,P1086 Piel, Matthieu ��������������������������������� P376,P445,P917 Pielak, Gary J. ��������������������������������������������������P696 Pierre-elies, Priscillia ����������������������������������������P237 Pietilä, Mika ������������������������������������������������������P402 Pietka, Grzegorz ���������������������������������������������P1265 Pieuchot, Laurent ������������������������������� P2216,P2287 Pigino, Gaia ������������������������������������������������������P626 Pignatelli, Jeanine ������������������������������������������ P1136 Pilli, Ronaldo A. ����������������������������������������������P2308 Pim, David C. �������������������������� P1244,P1604,P1605 Pimentel, Edson R. ����������������������������� P1500,P1505 Pincelli, Carlo �������������������������������������������������P2403 Pincet, Frederic ������������������������������������������������P537 Pineda-Benítez, Lot ����������������������������������������P2482 Pineda-Vázquez, Dirce �����������������������������������P1234 Pinelli, Robert �������������������������������������������������P1580 Pines, Jon �������������������������������������������������������P1886 Ping, Holly A. ���������������������������������������� P524,P1345 Pingali, Hema V. ���������������������������������������������P1202 Pinheirode Souza, Ricardo �������������������������������P684 Pinon Hofbauer, Josefina ������������������������������� P1168 Pinot, Mathieu ������������������������������������������������P2218 Pinskey, Justine M. �������������������������������������������P569 Piper, Amanda ������������������������������������������������P1597 Piper, Robert ����������������������������������������������������P405 Pippa, Raffaella ����������������������������������������������P1676 Piquet, Léo ���������������������������������������������������������P95 Pirko, Yaroslav V. �������������������������������������������� P1177 Piruzyan, Mariam ������������������������������ P2338, P2429 Piszkiewicz, Samantha �������������������������������������P696 Pitman, Mary ��������������������������������������������������P2017 Pittman, Matthew �������������������������������� P1698,P2241 Piwowarski, Jan ����������������������������������������������P1954 Pizer, Barry ����������������������������������������������������� P1103 Plachta, Nicolas ����������������������������������������������P1549 Plair, Jennifer ��������������������������������������������������P1419 Planchon, Damien ������������������������������������������P1250 Platani, Melpomeni �����������������������������������������P1065 Playford, Martin ����������������������������������������������P1244 Plaza, Christelle ���������������������������������������������P2402 Pleiner, Tino ����������������������������������������������������P1666 Plitzko, Jürgen M. �������������������������������������������P2091 Ploegh, Hidde L. �����������������������������������������������P708 Plooster, Melissa �������������������������������� P1264,P2054 Ploper, Diego ��������������������������������������������������P1385 Plotnikov, Sergey V. ������������������������������ P620,P2242 Ploubidou, Aspasia ����������������������������������������� P2113 Plumb, Rachel ������������������������������������������������P1508 Plutoni, Cedric ������������������������������������������������P1434 Pocard, Marc �������������������������������������������������� P1153 Podlipaeva, Yulia ��������������������������������������������P1596 Podolski, Marija ������������������������������������������������P588 Poghosyan, Emiliya ������������������������������������������P996 Pogliano, Joseph ������������������������� P800,P808,P1735 Pogliano, Kit �������������������������������������������������������P35 Poidinger, Michael ������������������������������������������P1214 Poitelon, Yannick ��������������������������������������������P2172 Pokrovskaya, Irina D. ���������������������������������������P420 Polak, Bruno �����������������������������������������������������P186

Poletti, Mickael �������������������������������������������������P812 Politi, Antonio Z. �����������������������������������������������P232 Pollard, Daniel A. �������������������������������������������� P1191 Pollard, Luther W. ���������������������������������������������P100 Pollard, Thomas D. �����������������������������������������P1854 Pollenz, Richard S. �������������������������������������������P838 Pollock, Pamela M. �����������������������������������������P1442 Pollock, Raphael E. ����������������������������������������P1967 Pollock, Sam ��������������������������������������������������P1421 Pon, Liza A. ��������������������������������������� P1749, P2332 Ponder, Katelyn G. �������������������������������������������P673 Ponik, Suzanne M. ����������������������������������������� P1156 Pontabry, Julien ����������������������������������������������P1550 Pontasch, Josef ������������������������������������������������P188 Pontes, Bruno �������������������������������������������������P2287 Poole, Aaron R. ������������������������������������� P361, P812 Poolthong, Suchit �������������������������������������������P2453 Poon, Tak K. �����������������������������������������������������P553 Popow, Rachel ����������������������������������������������� P2116 Poprawski, Joanna �������������������������������������������P393 Porter, Mary E. ����������������������������������� P1012,P1814 Porter, Tequila �������������������������������������������������P1608 Porter-Kelley, Johanna M. ������������������������������P1608 Poser, Ina ������������������������������������������� P2092,P2094 Posthuma, George �������������������������������������������P999 Potapenko, Evgeniy ���������������������������������������P1598 Potter, Chloe �����������������������������������������������������P368 Potts, Gregory K. ��������������������������������������������P1687 Poudel, Susmita ���������������������������������������������P2067 Poumay, Yves �������������������������������������������������P1354 Pouwels, Jeroen �������������������������������������������������P72 Power, Katlin ��������������������������������������������������P2157 Powers, Joe S. �������������������������������������������������P757 Prabakaran, Indira ����������������������������������������������P97 Prabhakara, Chaitra ���������������������������������������P1569 Prabhu, K. S. �������������������������������������� P1640,P2418 Pradhan, Tirthadipa ����������������������������������������P2106 Prahl, Louis S. �������������������������������������� P132,P2233 Prahlad, Achintya ���������������������������������������������P964 Prak, Eline T. ����������������������������������������������������P827 Prakash, Manu ������������������������������������������� P17,P19 Pranadinata, Rama ����������������������������������������P1280 Pranoto, Inez K. ����������������������������������������������P2207 Prasad, Ashok ������������������������������� P305,P306,P723 Prasad, Rajendra ���������������������������������������������P542 Prasad, Rupali ������������������������������������� P539, P1513 Prasad, Sherry �����������������������������������������������P1566 Pravder, Harrison �������������������������������������������P1013 Pravoverov, Kristina ������������������������������������������P355 PreciadoLópez, Magdalena ����������������������������P2249 Preece, Daryl ��������������������������������������������������P1324 Preest, Marion ��������������������������������������������������P852 Prekeris, Rytis ����������������������������� P178,P310,P2104 Premartin, Fanny ����������������������������������������������P865 Prematilake, Keshika ����������������������������������������P412 Presley, John F. ����������������������������������������������P2147 Presta, Matthew ���������������������������������������������P1607 Priano, Christine ����������������������������������������� P13,P15 Price, Andrew J. ���������������������������������������������P2396 Price, Kari L. �����������������������������������������������������P171 Priestley, Rodney D. �����������������������������������������P714 Prieto, Anne L. ������������������������������������������������P1586 Primo, Luca ������������������������������������������������������P924 Primorac, Adriana �������������������������������������������P2310 Prinz, William ����������������������������������������������������P550 Prior, Ian �����������������������������������������������������������P235 Priyadarshini, Pallavi ����������������������������������������P890 Probst, Dimitri ��������������������������������������������������� P611 Proenca, Andre R. ������������������������������������������P1376 Prohaska, Steffen ���������������������������������������������P240 Proia, Richard �������������������������������������������������P1364 Prophete, Liautaud �����������������������������������������P1762 Prosperi, Jenifer R. ��������������������������������P464,P1125 Prosser, Benjamin L. ����������������������������������������P600 Prosser, Derek C. ����������������������������������� P386,P393 Proudfoot, Kathleen G. �����������������������������������P1885 Provencher, Edward ���������������������������������������P1203 Provenzano, Paolo �����������������������������������������P2259 Pruitt, Beth L. ��������������������������� P1466,P1695,P2224 Prunuske, Amy J. ����������������������� P832,P1623, P842 Pruss, Rebecca M. �����������������������������������������P2451 Pruyne, David W. ������������������������������������������������P99 Przybyla, Laralynne ����������������������������������������P2373 Pshezhetsky, Alexei ������������������������������������������P501

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Puccia, Christopher ����������������������������������������P1046 Puettmann, Paul ���������������������������������������������P1460 Puissant, Emeline �������������������������������������������P1267 Pujato, Mario ��������������������������������������������������P1295 Puliafito, Alberto �����������������������������������������������P924 Punzalan, Rubio ���������������������������������������������P2144 Purde, Vedud ����������������������������������������������������P191 Pushkareva, Valentina ������������������������������������P1596 Puthenveedu, Manojkumar ����������������������������P2135 Pylypenko, Olena �������������������������������������������P1862 Pyun, Junghoon �����������������������������������������������P771

Q

Qi, Lei S. �����������������������������������������������������������P860 Qi, Robert Z. ���������������������������������������������������P1078 Qian, Hui ��������������������������������������������������������P1935 Qian, Xuyu ��������������������������������������������������������P962 Qian, Yi �������������������������������������������������������������P427 Qiang, Li �����������������������������������������������������������P309 Qiang, Liang ��������������������������������������� P1320,P1784 Qin, An ������������������������������������������������������������P2155 Qin, Bo ������������������������������������������������� P254,P1792 Qin, Peiwu ������������������������������������������������������P1992 Qin, Yidan ���������������������������������������������������������P354 Qiu, Andong ����������������������������������������������������P1654 Qiu, Haiyan �����������������������������������������������������P2137 Qiu, Ji �������������������������������������������������������������P2425 Qiu, Wei-Gang ������������������������������������������������P2422 Qu, Chunxu ������������������������������������������������������P751 Qu, Dan ������������������������������������������������������������P181 Qu, Fangfei �������������������������������������������������������P388 Qu, Shuai �������������������������������������������������������P1584 Qu, Xiaoyi ����������������������������������������������� P492,P493 Quach, Nicolas ���������������������������������������������������P67 Quadri, Marika ������������������������������������������������P2403 Quaile, Andy ���������������������������������������������������P1280 Quake, Stephen ���������������������������������������������P1681 Quarantotti, Valentina �������������������������������������P1074 Quayle, John M. ��������������������������������������������� P1148 Quenet, Delphine ��������������������������������� P353,P2000 Quéniot, Stéphanie �����������������������������������������P1628 Quest, Andrew F. �������������������������������� P1422,P2243 Quezada, Claudia A. ��������������������������������������P1985 Quidwai, Tooba �����������������������������������������������P1448 Quinlan, Margot E. ���������������P86,P101,P102,P1728 Quinlivan-Repasi, Vanessa H. ���������������� P56,P1352 Quinn, Anne Marie M. �������������������������������������P2208 Quintanilla, Isabel ���������������������������������������������P241 Quintero, Omar A. ������������������P46,P575,P948,P951 Quintyne, Nicholas J. ���������������������������������������P234

R

Ra, Jeong-Sic ���������������������������������������������������P825 Raab, Matthew �������������������������������������������������P376 Raaijmakers, Jonne A. �������������������������������������P200 Rabalski, Adam ����������������������������������������������P1389 Rabokon, Anastaisiya N. �������������������������������� P1177 Raciti, Christopher ������������������������������������������P1317 Radder, Josiah E. �������������������������������������������P2164 Radford, Sarah J. �������������������������������������������P1872 Radhakrishnan, Prathima �������������������������������P1619 Radhakrishnan, Ravi �����������������������������P438,P1161 Radvanyi, François �������������������������������������������P500 Raedschelders, Koen ���������������������������������������P664 Rael, Victoria E. ���������������������������������� P2324,P2333 Rafelski, Susanne M. �������P53,P356, P1326,P1335, .............................................................P1336,P2306 Raftery, Laurel A. ��������������������������������������������P1576 Raghu, Deepthi ����������������������������������������������P2277 Raghunathan, Krishnan ���������������������� P1357,P1536 Raghunathan, Vijay ����������������������������������������P1502 Raghunathan, VijayKrishna ����������������������������P2295 Ragkousi, Katerina ����������������������������������������� P2119 Ragoussis, Ioannis ���������������������������������������������P52 Rahajeng, Juliati ���������������������������������������������P1863 Rahman, Afrida �����������������������������������������������P1586 Rahman, Mariah ���������������������������������������������P1788 Rahman, Mohammad M. ����������������������������������P369 Rahnamoun, Homa ���������������������������������������� P1191 Rain, Jean-Christophe ��������������������������������������P866 Rairdan, Xin Y. ��������������������������������������������������P999 Raj, Nitin ���������������������������������������������������������P1077 Rajagopalan, Vanishree �����������������������������������P279

Raje, Himanshu S. �����������������������������������������P1223 Rajeeve, Vinothini �������������������������������������������P1079 Rakusova, Hana ����������������������������������� P520,P2143 Ralston, Evelyn ����������������������������������������������P1798 Ramachandran, Rajesh ����������������������������������P1332 Ramachandra Rao, Sriganesh ������������������������� P511 Ramalingam, Nagendran �������������������������������P1323 Ramanathan, Saumya ��������������������������������������P292 Ramaraj, Pandurangan ���������������������������������� P1112 Ramasamy, Nivethitha ������������������������������������P1936 Ramel, Damien �����������������������������������������������P1433 Ramirez, Ana ��������������������������������������������������P2404 Ramirez, Robert ���������������������������������������������P1272 Ramírez-Aportela, Erney ��������������������������������P1787 RamirezCota, Rosa ������������������������������������������P970 Ramirez-Ricardo, Javier ���������������������������������P1440 Ramirez-SanJuan, Guillermina R. �������� P613,P2246 Ramond, Laurie ������������������������������������������������P915 Ramos, Mariona ���������������������������������������������P2099 Ramrattan, Girish �������������������������������������������P2422 Ramroop, Johnny �������������������������������������������P2422 Ramsay, Euan ��������������������������������������������������P884 Ramundo, Silvia ���������������������������������������������P2154 Rana, Manish �������������������������������������������������P1736 Rancati, Giulia I. ����������������������������������� P241,P1214 Randazzo, Davide ������������������������������������������P1798 Randolph, Clinita E. ����������������������������������������P1384 Rane, Hallie ����������������������������������������������������P1632 Rangamani, Padmini ���������������������������� P724,P2141 Rangan, Prashanth ������������������������������������������P759 Ranjan, Peeyush �������������������������������� P1830,P1831 Ranjan, Rajesh �������������������������������������������������P221 Rankin, Susannah ���������������������������������� P236,P239 Ranski, Alexandra H. ��������������������������������������P2064 Rao, Anand N. ��������������������������������������������������P974 Rao, Gadiparthi N. ����������������������������� P2206, P2275 Rao, Madan ������������������������������������������������������P937 Rao, Tejeshwar C. ������������������������������������������P2064 Raposo, Graça ������������������������������������� P499,P1288 Rasenick, Mark M. ��������������������������������������������P545 Rash, John E. �������������������������������������������������P2132 Raska, Ivan ����������������������������������������������������P1225 Raska, Otakar ������������������������������������������������P1225 Rasmussen, Jeffery P. ��������������������������������������P780 Rasmussen, Thomas E. ���������������������������������P1359 Rasoloson, Dominique �������������������������������������P472 Rasouli, Seyed J. �������������������������������������������P1577 Rathbun, Lindsay I. ��������������������������� P1548, P1859 Ratheesh, Aparna �������������������������������������������P1438 Raught, Brian ���������������������������������������������������P321 Rauniyar, Navin ����������������������������������������������P1823 Rausova, Petra �����������������������������������������������P1998 Raut, PawanKumar ������������������� P688,P2328,P2454 Ravasio, Andrea ���������������������������������������������P1471 Ravida, Nigel A. ������������������������������������������������P220 Ravinarayanan, Haribalaganesh ��������������������P1936 Ray, Ann ���������������������������������������������������������P2414 Ray, Anne-Marie ���������������������������������������������P2187 Ray, Anuttoma ��������������������������������������������������P630 Raychaudhuri, Urmimala ��������������������������������P1498 Rayermann, Glennis E. ������������������������������������P540 Rayermann, Scott ���������������������������������������������P540 Raymond, Anne-Aurélie ���������������������������������P1486 Razak, Khaleel �����������������������������������������������P1504 Razidlo, Gina ����������������������������������������������������P309 Reales-Rodriguez, Elena ���������������������������������P407 Rechs, Adam J. ������������������������������������������������P839 Reck-Peterson, Samara L. �����������������������������P1765 Rector, Dana ��������������������������������������������������P1292 Redd, Nadja �����������������������������������������������������P320 Redemann, Stefanie ����������������������������� P240,P1022 Redmond, Sarah B. ����������������� P1340,P1341,P2166 Redondo-Morata, Lorena �������������������������������P2094 Refai, Osama �������������������������������������������������P2130 Regisford, E. 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The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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G. ��������������������������������������������������P851 Reinhard, Sarah ���������������������������������������������P1504 Reinisch, Karin M. ���������������������������������� P535,P537 Reinsch, Sigrid S. �������������������������������������������P1544 Reis, Carlos R. �������������������������������������������������P394 Reisch, Paja ���������������������������������������������������P1658 ReisRamos, Jaqueline I. ����������������������������������P889 Reiter, Jeremy F. ��������������P148,P152,P1004,P1572 Reiterer, Veronika �������������������������������������������P1528 Remmelzwaal, Sanne ������������������������������������P2358 Remmert, Kirsten ����������������������� P955,P958, P1712 Ren, Bing ����������������������������������������������������������P203 Ren, He ����������������������������������������������������������P1213 Renda, Fioranna �����������������������������������������������P204 Renner, Derrick J. ���������������������������������������������P609 Rentala, Satyanarayana ������������������������P811,P1950 Rentzsch, Fabian ���������������������������������������������P152 Renvoise, Benoit ��������������������������������������������P1268 Renzaglia, Karen ����������������������������������������������P835 Repouliou, Anastasia ����������������������������������������P780 Retamal, Mauricio A. ��������������������������������������P2282 Reue, Karen ���������������������������������������������������P2392 Rexhepaj, Elton ����������������������������������������������P1034 Rexius-Hall, Megan ����������������������������������������P2390 Reyes, Celine ���������������������������������������������������P242 Reyes, Ciara C. ������������������������������������������������P640 Reynolds, Brent A. ������������������������������������������P1951 Reynoso Moreno, Eduardo ������������������������������P679 Reznikov, Leah R. ��������������������������������������������P147 Rhee, Sangmyung ������������������������������������������ P1159 Rhodes, Timothy 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AUTHOR INDEX Rivera-Perez, Luis M. �������������������������������������P1305 Rivero-Muller, Adolfo ����������������������������������������P628 Rizvanov, Albert ���������������������������������������������� P1116 Rizzotto, Andrea �����������������������������������������������P380 Ro, EunJi ��������������������������������������������������������P2448 Robb, Kevin P. ������������������������������������������������P2272 Roberson, Halona �������P1494,P1917,P1918,P1919, �������������������������������������������������������������������������� 1922 Robertis, Edward D. ���������������������������������������P1385 Roberts, Anthony J. ����������������������������������������P1774 Roberts, Melissa A. ����������������������������������������P1530 Roberts, Richard ����������������������������������������������P285 Roberts, Sally �������������������������������������������������P1244 Robertson, Eric �����������������������������������������������P1305 Robic, Julie �����������������������������������������������������P1354 Robins, Sean ��������������������������������������������������P1200 Robinson, Amanda �����������������������������������������P1502 Robinson, Carmie P. �����������������������������������������P888 Robinson, Douglas N. ����P962,P1707,P1861,P2164 Robinson, Jennilee B. ������������������������������������ P1611 Roca-Cusachs, Pere ������������������ P650,P655, P2284 Rocancourt, Murielle ��������������������������������������P1862 Rocha, Azucena J. �����������������������������������������P1876 Rockman, Matthew �����������������������������������������P1888 Rodal, Avital A. �����������������P397,P941,P1242,P1253 Rodriguez, Alexis J. ����������������������������������������P1727 Rodriguez, Fernando M. ���������������������������������P1230 Rodriguez, Joseph ����������������������������������������� P1176 Rodriguez, Peter �������������������������������� P1630,P2130 Rodríguez-Laureano, Lucelenie ���������������������P2136 Rodríguez-Monterrosas, Cecilia ��������������������� P1166 Rodriguez Pino, Marbelys ��������������������� P360, P447 Rodriguez Vásquez, Federico S. ����������������������P291 Roeder, Haley S. ����������������������������������������������P478 Roelants, Francoise M. ����������������������������������P2189 Rog, Ofer �������������������������������������������� P1871,P1874 Rogelj, Snezna �����������������������������������������������P1928 Rogers, Crystal D. ��������������������������������������������P762 Rogers, Edward M. �����������������������������������������P1558 Rogers, Gregory C. ������������������������������ P206,P1070 Rogers, Jason V. ��������������������������������������������P1298 Rogers, John C. ���������������������������������������������P1687 Rogers, Steve ���������������������������������������������������P621 Rogowski, Jacob ��������������������������������������������P1690 Rohani Larijani, Nazanin �������������������������������� P1163 Rohatgi, Rajat ��������������������������������������� P559,P1224 Rohena, Cristina C. ������������������������������������������P307 Roh-Johnson, Minna ����������������������������������������P326 Rohle, Dan �������������������������������������������������������P288 Rohrberg, Julia �����������������������������������������������P1957 Roig, Joan ��������������������������������������������������������P970 Rojas, Enrique R. �������������������������������������������P2217 Rojas-Fernandez, Alejandro ���������������������������P1532 Rokas, Antonis �����������������������������������������������P1499 Roldan Gutierrez, MariaLuisa ���������������������������P463 Rolfe, Mark �����������������������������������������������������P1916 Roll-Mecak, Antonina �������������������������������������P1786 Rolls, Melissa M. ������������������������������������ P976,P977 Roman, Beth ��������������������������������������������������P1428 Roman-Fernandez, Alvaro �������������������������������P318 RomanoSpica, Natalia ��������������������������������������P175 Romao, Maryse ������������������������������������������������P445 Romero Duenas, Barbara P. ���������������������������P2425 Romet-Lemonne, Guillaume ��������������������������P1862 Rompolas, Panteleimon ���������������������������������P2156 Ronan, Edward �����������������������������������������������P2227 Rongo, Christopher G. �������������������������������������P992 Ronjat, Michel �������������������������������������������������P1044 Roopra, Avtar ����������������������������������������������������P193 Roostalu, Johanna �����������������������������������������P1779 Roque, Serene �����������������������������������������������P2017 Ros, Robert ����������������������������������������������������P1696 Rosa, Adalberto L. . ��� P659, P814,P817,P818,P889 Rosa, Renata G. �����������������������������������������������P658 Rosa-Molinar., Eduardo ��������������������������������������P29 Rose, Amalia 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RosendoMercado, Nicole L. ���������������������������P1614 Rosenfeld, Steven S. �������������� P1102,P2233, P1753 Rosenfeld, Yuliya ����������������������������������������������P963 Rosenwald, Anne ��������������������������������� P831,P2075 Roskelley, Calvin D. ������������������������������������������P553 Ross, Owen ����������������������������������������������������P2158 Rosselli-Murai, Luciana K. ������������������������������P2096 Rossi, Guendalina ������������������������������������������P1264 Rossi, Nicholas A. ��������������������������������������������P864 Rossier, Olivier �����������������������������������������������P2280 Roth, Theresa ���������������������������������������������������P813 Rothbard, Nicholas �����������������������������������������P1200 Rothstein, Jeff �������������������������������������������������P2035 Rottner, Klemens �����������������P85,P2253, P93,P2084 Rougerie, Pablo ����������������������������������������������P2287 Roulson, Jo-an 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Russin, Michelle ���������������������������������������������P1983 Russo, Thatiane A. �����������������������������������������P2226 Rutherford, Erin L. ����������������������� P137,P138,P1808 Rutter, Jared ���������������������������������������������������P2387 Ruvolo, Sean P. ������������������������������������������������P172 Ruzicka, Josef ����������������������������������������������������P56 Ryan, Colm J. ������������������������������������������������� P1179 Ryan, Joel ������������������������������������������������������P2016 Ryan, Sean D. ������������������������������������������������P1057 Ryan, Sean �����������������������������������������������������P1850 Ryan, Weston �������������������������������������������������P1958 Ryler, Jessica �������������������������������������������������P2476 Ryniawec, John M. �����������������������������������������P1070 Ryu, Hyunryul ���������������������������������������������������P717 Ryu, Sung Ho 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Saad, Sara T. ������������������������������������������ P265,P658 Saad, Shady �����������������������������������������������������P710 Saarikangas, Juha �������������������������������� P539,P2268 Sabatini, David M. ��������������������������������������������P553 Sabatinos, Sarah A. ����������������� P1042,P1043,P1096 Sabblah, Thywill T����������������������������� .P1776, P1777 Sabino, Dora I. ����������������������������������������������� P1153

Sabnis, Amit ��������������������������������������������������� P1122 Sacher, Michael ������������������������������������������������P412 Sachse, Frank ������������������������������������������������P2462 Sachse, Martin �����������������������������������������������P2412 Sackett, Dan L. ����������������������������������� P1798,P1813 Sackrow, Marcus ��������������������������������������������P1658 Sadeghipour, Ehsan ���������������������������������������P2224 Sadikot, Takrima ����������������������������������������� P24,P25 Saeed, Mezida �������������������������������������������������P916 Saeki, Hiroshi �������������������������������������������������P1018 Saez, Tania �������������������������������������������������������P552 Safavian, Darya ����������������������������������������������P1845 Safran, Samuel �������������������������������������������������P953 Saga, Yusuke �������������������������������������������������P2466 Sagadevan, Addelynn ������������������������������������P2392 Saganti, Premkuma ������������������������������������������P284 Sagara, Hiroshi �����������������������������������������������P1559 Sagasti, Alvaro �������������������������� P780,P1713,P1714 Sagawa, Takashi ��������������������������������������������P1778 Sah, Jay Prakash �������������������������������������������P2479 Saha, Shambaditya ������������������������������������������P713 Saha, Sudeshna ���������������������������������������������P2069 Saha, Suvrajit ���������������������������������������������������P937 Sahai, Inderneel ���������������������������������������������P1336 Sahay, Shruti �������������������������������������������������� P1115 Saheki, Yasunori ������������������������������������� P537,P538 Sahgal, Pranshu �����������������������������������������������P402 Sahin, Gizem N. ���������������������������������������������P1553 Sahlgren, Cecilia ����������������������������������������������P628 Saiardi, Adolfo ������������������������������������������������P1598 Sailov, Talgat ��������������������������������������������������P1471 Saimani, Uma ������������������������������������� P1291,P2059 Sainlos, Matthieu �������������������������������� P2090,P2280 Saitakis, Michael ��������������������������������������������P2219 Saito, Kan �������������������������������������������������������P1956 Saito-Nakano, Yumiko ������������������������������������P2079 SaitoReis, Chelsea A. ���������������������������������������P587 Saka, Yasushi �������������������������������������������������P1480 Sakai, Tsuyoshi �������������������������������������������������P956 Sakamaki, Yuriko ��������������������������������������������P2074 Sakamoto, Kazuhiro ���������������������������������������P1559 Sakamoto, Kazuho �����������������������������������������P2192 Sakhichand, Ashley ������������������������������������������P534 Sala, Roberta �������������������������������������������������P1077 Salapaka, Murti V. ��������������������������������������������P125 Salas, Pedro J. �������������������������������������������������P456 Salazar, Eduardo P. ����������������� P1166,P1440,P1477 Salazar, Katterine A���������.P514, P672,P1007,P2114 Salceda, Rocio �����������������������������������������������P1412 Saldias, MariaPaz ������������������������������ P1437,P2307 Saldivia, Natalia ���������������������������������������������� P2114 Sale, Winfield S. ���������������������� P1001,P1002,P1012 Salehi-Ashtiani, Kourosh ��������������������������������P1927 Salgueiro, Alessandra M. ���������������������������������P313 Sali, Andrej �������������������������������������������������������P972 Saliceti-Piazza, Lorenzo ���������������������������������������P3 Salih, Maysoon ������������������������������������ P686, P2475 Salinas, Andrea ������������������������������������������������P290 Salinas, M. E. �������������������������������������������������P2427 Salis, Pauline ����������������������������������������������������P451 Sallee, Maria D. ������������������������������������������������P991 Salmon, Edward D. ����������������������������������������P1899 Salmon, Kelly R. �����������������������������������������������P231 Salmon, Wendy C. ��������������������������������������������P167 Salo, Tuula �����������������������������������������������������P2297 Salomaa, Siiri �����������������������������������������������������P73 Salomon, Dor �������������������������������������������������P2414 Salomon-Kent, Ronit ��������������������������������������P1668 Salort, Delphine ������������������������������������������������P445 Salot, Shimul �������������������������������������������������� P1115 Saltel, Frederic ��������������������������������������� P95,P1486 SalvadorMoreno, Naike ����������������������������������P1236 Samejima, Itaru ������������������������������������ P235,P1065 Sampat, Keerthika ������������������������������������������ P1103 Sample, Vedangi ����������������������������������������������P591 Sams, Clarence F. ������������������������������������������P2238 Samson, Brent ��������������������������������������������������P868 Samson, Edward B. ��������������������������������������������P96 Samwer, Matthias ���������������������������������������������P226 Sanchez, Evelyn S. ���������������������������������������� P1106 Sanchez, Gladis ���������������������������������������������P1832 Sanchez, Johan ����������������������������������������������P2469 Sanchez, Lili �����������������������������������������������������P290 Sanchez, Mario ����������������������������������������������P1366

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Sanchez, Pedro ����������������������������������������������P1054 Sánchez, Fabiola A. ���������������������������������������P1262 Sánchez Alvarado, Alejandro ������������� P2389,P2420 Sánchez-Huertas, Carlos ���������������������������������P975 Sánchez-Pupo, Rafael E. ���������������������������������P430 Sanchez-Zavaleta, Minerva ����������������������������P1412 Sanders, Anna A. ���������������������������������� P978,P1840 Sanders, Joseph ����������������������������������������������P601 Sandhu, Gurveen ������������������������������������������� P1133 Sandilands, Emma �������������������������������������������P318 Sandin, Sara ���������������������������������������������������P1600 Sandoval, Ariana M. ���������������������������������������P1231 Sandoval, Lisette ��������������������������������������������P1262 Sandoval, Melissa ������������������������������������������P1589 Sanes, Joshua R. �������������������������������������������P1570 Sanglard, Dominique ����������������������������������������P542 Sankaralingam, Prabhu ������������������������������������P205 San Martin, Alejandra ��������������������������� P527,P2107 San Martín, Rody E. �������������������������� P1985, P2185 Sano, Shoei ����������������������������������������������������P2301 Sansam, Christopher L. ����������������������������������P2005 SantanaRivera, Yasmarie �������������������������������P1945 Sant’Anna, Osvaldo A. �����������������������������������P2459 Santella, Anthony �����������������������������������������������P44 Santella, Regina M. ����������������������������������������P1961 Santiago, Ginette ��������������������������������������������P1969 Santiago-Tirado, Felipe H. ������������������������������P2423 Santisteban, Maria S. ������������������������������� P27,P853 Santos, Bianca �����������������������������������������������P2449 Santos, Gabriela P. �������������������������������������������P658 Santos, Marco ������������������������������������������������P1678 Santy, Lorraine C. �������������������������������������������P1248 Sapkota, Hem ���������������������������������������������������P230 Sapkota, Mahesh �������������������������������������������P1579 Saporita, Anthony �������������������������������������������P2183 Sarac, Radmila ���������������������������������������������������P23 Sarin, Sumeet �������������������������������������������������P1570 Sarkar, Saswata S. ����������������������� P942, P943,P944 Sarkar, Sourav ������������������������������������������������P2089 Sarker, Muzaddid ���������������������������������������������P909 Sarraf, Shireen A. �������������������������������������������P2315 Sarsam, Reta ���������������������������������������������������P550 Sasaki, Hideki ����������������������������������������� P872,P873 Sasaki, Mitsuho ������������������������������������������������P758 Sasser, Terry ���������������������������������������������������P1278 Satake, Tomoko ������������������������������������������������P490 Sathe, Aneesh R. ���������������������������������������������P608 Sato, Masamitsu ���������������������������������������������P1073 Sato, Yasufumi �������������������������������������������������P383 Sato, Yuko ������������������������������������������������������P2008 Satoh, Ayano ����������������������������������������������������P510 Satoh, Kimihiko ����������������������������������������������P1625 Satoskar, Abhay ���������������������������������������������P2426 Satpute-Krishnan, Prasanna ��������������������������P1519 Sauane, Moira ��������������������������������������������������P262 Saul, Naledi ������������������������������������������������������P848 Saunders, Cosmo A. ����������������������������������������P377 Saunier, Sophie ����������������������������������������������P1839 Saurabh, Saumya ������������������������������ P1663, P1672 Sauvageau, Etiene �����������������������������������������P1286 Savai, Rajkumar �����������������������������������������������P257 Savchenko, Alexei ������������������������������������������P1280 Sawaguchi, Akira ��������������������������������������������P1249 Sawaki, Yujin ����������������������������������������������������P537 Sawano, Maki �������������������������������������������������P1703 Sawant, Ketki �������������������������������������������������P1433 Sawant, Tanvee ����������������������������������������������P2435 Saway, Brian F. �����������������������������������������������P1800 Sawaya, Andrew P. �������������������������������������������P578 Sawicka, Anna ������������������������������������������������P2220 Sawyer, Eric M. ���������������������������������� P1215,P1344 Saxena, Manoj �����������������������������������������������P1943 Saxena, Sandeep �������������������������������������������P2244 Saxton, Michael J. ��������������������������������������������P720 Sayaman, Rosalyn �����������������������������������������P2300 Sayarova, Regina ������������������������������������������� P1116 Scales, Suzie J. ������������������������������������������������P999 Scarbrough, Chasity ���������������������������������������P1003 Scarfone, Ilaria �����������������������������������������������P1710 Scarlata, Suzanne ������������������������������������������P2141 Scarpati, Michael ��������������������������������������������P2422 Schadzek, Patrik ����������������������������������������������P633 Schaedel, Laura �����������������������������������������������P129

Schaefer, Antje �����������������������������������������������P1454 Schaefer, Jasmin ��������������������������������������������P1510 Schaeffer, Erik ������������������������������������������������P1801 Schaffer, David �������������������������������������������������P571 Schaffer, Miroslava �����������������������������������������P2091 Schaffner-Reckinger, Elisabeth ����������������������P1719 Scharaw, Sandra ��������������������������������������������P2092 Scharler, Cornelia ������������������������������������������� P1168 Schauder, Curtis M. ������������������������������������������P537 Schauer, Kristine ���������������������������������� P500,P1756 Schechtman, Deborah ������������������������������������P1401 Schedl, Andreas ���������������������������������������������P2476 Schedl, Paul �����������������������������������������������������P213 Scheidel, Noémie �������������������������������������������P1841 Schejter, Eyal D. ��������������������������������� P1470,P2363 Schekman, Randy W. ..........P354,P428,P429,P516, ............................................................... P1285,P431 Schelhaas, Mario ����������������������������������������������P947 Schellenberger, Pascale ���������������������������������P2097 Schellhaus, AnnaKatharina ����������������������������P1801 Schermer, Bernhard ���������������������������������������P1005 Scheuring, Simon �������������������������������������������P2094 Schevzov, Galina ��������������������������������������������P1976 Schibler, Andria C. ������������������������������������������P1217 Schiebel, Elmar ���������������������������������������� P98,P210 Schieber, Nicole L�������������������������������������� .P33, P34 Schiffhauer, Eric S. ������������������������������� P962 P1707 Schink, Kay O. ��������������������������������������������������P404 Schirmer, Eric ��������������������������������������� P380,P2029 Schlaepfer, David D. �����������������������������������������P657 Schlaitz, Anne-Lore ����������������������������������������P1015 Schleiffer, Alexander ���������������������������������������P1990 Schlesinger, Felix ���������������������������������������������P890 Schliep, Jan E. �����������������������������������������������P1666 Schlingmann, Barbara L. ����������������������������������P260 Schlosser, Florian �������������������������������������������P2223 Schluter, Melissa ���������������������������������� P858,P2183 Schmalhorst, Philipp S. ������������������������������������P226 Schmeichel, Karen L. ����������������������������� P834,P841 Schmid, Eva M. ������������������������������������������������P588 Schmid, Fabian ������������������������������������������������P146 Schmid, Sandra L. �������������������������������� P394,P1243 Schmider, Angela B. ���������������������������������������P1363 Schmidt, Broder ����������������������������������������������P1224 Schmidt, Christoph F. ����������������� P2223, P618,P964 Schmidt, Emily ������������������������������������������������P1701 Schmidt, Helen �������������������������������������������������P472 Schmidt, Jens ���������������������������������������������������P863 Schmidt, John A. ��������������������������������������������P1229 Schmidt, Sharol ������������������������������������������������P981 Schmidtke, Michael ����������������������������������������P2064 Schmidtmann, Elisabeth ���������������������������������P2016 Schmitt, Emmanuelle �������������������������������������P1979 Schmitt, Kristina �����������������������������������������������P629 Schmitthenner, Hans F. ���������������������������������� P1100 Schmoranzer, Jan ��������������������������������������������P988 Schnebert, Sylvianne ����������������������������������������������� �������������������������� P1628,P2310,P2402,P2403,P2443 Schneider, Ian C. ��������������������������������������������P2258 Schneider, Marie-Laure ������������������������������������P875 Schneider, Maximilian ��������������������������������������P226 Schneider, Robert J. ��������������������������� P1974,P1975 Schnell, Santiago ���������������������������������������������P390 Schoborg, Todd A. ������������������������������ P1070,P1573 Schöck, Frieder ������������������������������������ P914,P2361 Schoelz, James ����������������������������������������������P1626 Schoeneberg, Joh ������������������������������������������P2323 Schoffstall, Brenda ����������������������������� P1630,P2469 Schöls, Maximilian ������������������������������������������P1432 Scholz, Nicole ���������������������������������������������������P618 Schoor, Carmen ���������������������������������������������P2158 Schott, Sonia ��������������������������������������������������P1455 Schou, Kenneth B. ������������������������������� P146,P1839 Schrader, Timothy J. ��������������������������������������� P1186 Schreiber, John M. ������������������������������� P820,P2426 Schreiner, Sarah M. ����������������������������������������P1813 Schreurs, Ann-Sofie ���������������� P1953,P2324,P2333 Schrod, Nicholas ����������������������������������������������P400 Schroer, Trina A. ���������������������������������������������P1770 Schroth, Gary P. �����������������������������������������������P890 Schuamberg, Katherine A. �������������������������������P305 Schuchman, Ryan ������������������������������������������P1597 Schuh, Melina �������������������������������������������������P1030 Schuldiner, Maya ����������������������������������������������P408

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Schultheis, Martina �����������������������������������������P2371 Schultz, Richard M. ������������������������������ P249,P1063 Schulz, Olaf ����������������������������������������������������P1658 Schumacher, Linus �������������������������������������������P760 Schuman, Joel S. �������������������������������������������P2456 Schupbach, Gertrud M. ����������������������������������P1555 Schutten, Rutger ..................P507,P508,P623,P859, ............................................................. P1675,P1782 Schuyler, Scott C. �������������������������� P252,P253,P256 Schwab, Yannick ���������������������������������������� P33,P34 Schwaller, Juerg �����������������������������������������������P371 Schwarz, Ulrich S. ��������������������������������P611, P2231 Schwarz, Vera ��������������������������������������������������P947 Schwebach, Christopher ����������������������������������P896 Schweikhard, Volker �������������������������������������������P96 Schwille, Petra ��������������������������������������������������P730 Scoazec, Jean-Yves ��������������������������������������� P1153 Scorrano, Luca �����������������������������������������������P1325 Scott, Brandon L. ��������������������������������������������P2445 Scott, Phillip ������������������������������������������ P208,P1037 Scripture, Jared P. ������������������������������������������P1812 Scully, Jenna ��������������������������������������������������P1701 Scurll, Josh �������������������������������������������������������P933 Seabra, Miguel C. �������������������������������������������P1274 Sealfon, Stuart C. �������������������������������������������P1545 Sears, Jonathan E. �����������������������������������������P1648 Searson, Peter ����������������������������������������������� P1137 Sebastian, Aswathy ����������������������������������������P2393 Seddiki, Rima ���������������������������������������������������P445 Sedivy, Laura J. ����������������������������������������������P1397 Sée, Violaine �������������������������������������������������� P1103 Seebold, Dylan Y. ���������������������������������������������P976 Seemann, Joachim �����������������������������������������P1880 Segal, Dagan ��������������������������������������������������P1470 Segal, David J. �������������������������������������������������P884 Segarra, Veronica A. �������������������������������� P1,P1290 Segura-Bayona, Sandra ���������������������������������P2002 Segura-Valdez, Maria L. ���������������������������������P1234 Sehgal, Poonam ���������������������������������������������P1476 Sehgal, Pravin B. ����������������������������������������������P504 Sehgal, Ravinder ��������������������������������������������P1613 Sehlaoui, Ayoub ����������������������������������������������P1942 Seidel, Chris ��������������������������������������� P2389,P2420 Seifert, Michael �����������������������������������������������P1432 Seiler, Cynthia ������������������������������������������������P1463 Seira, Oscar �����������������������������������������������������P884 Sekine, Sayaka ����������������������������������������������P1677 Sekiya, Takao �������������������������������������������������P1559 Selassie, Cynthia ����������������������������������������������P852 Seldin, Lindsey �����������������������������������������������P1973 Selkoe, Dennis J. �������������������������������������������P1323 Seller, Charles A. ��������������������������������������������P1551 Sellers, James R. ����������������������������������� P952,P965 Sellers, Samantha S. ��������������������������������������P1492 Selzer, Evan B. �����������������������������������������������P1062 Sen, Buer ���������������������������������������������������������P373 Senbanjo, Linda T. ������������������������������ P1948,P1972 Sengupta, Kheya ����������������������������������������������P929 Sengupta, Prabuddha ������������������������������������P1665 Sengupta, Shinjinee ��������������������������������������� P1115 Senju, Yosuke �������������������������������������������������P2268 Seno, Masaharu ���������������������������������������������P1946 Seo, Arnold Y. �������������������������������������������������P2325 Seo, Brandon ������������������������������������� P1690,P2288 Seo, Bum-Ju ���������������������������������������������������P1644 Seo, Jong Bae ������������������������������������������������P1410 Seo, MinJi �������������������������������������������������������P1095 Seo, Young-Kyo ���������������������������������������������� P1129 Seok, Jin ���������������������������������������������������������P1435 Seong, Min-Ki �������������������������������������������������P1937 Sept, David S. ��������������������������������������������������P132 Serafini, Annalisa ��������������������������������������������P1325 Serebryakova, Marina V. ��������������������������������P1488 Sergi, Consolato �����������������������������������������������P316 Serikbaeva, Anara S. ����������������������������������������P133 Sermeno, Jasmyne ����������������������������������������P1502 Sero, Julia E. ����������������������������������������������������P605 Serra Lleti, José Miguel ����������������������������� P33, P34 Serrano, Ricardo ���������������������������������� P729,P2214 Serrano-Lachapel, Ivana ��������������������������������P1521 Serwas, Daniel �����������������������������������������������P1824 Seshadrinathan, Suchithra �����������������������������P1898 Sessions, Ayla O. ���������������������������������������������P664 Setou, Mitsutoshi ��������������������������������������������P1383

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AUTHOR INDEX Seum, Carole �������������������������������������������������P1803 Seveau, Stéphanie M. ������������������������������������P1733 Seydoux, Geraldine ������������������������������� P470, P472 Sfakis, Lauren M. ���������������������������������� P341, P761 Sgambato, Naiara ������������������������������������������P2287 Shackelton, Sue �����������������������������������������������P988 Shafer, Kyle ��������������������������������������������������������P78 Shah, Alok ��������������������������������������������������������P147 Shah, Arish N. ��������������������������������������������������P326 Shah, Devan ���������������������������������������������������P2355 Shah, Dilan S. ������������������������������������������������P1915 Shah, Hetal V. �������������������������������������������������P2315 Shah, Jagesh V. �����������������������������������������������P167 Shahar, Eyal �����������������������������������������������������P847 Shaheen, Ranad ������������������������������������������������P98 Shahi, Payam �������������������������������������������������P1964 Shahsavan, Hamed ����������������������������������������P1690 Shaik, Rahamthulla S. ������������������������������������P2153 Shaikh, Nadeem �����������������������������������������������P229 Shales, Michael ���������������������������������������������� P1179 Shaltiel, Indra A. �����������������������������������������������P233 Shami, Gerry ������������������������������������������������������P31 Shamir, Eliah R. �����������������������������������P1167,P1475 Shams, Hengameh ��������P603,P2034,P2230, P2228 Shang, Wenjun �����������������������������������������������P1654 Shankar, Jay ���������������������������������������� P321, P2244 Shao, Hanshuang �������������������������������������������P1415 Shao, Lin ������������������������������������� P87,P1429,P1712 Shapiro, Lucy �����������������P595,P1663,P1672,P2184 Shapiro, Paige ������������������������������������������������P1526 Shapiro, Steven D. �����������������������������������������P2164 Sharifkhodaei, Zohreh ��������������������������������������P638 Sharma, Ashwani ���������������������������������������������P139 Sharma, Cristian R. ����������������������������������������P2144 Sharma, Himanshu �����������������������������������������P1825 Sharma, Jay ���������������������������������������������������P2144 Sharma, Komal �����������������������������������������������P1831 Sharma, Mahak ���������������������������������� P1254,P2076 Sharma, Michael R. ����������������������������������������P2144 Sharma, Rohit ������������������������������������������������P1943 Sharma, Shweta ���������������������������������������������P1943 Sharma, Sonali �����������������������������������������������P1090 Sharma, Ved P. �������������������������������������������������P601 Sharp, Andrew A. ������������������������������������������������P70 Sharp, David J. ������������������������������������� P204,P1802 Shaw, Sidney L. �������������������������������������� P982,P984 Shawky, Joseph H. �������������������������������������������P767 Shay, Ashley E. ���������������������������������� P1640, P2418 Shea, Allyson E. ���������������������������������������������P1255 Shebelut, Conrad W. ����������������������������������������P213 Sheen, Duke �����������������������������������������������������P933 Sheen, Patricia �����������������������������������������������P1678 Sheetz, Michael P. ��������������������������������������������P608 Sheikh, Farah ������������������������������������� P2266,P2283 Sheikh, Nadeem ���������������������������������������������P2442 Shelanski, Michael L. ���������������������������������������P493 Sheldon, Kely ���������������������������������������������������P527 Shelley, Michael J. �����������P240,P1016, P245,P1878 Shelton, Alexis S. �������������������������������������������P1966 Shelton, Andrew �����������������������������������������������P934 Sheltzer, Jason ����������������������������������������������� P1114 Shen, Hongying ����������������������������������������������P1346 Shen, Kang ���������������������������������� P114,P485,P2362 Shen, Rongkun �����������������������������������������������P2209 Shen, Wen ������������������������������������������������������P1240 Shendure, Jay ������������������������������������������������P2481 Shenk, Thomas E. ��������������������������������������������P572 Shepchelovich, Jeanna ������������������������������������P415 Shepherd, Matthew ������������������������������������������P803 Sherer, Nathan M. ������������������������������ P1602,P1634 Sheridan, Paul ������������������������������������������������P1660 Sherlekar, Aparna ���������������������������������������������P936 Sherman, Shachar �����������������������������������������P1834 Sherr, Charles J. ���������������������������������������������P1963 Sherratt, David �����������������������������������������������P2003 Sherry, Jessica �����������������������������������P2410, P2411 Sherwood, David R. �����������������������������������������P653 Shew, Chwen Y. ������������������������������������������������P722 Shewan, Annette �������������������������������������������� P1133 Shi, Guey-Yueh ����������������������������������������������P1483 Shi, Liang ������������������������������� P1313, P1324,P1855 Shi, Xiaoyu �����������������������������������������������������P1004 Shi, Yu ��������������������������������������������������������������P443 Shi, Yufeng �����������������������������������������������������P1955

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Shiau, Andrew K. ��������������������������������������������P1038 Shiayama, Masaki ��������������������������������������������P173 Shibata, Kumiko ���������������������������������������������P2079 Shigematsu, Hideki ����������������������������������������P1750 Shih, Sheng-Min ���������������������������������������������P1814 Shilatifard, Ali ��������������������������������������������������P1963 Shilo, Ben-Zion ����������������������������������� P1470,P2363 Shim, Kyuhwan ������������������������������������ P155,P1826 Shima, Tomohiro �����������������������������������������������P144 Shimada, Issei ������������������������������������������������P1828 Shimada, Takahiro ������������������������������������������P2466 Shimamoto, Yuta ��������������������������������������������P1996 Shimazaki, Shunta �������������������������������������������P525 Shimizu, Kengo ������������������������������������������������P826 Shimizu, Miho �������������������������������������������������P2301 Shin, Hyejin ����������������������������������������������������P1603 Shin, Hye-Won �����������������������������������������������P1360 Shin, John J. ���������������������������������������������������P2056 Shin, Joo-Ho ���������������������������������������������������P2467 Shin, Kyeong Jin �������������������������������������������� P1129 Shin, Min-Kyung ���������������������� P2430,P2431,P2432 Shin, Seol H. ��������������������������������������������������P1094 Shin, William ���������������������������������������������������P2249 Shin, YongCheol ���������������������������������������������P2335 Shin, Yongdae ������������������������������������������������P1697 Shin, Yourim ���������������������������������������������������P1938 Shinichiro, Kokubun ���������������������������������������P1655 Shinogle-Decker, Heather ����������������������������������P29 Shinohara, Kyoko �������������������������������������������P2152 Shinohara, Yasuo ��������������������������������P1196,P1339 Shioi, Toru �������������������������������������������������������P1459 Shirai, Yasuhito ����������������������������������� P2180,P2473 Shiraki, Yuzuha �����������������������������������������������P1304 Shirasawa, Nobuyuki ��������������������������������������P1652 Shirasu-Hiza, Mimi �������������������������������� P168, P175 Shirazi-fard, Yasaman ������������������������ P2324,P2333 Shirnekhi, Hazheen K. ������������������������������������P1055 Shitara, Akiko �������������������������������������������������P1452 Shivakumar, Pruthvi C. �������������������������������������P763 Shivashankar, G.V. �������������������������������������������P608 Shokhirev, Max �����������������������������������������������P1218 Shorn, Olga ������������������������������������������������������P415 Shoshani, Liora ������������������������������������������������P463 Shoshani, Ofer �������������������������������������������������P203 Shrestha, Aastha ����������������������� P688,P2328,P2454 Shrestha, Sanjay ��������������������������������������������P1764 Shroff, Hari �������������������������������������������� P44, P1364 Shu, Huidy ������������������������������������������������������ P2311 Shu, Shi ������������������������������������������������������������P965 Shu, Xiaokun ������������������������������������������������������P51 Shu, Yun-Yan ��������������������������������������������������P1483 Shuai, Lina �����������������������������������������������������P1654 Shubeita, George T. ������������������������������������������P124 Shukla, Manu �������������������������������������������������P1995 Shulist, Kristy ��������������������������������������������������P1036 Shupe, John �����������������������������������������������������P313 Shurtleff, Matthew J. �����������������������������������������P354 Shuto, Tsuyoshi ���������������������������������� P2338,P2429 Shvartsman, Stanislav Y. ��������������������������������P1555 Sibarita, Jean-Baptiste �������������������������� P36, P2280 Sica, Gabriel �����������������������������������������������������P313 Sickler, Paxton S. ������������������������������������� P10,P837 Sideris, Dionisia P. ������������������������������� P531, P2159 Sidhaye, Ramana �������������������������������������������P2164 Siefert, Joseph C. �������������������������������������������P2005 Siekhaus, Daria ����������������������������������������������P1438 Siemers, Kathy A. ������������������������������� P1466,P1467 Sierra Potchanant, Elizabeth A. ������������������������P217 Siessere, Selma �����������������������������������������������P817 Sihto, Harri �������������������������������������������������������P315 Sikkel, Paul C. ������������������������������������������������ P1611 Sil, Anita ��������������������������������������������� P2078,P2419 Silkworth, William T. ������������������������������������������P102 Siller, Saul S. ��������������������������������������������������P1825 Silva, Alonso ���������������������������������������������������P2307 Silva, Heitor F. ��������������������������������������������������P818 Silva, Ian ���������������������������������������������������������P1437 Silva, Juliete F. �����������������������������������������������P2459 Silva, Luciane M. ��������������������������������������������P1832 Silva, Malan ������������������������������������������������������P992 Silva, Suély V. ��������������������������������������P1149,P1165 Silva-Alvarez, Carmen ������������������������������������ P2114 Silvander, Jonas S. �����������������������������������������P1330 Silveira, Linda A. ���������������������������������������������P2341

Silvestri, Cris �����������������������������������������������������P727 Silvestri, Nicholas �������������������������������������������P2172 Silvestri, Vanesa L. ����������������������������������������� P1137 Sim, Janice �����������������������������������������������������P1907 Sim, JooYong ������������������������� P1466,P1467, P1695 Sim, Shannon �������������������������������������������������P1023 Simmons, Ryan ������������������������������������������������P179 Simões, Gustavo F. ����������������������������������������P1505 Simon, Hans-GeorgSimon �����������������������������P1582 Simon, Layla �����������������������������������������������������P552 Simon, Mariella T. �������������������������������������������P1336 Simon, Matt ������������������������������������������������������P746 Simonds, William F. ������������������������������������������P301 Simone, Avital ��������������������������������������������������� P911 Simpson, Cory L. ��������������������������������������������P2156 Simpson, Elizabeth M. ������������������������������������ P2113 Sims, Brian �����������������������������������������������������P2348 Sing, Cierra N. ������������������������������������������������P1749 Singer, Robert H. ����������������������������������������������P356 Singh, Bhupendra ������������������������������������������� P1132 Singh, Jaskirat ��������������������������������������������������P999 Singh, Keshav ������������������������������������������������ P1132 Singh, Mahipal ��������������������������������������������������P879 Singh, Maneet ������������������������������������������������P1279 Singh, Pali P. ������������������������������������������������������P46 Singh, Puja �������������������������������������������������������P145 Singh, Pushpendra �����������������������������������������P2102 Singh, Rajesh K. �������������������������������������������������P94 Singh, Sandeep ����������������������������������������������P1627 Singh, Shaleni ������������������������������������ P1631,P1633 Singh, Shaneen ����������������������������������������������P2422 Singha, Bipradeb ����������������������������������������������P266 Singh Monga, Satdarshan P. ��������������������������P2106 Sinha, Bidisha ������������������������������������������������P2236 Siomi, Mikiko C. ������������������������������������������������P857 Sipieter, Francois �������������������������������� P1480,P2190 Sipione, Simonetta �����������������������������������������P2457 Sircy, Linda M. ������������������������������������������������P2417 Sirisaengtaksin, Natalie ����������������������������������P1258 Sirka, Katarina ������������������������������������������������ P1167 Sirkis, Daniel W. �����������������������������������������������P428 Sisk, Jeanne M. ����������������������������������������������P1396 Sisson, Joseph �����������������������������������������������P1003 Sitron, Cole S. ������������������������������������������������P1520 Sivakumar, Gayathri ���������������������������������������P2194 Sivamani, Raja �����������������������������������������������P1633 Sivaramakrishnan, Sivaraj ������������������������������P1745 Sixt, Michael �������������������������������������������������������P85 Sjöqvist, Marika ������������������������������������������������P628 Skabelund, Andrew J. �������������������������������������P1688 Skantz, Noah ��������������������������������������������������P1013 Skau, Colleen T. �����������������������������������������������P917 Skidmore, Mike �����������������������������������������������P1544 Skinkle, Allison ��������������������������������������� P541,P543 Skogs, Marie ���������������������P507,P508,P623,P1675, �������������������������������������������������������������P1128,P1782 Skokan, Taylor D. ���������������������������������������������P986 Skop, Ahna R. ��������������������������������������������������P173 Skorobogata, Olga �������������������������������������������P433 Skuodas, Sydney �������������������������������������������P1557 Slabodnick, Mark M. �����������������������������������������P940 Slanchev, Krasimir ������������������������������������������P1432 Slattum, Gloria ��������������������������������������������������P320 Slavov, Nikolai �������������������������������������P1198,P1679 Slawson, Chad �����������������������������������������������P1368 Slep, Kevin C. ������������������������������������� P1070,P1800 Sliwa-Gonzalez, Andrzej ����������������������������������P539 Sloan, Erica K. ������������������������������������������������P1425 Sluder, Greenfield �������������������������������������������P1037 Sluka, James P. ����������������������������������������������P1653 Slykas, Frank ��������������������������������������������������P2188 Smart, Ashley D. �������������������������������������������������P69 Smertenko, Andrei ��������������������������������������������P981 Smigova, Jana ������������������������������������������������P1225 Smindak, Richard J. ���������������������������������������P2066 Smirnov, Andrey ��������������������������������������������� P1116 Smith, Adam �����������������������������������������������������P190 Smith, Alex �����������������������������������������������������P1479 Smith, Alexandra ��������������������������������������������P1210 Smith, Allison M. ���������������������������������������������P2318 Smith, Chad ������������������������������������������������������P869 Smith, Deanna ������������������������������������������������P1313 Smith, Elizabeth F. ��������������������������������������������P997 Smith, George M. �������������������������������������������P1783

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Smith, Gilbert H. �����������������������������������������������P782 Smith, Jaclyn ����������������������������������������������������P208 Smith, Jarrett ����������������������������������������������������P470 Smith, Jayson J. �����������������������������������������������P784 Smith, Kelli �����������������������������������������������������P2087 Smith, Kevin ���������������������������������������������������P1540 Smith, Kyle P. ���������������������������������������������������P517 Smith, Lauren �������������������������������������������������P1573 Smith, Lydia ���������������������������������������� P1552,P2350 Smith, Sarah E. ��������������������������������� P1075, P1843 Smith, Stephanie M. ���������������������������������������P1963 Smith, Timothy J. ����������������������������������������������P414 Smith, Yoav ������������������������������������������������������P338 Smothers, Jared ���������������������������������������������P2059 Smtih, Jean A. ��������������������������������������������������P446 Smucker, Bradley W. ��������������������������������������P1915 Smutny, Michael ���������������������������������������������P1438 Sneeggen, Marte ����������������������������������������������P404 Snell, William J. ���������������������������������� P1830,P1831 Sniadecki, Nathan J. ��������������������������������������P1449 Snider, Chloe E. ����������������������������������� P908,P1848 Snyder, Kyle L. �����������������������������������������������P2174 Snyder, Solomon H. ���������������������������������������P2327 Snyder-Cappione, Jennifer �����������������������������P1566 Soares, David �������������������������������������������������P2213 Soberman, Roy J. �������������������������������������������P1363 Sobota, Radoslaw M. ���������������������������������������P988 Sobu, Yuriko ����������������������������������������������������� P116 Soeda, Shou ���������������������������������������������������P1755 Soeur, Jeremie �����������������������������������������������P2302 Soh, Yunjo ������������������������������������������������������P1579 Sohal, Anokh ����������������������������������������������������P477 Soheilypour, Mohammad P486,P2032,P2033,P2034 Sohn, Mira ������������������������������������������������������P1362 Sohn, Sook-Young ������������������������������������������P1622 Sokac, Anna M. ������������������������������������ P902,P1852 Sokell, Emma �������������������������������������������������P1660 Sokolova, Olga S. ������������������������������������������� P1169 Solc, Petr ��������������������������������������������������������P1998 Soll, Lindsey ������������������������������������������� P398,P399 Solovyeva, Valeria ������������������������������������������ P1116 Solowska, Joanna M. �������������������������������������P1320 Solvik, Tina �����������������������������������������������������P2077 Somale, Desiana ����������������������������������������������P924 Somepalli, Rajiv ����������������������������������������������P1013 Somma, Maria P. ����������������������������������������������P204 Sommese, Ruth ����������������������������������������������P1745 Son, Hyeong-U ���������������������������������� P1644, P2433 Son, Susie ������������������������������������������������������P1388 Son, Youngsook ���� P461,P821,P823,P1443,P2380, ������������������������������������������������������������������������P2398 Sonawane, Mahendra S. ��������������������������������P2085 Soneral, Paula ������������������������������������������������P1662 Song, Chang-Hwa �������������������������������� P677,P2413 Song, Jia L. ������������������������������������������������ P2,P773 Song, Jiyao �����������������������������������������������������P1342 Song, KwangHoon �����������������������������������������P2446 Song, Ningning �����������������������������������������������P2376 Song, Si Y. ������������������������������������������������������P1094 Song, WooKeun ��������������������������������������������� P1159 Sonnenschein, Halie A. ����������������������������������P2188 Soriano, Eduardo ���������������������������������������������P975 Soriano, Ferdie �����������������������������������������������P1916 SorrellsSmith, Lisa �������������������������������������������P762 Soruco, Marcela M. ����������������������������������������P1673 Sotelo-Camero, Alfonso J. ������������������������������P2452 Soto, Kimberly ��������������������������������������������������P241 Soto, Laura �������������������������������������������������������P319 Sougakoff, Wladimir ���������������������������������������P1678 Soung, Allison �������������������������������������������������P1317 Souza, Glauco R. �������������������������������������������P1700 Souza, Luiz G. ��������������������������������������������������P817 Spalthoff, Christian �������������������������������������������P964 Spangenburg, Espen E. ���������������������������������P1715 Sparta, Breanne �����������������������������������������������P560 Spasic, Milos ����������������������������������������������������P822 Specht, Suzanne ��������������������������������������������P1827 Spector, David L. ����������������������������������������������P343 Speight, Pam ��������������������������������������������������P2039 Spencer, Sabrina L. ����������������������������������������P1049 Sperry, Ann O. ������������������������������������������������P1837 Spieler, Peter ����������������������������������������������������P963 Spies, Kelsey B. ���������������������������������������������P1662 Spiliotis, Elias T. ����������������������������������������������P1303

Spiller, Frances �����������������������������������������������P1066 Spitzer, Nadja ������������������������������������� P2404,P2405 Spracklen, Andrew J. ��������������������������������������P1558 Spriet, Corentin ����������������������������������������������P1480 Springer, Timothy A. ������������������������������ P646, P662 Spudich, James A. ����������������P942,P943,P944,P961 Squatrito, Massimo �������������������������������������������P288 Squirrell, Jayne �����������������������������������������������P1501 Squyres, Georgia R. �����������������������������������������P798 Srinivasan, Deepa ������������������������������ P1948,P1972 Srinivasan, Saipraveen ������������������������������������P394 Srinivasasainagendra, Vinodh ������������������������ P1132 Srivastava, Vasudha ���������������� P962, P1861, P2229 Stach-Machado, Dagmar R. ���������������������������P2459 Stadler, Charlotte ���� P507,P508,P623,P1227,P1675 Stahnke, Stephanie ����������������������������������������P2084 Stahnke, Stephanie ����������������������������������������P2253 Stainier, Didier ������������������������������������������������P1577 Stam, Samantha �����������������������������������������������P919 Stamov, Dimitar R. ������������������������������������������P2232 Stampfer, Martha ��������������������������������������������P2300 Stanley, Geoffrey M. ���������������������������������������P1681 Stanley, Mackinzie ������������������������������������������P2077 Stanny, Clauda �������������������������������������������������P849 Stanyte, Rugile �����������������������������������������������P1990 Starborg, Toby ������������������������������������������������P1265 Stark, Benjamin C. �������������������������������������������P912 Stark, Holger ��������������������������������������������������P1666 Stark, Jeremy P. ���������������������������������������������P2314 Starostina, Natalia G. �������������������������������������P1024 Starr, Daniel A. �������������������������������������������������P367 Starr, Matthew L. ��������������������������������������������P1278 Staton, Donna ������������������������������������������������P2144 Stauffer, Jimmy �����������������������������������������������P1827 Stavoe, Andrea K. ������������������������������������������P1300 St-Denis, Nicole ����������������������������������������������P1400 Stearns, Tim �������� P166,P987,P1039,P1072,P1077, ������������������������������������������������������������������������P2148 Steeg, Patricia S. ����������������������������������������������P917 Steemer, Cayla B. ������������������������������������������P1542 Steer, James ��������������������������������������������������P2155 Steeves, Marcie A. �����������������������������������������P1336 Stefana, Irina ����������������������������������������������������P339 Stefanutti, Marine ����������������������������� P1902 , P1904 Steffen, Anika �����������������������������������������������������P93 Stehbens, Samantha J. ����������������������������������P1442 Stein, Mary-Pat ���������������������������������������������������P18 Steinmetz, Michel ���������������������������������������������P139 Stender, Joshua D. �����������������������������������������P1038 Stenmark, Harald ���������������������������������������������P404 Stepanyants, Natalia ��������������������������������������P1332 Stephen, Manu �����������������������������������������������P1583 Stephens, David J. �����������������������������������������P1310 Stephens, Jeff ���������������������������������������������������P589 Stephenson, Rachel E. ������������������������� P635,P2367 Stepicheva, Nadezda A. �����������������������������������P773 Stepp, MaryAnn ����������������������������������������������P2265 Stepp, Willi ��������������������������������������������� P126,P963 Sterling, Noelle �����������������������������������������������P1783 Sterling, Sarah M. �������������������������������������������P1844 Sterling, Stephanie ����������������������������� P1387,P2352 Sternberg, Paul W. �������������������������������������������P888 Sternberg, Samuel H. ������������������������������������� P1180 Stevens, Michelle B. �����������������������������������������P298 Stewart, Emma R. ������������������������������������������P2043 Stewart-Ornstein, Jacob ����������������������P1084,P1175 Steyer, Anna M������������������������������������������� P33, P34 Stieg, Adam Z. ������������������������������������������������P2392 Stjepanovic, Goran �����������������������������������������P2316 Stock, Fabrice ��������������������������������������������������P865 Stocsits, Roman ���������������������������������������������P1990 Stoddard, Patrick R. ���������������������������������������P1724 Stoeber, Miriam ����������������������������������������������P2097 Stohr, Bradley A. ���������������������������������������������P2036 Stoiber, Marcus ����������������������������������������������P2300 Stoletov, Konstantin ������������������������������������������P316 Stolzenbach, Francisca ���������������������������������� P1181 Stone, David E. ������������������������������������������������P469 Stoops, Emily H. �����������������������������������������������P389 Storck, Austin S. �����������������������������������������������P864 Storrie, Brian ����������������������������������������������������P432 Stover, Alexander �������������������������������������������P1336 Stowers, Samuel R. ����������������� P1340,P1341,P2166 Stracker, Travis H. ������������������������������������������P2002

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Stradal, Theresia E. �������������P85,P93, P2084,P2253 Straight, Aaron F. �������������������������������� P1061,P2015 Stratiievska, Anastasiia ��������������������������������������P49 Stratton, Miranda ����������������������������������������������P987 Strauss-Soukup, Juliane K. ����������������������������P2416 Striz, Anneliese C. ��������������������������������������������P437 Stroebel, David �����������������������������������������������P1862 Strohecker, Anne ��������������������������������������������P1967 Strohmayer, Matthew ���������������������������������������P341 Strom, Amy R. ������������������������������������������������P1987 Strong, Nicole ���������������������������������������������������P841 Stroud, Robert M. �������������������������������������������P2081 Stroupe, Christopher ��������������������������������������P2053 Strunk, Dirk ����������������������������������������������������� P1168 Strunov, Anton ��������������������������������������������������P204 Strzelecka, Magdalena ������������������������� P197,P1015 St Sauveur, Valérie ����������������������������������������� P1194 Stubb, Aki ���������������������������������������������������������P647 Stubenvoll, Alexander ���������������������������������������P257 Stuckey, Morgan A. �������������������������������������������P634 Studer, Sean �����������������������������������������������������P431 Studer, Vincent ���������������������������������������������������P36 Stumpff, Jason K. �������������������������������������������P1901 Sturgill, David M. ����������������������������������������������P353 Styers, Melanie L. ���������������������������������������������P845 Stylianidou, Stella ���������������������������������������������P801 Su, Emily ��������������������������������������������������������P1000 Su, Jun-Han �������������������������������������� P1991, P1993 Su, Xiaolei ��������������������������������������������������������P931 Su, Xudong �����������������������������������������������������P2261 Suarez, Cristian ��������������������������������������������������P84 Suarez, Katherine �������������������������������������������P1616 Suárez-Arroyo, Ivette J. ����������� P1923,P1974,P1975 Subagyo, Agus �����������������������������������������������P1703 Sudhof, Thomas C. �����������������������������������������P1681 Sud’ina, Galina F. �������������������������������������������P1488 Sueoka, Kazuhisa ������������������������������������������P1703 Suetsugu, Shiro ����������������������������������������������P2138 Sugawa, Mitsuhiro ������������������������������������������P1836 Sugawara, Yumika ������������������������������������������P1490 Suggs, Kelsey ��������������������������������������������������P259 Sugrue, Richard J. ������������������������������������������P1600 Suh, EunKyung ����������������������������������P1105, P1944 Suh, Pann-Ghill �����������������������������������P1129,P2211 Suhail, Yasir ���������������������������������������������������� P1170 Suico, Mary A. ������������������������������������������������P2338 Suico, MaryAnn ����������������������������������������������P2429 Sulerud, Taylor ������������������������������������������������P1804 Sullenberger, Catherine ����������������������������������P1609 Sullivan, Beth A. ���������������������������������������������P2015 Sullivan, Devin P. ����� P507,P508,P623,P859,P1034, �������������������������� P1227,P1540,P1684,P1706,P1782 Sullivan, Patrick F. ������������������������������������������P1264 Sullivan, William ���������������������������������� P224, P1865 Sulzer, David ��������������������������������������������������P1323 Suman, Rakesh ����������������������������������������������P1098 Sumikawa, Kenji ���������������������������������������������P1326 Summerbell, Emily ������������������������������P1143,P1145 Summers, Matthew K. ������������������������������������P1960 Sumpton, David ����������������������������������������������P1720 Sun, Elizabeth W. ���������������������������������������������P535 Sun, Fanglin ���������������������������������������������������P2337 Sun, Haoxiu ����������������������������������������������������P1584 Sun, Hong ��������������������������������������������������������P410 Sun, Huiyun �������������������������������������������P304,P1183 Sun, Jianwei �����������������������������������������������������P893 Sun, Jiaxin ������������������������������������������������������ P1411 Sun, Mingzhai ���������������������������������������������������P189 Sun, Nina N. �����������������������������������������������������P307 Sun, Sean ������������������������������������������� P1496,P2020 Sun, Siyu ����������������������������������������������������������P736 Sun, Tianhui ������������������������������������������ P413, P980 Sun, Xiangming ������������������������������������������������P882 Sun, Xiaoyu 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AUTHOR INDEX Sundby, Lauren ����������������������������������������������P1013 Sundquist, Wesley I. ������������������������������� P496,P498 Sung, Bong Hwan ������������������������������������������P2256 Sung, Jongmin �������������������������������������������������P961 Sung, MinWoo ������������������������������������������������P2153 SunSun, Peng ������������������������������������������������ P1170 Sunyer, Raimon ������������������������������������ P655,P2284 Suomi, Fumi ���������������������������������������������������P1333 Supuran, Claudiu T. ������������������������������������������P321 Surcel, Alexandra �������������������������������������������P1707 Suresh, Subbulakshmi �����������������������������������P1209 Surma, Michal A. ������������������������������������ P537,P541 Surrey, Thomas ����������������������������������������������P1779 Surve, Chinmay R. ����������������������������������������� P1136 Surya, Vinay N. �����������������������������������������������P2254 Susanto, Olivia D. ������������������������������������������� P1147 Susor, Andrej ��������������������������������������������������P1047 Suter, Daniel M. ������������������������������������������������P478 Sutinen, Meeri ������������������������������������������������P2297 Suto, Kunihiro ���������������������������������������������������P876 Sutovsky, Peter �������������������������������������������������P755 Sutton, Joanna R. ���������������������������������������������P815 Sutton, Shirley C. ���������������������������������������������P942 Sutton, Shirley ��������������������������������������������������P944 Suzanne, Magali ���������������������������������������������P1455 Suzuki, Atsushi �������������������������������������������������P490 Suzuki, Aussie ������������������������������������������������P1899 Suzuki, Kenta ������������������������������������������������� P1107 Suzuki, Osamu �������������������������������������������������P758 Suzuki, Toshiharu ������������������������ P115,P116,P1304 Suzuki, Yasuhiro �����������������������������������������������P383 Swadi, Rasha R. ��������������������������������������������� P1103 Swain, Pamela ���������������������������������������������������P57 Swaminathan, Jyothishmathi ��������������������������P1945 Swaminathan, Padmapriya ��������������������������������P60 Swaminathan, Vinay �����������������������������������������P646 Swanson, Joel A. ��������������������������������������������P1277 Swartz, Melody ����������������������������������������������� P1158 Swartz, S. Z. �����������������������������������������������������P202 Swarup, Sharan ����������������������������������� P538, P1251 Swat, Maciej ���������������������������������������������������P1653 Swayampakula, Mridula �����������������������������������P321 Swayne, Leigh A. ����������������������������������������������P387 Sweetman, Abigail ��������������������������������������������P349 Sweezy-Schindler, Oliver �������������������������������P1020 Swenson, Joel M. �������������������������������������������P1987 Swiatek, Jani L. ����������������������������������������������P1229 Swider, Zac �����������������������������������������������������P1712 Swulius, Matthew T. ����������������������������������������P1851 Sydir, Emma ���������������������������������������������������P1674 Szaszi, Katalin ������������������������������������������������P2039 Szczurek, Aleksander �������������������������������������P1238 Szczylik, Cezary ���������������������������������������������P1954 Szelest, Oskar ������������������������������������������������P1238 Sztul, Elizabeth �������������������������������������������������P417 Szuba, Agata ���������������������������������������� P915,P1456 Szwedziak, Piotr �����������������������������������������������P795 Szymanski, Craig �����������������������������������������������P40 Szymborska, Anna B. �������������������������������������P1657

T

Ta, Linda �����������������������������������������������������������P999 Taboga, SebastiãoRoberto �����������������������������P1565 Tacchelly-Benites, Ofelia ����������������������������������P559 Tacdol, Dustin �������������������������������������������������P1925 Tadahira, Kazuko ����������������������������������������������P379 Tadlock, Lauri ���������������������������������������������������P812 Tadvalkar, Gauri ���������������������������������������������P2265 Tafelmeyer, Petra ���������������������������������������������P866 Tagawa, Masatoshi �������������������������������������������P409 Tagaya, Mitsuo ����������������������������������� P1350,P2052 Tagoe, Daniel �������������������������������������������������P2069 Taguchi, Akihiro ���������������������������������� P2463,P2466 Taguchi, Yumiko V. �������������������������������������������P400 Tahimic, Candice G. ���������������� P1953,P2324,P2333 Tai, Jung-Hsiang ���������������������������������������������P1284 Tain, You-Lin ���������������������������������������������������P2399 Takabayashi, Ryosuke �����������������������������������P1730 Takada, Masafumi ������������������������������������������P2338 Takada, Naoto ������������������������������������������������P1360 Takahashi, Ken ������������������������������������� P614,P2237 Takahashi, Masahide ����������������������������������������P787 Takahashi, Masaki ��������������������������������������������P826

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Takahashi, Naoto ��������������������������������������������P2181 Takahashi, Nobuyasu �������������������������������������P1249 Takahashi, Ryosuke ���������������������������������������P1703 Takahashi, Tomoyuki ��������������������������������������P1308 Takano, Tetsuya ����������������������������������������������P2195 Takashiba, Shogo �������������������������������������������P2237 Takatsu, Hiroyuki ��������������������������������������������P1360 Takayama, Jun �������������������������������������������������P744 Takayama, Kaori ���������������������������������������������P2313 Takayama, Kentaro ���������������������������� P2463,P2466 Takayanagi, Hiroshi ����������������������������������������P2155 Takeda, Shizu ���������������������������������������������������P876 Takeda, Yasuko ������������������������������������������������P352 Takei, Gen L. ��������������������������������������������������P1014 Takekawa, Mutsuhiro ��������������������������������������P1045 Takemaru, Ken-Ichi ����������������������������������������P1825 Takeuchi, Atsuko �������������������������������� P2180,P2473 Takiguchi, Kingo �����������������������������������������������P722 Takiguchi, Yoshiharu ��������������������������������������� P1196 Takshak, Anjneya ���������������������������������������������P715 Talhouk, Rabih S. ���������������������������������������������P631 Talsness, Dana M. ������������������������������������������P1798 Tamada, Masako ��������������������������������������������P1574 Tamasas, Basma ����������������������������������������������P778 Tamborlim, Letícia ������������������������������������������P1376 Tamura, Atshushi ������������������������������������ P641,P643 Tamura, Naoka �������������������������������������������������P229 Tamura, Sachiko ���������������������������������������������P1996 Tamura, Yasushi ���������������������������������������������P1342 Tan, Aik L. ���������������������������������������������������������P840 Tan, Hui Bing ������������������������������������������������������P79 Tan, Jiongyi ���������������������������������������� P1466,P1467 Tan, Li Xuan ���������������������������������������������������P1275 Tan, Piau S. ����������������������������������������������������P2050 Tan, Piau Siong ����������������������������������������������P1658 Tan, Ruensern ������������������������������������������������P1767 Tanaka, Masato ����������������������������������������������P1725 Tanaka, Ryosuke �������������������������������� P1459,P1703 Tanaka, Shoko ������������������������������������������������P2192 Tanaka, Shunsuke ��������������������������������������������P722 Tanaka, Toshiaki �����������������������������������������������P566 Tanaka, Yosuke ������������������������������������������������ P112 Tanaka-Takiguchi, Yohko ��������������������������������P1758 Tanasa, Bogdan ���������������������������������������������P1566 Tandon, Mayank �����������������������������������������������P576 Taneja, Nilay ���������������������������������������������������P1859 Tanenbaum, Marvin E. ���������������������������������������P61 Tanentzapf, Guy ����������������������������������� P649,P2385 Tang, Chih-Hang A. �������������������������������� P275,P708 Tang, Hao ���������������������������������������������������������P151 Tang, Hsin-Yao ���������������������������������������������������P97 Tang, Lu ����������������������������������������������������������P1959 Tang, Ming-Jer ���������������������������������������� P299,P616 Tang, Nan ���������������������������������������������������������P766 Tang, Sha �������������������������������������������������������P1336 Tang, Tang K. ����������������������������������������������������P209 Tang, Xiaohu ����������������������������������������������������P181 Tang, Yangzhong ��������������������������������������������P1916 Tang, Zan ���������������������������������������������������������P766 Tang, ZhaohuaIrene �����������������������������������������P359 Tani, Tomomi ����������������������������� P646,P1669,P1810 Taniguchi, Keiko �����������������������������������������������P261 Taniguchi, Yuichi ���������������������������������������������P2008 Tanimoto, Hirokazu ��������������������������������P445,P2115 Taniue, Kenzui ��������������������������������������������������P352 Tank, Damien G. �����������������������������������������������P244 Tanner, Bertrand C. ����������������������������������������P2471 Tanner, Jason M. ��������������������������������������������P2387 Tannert, Sebastian �����������������������������������������P1658 Tanouchi, Yu ������������������������������������������� P67,P1617 Tanowitz, Michael ���������������������������������������������P410 Tanter, Mickael �������������������������������������������������P812 Tao, Li ���������������������������������������������������P114, P1865 Tao, W. A. ���������������������������������������������������������P334 Tapia, Hugo ����������������������������������������� P696, P1518 Tarafder, Abul K. ���������������������������������������������P1274 Tarasenko, Daryna �������������������������������������������P521 Tardif, Nicolas ���������������������������������������������������P619 Tarkowski, Bartosz �������������������������������������������P475 Tarpey, Michael D. ������������������������������������������P1715 Tarren, Anna Y. �������������������������������������������������P551 Taskin, Ali C. ���������������������������������������������������P1553 Tassé, Louis-Alexandre A. ������������������ P1515,P1517 Tateishi, Kazuhiro ���������������������������������������������P641

Tavares, Edith B. ��������������������������������������������P1500 Taveneau, Cyntia ��������������������������������������������P1444 TavorRe’em, Tali �����������������������������������������������P336 Taya, Kazuyoshi �����������������������������������������������P753 Taye, Marta �����������������������������������������������������P1988 Taylor, Barry S. �������������������������������������������������P288 Taylor, Chris ����������������������������������������������������P1074 Taylor, James ���������������������������������������������������P884 Taylor, Kendra L. ����������������������������������������������P495 Taylor, Kevin �����������������������������������������������������P890 Taylor, Marcus J. ��������������������������������������������P2201 Taylor, Mark A. ��������������������������������������������������P846 Taylor, Russell ��������������������������������������������������P495 Taylor, Sean R. ����������������������������������� P1361,P2388 Taylor, Susan S. ���������������������������������������������P2186 Tchernyshyov, Irina �����������������������������������������P1861 Tedesco, Donato ��������������������������������������������P2458 Tee, Yee-Han ������������������������������������������ P918,P953 Tei, Freda F. ����������������������������������������������������P1607 Teixeira, Felipe R. �������������������������������������������P1401 Teixeira, Mariana B. ���������������������������������������� P1188 Teixido-Travesa, Neus ��������������������������������������P970 Teixiera, Luiz F. �����������������������������������������������P1931 Tellechea, AnaLuisa �����������������������������������������P665 Telley, Ivo A. ����������������������������������������������������P2346 Temoche-Diaz, Morayma M. ����������������������������P354 Tempes, Aleksandra �����������������������������������������P475 Tempst, Paul �����������������������������������������������������P288 Teng, Junlin ������������������������������������������������������P969 Terada, Hiroshi �����������������������������������������������P1339 Terahara, Yoko �������������������������������������������������P874 Termini, Christina M. ����������P520,P586, P587,P1171 Terrazas, César ����������������������������������������������P2426 Terry, Mary B. �������������������������������������������������P1961 Terry, Stephen J. ���������������������������������������������P1864 Teruel, Mary N�������������������P718,P785,P1643,P1527 Tervonen, Aapo ������������������������������������������������P637 Terzi, Fabiola ��������������������������������������������������P2203 Tessari, Isabella ������������������������������������������������P398 Tetkova, Anna �������������������������������������������������P1047 Tetlow, Ashley L. ���������������������������������������������P1822 Tetzlaff, Wolfram �����������������������������������������������P884 Tewari, Manorama ���������������������������������P600,P1141 Tewson, Paul H. ���������������������������������������������P2208 Thai, David G. ��������������������������������������������������P738 Thakar, Dhruv ������������������������������������������������� P1157 Thakar, Ketan �������������������������������������������������P1219 Thaker, Tarjani M. �������������������������������������������P1421 Thalheim, Tobias ������������������������������������������������P85 Thaller, David ��������������������������������������P1208,P1211 Thanabalu, Thirumaran ��������������������������������������P79 Thapa, Slesha ��������������������������������������������������P581 Tharmarajah, Grace �����������������������������������������P884 Thebault, Philippe �������������������������������������������P1909 Theesfeld, Chandra L. ������������������������������������P1545 Theriot, Julie A. ������ P622,P794,P913,P1239,P1615, ��������������������������������������P1619,P2214,P2407,P2409 Théry, Manuel ��������������������������������������� P129,P1710 Theurillat, Ilan �������������������������������������������������P1963 Thiagarajan, Visalatchi �������������������������������������P953 Thiam, Hawa R. �����������������P376,P917, P666,P1746 Thiex, Natalie W. �������������������������������� P1263,P2067 ThiThao, Dang ������������������������������������������������P1807 Thiyagarajan, Sathish ������������������������� P1853,P1854 Thomas, Anitha ������������������������������������������������P884 Thomas, Anthony ���������������������������������������������P479 Thomas, David D. ���������������������������������������������P473 Thomas, Dustin ����������������������������������������������P1707 Thomas, Laura �������������������������������������������������P444 Thomas, Miranda ����������������������������������P302,P1126 Thomas, Soweto ����������������������������������������������P810 Thomason, Peter A. ������������������� P105,P1147,P1979 Thomasy, Sara M. ������������������������������������������P1502 Thomley, Jill E. �������������������������������������������������P853 Thompson, OscarTh ���������������������������������������P1048 Thompson, Ryan ����������������������������������������������P862 Thompson, Will �������������������������������������������������P181 Thompson, Winston E. �����������������������������������P2163 Thompson-Peer, Katherine L. ������������������������P1319 Thoms, David ���������������������������������������������������P982 Thomsen, Nathan D. ������������������������������������������P69 Thorner, Jeremy W. ���������������������������� P1844,P2189 Thornton, Lauren ��������������������������������������������P1762 Thorsen, Kevin D. �������������������������������������������P1293

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Thoumine, Olivier �������������������������������������������P2280 Thul, Peter ���������������� P503,P507,P508,P623,P1782 Thurley, Kevin ���������������������������������������������������P617 Ti, Shih-Chieh �������������������������������������������������P1787 Tian, Dong ������������������������������������������������������P1857 Tian, Fuyun �����������������������������������������������������P2131 TilijaPun, Nirmala ��������������������� P688,P2328, P2454 Tillo, Shane E. ������������������������������������������������P2208 Tilly, Jonathan L. �����������������������������������������������P669 Timucin, Linda R. ��������������������������������������������P1544 Tindle, Courtney ���������������������������������������������P1280 Ting, Alice �������������������������������������������������������P1686 Tingey, Mark �����������������������������������������������������P349 Tinoco, Arthur D. ���������������������������������������������P1943 Tintori, Sophie ��������������������������������������������������P940 Tipan, Pablo �����������������������������������������������������P960 Tipton, Aaron R. ����������������������������������������������P1019 Tischer, Christian ������������������������������������������������P34 Tiwari, Hemant K. ������������������������������������������� P1132 Tkachenko, Eugene ���������������������������������������P2227 To, Milton ��������������������������������������������������������P1530 Tockner, Birgit ������������������������������������������������� P1168 Toda, Nick �������������������������������������������������������P1995 Todi, Sokol V. ����������������������������������������������������P815 Toettcher, Jared E. ���������P732,P1122,P1555,P1697 Toivola, Diana M. ��������������������������������������������P1330 Tojkander, Sari ������������������������������������������������P1980 Tok, Olgu E. ������������������������������������������������������P526 Tokunaga, Chihiro ������������������������������������������ P1107 Toledo, Jorge R. �����������������������������������������������P291 Tolic, Iva M. ������������������������������������������������������P186 Tolsma, Thomas O. ������������������������������������������P403 Tomaic, Vjekoslav �������������������������������������������P1244 Tomancak, Pavel ��������������������������������������������P2365 Tomic-Canic, Marjana ���������������������������������������P578 Tominaga, Nobuko ����������������������������������������� P1107 Tomschik, Miroslav �����������������������������������������P1884 Tomy, Meril �������������������������������������������������������P359 Tone, Shigenobu ��������������������������������������������P1725 Tong, Amy ������������������������������������������������������� P2311 Tong, Mian M. �������������������������������������������������P1637 Tong, Pin ��������������������������������������������������������P1995 Tonnesen, Marcia G. ��������������������������������������P1503 Tonozuka, Takashi ��������������������������������������������P379 Toops, Kimberly A. ������������������������������������������P1275 Tora, Muhibullah S. �����������������������������������������P1452 Torbati, Mehdi �������������������������������������������������P1220 Torchia, Enrique ���������������������������������������������P1958 Torello, Cristiane O. ������������������������������������������P265 Toret, Christopher P. �����������������������������������������P763 Torok-Storb, Beverly �����������������������������������������P788 Toropova, Katerina �����������������������������������������P1774 Torre, Paola ������������������������������������������������������P739 Torres, Angelo S. ��������������������������������������������P1985 Torres, Gloria ����������������������������������������������������P527 Torres, Marcos ��������������������������������������������������P860 Torres, Nayeli ���������������������������������������������������P674 Torres, Zally ���������������������������������������������������� P1113 Torta, Federico �������������������������������������������������P535 Toscani Field, Jasper ��������������������������������������P1613 Toseland, Christopher P. ������������������������� P946,P966 Toth, Peter ������������������������������������������������������P2390 Tóth, Dániel J. ������������������������������������������������P1416 Touaitahuata, Heiani ���������������������������������������P2248 Touissant, Terrence �������������������������������������������� P11 Toulmay, Alexandre ������������������������������������������P550 Tourdot, Richard ��������������������������������������������� P1161 Touret, Nicolas ��������������������������������������������������P593 Tournier, Sylvie �������������������������������������������������P242 Tower, John ���������������������������������������� P1512,P1523 Townsend, Alexandra �������������������������������������P1529 Toyama, Yusuke ���������������������������������������������P1471 Toyooka, Kazuhito ��������������������������������������������P491 Toyoshima, Yoko Y. �����������������������������������������P1836 Toyota, Rikako ��������������������������������������������������P510 Trakhanov, Sergei ������������������������������ P1666,P2031 Traktman, Paula ���������������������������������������������P1426 Tran, Luan ������������������������������������������������������P1953 Tran, Michelle D. ��������������������������������������������P1798 Tran, Pamela V. ����������������������������������������������P1832 Tran, Peter B. �������������������������������������������������P1544 Tran, Phong P. ������������������������������������������������P1073 Tran, Phuoc T. ������������������������������������������������P1765 Tran, Quan �����������������������������������������������������P2326

Tran, Thu ��������������������������������������������������������P1568 Tran, Tiffaney ��������������������������������������������������P2357 Tran, Trinh T. ��������������������������������������������������P2479 Trepat, Xavier ��������������������������������������� P604,P2284 Trepat, Xavier ���������������������������������������������������P655 Treutlein, Barbara �������������������������������������������P1681 Treyer, Aleksandr ��������������������������������������������P1295 Trimble, William S. ������������������������������������������P1845 Trinh, Gina ��������������������������������������������������������P910 Trinh, Le A. ���������������������������������������������������������P68 Trinkaus-Randall, Vickery ������������������� P2247,P2273 Trivedi, Vikas ������������������������������������������������������P68 Trivedi, Darshan V. �������������������������������������������P944 Trogden, Kathryn P. ������������������������������������������P979 Trokter, Martina 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�����������������������������������������������P1924 Tsai, Kelvin K. ������������������������������������������������� P1160 Tsai, Mu-shiun ��������������������������������������������������P687 Tsai, Pei-I ��������������������������������������������������������P2158 Tsai, Pei-Ju ����������������������������������������������������� P1135 Tsai, Wei-Wei ������������������������������������������ P252,P253 Tsao, David ���������������������������������������������������������P96 Tsao, Yeou-Ping ���������������������������������������������P2395 Tse, Sarah ��������������������������������������������������������P439 Tse, YuChung �������������������������������������� P183, P1212 Tseng, Hubert �������������������������������������������������P1700 Tseng, Pang-Yen �������������������������������������������� P1311 Tseng, Yiider ���������������������������������������������������P2261 Tseng, Ying-Ting ���������������������������������������������P1924 Tsopoulidis, Nikolaos 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�������������������������������������������������P917 Tuchina, Oksana P. ����������������������������������������P2381 Tucker, Diane C. �����������������������������������������������P844 Tudor, Sara �������������������������������������������������������P759 Tueros, Felipe G. ��������������������������������������������P2136 Tuli, Amit ����������������������������������������������P1123,P2076 Tulodziecka, Karolina ���������������������������������������P544 Tuma, Dean J. ������������������������������������������������P2063 Tuma, Pamela L. ����������������������� P437,P2062,P2063 Tumanov, Sergey ������������������������������������������� P1147 Tung, Yi-Chung �����������������������������������������������P1450 Tunggal, Ingrid ������������������������������������������������ P1133 Turchi, Laurent �����������������������������������������������P1985 Turnbull, Kira L. ������������������������������������������������P194 Turner, Carl �����������������������������������������������������P2464 Turner, Christopher E. ������������������������������������P1485 Turner, Lorianne S. ����������������������������������������� P1127 Turner, Meghan ������������������������������������������������P792 Turner, Zach ���������������������������������������������������P1013 Turpin, Chris �����������������������������������������������������P179 Turteltaub, Ken �������������������������������������������������P277 Tuszynski, Jack A. ������������������������������������������P1537 Tutak, Wojtek ��������������������������������������������������P2292 Tuttle, Adam ���������������������������������������������������P1413 Tutucci, Evelina ������������������������������������������������P356 Tuvim, Michael J. ��������������������������������������������P2065

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Tuzel, Erkan ������������������������������������������ P127, P728 Tvorogova, Anna ������������������������� P133,P134,P1087 Tweedy, Luke �������������������������������������������������� P1147 Tyagi, Swati ����������������������������������������������������P2050 Tynninen, Olli ����������������������������������������������������P315 Tyra, Lauren K. �����������������������������������������������P2321 Tyska, Matthew J. ��������������������������������� P954,P1859 Tyteca, Donatienne ����������������������������������������P1354

U

Ubieto-Capella, Patricia ����������������������������������P1051 Ubukawa, Kumi ����������������������������������������������P2181 Uchida, Yutaka �������������������������������������������������P949 Uchio-Yamada, Kozue ��������������������������������������P758 Uchiyama, Lauren F. ��������������������������������������P1328 Uddin, Mohammad M. ������������������� P266,P267,P273 Udey, Mark C. ���������������������������������������������������P639 Udgaonkar, Jayant B. ���������������������������������������P701 Udy, Dylan B. ���������������������������������������P1021,P1911 Ueda, Shuji ����������������������������������������� P2180,P2473 Uehlein, Lindsey �����������������������������������������������P179 Uemura, Sotaro ������������������������������������������������P857 Ueno, Tasuku ����������������������������������������������������P716 Uesugi, Yasuyuki ����������������������������������������������P482 Uetake, Yumi ��������������������������������������������������P1037 Ugarova, Tatiana P. ����������������������������������������P1696 Uhlemann, Eva E. ��������������������������������������������P173 Uhlén, Mathias P58,P507,P508,P623,P1034,P1128, ��� P1227,P1675,P1683,P1684,P1706,P1782,P2165 Uji, Masami ��������������������������������������������� P641,P643 Ukai, Hirofumi �������������������������������������������������P1392 Ullman, Katharine S. ����������������������������������������P496 Ulrich, Theresa A. �������������������������������������������P1951 Um, Da-eun ����������������������������������������������������P1514 Umbreit, Neil T. �����������������������������������������������P1897 Umehara, Takashi �������������������������������������������P2008 Umen, James G. ��������������������������������������������P2048 Umezu, Chiya �������������������������������������������������P1493 Ünal, Elçin ������������������������������������������ P1215,P1344 Underwood, Katherine ������������������������������������P2136 Ungar, Daniel ����������������������������������������������������P420 Uno, Midori �������������������������������������������������������P525 Unrau, David ���������������������������������������������� P33,P34 Unruh, Jay ������������������������������������������������������P1075 Unsal, Cem �������������������������������������������������������P728 Upadhyay, Maitreyi �������������������������������������������P759 Uppalapati, Chandana K. �������������������������������P2263 Urano, Takeshi ������������������������������������������������P1233 Urbach, Serge ������������������������������������������������P2248 Urban, Alexander ��������������������������������������������P1582 Urban, Joachim ����������������������������������������������P1994 Urban, John ������������������������������������������������������P201 Urbina, Fabio L. ����������������������������������������������P2054 Urlaub, Henning ���������������������������������������������P1666 Urrutia, Pamela ������������������������������������������������P434 Urs, Aarti N. ����������������������������������������������������P2123 Ursin, Rebecca �����������������������������������������������P2372 Usluer, Gulsima D. �������������������������������������������P799 Usuda, Kento ����������������������������������������������������P753 Usui, Takeo �����������������������������������������������������P2463 Usukura, Eiji �������������������������������������� P1671, P1716 Usukura, Jiro �������������������������������������� P1671,P1716 Uzer, Gunes �����������������������������������������������������P373 Uzun, Sercan ��������������������������������������������������P1921

V

Vaccaroli, Raffaella �����������������������������������������P1719 Vacher, Sophie �����������������������������������������������P1979 Vaden, Deirdre ����������������������������������������������������P28 Vafaeinik, Farzaneh ������������������������������������������P556 Vaghela, Malti �������������������������������������������������P1080 Vahey, Michael D. ���������������������������������������������P248 Vaidya, Kiran �������������������������������������������������� P1193 Vaidyanath, Arun ��������������������������������������������P1946 Vaidyanathan, Srividya �����������������������������������P1959 Vakiani, Evi �������������������������������������������������������P324 Valasek, Jan ���������������������������������������������������P1998 Valdebenito, Iván ����������������������������������������������P684 Valderrama, Juan D. ����������������������������� P406,P1621 Valdivia, Alejandra ����������������������������� P2107, P2173 Valdivia, Raphael H. ���������������������������������������P2410 Vale, Ronald D. ���P61,P596,P726,P802,P931,P961, ������������������������� P1766,P1781,P2168,P2204, P2201

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AUTHOR INDEX Valencia, Sara P. ��������������������������������������������P2080 Valent, Erik �������������������������������������������������������P668 Valenzuela, Guillermo E. ���������������������P1181,P1532 Valiullina, Aygul ����������������������������������������������� P1116 Valiyeva, Fatima ���������������������������������������������P1969 Valle, Eduardo ������������������������������������������������P1916 ValleAramburu, Iker ����������������������������������������P2050 Vallee, Richard B. ������������������������������ P1773, P1815 Vallejo, Marylou ������������������������������������������������P321 Valm, Alex M. ������������������������������������������������������P48 Valon, Léo ���������������������������������������������������������P604 Valtier, Sandra �������������������������������������P1187,P1688 Van, ThiNhuNgoc �������������������������������������������P2090 vanBezu, Jan ����������������������������������������������������P668 Vancini, Ricardo ����������������������������������������������P1597 Vancura, Ales ����������������������������������������������������P266 Vancurova, Ivana ��������������������������� P266,P267,P273 Vandenabeele, Peter ��������������������������������������P2190 vanden Berg, Jeroen ��������������������������������������P1040 vanden Broek, Bram ���������������������������������������P1040 vanden Broek, Niels ��������������������������������������� P1147 vander Does, Marit �����������������������������������������P2003 vander Meulen, Annelot I. �������������������������������P2001 Vanderpool, Kimberly G. ���������������������������������P2132 Vander Wende, Helen M. �������������������������������P1877 van Duijn, Trynette �����������������������������������������P1454 Van Eyk, Jennifer ��������������������������������������������P1861 van Galen, Josse ����������������������������������������������P416 van Haren, Jeffrey ������������������������������������������P1799 Van Heesbeen, Roy ������������������������������������������P200 van Hinsbergh, Victor W. ����������������������������������P668 Van Hoven, Miri ������������������������������������������������P479 VanItallie, Christina M. ������������������������������������P1458 van Leeuwen, Ingeborg ����������������������������������P1893 van Loon, Aaron P. ������������������������������� P101,P1714 Van Ness, Grant �����������������������������������������������P757 van Nieuw Amerongen, Geerten P. ������������������P668 Van Nieuwenhze, Michael ��������������������������������P798 vanOudenaarden, Alexander �������������������������� P1198 VanProoyen, Nancy ���������������������������� P2078,P2419 VanPutten, Sander �������������������������������������������P652 VanSciver, Robert �������������������������������������������P1866 van Steensel, Bas ������������������������������������������P2001 VanValen, David �������������������������������������������������P67 van Westrienen, Jesse �����������������������������������P1623 Van Zandt, Peter A. ������������������������������������������P845 van Zanten, Thomas S. ������������������������������������P939 Van Zundert, Brigitte ���������������������������������������P1366 Varadarajan, Ramya �����������������������������������������P748 Vardi, Noga �����������������������������������������������������P1387 Varela, Lorena ������������������������������������������������P1366 Vargas, Adriana H. ������������������������������������������P1230 Vargas, Christopher ������������������������������������������P479 Vargas, Elizabeth ��������������������������������������������P1903 Vargas, Karina J. ����������������������������������������������P400 Vargas, Pablo ���������������������������������������������������P376 Varjosalo, Markku �������������������������������������������P2268 Varma, Dileep ������������������������������������� P1898,P1900 Vasilev, Alexandr A. ����������������������������������������P2381 Vaskovicova, Michaela ������������������������ P1998, P357 Vásquez Limeta, Alejandra �����������������������������P2041 Vassaux, Maxime �������������������������������������������P2216 Vasudevan, Krishna Kumar. ������������������ P995, P993 Vasudevan, Srividya ���������������������������������������P1024 Vaughan, Joshua ��������������������������������������������P1664 Vaughan, Kevin T. ���������������������������������������������P222 Vavilina, Anastasia D. ���������������������������������������P800 Vavylonis, Dimitrios ���������P447,P923,P1726, P1846 Vazquez, Neftali ������������������������������������������������P290 Vázquez-Nin, Gerardo H. ���������������������������������P674 Veatch, Sarah L. ����������������������������������� P545,P2064 Vecchiarelli, Anthony G. ���������������������� P797, P1539 Vedula, Pavan ������������������������������������������������P1732 Veeranan-Karmegam, Rajalakshmi ����������������P1759 Veetil, Sindhu K. ���������������������������������������������P1831 Vega, Anthony R. ������������������������������������ P593,P931 Vega, Leticia R. ���������������������������������� P1054,P1630 Vega, Matias ��������������������������������������������������� P1181 Veisaga, Maria-Luisa �������P552,P786,P1053, P1627 Vejselova, Djanan ����������������������������������� P282,P287 Veland, Iben R. �����������������������������������������������P1720 VélezAguilera, Griselda ����������������������������������P2041 Velez-Velez, Lisa ��������������������������������������������P1293 Velho, Albertina M. �������������������������������������������P694

 146

Velle, Katrina B. ����������������������������������������������P1734 Velve Casquillas, Guilhem ������������������������������P1073 Vendramini-Costa, Debora B. �������������������������P2308 Venkatesan, Shriram ����������������������������������������P705 Venkateswaran, Niranjan ���������������������������������P292 Ventura, Andrea ����������������������������������������������P1968 Veon, William ��������������������������������������������������P1428 Verde, Fulvia ������������������������������������������ P360,P447 Vergnes, Laurent ��������������������������������������������P2392 Verhey, Kristen J. �������������������������������������P111,P127 Verheyen, Esther M. �����������������������������������������P557 Verlhac, Marie-Hélène ��������������������������������������P228 Verma, Mohit ��������������������������������������������������P1690 Verma, Navin K. �����������������������������������������������P886 Verma, Vikash ������������������������������������������������P1907 Vershinin, Michael ��������������������������������� P128, P715 Vertelov, Grigory K. �����������������������������������������P2227 Vertino, Paula M. �������������������������������������������� P1143 Vesela, Jana ���������������������������������������������������P1438 Veselá, Petra ����������������������������������������������������P357 Vetter, Melanie ������������������������������������������������P1827 Vevea, Jason D. ���������������������������������������������P2332 Veziris, Nicolas �����������������������������������������������P1678 Viais, Ricardo ���������������������������������������������������P975 Viana, Matheus ������������������������������������� P356,P1335 Viarisde Lesegno, Christine ������������������������������P619 Viasnoff, Virgile ����������������������������������������� P36,P918 Vichas, Athea ��������������������������������������������������P2369 Vicogne, Dorothee ������������������������������������������P1480 Vidal, Rene �������������������������������������������������������P580 Vidali, Luis ��������������������������������������������������������P728 Vidi, Pierre ������������������������������������������������������P1236 Vie, Katell �������������������������������������������������������P1354 Vieira, Cristiano P. ������������������������������ P1500,P1505 Vieu, Christophe �����������������������������������������������P875 Vig, Dhruv �������������������������������������������������������P1496 Vig, Monika �����������������������������������������������������P1358 Vignjevic, Danijela M. ������������������������������������� P1154 Vigoreaux, Jim O. �������������������������������������������P2471 Vihinen, Helena ����������������������������������������������P2268 Vijayaraghavan, Balaje �������������������������������������P381 Vijayraghavan, Deepthi S. ��������������������������������P767 Vilhelm, Martin J. ����������������������������������������������P146 Villa, Elizabeth ������������������������������������������ P35,P808 Villanueva, Carolina ������������������������������������������P529 Villarreal, Alex ���������������������������������������������������P173 Vincent, Pierre ������������������������������������������������P2190 Vineyard, Laura ������������������������������������������������P982 Virolle, Thierry ������������������������������������������������P1985 Viscardi, Valeria ����������������������������������������������P1076 Vistein, Rachel ������������������������������������������������P2135 Viswanath, Shruthi ��������������������������������������������P972 Viswanatha, Raghuvir ����������������������������� P466,P885 Visweshwaran, Sai P. �������������������������������������P1979 Vitha, Stanislav �����������������������������������������������P2153 Vitriol, Eric A. ����������������������������������������������������P903 Vivanco, Igor �����������������������������������������������������P288 Vivas-Mejia, Pablo E. �������������������������������������P1969 Vivian, Jay L. ��������������������������������������������������P1832 Vizcarra, Christina L. ���������������������� P82, P86,P1728 Vjestica, Aleksandar ���������������������������������������P2100 Vlassaks, Evi ����������������������������������������������������P460 Vo, BaoHan T. �������������������������������������������������P1963 Voeltz, Gia ��������������������������������������������������������P426 Vogel, Jackie M. ��������������������������������� P1023,P1036 Vogel, Kenneth �������������������������������������������������P600 Vogel, Stephen M. ������������������������������������������P1474 Vogl, A.W.Wayne �������������������������������� P2274,P2385 Voiculescu, Sonia ���������������������������������������������P341 Voituriez, Raphael ��������������������������������������������P376 Vojnar, Tamira �������������������������������������� P972, P1879 Volek, Michael ����������������������������������������������������P23 Volk, Matt ������������������������������������������������������������P10 Volk, Talila ���������������������������������������������������������P370 Volodin, Alexandra ������������������������������������������P2478 von Diezmann, Alex ������������������������������������������P595 Von Dollen, John �������������������������������������������� P2411 von Feilitzen, Kalle ���������������������������������������������P58 von Zastrow, Mark ������������������������������ P1417,P1686 Vorobjev, Ivan A. ������������������������� P133, P134,P1087 Voss, Laura ������������������������������������������������������P648 Voss, Will N. �����������������������������������������������������P648 Voth, Gregory A. ������������������������������������� P100,P907

Votra, SarahBeth ������������������������������������������������P99 Vovk, Andrei ���������������������������������������������������P2037 Vu, Hang T. ���������������������������������������� P1383, P2389 Vukovic, Lidija D. ��������������������������������������������P2036 Vukušić, Kruno �������������������������������������������������P186 Vuong, Linh T. �������������������������������������������������P1757

W

Wachi-Toyooka, Tomoka ����������������������������������P491 Wadsworth, Patricia ����������������� P1768,P1881,P1891 Wagner, Brad ����������������������������������������������������P757 Wagner, Denisa D. �����������������������������������������P1746 Wagner, Elizabeth �������������������������������������������� P611 Wagner, Tobias �����������������������������������������������P2271 Wahedi, Mastura ����������������������������������������������P574 Wahyuni, Ratna ����������������������������������������������P2079 Wait, Eric ������������������������������������������������������������P48 Wakamori, Masatoshi �������������������������������������P2008 Wakeham, Nancy �������������������������������������������P2439 Wakenight, Paul ���������������������������������������������P2481 Wakui, Hideki ��������������������������������������������������P2181 Walcott, Brian ���������������������������������������������������P879 Walczak, Claire E. P238, P245,P1764,P1883,P2262 Walden, Rebecca L. ��������������������������������������� P1100 Wales, Christina T. ��������������������������������������������P289 Walia, Vijay �����������������������������������������������������P1827 Walker, Amy ����������������������������������������������������P2334 Walker, Chandler A. ����������������������������������������P1323 Walsh, Christopher A. �������������������������������������P1572 Walsh, Joseph ������������������������������������������������P1728 Walsh, Rylie B. �������������������������������������������������P397 Walsh, Susan ������������������������������������������� P10,P837 Walter, Andreas ����������������������������������������������P1667 Walter, Peter �������� P675,P712,P1206,P1334,P1509, ������������������������������������������������� P1510,P1511,P2154 Walters, Alison D. �������������������������������������������P2146 Walther, Nike ����������������������������������������������������P232 Walther, Rhian F. ����������������������������������������������P460 Walther, Tobias ������������������������������������P1511,P2149 Walz, Gerd ������������������������������������������������������P1432 Wambaugh, John F. ����������������������������������������P1653 Wan, Adrienne ������������������������������������������������ P1186 Wan, Changxin ��������������������������������������P358,P1199 Wan, Jun ��������������������������������������������������������P1057 Wan, Qiaoqiao ��������������������������������������������������P615 Wan, Zhengpeng ��������������������������������������������P2221 Wang, Aibing ����������������������������������������������������P952 Wang, Baolin ��������������������������������������������������P1826 Wang, Changlin ����������������������������������������������P1584 Wang, Chao-Wen ���������������������������������������������P548 Wang, Chien-Kai ��������������������������������������������P1450 Wang, Chih-Yang �������������������������������������������P1964 Wang, Chuangqi �����������������������������������������������P107 Wang, Chunxin ��������������P531, P2159,P2315,P2331 Wang, Cuei-Ling ����������������������������������� P716,P1000 Wang, Dongdong �������������������������������������������� P1150 Wang, Doudou ������������������������������������������������P1750 Wang, Fengsong ��������������������������������������������P1984 Wang, Haowei ������������������������������������������������P1752 Wang, Hong ������������������������������������������������������P151 Wang, Hongwei ����������������������� P1099,P1101,P2160 Wang, Hua-Yu ������������������������������������������������P1955 Wang, Hui �������������������������������������������������������P1799 Wang, Huichen �������������������������������������������������P284 Wang, Jie ����������������������������������������������������������P700 Wang, Jie-Yu ����������������������������������������������������P258 Wang, Jinhai ���������������������������������������������������P1916 Wang, Juan ����������������������������������������������������P2258 Wang, Junling ������������������������������������� P1387,P2352 Wang, Lei ���������������������������������������������������������P193 Wang, Li ����������������������������������������������������������� P112 Wang, Li ���������������������������������������������������������P2390 Wang, Lin-Ing ����������������������������������������� P252,P256 Wang, Liping �����������������������������������������������������P813 Wang, Meiyan �������������������������������������������������P2337 Wang, Ning �����������������������������������������������������P1846 Wang, Q.Tian ��������������������������������������������������P1582 Wang, Raymond ���������������������������������������������P1336 Wang, Renjie ��������������������������������������������������P2146 Wang, Rong �������������������������������������������P115,P2422 Wang, Ruohan ������������������������������������������������P1305 Wang, Ryan ����������������������������������������������������P1285 Wang, Shaohe ������������������������������������ P1076,P1546

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Wang, Sheng ����������������������������������������������������P670 Wang, Shiyu �����������������������������������������������������P410 Wang, ShiYu ���������������������������������������������������P1242 Wang, Shuoshuo ����������������������������������������������P370 Wang, Shuyuan ����������������������������������������������P1853 Wang, Shyi-Chyi �����������������������������������������������P449 Wang, Sisi ��������������������������������������������������������P277 Wang, Siyuan �������������������������������������������������P1991 Wang, Steven �������������������������������������������������P1993 Wang, Tao ������������������������������������������������������P2155 Wang, Tong-Hong �������������������������������������������P1926 Wang, Tsung-Shing A. ��������������������������������������P716 Wang, Tzu-Chien V. ����������������������������������������P1926 Wang, Wei ��������������������������������������������������������P983 Wang, Wei ������������������������������������������������������P2061 Wang, Weini ���������������������������������������������������P2262 Wang, Wenwen ���������������������� P1752,P1792, P1908 Wang, Won-Jing �����������������������������������������������P209 Wang, Xiangming �������������������������������������������P2362 Wang, Xiaobo �������������������������������������������������P1433 Wang, Xin ���������������������������������������������������������P469 Wang, Xin C. ����������������������������������������������������P806 Wang, XingHao ����������������������������������������������P1292 Wang, Xinnan �������������������������������������������������P2158 Wang, Xueying �����������������������������������������������P1752 Wang, Xuya ���������������������������������������������������� P1184 Wang, Yang ����������������������������������������������������P2416 Wang, Yan Mei �����������������������������������������������P1670 Wang, Yanzhuang ������������������������������������������P1292 Wang, Yarong ���������������������������������������������������P341 Wang, Ya-Ting ��������������������������������������������������P325 Wang, Yidong �������������������������������������������������P1802 Wang, Yilin ������������������������������������������������������P1471 Wang, Ying �������������������������������������������������������P274 Wang, Ying-Xiao �������������������������������������������������P40 Wang, Yiran ������������������������������������������������������P882 Wang, Yong-Dong ������������������������������������������P1963 Wang, Youli �������������������������������������������������������P467 Wang, Yubo ����������������������������������������������������P1223 Wang, Yung-Song ��������������������������������������������P689 Wang, Zhigao ���������������������������������������������������P679 Wangsa, Darawalee �����������������������������������������P353 Warbington, Hailley ����������������������������������������P1612 Ward, E. S. ���������������������������������������������������������P39 Ward, Jordan D. ��������������������������������������������� P1182 Ward, Kenneth W. ��������������������������������������������P573 Ward, Rosa A. ������������������������������������������������P2194 Warecki, Brandt ������������������������������������������������P224 Warnon, Céline �����������������������������������������������P1354 Warren, Ben �����������������������������������������������������P964 Warren, Kiera E. ���������������������������������������������P1721 Warshamana-Greene, Gnana S. ��������������������P2200 Wasiak, Emilia ��������������������������������������������������P230 Wasilk, Amy ����������������������������������������������������P2126 Wasserman, Richard L. ����������������������������������P1379 Watanabe, Gen ������������������������������������������������P753 Watanabe, Hiroshi ������������������������������������������P2030 Watanabe, Kazuhide ����������������������������������������P783 Watanabe, Kazunao �����������������������������������������P491 Watanabe, Natsuki �����������������������������������������P2079 Watanabe, Rikiya ���������������������������������������������P928 Watanabe, Shu-Ichi ���������������������������������������� P1107 Watanabe, Sumiko �����������������������������������������P1559 Waterman, Clare M. �� P103,P646,P666,P917,P952, ������������������������� P1746,P2117,P2145,P2249, P2242 Watson, Lisa �����������������������������������������������������P890 Wattellier, Benoit �������������������������������������������������P45 Watters, Cody P. �����������������������������������������������P839 Watts, Donald ���������������������������������������������������P870 Waxham, Neal M. ���������������������������������������������P544 Way, Michael ��������������������������������������������������P1599 Wayama, Marina ������������������������������������������������P50 Wayt, Jessica L. ��������������������������������� P1260,P1261 Wear, Martin ���������������������������������������������������P1066 Weaver, Abigail A. ���������������������������������������������P731 Weaver, Alissa M. �������������������������������������������P2256 Weaver, Beth A. ������������������������������������ P193,P1057 Weaver, Lesley N. ������������������������������������������P1883 Weaver, Valerie M. �������P1157,P1158,P1160,P1161, ������������������������������������������������������������ P1997,P2373 Webb, Alexis ���������������������������������������������������P2464 Webb, Donna J. �����������������������������������P1155,P1246 Weber, Gregory F. ������������������������������������������P1727 Weber, Janet L. ����������������������������������������������P1586

Weber, Mary ���������������������������������������������������P2410 Webster, Brant ������������������������������������������������ P1211 Webster, Joshua �������������������������������������������������P63 Wedegaertner, Philip B. ����������������������������������P1384 Weeks, Daniel L. ��������������������������������������������P1557 Wei, Bin ���������������������������������������������� P1849,P1867 Wei, Jen-Hsuan ����������������������������������������������P1999 Wei, Li-Na ������������������������������������������������������� P1188 Wei, Ming-Tzo ��������������������������������������������������P714 Weidmann, Max ���������������������������������������������� P1136 Weigel, Aubrey V. �������������������������������������������P2139 Weigert, Roberto ��������������������������������������������P1452 Weihl, Conrad C. ��������������������������������������������P1533 Weimbs, Thomas ����������������������������������������������P407 Weinberg, Josh �����������������������������������������������P1613 Weiner, Alexis T. �����������������������������������������������P976 Weiner, Orion D. ����������������P617,P732,P741,P1431, ������������������������������������������������������������ P2252,P2354 Weir, David B. ���������������������������������������������������P661 Weirich, Kim �����������������������������������������������������P919 Weisman, Lois S. ��������������������������������������������P1371 Weiss, Lucien E. ���������������������������������������������P2148 Weißl, Andreas �����������������������������������������������P1068 Weissman, Jonathan S. ������������������������������������P506 Weissmann, Carina ����������������������������������������P1320 Weitzer, Georg ������������������������������������������������P2371 Welburn, Julie P. ���������������������������������������������P1029 Welch, Matthew D. ����������������������������� P1731,P2214 Wellman, Laurie L. ��������������������������������������������P820 Wells, James A. �������������������������������������� P69,P1421 Wells, Rebecca G. ��������������������������������������������P382 Welsh, Michael J. ���������������������������������������������P147 Welte, Michael A. ��������������������������������������������P1349 Wen, Weijia ����������������������������������������������������P2288 Wen, Ying �������������������������������������������������������P1525 Wen, Zhihui ������������������������������������������������������P707 Wendland, Beverly ��������������������������������� P386,P393 Weng, Fei ���������������������������������������������������������P621 Wenk, Markus R. ����������������������������������������������P535 Werb, Zena �����������������������������������������������������P1964 Wercberger, Racheli ���������������������������������������P1667 Werner, Michael ������������������������������������ P743,P1850 Wernike, Denise �����������������������������������������������P769 Wesolowska, Natalia ��������������������������������������P2024 West, Mary �����������������������������������������������������P2288 West, Matthew ������������������������������������������������P2082 Westerback, Ashley ������������������������������������������P321 Westhorpe, Frederick G. ��������������������������������P1061 Westlake, Christopher J. ��������������������������������P1827 Wetzel, Franziska �������������������������������������������P2271 Wetzel, Laura A. ����������������������������������� P764,P1081 Whalen, Margaret �������������������������������������������P2437 Wheatley, Sally P. �������������������������������������������P2320 Wheeler, Heather ������������������������������������� P55,P535 Wheeler, Matthew ���������������������������������������������P257 Whigham, Arlene ��������������������������������������������P1676 Whitaker, Jessica �����������������������������������������������P70 White, Jason ���������������������������������������������������P2434 White, Katharine A. �����������������������������������������P2281 White, Kenneth L. ���������������������������������������������P345 White, Lauren ������������������������������������������������� P1155 White, Megan �������������������������������������������������P2096 Whitehouse, Logan ������������������������������������������P159 Whitescarver, RyanA ��������������������������������������P2292 Whitlock, Jarred M. �����������������������������������������P2474 Whittemore, Scott R. ��������������������������������������P2318 Whitworth, Gregg �������������������������������������������P1201 Wick, Susan M. �������������������������������������� P832,P842 Wickstead, Bill ������������������������������������������������P1064 Widelitz, Randall �����������������������������������������������P760 Widlund, Per O. ������������������������������������������������P967 Wiedeman, Justin �������������������������������������������P1609 Wiesner, Christiane ���������������������������������������� P1711 Wiggins, Ben L. ����������������������������������������������������P9 Wigins, Paul A. �������������������������������������������������P801 Wignall, Sadie M. ���������P1032,P1870,P1882,P1906 Wiita, Arun ������������������������������������������ P2077,P2319 Wiking, Mikaela ������� P507,P508,P623,P859,P1227, ������������������������������������������������������������ P1782,P2165 Wiktor, Jakub ��������������������������������������������������P2003 Wild, Andre �������������������������������������������������������P884 Wilde, Andrew R. ������������������������������������������������P88 Wildonger, Jill ����������������������������� P111,P1760, P621 Wilkinson, Kevin A. �����������������������������������������P1310

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Wilkinson, Mason ���������������������������������������������P705 Wilkinson, Scott ��������������������������������������P311, P312 Willer, Margaret K. ������������������������������������������P2019 Willet, Alaina H. ������������������������������������ P908,P1848 Willetts, Lian �����������������������������������������������������P316 Williams, Annabelle ������������������������������������������P954 Williams, Blake �������������������������������������� P78, P1482 Williams, Brian ��������������������������������������������������P888 Williams, Claire �������������������������������������������������P621 Williams, Erica I. �����������������������������������������������P645 Williams, Erin R. �����������������������������������������������P455 Williams, James ������������������������������������������������P601 Williams, Michelle A. ���������������������������������������P1291 Williams, Noelle ����������������������������������������������P1955 Williams, Sparkle D. ���������������������������������������P2348 Williamson, Adam P. �������������������������� P2168, P2204 Williamson, Chad D. �����������������������������������������P965 Williamson, Chad �������������������������������������������P1261 Williamson, David R. �������������������������� P1640,P2418 Willis, Adam M. ����������������������������������������������� P1187 Willms, Reegan ������������������������������������������������P748 Wills, Andrea E. ����������������������������������������������P2028 Wilson, Allison K. ��������������������������������������������������P5 Wilson, Beverley ���������������������������������������������P1271 Wilson, Bridget S. �������������������������������������������P1418 Wilson, Christopher ����������������������������������������P1999 Wilson, Clive �����������������������������������������������������P339 Wilson, Hillary �������������������������������������������������������P1 Wilson, Meredith H. ������������������������������� P56, P1352 Wilson, Natalie �����������������������������������������������P1776 Wilson, Nedra �������������������������������������������������P1006 Wilson, Robin E. ���������������������������������������������P1695 Wilson, Sean A. ������������������������������������������������P807 Wilson, Zachary N ����������������������������� P1554, P2082 Winckler, Bettina ��������������P401, P488,P1247,P1301 Winder, Steven J. �������������������������������������������P2041 Winding, Michael ��������������������������������������������P1760 Winge, Dennis ��������������������������������������������������P533 Winkelman, Jonathan D. �������������������������� P84,P891 Winkle, Cortney C. �����������������������������������������P2054 Winsnes, Casper F. ��������������������� P507,P623,P1540 Winter, Dominic ����������������������������������������������P2158 Winterhoff, Moritz �����������������������������������������������P85 Winters, Aidan ������������������������������������ P1200,P1201 Wioland, Hugo ������������������������������������������������P1862 Wirschell, Maureen ���������������������������� P1002, P1003 Wirshing, Alison C. �����������������������������������������P1744 Wirtz, Denis ����������������������������������������������������P2020 Wisdom, Katrina M. ����������������������������������������P1487 Wiseman, Paul W. ������������������������������������������P1359 Wiser, Mark F. �������������������������������������������������P1610 Wissler, Josef H. �����������������������������������������������P346 Wittmann, Torsten �������������������������������������������P1799 Witus, Sam �����������������������������������������������������P1529 Wivagg, Carl �����������������������������������������������������P795 Wlikinson, Anthony J. �������������������������������������P1399 Włoga, Dorota ��������������������������������������������������P993 Wofford, Amina �������������������������������������������������P810 Wojcik, Michal ��������������������������������������� P389,P1875 Wolf, Kayla J. ��������������������������������������������������P1484 Wolfe, Lynne ���������������������������������������������������P1281 Wolfenden, Laurelin ����������������������������������������P1947 Wolff, Ian D. ����������������������������������������������������P1032 Wolff, Ian D. ����������������������������������������������������P1882 Wolske, Amanda ���������������������������������������������P2251 Wolyniak, Michael J. ������������������������������� P832,P842 Won, Jennifer ������������������������������������������������� P1151 Won, MinHo ����������������������������������������������������P1093 Won, Minho ����������������������������������������������������P2205 Won, Younsun ������������������������������������������������P2398 Wong, Aaron K. ����������������������������������������������P1545 Wong, Adrian Y. ���������������������������������� P1515,P1517 Wong, Andrew ������������������������������������P1137, P1496 Wong, Felix 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AUTHOR INDEX Wong-Ho, Elaine ����������������������������������������������P890 Wood, David K. �����������������������������������������������P2259 Wood, Kevin �����������������������������������������������������P735 Wood, Laura A. �����������������������������������������������P2089 Woodard, Thaddeus K. �������������������������������������P386 Woodley, Sarah K. ��������������������������������������������P850 Woodman, Sara E. �����������������������������������������P1241 Woodruff, Jeffrey B. ������������������������������������������P967 Woods, Christopher ����������������������������������������P1608 Woods, Dori C. �������������������������������������������������P669 Worcester, Colette ��������������������������������������������P384 Wordinger, Robert J. ���������������������������������������P2447 Workman, Jerry L. ������������������������������������������P2389 Worman, Howard J. ������������������������������������������P462 Wrabetz, Lawrence �����������������������������������������P2172 Wren, Jonathan D. ������������������������������ P1019,P2005 Wright, Forrest ����������������������������������������������������P99 Wright, Graham D. ������������������������������������������P1214 Wright, Gus �����������������������������������������������������P1441 Wright, Shaela ������������������������������������������������P1963 Wright, Todd A. �������������������������������������������������P806 Wu, Bin �������������������������������������������������������������P438 Wu, Bing ���������������������������������������������������������P2194 Wu, Chao-Ting �����������������������������������������������P1991 Wu, Chengbiao �����������������������������������������������P1324 Wu, Chia-Ching ������������������������������������������������P616 Wu, Chieh-Hsi ���������������������������������������� P258,P347 Wu, Chien-Ting �������������������������������������������������P209 Wu, Chuanjin ����������������������������������������������������P639 Wu, Di �������������������������������������������������������������P1076 Wu, Gang �������������������������������������������������������P1963 Wu, Guangyu ����������������������������������������������������P441 Wu, Hai-Yin ���������������������������������������� P1022,P1878 Wu, Hsu F. ��������������������������������������������������������P899 Wu, Hua-Lin ����������������������������������������������������P1483 Wu, Huihui ������������������������������������������������������P1792 Wu, Jianli ����������������������������������������������������������P181 Wu, Jian-Qiu �����������������������P188,P189,P191,P1846 Wu, Jun ����������������������������������������������������������P1476 Wu, Kay L. ������������������������������������������������������P2399 Wu, Kenneth K. ���������������������������������������������� P1178 Wu, Lani F. ��������������������������������������������������������P617 Wu, Leeju ���������������������������������������������������������P625 Wu, Ping �����������������������������������������������������������P760 Wu, Qingyu �����������������������������������������������������P1578 Wu, Qiong ���������������������������������������������������������P153 Wu, Rentian ���������������������������������������������������� P2011 Wu, Ruey-Mei �������������������������������������������������P2158 Wu, Shu-Zon ��������������������������������������������������P1705 Wu, Tiffany T. ��������������������������������������������������P1530 Wu, Tsung S. ��������������������������������������������������P1791 Wu, Wei ������������������������������������������������������������P462 Wu, Wei ����������������������������������������������������������P2049 Wu, Xiaoyang �������������������������������������������������P2391 Wu, Xjuju ��������������������������������������������������������P2392 Wu, Xufeng ���������������������������������������������������������P87 Wu, Yao ����������������������������������������������������������P1471 Wu, Yicong ���������������������������������������������������������P44 Wu, You ���������������������������������������������������������� P1199 Wu, Youjun ����������������������������������������������������� P2111 Wu, Yueh-Fu ������������������������������������������� P252,P253 Wu, Yueh-Fu O. ����������������������������������������������P1704 Wu, Yumei ������������������������������������������������������P1282 Wu, Zhanghan ������������������������������������������������P2242 Wu, ZhiYong ���������������������������������������������������P1916 Wung, William ���������������������������������������������������P479 Wurm, Christian A. ������������������������������������������P2232 Wustrow, David �����������������������������������������������P1916 Wyatt, Tom P. ����������������������������������������������������P604

X

Xenarios, Ioannis ��������������������������������������������P1541 Xi, Joan ����������������������������������������������������������P2137 Xi, Linghe ���������������������������������������������������������P863 Xia, Hui ������������������������������������������������P1187,P1688 Xia, Yuntao ������������������������������������������P1141,P1228 Xia, Yuqing �������������������������������������������������������P969 Xiang, Jialing �������������������������������������������� P74,P670 Xiang, Siheng ���������������������������������������������������P625 Xiang, Yang ������������������������������������������������������P621 Xiao, Qiang �������������������������������������������������������P858 Xiao, Yuan ������������������������������������������������������P1939 Xie, Shicong ���������������������������������������������������P2359

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Xie, Ying ���������������������������������������������������������P1305 Xie, Zhigang ���������������������������������������������������P2374 Xiong, Xin �������������������������������������������������������P1305 Xu, Albert ��������������������������������������������������������P2319 Xu, Cangshan �������������������������������������������������P2139 Xu, Daiying �����������������������������������������������������P1296 Xu, Jie ������������������������������������������������������������P1259 Xu, Jing ������������������������������P121,P122,P123,P1753 Xu, Ke ���������P389,P429,P932,P1008,P1484,P1659, ������������������������������������������������������������ P1875,P1894 Xu, Leilei ���������������������������������������������������������P1908 Xu, Song ���������������������������������������������������������P2401 Xu, Tao �����������������������������������������������������������P2131 Xu, Wenlong �����������������������������������������������������P723 Xu, Yanan �������������������������������������������������������P1009 Xu, Zack Z. �����������������������������������������������������P2460 Xue, Ye �����������������������������������������������������������P1701 Xue, Zenghui ��������������������������������������������������P1852

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Yang, Xiaohua ������������������������������������������������P1626 Yang, Xiaoyang ������������������������������������������������P751 Yang, Xinyi ������������������������������������������������������P1550 Yang, Yanmin ���������������������������������������������������P983 Yang, Yanqin ��������������������������������������������������P1578 Yang, Yixin ���������� P304,P1183,P1935,P1939,P1942 Yang, Yuchen ���������������������������������������������������P149 Yano, Tomoki ������������������������������������������ P641,P643 Yao, Bing ��������������������������������������������������������P1916 Yao, Jun ������������������������������������������������������������P354 Yao, Long-fang �����������������������������������������������P1353 yao, Phil ����������������������������������������������������������P1752 Yao, Tso-Pang ��������������������������������������������������P181 Yao, William W. �����������������������������������������������P1984 Yao, Xuebiao 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��������������������������������������������P716 Yeh, Ellen �������������������������������������������������������P1595 Yeh, Hsi-Wen ��������������������������������������������������P1982 Yeh, Ting-Yu ���������������������������������������������������P1770 Yeh, Victor ����������������������������������������������������������P65 Yeh, Yi-Ting ������������������������������������������������������P729 Yemets, Alla I. ��������������������������������������P1177,P2322 Yen, Eric ���������������������������������������������������������P1036 Yeo, Jongchan ��������������������������������������������������P806 Yeo, Lydia ���������������������������������������������������������P933 Yeon, Tae Y. ������������������������������������������������������P973 Yeong, Foong M. ������������������������� P251,P840,P2415 Yeung, Howard T. ���������������������������������������������P974 Yewdell, William T. ������������������������������������������P2015 Yi, Jason 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The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

AUTHOR INDEX Yoshino, Ken-ichi �������������������������������� P2180,P2473 Yoshino, Kenji �������������������������������������������������������P2 You, Dong-Ju ����������������������������������������������������P956 You, Eunae ����������������������������������������������������� P1159 You, Hyung-Keun �������������������������������������������P1581 You, Sungyong ���������������������������������������������������P39 Youle, Richard J. �����������P531, P2159,P2315,P2331 Young, Lorna E. ������������������������������������������ P83,P89 Young, Scott L. �����������������������������������������������P2462 Yount, Amber L. ����������������������������������������������P1764 Yu, Allen T. ��������������������������������������������������������P343 Yu, Che-Hang ��������������������������� P243, P1022,P1878 Yu, Chia J. ������������������������������������������������������P1427 Yu, Chunmiao ���������������������������������������������������P304 Yu, Hong-Guo ��������������������������������������������������� P211 Yu, Hongtao ����������������������������������������������������P1059 Yu, Huijuan �������������������������������������������������������P254 Yu, Jinyeong ���������������������������������������������������P1443 Yu, Jiun-Yann �����������������������������������������������������P40 Yu, Kristina R. ���������������������������������������������������P847 Yu, Kuai ����������������������������������������������������������P2474 Yu, Linda ���������������������������������������������� P528,P1419 Yu, Peter Y. �����������������������������������������������������P1967 Yu, Rong �����������������������������������������������������������P519 Yu, Ryan ���������������������������������������������������������P2424 Yu, Shannon ���������������������������������������������������P2472 Yu, Shiyan ������������������������������������������������������ P1411 Yu, Shuhua �������������������������������������������������������P965 Yu, Weimiao �����������������������������������������������������P449 Yu, Wenqian ���������������������������������������������������P1320 Yu, Xiaobo ������������������������������������������������������P2425 Yu, Ziding �������������������������������������������������������P1620 Yu, Zulin ���������������������������������������������������������P1075 Yuan, Feng Ning �����������������������������������������������P493 Yuan, Huijuan ���������������������������������������������������P504 Yuan, Lin ����������������������������������������������������������P429 Yuan, Shiaulou �������������������������������������������������P150 Yucel, Deniz ���������������������������������������������������P1553 Yudushkin, Ivan ����������������������������������������������P1406 Yue, Jiping ������������������������������������������������������P2391 Yue, Xihua ��������������������������������������������������������P427 Yue, Yang ��������������������������������������������������������� P111 Yuen, Kelly ���������������������������������������������������������P12 Yun, Hongmin �������������������������������������������������P2456 Yun, Jun-Won ���������������������������������������������������P754 Yunghans, Allison ���������������������������������������������P890 Yurieva, Marina ����������������������������������������������P1214 Yusuf, Mohamed ��������������������������������������������P1080

Z

Zaal, Kristina J. �����������������������������������������������P1798 Zabezhinsky, Dmitry ���������������������������������������P1337 Zacharchenko, Thomas ����������������������������������P1439 Zahra, Fiddia ����������������������������������������������������P401 Zaidel-Bar, Ronen �������������������� P953, P1471,P2175 Zajac, Olivier �������������������������������������������������� P1153 Zajicova, Alena �������������������������������������������������P819 Zaki, Nazar �����������������������������������������������������P1927 Zallen, Jennifer �����������������������������������������������P1574 Zanella, Fabian �����������������������������������������������P2266 Zanin, Esther ����������������������������������������������������P187 Zanini, Martine ������������������������������������������������P2302 Zarco-Olvera, Gabriela �����������������������������������P2482 Zareian, Ramin �����������������������������������������������P2288 Zaroli, Johann ���������������������������������������������������P479 Zaug, Arthur ������������������������������������������������������P863 Zebarjadi, Navid ���������������������������������������������P1372 Zeeshan, HafizMaher A. ���������������������������������P2309 Zeitlin, Benjamin D. ����������������������������������������P2424 Zeituni, Erin M. �����������������������������������������������P1352 Zelaya, Rene A. ����������������������������������������������P1545 Zelter, Alex ��������������������������������������������������������P971 Zelter, Alex �������������������������������������������� P972,P1897 Zerfas, Patricia �������������������������������������������������P530 Zerial, Marino �������������������������������������������������P2068 Zhan, Cheng �����������������������������������������������������P766 Zhang, An-Sheng ���������������������������������������������P574 Zhang, Bin ��������������������������������������������������������P890 Zhang, Bing ������������������������������������������������������P302 Zhang, Chuanmao ������������������������������������������P1213 Zhang, Donghui ������������������������������������������������P969 Zhang, Fangliang ���������������������������������������������P989 Zhang, Feng ���������������������������������������������������P1993

Zhang, Haolin ���������������������������������������������������P753 Zhang, Hongyong ���������������������������������������������P277 Zhang, Huaiying ���������������������������������������������P1058 Zhang, Huaiyuan �������������������������������������� P74,P670 Zhang, Hui �������������������������������������������� P667,P2400 Zhang, Jason Y. ������������������������������������������������P238 Zhang, JiangWen �������������������������������������������P2276 Zhang, Jianhua �������������������������������������������������P301 Zhang, Jin ���������������������������������������������������������P591 Zhang, Jing �����������������������������������������������������P2266 Zhang, Juanlian ����������������������������������������������P1654 Zhang, Junmei ������������������������������������������������P1506 Zhang, Kai ����������������������������������������������������������P54 Zhang, Ke �������������������������������������������������������P2035 Zhang, Kelvin �������������������������������������������������P1570 Zhang, Lan �����������������������������������������������������P1380 Zhang, Li ��������������������������������������������������������P1850 Zhang, Liangyu �����������������������������������������������P1874 Zhang, Mingzi ������������������������������ P821,P823,P2380 Zhang, Nan �����������������������������������������������������P1766 Zhang, Ran �����������������������������������������������������P1545 Zhang, Richard �������������������������������������������������P574 Zhang, Shaobing O. �����������������������������������������P547 Zhang, Shaojie �����������������������������������������������P1989 Zhang, Siyuan ��������������������������������������������������P824 Zhang, Songlin �����������������������������������������������P2160 Zhang, Vivian ��������������������������������������������������P2421 Zhang, Wan ������������������������������������������������������P784 Zhang, Wan ����������������������������������������������������P1970 Zhang, Wei �������������������������������������������������������P786 Zhang, Xiao ���������������������������������������������������� P1411 Zhang, Xu �������������������������������������������������������P1748 Zhang, Yan ���������������������������������������� P1820, P2120 Zhang, Yifan �����������������������������������������������������P561 Zhang, Yin ������������������������������������������������������P1984 Zhang, Ying ������������������������������������������ P707,P1081 Zhang, Yingfan �����������������������������������������������P1712 Zhang, Yongbo �������������������������������������������������P517 Zhang, Yorke ����������������������������������������������������P393 Zhang, Ziyao ��������������������������������������������������P2372 Zhao, Boxin ����������������������������������������������������P1690 Zhao, Charles ��������������������������������������������������� P114 Zhao, Chongbei ������������������������������������������������P365 Zhao, Jian ���������������������������������������������������������P519 Zhao, Lu �����������������������������������������������������������P150 Zhao, Michael L. ������������������������������������� P718,P785 Zhao, Ningning �������������������������������������������������P574 Zhao, Peijun ���������������������������������������������������P1644 Zhao, Teng ������������������������������������������������������P1296 Zhao, Xiaoli ������������������������������������������ P820,P2426 Zhao, Yu �������������������������������������������������������������P74 Zhao, Zhiling ��������������������������������������� P1076,P1546 Zhen, Christopher �������������������������������������������P2331 Zheng, Changyu �����������������������������������������������P576 Zheng, Cunni ��������������������������������������������������P1212 Zheng, Jianqun �������������������������������������������������P994 Zheng, Liuliu �����������������������������������������������������P902 Zheng, Liwei ���������������������������������������������������P2120 Zheng, Minghao ���������������������������������������������P2155 Zhong, Jun �������������������������������������������������������P721 Zhou, Bin ��������������������������������������������������������P1802 Zhou, Chuankai ������������������������������������������������P707 Zhou, Fan �������������������������������������������������������P1449 Zhou, Han-Jie �������������������������������������������������P1916 Zhou, Jiajia �����������������������������������������������������P1984 Zhou, Julie X. ���������������������������������������������������P157 Zhou, Li ����������������������������������������������������������P1353 Zhou, Lixin ������������������������������������������������������ P1151 Zhou, Ruyun ����������������������������������������������������� P112 Zhou, Shu �������������������������������������������������������P1984 Zhou, Yi ������������������������������������������������������������P324 Zhou, Yi ����������������������������������������������������������P2456 Zhou, Yong �������������������������������������������������������P541 Zhou, Yuan ������������������������������ P1099,P1101,P2160 Zhou, Zhou �����������������������������������������������������P1858 Zhu, Hao ���������������������������������������������������������P1820 Zhu, Jin �����������������������������������������������������������P2102 Zhu, Jun ���������������������������������������������������������P1578 Zhu, Lei ������������������������������������������������������������P994 Zhu, Mang �������������������������������������������������������� P711 Zhu, Qingfeng �������������������������������������������������P1707 Zhu, Ruijun �������������������������������������������������������P374 Zhu, Wanqiu �����������������������������������������������������P368 Zhu, Xiaodong ���������������������������������������� P502,P978

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Zhu, Xiaoyan ������������������������������������������ P163,P996 Zhu, Xin ����������������������������������������������������������P1816 Zhu, Xueliang ��������������������������������������� P994,P1009 Zhu, Yaxing �������������������������������������������������������P149 Zhu, Yihua ��������������������������������������������������������P191 Zhu, Yongqing ��������������������������������������������������P348 Zhu, Zhiwen ����������������������������������������������������P1857 Zhuang, Xiaowei ��������������������������������� P1991,P1993 Zhuang, Xiaoxuan ��������������������������������������������P195 Zhuravlev, Yelena ���������������������������������� P168, P175 Ziaie, Babak ���������������������������������������������������P1235 Zieske, Katja �����������������������������������������������������P730 Zigmond, Richard E. ���������������������������������������P1314 Zilberman, Yuliya ����������������������������������������������P770 Zilman, Anton �������������������������������������������������P2037 Zimak, Jan ����������������������������������������������������������P96 Zimanyi, Christina M. ��������������������������������������P1399 Zimic, Mirko ����������������������������������������������������P1678 Zimmerberg, Joshua ��������������������������������������P1446 Zimmermann, Dennis ���������������������������������������P100 Zimmermann, Maike ������������������������������� P277,P293 Zinn, Ashtyn E. ����������������������������������� P2174,P2245 Zipp, Brandon �������������������������������������������������P1028 Zipursky, S.Lawrence �������������������������������������P1570 Zlatic, Stephanie ��������������������������������� P1289,P2135 Zmorzynska, Justyna ���������������������������������������P475 Zobiri, Olivia ���������������������������������������������������P2302 Zolezzi, Francesca �����������������������������������������P1214 Zoncu, Roberto ����������������������������������� P1674,P2326 Zong, Hailing ��������������������������������������������������P2262 Zou, Donghua �������������������������������������������������P2393 Zou, Hongye �����������������������������������������������������P279 Zou, Yue ���������������������������������������� P266,P267,P273 Zukowski, Stephanie A. ����������������������������������P1389 Zuniga-Sanchez, Elizabeth ����������������������������P1570 Zunitch, Matthew A. ������������������������������������������P397 Zurl, Andrea ���������������������������������������������������� P1168

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AUTHOR INDEX

author disclosures The ASCB requires that audiences be informed of presenters’ (speakers, authors, and contributors) academic and professional affiliations, and disclosure of any significant financial interest or other relationship with the manufacturer(s) of any commercial product(s) discussed in a presentation. This policy allows the listener/attendee to be fully informed in evaluating the information being presented. Disclosure includes any relationship that may bias one’s presentation or which, if known, could give the perception of bias. These situations may include, but are not limited to: 1) stock options or bond holdings in a for-profit corporation or self-directed pension plan, 2) research grants, 3) employment (full-or part-time), 4) ownership or partnership, 5) consulting fees or other remuneration, 6) non-remunerative positions of influence such as officer, board member, trustee, or public spokesperson, 7) receipt of royalties, and 8) speakers bureau.

Author



Disclosure–Institution

Abousawan, John Research Grant- Ryerson University Adam, Cecile Research Grant- NSERC Adams, Bruce Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Xcell Biosciences Inc. Agresti, Jeremy Employment (full or part-time)- Bio-Rad Akan, Ilhan Employment (full or part-time)- NIH / NIDDK Akhtar, Tasleem Research Grant- Higher Education Commission Pakistan Alam, Md Badrul Research Grant- BK 21 Plus Alexander, Richard Ownership or partnership- Stowers Institute for Medical Research Alm, Tove Ownership or partnership- Antibodypedia Amezcua, Karina Employment (full or part-time)- Celprogen Anderson, Daniel Employment (full or part-time)- Cleave Biosciences Arrial, Alexis Employment (full or part-time)- Hybrigenics Services Barbieri, Manuel Research Grant- Florida International University Bardag-Gorce, Fawzia Employment (full or part-time)- Emmaus life Sciences, Inc. Baron, Sylvain Employment (full or part-time)- Cellecta, Inc. Barron, Francie Employment (full or part-time)- Nanomedical Diagnostics Barroso, Margarida Employment (full or part-time)- Albany Medical College Bee, Yong Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Nil Belaidi, Jean-Philippe Employment (full or part-time)- L’Oreal Bellini, Maria Stock options or bond holdings in a for-profit corporation or self-directed pension plan- IPEN-CNEN/SP Bernal, Miguel Ownership or partnership- L’Oreal Berteloite, Benjamin Employment (full or part-time)- Innopsys SA Bhaskar, Rachel Research Grant- NIH Bisht, Jitender Research Grant- University of Wyoming Block, Jennifer Research Grant- Deutsche Forschungsgesellschaft Bordet, Thierry Employment (full or part-time)- TROPHOS Stock options or bond holdings in a for-profit corporation or self-directed pension plan- TROPHOS Boulanger, Corinne Employment (full or part-time)- NCI/CCR Braga, Marina Stock options or bond holdings in a for-profit corporation or self-directed pension plan- UNIVERSITY OF SÃO PAULO Brakebusch, Cord Employment (full or part-time)- BRIC Copenhagen Brisken, Cathrin Employment (full or part-time)- Swiss Institute for Experimental Research Bruehmann, Stefan Research Grant- Deutsche Forschungsgesellschaft Bruyere, Celine Research Grant- FRIA-FNRS Buxeda, Rosa Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of Puerto Rico Byrne, Ronan Employment (full or part-time)- SiriusXT Caballero, Manuel Research Grant- US Air Force Caberlotto, Elisa Employment (full or part-time)- L’Oreal Campbell, A Receipt of royalties- Trinity, publisher of textbook. Campos, Silvana Gisele Employment (full or part-time)- UNESP Cano-Martínez, Agustina Research Grant- INCICH: 12-756 to CMA Research Grant- CONACyT: 169736 to CMA Cappione, Amedeo Employment (full or part-time)- MilliporeSigma, Merck KGaA Carlier, Marie-France Employment (full or part-time)- CNRS France Cassereau, Luke Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Xcell Biosciences Inc. Castle, Brian Research Grant- National Institute of Health (NIH) Cater, Sean Employment (full or part-time)- Bio-Rad Cejka, Cestmir Research Grant- Grant Agency of the Czech Republic 14-12580S Cejkova, Jitka Research Grant- Grant Agency of the Czech Republic 14-12580S Chaiseha, Yupaporn Research Grant- Suaranaree University of Technology Chaudry, Ghulam Employment (full or part-time)- Eagle Applied Sciences

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Author



Disclosure–Institution

Chen, Anan Chen, Kunning Chen, Pengchin Chen, Xian-Ming Chenchik, Alexander Chew, Jennifer Cho, Eui-Sic Choi, Hwajung Chow, Tianna Chu, Felix Cimino, George

Research Grant- Natural Sciences and Engineering Research Council of Canada Research Grant- Nanyang Technological University Employment (full or part-time)- Bio-Rad Research Grant- NIH Employment (full or part-time)- Cellecta, Inc. Employment (full or part-time)- Bio-Rad Research Grant- National Research Foundation of Korea Research Grant- National Research Foundation of Korea Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Xcell Biosciences Inc. Employment (full or part-time)- Genentech Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Accelerated Medical Diagnostics Clark, Abbot Consultant, Financial support- Sanofi-FOVEA:Code C (Consultant) ;Genzyme:Code C (Consultant) ;Aerie Pharmaceuticals:Code C (Consultant) ;ISIS Pharmaceuticals:Code C (Consultant) ;Reata Pharmaceuticals:Code F (Financial Support) ;NiCox Research Institute:Code F (Financial Support) Research Grant- NIH Clark, Richard Ownership or partnership- Neomatrix Therapeutics, Inc. Stony Brook, NY 11790 Clinton, James Employment (full or part-time)- ATCC Clovis, Yoanne Employment (full or part-time)- NemaMetrix Inc. Cluett, Edward Employment (full or part-time)- Ithaca College Collura, Vincent Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Hybrigenics Services Collura, Vincent Employment (full or part-time)- Hybrigenics Services Condeelis, John Ownership or partnership- MetaStat Consulting fees or other remuneration- Deciphera and MetaStat Conkar, Deniz Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Koc University Corbett, Kevin Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of California, San Diego Crooke, Stanley Employment (full or part-time)- IONIS Pharmaceuticals, Inc. Culfa, Efraim Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Koc University Cullen, Valerie Consulting fees or other remuneration- Aldeyra Therapeutics Cyr, Daniel Research Grant- NSERC da Silva, Evelin Stock options or bond holdings in a for-profit corporation or self-directed pension plan- IPEN-CNEN/SP Dardick, Joseph Research Grant- Harrison Undergraduate Research Award Dayam, Roya Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Ryerson De Hoyos, Cheryl Employment (full or part-time)- IONIS Pharmaceuticals, Inc. De Maziere, Ann Consulting fees or other remuneration- Genentech Denat, Laurence Employment (full or part-time)- L’Oreal Dernburg, Abby Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of California, Berkeley Desai, Neil Employment (full or part-time)- Aadigen LLC Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Celgene Deshmukh, Abhijit Ownership or partnership- Jawaharlal nehru university DeSouza, Rebecca Employment (full or part-time)- Precision NanoSystems Inc. Detmar, Michael Research Grant- LVMH Recherche Diehl, Paul Employment (full or part-time)- Cellecta, Inc. Dimchev, Georgi Research Grant- Deutsche Forschungsgesellschaft Dimitrov, Ariane Employment (full or part-time)- L’Oreal Divita, Gilles Employment (full or part-time)- Aadigen LLC Djakovic, Stevan Employment (full or part-time)- Cleave Biosciences Do, Duc Employment (full or part-time)- Bio-Rad Dolman, Nicholas Employment (full or part-time)- Thermo Fisher Scientific Doudna, Jennifer Ownership or partnership- Editas Medicine Ownership or partnership- Intellia Therapeutics Ownership or partnership- Caribou Biosciences Scientific Advisor- Caribou Biosciences Scientific Advisor- Intellia Therapeutics Scientific Advisor- eFFECTOR Therapeutics Employment (full or part-time)- HHMI Executive Director- Innovative Genomics Initiative Scientific Advisor- Driver Research Grant- HHMI Research Grant- Roche The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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Author



Downey, Bryan Duffy, Heather Dumas, Marc Dwyer, Noelle Eilstein, Joan Erdmann, Dominique Eunbi, Jo Fadil, Sana Fahy, Kenneth Faix, Jan Falleiros-Junior, Luiz Roberto Farmer, Andrew Ferrada, Luciano Firat-Karalar, Elif Foreman, Oded Franchi, Jocelyne Frangou, Costa Frenz, Lucas Fujita, Ayano Gabelev, Liliya Garachtchenko, Tatiana Genisson, Jean Luc George, Andrea Gharakhanian, Editte Ghosh, Richik Goldsmith, Brett Goldsmith, Jennifer Gotting, Kirsten Greiner, Doug Gunning, Peter Gupta, Nidhi Haas, Vanessa Hall, Sallie Hamao, Kozue Hammad, Osama Hanover, John Hartnett, Andrej Haugwitz, Michael Hemmat, Mahya Henderson, Paul Hirotsu, Yoshifumi Holan, Vladimir Hong, Soonjin Horita, Henrick Horwitz, Alan Howard, Jason Huang, Pei-Hsin Huesca-Gómez, Claudia Hughes, Thom Hune, Samantha Hwang, Joseph Iimori, Makoto Ikebe, Mitsuo Ikegami, Amanda Inagaki, Naoyuki Ito, Shuichi

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Disclosure–Institution

Research Grant- Pfizer Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Xcell Biosciences Inc. Consulting fees or other remuneration- University of Utah - Frank Sachse lab Employment (full or part-time)- LVMH Recherche Research Grant- NIH Employment (full or part-time)- L’Oreal Employment (full or part-time)- L’Oreal Employment (full or part-time)- Korea basic science institute Speakers bureau- Univer Employment (full or part-time)- SiriusXT Employment (full or part-time)- Hannover Medical School Employment (full or part-time)- UNESP Employment (full or part-time)- Takara Bio USA, Inc. Research Grant- Concepcion University Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Koc University Employment (full or part-time)- Genentech Employment (full or part-time)- LVMH RESEARCH Employment (full or part-time)- Cellecta, Inc. Employment (full or part-time)- Bio-Rad Research Grant- JSPS Stock options or bond holdings in a for-profit corporation or self-directed pension plan- UC Berkeley Employment (full or part-time)- Takara Bio USA, Inc. Ownership or partnership- L’Oreal Employment (full or part-time)- NCI/CCR Research Grant- California State University Long Beach Employment (full or part-time)- Thermo Fisher Scientific Ownership or partnership- Nanomedical Diagnostics Employment (full or part-time)- Genentech Ownership or partnership- Stowers Institute for Medical Research Employment (full or part-time)- Bio-Rad Consulting fees or other remuneration- Novogen Pty Ltd Research Grant- the Board of Novogen Employment (full or part-time)- Genentech Research Grant- Deutsche Forschungsgesellschaft Research Grant- US Air Force Research Grant- JSPS KAKENHI Employment (full or part-time)- SiriusXT Employment (full or part-time)- NIH / NIDDK Employment (full or part-time)- Illumina Employment (full or part-time)- Takara Bio USA, Inc. Research Grant- National Institute of Health (NIH) Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Accelerated Medical Diagnostics Employment (full or part-time)- Saiseikai Toyoura Hospital Research Grant- Grant Agency of the Czech Republic 14-12580S Employment (full or part-time)- Cytoskeleton, Inc. Employment (full or part-time)- Cytoskeleton, Inc. Employment (full or part-time)- Allen Institute for Cell Science Employment (full or part-time)- SiriusXT Research Grant- National Taiwan University Hospital Research Grant- CONACyT: 179967 to HGC Ownership or partnership- Montana Molecular Employment (full or part-time)- Eagle Applied Sciences Employment (full or part-time)- MilliporeSigma Staff members of an endowed course at Kyushu University funded by a donation- Taiho Pharmaceutical Co. Research Grant- NIH, Korea Basic Science Institute Grant Stock options or bond holdings in a for-profit corporation or self-directed pension plan- IPEN-CNEN/SP Stock options or bond holdings in a for-profit corporation or self-directed pension plan- a JSPS Grant-in-Aid for Scientific Research on Innovative Areas Employment (full or part-time)- Olympus Corporation

The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

Author Jang, Ik Soon Jauset, Cristina Javier, Leanne Javorkova, Eliska Jethwa, Devina Johansson, Hans Jones, Christophe Juarez, Edwin Juckem, Laura Juma’at, Muhd Jung, Hyun Suk Kada, Takeshi Kage, Frieda Kang, Byeong-Cheol Kang, In Soon Kang, Kidong Kang, Se-Hui Kaplunov, Jessica Kasprowicz, Richard Kato, Yoshiki Kato, Yoshiki Kaufman, Gili Kawamura, Masaki Kawata, Junko Kawata, Yasunobu Kellogg, Mariko Khrebukova, Irina Kim, Bongjun Kim, Dayoung Kim, Deok-Ho Kim, Dong-Hwee Kim, Min Jung Kim, Rang Ie Kim, So-Young Kim, Uh-Hyun Kim, Yong Jin Kim, Yoon Young Kim, Young Ho Kim, Yumi Kinoshita, Makoto Kiss von Soly, Szerenke Kitao, Hiroyuki Klein, Jonathon Klose, Christian Klumperman, Judith Koca, Yildiz Koiso, Yurika Kokaji, Yoshito Kollasser, Jana Komarov, Andrei Kostow, Nora Koyoshi, Masatoshi Ku, Seung-Yup Kumar, Brajesh Kushiya, Akiho Kushiya, Akiho Kwon, Jeongwoo Lagraulet, Adriana Law, Andy Leaver, Tim Lebofsky, Ronald Lee, Ae Sin



Disclosure–Institution

Employment (full or part-time)- Korea Basic Science Institute Consulting fees or other remuneration- Programa Impuls UdL Employment (full or part-time)- Bio-Rad Research Grant- Grant Agency of the Czech Republic 14-12580S Research Grant- BBSRC Employment (full or part-time)- LGC Biosearch Technologies Employment (full or part-time)- L’Oreal Research Grant- University of Southern California Employment (full or part-time)- Mirus Bio LLC Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Nil Research Grant- Korea Basic Science Institute Grant, Global Frontier Research Grant Employment (full or part-time)- Saiseikai Toyoura Hospital Research Grant- Deutsche Forschungsgesellschaft Research Grant- KHIDI Research Grant- NRF Stock options or bond holdings in a for-profit corporation or self-directed pension plan- BK21 Employment (full or part-time)- Korea Basic Science Institute Employment (full or part-time)- LGC Biosearch Technologies Employment (full or part-time)- Phase Focus Limited Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe Univ Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe Univ Employment (full or part-time)- Volpe Research Center, ADA Foundation Employment (full or part-time)- Saiseikai Toyoura Hospital Ownership or partnership- Kawata Junko Clinic Employment (full or part-time)- Saiseikai Toyoura Hospital Employment (full or part-time)- Illumina Employment (full or part-time)- Illumina Research Grant- Seoul National University Ownership or partnership- Korea Advanced Institute of Sciences and Technology Ownership or partnership- NanoSurface Biomedical Research Grant- National Research Foundation of Korea Research Grant- Korea Food Research Institute Research Grant- NRF Employment (full or part-time)- ASAN Medical Center Research Grant- Korean Research Foundation Research Grant- KHIDI Research Grant- KHIDI Research Grant- National Research Foundation of Korea Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Johns Hopkins University Research Grant- Ministry of Education, Japanese Goverrnment Employment (full or part-time)- Cleave Biosciences Staff members of an endowed course at Kyushu University funded by a donation- Taiho Pharmaceutical Co. Employment (full or part-time)- St. Jude Children’s Research Hospital Employment (full or part-time)- Lipotype, GmbH Consulting fees or other remuneration- Genentech Research Grant- Icahn School of Medicine at Mount Sinai Research Grant- The University of Tokyo Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe Univ Research Grant- Deutsche Forschungsgesellschaft Employment (full or part-time)- Cellecta, Inc. Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of California, Berkeley Employment (full or part-time)- Saiseikai Toyoura Hospital Research Grant- KHIDI Employment (full or part-time)- Cleave Biosciences Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Employment (full or part-time)- Chungbuk National University Employment (full or part-time)- Innopsys SA Employment (full or part-time)- Cytoskeleton, Inc. Employment (full or part-time)- Precision NanoSystems Inc. Employment (full or part-time)- Bio-Rad Research Grant- Korea Food Research Institute

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Author



Disclosure–Institution

Lee, Dong Min Ownership or partnership- Ajou University Lee, Eunjung Employment (full or part-time)- Korea Food Research Institute Lei, Kai Ownership or partnership- Stowers Institute for Medical Research LeMoigne, Ronan Employment (full or part-time)- Cleave Biosciences Leonel, Douglas Alexandre Research Grant- Capes Leonel, Ellen Cristina Research Grant- Fapesp Lereaux, Guillaume Employment (full or part-time)- L’Oreal Lerner, Mitchell Employment (full or part-time)- Nanomedical Diagnostics Leu, Steve Research Grant- Chang Gung Memorial Hospital LeValley, Paige Research Grant- University of Delaware Li, Guodong Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Nil Li, Yunmin Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Xcell Biosciences Inc. Liang, Xue-hai Employment (full or part-time)- IONIS Pharmaceuticals, Inc. Liang, Xue-hai Employment (full or part-time)- Ionis pharmaceutical Liao, Yi-Hua Research Grant- National Science Council, Taiwan Lie, Wen-rong Employment (full or part-time)- MilliporeSigma Lim, James Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Xcell Biosciences Inc. Lin, Charles Employment (full or part-time)- Illumina Lin, Shen Research Grant- Shriners Research Fellowship Lin, Yi-Tzu Research Grant- NIH Liu, Hung Ching Research Grant- Cornell University Lockery, Shawn Stock options or bond holdings in a for-profit corporation or self-directed pension plan- NemaMetrix Inc. Love, Dona Employment (full or part-time)- NIH / NIDDK Ludtke, James Employment (full or part-time)- Mirus Bio LLC Luxton, G.W. Gant Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of Minnesota Ma, Mary Employment (full or part-time)- Bio-Rad Macdonald, Susan Employment (full or part-time)- Aldeyra Therapeutics Macklin, Paul Research Grant- University of Southern California Madriaga, Antonett Employment (full or part-time)- Cleave Biosciences Mahon, Aoife Employment (full or part-time)- SiriusXT Makhanov, Mikhail Employment (full or part-time)- Cellecta, Inc. Makhanov, Mikhail Employment (full or part-time)- Cellecta, Inc. Makhanov, Mikhail Employment (full or part-time)- Cellecta, Inc. Marrot, Laurent Employment (full or part-time)- L’Oreal Martinka, Scott Ownership or partnership- Montana Molecular Matsumoto, Hiroyuki Employment (full or part-time)- Takara Bio USA, Inc. McCormick, Kathryn Employment (full or part-time)- NemaMetrix Inc. McEnroe, Tony Employment (full or part-time)- SiriusXT McKinney, Sean Ownership or partnership- Stowers Institute for Medical Research McMorrow, Tara Employment (full or part-time)- University College Dublin McWilliams-Koeppen, Penney Employment (full or part-time)- ATCC Meluch, Beata Employment (full or part-time)- LGC Biosearch Technologies Menon, Mary Employment (full or part-time)- Cleave Biosciences Mezzache, Sakina Employment (full or part-time)- L’Oreal Middleton, Kim Employment (full or part-time)- Cytoskeleton, Inc. Miller, Zane Employment (full or part-time)- L’Oreal Mlodzik, Marek Research Grant- Icahn School of Medicine at Mount Sinai Mofrad, Mohammad Stock options or bond holdings in a for-profit corporation or self-directed pension plan- UC Berkeley Mofrad, Mohammad Stock options or bond holdings in a for-profit corporation or self-directed pension plan- UC Berkeley Mohan, Ryan Ownership or partnership- Stowers Institute for Medical Research Mon, Aye Research Grant- MUSC Montel, Valerie Employment (full or part-time)- Illumina Mopas, Joshua Employment (full or part-time)- Bio-Rad Moreau-Toussaint, Valerie Employment (full or part-time)- Polyplus-transfection Morell, Montse Employment (full or part-time)- Takara Bio USA Inc. Mori, Masahiro Research Grant- Kakei Educational Institution Morris, Michael Research Grant- US Army Moseley, James Research Grant- NIH Mostowy, Serge Employment (full or part-time)- Imperial College London Motadi, Lesetja Research Grant- SAMRC Moutel, Sandrine Consulting fees or other remuneration- Hybrigenics Services Inventor on a patent application (filled under ref: WO/2015/063331) that covers the hs2dAb scaffold and the commercial use of the library- Institut Curie

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Author



Disclosure–Institution

Müller, Jan Myers, Jamie Nakano, Toshitake Narita, Akihiro Nieto-Lima, Betzabe Niihara, Yutaka Nizard, Carine Noren, Benjamin Nunomura, Wataru Odabasi, Ezgi Okamoto, Norihiro Okamoto, Tevor Olichon, Aurélien

Employment (full or part-time)- IST Austria Employment (full or part-time)- Eagle Applied Sciences Employment (full or part-time)- Saiseikai Toyoura Hospital Research Grant- Government Scholarship- CONACyT: 255108 to NLB Ownership or partnership- Emmaus Life Sciences, Inc. Employment (full or part-time)- LVMH Recherche Research Grant- University of Wyoming Research Grant- JSPS KAKENHI Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Koc University Employment (full or part-time)- Saiseikai Toyoura Hospital Employment (full or part-time)- LGC Biosearch Technologies Inventor on a patent application (filled under ref: WO/2015/063331) that covers the hs2dAb scaffold and the commercial use of the library- INSERM Orjalo, Arturo Employment (full or part-time)- LGC Biosearch Technologies Ouellet, Eric Employment (full or part-time)- Precision NanoSystems Inc. Pan, Chong-xian Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Accelerated Medical Diagnostics Pan, Deng Employment (full or part-time)- Nanomedical Diagnostics Panicker, Leelamma Employment (full or part-time)- ATCC Park, James Employment (full or part-time)- NINDS Patel, Jay Employment (full or part-time)- Illumina Pattamatta, Preeti Employment (full or part-time)- Bio-Rad Peng, Jamy Research Grant- NICHD Pepin, Danielle Employment (full or part-time)- MilliporeSigma Perez, Franck Inventor on a patent application (filled under ref: WO/2015/063331) that covers the hs2dAb scaffold and the commercial use of the library- Institut Curie Perez, Philippe Employment (full or part-time)- L’Oreal Pfanzelter, Julia Employment (full or part-time)- The Francis Crick Institute Podlipaeva, Yulia Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Institute of Cytology Poletti, Mickael Employment (full or part-time)- L’Oreal Poole, Aaron Employment (full or part-time)- L’Oreal Posthuma, George Consulting fees or other remuneration- Genentech Potts, Gregory Employment (full or part-time)- Thermo Fisher Scientific Pradhan, Tirthadipa Research Grant- NIH Prakash, Manu Ownership or partnership- Foldscope Instruments Employment (full or part-time)- Stanford University Priyadarshini, Pallavi Employment (full or part-time)- Bio-Rad Pruss, Rebecca Employment (full or part-time)- TROPHOS Stock options or bond holdings in a for-profit corporation or self-directed pension plan- TROPHOS Qin, Peiwu Stock options or bond holdings in a for-profit corporation or self-directed pension plan- UC Berkeley Quinn, Anne Marie Ownership or partnership- Montana Molecular Rain, Jean-Christophe Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Hybrigenics Services Employment (full or part-time)- Hybrigenics Services Rairdan, Xin Employment (full or part-time)- Genentech Ramsay, Euan Employment (full or part-time)- Precision NanoSystems Inc. Rauniyar, Navin Stock options or bond holdings in a for-profit corporation or self-directed pension plan- The Scripps Research Insistute Reichelt, Mike Employment (full or part-time)- Genentech Retamal, Mauricio Research Grant- CONICYT Rice, Julie Employment (full or part-time)- Cleave Biosciences Rog, Ofer Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of California, Berkeley Rolfe, Mark Employment (full or part-time)- Cleave Biosciences Rosenberg, Scott Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of California, San Diego Rossi, Nicholas Employment (full or part-time)- Mirus Bio LLC Rottner, Klemens Employment (full or part-time)- Technical University Braunschweig Ruiz, Latitia Employment (full or part-time)- L’Oreal Ruppel, Kathleen Consulting fees or other remuneration- Myokardia Ruzicka, Josef Employment (full or part-time)- Thermo Scientific, Inc. Saito, Kan Employment (full or part-time)- EMD Millipore Saliceti-Piazza, Lorenzo Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of Puerto Rico The 2016 ASCB Annual Meeting l www.ascb.org/2016meeting

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Disclosure–Institution

Sánchez Alvarado, Alejandro Scales, Suzie Schlesinger, Felix Schluter, Melissa Schnebert, Sylvianne Schneider, Marie-Laure Schroth, Gary Seidel, Chris Shams, Hengameh Sharma, Jay

Ownership or partnership- Stowers Institute for Medical Research Employment (full or part-time)- Genentech Employment (full or part-time)- Illumina Employment (full or part-time)- MilliporeSigma Employment (full or part-time)- LVMH Recherche Employment (full or part-time)- Innopsys Inc Employment (full or part-time)- Illumina Ownership or partnership- Stowers Institute for Medical Research Stock options or bond holdings in a for-profit corporation or self-directed pension plan- UC Berkeley Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Celprogen Employment (full or part-time)- Celprogen Sharp, David Ownership or partnership- MicroCure Inc. Sheikh, Nadeem Travel Grant- University of the Punjab, Lahore Shen, Wen Employment (full or part-time)- IONIS Pharmaceuticals, Inc. Sheridan, Paul Employment (full or part-time)- SiriusXT Shirai, Yasuhito Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Shirai, Yasuhito Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Simon, Layla Research Grant- Universidad Nacional De Cuyo Sixt, Michael Employment (full or part-time)- IST Austria Smith, Gilbert Employment (full or part-time)- NCI/CCR Soeur, Jeremie Employment (full or part-time)- L’Oreal Soriano, Ferdie Employment (full or part-time)- Cleave Biosciences Soruco, Marcela Employment (full or part-time)- LGC Biosearch Technologies Spudich, James Ownership or partnership- MyoKardia, Inc. and Cytokinetics Inc. Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Cytokinetics, MyoKardia Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Myokardia, Cytokinetics Storck, Austin Employment (full or part-time)- Mirus Bio LLC Stradal, Theresia Employment (full or part-time)- Helmholtz Center for Infection Research Strauss-Soukup, Juliane Research Grant- NIH Strzelecka, Magdalena Employment (full or part-time)- Qiagen Suman, Rakesh Employment (full or part-time)- Phase Focus Limited Sun, Hong Employment (full or part-time)- Ionis pharmaceutical Surma, Michal Employment (full or part-time)- Lipotype, GmbH Ta, Linda Employment (full or part-time)- Genentech Taboga, Sebastião Roberto Employment (full or part-time)- UNESP/Fapesp Tadlock, Lauri Employment (full or part-time)- L’Oreal Tafelmeyer, Petra Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Hybrigenics Services Employment (full or part-time)- Hybrigenics Services Takano, Tetsuya Research Grant- JSPS Takeuchi, Atsuko Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Tang, Yangzhong Employment (full or part-time)- Cleave Biosciences Tanowitz, Michael Employment (full or part-time)- Ionis pharmaceutical Tanter, Mickael Ownership or partnership- L’Oreal Taylor, James Employment (full or part-time)- Precision NanoSystems Inc. Taylor, Kevin Employment (full or part-time)- Illumina Tedesco, Donato Employment (full or part-time)- Cellecta, Inc. Teixiera, Luiz Stock options or bond holdings in a for-profit corporation or self-directed pension plan- IPEN-CNEN/SP Tewson, Paul Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Montana Molecular Thalheim, Tobias Research Grant- Deutsche Forschungsgesellschaft Tharmarajah, Grace Employment (full or part-time)- Precision NanoSystems Inc. Thomas, Anitha Employment (full or part-time)- Precision NanoSystems Inc. Tillo, Shane Ownership or partnership- Montana Molecular Tonnesen, Marcia Non-remunerative positions of influence such as officer, board member, trustee, or public spokesperson- Neomatrix Therapeutics, Inc. Stony Brook, NY 11790 Trosan, Peter Research Grant- Grant Agency of the Czech Republic 14-12580S Tsai, Jeff Employment (full or part-time)- Illumina Turner, Carl Employment (full or part-time)- NemaMetrix Inc. Ubukawa, Kumi Research Grant- JSPS KAKENHI Ueda, Shuji Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Uhlén, Mathias Ownership or partnership- Antibodypedia Usluer, Gulsima Stock options or bond holdings in a for-profit corporation or self-directed pension plan- University of Washington Usukura, Eiji Research Grant- Government Usukura, Jiro Research Grant- Government

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Author



Disclosure–Institution

Valencia, Sara Valle, Eduardo Valtier, Sandra van Westrienen, Jesse Vieira, Cristiano von Feilitzen, Kalle Vu, Hanh Wakui, Hideki Walker, Amy Wang, Jinhai Wang, Shiyu Watson, Lisa Way, Michael Webb, Alexis Wiktor, Jakub Wild, Andre Wilde, Andrew Williams, Sparkle Willis, Adam Winterhoff, Moritz Wordinger, Robert Workman, Jerry Wu, Zhi Yong Wustrow, David Xia, Hui Xiao, Qiang Yagi, Akira Yamada, Soichiro Yamagami, Takashi Yamanoue, Minoru Yamanoue, Minoru Yang, Xiaoyang Yao, Bing Yates iii, John

Research Grant- California State University Long Beach Employment (full or part-time)- Cleave Biosciences Research Grant- US Air Force Employment (full or part-time)- Biomeme Research Grant- FAPESP - Foundation for Research of the State of São Paulo Ownership or partnership- Antibodypedia Ownership or partnership- Stowers Institute for Medical Research Research Grant- JSPS KAKENHI Employment (full or part-time)- Nanomedical Diagnostics Employment (full or part-time)- Cleave Biosciences Employment (full or part-time)- Ionis pharmaceutical Employment (full or part-time)- Illumina Employment (full or part-time)- The Francis Crick Institute Employment (full or part-time)- NemaMetrix Inc. Employment (full or part-time)- TU Delft Employment (full or part-time)- Precision NanoSystems Inc. Research Grant- Natural Sciences and Engineering Research Council of Canada Employment (full or part-time)- UAB Research Grant- US Air Force Research Grant- Deutsche Forschungsgesellschaft Research Grant- NIH Ownership or partnership- Stowers Institute for Medical Research Employment (full or part-time)- Cleave Biosciences Employment (full or part-time)- Cleave Biosciences Employment (full or part-time)- Eagle Applied Sciences Employment (full or part-time)- MilliporeSigma Employment (full or part-time)- Olympus Corporation Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Employment (full or part-time)- Precision NanoSystems Inc. Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Employment (full or part-time)- St. Jude Hospital Employment (full or part-time)- Cleave Biosciences Stock options or bond holdings in a for-profit corporation or self-directed pension plan- The Scripps Research Institute Yin, Dezhong Employment (full or part-time)- ATCC Yin, Raymund Employment (full or part-time)- LGC Biosearch Technologies Yoshino, Ken-ichi Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Kobe University Young, Scott Employment (full or part-time)- Aldeyra Therapeutics Yun, Jun-Won Research Grant- KHIDI Yunghans, Allison Employment (full or part-time)- Illumina Zajicova, Alena Research Grant- Grant Agency of the Czech Republic 14-12580S Zanini, Martine Employment (full or part-time)- L’Oreal Zhang, Bin Employment (full or part-time)- Bio-Rad Zhang, Haolin Research Grant- This study was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (to KN, 26660248) and Health and Labour Science Research Grants, Research on Risk of Chemical Substance, Ministry of Health, Labour and Zhou, Han-Jie Employment (full or part-time)- Cleave Biosciences Zimmermann, Maike Stock options or bond holdings in a for-profit corporation or self-directed pension plan- Accelerated Medical Diagnostics Zobiri, Olivia Employment (full or part-time)- L’Oreal

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